Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 0.0316nMAssay Description:Binding affinity to 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 3.98nMAssay Description:Binding affinity to 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 7.70nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Binding affinity to 5HT4R (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 67nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 106nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 127nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 132nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 141nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 154nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 178nMAssay Description:Displacement of [3H]granisetron from 5HT3 receptor in Wistar rat cortical membranes by liquid scintillation spectrometeryMore data for this Ligand-Target Pair
Affinity DataKi: 283nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 344nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 563nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 0.830nMAssay Description:Antagonist activity at human wild type 5-HT3A receptor expressed in HEK293 cells assessed as inhibition of 5-HT-induced response after 45 mins by FLI...More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Antagonist activity at human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells assessed as inhibition of 5-HT-induced response after 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Partial agonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as effect on serotonin-induced receptor/Gbeta1 coupling...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Partial agonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as effect on serotonin-induced receptor/Gbeta1 coupling...More data for this Ligand-Target Pair
Affinity DataIC50: 203nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
Affinity DataIC50: 453nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
Affinity DataIC50: 916nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Binding affinity to human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKd: 0.530nMAssay Description:Binding affinity to human wild type 5-HT3A receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.180nMAssay Description:Binding affinity to human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKd: 0.320nMAssay Description:Binding affinity to human wild type 5-HT3A receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Agonist activity at human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataEC50: 320nMAssay Description:Agonist activity at human wild type 5-HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair