BindingDB PrimarySearch_ki

Found 553 with Last Name = 'stratikos' and Initial = 'e'

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50236826(CHEMBL4065841)

Ki: 18nMAssay Description:Inhibition of recombinant human IRAP expressed in GnT1 deficient HEK293S cells using L-leucine 7-amido-4-methyl coumarin as substrate after 5 to 10 m...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50236826(CHEMBL4065841)

Ki: 200nMAssay Description:Inhibition of recombinant human ERAP2 using L-arginyl-7-amido-4-methyl coumarin as substrate by fluorimetric assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529326(CHEMBL4557197)

Ki: 700nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529330(CHEMBL4527760)

Ki: 1.20E+3nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50529330(CHEMBL4527760)

Ki: 1.30E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50529329(CHEMBL4560993)

Ki: 3.20E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50236826(CHEMBL4065841)

Ki: 3.50E+3nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50529320(CHEMBL4540943)

Ki: 3.80E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50519953(CHEMBL2140832)

Ki: 3.80E+3nMAssay Description:Competitive inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using varying le...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase PC cid PC sid

Details Article PubMed

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529320(CHEMBL4540943)

Ki: 4.30E+3nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50529322(CHEMBL4466281)

Ki: 4.60E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529323(CHEMBL4452852)

Ki: 4.70E+3nMAssay Description:Competitive inhibition of human recombinant ERAP1 expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529321(CHEMBL4575946)

Ki: 4.80E+3nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529325(CHEMBL4436776)

Ki: 4.90E+3nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50529326(CHEMBL4557197)

Ki: 5.70E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50529328(CHEMBL4475441)

Ki: 8.70E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529330(CHEMBL4527760)

Ki: 1.09E+4nMAssay Description:Competitive inhibition of human recombinant ERAP1 expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50519944(CHEMBL4456470)

Ki: 1.28E+4nMAssay Description:Competitive inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using varying le...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50529324(CHEMBL4445197)

Ki: 1.30E+4nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid PDB

Details Article PubMed

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529328(CHEMBL4475441)

Ki: 1.74E+4nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529324(CHEMBL4445197)

Ki: 1.75E+4nMAssay Description:Competitive inhibition of human recombinant ERAP1 expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50529325(CHEMBL4436776)

Ki: 1.76E+4nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529327(CHEMBL4455738)

Ki: 1.77E+4nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed

Endoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529326(CHEMBL4557197)

Ki: 1.85E+4nMAssay Description:Competitive inhibition of human recombinant ERAP1 expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529331(CHEMBL4535014)

Ki: 2.14E+4nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529328(CHEMBL4475441)

Ki: 2.34E+4nMAssay Description:Competitive inhibition of human recombinant ERAP1 expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529324(CHEMBL4445197)

Ki: 2.74E+4nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed

Endoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50529325(CHEMBL4436776)

Ki: 4.40E+4nMAssay Description:Competitive inhibition of human recombinant ERAP1 expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Endoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50519948(CHEMBL1700161)

Ki: 5.17E+4nMAssay Description:Competitive inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using varying le...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245396(CHEMBL4101200)

IC50: 2nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245391(CHEMBL4095882)

IC50: 4nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)

IC50: 5nMAssay Description:Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Leu-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50601034(CHEMBL5191661)

IC50: 6.5nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid PDB

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245390(CHEMBL4077855)

IC50: 9nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245400(CHEMBL4099107)

IC50: 10nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Endoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50076744(CHEMBL3416733)

IC50: 11nMAssay Description:Inhibition of human recombinant ERAP2 expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-arginyl-7-amido-4-methyl coumarin as s...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Patents

Details Article PubMed PDB

3D Structure (crystal)

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245382(CHEMBL4080145)

IC50: 13nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50601033(CHEMBL5209483)

IC50: 13nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245388(CHEMBL4081073)

IC50: 13nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245349(CHEMBL4089555)

IC50: 14nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)

IC50: 16nMAssay Description:Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Arg-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245428(CHEMBL4069576)

IC50: 16nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245399(CHEMBL4069425)

IC50: 18nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Interleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL

PNG

BDBM50601042(CHEMBL5195885)

IC50: 19nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245383(CHEMBL4104383)

IC50: 20nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245446(CHEMBL4094131)

IC50: 21nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245354(CHEMBL4097268)

IC50: 29nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50076744(CHEMBL3416733)

IC50: 30nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as su...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Patents

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50245347(CHEMBL4081682)

IC50: 32nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Leucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL

PNG

BDBM50236826(CHEMBL4065841)

IC50: 32nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Displayed 1 to 50 (of 553 total ) | Next | Last >>

Filter my 553 hits

Targets 4▿
- Endoplasmic reticulum aminopeptidase 1 181
- Endoplasmic reticulum aminopeptidase 2 180
- Leucyl-cystinyl aminopeptidase 114
- Interleukin-1 receptor antagonist protein 78
Publications 11▿
- J Med Chem 58: 1524-43 (2015) 171
- J Med Chem 65: 10098-10117 (2022) 109
- J Med Chem 59: 9107-9123 (2016) 93
- J Med Chem 63: 103-121 (2020) 70
- Bioorg Med Chem 27: (2019) 55
- Bioorg Med Chem Lett 23: 4832-6 (2013) 22
- ACS Med Chem Lett 7: 681-5 (2016) 14
- J Med Chem 63: 3348-3358 (2020) 7
- ACS Med Chem Lett 11: 1429-1434 (2020) 6
- ACS Med Chem Lett 8: 333-337 (2017) 3
- J Med Chem 60: 2963-2972 (2017) 3
Institutions 7▿
- National Center For Scientific Research&Quot;Demokritos&Quot 171
- National Centre For Scientific Research "Demokritos 164
- National and Kapodistrian University of Athens 93
- Kansas University Specialized Chemistry Center 70
- National Center For Scientific Research Demokritos 26
- University Of California San Diego 22
- Glaxosmithkline 7
Affinity: 2 to 1.0E+6 nM▿
- Ki 29
- IC50 524
- Affinity ≤ nM
Xtal structures: 10
Docked structures: 0
Catalog Cmpds: 8