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Found 4370 with Last Name = 'morgan' and Initial = 'd'
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220746(CHEMBL292189)
Affinity DataKi:  0.0398nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220747(CHEMBL56863)
Affinity DataKi:  0.0631nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408198(CHEMBL91278)
Affinity DataKi:  0.0794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50060964((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...)
Affinity DataKi:  0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408201(CHEMBL88512)
Affinity DataKi:  0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062051(1-Dimethylcarbamoyl-6-(4-fluoro-phenyl)-3-[4-(2-me...)
Affinity DataKi:  0.150nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220750(CHEMBL55695)
Affinity DataKi:  0.158nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062066(3-[4-(2-Methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-b...)
Affinity DataKi:  0.190nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50160161(5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-pheny...)
Affinity DataKi:  0.251nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220788(CHEMBL417954)
Affinity DataKi:  0.251nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220744(CHEMBL55290)
Affinity DataKi:  0.316nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408248(CHEMBL330060)
Affinity DataKi:  0.398nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408246(CHEMBL92261)
Affinity DataKi:  0.398nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50048485((S)-4-Methyl-2-{methyl-[4-(2-methyl-imidazo[4,5-c]...)
Affinity DataKi:  0.400nMAssay Description:The compound was evaluated for its binding affinity against PAF receptor in rabbit plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50048485((S)-4-Methyl-2-{methyl-[4-(2-methyl-imidazo[4,5-c]...)
Affinity DataKi:  0.400nMAssay Description:The compound was evaluated for its binding affinity against PAF receptor in rabbit plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220785(CHEMBL293149)
Affinity DataKi:  0.501nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50033112(6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyla...)
Affinity DataKi:  0.501nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062069(4-Methoxy-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-y...)
Affinity DataKi:  0.510nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062101(4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...)
Affinity DataKi:  0.630nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062056(1-Dimethylcarbamoyl-3-{2-[4-(2-methyl-imidazo[4,5-...)
Affinity DataKi:  0.630nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062061(1-(3,3-Dimethyl-2-oxo-butyl)-3-[4-(2-methyl-imidaz...)
Affinity DataKi:  0.670nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062045(6-Benzofuran-2-yl-1-dimethylcarbamoyl-3-[4-(2-meth...)
Affinity DataKi:  0.780nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408244(CHEMBL93736)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50160165(CHEMBL88272 | RS-17053 | [2-(2-Cyclopropylmethoxy-...)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408242(CHEMBL91876)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM31046(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408232(CHEMBL91093)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408229(CHEMBL329160)
Affinity DataKi:  0.794nMAssay Description:The compound was screened in vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220782(CHEMBL53675)
Affinity DataKi:  0.794nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220786(CHEMBL55629)
Affinity DataKi:  0.794nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408205(CHEMBL88435)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062082(4-Methyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...)
Affinity DataKi:  0.820nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062113(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Affinity DataKi:  0.850nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062064(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Affinity DataKi:  0.860nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062092((4,7-Dimethyl-1H-indol-3-yl)-[4-(2-methyl-imidazo[...)
Affinity DataKi:  0.870nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062106(4-Chloro-3-[4-(2-methyl-imidazo[4,5-b]pyridin-1-yl...)
Affinity DataKi:  0.900nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062118(4-Ethyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylm...)
Affinity DataKi:  0.910nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062048(1-Dimethylcarbamoyl-3-[4-(2-methyl-benzoimidazol-1...)
Affinity DataKi:  0.920nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062098(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Affinity DataKi:  0.950nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062054(4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...)
Affinity DataKi:  1nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062054(4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...)
Affinity DataKi:  1nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220748(CHEMBL59153)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220779(CHEMBL298838)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062091(1-(2-Ethoxy-ethyl)-3-[4-(2-methyl-imidazo[4,5-c]py...)
Affinity DataKi:  1.10nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062058(6-(4-Fluoro-phenyl)-3-[4-(2-methyl-imidazo[4,5-c]p...)
Affinity DataKi:  1.20nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062084(4-Ethynyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-y...)
Affinity DataKi:  1.30nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50160152(3-(3-{3-[4-Fluoro-2-(2,2,2-trifluoro-ethoxy)-pheny...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50206243(CHEMBL3918431)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in HEK293 cell membranes incubated for 2 hrs and measured by gamma countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062110(1-Isopropyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1...)
Affinity DataKi:  1.30nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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