Compile Data Set for Download or QSAR
maximum 50k data
Found 665 with Last Name = 'murphy' and Initial = 'r'
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0150nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012965(5-Iodo-2,3-dihydro-benzofuran-7-carboxylic acid (1...)
Affinity DataKi:  0.0850nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012965(5-Iodo-2,3-dihydro-benzofuran-7-carboxylic acid (1...)
Affinity DataKi:  0.230nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)
Affinity DataKi:  0.261nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Creighton University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50001447(CHEMBL217406 | His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu...)
Affinity DataKi:  0.710nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
New York University

Curated by ChEMBL
LigandPNGBDBM50007400(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Affinity DataKi:  1nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]-haloperidol in the presence of 25 nM unlabeled spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.10nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50366495((+)butaclamol | CHEMBL1255588)
Affinity DataKi:  1.20nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50010720(5-Bromo-2,3-dihydro-benzofuran-7-carboxylic acid (...)
Affinity DataKi:  3.90nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
New York University

Curated by ChEMBL
LigandPNGBDBM50002218(2-(1-Cyclopropylmethyl-piperidin-4-yl)-1-(4-fluoro...)
Affinity DataKi:  10nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]- haloperidolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
New York University

Curated by ChEMBL
LigandPNGBDBM50002245(4-[2-(1-Cyclopropylmethyl-piperidin-4-yl)-acetyl]-...)
Affinity DataKi:  10nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]- haloperidolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Creighton University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50079406(Asp-Thr-D-Phe-Val-Gly-Leu-Nle-NH2 | Asp-Thr-Phe-Va...)
Affinity DataKi:  13nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012962(3-Methoxy-naphthalene-2-carboxylic acid (1-ethyl-p...)
Affinity DataKi:  30nMAssay Description:In vivo compound was evaluated for binding towards Dopamine receptor D2 in rat striatal membranes using competitive binding assay and [125I]IBZM radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Creighton University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50079412((NKB)Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 |...)
Affinity DataKi:  42nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Creighton University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50079409(Asp-Thr-p-F-Phe-Val-Gly-Leu-Nle-NH2 | CHEMBL103634)
Affinity DataKi:  44nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345738(1-isopropyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]...)
Affinity DataKi:  65nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81195((+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaph...)
Affinity DataKi:  66nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345738(1-isopropyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]...)
Affinity DataKi:  69nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012971(7-Bromo-3-methoxy-naphthalene-2-carboxylic acid (1...)
Affinity DataKi:  82nMAssay Description:In vivo compound was evaluated for binding towards Dopamine receptor D2 in rat striatal membranes using competitive binding assay and [125I]IBZM radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Creighton University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50001450((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...)
Affinity DataKi:  102nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012959(2,3-Dihydro-benzofuran-7-carboxylic acid (1-ethyl-...)
Affinity DataKi:  135nMAssay Description:In vivo compound was evaluated for binding towards Dopamine receptor D2 in rat striatal membranes using competitive binding assay and [125I]IBZM radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Creighton University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50079408(Asp-Thr-p-NH2-Phe-Val-Gly-Leu-Nle-NH2 | CHEMBL1039...)
Affinity DataKi:  156nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012963(7-Iodo-3-methoxy-naphthalene-2-carboxylic acid (1-...)
Affinity DataKi:  168nMAssay Description:In vivo compound was evaluated for binding towards Dopamine receptor D2 in rat striatal membranes using competitive binding assay and [125I]IBZM radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345742(1-isopropyl-3-(quinolin-3-yl)-1H-pyrazolo[3,4-d]py...)
Affinity DataKi:  200nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345740(3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazol...)
Affinity DataKi:  200nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012960(7-Bromo-3-hydroxy-naphthalene-2-carboxylic acid (1...)
Affinity DataKi:  280nMAssay Description:In vivo compound was evaluated for binding towards Dopamine receptor D2 in rat striatal membranes using competitive binding assay and [125I]IBZM radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383382(CHEMBL2030556 | CHEMBL2069948 | US10172858, Table ...)
Affinity DataKi:  280nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
Affinity DataKi:  491nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012970(2-Methoxy-naphthalene-1-carboxylic acid (1-ethyl-p...)
Affinity DataKi:  507nMAssay Description:In vivo compound was evaluated for binding towards Dopamine receptor D2 in rat striatal membranes using competitive binding assay and [125I]IBZM radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345735(1-isopropyl-3-(4-methoxy-3-methylphenyl)-1H-pyrazo...)
Affinity DataKi:  650nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)
Affinity DataKi:  750nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)
Affinity DataKi:  770nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM82247(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)
Affinity DataKi:  820nMAssay Description:In vivo compound was evaluated for binding towards Dopamine receptor D2 in rat striatal membranes using competitive binding assay and [125I]IBZM radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataKi:  843nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
New York University

Curated by ChEMBL
LigandPNGBDBM50002245(4-[2-(1-Cyclopropylmethyl-piperidin-4-yl)-acetyl]-...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Dopamine receptor D2 in bovine striatal homogenate using 200 pM [3H]- spiperone and 250 nM unlabeled ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
New York University

Curated by ChEMBL
LigandPNGBDBM50002218(2-(1-Cyclopropylmethyl-piperidin-4-yl)-1-(4-fluoro...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Dopamine receptor D2 in bovine striatal homogenate using 200 pM [3H]- spiperone and 250 nM unlabeled ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383382(CHEMBL2030556 | CHEMBL2069948 | US10172858, Table ...)
Affinity DataKi:  1.24E+3nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Creighton University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50079410(Asp-Thr-p-Cl-Phe-Val-Gly-Leu-Nle-NH2 | CHEMBL10212...)
Affinity DataKi:  1.42E+3nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345742(1-isopropyl-3-(quinolin-3-yl)-1H-pyrazolo[3,4-d]py...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345740(3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazol...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Creighton University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50079411(Asp-Thr-p-NO2-Phe-Val-Gly-Leu-Nle-NH2 | CHEMBL4306...)
Affinity DataKi: >2.00E+3nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Creighton University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50079407(Asp-Thr-Trp-Val-Gly-Leu-Nle-NH2 | CHEMBL319256)
Affinity DataKi: >2.00E+3nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Creighton University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50408715(CHEMBL2111616)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity towards NK-2 receptors using [3H]NKA as radioligand in cloned human CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50180753((5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid met...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383376(CHEMBL2030558 | CHEMBL2069945 | US10544104, Compou...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US10544104, Compound 92 | US976503...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383379(CHEMBL2030552 | CHEMBL2069958 | US9518026, Example...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50180753((5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid met...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US10544104, Compound 92 | US976503...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383378(CHEMBL2030561)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 665 total ) | Next | Last >>
Jump to: