Compile Data Set for Download or QSAR
Report error Found 1922 Enz. Inhib. hit(s) with Target = 'Translocator protein'
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.0430nMAssay Description:In vitro binding affinity for PBR (peripheral benzodiazepine receptor) in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50390853(CHEMBL2070800)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat heart incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50390841(CHEMBL2070787)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat heart incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50185958(N-(2-methoxybenzyl)-N-(4-chloro-2-phenoxyphenyl)ac...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [11C](R)-PK1119 from Sprague-Dawley rat brain PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50409614(CHEMBL5288131)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat brain cortex mitochondrial membrane by liquid scintillation spectrometer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.0726nMAssay Description:Displacement of [3H]PK11195 from rat PBR receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.0726nMAssay Description:Binding affinity to PBR in Sprague-Dawley rat mitochondrial tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50185958(N-(2-methoxybenzyl)-N-(4-chloro-2-phenoxyphenyl)ac...)
Affinity DataKi:  0.0740nMAssay Description:Displacement of [11C](R)-PK1119 from Sprague-Dawley rat brain PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50122294(N-(5-fluoro-2-phenoxyphenyl)-N-(2-(2-fluoroethoxy)...)
Affinity DataKi:  0.0780nMAssay Description:In vitro inhibition of [11C]2 binding to Peripheral benzodiazepine receptor (PBR) in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50122294(N-(5-fluoro-2-phenoxyphenyl)-N-(2-(2-fluoroethoxy)...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [11C]DAA1106 from PBR receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50229593(N-acetyl-N-(2-methoxycarbonylbenzyl)-2-phenoxyanil...)
Affinity DataKi:  0.0978nMAssay Description:Binding affinity to PBR in Sprague-Dawley rat mitochondrial tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50185959(N-(2-ethoxybenzyl)-N-(4-chloro-2-phenoxyphenyl)ace...)
Affinity DataKi:  0.0980nMAssay Description:Displacement of [11C](R)-PK1119 from Sprague-Dawley rat brain PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50118528(Ethyl-carbamic acid 5-phenyl-6-oxa-10b-aza-benzo[e...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of [3H]Ro-5-4864 binding to mitochondrial rat testis Peripheral type benzodiazepine receptor (PBR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50185959(N-(2-ethoxybenzyl)-N-(4-chloro-2-phenoxyphenyl)ace...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [11C](R)-PK1119 from Sprague-Dawley rat brain PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [11C](R)-PK1119 from Sprague-Dawley rat brain PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50118528(Ethyl-carbamic acid 5-phenyl-6-oxa-10b-aza-benzo[e...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of [3H]PK11195 binding to Peripheral type benzodiazepine receptor (PBR) in rat cortex homogenate by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50429213(CHEMBL2332262)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat kidney mitochondria after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50355785(CHEMBL1911624)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates after 90 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50355784(CHEMBL1911623)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates after 90 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50073602(CHEMBL3408973)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat kidney mitochondrial fractions incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50355781(CHEMBL1911620)
Affinity DataIC50: 0.140nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates after 90 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50253857(N-butyl-2-(5-chloro-2-(4-chlorophenyl)-1H-indol-3-...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]PK11195 from translocator protein in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50274351(2-(6,8-Dichloro-2-(4-nitrophenyl)imidazo[1,2-a]pyr...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50274351(2-(6,8-Dichloro-2-(4-nitrophenyl)imidazo[1,2-a]pyr...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50274351(2-(6,8-Dichloro-2-(4-nitrophenyl)imidazo[1,2-a]pyr...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.160nMAssay Description:In vitro inhibition of [11C]2 binding to Peripheral benzodiazepine receptor (PBR) in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [11C]DAA1106 from Sprague-Dawley rat brain PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50122295(N-(2-Fluoromethoxy-5-methoxy-benzyl)-N-(5-fluoro-2...)
Affinity DataKi:  0.170nMAssay Description:In vitro inhibition of [11C]2 binding to Peripheral benzodiazepine receptor (PBR) in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50253893(2-(5-chloro-2-(4-chlorophenyl)-1H-indol-3-yl)-N-me...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]PK11195 from translocator protein in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50255877(N-Fluoroacetyl-N-(2,5-dimethoxybenzyl)-2-phenoxyan...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]PK11195 from rat PBR receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50421113(CHEMBL2088371)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat Sprague-Dawley kidney membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50430877(CHEMBL2336480)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]-PK 11195 from TSPO in rat C6 cell lysates after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50390852(CHEMBL2070799)
Affinity DataKi:  0.180nMAssay Description:Binding affinity to rat TSPO receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50118537(Ethyl-carbamic acid 7-chloro-5-phenyl-6-oxa-10b-az...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of [3H]PK11195 binding to Peripheral type benzodiazepine receptor (PBR) in rat cortex homogenate by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.188nMAssay Description:In vitro binding affinity for PBR (peripheral benzodiazepine receptor) in monkey brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50491017(CHEMBL2377343)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50185957(N-(4-chloro-2-phenoxyphenyl)-N-(2-isopropoxybenzyl...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [11C](R)-PK1119 from Sprague-Dawley rat brain PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50390840(CHEMBL2070786)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]PK11195 from TSPO in Wistar rat heart incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50118528(Ethyl-carbamic acid 5-phenyl-6-oxa-10b-aza-benzo[e...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of [3H]PK11195 binding to mitochondrial rat testis Peripheral type benzodiazepine receptor (PBR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50266889(N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7H-pur...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [11C]PK11195 from PBR receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human TSPOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50159077(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Affinity DataKi:  0.203nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50429219(CHEMBL2332256)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat kidney mitochondria after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50421106(CHEMBL2088364)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat Sprague-Dawley kidney membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50363527(CHEMBL1945412 | US9481685, [18F]FE-PBR)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50253483(N,N-dihexyl-2-(2-(4-nitrophenyl)-1H-indol-3-yl)-2-...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]PK11195 from translocator protein in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50429217(CHEMBL2332258)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat kidney mitochondria after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50274260(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50118539(Diethyl-carbamic acid 5-thiophen-2-yl-6-oxa-10,10b...)
Affinity DataKi:  0.230nMAssay Description:Inhibition of [3H]PK11195 binding to Peripheral type benzodiazepine receptor (PBR) in rat cortex homogenate by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50491024(CHEMBL2377352)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
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