Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat brainMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.643nMAssay Description:Displacement of [3H]SCH-23390 from dopamine D1 receptor in rat brainMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat brainMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 6.09nMAssay Description:Displacement of [3H]ketanserin from rat cloned 5HT2A receptor expressed in NIH-3T3-GF6 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 9.40nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat brainMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat brainMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 13.6nMAssay Description:Displacement of [3H]ketanserin from rat cloned 5HT2A receptor expressed in NIH-3T3-GF6 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 21.1nMAssay Description:Displacement of [3H]ketanserin from rat cloned 5HT2A receptor expressed in NIH-3T3-GF6 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 21.1nMAssay Description:Displacement of [3H]ketanserin from rat cloned 5HT2A receptor expressed in NIH-3T3-GF6 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat brainMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Displacement of [3H]SCH-23390 from dopamine D1 receptor in rat brainMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 92nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat brainMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 425nMAssay Description:Displacement of [3H]SCH-23390 from dopamine D1 receptor in rat brainMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 2.25E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.17E+4nM ΔG°: -28.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 1.17E+4nM ΔG°: -28.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 1.23E+4nM ΔG°: -28.0kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 1.29E+4nM ΔG°: -27.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 1.62E+4nM ΔG°: -27.3kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 1.81E+4nM ΔG°: -27.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 2.28E+4nM ΔG°: -26.5kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 2.56E+4nM ΔG°: -26.2kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 2.87E+4nM ΔG°: -25.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 3.23E+4nM ΔG°: -25.6kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 5.45E+4nM ΔG°: -24.3kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 9.08E+4nM ΔG°: -23.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+5nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat brainMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+5nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.03E+5nM ΔG°: -22.8kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 3.88E+5nM ΔG°: -19.5kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 4.74E+5nM ΔG°: -19.0kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 5.48E+5nM ΔG°: -18.6kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
Affinity DataKi: 1.09E+6nM ΔG°: -16.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.11E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.12E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.13E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.18E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.18E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.20E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.20E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.22E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.26E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.32E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.32E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.33E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.37E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataKi: 1.41E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair