Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50001786
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 368203BDBM368203(US10227334, Example (S)-3-(3-Hydroxyphenyl)-4-meth...)
Affinity DataIC50: 0.100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368807BDBM50368807(CHEMBL4164869)
Affinity DataIC50: 0.100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368871BDBM50368871(CHEMBL4171332)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368817BDBM50368817(CHEMBL4171078)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368793BDBM50368793(CHEMBL4174789)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368862BDBM50368862(CHEMBL4176563)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368873BDBM50368873(CHEMBL4164447)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368804BDBM50368804(CHEMBL4163162)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368865BDBM50368865(CHEMBL4175085)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368864BDBM50368864(CHEMBL4168008)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368809BDBM50368809(CHEMBL4163562)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368868BDBM50368868(CHEMBL4167575)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368870BDBM50368870(CHEMBL4161695)
Affinity DataIC50: 0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368863BDBM50368863(CHEMBL4169918)
Affinity DataIC50: 0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368872BDBM50368872(CHEMBL4175179)
Affinity DataIC50: 0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 368200BDBM368200(3-(3-Hydroxyphenyl)-4-methyl-2-(4-(2-(3-methylazet...)
Affinity DataIC50: 0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368867BDBM50368867(CHEMBL4160734)
Affinity DataIC50: 0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368813BDBM50368813(CHEMBL4169627)
Affinity DataIC50: 0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368861BDBM50368861(CHEMBL4161455)
Affinity DataIC50: 0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368869BDBM50368869(CHEMBL4167152)
Affinity DataIC50: 0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368808BDBM50368808(CHEMBL4169959)
Affinity DataIC50: 0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368805BDBM50368805(CHEMBL4162508)
Affinity DataIC50: 0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368794BDBM50368794(CHEMBL4165638)
Affinity DataIC50: 0.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368796BDBM50368796(CHEMBL4175025)
Affinity DataIC50: 0.700nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 368202BDBM368202(US10227334, Example 2-(4-((S)-2-(azetidin-1-yl)pro...)
Affinity DataIC50: 0.900nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368812BDBM50368812(CHEMBL4159900)
Affinity DataIC50: 1.40nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368811BDBM50368811(CHEMBL4170549)
Affinity DataIC50: 1.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 368203BDBM368203(US10227334, Example (S)-3-(3-Hydroxyphenyl)-4-meth...)
Affinity DataIC50: 2.80nMAssay Description:Binding affinity to ERalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368865BDBM50368865(CHEMBL4175085)
Affinity DataIC50: 5.10nMAssay Description:Binding affinity to ERalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368800BDBM50368800(CHEMBL4173984)
Affinity DataIC50: 5.70nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368866BDBM50368866(CHEMBL4159656)
Affinity DataIC50: 9.70nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368866BDBM50368866(CHEMBL4159656)
Affinity DataIC50: 136nMAssay Description:Binding affinity to ERalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed