Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 7232
Affinity DataEC50: 0.550nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (Receptor Biology) were prepared by lysing cells in ice-co...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -47.5kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Receptor Biology) were prepared by lysing cells ...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nM ΔG°: -45.7kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Receptor Biology) were prepared by lysing cells ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.03nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (Receptor Biology) were prepared by lysing cells in ice-co...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nM ΔG°: -43.7kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Receptor Biology) were prepared by lysing cells ...More data for this Ligand-Target Pair
Affinity DataKi: 9nM ΔG°: -42.7kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Receptor Biology) were prepared by lysing cells ...More data for this Ligand-Target Pair
Affinity DataKi: 43.1nM ΔG°: -39.1kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Receptor Biology) were prepared by lysing cells ...More data for this Ligand-Target Pair
Affinity DataEC50: 57.2nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (Receptor Biology) were prepared by lysing cells in ice-co...More data for this Ligand-Target Pair
Affinity DataKi: 61.6nM ΔG°: -41.2kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane protei...More data for this Ligand-Target Pair
Affinity DataEC50: 62.6nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (Receptor Biology) were prepared by lysing cells in ice-co...More data for this Ligand-Target Pair
Affinity DataKi: 75.4nM ΔG°: -37.8kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned in house) were prepared by lysing cells in ice co...More data for this Ligand-Target Pair
Affinity DataKi: 76nM ΔG°: -37.8kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned in house) were prepared by lysing cells in ice co...More data for this Ligand-Target Pair
Affinity DataKi: 178nM ΔG°: -35.8kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Receptor Biology) were prepared by lysing cells ...More data for this Ligand-Target Pair
Affinity DataKi: 203nM ΔG°: -35.5kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Receptor Biology) were prepared by lysing cells ...More data for this Ligand-Target Pair
Affinity DataEC50: 545nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (Receptor Biology) were prepared by lysing cells in ice-co...More data for this Ligand-Target Pair
Affinity DataKi: 640nM ΔG°: -32.9kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned in house) were prepared by lysing cells in ice co...More data for this Ligand-Target Pair
Affinity DataEC50: 686nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (Receptor Biology) were prepared by lysing cells in ice-co...More data for this Ligand-Target Pair
Affinity DataKi: 691nM ΔG°: -35.2kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 ug membrane protein (recombinant delta opioid recep...More data for this Ligand-Target Pair
Affinity DataKi: 1.44E+3nM ΔG°: -33.3kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane protei...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nM ΔG°: -33.1kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane protei...More data for this Ligand-Target Pair
Affinity DataKi: 1.63E+3nM ΔG°: -33.0kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane protei...More data for this Ligand-Target Pair
Affinity DataEC50: 1.67E+3nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (Receptor Biology) were prepared by lysing cells in ice-co...More data for this Ligand-Target Pair
Affinity DataEC50: 1.96E+3nMpH: 7.4 T: 2°CAssay Description:Functional [35S]GTPgammaS binding assays were conducted as follows. Kappa opioid receptor membrane solution was prepared by sequentially adding final...More data for this Ligand-Target Pair
Affinity DataKi: 2.28E+3nM ΔG°: -29.9kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned in house) were prepared by lysing cells in ice co...More data for this Ligand-Target Pair
Affinity DataKi: 2.69E+3nM ΔG°: -29.6kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned in house) were prepared by lysing cells in ice co...More data for this Ligand-Target Pair
Affinity DataKi: 3.83E+3nM ΔG°: -30.9kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane protei...More data for this Ligand-Target Pair
Affinity DataKi: 4.03E+3nM ΔG°: -30.8kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane protei...More data for this Ligand-Target Pair
Affinity DataKi: 4.45E+3nM ΔG°: -30.5kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane protei...More data for this Ligand-Target Pair
Affinity DataKi: 4.76E+3nM ΔG°: -30.4kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 ug membrane protein (recombinant delta opioid recep...More data for this Ligand-Target Pair
Affinity DataKi: 5.35E+3nM ΔG°: -28.0kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned in house) were prepared by lysing cells in ice co...More data for this Ligand-Target Pair
Affinity DataKi: 6.14E+3nM ΔG°: -27.7kJ/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned in house) were prepared by lysing cells in ice co...More data for this Ligand-Target Pair
Affinity DataKi: 8.90E+3nM ΔG°: -28.8kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 ug membrane protein (recombinant delta opioid recep...More data for this Ligand-Target Pair
Affinity DataEC50: 1.78E+4nMpH: 7.4 T: 2°CAssay Description:[35S]GTP gamma S functional assays were conducted using freshly thawed mu-receptor membranes. Assay reactions were prepared by sequentially adding th...More data for this Ligand-Target Pair
Affinity DataKi: 1.82E+4nM ΔG°: -27.1kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 ug membrane protein (recombinant delta opioid recep...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nM ΔG°: >-26.8kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 ug membrane protein (recombinant delta opioid recep...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:Functional [35S]GTPgammaS binding assays were conducted as follows. Kappa opioid receptor membrane solution was prepared by sequentially adding final...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:[35S]GTP gamma S functional assays were conducted using freshly thawed mu-receptor membranes. Assay reactions were prepared by sequentially adding th...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:Functional [35S]GTPgammaS binding assays were conducted as follows. Kappa opioid receptor membrane solution was prepared by sequentially adding final...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nM ΔG°: >-26.8kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 ug membrane protein (recombinant delta opioid recep...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:[35S]GTP gamma S functional assays were conducted using freshly thawed mu-receptor membranes. Assay reactions were prepared by sequentially adding th...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:[35S]GTP gamma S functional assays were conducted using freshly thawed mu-receptor membranes. Assay reactions were prepared by sequentially adding th...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:Functional [35S]GTPgammaS binding assays were conducted as follows. Kappa opioid receptor membrane solution was prepared by sequentially adding final...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nM ΔG°: >-26.8kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 ug membrane protein (recombinant delta opioid recep...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:Functional [35S]GTPgammaS binding assays were conducted as follows. Kappa opioid receptor membrane solution was prepared by sequentially adding final...More data for this Ligand-Target Pair
