Compile Data Set for Download or QSAR
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Found 36 Enz. Inhib. hit(s) with all data for entry = 50008841
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522805(CHEMBL4514272)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM151212(US8987314, B3)
Affinity DataIC50:  5nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522804(CHEMBL4437751)
Affinity DataIC50:  7nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM319015(N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluor...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human endothelial lipase using D31-POPC-HDL as substrate incubated for 2 hrs in presence of human serum by LC/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM151303(US8987314, B101)
Affinity DataIC50:  10nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM151238(US8987314, B34)
Affinity DataIC50:  10nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522808(CHEMBL4520847)
Affinity DataIC50:  10nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522808(CHEMBL4520847)
Affinity DataIC50:  15nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522804(CHEMBL4437751)
Affinity DataIC50:  25nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM319014(N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluor...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM319543(N-[(cyclopropyl- carbamoyl) methyl]-2- methanesulf...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM319015(N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluor...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522806(CHEMBL4438013)
Affinity DataIC50:  52nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522804(CHEMBL4437751)
Affinity DataIC50:  65nMAssay Description:Inhibition of human endothelial lipase using D31-POPC-HDL as substrate incubated for 2 hrs in presence of human serum by LC/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM319014(N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluor...)
Affinity DataIC50:  79nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522807(CHEMBL4461739)
Affinity DataIC50:  81nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522805(CHEMBL4514272)
Affinity DataIC50:  83nMAssay Description:Inhibition of human endothelial lipase using D31-POPC-HDL as substrate incubated for 2 hrs in presence of human serum by LC/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522804(CHEMBL4437751)
Affinity DataIC50:  94nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522808(CHEMBL4520847)
Affinity DataIC50:  100nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522805(CHEMBL4514272)
Affinity DataIC50:  120nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM319015(N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluor...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM319543(N-[(cyclopropyl- carbamoyl) methyl]-2- methanesulf...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM151238(US8987314, B34)
Affinity DataIC50:  190nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM151212(US8987314, B3)
Affinity DataIC50:  200nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522805(CHEMBL4514272)
Affinity DataIC50:  230nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM151303(US8987314, B101)
Affinity DataIC50:  280nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM319015(N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluor...)
Affinity DataIC50:  290nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522805(CHEMBL4514272)
Affinity DataIC50:  310nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasma using D31-POPC-HDL as substrate incubated for 2 hrs by LC/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM151238(US8987314, B34)
Affinity DataIC50:  310nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM151303(US8987314, B101)
Affinity DataIC50:  320nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522807(CHEMBL4461739)
Affinity DataIC50:  450nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM319014(N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluor...)
Affinity DataIC50:  600nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM319014(N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluor...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human endothelial lipase using D31-POPC-HDL as substrate incubated for 2 hrs in presence of human serum by LC/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM151212(US8987314, B3)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522806(CHEMBL4438013)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50522805(CHEMBL4514272)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of hepatic lipase in endothelial lipase knock-out mouse plasma using D31-POPC-HDL as substrate incubated for 2 hrs by LC/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed