Found 43 with Last Name = 'kasprzyk' and Initial = 'r' 
Affinity DataKi: 410nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: 680nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: 730nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: 870nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: 870nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: 9.30E+3nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: 9.68E+3nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: 9.68E+3nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: 1.38E+4nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human DcpS using pyrene labeled 7-methylguanosine triphosphate as substrate preincubated for 15 mins followed by enzyme addition by flu...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 3.82E+5nMAssay Description:Inhibition of eIF4E (unknown origin)More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Oryctolagus cuniculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of eIF4E in rabbit reticulocyte lysate system assessed as reduction in ARCA mRNA cap-dependent translation measured after 60 mins by lucif...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Oryctolagus cuniculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of eIF4E in rabbit reticulocyte lysate system assessed as reduction in ARCA mRNA cap-dependent translation measured after 60 mins by lucif...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Oryctolagus cuniculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of eIF4E in rabbit reticulocyte lysate system assessed as reduction in ARCA mRNA cap-dependent translation measured after 60 mins by lucif...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human DCPS using m7GMPF as substrate after 30 mins by nucleoside 5'-fluorophosphate probe based HTS assayMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Oryctolagus cuniculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of eIF4E in rabbit reticulocyte lysate system assessed as reduction in ARCA mRNA cap-dependent translation measured after 60 mins by lucif...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Oryctolagus cuniculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of eIF4E in rabbit reticulocyte lysate system assessed as reduction in ARCA mRNA cap-dependent translation measured after 60 mins by lucif...More data for this Ligand-Target Pair
3D Structure (crystal)TargetEukaryotic translation initiation factor 4E(Oryctolagus cuniculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of eIF4E in rabbit reticulocyte lysate system assessed as reduction in ARCA mRNA cap-dependent translation measured after 60 mins by lucif...More data for this Ligand-Target Pair
Affinity DataIC50: 4.22E+4nMAssay Description:Inhibition of human DCPS using m7GMPF as substrate after 30 mins by nucleoside 5'-fluorophosphate probe based HTS assayMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Oryctolagus cuniculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of eIF4E in rabbit reticulocyte lysate system assessed as reduction in ARCA mRNA cap-dependent translation measured after 60 mins by lucif...More data for this Ligand-Target Pair
Target7-methylguanosine phosphate-specific 5'-nucleotidase(Homo sapiens)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataIC50: 8.78E+4nMAssay Description:Inhibition of recombinant His6/SUMO-tagged human cN3B (1 to 300 residues) expressed in Escherichia coli BL21(DE3) RIL assessed as reduction in dephos...More data for this Ligand-Target Pair
Target7-methylguanosine phosphate-specific 5'-nucleotidase(Homo sapiens)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of recombinant His6/SUMO-tagged human cN3B (1 to 300 residues) expressed in Escherichia coli BL21(DE3) RIL assessed as reduction in dephos...More data for this Ligand-Target Pair
Affinity DataIC50: 2.44E+5nMAssay Description:Inhibition of human DCPS using m7GMPF as substrate after 30 mins by nucleoside 5'-fluorophosphate probe based HTS assayMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 70nMAssay Description:Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 230nMAssay Description:Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 570nMAssay Description:Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 49nMAssay Description:Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 17.7nMAssay Description:Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 18nMAssay Description:Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 344nMAssay Description:Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 302nMAssay Description:Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 1.24E+3nMAssay Description:Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 460nMAssay Description:Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 2.00E+3nMAssay Description:Inhibition of fluorescein-labeled m7GDPC4H5 binding to mouse eIF4E (28 to 217 residues) by MST methodMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 5.90E+3nMAssay Description:Inhibition of fluorescein-labeled m7GDPC4H5 binding to mouse eIF4E (28 to 217 residues) by MST methodMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Warsaw
Curated by ChEMBL
University Of Warsaw
Curated by ChEMBL
Affinity DataKd: 230nMAssay Description:Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...More data for this Ligand-Target Pair
