Compile Data Set for Download or QSAR
Report error Found 214 Enz. Inhib. hit(s) with all data for entry = 11303
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605617BDBM605617(US11673893, Example 86)
Affinity DataIC50: 0.406nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605531BDBM605531(US11673893, Example 9 | (1S,3R)-N-(5-chloro-4-(7-f...)
Affinity DataIC50: 0.416nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605532BDBM605532(US11673893, Example 10 | (1S,3R)-N-(5-chloro-4-(7-...)
Affinity DataIC50: 0.455nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605523BDBM605523(US11673893, Example 2 | (1S,3R)-N-[5-chloro-4-(7-f...)
Affinity DataIC50: 0.477nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605596BDBM605596(US11673893, Example 65)
Affinity DataIC50: 0.480nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605534BDBM605534(US11673893, Example 12 | (1S,3R)-N-(5-chloro-4-(7-...)
Affinity DataIC50: 0.489nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605533BDBM605533(US11673893, Example 11 | (1S,3R)-N-(5-chloro-4-(7-...)
Affinity DataIC50: 0.498nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605526BDBM605526(US11673893, Example 4 | (1S,3R)-N-(5-chloro-4-(7-f...)
Affinity DataIC50: 0.528nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605551BDBM605551(US11673893, Example 24 | (1S,3R)-3-acetamido-N-(4-...)
Affinity DataIC50: 0.539nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605549BDBM605549(US11673893, Example 22 | (1S,3R)-3-acetamido-N-(4-...)
Affinity DataIC50: 0.694nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605525BDBM605525(US11673893, Example 3 | (1S,3R)-N-(5-chloro-4-(7-f...)
Affinity DataIC50: 0.699nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605573BDBM605573(US11673893, Example 45)
Affinity DataIC50: 0.743nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605529BDBM605529(US11673893, Example 7 | N-[(1R,3S)-3-[[5-chloro-4-...)
Affinity DataIC50: 0.760nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605606BDBM605606(US11673893, Example 76-1)
Affinity DataIC50: 0.780nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605528BDBM605528(US11673893, Example 6 | (1S,3R)-N-[5-chloro-4-(7-f...)
Affinity DataIC50: 0.794nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605581BDBM605581(US11673893, Example 53)
Affinity DataIC50: 0.820nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605618BDBM605618(US11673893, Example 87)
Affinity DataIC50: 0.837nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605604BDBM605604(US11673893, Example 74)
Affinity DataIC50: 0.938nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605592BDBM605592(US11673893, Example 62)
Affinity DataIC50: 0.961nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605571BDBM605571(US11673893, Example 43)
Affinity DataIC50: 0.979nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605530BDBM605530(US11673893, Example 8 | N-((1R,3S)-3-((5-chloro-4-...)
Affinity DataIC50: 0.980nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605572BDBM605572(US11673893, Example 44)
Affinity DataIC50: 0.984nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605558BDBM605558(US11673893, Example 30)
Affinity DataIC50: 1.01nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605563BDBM605563(US11673893, Example 35)
Affinity DataIC50: 1.04nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605527BDBM605527(US11673893, Example 5 | (1S,3R)-N-(5-chloro-4-(7-f...)
Affinity DataIC50: 1.04nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605611BDBM605611(US11673893, Example 80)
Affinity DataIC50: 1.09nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605559BDBM605559(US11673893, Example 31)
Affinity DataIC50: 1.29nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605564BDBM605564(US11673893, Example 36)
Affinity DataIC50: 1.37nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605605BDBM605605(US11673893, Example 75)
Affinity DataIC50: 1.38nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605574BDBM605574(US11673893, Example 46)
Affinity DataIC50: 1.39nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605591BDBM605591(US11673893, Example 61)
Affinity DataIC50: 1.41nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605615BDBM605615(US11673893, Example 84)
Affinity DataIC50: 1.42nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605557BDBM605557(US11673893, Example 29)
Affinity DataIC50: 1.48nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605580BDBM605580(US11673893, Example 52)
Affinity DataIC50: 1.49nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605585BDBM605585(US11673893, Example 56)
Affinity DataIC50: 1.52nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605613BDBM605613(US11673893, Example 82)
Affinity DataIC50: 1.55nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605561BDBM605561(US11673893, Example 33)
Affinity DataIC50: 1.57nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605522BDBM605522(US11673893, Example 1 | (1S,3R)-3-acetamido-N-[5-c...)
Affinity DataIC50: 1.61nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605597BDBM605597(US11673893, Example 66)
Affinity DataIC50: 1.65nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605597BDBM605597(US11673893, Example 66)
Affinity DataIC50: 1.67nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605562BDBM605562(US11673893, Example 34)
Affinity DataIC50: 1.87nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605588BDBM605588(US11673893, Example 59)
Affinity DataIC50: 1.95nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605608BDBM605608(US11673893, Example 77)
Affinity DataIC50: 1.97nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605586BDBM605586(US11673893, Example 57)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605555BDBM605555(US11673893, Example 28)
Affinity DataIC50: 2.23nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605589BDBM605589(US11673893, Example 60)
Affinity DataIC50: 2.27nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605578BDBM605578(US11673893, Example 50)
Affinity DataIC50: 2.30nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605541BDBM605541(US11673893, Example 17 | (1S,3R)-N-(5-chloro-4-(5-...)
Affinity DataIC50: 2.31nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605535BDBM605535(US11673893, Example 13 | (1S,3R)-3-acetamido-N-[5-...)
Affinity DataIC50: 2.31nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 605599BDBM605599(US11673893, Example 69)
Affinity DataIC50: 2.43nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent

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