Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50010288
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537168(CHEMBL4541987)
Affinity DataEC50:  6nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537156(CHEMBL4521766)
Affinity DataEC50:  6nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537146(CHEMBL4574815)
Affinity DataEC50:  7nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537157(CHEMBL4593726)
Affinity DataEC50:  7nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537162(CHEMBL4570149)
Affinity DataEC50:  7nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537167(CHEMBL4550501)
Affinity DataEC50:  8nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537155(CHEMBL4577230)
Affinity DataEC50:  8nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataEC50:  9nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537145(CHEMBL4526297)
Affinity DataEC50:  12nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537161(CHEMBL4514739)
Affinity DataEC50:  14nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537153(CHEMBL4538711)
Affinity DataEC50:  17nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50153594(CHEMBL3774855)
Affinity DataEC50:  34nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537150(CHEMBL4514309)
Affinity DataEC50:  44nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537154(CHEMBL4581769)
Affinity DataEC50:  56nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537159(CHEMBL4542908)
Affinity DataEC50:  62nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537166(CHEMBL4560329)
Affinity DataEC50:  120nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537163(CHEMBL4554291)
Affinity DataEC50:  190nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537144(CHEMBL4513426)
Affinity DataEC50:  440nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537151(CHEMBL4569071)
Affinity DataEC50:  660nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50153652(CHEMBL3774985)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537165(CHEMBL4536161)
Affinity DataEC50:  2.70E+3nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537152(CHEMBL4569327)
Affinity DataEC50:  3.80E+3nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537149(CHEMBL4532088)
Affinity DataEC50:  6.40E+3nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537164(CHEMBL4515215)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537160(CHEMBL4539449)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537169(CHEMBL4529082)
Affinity DataEC50:  1.90E+4nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537158(CHEMBL4514578)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537148(CHEMBL4544876)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of GAL4-fused human PPARgamma transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-alpha(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of GAL4-fused human RORalpha transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of GAL4-fused human RXR transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of GAL4-fused human PPARdelta transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataIC50: 5.00E+4nMAssay Description:Time-dependent inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataIC50: 5.00E+4nMAssay Description:Time-dependent inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataIC50: 5.00E+4nMAssay Description:Time-dependent inhibition of human CYP3A4 using testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataIC50: 5.00E+4nMAssay Description:Time-dependent inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataIC50: 5.00E+4nMAssay Description:Time-dependent inhibition of human CYP3A4 using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataIC50: 5.00E+4nMAssay Description:Time-dependent inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed