Compile Data Set for Download or QSAR
Report error Found 86 of affinity data for UniProtKB/TrEMBL: P10145
TargetInterleukin-8(Human)
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LigandChemical structure of BindingDB Monomer ID 277687BDBM277687(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-me...)
Affinity DataIC50: 2.80nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277693BDBM277693(2-((2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3...)
Affinity DataIC50: 2.90nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277686BDBM277686(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)
Affinity DataIC50: 5.60nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277702BDBM277702(5-((2-(3-((4-((4-(3-(5-tert-Butyl)-2-methoxy-3-(me...)
Affinity DataIC50: 7.30nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277688BDBM277688(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)
Affinity DataIC50: 7.30nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277682BDBM277682(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)
Affinity DataIC50: 8nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 13066BDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 8nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
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LigandChemical structure of BindingDB Monomer ID 50295276BDBM50295276(2-(2-(2-fluorophenylamino)phenyl)acetic acid | CHE...)
Affinity DataIC50: 9nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
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PubMed
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LigandChemical structure of BindingDB Monomer ID 50295266BDBM50295266(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanoic a...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
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LigandChemical structure of BindingDB Monomer ID 277694BDBM277694(US10072034, Example 20(a) | US10072034, Example 20...)
Affinity DataIC50: 10.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277683BDBM277683(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 11.7nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277685BDBM277685(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 11.7nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 50295267BDBM50295267(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanamide...)
Affinity DataIC50: 12nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
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PubMed
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LigandChemical structure of BindingDB Monomer ID 50295268BDBM50295268(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(methyls...)
Affinity DataIC50: 13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
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LigandChemical structure of BindingDB Monomer ID 50295281BDBM50295281(2-(2-(2-fluorophenoxy)phenyl)acetic acid | [2-(2-F...)
Affinity DataIC50: 13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 277696BDBM277696(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 14.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277701BDBM277701(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)
Affinity DataIC50: 15.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277690BDBM277690(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(ethylsulf...)
Affinity DataIC50: 16.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277689BDBM277689(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-3-(ethylsulfo...)
Affinity DataIC50: 16.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277691BDBM277691(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl) isoxazol-3-y...)
Affinity DataIC50: 17.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277677BDBM277677(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)
Affinity DataIC50: 17.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277697BDBM277697(1-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 18.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277680BDBM277680(2-(2-(2-(3-((4-((4-(3-(5-tert-Butyl-2-methoxy-3-(m...)
Affinity DataIC50: 18.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277694BDBM277694(US10072034, Example 20(a) | US10072034, Example 20...)
Affinity DataIC50: 19.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277679BDBM277679(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-(methoxy-d...)
Affinity DataIC50: 19.5nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 50169048BDBM50169048((R)-2-(3-Benzoylphenyl)propionic acid | (R)-2-(3-b...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 50295270BDBM50295270(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2-hydro...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 277703BDBM277703(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 20.6nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277681BDBM277681(2-(2-(2-(3-(4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(...)
Affinity DataIC50: 20.8nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277676BDBM277676(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 24.6nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 50090679BDBM50090679([2-(2,5-Dichloro-phenylamino)-phenyl]-acetic acid ...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 50295269BDBM50295269(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N,N'-[3,3-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 277700BDBM277700(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)
Affinity DataIC50: 26.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277684BDBM277684(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(dimethylp...)
Affinity DataIC50: 26.5nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277698BDBM277698(N-(3-(3-(4-((2-((3-(2-(2-(1H-Tetrazol-5-yl)methoxy...)
Affinity DataIC50: 29.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 277692BDBM277692(N-(5-(tert-Butl-2-methoxy-3-(3-(4-((2-((3-methoxy-...)
Affinity DataIC50: 29.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 50295283BDBM50295283(2-[2-(2-Fluorophenoxy)phenyl]-N-(methylsulfonyl)ac...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 50169044BDBM50169044((2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid | ...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 277699BDBM277699(2-(2-(3-((4-((4-(3-(5-(tert-Buty-2-methoxy-3-(meth...)
Affinity DataIC50: 61.9nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 50295287BDBM50295287(2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...)
Affinity DataIC50: 90nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 277678BDBM277678(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 115nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
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LigandChemical structure of BindingDB Monomer ID 50295275BDBM50295275([2-(2-Chloro-phenylamino)-phenyl]-acetic acid | 2-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 50295274BDBM50295274(2-(2-(2,6-dichloro-3-methylphenylamino)phenyl)acet...)
Affinity DataIC50: 500nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
Entry Details Article
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LigandChemical structure of BindingDB Monomer ID 50295282BDBM50295282([2-(2-Chloro-phenoxy)-phenyl]-acetic acid | 2-(2-(...)
Affinity DataIC50: 500nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 59542BDBM59542(SMR000523991 | cid_1088438 | MLS001201458 | 1-(4-m...)
Affinity DataIC50: 551nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2011
Entry Details
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LigandChemical structure of BindingDB Monomer ID 59542BDBM59542(SMR000523991 | cid_1088438 | MLS001201458 | 1-(4-m...)
Affinity DataIC50: 596nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2011
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LigandChemical structure of BindingDB Monomer ID 50295271BDBM50295271(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2,6-dim...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
Entry Details Article
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LigandChemical structure of BindingDB Monomer ID 50295272BDBM50295272(N-(tert-Butyl)-2-{2-[(2,6-dichlorophenyl)amino]phe...)
Affinity DataIC50: 650nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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Date in BDB:
8/26/2010
Entry Details Article
PubMed
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LigandChemical structure of BindingDB Monomer ID 50295273BDBM50295273(3-(2-(2-(2,6-dichlorophenylamino)phenyl)propanamid...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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