Compile Data Set for Download or QSAR
Found 69 of affinity data for UniProtKB/TrEMBL: Q6NXT6
LigandPNGBDBM575109(US11459321, Example 48)
Show SMILES Cc1cn(c(C)n1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)N2CCS(=O)(=O)CC2)s1
Show InChI InChI=1S/C28H31N5O2S2/c1-20-18-33(21(2)30-20)26-8-5-23-9-10-32(19-24(23)16-26)28-29-17-27(36-28)15-22-3-6-25(7-4-22)31-11-13-37(34,35)14-12-31/h3-8,16-18H,9-15,19H2,1-2H3
Affinity DataIC50: 195nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575064(US11459321, Example 16)
Show SMILES C(c1cnc(s1)N1CCc2ccc(cc2C1)-c1nc[nH]n1)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C24H21N7S/c1-9-28-31(10-1)21-6-2-17(3-7-21)12-22-14-25-24(32-22)30-11-8-18-4-5-19(13-20(18)15-30)23-26-16-27-29-23/h1-7,9-10,13-14,16H,8,11-12,15H2,(H,26,27,29)
Affinity DataIC50: 200nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575077(US11459321, Example 22)
Show SMILES COc1ccc(Cc2cnc(s2)N2CCc3ccc(cc3C2)-n2cc(C)nc2C)cc1-n1cccn1
Show InChI InChI=1S/C28H28N6OS/c1-19-17-33(20(2)31-19)24-7-6-22-9-12-32(18-23(22)15-24)28-29-16-25(36-28)13-21-5-8-27(35-3)26(14-21)34-11-4-10-30-34/h4-8,10-11,14-17H,9,12-13,18H2,1-3H3
Affinity DataIC50: 306nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575106(US11459321, Example 56)
Show SMILES Cc1cn(c(C)n1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)N2CCOC2=O)s1
Show InChI InChI=1S/C27H27N5O2S/c1-18-16-32(19(2)29-18)24-8-5-21-9-10-30(17-22(21)14-24)26-28-15-25(35-26)13-20-3-6-23(7-4-20)31-11-12-34-27(31)33/h3-8,14-16H,9-13,17H2,1-2H3
Affinity DataIC50: 317nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575082(US11459321, Example 27)
Show SMILES COc1cc(Cc2cnc(s2)N2CCc3ccc(cc3C2)-n2cc(C)nc2C)ccc1-n1cccn1
Show InChI InChI=1S/C28H28N6OS/c1-19-17-33(20(2)31-19)24-7-6-22-9-12-32(18-23(22)15-24)28-29-16-25(36-28)13-21-5-8-26(27(14-21)35-3)34-11-4-10-30-34/h4-8,10-11,14-17H,9,12-13,18H2,1-3H3
Affinity DataIC50: 345nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575079(US11459321, Example 24)
Show SMILES O=C1OCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Show InChI InChI=1S/C25H23N5O2S/c31-25-29(12-13-32-25)22-7-4-19-8-11-28(17-20(19)15-22)24-26-16-23(33-24)14-18-2-5-21(6-3-18)30-10-1-9-27-30/h1-7,9-10,15-16H,8,11-14,17H2
Affinity DataIC50: 353nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575119(US11459321, Example 62)
Show SMILES O=C1OCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)C2CCOCC2)s1
Show InChI InChI=1S/C27H29N3O3S/c31-27-30(11-14-33-27)24-6-5-21-7-10-29(18-23(21)16-24)26-28-17-25(34-26)15-19-1-3-20(4-2-19)22-8-12-32-13-9-22/h1-6,16-17,22H,7-15,18H2
Affinity DataIC50: 362nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575091(US11459321, Example 73)
Show SMILES O=C1CCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Show InChI InChI=1S/C26H25N5OS/c32-25-3-1-12-30(25)23-9-6-20-10-14-29(18-21(20)16-23)26-27-17-24(33-26)15-19-4-7-22(8-5-19)31-13-2-11-28-31/h2,4-9,11,13,16-17H,1,3,10,12,14-15,18H2
Affinity DataIC50: 423nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575069(US11459321, Example 14)
Show SMILES Cc1cn(c(C)n1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Show InChI InChI=1S/C27H26N6S/c1-19-17-32(20(2)30-19)25-9-6-22-10-13-31(18-23(22)15-25)27-28-16-26(34-27)14-21-4-7-24(8-5-21)33-12-3-11-29-33/h3-9,11-12,15-17H,10,13-14,18H2,1-2H3
Affinity DataIC50: 453nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575063(US11459321, Example 9)
Show SMILES C(c1cnc(s1)N1CCc2ccc(cc2C1)-n1ccnc1)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C25H22N6S/c1-9-28-31(11-1)22-5-2-19(3-6-22)14-24-16-27-25(32-24)29-12-8-20-4-7-23(15-21(20)17-29)30-13-10-26-18-30/h1-7,9-11,13,15-16,18H,8,12,14,17H2
Affinity DataIC50: 479nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575110(US11459321, Example 49)
Show SMILES O=C1CCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-c2ncccn2)s1
Show InChI InChI=1S/C27H25N5OS/c33-25-3-1-13-32(25)23-9-8-20-10-14-31(18-22(20)16-23)27-30-17-24(34-27)15-19-4-6-21(7-5-19)26-28-11-2-12-29-26/h2,4-9,11-12,16-17H,1,3,10,13-15,18H2
Affinity DataIC50: 516nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575100(US11459321, Example 72)
Show SMILES C(c1cnc(s1)N1CCc2ccc(cc2C1)N1CCOCC1)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C26H27N5OS/c1-9-28-31(10-1)23-5-2-20(3-6-23)16-25-18-27-26(33-25)30-11-8-21-4-7-24(17-22(21)19-30)29-12-14-32-15-13-29/h1-7,9-10,17-18H,8,11-16,19H2
Affinity DataIC50: 537nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575104(US11459321, Example 44)
Show SMILES Cc1cn(c(C)n1)-c1ccc(Cc2cnc(s2)N2CCc3ccc(cc3C2)N2CCOC2=O)cc1
Show InChI InChI=1S/C27H27N5O2S/c1-18-16-32(19(2)29-18)23-6-3-20(4-7-23)13-25-15-28-26(35-25)30-10-9-21-5-8-24(14-22(21)17-30)31-11-12-34-27(31)33/h3-8,14-16H,9-13,17H2,1-2H3
Affinity DataIC50: 552nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575095(US11459321, Example 41)
Show SMILES O=C1OCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(nc2)-n2cccn2)s1
Show InChI InChI=1S/C24H22N6O2S/c31-24-29(10-11-32-24)20-4-3-18-6-9-28(16-19(18)13-20)23-26-15-21(33-23)12-17-2-5-22(25-14-17)30-8-1-7-27-30/h1-5,7-8,13-15H,6,9-12,16H2
Affinity DataIC50: 553nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575107(US11459321, Example 46)
Show SMILES Cc1cn(c(C)n1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)N2CCOCC2)s1
Show InChI InChI=1S/C28H31N5OS/c1-20-18-33(21(2)30-20)26-8-5-23-9-10-32(19-24(23)16-26)28-29-17-27(35-28)15-22-3-6-25(7-4-22)31-11-13-34-14-12-31/h3-8,16-18H,9-15,19H2,1-2H3
Affinity DataIC50: 605nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575111(US11459321, Example 50)
Show SMILES O=C1CCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)N2CCOCC2)s1
Show InChI InChI=1S/C27H30N4O2S/c32-26-2-1-10-31(26)24-8-5-21-9-11-30(19-22(21)17-24)27-28-18-25(34-27)16-20-3-6-23(7-4-20)29-12-14-33-15-13-29/h3-8,17-18H,1-2,9-16,19H2
Affinity DataIC50: 613nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575102(US11459321, Example 43)
Show SMILES CS(=O)(=O)c1ccc(Cc2cnc(s2)N2CCc3ccc(cc3C2)N2CCOC2=O)cc1
Show InChI InChI=1S/C23H23N3O4S2/c1-32(28,29)21-6-2-16(3-7-21)12-20-14-24-22(31-20)25-9-8-17-4-5-19(13-18(17)15-25)26-10-11-30-23(26)27/h2-7,13-14H,8-12,15H2,1H3
Affinity DataIC50: 617nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575088(US11459321, Example 34)
Show SMILES CS(=O)(=O)c1cccc(Cc2cnc(s2)N2CCc3ccc(cc3C2)N2CCOC2=O)c1
Show InChI InChI=1S/C23H23N3O4S2/c1-32(28,29)21-4-2-3-16(12-21)11-20-14-24-22(31-20)25-8-7-17-5-6-19(13-18(17)15-25)26-9-10-30-23(26)27/h2-6,12-14H,7-11,15H2,1H3
Affinity DataIC50: 633nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575081(US11459321, Example 26)
Show SMILES CN1CCN(C1=O)c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Show InChI InChI=1S/C26H26N6OS/c1-29-13-14-31(26(29)33)23-8-5-20-9-12-30(18-21(20)16-23)25-27-17-24(34-25)15-19-3-6-22(7-4-19)32-11-2-10-28-32/h2-8,10-11,16-17H,9,12-15,18H2,1H3
Affinity DataIC50: 637nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575090(US11459321, Example 36)
Show SMILES O=C1OCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)N2CCS(=O)(=O)CC2)s1
Show InChI InChI=1S/C26H28N4O4S2/c31-26-30(9-12-34-26)23-6-3-20-7-8-29(18-21(20)16-23)25-27-17-24(35-25)15-19-1-4-22(5-2-19)28-10-13-36(32,33)14-11-28/h1-6,16-17H,7-15,18H2
Affinity DataIC50: 666nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575078(US11459321, Example 23)
Show SMILES Cc1cn(c(C)n1)-c1ccc(Cc2cnc(s2)N2CCc3ccc(cc3C2)-n2cc(C)nc2C)cc1
Show InChI InChI=1S/C29H30N6S/c1-19-16-34(21(3)31-19)26-8-5-23(6-9-26)13-28-15-30-29(36-28)33-12-11-24-7-10-27(14-25(24)18-33)35-17-20(2)32-22(35)4/h5-10,14-17H,11-13,18H2,1-4H3
Affinity DataIC50: 707nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575122(US11459321, Example 59)
Show SMILES CN1CCCN(C1=O)c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)C2CCOCC2)s1
Show InChI InChI=1S/C29H34N4O2S/c1-31-12-2-13-33(29(31)34)26-8-7-23-9-14-32(20-25(23)18-26)28-30-19-27(36-28)17-21-3-5-22(6-4-21)24-10-15-35-16-11-24/h3-8,18-19,24H,2,9-17,20H2,1H3
Affinity DataIC50: 730nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575112(US11459321, Example 51)
Show SMILES O=C1CCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)N2CCS(=O)(=O)CC2)s1
Show InChI InChI=1S/C27H30N4O3S2/c32-26-2-1-10-31(26)24-8-5-21-9-11-30(19-22(21)17-24)27-28-18-25(35-27)16-20-3-6-23(7-4-20)29-12-14-36(33,34)15-13-29/h3-8,17-18H,1-2,9-16,19H2
Affinity DataIC50: 737nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575114(US11459321, Example 57)
Show SMILES CN1CCN(C1=O)c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)N2CCOC2=O)s1
Show InChI InChI=1S/C26H27N5O3S/c1-28-10-11-30(25(28)32)22-7-4-19-8-9-29(17-20(19)15-22)24-27-16-23(35-24)14-18-2-5-21(6-3-18)31-12-13-34-26(31)33/h2-7,15-16H,8-14,17H2,1H3
Affinity DataIC50: 742nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575070(US11459321, Example 17)
Show SMILES C(c1cnc(s1)N1CCc2ccc(cc2C1)-n1ccnc1)c1ccc(cc1)-n1ccnc1
Show InChI InChI=1S/C25H22N6S/c1-4-22(30-11-8-26-17-30)5-2-19(1)13-24-15-28-25(32-24)29-10-7-20-3-6-23(14-21(20)16-29)31-12-9-27-18-31/h1-6,8-9,11-12,14-15,17-18H,7,10,13,16H2
Affinity DataIC50: 748nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM574849(US11459321, Example 4)
Show SMILES C(c1cnc(s1)N1CCc2ccc(cc2C1)-c1c[nH]nn1)c1cccc(c1)-n1cccn1
Show InChI InChI=1S/C24H21N7S/c1-3-17(11-21(4-1)31-9-2-8-27-31)12-22-14-25-24(32-22)30-10-7-18-5-6-19(13-20(18)16-30)23-15-26-29-28-23/h1-6,8-9,11,13-15H,7,10,12,16H2,(H,26,28,29)
Affinity DataIC50: 758nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575108(US11459321, Example 47)
Show SMILES Cc1cnc(C)n1-c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)N2CCOCC2)s1
Show InChI InChI=1S/C28H31N5OS/c1-20-17-29-21(2)33(20)26-8-5-23-9-10-32(19-24(23)16-26)28-30-18-27(35-28)15-22-3-6-25(7-4-22)31-11-13-34-14-12-31/h3-8,16-18H,9-15,19H2,1-2H3
Affinity DataIC50: 796nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575085(US11459321, Example 31)
Show SMILES O=C1OCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)N2CCOCC2)s1
Show InChI InChI=1S/C26H28N4O3S/c31-26-30(11-14-33-26)23-6-3-20-7-8-29(18-21(20)16-23)25-27-17-24(34-25)15-19-1-4-22(5-2-19)28-9-12-32-13-10-28/h1-6,16-17H,7-15,18H2
Affinity DataIC50: 803nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM574980(US11459321, Example 5)
Show SMILES C(c1cnc(s1)N1CCc2ccc(cc2C1)-c1c[nH]nn1)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C24H21N7S/c1-9-27-31(10-1)21-6-2-17(3-7-21)12-22-14-25-24(32-22)30-11-8-18-4-5-19(13-20(18)16-30)23-15-26-29-28-23/h1-7,9-10,13-15H,8,11-12,16H2,(H,26,28,29)
Affinity DataIC50: 807nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575094(US11459321, Example 29)
Show SMILES O=C1OCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-c2ncccn2)s1
Show InChI InChI=1S/C26H23N5O2S/c32-26-31(12-13-33-26)22-7-6-19-8-11-30(17-21(19)15-22)25-29-16-23(34-25)14-18-2-4-20(5-3-18)24-27-9-1-10-28-24/h1-7,9-10,15-16H,8,11-14,17H2
Affinity DataIC50: 858nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575089(US11459321, Example 35)
Show SMILES O=C1OCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2cccc(c2)N2CCOCC2)s1
Show InChI InChI=1S/C26H28N4O3S/c31-26-30(10-13-33-26)23-5-4-20-6-7-29(18-21(20)16-23)25-27-17-24(34-25)15-19-2-1-3-22(14-19)28-8-11-32-12-9-28/h1-5,14,16-17H,6-13,15,18H2
Affinity DataIC50: 891nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575087(US11459321, Example 33)
Show SMILES O=C1OCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2cccc(c2)N2CCS(=O)(=O)CC2)s1
Show InChI InChI=1S/C26H28N4O4S2/c31-26-30(8-11-34-26)23-5-4-20-6-7-29(18-21(20)16-23)25-27-17-24(35-25)15-19-2-1-3-22(14-19)28-9-12-36(32,33)13-10-28/h1-5,14,16-17H,6-13,15,18H2
Affinity DataIC50: 903nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575080(US11459321, Example 25)
Show SMILES O=C1NCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Show InChI InChI=1S/C25H24N6OS/c32-24-26-10-13-30(24)22-7-4-19-8-12-29(17-20(19)15-22)25-27-16-23(33-25)14-18-2-5-21(6-3-18)31-11-1-9-28-31/h1-7,9,11,15-16H,8,10,12-14,17H2,(H,26,32)
Affinity DataIC50: 911nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575093(US11459321, Example 40)
Show SMILES O=C1OCCN1c1cccc(Cc2cnc(s2)N2CCc3ccc(cc3C2)N2CCOC2=O)c1
Show InChI InChI=1S/C25H24N4O4S/c30-24-28(8-10-32-24)20-3-1-2-17(12-20)13-22-15-26-23(34-22)27-7-6-18-4-5-21(14-19(18)16-27)29-9-11-33-25(29)31/h1-5,12,14-15H,6-11,13,16H2
Affinity DataIC50: 956nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575086(US11459321, Example 32)
Show SMILES O=C1OCCN1c1ccc(Cc2cnc(s2)N2CCc3ccc(cc3C2)N2CCOC2=O)cc1
Show InChI InChI=1S/C25H24N4O4S/c30-24-28(9-11-32-24)20-4-1-17(2-5-20)13-22-15-26-23(34-22)27-8-7-18-3-6-21(14-19(18)16-27)29-10-12-33-25(29)31/h1-6,14-15H,7-13,16H2
Affinity DataIC50: 979nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575068(US11459321, Example 13)
Show SMILES Cc1cn(cn1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Show InChI InChI=1S/C26H24N6S/c1-19-16-31(18-28-19)24-8-5-21-9-12-30(17-22(21)14-24)26-27-15-25(33-26)13-20-3-6-23(7-4-20)32-11-2-10-29-32/h2-8,10-11,14-16,18H,9,12-13,17H2,1H3
Affinity DataIC50: 1.06E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575071(US11459321, Example 18)
Show SMILES C(c1cnc(s1)N1CCc2cc(ccc2C1)-n1ccnc1)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C25H22N6S/c1-9-28-31(11-1)22-5-2-19(3-6-22)14-24-16-27-25(32-24)29-12-8-20-15-23(7-4-21(20)17-29)30-13-10-26-18-30/h1-7,9-11,13,15-16,18H,8,12,14,17H2
Affinity DataIC50: 1.08E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575117(US11459321, Example 54)
Show SMILES C(c1cnc(s1)N1CCc2ccc(cc2C1)N1CCOCC1)c1ccc(cc1)-c1ncccn1
Show InChI InChI=1S/C27H27N5OS/c1-9-28-26(29-10-1)22-4-2-20(3-5-22)16-25-18-30-27(34-25)32-11-8-21-6-7-24(17-23(21)19-32)31-12-14-33-15-13-31/h1-7,9-10,17-18H,8,11-16,19H2
Affinity DataIC50: 1.10E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575116(US11459321, Example 58)
Show SMILES O=C1OCCN1c1ccc(Cc2cnc(s2)N2CCc3ccc(cc3C2)N2CCOCC2)cc1
Show InChI InChI=1S/C26H28N4O3S/c31-26-30(11-14-33-26)22-4-1-19(2-5-22)15-24-17-27-25(34-24)29-8-7-20-3-6-23(16-21(20)18-29)28-9-12-32-13-10-28/h1-6,16-17H,7-15,18H2
Affinity DataIC50: 1.13E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM574850(US11459321, Example 2)
Show SMILES Cn1cc(nn1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Show InChI InChI=1S/C25H23N7S/c1-30-17-24(28-29-30)20-6-5-19-9-12-31(16-21(19)14-20)25-26-15-23(33-25)13-18-3-7-22(8-4-18)32-11-2-10-27-32/h2-8,10-11,14-15,17H,9,12-13,16H2,1H3
Affinity DataIC50: 1.17E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575074(US11459321, Example 67)
Show SMILES Cc1cn(c(C)n1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2cncc(c2)-n2cccn2)s1
Show InChI InChI=1S/C26H25N7S/c1-18-16-32(19(2)30-18)23-5-4-21-6-9-31(17-22(21)12-23)26-28-15-25(34-26)11-20-10-24(14-27-13-20)33-8-3-7-29-33/h3-5,7-8,10,12-16H,6,9,11,17H2,1-2H3
Affinity DataIC50: 1.19E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575072(US11459321, Example 19)
Show SMILES Cc1cn(c(C)n1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2cccc(c2)-n2cccn2)s1
Show InChI InChI=1S/C27H26N6S/c1-19-17-32(20(2)30-19)24-8-7-22-9-12-31(18-23(22)15-24)27-28-16-26(34-27)14-21-5-3-6-25(13-21)33-11-4-10-29-33/h3-8,10-11,13,15-17H,9,12,14,18H2,1-2H3
Affinity DataIC50: 1.30E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575115(US11459321, Example 52)
Show SMILES CN1CCN(C1=O)c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-c2ncccn2)s1
Show InChI InChI=1S/C27H26N6OS/c1-31-13-14-33(27(31)34)23-8-7-20-9-12-32(18-22(20)16-23)26-30-17-24(35-26)15-19-3-5-21(6-4-19)25-28-10-2-11-29-25/h2-8,10-11,16-17H,9,12-15,18H2,1H3
Affinity DataIC50: 1.36E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575061(US11459321, Example 7)
Show SMILES COCCn1nncc1-c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Show InChI InChI=1S/C27H27N7OS/c1-35-14-13-34-26(18-29-31-34)22-6-5-21-9-12-32(19-23(21)16-22)27-28-17-25(36-27)15-20-3-7-24(8-4-20)33-11-2-10-30-33/h2-8,10-11,16-18H,9,12-15,19H2,1H3
Affinity DataIC50: 1.70E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575065(US11459321, Example 11)
Show SMILES COCCn1cc(nn1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Show InChI InChI=1S/C27H27N7OS/c1-35-14-13-33-19-26(30-31-33)22-6-5-21-9-12-32(18-23(21)16-22)27-28-17-25(36-27)15-20-3-7-24(8-4-20)34-11-2-10-29-34/h2-8,10-11,16-17,19H,9,12-15,18H2,1H3
Affinity DataIC50: 1.70E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575120(US11459321, Example 45)
Show SMILES COCCN1CCCN(C1=O)c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Show InChI InChI=1S/C29H32N6O2S/c1-37-17-16-32-12-3-13-34(29(32)36)26-9-6-23-10-15-33(21-24(23)19-26)28-30-20-27(38-28)18-22-4-7-25(8-5-22)35-14-2-11-31-35/h2,4-9,11,14,19-20H,3,10,12-13,15-18,21H2,1H3
Affinity DataIC50: 1.78E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575067(US11459321, Example 15)
Show SMILES C(c1cnc(s1)N1CCc2ccc(cc2C1)-c1nc[nH]n1)c1cccc(c1)-n1cccn1
Show InChI InChI=1S/C24H21N7S/c1-3-17(11-21(4-1)31-9-2-8-28-31)12-22-14-25-24(32-22)30-10-7-18-5-6-19(13-20(18)15-30)23-26-16-27-29-23/h1-6,8-9,11,13-14,16H,7,10,12,15H2,(H,26,27,29)
Affinity DataIC50: 1.85E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575083(US11459321, Example 28)
Show SMILES O=C1OCCN1c1ccc2CCN(Cc2c1)c1ncc(Cc2cccc(c2)-n2cccn2)s1
Show InChI InChI=1S/C25H23N5O2S/c31-25-29(11-12-32-25)21-6-5-19-7-10-28(17-20(19)15-21)24-26-16-23(33-24)14-18-3-1-4-22(13-18)30-9-2-8-27-30/h1-6,8-9,13,15-16H,7,10-12,14,17H2
Affinity DataIC50: 1.89E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM574951(US11459321, Example 3)
Show SMILES Cn1cc(nn1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2cccc(c2)-n2cccn2)s1
Show InChI InChI=1S/C25H23N7S/c1-30-17-24(28-29-30)20-7-6-19-8-11-31(16-21(19)14-20)25-26-15-23(33-25)13-18-4-2-5-22(12-18)32-10-3-9-27-32/h2-7,9-10,12,14-15,17H,8,11,13,16H2,1H3
Affinity DataIC50: 1.91E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM575062(US11459321, Example 8)
Show SMILES COCCn1nncc1-c1ccc2CCN(Cc2c1)c1ncc(Cc2cccc(c2)-n2cccn2)s1
Show InChI InChI=1S/C27H27N7OS/c1-35-13-12-34-26(18-29-31-34)22-7-6-21-8-11-32(19-23(21)16-22)27-28-17-25(36-27)15-20-4-2-5-24(14-20)33-10-3-9-30-33/h2-7,9-10,14,16-18H,8,11-13,15,19H2,1H3
Affinity DataIC50: 2.01E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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