Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50031724
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317988(N-(4-amino-4'-fluorobiphenyl-3-yl)benzamide | CHEM...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50318000(N-(2-amino-5-(furan-3-yl)phenyl)benzamide | CHEMBL...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317996(N-(2-amino-5-(furan-2-yl)phenyl)benzamide | CHEMBL...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317998(N-(4-amino-4'-methoxybiphenyl-3-yl)benzamide | CHE...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317999(N-(2-amino-5-(pyridin-4-yl)phenyl)benzamide | CHEM...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50318003(N-(2-amino-5-(thiazol-2-yl)phenyl)benzamide | CHEM...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317990(N-(4-amino-4'-bromobiphenyl-3-yl)benzamide | CHEMB...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50318002(N-(4-amino-4'-vinylbiphenyl-3-yl)benzamide | CHEMB...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50318000(N-(2-amino-5-(furan-3-yl)phenyl)benzamide | CHEMBL...)
Affinity DataIC50: 810nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317998(N-(4-amino-4'-methoxybiphenyl-3-yl)benzamide | CHE...)
Affinity DataIC50: 860nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317991(N-(4-amino-3'-methoxybiphenyl-3-yl)benzamide | CHE...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317988(N-(4-amino-4'-fluorobiphenyl-3-yl)benzamide | CHEM...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317996(N-(2-amino-5-(furan-2-yl)phenyl)benzamide | CHEMBL...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317995(N-(4-amino-3'-methylbiphenyl-3-yl)benzamide | CHEM...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50232046(N-(2-aminophenyl)benzamide | CHEMBL405072)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317991(N-(4-amino-3'-methoxybiphenyl-3-yl)benzamide | CHE...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317997(N-(4'-acetyl-4-aminobiphenyl-3-yl)benzamide | CHEM...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317987(N-(4-amino-4'-(trifluoromethyl)biphenyl-3-yl)benza...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317999(N-(2-amino-5-(pyridin-4-yl)phenyl)benzamide | CHEM...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317997(N-(4'-acetyl-4-aminobiphenyl-3-yl)benzamide | CHEM...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50318002(N-(4-amino-4'-vinylbiphenyl-3-yl)benzamide | CHEMB...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50318003(N-(2-amino-5-(thiazol-2-yl)phenyl)benzamide | CHEM...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317995(N-(4-amino-3'-methylbiphenyl-3-yl)benzamide | CHEM...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317993(N-(2-amino-5-(benzo[b]thiophen-3-yl)phenyl)benzami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317989(N-(2-amino-5-(benzofuran-2-yl)phenyl)benzamide | C...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50232046(N-(2-aminophenyl)benzamide | CHEMBL405072)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317993(N-(2-amino-5-(benzo[b]thiophen-3-yl)phenyl)benzami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50318001(N-(2-amino-5-(benzo[b]thiophen-2-yl)phenyl)benzami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317989(N-(2-amino-5-(benzofuran-2-yl)phenyl)benzamide | C...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50318001(N-(2-amino-5-(benzo[b]thiophen-2-yl)phenyl)benzami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317992(N-(3'-acetyl-4-aminobiphenyl-3-yl)benzamide | CHEM...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317994(N-(4-amino-3'-nitrobiphenyl-3-yl)benzamide | CHEMB...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317990(N-(4-amino-4'-bromobiphenyl-3-yl)benzamide | CHEMB...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317992(N-(3'-acetyl-4-aminobiphenyl-3-yl)benzamide | CHEM...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317987(N-(4-amino-4'-(trifluoromethyl)biphenyl-3-yl)benza...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317994(N-(4-amino-3'-nitrobiphenyl-3-yl)benzamide | CHEMB...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed