Compile Data Set for Download or QSAR
maximum 50k data
Found 184 with Last Name = 'ostresh' and Initial = 'jm'
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50369460(CHEMBL1788109)
Affinity DataKi:  0.160nMAssay Description:Enzyme inhibitory activity towards Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071508((2S,3S)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-diox...)
Affinity DataKi:  62nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071501((R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...)
Affinity DataKi:  64nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071501((R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...)
Affinity DataKi:  80nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071506((2R,3R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-diox...)
Affinity DataKi:  125nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071504((R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...)
Affinity DataKi:  189nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071510((S)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...)
Affinity DataKi:  254nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071502((2R,3S)-2-[(R)-4-(3-Amino-propyl)-3-benzyl-2,5-dio...)
Affinity DataKi:  333nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071511((R)-2-[(S)-4-(3-Amino-propyl)-3-benzyl-2,5-dioxo-i...)
Affinity DataKi:  406nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071509((R)-2-[(R)-4-(3-Amino-propyl)-3-benzyl-2,5-dioxo-i...)
Affinity DataKi:  435nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071500((R)-2-[(R)-4-(5-Amino-pentyl)-3-benzyl-2,5-dioxo-i...)
Affinity DataKi:  2.42E+3nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071503((R)-2-[(R)-4-(5-Amino-pentyl)-3-benzyl-2,5-dioxo-i...)
Affinity DataKi:  3.63E+3nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071507((2R,3S)-2-[(R)-4-(5-Amino-pentyl)-3-benzyl-2,5-dio...)
Affinity DataKi:  4.62E+3nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188149(4-[(2S)-2-(dimethylamino)-3-{[(2S)-1-(4-hydroxyphe...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188156(4-[(2S)-3-{[(2S)-1-(4-hydroxyphenyl)-3-{methyl[(2S...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity against mu opioid receptor in guinea-pig ileum assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188168(4-[(2S)-3-{[(2S)-1-(benzylamino)-3-(4-hydroxypheny...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188167(4-[(2S)-2-amino-3-{[(2S)-1-{[(2S)-1-[(2S)-2-(amino...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity against mu opioid receptor in guinea-pig ileum assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188203(4-[(2S)-2-(dimethylamino)-3-{[(2S)-1-(4-hydroxyphe...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity against mu opioid receptor in guinea-pig ileum assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188209(4-[(2S)-2-amino-3-{[(2S)-1-(benzylamino)-3-(4-hydr...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188217(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-(aminomethyl)p...)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188210(4-[(2S)-2-amino-3-{[(2S)-1-(4-hydroxyphenyl)-3-{me...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity against mu opioid receptor in guinea-pig ileum assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188195(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S,3R)-1-{...)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM36187(1-methylhexylamine | Tuaminoheptane)
Affinity DataIC50:  14nMAssay Description:Antagonistic activity towards Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188202(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S,3R)-1-[...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188211(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S)-1-[(2S...)
Affinity DataIC50:  18nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188186(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S,3R)-1-{...)
Affinity DataIC50:  19nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188194(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S,3R)-1-{...)
Affinity DataIC50:  19nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188215(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S,3R)-1-{...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188212(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S)-1-amin...)
Affinity DataIC50:  24nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188200(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S)-1-{[(2...)
Affinity DataIC50:  27nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188184(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S)-1-{[(2...)
Affinity DataIC50:  27nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188173(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S,3R)-1-{...)
Affinity DataIC50:  32nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188214(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S)-1-{[(2...)
Affinity DataIC50:  34nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188157(4-[(2S)-2-amino-3-{[(2S)-1-(4-hydroxyphenyl)-3-{me...)
Affinity DataIC50:  37nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50271772((3S,6S)-7-(3-Cyclohexyl-propyl)-6-(4-methoxy-benzy...)
Affinity DataIC50:  37nMAssay Description:Inhibitory activity for kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188178(4-[(2S)-3-{[(2S)-1-(benzylamino)-3-(4-hydroxypheny...)
Affinity DataIC50:  38nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188198(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S,3R)-1-[...)
Affinity DataIC50:  41nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188193(4-[(2S)-2-amino-3-{ethyl[(2S)-1-{ethyl[(2S)-1-[(2S...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity against mu opioid receptor in guinea-pig ileum assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188192(4-[(2S)-3-{[(2S)-1-{[(2S)-1-amino-3-phenylpropan-2...)
Affinity DataIC50:  47nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188206(4-[(2S,5S,8S,11S,14S)-2-{[(2S)-2-(aminomethyl)pyrr...)
Affinity DataIC50:  48nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50369456(5,6,7,8-TETRAHYDROISOQUINOLINE)
Affinity DataIC50:  56nMAssay Description:Inhibitory activity towards Sigma opioid receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188196(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S,3R)-1-{...)
Affinity DataIC50:  61nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM7837(CHEMBL122334 | Hydantoin Derivative 36 | imidazoli...)
Affinity DataIC50:  62nMAssay Description:Inhibitory activity towards Sigma opioid receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188201((2S,5S,8S,11S,14S,17S)-2-(aminomethyl)-8,11-dibenz...)
Affinity DataIC50:  66nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188162(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S)-1-{[(2...)
Affinity DataIC50:  67nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188162(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S)-1-{[(2...)
Affinity DataIC50:  67nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188158((4S,7S,10S,13S,16S,17R)-16-({[(2S)-1-amino-3-(4-hy...)
Affinity DataIC50:  78nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188160(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S)-1-[(2S...)
Affinity DataIC50:  79nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188148((4S,7S,10S,13S,16S,17R)-16-{[(2S)-2-(aminomethyl)p...)
Affinity DataIC50:  82nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50188207(4-[(2S)-3-{[(2S)-1-{[(2S)-1-[(2S)-2-({[(2S)-1-{[(2...)
Affinity DataIC50:  83nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 184 total ) | Next | Last >>
Jump to: