Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50036293
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037991(CHEMBL325166 | NAPSAGATRAN | Ro-46-6240 | {[(S)-3-...)
Affinity DataKi:  0.270nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037976(CHEMBL341260 | {Benzyl-[(S)-3-[((S)-1-carbamimidoy...)
Affinity DataKi:  0.680nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037995(CHEMBL338669 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  0.710nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037984(CHEMBL339094 | {Butyl-[(S)-3-[((S)-1-carbamimidoyl...)
Affinity DataKi:  0.860nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037983((2R,4R)-1-[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3...)
Affinity DataKi:  3.10nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037997((S)-4-Azocan-1-yl-N-(1-carbamimidoyl-piperidin-3-y...)
Affinity DataKi:  4.80nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037994((2R,4R)-1-[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3...)
Affinity DataKi:  6.70nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037992((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-3...)
Affinity DataKi:  9nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037974((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037978(CHEMBL543893 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037987((R)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-3-(1H...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037993((S)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-4-mor...)
Affinity DataKi:  19nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataKi:  20nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037974((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...)
Affinity DataKi:  31nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  32nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037982((R)-3-(4-Acetylamino-phenyl)-N-(1-carbamimidoyl-pi...)
Affinity DataKi:  38nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  47nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037977((R)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-(na...)
Affinity DataKi:  63nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037979(CHEMBL539559 | {Benzyl-[(S)-3-[((S)-1-carbamimidoy...)
Affinity DataKi:  70nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037998(CHEMBL543419 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  86nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037980(1-[(S)-3-[(1-Carbamimidoyl-piperidin-3-ylmethyl)-c...)
Affinity DataKi:  93nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037972(CHEMBL128980 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  100nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037985(CHEMBL553963 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  110nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50038000((R)-N-((R)-1-Carbamimidoyl-piperidin-3-ylmethyl)-3...)
Affinity DataKi:  130nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  150nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037976(CHEMBL341260 | {Benzyl-[(S)-3-[((S)-1-carbamimidoy...)
Affinity DataKi:  150nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...)
Affinity DataKi:  300nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037990(CHEMBL539815 | {Butyl-[(S)-3-[((S)-1-carbamimidoyl...)
Affinity DataKi:  330nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  360nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037989(CHEMBL544131 | N-(1-Carbamimidoyl-piperidin-3-ylme...)
Affinity DataKi:  480nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037999((S)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-3-(1H...)
Affinity DataKi:  660nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037994((2R,4R)-1-[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3...)
Affinity DataKi:  780nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037983((2R,4R)-1-[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3...)
Affinity DataKi:  1.10E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037988(1-[(S)-3-[(1-Carbamimidoyl-piperidin-3-ylmethyl)-c...)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037991(CHEMBL325166 | NAPSAGATRAN | Ro-46-6240 | {[(S)-3-...)
Affinity DataKi:  1.90E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037984(CHEMBL339094 | {Butyl-[(S)-3-[((S)-1-carbamimidoyl...)
Affinity DataKi:  3.10E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037995(CHEMBL338669 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  3.80E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037980(1-[(S)-3-[(1-Carbamimidoyl-piperidin-3-ylmethyl)-c...)
Affinity DataKi:  5.40E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037993((S)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-4-mor...)
Affinity DataKi:  7.50E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037979(CHEMBL539559 | {Benzyl-[(S)-3-[((S)-1-carbamimidoy...)
Affinity DataKi:  8.60E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037974((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  1.20E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037992((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-3...)
Affinity DataKi:  1.70E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037972(CHEMBL128980 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  2.00E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037982((R)-3-(4-Acetylamino-phenyl)-N-(1-carbamimidoyl-pi...)
Affinity DataKi:  2.00E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037978(CHEMBL543893 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  2.30E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  2.60E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037985(CHEMBL553963 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  2.70E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037999((S)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-3-(1H...)
Affinity DataKi:  2.70E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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