TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 3.5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 19nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 23nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 29nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 32nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 38nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 51nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 58nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 63nMAssay Description:Inhibitory concentration against human P2X purinoceptor 1 expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 71nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 76nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 77nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 91nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human P2X1R transfected in CHO-K1 cells preincubated for 30 mins followed by alpha,beta-meATP addition by luminescence based a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 172nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 180nMAssay Description:Antagonist activity at P2X1 receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 199nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 210nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 219nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 236nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 236nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 323nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 335nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 341nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 439nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 496nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 522nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 567nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 570nMAssay Description:Antagonist activity P2X1 receptor in Apyrase pre-treated human platelets assessed as inhibition of collagen-induced platelet aggregation pre-incubate...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 602nMAssay Description:Antagonist activity at human P2X1 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 655nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 755nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 869nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 907nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 915nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 1.14E+3nMAssay Description:Antagonist activity P2X1 receptor in Apyrase pre-treated human platelets assessed as inhibition of collagen-induced platelet aggregation pre-incubate...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 1.15E+3nMAssay Description:Affinity at P2X purinoceptor 1 (P2X1) and the value is expressed as IC50More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of P2X1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 1.34E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 1.51E+3nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 1.53E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at P2X1 receptor in HEK293 cells assessed as alpha, beta-methylene ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 1.66E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 1.79E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair