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Found 35 with Last Name = 'nakai' and Initial = 'd'
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50579915(CHEMBL4442570)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of CDK8 in human HEK293 cells measured by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50579909(CHEMBL5076378)
Affinity DataIC50:  31nMAssay Description:Inhibition of CDK8 in human HEK293 cells measured by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM576465(US11471446, Compound DBA-6)
Affinity DataIC50:  31nMAssay Description:Inhibition of CDK8 in human HEK293 cells measured by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50579914(CHEMBL5071605)
Affinity DataIC50:  33nMAssay Description:Inhibition of CDK8 in human HEK293 cells measured by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50579911(CHEMBL5090279)
Affinity DataIC50:  33nMAssay Description:Inhibition of CDK8 in human HEK293 cells measured by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50579912(CHEMBL5083027)
Affinity DataIC50:  34nMAssay Description:Inhibition of CDK8 in human HEK293 cells measured by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 2B1(Rattus norvegicus)
Tohoku University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50101853((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...)
Affinity DataIC50:  36nMAssay Description:TP_TRANSPORTER: inhibition of PGD2 uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50579910(CHEMBL5078832)
Affinity DataIC50:  93nMAssay Description:Inhibition of CDK8 in human HEK293 cells measured by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50579907(CHEMBL2348334)
Affinity DataIC50:  130nMAssay Description:Inhibition of CDK8 in human HEK293 cells measured by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 2B1(Rattus norvegicus)
Tohoku University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataIC50:  287nMAssay Description:TP_TRANSPORTER: inhibition of PGD2 uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50579913(CHEMBL5088336)
Affinity DataIC50:  410nMAssay Description:Inhibition of CDK8 in human HEK293 cells measured by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50579908(CHEMBL5093576)
Affinity DataIC50:  520nMAssay Description:Inhibition of CDK8 in human HEK293 cells measured by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM50115195(CHEMBL3609361)
Affinity DataEC50:  540nMAssay Description:Agonist activity at human LXRalpha expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human LXRalpha expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubate...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50363937(CHEMBL1951588)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM23165(CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50363937(CHEMBL1951588)
Affinity DataEC50:  350nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human S1P4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human S1P5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM23165(CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...)
Affinity DataEC50:  0.290nMAssay Description:Agonist activity at rat S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50363937(CHEMBL1951588)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at rat S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50364607(CHEMBL1951304)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at rat S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM23165(CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...)
Affinity DataEC50:  0.370nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM50115191(CHEMBL3609573)
Affinity DataEC50:  510nMAssay Description:Agonist activity at human LXRalpha expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubate...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human LXRbeta expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubated...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM50115195(CHEMBL3609361)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human LXRbeta expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM50115194(CHEMBL3609362)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human LXRbeta expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM50115193(CHEMBL3609363)
Affinity DataEC50:  260nMAssay Description:Agonist activity at human LXRbeta expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM50115192(CHEMBL3609572)
Affinity DataEC50:  530nMAssay Description:Agonist activity at human LXRbeta expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM50115191(CHEMBL3609573)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human LXRbeta expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM50115192(CHEMBL3609572)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human LXRalpha expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM50115193(CHEMBL3609363)
Affinity DataEC50:  280nMAssay Description:Agonist activity at human LXRalpha expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Daiichi Sankyo Rd Novare

Curated by ChEMBL
LigandPNGBDBM50115194(CHEMBL3609362)
Affinity DataEC50:  310nMAssay Description:Agonist activity at human LXRalpha expressed in African green monkey kidney CV1 cells co-expressing pTAL-LXRE including LXR response element incubate...More data for this Ligand-Target Pair