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Found 89 with Last Name = 'carlson' and Initial = 'je'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119448(US8686018, 107)
Affinity DataKi:  8nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119450(US8686018, 109)
Affinity DataKi:  8nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119451(US8686018, 110)
Affinity DataKi:  10nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119449(US8686018, 108)
Affinity DataKi:  13nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119444(US8686018, 103)
Affinity DataKi:  14nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119446(US8686018, 105)
Affinity DataKi:  16nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119452(US8686018, 111)
Affinity DataKi:  26nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119445(US8686018, 104)
Affinity DataKi:  43nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM119447(US8686018, 106)
Affinity DataKi:  50nMpH: 7.4Assay Description:The radioligand EP4 binding assay was performed using ChemiScreen recombinant human EP4 receptor membrane preparations from Millipore, according to m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073885(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073886(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073892(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073881(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073893(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073890(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073895(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073888(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  34nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073903(1-Mercaptomethyl-4-methoxy-cyclohexanecarboxylic a...)
Affinity DataIC50:  35nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073906(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  39nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073904(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073894(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  42nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073906(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  46nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073894(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  47nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073893(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073883(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073885(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  52nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073905(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  52nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073881(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  62nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073900(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  63nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073887(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  66nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073886(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  73nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073883(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  76nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073900(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  77nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073889(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  79nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073882(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  79nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073899(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  81nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073891(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  83nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073905(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  87nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073897(1-Mercaptomethyl-4-trifluoromethyl-cyclohexanecarb...)
Affinity DataIC50:  108nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073903(1-Mercaptomethyl-4-methoxy-cyclohexanecarboxylic a...)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073889(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  113nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073902(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  121nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073891(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  134nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073886(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  135nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073888(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  139nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073899(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  175nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073898(1-Mercaptomethyl-4-propoxy-cyclohexanecarboxylic a...)
Affinity DataIC50:  187nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073895(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  207nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073887(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  223nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073884(1-Mercaptomethyl-cyclohexanecarboxylic acid ((S)-1...)
Affinity DataIC50:  350nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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