Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50007006
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human TASK1 expressed in CHO cells by Inside-out macro-patches based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Rattus norvegicus)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat TASK3 expressed in (FRT) epithelial cells by chamber based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50312105(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human TASK1 expressed in CHO cells by Qpatch HT platform based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  35nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Qpatch HT platform based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Rattus norvegicus)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50:  36nMAssay Description:Inhibition of rat TASK3 expressed in (FRT) epithelial cells by chamber based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human TASK3 expressed in CHO cells by Inside-out macro-patches based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50054472((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid ((...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human TASK1 expressed in African green monkey COS cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123508(CHEMBL148159 | [2'-(2-Pyridin-2-yl-ethylcarbamoyl)...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505292(CHEMBL4592278)
Affinity DataIC50:  220nMAssay Description:Inhibition of human TASK1 by whole cell voltage clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505292(CHEMBL4592278)
Affinity DataIC50:  222nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  243nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  300nMAssay Description:Inhibition of human TASK1 expressed in HEK293 cells by Qpatch HT platform based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50:  318nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505295(CHEMBL4468526)
Affinity DataIC50:  350nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Rattus norvegicus)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505297(CHEBI:681848 | Doxapram)
Affinity DataIC50:  410nMAssay Description:Inhibition of rat TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505299(CHEMBL1557966)
Affinity DataIC50:  413nMAssay Description:Inhibition of human TASK3 expressed in HEK293 by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50417943(CHEMBL1671897)
Affinity DataIC50:  600nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505292(CHEMBL4592278)
Affinity DataIC50:  950nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50312105(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Affinity DataIC50:  990nMAssay Description:Inhibition of human TASK3 expressed in CHO cells by Qpatch HT platform based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505294(CHEMBL4441986)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM22988((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human TASK1 expressed in African green monkey COS7 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505299(CHEMBL1557966)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human TASK1 by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 17(Homo sapiens)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human TASK4 expressed in CHO cells by Inside-out macro-patches based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 5(Homo sapiens)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human TASK2 expressed in CHO cells by Inside-out macro-patches based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Rattus norvegicus)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505297(CHEBI:681848 | Doxapram)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of rat TASK3 expressed in (FRT) epithelial cells by chamber based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM78934(2-methoxyacetic acid [(1S,2S)-2-[2-[3-(1H-benzimid...)
Affinity DataIC50:  2.46E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Rattus norvegicus)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505297(CHEBI:681848 | Doxapram)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of rat TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50225497(CHEBI:4904 | Duranest [as hydrochloride] | Etidoca...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Rattus norvegicus)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50350790(BUPIVACAINE HYDROCHLORIDE | Bupivacaine | SAMPL3, ...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of rat TASK1 expressed in African green monkey COS7 cells by outside-out patches based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50350790(BUPIVACAINE HYDROCHLORIDE | Bupivacaine | SAMPL3, ...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM79212((2R,3R)-2-(diphenylmethyl)-N-[(2-iodanylphenyl)met...)
Affinity DataIC50:  4.55E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50442906(Oligomycin)
Affinity DataIC50:  4.77E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50099963(CHEMBL30432 | N*4*-(1-Benzyl-1H-indazol-5-yl)-N*6*...)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505291(CHEMBL4564685)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50239375(CHEBI:8890 | Ropivacaine)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM22876(CHEMBL998 | Claritin | Loratadine | Sch 29851 | US...)
Affinity DataIC50:  6.34E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM22872(1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-y...)
Affinity DataIC50:  7.38E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM22872(1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-y...)
Affinity DataIC50:  7.38E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505300(CHEMBL4458347)
Affinity DataIC50:  7.38E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505298(CHEMBL4461580)
Affinity DataIC50:  8.35E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505293(CHEMBL4439787)
Affinity DataIC50:  9.67E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Rattus norvegicus)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50350790(BUPIVACAINE HYDROCHLORIDE | Bupivacaine | SAMPL3, ...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of rat TASK3 expressed in African green monkey COS7 cells by outside-out patches based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50011036((S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-...)
Affinity DataIC50:  1.59E+5nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505296(CHEMBL4521731)
Affinity DataIC50:  1.89E+5nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50017662(2-(Diethylamino)-2',6'-acetoxylidide | 2-(Diethyla...)
Affinity DataIC50:  2.22E+5nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505301(CHEMBL4466298)
Affinity DataIC50:  2.68E+5nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50017659(2-(Dimethylamino)ethyl p-(butylamino)benzoate | 2-...)
Affinity DataIC50:  6.68E+5nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50417964(Carbocaine | MEPIVACAINE)
Affinity DataIC50:  7.09E+5nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed