Compile Data Set for Download or QSAR
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Found 95 Enz. Inhib. hit(s) with all data for entry = 10660
LigandPNGBDBM557721((1S,3'R,6'R,7'R,11'S,12'R)-7'-((2r,3aR,6aS)- 5-ace...)
Affinity DataIC50:  0.0980nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557798((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (di...)
Affinity DataIC50:  0.152nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557787((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (di...)
Affinity DataIC50:  0.175nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557796((1S,3'R,6'R,7'S,11'S,12'S)-6-chloro-7'-(cis-5- (di...)
Affinity DataIC50:  0.184nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557721((1S,3'R,6'R,7'R,11'S,12'R)-7'-((2r,3aR,6aS)- 5-ace...)
Affinity DataIC50:  0.194nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557778((1S,3'R,6'S,7'S,12'R)-6-chloro-7'-(cis-5- (dimethy...)
Affinity DataIC50:  0.196nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557776((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- ((2...)
Affinity DataIC50:  0.217nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557740((1S,3'R,6'R,7'S,11'S,12'R)-7'-((2r,3aR,6aS)-5- ace...)
Affinity DataIC50:  0.217nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557747(US11364248, Example 43)
Affinity DataIC50:  0.251nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557725((1S,3'R,6'R,7'S,11'S,12'R)-7'-(cis-5-(1- azetidiny...)
Affinity DataIC50:  0.261nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557756((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50:  0.267nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557715((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(trans- 5-h...)
Affinity DataIC50:  0.290nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557802((1S,3′R,6′R,7′S,8′E,11R...)
Affinity DataIC50:  0.308nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557764((1S,3′R,6′R,7′S,11′S,12...)
Affinity DataIC50:  0.319nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557789((1S,3'R,6'R,7'S,10'S,11'S)-6-chloro-7'-(cis-5- (di...)
Affinity DataIC50:  0.331nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557750(US11364248, Example 46)
Affinity DataIC50:  0.340nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557772((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50:  0.347nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557731((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(trans- 5-(...)
Affinity DataIC50:  0.370nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557735((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (3,...)
Affinity DataIC50:  0.374nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557740((1S,3'R,6'R,7'S,11'S,12'R)-7'-((2r,3aR,6aS)-5- ace...)
Affinity DataIC50:  0.375nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557784((1S,3'R,6'R,7'S,11'S,12'R)-7'-(cis-5-amino-5- (hyd...)
Affinity DataIC50:  0.382nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557715((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(trans- 5-h...)
Affinity DataIC50:  0.382nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557762((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (di...)
Affinity DataIC50:  0.439nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557724((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-11',12'- dimet...)
Affinity DataIC50:  0.444nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557786((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (di...)
Affinity DataIC50:  0.448nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557794((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (di...)
Affinity DataIC50:  0.453nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557766((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50:  0.455nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557801((1S,3′R,6′R,7′S,8′E,11R...)
Affinity DataIC50:  0.459nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557729((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'-(cis-5- met...)
Affinity DataIC50:  0.473nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557732((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(trans- 5-(...)
Affinity DataIC50:  0.477nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557713((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-11',12'- dimet...)
Affinity DataIC50:  0.490nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557756((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50:  0.490nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557754((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50:  0.492nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557774((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (cy...)
Affinity DataIC50:  0.535nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557740((1S,3'R,6'R,7'S,11'S,12'R)-7'-((2r,3aR,6aS)-5- ace...)
Affinity DataIC50:  0.537nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557715((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(trans- 5-h...)
Affinity DataIC50:  0.555nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557798((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (di...)
Affinity DataIC50:  0.557nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557776((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- ((2...)
Affinity DataIC50:  0.568nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557751(N-(cis-2-((1S,3'R,6'R,7'S,11'S,12'R)-6- chloro-11'...)
Affinity DataIC50:  0.568nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557744((1S,3'R,6'R,7'S,11'S,12'R)-7'-(cis-5-amino-5- (hyd...)
Affinity DataIC50:  0.577nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557752((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-11',12'- dimet...)
Affinity DataIC50:  0.590nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557737((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'- ((2S,4S)-4...)
Affinity DataIC50:  0.612nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557745(US11364248, Example 41 | US11364248, Example 42)
Affinity DataIC50:  0.617nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557704(US11364248, Example 1)
Affinity DataIC50:  0.627nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557722(US11364248, Example 17)
Affinity DataIC50:  0.645nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557778((1S,3'R,6'S,7'S,12'R)-6-chloro-7'-(cis-5- (dimethy...)
Affinity DataIC50:  0.657nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557784((1S,3'R,6'R,7'S,11'S,12'R)-7'-(cis-5-amino-5- (hyd...)
Affinity DataIC50:  0.704nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557728((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-11',12'- dimet...)
Affinity DataIC50:  0.709nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557760((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50:  0.742nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM557754((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50:  0.754nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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