TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity for Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity for Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Binding affinity for Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity for Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity for Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Binding affinity for Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type 2 from human BPH tissue at 210 nM of testosteroneMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human Cytochrome P450 17More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type I in human DU-145 cell assay at 5 nM of androstenedioneMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of Human steroid 5-alpha-reductase type II expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 rat enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of thromboxane synthase P450 TXA2More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of rat Cytochrome P450 17More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of Human P450 17 and NADPH-P450 reductase co-expressed in Escherichia coli with 25 uM progesteroneMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 rat enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type 2 from human BPH tissue at 210 nM of testosteroneMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of Human P450 17 and NADPH-P450 reductase co-expressed in Escherichia coli with 25 uM progesteroneMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type 2 from human BPH tissue at 210 nM of testosteroneMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type 2 from human BPH tissue at 210 nM of testosteroneMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type 2 from human BPH tissue at 210 nM of testosteroneMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Inhibition of Human P450 17 and NADPH-P450 reductase co-expressed in Escherichia coli with 25 uM progesteroneMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 rat enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of Human steroid 5-alpha-reductase type I expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type 2 from human BPH tissue at 210 nM of testosteroneMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type 2 from human BPH tissue at 210 nM of testosteroneMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of Human steroid 5-alpha-reductase type II expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of Human steroid 5-alpha-reductase type II expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type I in human DU-145 cell assay at 5 nM of androstenedioneMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type I in human DU-145 cell assay at 5 nM of androstenedioneMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 970nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
University Of The Saarland
Curated by ChEMBL
University Of The Saarland
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of P450 sccMore data for this Ligand-Target Pair