Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50013771
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50426967(CHEMBL2325079 | PF-4693627)
Affinity DataIC50:  3nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Mus musculus)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569442(CHEMBL4864480)
Affinity DataIC50:  60nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569443(CHEMBL4851179)
Affinity DataIC50:  150nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGE2 production incubated for 24 hrs by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569444(CHEMBL4848472)
Affinity DataIC50:  160nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGE2 production incubated for 24 hrs by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569442(CHEMBL4864480)
Affinity DataIC50:  190nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGE2 production incubated for 24 hrs by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569446(CHEMBL4870406)
Affinity DataIC50:  240nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGE2 production incubated for 24 hrs by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569442(CHEMBL4864480)
Affinity DataIC50:  250nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGI2 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Mus musculus)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569444(CHEMBL4848472)
Affinity DataIC50:  340nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569446(CHEMBL4870406)
Affinity DataIC50:  490nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50426967(CHEMBL2325079 | PF-4693627)
Affinity DataIC50:  520nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGE2 production incubated for 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569442(CHEMBL4864480)
Affinity DataIC50:  610nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569445(CHEMBL4848316)
Affinity DataIC50:  610nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGE2 production incubated for 24 hrs by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569446(CHEMBL4870406)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGI2 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569444(CHEMBL4848472)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGI2 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells by cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569444(CHEMBL4848472)
Affinity DataIC50:  5.20E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569444(CHEMBL4848472)
Affinity DataIC50:  7.37E+3nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells by cell-free assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569442(CHEMBL4864480)
Affinity DataIC50:  9.60E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569446(CHEMBL4870406)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569445(CHEMBL4848316)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569443(CHEMBL4851179)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed