Compile Data Set for Download or QSAR
Report error Found 119 Enz. Inhib. hit(s) with all data for entry = 9776
TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488058BDBM488058(N-(4-(4-(2- Methoxyethyl)piperazin- 1-yl)phenyl)-4...)
Affinity DataIC50: 1.30nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488080BDBM488080(N-(4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)...)
Affinity DataIC50: 2.70nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488104BDBM488104(N-(4-(4-Amino-4- ethylpiperidin-1- yl)phenyl)-4-(1...)
Affinity DataIC50: 3nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488104BDBM488104(N-(4-(4-Amino-4- ethylpiperidin-1- yl)phenyl)-4-(1...)
Affinity DataIC50: 3.5nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488093BDBM488093(3-((4-(2-((4- (Piperazin-1- yl)phenyl)amino) pyrim...)
Affinity DataIC50: 5.40nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488032BDBM488032(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50: 5.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488094BDBM488094(2-((4-(2-((4- (Piperazin-1- yl)phenyl)amino) pyrim...)
Affinity DataIC50: 5.60nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488089BDBM488089(4-(1-(2,2- Difluoroethyl)-3- (pyridin-3-yl)-1H- py...)
Affinity DataIC50: 5.60nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488039BDBM488039(N-(4-(4- (Cyclopropylmethyl) piperazin-1-yl)phenyl...)
Affinity DataIC50: 5.70nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488093BDBM488093(3-((4-(2-((4- (Piperazin-1- yl)phenyl)amino) pyrim...)
Affinity DataIC50: 6.10nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488038BDBM488038(N-(4-(4- Cyclopropylpiperazin- 1-yl)phenyl)-4-(1- ...)
Affinity DataIC50: 6.10nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488039BDBM488039(N-(4-(4- (Cyclopropylmethyl) piperazin-1-yl)phenyl...)
Affinity DataIC50: 6.10nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488079BDBM488079((4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- y...)
Affinity DataIC50: 6.30nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488032BDBM488032(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50: 6.60nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488054BDBM488054(2-Methyl-1-(4-(2-((2- methyl-1,2,3,4- tetrahydrois...)
Affinity DataIC50: 6.70nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488066BDBM488066(N-(4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)...)
Affinity DataIC50: 7.10nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488059BDBM488059(N-(4-(4-(2- Methoxyethyl)piperazin- 1-yl)phenyl)-4...)
Affinity DataIC50: 7.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488041BDBM488041(4-(1-(2- Methoxyethyl)-3- (pyridin-3-yl)-1H- pyraz...)
Affinity DataIC50: 7.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488079BDBM488079((4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- y...)
Affinity DataIC50: 7.90nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488050BDBM488050(N-(4-(4-(2-(2,2- Difluoroethoxy)ethyl) piperazin-1...)
Affinity DataIC50: 8nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488062BDBM488062(2-((4-(2-((4-(4-(2- Methoxyethyl)piperazin-1- yl)p...)
Affinity DataIC50: 9.20nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488090BDBM488090(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50: 9.40nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488099BDBM488099(N-(4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)...)
Affinity DataIC50: 9.40nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488075BDBM488075(1-(4-(4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol...)
Affinity DataIC50: 9.90nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488041BDBM488041(4-(1-(2- Methoxyethyl)-3- (pyridin-3-yl)-1H- pyraz...)
Affinity DataIC50: 10.4nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488065BDBM488065(N-(4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)...)
Affinity DataIC50: 10.7nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488098BDBM488098(N-(4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)...)
Affinity DataIC50: 10.9nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488074BDBM488074(1-(4-(4-((4-(1-ethyl-3- (pyridin-3-yl)-1H- pyrazol...)
Affinity DataIC50: 11nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488100BDBM488100(N-(4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)...)
Affinity DataIC50: 11nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488051BDBM488051(1-(4-(4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol...)
Affinity DataIC50: 11.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488048BDBM488048(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50: 11.6nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488053BDBM488053(N-(4-(1-(2- Methoxyethyl)-3- (pyridin-3-yl)-1H- py...)
Affinity DataIC50: 12.6nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488074BDBM488074(1-(4-(4-((4-(1-ethyl-3- (pyridin-3-yl)-1H- pyrazol...)
Affinity DataIC50: 13.2nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488037BDBM488037(2-(4-(4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol...)
Affinity DataIC50: 13.2nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488029BDBM488029((4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- y...)
Affinity DataIC50: 13.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488042BDBM488042(N-(4-(1H-1,2,4- Triazol-1-yl)phenyl)- 4-(1-ethyl-3...)
Affinity DataIC50: 13.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488045BDBM488045(N-(4-(1H-Imidazol-1- yl)phenyl)-4-(1-ethyl- 3-(pyr...)
Affinity DataIC50: 13.6nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488033BDBM488033(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50: 13.9nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488069BDBM488069(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50: 14.3nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488073BDBM488073(N-(4-(4-(2- Methoxyethyl)piperazin- 1-yl)phenyl)-4...)
Affinity DataIC50: 14.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488046BDBM488046(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50: 14.7nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488109BDBM488109(N-(4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4-yl)p...)
Affinity DataIC50: 15nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488114BDBM488114(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50: 15nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488036BDBM488036(N-(4-(1-Ethyl-1H- pyrazol-4-yl)phenyl)- 4-(1-ethyl...)
Affinity DataIC50: 15.1nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488092BDBM488092(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50: 16nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488078BDBM488078(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50: 16.3nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488101BDBM488101(2-(6-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4-...)
Affinity DataIC50: 16.3nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488056BDBM488056(4-(1-(2- Methoxyethyl)-3- (pyridin-3-yl)-1H- pyraz...)
Affinity DataIC50: 17nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488088BDBM488088(4-(1-Ethyl-3-(5- fluoropyridin-3-yl)-1H- pyrazol-4...)
Affinity DataIC50: 17nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandChemical structure of BindingDB Monomer ID 488100BDBM488100(N-(4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)...)
Affinity DataIC50: 17nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

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