Search by Compound Name
Compounds Sorted by Binding Targets per Compound
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 2930 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 73 74 75 76 77 79 81 84 86 89 95
96 100 108 109 120 124 130 137 143 154 156 168 186 224 240 259 276 278 284 303
304 310 315 323 339 369 370 371 372 373 374 375 376 377 378 380 381 383 384
385 386 388 389 390 391 392 393 394 395 397 398 401 403 404 406 408 418 427
429 443 447 515
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
- Coagulation factor X
- Coagulation factor XI
- Coagulation factor XII
- Complement C1r
- Complement C1r subcomponent
- Complement C1s
- Factor XIIa
- Plasma kallikrein
- Plasminogen
- Prothrombin
- Tissue-type plasminogen activator
- Transcription initiation factor IIA
- Vitamin K-dependent protein C
20 Ki
- US8598206, Table 6, 7
- 72 kDa type IV collagenase
- Bile salt export pump
- Collagenase 3
- Disintegrin and metalloproteinase domain-containing protein 17
- Interstitial collagenase
- Matrix metalloproteinase 10
- Matrix metalloproteinase 14
- Matrix metalloproteinase 7
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-7 (MMP7)
- Matrix metalloproteinase-9
- Neutrophil collagenase
- Stromelysin-1
- 4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N-hydroxyoxane-4-carboxamide
- CHEMBL440498
- RS 130830
- RS-130,830
- alpha-tetrahydropyran beta-sulfone 1B
- Cathepsin B
- Cathepsin F
- Cathepsin K
- Cathepsin L2
- Cathepsin S
- Chymase
- Elastase 1
- HCV NS3-NS4A Serine Proteinase
- Leukocyte elastase
- Nonstructural protein NS3-4A
- Plasminogen
- Procathepsin L
- Replicase polyprotein 1ab
- (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide
- 3-{[(1R,2S,5S)-3-[(2S)-2-[(tert-butylcarbamoyl)amino]-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2-yl]formamido}-4-cyclobutyl-2-oxobutanamide
- BOCEPREVIR
- SCH 503034
- Cytochrome P450 1A
- Cytochrome P450 2B6
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Fibroblast growth factor receptor 1
- Prostaglandin E2 receptor
- Prostaglandin E2 receptor EP1 subtype (EP1)
- Prostaglandin E2 receptor EP2 subtype
- Prostaglandin E2 receptor EP4 subtype
- Prostanoid EP4 receptor
- US8933098, 1
- US8933099, 1
- 5-hydroxytryptamine receptor 2A
- Axin-1/Glycogen synthase kinase-3 beta
- Calmodulin/Proto-oncogene tyrosine-protein kinase Src
- Glycogen synthase kinase-3
- Glycogen synthase kinase-3 beta
- Mitogen-activated protein kinase 12
- Mitogen-activated protein kinase 12 Gamma
- Mitogen-activated protein kinase 14
- Proto-oncogene tyrosine-protein kinase Src
- SRC
- Tyrosine-protein kinase HCK
- Tyrosine-protein kinase SYK
- hck
- US10238658, Example Reference
- US10813932, Reference Compound
- US8933228, Ref 2
- US9242960, 1
- US9249125, Reference Compound
- US9701670, Reference Compound
- US9724347, Example Reference
- US9993478, Example Reference
- ATP-sensitive inward rectifier potassium channel 1
- ATP-sensitive inward rectifier potassium channel 10
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Inward rectifier potassium channel 13
- Inward rectifier potassium channel 2
- Inward rectifier potassium channel 4
- Potassium voltage-gated channel subfamily H member 2
- Renal Outer Medullary Potassium (ROMK)
- Sodium channel protein type 2 alpha subunit
- Sodium channel protein type 7 subunit alpha
16 IC50
- US9018211, 52
- Acyl coenzyme A:cholesterol acyltransferase
- Anandamide amidohydrolase
- Arylacetamide deacetylase
- Carboxylesterase 2
- EBifunctional epoxide hydrolase 2
- Epoxide hydratase
- Epoxide hydrolase 1
- Epoxide hydrolase 2
- Fatty-acid amide hydrolase 1
- RAF proto-oncogene serine/threonine-protein kinase
- Serum paraoxonase/arylesterase 1
- Serum paraoxonase/arylesterase 2
- Serum paraoxonase/lactonase 3
- US9029401, 1728 (t-TUCB)
- Amine oxidase (flavin-containing) A
- E3 ubiquitin-protein ligase XIAP/JAK1
- E3 ubiquitin-protein ligase XIAP/JAK2
- JAK1/JAK2/TYK2
- JAK1/TYK2
- JAK2/JAK1
- JAK2/TYK2
- JAK3/JAK1
- Non-receptor tyrosine-protein kinase TYK2
- Tyrosine-protein kinase JAK1
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
- Vascular endothelial growth factor receptor 2
27 IC50
- US9035074, 2
- 5-hydroxytryptamine receptor 2A
- Axin-1/Glycogen synthase kinase-3 beta
- Calmodulin/Proto-oncogene tyrosine-protein kinase Src
- Glycogen synthase kinase-3
- Glycogen synthase kinase-3 beta
- Mitogen-activated protein kinase 12
- Mitogen-activated protein kinase 12 Gamma
- Mitogen-activated protein kinase 14
- Proto-oncogene tyrosine-protein kinase Src
- SRC
- Tyrosine-protein kinase HCK
- Tyrosine-protein kinase SYK
- hck
- US10238658, Example 1
- US10813932, Example 1
- US9108950, 1
- US9724347, Example 1
- US9993478, Example 1
- Angiopoietin-1 receptor
- Fibroblast growth factor receptor 1
- Hepatocyte growth factor receptor
- Insulin-like growth factor I receptor
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 14
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase BTK
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase ZAP-70
- Vascular endothelial growth factor receptor 2
13 IC50
- 2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}amino)pyrimidin-4-yl]-N-(2,4-dimethoxyphenyl)carbamate
- 2-aminopyrimidine carbamate, 43
- 6His.FMS.538-922(FGFR)
- Alpha-synuclein
- Beta amyloid A4 protein
- Epidermal growth factor receptor
- Insulin-like growth factor I receptor
- Luciferin 4-monooxygenase
- Macrophage colony-stimulating factor 1 receptor (aa 538-972)
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Receptor tyrosine-protein kinase erbB-2
- Tau
- Vascular endothelial growth factor receptor 1
- cFMS -Tie-2 Chimera
- (3Z)-3-{[4-(dimethylamino)phenyl]methylidene}-2,3-dihydro-1H-indol-2-one
- CHEMBL328710
- SU 4312
- SU4312
- Androgen Receptor
- Androgen receptor
- Corticosteroid-binding globulin
- Cytochrome P450 19A1
- Estrogen receptor
- G-protein coupled bile acid receptor 1
- Glucocorticoid
- Glucocorticoid receptor
- Mineralocorticoid receptor
- Organic anion-transporting polypeptide 1D1 (Oatp1d1)
- Progesterone receptor
- Testis-specific androgen-binding protein
- mineralocorticoid
- (1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one
- (5alpha,17beta)-17-hydroxyandrostan-3-one
- CHEMBL27769
- DHT
- Dihydrotestosterone
- [3H]DHT
- 5-hydroxytryptamine receptor 1A (5HT1A)
- 5-hydroxytryptamine receptor 1D (5HT1D)
- 5-hydroxytryptamine receptor 2A (5HT2A)
- 5-hydroxytryptamine receptor 2B (5HT2B)
- 5-hydroxytryptamine receptor 2C (5HT2C)
- 5-hydroxytryptamine receptor 7 (5HT7)
- Alpha-1A adrenergic receptor
- Alpha-1B adrenergic receptor
- Alpha-1D adrenergic receptor
- D(2) dopamine receptor
- Dopamine D1 receptor
- Dopamine D3 receptor
- Dopamine D4 receptor
13 Ki
- US9079895, 19s
- Coagulation factor III/Factor VIIa (fVIIa)
- Coagulation factor IX
- Coagulation factor VII
- Coagulation factor X
- Coagulation factor XI
- Coagulation factor XII
- Kallikrein 1
- Plasma kallikrein
- Plasminogen
- Prothrombin
- Tissue-type plasminogen activator
- Urokinase-type plasminogen activator/surface receptor
- Vitamin K-dependent protein C
14 Ki
- US9174974, Example 19
- Cereblon/Histone deacetylase 1
- Cereblon/Histone deacetylase 2
- Cereblon/Histone deacetylase 6
- Histone deacetylase
- Histone deacetylase 1
- Histone deacetylase 10
- Histone deacetylase 2
- Histone deacetylase 3
- Histone deacetylase 4
- Histone deacetylase 5
- Histone deacetylase 7
- Histone deacetylase 8
- Histone deacetylase 9
- HDAC inhibitor, Compound 1
- N-[2-amino-5-(thiophen-2-yl)phenyl]-4-acetamidobenzamide
- N-[2-amino-5-(thiophen-2-yl)phenyl]-4-acetamidobenzamide (60)
- SHI-1:2
- benzamide-type inhibitor, 19
- BET bromodomain 2(1) (BRD2(1))
- BET bromodomain 2(1,2) (BRD2(1,2))
- BET bromodomain 2(2) (BRD2(2))
- BET bromodomain 3(1) (BRD3(1))
- BET bromodomain 3(1,2) (BRD3(1,2))
- BET bromodomain 3(2) (BRD3(2))
- BET bromodomain 4 (BRD4)
- BET bromodomain 4(1,2) (BRD4(1,2))
- Bromodomain testis (1, 2) (BRDT(1,2))
- Bromodomain testis 1 (BRDT(1))
- Bromodomain testis 2 (BRDT(2))
- Bromodomain-containing protein 4 (BRD4)
- Bromodomain-containing protein 4 (BRD4) (aa 44-168)
1 ΔG°
- (6S+2S)-PEG1 (7)
- BET bromodomain 2(1) (BRD2(1))
- BET bromodomain 2(1,2) (BRD2(1,2))
- BET bromodomain 2(2) (BRD2(2))
- BET bromodomain 3(1) (BRD3(1))
- BET bromodomain 3(1,2) (BRD3(1,2))
- BET bromodomain 3(2) (BRD3(2))
- BET bromodomain 4 (BRD4)
- BET bromodomain 4(1,2) (BRD4(1,2))
- Bromodomain testis (1, 2) (BRDT(1,2))
- Bromodomain testis 1 (BRDT(1))
- Bromodomain testis 2 (BRDT(2))
- Bromodomain-containing protein 4 (BRD4)
- Bromodomain-containing protein 4 (BRD4) (aa 44-168)
- MTI (35)
- Androgen receptor
- Baculoviral IAP repeat-containing protein 2/Estrogen receptor
- Cytochrome P450 19A1
- Estradiol receptor beta (ERβ)
- Estrogen receptor
- Estrogen-Related Receptor, gamma
- Estrogen-related receptor gamma
- Phospholipase D (PLD)
- Phospholipase D (PldA)
- Phospholipase D2 (PLD2)
- Progesterone receptor
- Steroid hormone receptor ERR2
- ubiquitin-conjugating enzyme E2 N
- 4-Hydroxytamoxifen
- 4-Hydroxytamoxifen (9)
- 4-[(1Z)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol
- AFIMOXIFENE
- CHEMBL489
- [3H]4-OHT
- cid_449459
- ADORA1
- Adenosine A1 receptor
- Adenosine A2 receptor
- Adenosine Receptors A2a (A2a)
- Adenosine receptor
- Adenosine receptor A1
- Adenosine receptor A1 (A1)
- Adenosine receptor A2a
- Adenosine receptor A2a and A3
- Adenosine receptor A2b
- Adenosine receptor A3
- Adenosine receptors; A2a & A2b
- Mu-type opioid receptor
- 1,3-dipropyl-8-cyclopentylxanthine
- 8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
- CHEMBL183
- DPCPX
- PD116948
- [3H]DPCPX
- Acetylcholinesterase
- Acyl-CoA: cholesterol acyltransferase (ACAT)
- Cholinesterases
- Dual Specificity Protein Phosphatase 1
- Dual specificity phosphatase Cdc25B
- Factor XIIa
- Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
- Human rhinovirus A protease
- Indoleamine 2,3-dioxygenase
- Leukocyte common antigen
- MKP-3
- Papain
- Protein-tyrosine phosphatase 1B
- 1,2-Dione-Based Compound, 8
- 1,2-dihydronaphthalene-1,2-dione
- 1,2-naphthoquinone
- CHEMBL52347
- cid_10667
- Acetylcholinesterase
- Cytochrome P450 3A
- HRH3
- Histamine H1 receptor
- Histamine H2 receptor
- Histamine H3 receptor
- Histamine H4 receptor
- Imidazoline I1
- Multidrug and toxin extrusion protein 1
- P-glycoprotein (P-gp)
- P-glycoprotein 1
- P-glycoprotein 1 and 3 (MDR1a/MDR1b)
- Potassium-transporting ATPase alpha chain 1/beta chain
- CHEMBL512
- Ranitidine
- ZANTAC
- dimethyl[(5-{[(2-{[(E)-1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}furan-2-yl)methyl]amine
- D(2) dopamine receptor
- D-Amino Acid Oxidase (DAAO)
- GABA A Alpha2Beta1Gamma2
- GABA A receptor alpha-3/beta-2/gamma-2
- GABA A receptor alpha-6/beta-2/gamma-2
- GABA B rho 1
- GABA receptor gamma-1 subunit
- GABA receptor rho-2 subunit
- GABA transporter
- GABA-C receptor
- Gamma-aminobutyric acid receptor subunit alpha-1
- Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A))
- Gamma-aminobutyric acid type B receptor subunit 1
- 5-(aminomethyl)-1,2-oxazol-3-ol
- Agarin
- CHEMBL273481
- Muscimol
- Pantherine
- Coagulation factor X
- Factor Xa (fXa)
- Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein
- Matriptase
- Plasma kallikrein
- Plasminogen
- Prothrombin
- Thrombin
- Tissue-type plasminogen activator
- Trypsin
- Tryptase
- Urokinase-type plasminogen activator
- Urokinase-type plasminogen activator/surface receptor
- 3-amidinophenylalanine deriv., 35
- CHEMBL107955
- ethyl 4-[(2S)-3-(3-carbamimidoylphenyl)-2-{[2,4,6-tris(propan-2-yl)benzene]sulfonamido}propanoyl]piperazine-1-carboxylate
- Cyclin-Dependent Kinase 1 (CDK1)
- Cyclin-Dependent Kinase 2 (CDK2)
- Cytoplasmic tyrosine-protein kinase BMX
- Hepatocyte growth factor receptor
- Homoserine kinase
- Mast/stem cell growth factor receptor Kit
- Polo-Like Kinase 1
- Polo-Like Kinase 3
- Serine/threonine-protein kinase Chk1/2
- Serine/threonine-protein kinase PLK3
- Tyrosine-protein kinase BRK
- Tyrosine-protein kinase BTK
- Tyrosine-protein kinase Fyn
- (2Z)-2-{[(2,5-dibromophenyl)amino](hydroxy)methylidene}-3-oxobutanenitrile
- CHEMBL228043
- LFM-A13
- Thr1 inhibitor, 2
- alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6
- Cytochrome P450 3A
- Nuclear receptor ROR-alpha
- Nuclear receptor ROR-beta
- Nuclear receptor ROR-gamma
- Nuclear receptor ROR-gamma (RORC)
- Nuclear receptor subfamily 1 group I member 2
- Oxysterols receptor LXR-alpha
- Oxysterols receptor LXR-beta
- US9458171, 95
- Carbonic Anhydrase III
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XIV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
13 Ki
- 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
- Diulo
- Metolazone
- Microx
- Zaroxolyn
- Carbonic Anhydrase III
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XIV
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 15
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
15 Ki
- 2,5-difluorophenol
- phenol derivative, 5
- Carbonic Anhydrase III
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XIV
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 15
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
17 Ki
- 3,5-difluorophenol
- phenol derivative, 6
- Carbonic Anhydrase III
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XIV
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 15
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
15 Ki
1 ΔG°
- 4-cyanophenol
- 4-hydroxybenzonitrile
- phenol derivative, 10
- Alpha carbonic anhydrase
- Astrosclerin-3
- Carbonic Anhydrase VA
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Gamma-carbonic anhydrase
43 Ki
2 ΔG°
- CHEMBL1644028
- SCN(-1)
- Thiocyanate
- cyanosulfanide
- sodium thiocyanate
- thiocyanate
- α-Carbonic anhydrase (αCA)
- β-Carbonic anhydrase (βCA)
- Alpha-carbonic anhydrase
- Astrosclerin-3
- Beta-carbonic anhydrase
- Carbonic Anhydrase VA
- Carbonic Anhydrase XV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 9
- Gamma-carbonic anhydrase
33 Ki
- CHEMBL1644029
- CHEMBL1644698
- CHEMBL186200
- NO3-
- nitrate ion
- nitrooxidane
- Human diphtheria toxin-like ADP-ribosyltransferase (ARTD3 or PARP3)
- Poly [ADP-ribose] polymerase 1
- Poly [ADP-ribose] polymerase 10
- Poly [ADP-ribose] polymerase 12
- Poly [ADP-ribose] polymerase 14
- Poly [ADP-ribose] polymerase 15
- Poly [ADP-ribose] polymerase 2
- Poly [ADP-ribose] polymerase 4
- Poly [ADP-ribose] polymerase tankyrase-1
- Poly [ADP-ribose] polymerase tankyrase-2
- Protein mono-ADP-ribosyltransferase PARP3
- Transient receptor potential cation channel subfamily M member 2
- poly-ADP-ribose polymerase 2 (PARP2)
- 2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide
- 2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin-2-yl)-acetamide
- CHEMBL372303
- N-(6-oxo-5,6-dihydro- phenanthridin-2-yl)-N,N-dimethylacetamide
- N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
- PJ34
- 1,3-beta-glucan synthase component GLS2
- ALK5
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6
- Cytochrome P450 3A
- Nuclear receptor subfamily 1 group I member 2
- Phosphodiesterase 4
- TGF-beta receptor type II
- TGF-beta receptor type-1
- TGF-betaR1 T204D
- 6-(4-(3-chloro-4-fluorophenyl)-1-(2-hydroxyethyl)-1H- imidazol-5-yl)imidazo[1,2-b]pyridazine-3-carbonitrile
- US10287295, Example 32'
- US9884868, Example 32'
- Adenosine deaminase
- Homo sapiens phosphodiesterase 2A (PDE2A)
- Phosphodiesterase 1
- Phosphodiesterase 11A (PDE11A)
- Phosphodiesterase 3
- Phosphodiesterase 8
- Phosphodiesterase 9A
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
- cAMP-specific 3',5'-cyclic phosphodiesterase 4A
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B
- cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform 1
- cAMP-specific 3',5'-cyclic phosphodiesterase 4D
- cGMP-specific 3',5'-cyclic phosphodiesterase
- (+)-EHNA
- (2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol
- CHEMBL296435
- Amine oxidase (flavin-containing) A
- Amine oxidase [flavin-containing] B
- LANA
- Monoamine Oxidase Type B (MAO-B)
- Monoamine oxidase
- Peroxisome proliferator-activated receptor
- Peroxisome proliferator-activated receptor alpha
- Peroxisome proliferator-activated receptor alpha (PPAR alpha)
- Peroxisome proliferator-activated receptor delta
- Peroxisome proliferator-activated receptor gamma
- Protein-tyrosine phosphatase 1B
- Retinoid receptor
- corticotropin releasing factor-binding protein
- 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione
- Avandia
- BRL 49653
- Brl-49653
- CHEMBL121
- ROSIGLITAZONE
- ROSIGLITAZONE MALEATE
- [3H]rosiglitazone
- cid_5281055
- rosiglitazone
- Cytoplasmic tyrosine-protein kinase BMX
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Fibroblast growth factor receptor 4
- Macrophage colony-stimulating factor 1 receptor (CSF1R)
- Pancreatic endoplasmic reticulum kinase (PERK)
- Serine/threonine-protein kinase TAO2
- Tyrosine-protein kinase Blk
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase Lyn
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor 3
- 8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
- US10294223, Cpd No. 6
- US9567334, Example 6
- US9815834, Compound 6
- BZLF2
- Dual Specificity Protein Phosphatase 1
- Dual specificity phosphatase Cdc25B
- Glyceraldehyde-3-phosphate dehydrogenase liver
- Heat Shock 70kDa Protein 1
- Hematopoietic protein-tyrosine phosphatase (HEPTP)
- Induced myeloid leukemia cell differentiation protein Mcl-1
- MKP-3
- X-linked inhibitor of apoptosis protein (XIAP)
- eukaryotic translation initiation factor 4 gamma, 1 isoform 4
- heat shock 70kDa protein 8 isoform 2
- large T antigen
- nuclear receptor subfamily 4, group A, member 1
22 IC50
- 8-carbethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
- 8-ethoxycarbonyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
- MLS-0025126.0001
- cid_2859888
- Alkaline phosphatase placental-like
- Alkaline phosphatase, tissue-nonspecific isozyme
- Alpi
- Apoptotic peptidase activating factor 1
- Beta-adrenergic receptor kinase 1
- Caspase-9
- DNA (cytosine-5)-methyltransferase 1 (DNMT1)
- Dual specificity protein phosphatase (VHR)
- Glyceraldehyde-3-phosphate dehydrogenase liver
- Hematopoietic protein-tyrosine phosphatase (HEPTP)
- Induced myeloid leukemia cell differentiation protein Mcl-1
- Intestinal alkaline phosphatase
- MKP-3
- 2-[5-[(Z)-(3-bromanyl-8-oxidanylidene-[1,3]thiazolo[4,5]imidazo[1,2-b]pyridin-7-ylidene)methyl]furan-2-yl]benzoic acid
- 2-[5-[(Z)-(3-bromo-8-keto-thiazolo[4,5]imidazo[1,2-b]pyridin-7-ylidene)methyl]-2-furyl]benzoic acid
- 2-[5-[(Z)-(3-bromo-8-oxo-7-thiazolo[4,5]imidazo[1,2-b]pyridinylidene)methyl]-2-furanyl]benzoic acid
- 2-[5-[(Z)-(3-bromo-8-oxo-[1,3]thiazolo[4,5]imidazo[1,2-b]pyridin-7-ylidene)methyl]furan-2-yl]benzoic acid
- MLS-0090801.0001
- cid_1357397
- Angiotensin II receptor
- Apelin receptor
- Apoptotic peptidase activating factor 1
- Caspase-3
- Caspase-9
- Heat shock protein HSP 90-alpha
- MPI protein
- PPP5C protein
- SUMO-1-specific protease
- SUMO/sentrin specific peptidase family member 8
- Trypanosoma brucei RNA editing ligase 1
- protein phosphatase 1, catalytic subunit, alpha isoform 3
- tyrosyl-DNA phosphodiesterase 2
14 IC50
- 1-butyl-2-(2-furoylamino)pyrrolo[3,2-b]quinoxaline-3-carboxylic acid ethyl ester
- 1-butyl-2-[[2-furanyl(oxo)methyl]amino]-3-pyrrolo[3,2-b]quinoxalinecarboxylic acid ethyl ester
- MLS000079916
- SMR000040037
- cid_659124
- ethyl 1-butyl-2-(furan-2-carbonylamino)pyrrolo[3,2-b]quinoxaline-3-carboxylate
- ethyl 1-butyl-2-(furan-2-ylcarbonylamino)pyrrolo[3,2-b]quinoxaline-3-carboxylate
- Apoptosis regulator Bcl-2
- BCL-W
- Bcl-2-related protein A1
- Cytochrome P450 2B6
- Cytochrome P450 3A
- DNA damage-inducible transcript 3 protein
- Glucose 6-phosphate dehydrogenase (G6PD)
- Induced myeloid leukemia cell differentiation protein Mcl-1
- Isoform Bcl-X(L)
- MPI protein
- XBP1
- eukaryotic translation initiation factor 4 gamma, 1 isoform 4
- glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
- (2E,5E)-2,5-bis(4-hydroxy-3,5-dimethoxy-benzylidene)cyclopentanone
- (2E,5E)-2,5-bis[(3,5-dimethoxy-4-oxidanyl-phenyl)methylidene]cyclopentan-1-one
- (2E,5E)-2,5-bis[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-1-cyclopentanone
- (2E,5E)-2,5-bis[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]cyclopentan-1-one
- CHEMBL498373
- MLS000374615
- SMR000244230
- cid_2407524
- Beta lactamase
- Beta-galactosidase
- Bfl-1
- C-C chemokine receptor type 6 (CCR6)
- G-protein coupled receptor 55
- Hepatocyte nuclear factor 4-alpha
- Serine/threonine-protein kinase RIPK2
- Tumor necrosis factor
- heat shock protein 90
- nucleotide-binding oligomerization domain containing 1
- nucleotide-binding oligomerization domain containing 2
- perilipin-1
- perilipin-5
- 3-(3,4-dimethoxyphenyl)-1-[(pentafluorophenyl)sulfonyl]-1H-pyrazol-5-amine
- 5-(3,4-dimethoxyphenyl)-2-(2,3,4,5,6-pentafluorophenyl)sulfonyl-3-pyrazolamine
- 5-(3,4-dimethoxyphenyl)-2-(2,3,4,5,6-pentafluorophenyl)sulfonylpyrazol-3-amine
- 5-(3,4-dimethoxyphenyl)-2-[2,3,4,5,6-pentakis(fluoranyl)phenyl]sulfonyl-pyrazol-3-amine
- MLS000045819
- SMR000028216
- [5-(3,4-dimethoxyphenyl)-2-(2,3,4,5,6-pentafluorophenyl)sulfonyl-pyrazol-3-yl]amine
- cid_3237441
- β-Carbonic anhydrase (CA1)
- Carbonic Anhydrase VA
- Carbonic anhydrase 1
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 9
- D-Aspartate Oxidase (DDO)
- D-amino-acid oxidase
- Metabotropic glutamate receptor 5
- Serine racemase
- Solute carrier family 22 member 20
- Solute carrier family 22 member 6
- beta-Carbonic Anhydrase
5 ΔG°
- SODIUM BENZOATE
- benzoate
- benzoic acid
- benzoic acid-d5
- PI3K-alpha/ Abl
- PI3K-alpha/ DNA-PK
- PI3K-alpha/ EGFR
- PI3K-alpha/ EphB4
- PI3K-alpha/ Hck
- PI3K-alpha/ PDGFR
- PI3K-alpha/ Src
- PI3K-alpha/ Src Mutant (T338I)
- PI3K-alpha/ VEGFR2
- PI3K-alpha/ mTOR
- PI3K-alpha/ p110-beta
- PI3K-alpha/ p110-delta
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
14 IC50
- 1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, PP494
- CID24905153
- DNA-PK/ Abl
- DNA-PK/ EGFR
- DNA-PK/ EphB4
- DNA-PK/ Hck
- DNA-PK/ PDGFR
- DNA-PK/ Src
- DNA-PK/ Src Mutant (T338I)
- DNA-PK/ VEGFR2
- DNA-PK/ p110-beta
- DNA-PK/ p110-delta
- DNA-dependent protein kinase
- PI3K-alpha/ DNA-PK
- mTOR/ DNA-PK
14 IC50
- 1-cyclopentyl-3-(H-imidazo[1,2-a]pyridin-7-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, PP162
- CID24905148
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6
- Cytochrome P450 3A
- Nuclear receptor ROR-alpha
- Nuclear receptor ROR-beta
- Nuclear receptor ROR-gamma
- Nuclear receptor ROR-gamma (RORC)
- Nuclear receptor subfamily 1 group I member 2
- Oxysterols receptor LXR-alpha
- Oxysterols receptor LXR-beta
- US10273259, Example 69
- US10711020, Example 69
- G protein signalling regulator 19
- Glucose 6-phosphate dehydrogenase (G6PD)
- MPI protein
- RGS7
- Regulator of G-protein signaling 8
- diphosphomevalonate decarboxylase
- glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
- mevalonate kinase
- neutrophil cytosolic factor 1
- phosphatase, orphan 1
- phosphomannomutase 2
- regulator of G-protein signaling 4
- regulator of G-protein signalling 16
- 2-(4-pyrrolidin-1-ylsulfonylphenyl)-1,2-benzothiazol-3-one
- 2-(4-pyrrolidinosulfonylphenyl)-1,2-benzothiazol-3-one
- 2-[4-(1-pyrrolidinylsulfonyl)phenyl]-1,2-benzothiazol-3-one
- MLS000055723
- SMR000060746
- cid_2325816
- Alkaline phosphatase placental-like
- Alkaline phosphatase, tissue-nonspecific isozyme
- Alpi
- G protein signalling regulator 19
- Intestinal alkaline phosphatase
- M18 aspartyl aminopeptidase
- Procathepsin L
- RGS7
- Regulator of G-protein signaling 8
- nuclear receptor subfamily 4, group A, member 1
- protein artemis isoform a
- regulator of G-protein signaling 4
- regulator of G-protein signalling 16
- 2-[2-oxidanylidene-2-[2-[(Z)-(3-oxidanyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]ethoxy]-N''-[(Z)-(3-oxidanyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]benzohydrazide
- MLS000540767
- N'-(3,4-dihydroxybenzylidene)-2-{2-[2-(3,4-dihydroxybenzylidene)hydrazino]-2-oxoethoxy}benzohydrazide
- N''-[(Z)-(3-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]-2-[2-[N''-[(E)-(3-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazino]-2-keto-ethoxy]benzohydrazide
- N''-[(Z)-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-2-[2-[[(Z)-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]hydrazo]-2-oxoethoxy]benzohydrazide
- N''-[(Z)-(3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-[2-[2-[(Z)-(3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-2-oxoethoxy]benzohydrazide
- N'-[(Z)-(3-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]-2-[2-[N'-[(E)-(3-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazino]-2-keto-ethoxy]benzohydrazide
- N'-[(Z)-(3-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]-2-[2-[N'-[(Z)-(3-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazino]-2-keto-ethoxy]benzohydrazide
- SMR000161891
- cid_11958779
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Multidrug resistance-associated protein 4
- Na,K-ATPase alpha1beta1
- Na,K-ATPase alpha2beta1
- Na,K-ATPase alpha2beta2
- Na,K-ATPase alpha2beta3
- Replicase polyprotein 1ab
- STAT3
- Sodium/potassium-transporting ATPase alpha-1 chain
- Solute carrier organic anion transporter family member 4C1
- Transcription Factor STAT1
- DIGITOXIN
- MLS000069787
- SMR000058529
- US10668094, Compound Digitoxin
- cid_441207
- Apoptotic peptidase activating factor 1
- Caspase-9
- DNA damage-inducible transcript 3 protein
- POsterior Segregation family member (pos-1)
- Phospholipase A2
- RecName: Full=Zinc finger protein mex-5
- Serine/threonine-protein kinase 33
- XBP1
- cysteine protease ATG4B isoform a
- eukaryotic translation initiation factor 4 gamma, 1 isoform 4
- neutrophil cytosolic factor 1
- streptokinase A precursor
- ubiquitin-conjugating enzyme E2 N
- 1-cetyl-3-methyl-imidazol-3-ium;bromide
- 1-hexadecyl-3-methyl-imidazol-3-ium;bromide
- 1-hexadecyl-3-methylimidazol-3-ium;bromide
- 3-hexadecyl-1-methyl-1H-imidazol-3-ium
- MLS000720114
- SMR000304643
- cid_2846928
- 3C-like proteinase (CVB3 3Cpro)
- Alkaline phosphatase placental-like
- Alkaline phosphatase, tissue-nonspecific isozyme
- Alpi
- Bile salt export pump
- Estradiol receptor beta (ERβ)
- Hexokinase-2
- Intestinal alkaline phosphatase
- POsterior Segregation family member (pos-1)
- RecName: Full=Zinc finger protein mex-5
- Replicase polyprotein 1ab
- SUMO1 activating enzyme subunit 1
- ubiquitin-conjugating enzyme E2I
- 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propionohydrazide;hydrochloride
- 2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydrochloride
- 2-azanyl-3-oxidanyl-N'-[[2,3,4-tris(oxidanyl)phenyl]methyl]propanehydrazide;hydrochloride
- BENSERAZIDE HYDROCHLORIDE
- Benserazide
- MLS000028424
- SMR000058421
- cid_26964
- 5-hydroxytryptamine receptor 2A
- Adenylate cyclase
- Alpha-2C adrenergic receptor
- D(1A) dopamine receptor
- D(1B) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Dopamine D1B
- Dopamine receptor
- POsterior Segregation family member (pos-1)
- RecName: Full=Zinc finger protein mex-5
- Replicase polyprotein 1ab
- adrenergic Alpha2
- (+/-)-SKF-38393
- 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
- 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)
- 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)
- 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)
- CHEMBL286080
- CHEMBL505308
- CHEMBL542700
- RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
- SK&F-38393
- SK-38393
- SKF 38393
- SKF-38393
- US9359372, SKF38393
- cid_147514
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- ADRA1B
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Alpha-1D adrenergic receptor
- Cerebral cortex alpha adrenergic receptor
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- DRD2
- Histamine H1 receptor
- Serotonin 2 (5-HT2) receptor
- 1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine
- 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine
- CHEMBL303313
- OCTOCLOTHEPIN-S
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- BZLF2
- Chain A, Crystal Structure Of The B1b2 Domains From Human Neuropilin- 1
- G-protein subunit alpha-16
- Kallikrein 7
- POsterior Segregation family member (pos-1)
- RecName: Full=Zinc finger protein mex-5
- Serotonin (5-HT) receptor
- Serotonin 1 (5-HT1) receptor
- Serotonin 2 (5-HT2) receptor
- trace amine-associated receptor 1
- (7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-9-yl)-methanol
- CHEMBL160976
- CHEMBL39947
- LYSERGOL
- cid_14987
- GRIA1
- GRIA2
- GRIA3
- GRIK1
- Glutamate receptor 1
- Glutamate receptor ionotropic AMPA
- Glutamate receptor ionotropic, AMPA
- Glutamate receptor ionotropic, AMPA 2
- Glutamate receptor ionotropic, AMPA 4
- Glutamate receptor ionotropic, kainate
- Glutamate receptor ionotropic, kainate 2
- Metabotropic glutamate receptor 1
- NMDA receptor subunit 2C (GluN2C)
- (R,S)-2-amino-3-(4-bromo-3-hydroxy-5-isoxazolyl)propionic acid
- 2-Amino-3-(4-bromo-3-hydroxy-isoxazol-5-yl)-propionic acid
- CHEMBL73698
- Sodium channel protein type I I alpha subunit
- Synaptic vesicular amine transporter
- Vesicular monoamine transporter 2 (VMAT P314G)
- Vesicular monoamine transporter 2 (VMAT P314L)
- Vesicular monoamine transporter 2 (VMAT P314T)
- Vesicular monoamine transporter 2 (VMAT V41A)
- Vesicular monoamine transporter 2 (VMAT V41F)
- Vesicular monoamine transporter 2 (VMAT V41I)
- Vesicular monoamine transporter 2 (VMAT2 G308A)
- Vesicular monoamine transporter 2 (VMAT2 G308P)
- Vesicular monoamine transporter 2 (VMAT2 V132A)
- Vesicular monoamine transporter 2 (VMAT2 V132G)
- Vesicular monoamine transporter 2 (VMAT2)
- 3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-pyrido[2,1-a]isoquinolin-2-one
- 3-isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one
- CHEMBL117785
- TETRABENAZINE
- Tetrabenazine (TBZ)
- 5-hydroxytryptamine receptor 7
- Adrenergic alpha1B
- Adrenergic receptor alpha
- Alpha adrenergic receptor 1A and 1B
- Alpha adrenergic receptor 1A and 1D
- Alpha-1A adrenergic receptor
- Alpha-1D adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- Sodium-dependent dopamine transporter
- Sodium-dependent noradrenaline transporter
- adrenergic Alpha1
- (+)2-Amino-1-phenyl-propan-1-ol
- (1R, 2R)-2-Amino-1-phenyl-propan-1-ol
- (1R, 2S)-2-Amino-1-phenyl-propan-1-ol
- (1S, 2R)-2-Amino-1-phenyl-propan-1-ol
- (1S, 2S)-2-Amino-1-phenyl-propan-1-ol
- 2-Amino-1-phenyl-propan-1-ol
- Biphetap
- Bromanate
- Bromatapp
- CHEMBL136560
- Codamine
- Contac
- Demazin
- Dimetane-DC
- Dimetapp
- Drize
- Hycomine
- Norephedrine, (+)
- Norephedrine, (-)
- Ornade
- PHENYLPROPANOLAMINE
- Pseudonorephedrine, (+) [cathine, (+)]
- Pseudonorephedrine, (-) [cathine, (-)]
- Tavist-D
- Triaminic-12
- 5-HT5
- 5-HT5B
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- Acetylcholinesterase
- HTR1F
- HTR6
- HTR7
- Serotonin (5-HT) receptor
- Serotonin 1B/1D receptor
- Serotonin 2 (5-HT2) receptor
- Sodium-dependent serotonin transporter
- 3-[2-(dimethylamino)ethyl]-1H-indol-5-ol
- 3-[2-(dimethylamino)ethyl]-5-indolol
- 3-[2-(dimethylamino)ethyl]indol-5-ol
- 3-[beta-(dimethylamino)ethyl]-5-hydroxyindole
- 5-hydroxy-N,N-dimethyltryptamine
- Bufotenin
- Bufotenine
- CHEMBL416526
- DM5-HT
- DMT,5-OH
- N,N-dimethylserotonin
- Coagulation factor IX
- Coagulation factor VII
- Coagulation factor X
- Coagulation factor XI
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Potassium voltage-gated channel subfamily H member 2
- Prothrombin
- Trypsin
13 IC50
- CHEMBL3330442
- Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Homo sapiens phosphodiesterase 2A (PDE2A)
- Phosphodiesterase 11A (PDE11A)
- Phosphodiesterase 7
- Phosphodiesterase 9A
- Phosphodiesterase Type 10 (PDE10A)
- cAMP-specific 3',5'-cyclic phosphodiesterase 4D
- cGMP-inhibited 3',5'-cyclic phosphodiesterase B
18 IC50
- CHEMBL3331521
- US9669035, B-1b
- Adrenergic receptor alpha
- Adrenergic receptor beta
- Alkaline phosphatase placental-like
- Alkaline phosphatase, tissue-nonspecific isozyme
- Alpi
- Dopamine receptor
- Intestinal alkaline phosphatase
- POsterior Segregation family member (pos-1)
- RecName: Full=Zinc finger protein mex-5
- TCRAV4S1
- Tyrosine-protein kinase ABL1
- lens epithelium-derived growth factor p75
- serum albumin precursor
- (1R)-1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol
- (R)-norlaudanosoline
- CHEMBL156383
- cid_440990
- Adrenaline alpha1
- Adrenaline alpha2
- Adrenergic Alpha
- Bile salt export pump
- Bile salt export pump (BSEP)
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Multidrug and toxin extrusion protein 1
- Multidrug and toxin extrusion protein 2
- Multidrug resistance-associated protein 4
- Potassium voltage-gated channel subfamily H member 2
- Solute carrier family 22 member 2
- Voltage-gated L-type calcium channel
- 4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
- CHEMBL517
- DISOPYRAMIDE
- alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide
- gamma-Diisopropylamino-alpha-phenyl-alpha-(2-pyridyl)butyramide
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- Adrenergic alpha1B
- Adrenergic receptor alpha-1
- Alpha adrenergic receptor 1A and 1B
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Alpha-1A adrenergic receptor
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Dopamine D1B
- Serotonin 1B/1D receptor
- Sigma non-opioid intracellular receptor 1
25 Ki
- (3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)phenyl)(piperidin-1-yl)methanone
- CHEMBL10085
- RWJ-377796
- mazapertine
- {3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450 3A
- Cytochrome P450 3A5 (CYP3A5)
- FK506-binding protein 1B
- Multidrug resistance-associated protein 4
- Nuclear receptor subfamily 1 group I member 2
- Peptidyl-prolyl cis-trans isomerase FKBP1A
- Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
- Peptidyl-prolyl cis-trans isomerase FKBP5
- Solute carrier organic anion transporter family member 1B1 (OATP1B1)
- calcineurin
- 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
- CHEMBL269732
- TACROLIMUS
- NR2B Channel Blocker
- Peroxisome Proliferator-Activated Receptor gamma/Retinoid X receptor alpha
- Peroxisome proliferator-activated receptor
- Peroxisome proliferator-activated receptor alpha
- Peroxisome proliferator-activated receptor gamma
- Retinoic acid receptor RXR-alpha
- Retinoic acid receptor alpha
- Retinoic acid receptor gamma
- Retinoid X receptor alpha
- Retinoid X receptor beta
- Retinoid X receptor gamma
- Retinoid X receptor gamma/retinoic acid receptor alpha
- Retinoid receptor
- 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID
- 6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopropyl]-nicotinic acid
- CHEMBL288436
- GABA B rho 1
- GABA receptor alpha-1/beta-3/gamma-2 subunit
- GABA receptor alpha-2/beta-2/gamma-2 subunit
- GABA receptor alpha-2/beta-3/gamma-2 subunit
- GABA receptor alpha-3/beta-2/gamma-2 subunit
- GABA receptor alpha-3/beta-3/gamma-2 subunit
- GABA receptor alpha-4/beta-3/gamma-2 subunit
- GABA receptor alpha-5/beta-3/gamma-2 subunit
- GABA receptor alpha-6/beta-3/gamma-2 subunit
- GABA-A receptor; alpha-1/beta-2/gamma-2
- GABA-B receptor 1/2
- GABA-C receptor
- Proton-coupled amino acid transporter 1
- 1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid
- 1,2,3,6-tetrahydropyridine-4-carboxylic acid
- 1,2,3,6-tetrahydropyridinium-4-carboxylate
- CHEMBL39071
- Isoguvacine
- ADRA1B
- Acetylcholinesterase
- Adrenergic Alpha
- Adrenergic alpha1B
- Alpha-1A adrenergic receptor
- Alpha-1D adrenergic receptor
- Bile salt export pump
- Calcium channel (Type L)
- Cerebral cortex alpha adrenergic receptor
- Potassium voltage-gated channel subfamily H member 2
- Sodium channel protein type 5 subunit alpha
- Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
- Voltage-gated potassium channel subunit Kv4.3
- ALFUZOSIN
- CHEMBL709
- N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Multidrug resistance-associated protein 4
- Serotonin 1d (5-HT1d) receptor
- Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
- Serotonin 3a (5-HT3a)/3b (5-HT3b)/3c (5-HT3c)/3d (5-HT3d)/3e (5-HT3e) receptor
- Uracil nucleotide/cysteinyl leukotriene receptor
- CHEMBL905
- MK 462 free base
- N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine
- N,N-dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine
- N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine
- RIZATRIPTAN
- risatriptan
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 3A
- 5-hydroxytryptamine receptor 4 (5-HT4)
- Adenosine receptor A2b
- Adrenergic receptor alpha-1
- D(2) dopamine receptor
- Histamine H1 receptor
- Muscarinic acetylcholine receptor M4
- Serotonin (5-HT) receptor
- Serotonin 2 (5-HT2) receptor
- 2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-tolyl-piperazin-1-yl)-ethanone
- CHEMBL120055
- CHEMBL321818
- GRM7
- GRM8
- Metabotropic glutamate receptor
- Metabotropic glutamate receptor 1
- Metabotropic glutamate receptor 2
- Metabotropic glutamate receptor 3
- Metabotropic glutamate receptor 4 (mGlu4)
- Metabotropic glutamate receptor 4 (mGluR4)
- Metabotropic glutamate receptor 5
- Metabotropic glutamate receptor 6
- Metabotropic glutamate receptor 6 (mGlu6)
- Metabotropic glutamate receptor 7 (mGlu7)
- Metabotropic glutamate receptor 8 (mGlu8)
- (1S,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanecarboxylic acid
- 2-(Amino-carboxy-methyl)-cyclopropanecarboxylic acid
- 2-(Amino-carboxy-methyl)-cyclopropanecarboxylic acid(2S,3S,4S-CCG)
- CHEMBL280563
- L-CCGI
- Adenosine A2 receptor
- Adenosine Receptors A2a (A2a)
- Adenosine receptor
- Adenosine receptor A1
- Adenosine receptor A2a
- Adenosine receptor A2a and A3
- Adenosine receptor A3
- Adenosine receptors; A2a & A2b
- Amine oxidase (flavin-containing) A
- Amine oxidase [flavin-containing] B
- Aryl hydrocarbon receptor
- Monoamine oxidase
- Nuclear receptor subfamily 1 group I member 2
- 8-(3-chlorostyryl)caffeine
- 8-[(E)-2-(3-chlorophenyl)ethenyl]-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione
- CHEMBL26138
- CSC
- cid_5353365
- Aldose reductase
- Angiotensin-converting enzyme
- Arachidonate 5-lipoxygenase
- Beta-secretase 1
- Cyclin-dependent kinase 2
- Cyclooxygenase
- Enoyl-ACP Reductase (FabI)
- Enoyl-acyl-carrier protein reductase
- Epidermal growth factor receptor
- Estradiol 17-beta-dehydrogenase 2
- Human immunodeficiency virus type 1 integrase
- Proto-oncogene tyrosine-protein kinase Src
- Xanthine dehydrogenase
- (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one (21)
- (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
- (E)-3-(3,4-Dihydroxy-phenyl)-1-(2,4-dihydroxy-phenyl)-propenone
- 3,4,2',4'-tetrahydroxychalone
- 3-(3,4-Dihydroxy-phenyl)-1-(2,4-dihydroxy-phenyl)-propenone
- Butein
- CHEMBL128000
- Acetylcholinesterase
- Bile salt export pump
- Bile salt export pump (BSEP)
- Butyrylcholinesterase (BuChE)
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- GluN1/GluN2B NMDA receptor
- Glutamate receptor ionotropic, NMDA 1
- Multidrug resistance-associated protein 4
- NMDA receptor subtype 2A protein (NR2A)
- NR1/NR2A
- Sigma non-opioid intracellular receptor 1
- Voltage-gated sodium channel subunit alpha Nav1.4 (Nav1.4)
- 2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone
- 2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone(Ketamine)
- CHEMBL742
- KETAMINE
- Ketalar
- Aurora kinase A/Targeting protein for Xklp2
- Aurora kinase B
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase PLK2
- Serine/threonine-protein kinase PLK3
- Serine/threonine-protein kinase PLK4
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
28 IC50
- CHEMBL3353347
- US10358436, Example A24
- US9907800, Example A24
- Aurora kinase A/Targeting protein for Xklp2
- Aurora kinase B
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase PLK2
- Serine/threonine-protein kinase PLK3
- Serine/threonine-protein kinase PLK4
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
15 IC50
- CHEMBL3353340
- US10358436, Example A22
- Aurora kinase A/Targeting protein for Xklp2
- Aurora kinase B
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Dual specificity protein kinase TTK
- Serine/threonine-protein kinase Chk2
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase PLK2
- Serine/threonine-protein kinase PLK3
- Serine/threonine-protein kinase PLK4
- CHEMBL3330410
- Calcium-independent phospholipase A2
- Group IID secretory phospholipase A2
- Group IIE secretory phospholipase A2
- Group IIF secretory phospholipase A2
- Group X secretory phospholipase A2
- Group XIIB secretory phospholipase A2-like protein
- Phospholipase A2
- Phospholipase A2 group 1B
- Phospholipase A2 group IIA
- Phospholipase A2 group V
- Phospholipase A2, major isoenzyme
- Phospholipase A2, membrane associated
- Secretory phospholipase A2, group V (sPLA2-V)
57 IC50
- (3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-acetic acid
- (3-Aminooxalyl-1-benzyl-2-ethyl-2,3-dihydro-1H-indol-4-yloxy)-acetic acid
- 2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
- CHEMBL148674
- Varespladib sodium
- BZLF2
- Ephrin type-B receptor 4
- Human immunodeficiency virus type 1 integrase
- Human immunodeficiency virus type 2 integrase
- Induced myeloid leukemia cell differentiation protein Mcl-1
- MPI protein
- Mitogen-activated protein kinase kinase kinase kinase 2
- POsterior Segregation family member (pos-1)
- RecName: Full=Zinc finger protein mex-5
- Tyrosine-protein kinase ABL1
- dTDP-4-dehydrorhamnose reductase
- eukaryotic translation initiation factor 4 gamma, 1 isoform 4
- lens epithelium-derived growth factor p75
- 2,6,7-Trihydroxy-9-methyl-xanthen-3-one
- CHEMBL175266
- NSC-66209
- cid_72721
- Acetylcholinesterase
- Acetylcholinesterase (AChE)
- Cholinergic, Nicotinic Alpha6
- Cholinergic, Nicotinic Alpha6Beta2
- Cholinergic, Nicotinic Alpha6Beta4
- Histamine H3 receptor
- Muscarinic acetylcholine receptor M2
- Neuronal acetylcholine receptor
- Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit
- Neuronal acetylcholine receptor subunit alpha-4
- Phospholipase B
- Sigma non-opioid intracellular receptor 1
- n-AChR
2 ΔG°
- 1,10-Bis(trimethyl ammonium)decane dibromide
- 1,10-bis-(trimethyl ammonium) decane dibromide
- CHEMBL1134
- DECAMETHONIUM
- DECAMETHONIUM BROMIDE
- Decamethonium Iodide
- N,N,N'',N''-Tetramethyl-decane-1,10-diammonium; dibromide
- N,N,N,N'',N'',N''-Hexamethyldecane-1,10-diammoniumdibromide
- Syncurine
- decane-1,10-bis(trimethylammonium bromide)
- Acetylcholine receptor
- Acetylcholine receptor protein alpha/beta/delta/gamma chain
- Cholinergic, Nicotinic Alpha3Beta2
- Neuronal acetylcholine receptor
- Neuronal acetylcholine receptor Alpha-4/Beta-2
- Neuronal acetylcholine receptor protein alpha-2 subunit/subunit beta-4
- Neuronal acetylcholine receptor protein alpha-3/beta-2 subunit
- Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit
- Neuronal acetylcholine receptor protein alpha-7 subunit
- Neuronal acetylcholine receptor subunit alpha-3
- Neuronal acetylcholine receptor subunit alpha-4
- Neuronal acetylcholine receptor; alpha2/beta2
- n-AChR
- (12R,13aR)-12-Methoxy-1,4,5,6,9,11,12,13-octahydro-8H-pyrano[4',3':3,4]pyrido[2,1-i]indol-2-one
- CHEMBL335712
- Dihydro-Beta-erythroidine
- Cannabinoid receptor
- Cannabinoid receptor 1
- Cannabinoid receptor 1 (CB1 D338A)
- Cannabinoid receptor 1 (CB1 H219A)
- Cannabinoid receptor 1 (CB1 I218A)
- Cannabinoid receptor 1 (CB1 I339A)
- Cannabinoid receptor 1 (CB1 L341A)
- Cannabinoid receptor 1 (CB1 P221A)
- Cannabinoid receptor 1 (CB1 R340A)
- Cannabinoid receptor 1 (CB1 T344A)
- Cannabinoid receptor 2
- Liver fatty acid binding protein (FABP1)
- N-arachidonyl glycine receptor
- 2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol
- 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxy-propyl)-cyclohexyl]-phenol
- 5-(1,1-Dimethyl-heptyl)-2-[(4R,6R)-5-hydroxy-2-((R)-3-hydroxy-propyl)-cyclohexyl]-phenol
- CHEMBL48552
- CP-55940
- CP-55940 [(-)-AC],XIV
- CP55,940
- CP55940
- ChEMBL_75020
- ATP-binding cassette sub-family G member 2
- Cytochrome P450 1A
- Cytochrome P450 2A6
- Cytochrome P450 2B6
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 2E1
- Cytochrome P450 3A
- Multidrug resistance protein 1/Multidrug resistance associated protein 1
- P-glycoprotein 1
- P-glycoprotein 1 and 3 (MDR1a/MDR1b)
- 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydro-2-isoquinolinyl)ethyl]phenyl}-4,5-dimethoxy-2-(3-quinolylcarboxamido)benzamide
- CHEMBL348475
- N-(2-((4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)carbamoyl)-4,5-dimethoxyphenyl)quinoline-3-carboxamide
- TARIQUIDAR
- ALK tyrosine kinase receptor
- Ephrin type-A receptor 2
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Hepatocyte growth factor receptor
- Histone deacetylase 1
- Insulin-like growth factor I receptor
- Macrophage-stimulating protein receptor
- Platelet-derived growth factor receptor beta
- Receptor protein-tyrosine kinase erbB-4
- Tyrosine-protein kinase receptor TYRO3
- Tyrosine-protein kinase receptor UFO
- Vascular endothelial growth factor receptor 1
15 IC50
- CHEMBL3417489
- 3C-like proteinase
- 3C-like proteinase (3CL-PRO)
- Alpha trans-inducing protein (VP16)
- COUP transcription factor 2 isoform a
- Eukaryotic initiation factor 4A-I
- FK506 binding protein 14
- FK506 binding protein 3
- FK506 binding protein 4
- Hypoxia inducible factors; HIF-1-alpha, HIF-2-alpha
- Peptidyl-prolyl cis-trans isomerase FKBP1A
- Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
- Peptidyl-prolyl cis-trans isomerase NIMA-interacting 2
- RPL19A
- 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide
- 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione
- CHEMBL123292
- Cycloheximid
- Zykloheximid
- cid_6197
- cycloheximide
- med.21724, Compound Cycloheximide
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Melanin-concentrating hormone receptor 2/HERG
- NK-3 receptor
- Neurokinin 1 receptor
- Neurokinin 2 receptor
- Neurokinin 3 receptor
- Neuromedin-K receptor
- Potassium voltage-gated channel subfamily H member 2
- Transcriptional regulator ERG
- CHEMBL3422010
- US10065961, Compound 1
- US10683295, Compound 1
- US9475814, 1
- BRAF/CRAF
- Casein kinase II subunit alpha
- Dual specificity tyrosine-phosphorylation-regulated kinase 4
- Kinesin-like protein KIF15
- Mixed lineage kinase 7
- Myocilin
- RAF proto-oncogene serine/threonine-protein kinase
- RAF serine/threonine protein kinase
- Receptor-interacting serine/threonine-protein kinase 3
- Serine/threonine-protein kinase B-raf
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase PLK4
- TGM2/ cRaf Kinase
- 3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-dihydro-indol-2-one
- 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one
- 3-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(Z)-ylidene]-5-iodo-1,3-dihydro-indol-2-one
- CHEMBL72365
- G6416 (GW5074)
- GW-5074
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytidine deaminase (CDA)
- Deoxynucleoside kinase
- Enoyl-[acyl-carrier-protein] reductase [NADH]
- MDM2-MDMX
- Multidrug resistance-associated protein 4
- Nuclear receptor coactivator 1
- Thymidine kinase
- Thymidine kinase, cytosolic
- Thymidine kinase, mitochondrial
- nuclear receptor coactivator 3 isoform a
- 1-beta-D-Arabinofuranosylcytosine
- 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
- 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
- CHEMBL803
- CYTARABINE
- 15-Lipoxygenase (LoxA)
- Angiopoietin-1 receptor
- Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
- Epidermal growth factor receptor
- Protein kinase C (PKC)
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase BTK
- Tyrosine-protein kinase CSK
- Tyrosine-protein kinase Fyn
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase ZAP-70
- Vascular endothelial growth factor receptor 2
25 IC50
- 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane
- 7-Cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
- CHEMBL47940
- NCGC00015280
- Carbonic Anhydrase VA
- Carbonic Anhydrase XIV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 13 (CA XIII)
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Carbonic anhydrases; II & IX
- Histone deacetylase
- CHEMBL3586274
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 4 (5-HT4)
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Adrenergic alpha1B
- D(2) dopamine receptor
- D(3) dopamine receptor
- Serotonin (5-HT) receptor
26 Ki
- 3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide
- 3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide
- 3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide (SB-258719)
- 4-Methyl-1-[(R)-3-methyl-4-(toluene-3-sulfonyl)-pentyl]-piperidine
- CHEMBL12264
- SB-258719
- Carbonic Anhydrase III
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XIV
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 15
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
13 Ki
- 2-Naphthalen-1-yl-1-(4-{[4-(2-piperidin-1-yl-ethylamino)-butylamino]-methyl}-piperidin-1-yl)-ethanone
- CHEMBL25101
- N-(3-(4-(3-aminopropylamino)butylamino)propyl)-2-(naphthalen-1-yl)acetamide
- N-{3-[4-(3-Amino-propylamino)-butylamino]-propyl}-2-naphthalen-1-yl-acetamide
- Bile salt export pump
- Calcium channel (Type L)
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 2J2
- Cytochrome P450 3A
- Multidrug resistance-associated protein 4
- Voltage-dependent L-type calcium channel subunit alpha-1C
- Voltage-gated calcium channel
16 IC50
- BAY-E-9736
- CHEBI:7575
- NIMODIPINE
- Nimodipine
- Nimotop
- 17-beta-hydroxysteroid dehydrogenase type 3
- Acetylcholinesterase
- Aldehyde dehydrogenase, mitochondrial
- Aldose reductase (AR)
- Axin-1/Glycogen synthase kinase-3 beta
- Butyrylcholinesterase (BuChE)
- Carbonic anhydrase
- Carbonic anhydrase 2
- Carbonic anhydrases; II & IX
- Hsf1 protein
- Non-structural protein 5B (NS5B)
- Sorbitol dehydrogenase
- Tyrosinase
- 7-Hydroxy-4-phenyl-chromen-2-one
- 7-hydroxy-4-phenyl-2H-chromen-2-one
- CHEMBL325841
- Coumarin derivative, 3c
- cid_5357479
- 72 kDa type IV collagenase
- ADAM17
- Collagenase 3
- Interstitial collagenase
- Matrix metalloproteinase 10
- Matrix metalloproteinase 15
- Matrix metalloproteinase 16
- Matrix metalloproteinase-12 (MMP12)
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-7 (MMP7)
- Matrix metalloproteinase-9
- Neutrophil collagenase
- Stromelysin-1
13 Ki
- 2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmethyl)-1-oxa-3,9-diaza-cyclopentadecane-8,12-dicarboxylic acid 12-hydroxyamide 8-[(2-oxo-2-piperazin-1-yl-ethyl)-amide]
- CHEMBL431680
- 72 kDa type IV collagenase
- ADAM17
- Collagenase 3
- Interstitial collagenase
- Matrix metalloproteinase 10
- Matrix metalloproteinase 15
- Matrix metalloproteinase 16
- Matrix metalloproteinase-12 (MMP12)
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-7 (MMP7)
- Matrix metalloproteinase-9
- Neutrophil collagenase
- Stromelysin-1
13 Ki
- 2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmethyl)-1-oxa-3,9-diaza-cyclopentadecane-8,12-dicarboxylic acid 8-carbamoylmethyl-amide 12-hydroxyamide
- CHEMBL115263
- 72 kDa type IV collagenase
- ADAM17
- Collagenase 3
- Interstitial collagenase
- Matrix metalloproteinase 10
- Matrix metalloproteinase 15
- Matrix metalloproteinase 16
- Matrix metalloproteinase-12 (MMP12)
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-7 (MMP7)
- Matrix metalloproteinase-9
- Neutrophil collagenase
- Stromelysin-1
30 Ki
- (8S,11R,12S)-2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmethyl)-1-oxa-3,9-diaza-cyclopentadecane-8,12-dicarboxylic acid 12-hydroxyamide 8-[(2-morpholin-4-yl-2-oxo-ethyl)-amide]
- (8S,11R,12S)-N12-hydroxy-N8-(2-morpholino-2-oxoethyl)-2,10-dioxo-11-((2'-(trifluoromethyl)biphenyl-4-yl)methyl)-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide
- 2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmethyl)-1-oxa-3,9-diaza-cyclopentadecane-8,12-dicarboxylic acid 12-hydroxyamide 8-[(2-morpholin-4-yl-2-oxo-ethyl)-amide]
- CHEMBL325163
- 72 kDa type IV collagenase
- ADAM17
- Collagenase 3
- Interstitial collagenase
- Matrix metalloproteinase 10
- Matrix metalloproteinase 15
- Matrix metalloproteinase 16
- Matrix metalloproteinase-12 (MMP12)
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-7 (MMP7)
- Matrix metalloproteinase-9
- Neutrophil collagenase
- Stromelysin-1
13 Ki
- 11-(3',5'-Bis-trifluoromethyl-biphenyl-4-ylmethyl)-2,10-dioxo-1-oxa-3,9-diaza-cyclopentadecane-8,12-dicarboxylic acid 12-hydroxyamide 8-[(2-oxo-2-piperazin-1-yl-ethyl)-amide]
- CHEMBL114878
- 5-hydroxytryptamine receptor 7
- Adrenergic receptor alpha-1
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- Delta-type opioid receptor
- Kappa-type opioid receptor
- Mu-type opioid receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Nociceptin receptor
- Voltage-gated L-type calcium channel
13 IC50
- 1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,3-dihydro-benzoimidazol-2-one
- CHEMBL114484
- Cereblon/Histone deacetylase 6
- Histone deacetylase
- Histone deacetylase 1
- Histone deacetylase 10
- Histone deacetylase 11
- Histone deacetylase 2
- Histone deacetylase 3
- Histone deacetylase 4
- Histone deacetylase 5
- Histone deacetylase 7
- Histone deacetylase 8
- Histone deacetylase 9
- Leukotriene A4 hydrolase
- CHEMBL1851943
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 4 (5-HT4)
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- D(1A) dopamine receptor
- D(2) dopamine receptor
- Histamine H1 receptor
- Serotonin (5-HT) receptor
- CHEMBL339980
- N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-yl]-4-fluoro-benzamide
- 5-hydroxytryptamine receptor 1A (5HT1A)
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 3A
- Alpha-2A adrenergic receptor
- D(2) dopamine receptor
- Dopamine D1 receptor
- Glycine receptor alpha-4 chain
- Histamine H1 receptor
- NMDA receptor subunit 2C (GluN2C)
- Neurokinin 1 receptor
- Neurokinin 2 receptor
- Neuromedin-K receptor
- Sigma non-opioid intracellular receptor 1
- 1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]-1-yl]-3-phenylpropane
- CHEMBL138458
- 5-hydroxytryptamine receptor 1A (5HT1A)
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 3A
- Alpha-2A adrenergic receptor
- D(2) dopamine receptor
- Dopamine D1 receptor
- Glycine receptor alpha-4 chain
- Histamine H1 receptor
- NMDA receptor subunit 2C (GluN2C)
- Neurokinin 1 receptor
- Neurokinin 2 receptor
- Neuromedin-K receptor
- Sigma non-opioid intracellular receptor 1
- 1'-benzyl-3-methoxy-3H-spiro[2-benzofuran-1,4'-piperidine]
- 1'-benzyl-3-methoxy-3H-spiro[isobenzofuran-1,4'-piperidine]
- 1'-benzyl-3-methoxyspiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]
- CHEMBL138809
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Melanin-concentrating hormone receptor 2/HERG
- Neurokinin 1 receptor
- Neurokinin 2 receptor
- Neurokinin 3 receptor
- Neuromedin-K receptor
- Neuromedin-K receptor (NK-3 receptor)
- Potassium voltage-gated channel subfamily H member 2
- hnk-3
- CHEMBL3608740
- US10030025, Compound 20
- US10836768, Cpd no 20
- US9422299, 20
- US9987274, Compound 20
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Melanin-concentrating hormone receptor 2/HERG
- Neurokinin 1 receptor
- Neurokinin 2 receptor
- Neurokinin 3 receptor
- Neuromedin-K receptor
- Neuromedin-K receptor (NK-3 receptor)
- Potassium voltage-gated channel subfamily H member 2
- hnk-3
- CHEMBL3608687
- US10030025, Compound 3
- US10836768, Cpd no 3
- US9422299, 3
- US9987274, Compound 3
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Melanin-concentrating hormone receptor 2/HERG
- Neurokinin 1 receptor
- Neurokinin 2 receptor
- Neurokinin 3 receptor
- Neuromedin-K receptor
- Neuromedin-K receptor (NK-3 receptor)
- Potassium voltage-gated channel subfamily H member 2
- hnk-3
- CHEMBL3608680
- US10030025, Compound 5
- US10836768, Cpd no 5
- US9422299, 5
- US9987274, Compound 5
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Melanin-concentrating hormone receptor 2/HERG
- Neurokinin 1 receptor
- Neurokinin 2 receptor
- Neurokinin 3 receptor
- Neuromedin-K receptor
- Neuromedin-K receptor (NK-3 receptor)
- Potassium voltage-gated channel subfamily H member 2
- hnk-3
- CHEMBL3608741
- US10030025, Compound 11
- US10836768, Cpd no 11
- US9422299, 11
- US9987274, Compound 11
- Dual specificity mitogen-activated protein kinase kinase 1
- Dual specificity mitogen-activated protein kinase kinase 3
- Dual specificity mitogen-activated protein kinase kinase 6
- Epidermal growth factor receptor
- Macrophage colony-stimulating factor 1 receptor (CSF1R)
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 8
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
15 IC50
- 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-cyano-phenyl)-amide
- CHEMBL106966
- P2X purinoceptor 1
- P2X purinoceptor 2
- P2X purinoceptor 3
- P2X purinoceptor 4
- P2X purinoceptor 5
- P2X purinoceptor 6
- P2Y purinoceptor 1
- Purinergic receptor P2Y1
- Purinergic receptor P2Y11
- Purinergic receptor P2Y12
- Purinergic, P2X2
- Pyrimidinergic receptor P2Y6
- S-adenosylmethionine synthetase (MAT 1 and MAT 2)
- 2-MeSATP
- ATP, 2-meS
- CHEMBL336208
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- Adenosine A1 receptor
- Adenosine A2a receptor
- Adenosine Receptors A2a (A2a)
- Adenosine receptor A1
- Adenosine receptor A2a
- Adenosine receptor A2a and A3
- Adenosine receptor A2b
- Adenosine receptor A3
- Adenosine receptors; A2a & A2b
- Equilibrative nucleoside transporter 1
- (2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide
- (2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide
- (2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide
- (3R,4S,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide
- (3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide
- (N-6-(3-iodobenzyl)adenosine-5'-N-methyluronamide
- 3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide
- CHEMBL119709
- IB-MECA
- N6-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine
- Dual specificity mitogen-activated protein kinase kinase 1
- Dual specificity mitogen-activated protein kinase kinase 6
- Epidermal growth factor receptor
- Macrophage colony-stimulating factor 1 receptor (CSF1R)
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 8
- PDGFR-beta/Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase ABL
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
15 IC50
- 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carbothioic acid (benzo[1,3]dioxol-5-ylmethyl)-amide
- 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carbothioic acid (benzo[1,3]dioxol-5-ylmethyl)-amide(KN734)
- CHEMBL102301
- Dual specificity mitogen-activated protein kinase kinase 1
- Dual specificity mitogen-activated protein kinase kinase 3
- Dual specificity mitogen-activated protein kinase kinase 6
- Epidermal growth factor receptor
- Macrophage colony-stimulating factor 1 receptor (CSF1R)
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 8
- PDGFR-beta/Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
14 IC50
- 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carbothioic acid benzylamide
- CHEMBL319894
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- D(1A) dopamine receptor
- D(1B) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- Dopamine D1 receptor
- Dopamine D1B
- Dopamine receptor
- CHEMBL25236
- CHEMBL540612
- N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide
- Naphthalene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- ADRA1B
- Alpha-1D adrenergic receptor
- Cerebral cortex alpha adrenergic receptor
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- Histamine H1 receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
21 Ki
- 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
- CHEMBL319352
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Adrenergic receptor alpha-2
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- Histamine H1 receptor
- Sodium-dependent serotonin transporter
15 Ki
- 2-(4-(4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)butyl)isoindoline-1,3-dione
- 2-{4-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-isoindole-1,3-dione
- CHEMBL131495
- SLV-310
- Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
- Homo sapiens phosphodiesterase 2A (PDE2A)
- Phosphodiesterase 11A (PDE11A)
- Phosphodiesterase 4
- Phosphodiesterase 6C (PDE6C)
- Phosphodiesterase 7
- Phosphodiesterase 8
- Phosphodiesterase 9A
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B
- cAMP-specific 3',5'-cyclic phosphodiesterase 4D
- cGMP-inhibited 3',5'-cyclic phosphodiesterase B
- cGMP-specific 3',5'-cyclic phosphodiesterase
13 IC50
- CHEMBL3628685
- 5-HT5
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 5A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- 5-hydroxytryptamine receptor 7 (5HT7)
- D(2) dopamine receptor
- DRD1
- HTR6
- Serotonin (5-HT) receptor
- Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
25 Ki
- (6aR,9R)-5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid diethylamide
- 5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid diethylamide
- CHEMBL274384
- LSD,2-Bromo
- Arachidonate 5-lipoxygenase
- Aurora kinase A/Targeting protein for Xklp2
- Aurora kinase B
- Axin-1/Glycogen synthase kinase-3 beta
- CDK2/CycE
- Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
- Cyclin-Dependent Kinase 5 (CDK5)
- Cyclin-Dependent Kinase 9 (CDK9)
- Cyclin-dependent kinase 1
- Cyclin-dependent kinase 5 regulatory subunit 1
- Protein kinase Pfmrk
- Serine/threonine-protein kinase Aurora-C
- Voltage-gated calcium channel subunit alpha Cav2.2
- (Z)-1H,1''H-[2,3'']Biindolylidene-3,2''-dione 3-oxime
- (Z)-1H,1'H-[2,3']Biindolylidene-3,2'-dione 3-oxime
- 1H,1''H-[2,3'']Biindolylidene-3,2''-dione 3-oxime
- 1H,1'H-[2,3']Biindolylidene-3,2'-dione 3-oxime
- 3-(3-(hydroxyimino)indolin-2-ylidene)indolin-2-one
- CHEMBL126077
- Cytochrome P450 1A
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- GRM7
- GRM8
- Metabotropic glutamate receptor
- Metabotropic glutamate receptor 1
- Metabotropic glutamate receptor 2
- Metabotropic glutamate receptor 3
- Metabotropic glutamate receptor 4 (mGluR4)
- Metabotropic glutamate receptor 5
- Metabotropic glutamate receptor 6
- CHEMBL3633943
- Acetylcholinesterase
- Cyclooxygenase
- Fatty acid binding protein muscle
- Fatty acid-binding protein 4 (FABP4)
- Fatty acid-binding protein 5 (FABP5)
- Fatty acid-binding protein 5 (FABP5)(DSm)
- Fatty acid-binding protein 5 (FABP5)(NLSm)
- Intestinal fatty acid-binding protein (hIFABP)
- Peroxisome proliferator-activated receptor
- Prostaglandin G/H synthase (Cyclooxygenase-2)
- Protein-tyrosine phosphatase 1B
- Toll-like receptor 2 (TLR2)
- Vanilloid receptor
- 1-HEXYLDECANOIC ACID
- CHEMBL82293
- Hexadecanoic acid
- Hexadecanoic acid anion
- Palmitic acid (PA)
- Alpha-chymotrypsin
- Arachidonate 5-lipoxygenase
- Cyclin-dependent kinase 2
- Dihydroorotate Dehydrogenase (DHODH)
- Dihydroorotate dehydrogenase
- Inositol hexakisphosphate kinase 2
- Inositol polyphosphate multikinase
- Leucine aminopeptidase (LAP)
- Lipoxygenase-1
- Poly [ADP-ribose] polymerase 1
- Poly [ADP-ribose] polymerase tankyrase-1
- Poly [ADP-ribose] polymerase tankyrase-2
- Telomerase reverse transcriptase
- 2-(3,4-dihydroxyphenyl)-4H-chromen-4-one
- 3',4'-dihydroxy flavone
- 3',4'-dihydroxyflavone
- CHEMBL222556
- Bromodomain adjacent to zinc finger domain protein 2A
- Bromodomain adjacent to zinc finger domain protein 2B
- Bromodomain and PHD finger-containing protein 3
- Bromodomain and WD repeat-containing protein 1
- Bromodomain testis-specific protein
- Bromodomain-containing protein 1
- Bromodomain-containing protein 2
- Bromodomain-containing protein 3
- Bromodomain-containing protein 4
- CREB-binding protein
- E3 ubiquitin-protein ligase TRIM33
- Protein polybromo-1
- Transcription intermediary factor 1-alpha
- CHEMBL3786012
- 72 kDa type IV collagenase
- Collagenase 3
- Disintegrin and metalloproteinase domain-containing protein 17
- Interstitial collagenase
- Matrix metalloproteinase 16
- Matrix metalloproteinase-12 (MMP12)
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-7 (MMP7)
- Matrix metalloproteinase-9
- Neutrophil collagenase
- Pseudolysin
- Stromelysin-1
- Thermolysin
24 IC50
- (R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydroxy-3-methyl-butyramide
- (R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
- CHEMBL179288
- Carbonic Anhydrase III
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XIV
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 15
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
16 Ki
- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylsulfamide
- CHEMBL190447
- N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]aminosulfonamide
- N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfamide
- Bcr-Abl
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Fibroblast growth factor receptor 2
- MAP kinase-interacting serine/threonine-protein kinase 1
- MAP kinase-interacting serine/threonine-protein kinase 2
- Mast/stem cell growth factor receptor Kit
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
13 IC50
- CHEMBL3806189
- Bcr-Abl
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Fibroblast growth factor receptor 2
- MAP kinase-interacting serine/threonine-protein kinase 1
- MAP kinase-interacting serine/threonine-protein kinase 2
- Mast/stem cell growth factor receptor Kit
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
13 IC50
- CHEMBL3805771
- Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
- Ephrin type-B receptor 3 (EPHB3)
- Epidermal growth factor receptor
- Fibroblast growth factor receptor
- Mitogen-activated protein kinase 1
- PDGFR-beta/Platelet-derived growth factor receptor alpha
- Protein kinase C alpha type
- Protein kinase C delta type
- RAC-alpha serine/threonine-protein kinase
- Serine/threonine-protein kinase Sgk1
- Tyrosine-protein kinase Fyn
- Vascular endothelial growth factor receptor 2
- cAMP-dependent protein kinase (PKA)
13 IC50
- 7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclopentyl)-3-(4-methoxyphenyl)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one