Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50009423
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataIC50:  21nMAssay Description:Induction of desensitization at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine induced current treate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataIC50:  710nMAssay Description:Antagonist activity at human 5-HT3A receptor expressed in Xenopus laevis oocytes at -90 mV holding potential in presence of serotonin by two-electrod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataIC50:  1.01E+4nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes preincubated with 1 uM alpha7 type-2 PAM PNU-120596 at -90 mV holding pote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528724(CHEMBL4473334)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528719(CHEMBL4475776)
Affinity DataEC50:  1.27E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataEC50:  6.14E+3nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin) expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528723(CHEMBL4527227)
Affinity DataEC50:  7.63E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataEC50:  1.88E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528721(CHEMBL4438623)
Affinity DataEC50:  8.27E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528720(CHEMBL4454650)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataEC50:  250nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair