Compile Data Set for Download or QSAR
maximum 50k data
Found 159 of affinity data for UniProtKB/TrEMBL: P51575
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50171290(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM85682(CAS_5311315 | NF279 | NSC_5311315)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50000029(4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM21280(5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)met...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM526264(US11185100, TABLE 14.4)
Affinity DataIC50:  3.5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430160(CHEMBL536151 | TCMDC-125465)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430195(CHEMBL2338696)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430185(CHEMBL2179173)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540434(CHEMBL4640175)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430177(CHEMBL2088014)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540436(CHEMBL2179174)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430156(CHEMBL2338695)
Affinity DataIC50:  58nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50422739(CHEMBL413145)
Affinity DataIC50:  63nMAssay Description:Inhibitory concentration against human P2X purinoceptor 1 expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540422(CHEMBL4644398)
Affinity DataIC50:  71nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540442(CHEMBL2088011)
Affinity DataIC50:  76nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430159(CHEMBL461542)
Affinity DataIC50:  77nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430176(CHEMBL589733 | MMV665807 | SJ000010289)
Affinity DataIC50:  91nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540410(CHEMBL337395)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human P2X1R transfected in CHO-K1 cells preincubated for 30 mins followed by alpha,beta-meATP addition by luminescence based a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540439(CHEMBL2088009)
Affinity DataIC50:  172nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50015276(CHEMBL3263056 | US9428504, 166 | US9428504, 167)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at P2X1 receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540432(CHEMBL2088012)
Affinity DataIC50:  199nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50118228(5,7-Disulfo-4-(3-{3-[3-(4,6,8-trisulfo-naphthalen-...)
Affinity DataIC50:  210nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540449(CHEMBL4637528)
Affinity DataIC50:  219nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50240455(CHEMBL1253351)
Affinity DataIC50:  236nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430194(CHEMBL2313115)
Affinity DataIC50:  236nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430186(CHEMBL2178702)
Affinity DataIC50:  323nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540443(CHEMBL4648128)
Affinity DataIC50:  335nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430170(CHEMBL2338686)
Affinity DataIC50:  341nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540456(CHEMBL2313133)
Affinity DataIC50:  439nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50168286(1H-Benzoimidazole-2-carboxylic acid [(R)-1-((1S,2R...)
Affinity DataIC50:  496nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540441(CHEMBL2179168)
Affinity DataIC50:  522nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540444(CHEMBL2179170)
Affinity DataIC50:  567nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430160(CHEMBL536151 | TCMDC-125465)
Affinity DataIC50:  570nMAssay Description:Antagonist activity P2X1 receptor in Apyrase pre-treated human platelets assessed as inhibition of collagen-induced platelet aggregation pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50399190(CHEMBL2180149)
Affinity DataIC50:  602nMAssay Description:Antagonist activity at human P2X1 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540423(CHEMBL4639803)
Affinity DataIC50:  655nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430193(CHEMBL2313119)
Affinity DataIC50:  755nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540424(CHEMBL3628655)
Affinity DataIC50:  869nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540433(CHEMBL2312822)
Affinity DataIC50:  907nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540435(CHEMBL4634436)
Affinity DataIC50:  915nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540413(CHEMBL2313124)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430195(CHEMBL2338696)
Affinity DataIC50:  1.14E+3nMAssay Description:Antagonist activity P2X1 receptor in Apyrase pre-treated human platelets assessed as inhibition of collagen-induced platelet aggregation pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50118229(CHEMBL129841 | MRS 2179)
Affinity DataIC50:  1.15E+3nMAssay Description:Affinity at P2X purinoceptor 1 (P2X1) and the value is expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50118229(CHEMBL129841 | MRS 2179)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of P2X1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540430(Salfluverine)
Affinity DataIC50:  1.30E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540445(CHEMBL2179166)
Affinity DataIC50:  1.34E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50594498(CHEMBL4583478)
Affinity DataIC50:  1.51E+3nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430161(CHEMBL2313134)
Affinity DataIC50:  1.53E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50445214(CHEMBL3104636)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonist activity at P2X1 receptor in HEK293 cells assessed as alpha, beta-methylene ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430157(CHEMBL2313116)
Affinity DataIC50:  1.66E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540453(CHEMBL4644509)
Affinity DataIC50:  1.79E+3nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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