Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 2844
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138357(US10278929, Compound 6 | US11337935, Compound 6 | ...)
Affinity DataIC50:  277nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM85507(CAS_4394-00-7 | NSC_4488 | Niflumic acid | Niflumi...)
Affinity DataIC50:  289nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138358(US10278929, Compound 7 | US11337935, Compound 7 | ...)
Affinity DataIC50:  296nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50308343((Z)-5-(3,5-dibromo-4-methoxybenzylidene)thiazolidi...)
Affinity DataIC50:  301nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138359(US10278929, Compound 9 | US11337935, Compound 9 | ...)
Affinity DataIC50:  329nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138360(US10278929, Compound 10 | US11337935, Compound 10 ...)
Affinity DataIC50:  433nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM383181(US10278929, Meclofenamic acid)
Affinity DataIC50:  504nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM58032(2-(1,3-Dioxo-indan-2-yl)-2-(2-methyl-1H-indol-3-yl...)
Affinity DataIC50:  586nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  653nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50017846(3,5-DINITROCATECHOL | 3,5-Dinitro-benzene-1,2-diol...)
Affinity DataIC50:  741nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138363(US10278929, Compound Ro-41-0960 | US11337935, Comp...)
Affinity DataIC50:  755nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138364(US10278929, Compound 12 | US11337935, Compound 12 ...)
Affinity DataIC50:  815nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50334179(5-(naphthalen-1-ylmethylene)thiazolidine-2,4-dione...)
Affinity DataIC50:  842nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138365(US10278929, Compound 14 | US11337935, Compound 14 ...)
Affinity DataIC50:  1.15E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138366(US10278929, Compound 15 | US11337935, Compound 15 ...)
Affinity DataIC50:  1.31E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138367(US10278929, Compound 16 | US11337935, Compound 16 ...)
Affinity DataIC50:  2.59E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138368(US10278929, Compound 17 | US11337935, Compound 17 ...)
Affinity DataIC50:  2.66E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138369(US10278929, Compound 18 | US11337935, Compound 18 ...)
Affinity DataIC50:  3.35E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138370(US10278929, Compound 19 | US11337935, Compound 19 ...)
Affinity DataIC50:  3.71E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138371(US10278929, Diclofenac | US8877795, Diclofenac)
Affinity DataIC50:  3.74E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138372(US10278929, Compound 20 | US11337935, Compound 20 ...)
Affinity DataIC50:  3.93E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138373(US10278929, Compound 21 | US11337935, Compound 21 ...)
Affinity DataIC50:  4.22E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50355116(CHEMBL493923 | US10278929, Compound 22 | US1133793...)
Affinity DataIC50:  4.79E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138374(US10278929, Compound 23 | US11337935, Compound 23 ...)
Affinity DataIC50:  4.88E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138375(US10278929, Compound 24 | US11337935, Compound 24 ...)
Affinity DataIC50:  4.93E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138376(US10278929, Compound 25 | US11337935, Compound 25 ...)
Affinity DataIC50:  5.41E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138377(US10278929, Compound 26 | US11337935, Compound 26 ...)
Affinity DataIC50:  5.60E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138378(US10278929, Compound 27 | US11337935, Compound 27 ...)
Affinity DataIC50:  5.80E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138379(US10278929, Compound 28 | US11337935, Compound 28 ...)
Affinity DataIC50:  8.69E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138380(US10278929, Compound 29 | US11337935, Compound 29 ...)
Affinity DataIC50:  9.76E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138381(US10278929, Compound 30 | US11337935, Compound 30 ...)
Affinity DataIC50:  1.00E+4nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138382(US10278929, Compound 31 | US11337935, Compound 31 ...)
Affinity DataIC50:  1.06E+4nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138383(US10278929, Compound 32 | US11337935, Compound 32 ...)
Affinity DataIC50:  1.10E+4nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138371(US10278929, Diclofenac | US8877795, Diclofenac)
Affinity DataKd:  370nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138358(US10278929, Compound 7 | US11337935, Compound 7 | ...)
Affinity DataKd:  320nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138363(US10278929, Compound Ro-41-0960 | US11337935, Comp...)
Affinity DataKd:  184nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138365(US10278929, Compound 14 | US11337935, Compound 14 ...)
Affinity DataKd:  245nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM85507(CAS_4394-00-7 | NSC_4488 | Niflumic acid | Niflumi...)
Affinity DataKd:  592nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM383209(US10278929, Compound 5 | US11337935, Compound 5)
Affinity DataKd:  820nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM383208(US10278929, Compound 4 | US11337935, Compound 4)
Affinity DataKd:  285nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM383210(US10278929, Compound 1 | US11337935, Compound 1)
Affinity DataKd:  72.5nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair