Compile Data Set for Download or QSAR
Report error Found 91 Enz. Inhib. hit(s) with all data for entry = 1168
TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311805BDBM311805(US10155769, Example 43 | 7-(4-Fluorophenyl)-8-(7-c...)
Affinity DataIC50: 0.0100nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311771BDBM311771(US10155769, Example 9 | 2-Cyclopentyl-7-(4-fluorop...)
Affinity DataIC50: 0.0160nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311766BDBM311766(US10155769, Example 4 | 2-Cyclobutyl-7-(4-fluoroph...)
Affinity DataIC50: 0.0250nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311848BDBM311848(US10155769, Example 89 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.0250nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311806BDBM311806(US10155769, Example 44 | 7-(4-Fluorophenyl)-8-(7-m...)
Affinity DataIC50: 0.0320nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311808BDBM311808(US10155769, Example 46 | 2-(Difluoromethyl)-7-(4-f...)
Affinity DataIC50: 0.0320nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311811BDBM311811(US10155769, Example 49 | 7-Isopropyl-8-(7-methyl-1...)
Affinity DataIC50: 0.0320nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311847BDBM311847(US10155769, Example 88 | 5-(2,7-Bis(trifluoromethy...)
Affinity DataIC50: 0.0500nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311810BDBM311810(US10155769, Example 48 | 2-Cyclopropyl-7-(4-fluoro...)
Affinity DataIC50: 0.0790nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311768BDBM311768(US10155769, Example 6 | 7-Cyclopentyl-8-(7-methyl-...)
Affinity DataIC50: 0.0790nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311828BDBM311828(US10155769, Example 66 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.100nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311849BDBM311849(US10155769, Example 90 | 2-Isopropyl-8-(7-methyl-1...)
Affinity DataIC50: 0.100nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311843BDBM311843(US10155769, Example 81 | 3-Chloro-8-(7-chloro-1H-i...)
Affinity DataIC50: 0.126nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311829BDBM311829(US10155769, Example 67 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.126nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311799BDBM311799(US10155769, Example 37 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.126nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311792BDBM311792(US10155769, Example 30 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.158nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311845BDBM311845(US10155769, Example 86 | 5-(2,7-Bis(trifluoromethy...)
Affinity DataIC50: 0.158nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311833BDBM311833(US10155769, Example 71 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.158nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311793BDBM311793(US10155769, Example 31 | 2-Cyclopropyl-8-(7-methyl...)
Affinity DataIC50: 0.200nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311830BDBM311830(US10155769, Example 68 | 2-Cyclopropyl-8-(7-methyl...)
Affinity DataIC50: 0.251nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311781BDBM311781(US10155769, Example 19 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.251nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311767BDBM311767(US10155769, Example 5 | 6-(7-(4-Fluorophenyl)-2-(t...)
Affinity DataIC50: 0.251nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311850BDBM311850(US10155769, Example 91 | 2-Cyclopropyl-8-(7-methyl...)
Affinity DataIC50: 0.251nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311824BDBM311824(US10155769, Example 62 | 5-(2,7-Bis(trifluoromethy...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311775BDBM311775(US10155769, Example 13 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311844BDBM311844(US10155769, Example 82 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311754BDBM311754(US10155769, Example 1 | 8-(7-Chloro-1H-indazol-5-y...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311783BDBM311783(US10155769, Example 21 | 5-(2,7-Bis(trifluoromethy...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311831BDBM311831(US10155769, Example 69 | 7-Chloro-5-[2-cyclopropyl...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311834BDBM311834(US10155769, Example 72 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311769BDBM311769(US10155769, Example 7 | 7-(Azetidin-1-yl)-8-(7-met...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311851BDBM311851(US10155769, Example 92 | 2-Ethyl-8-(7-methyl-1H-in...)
Affinity DataIC50: 0.398nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311776BDBM311776(US10155769, Example 14 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.398nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311796BDBM311796(US10155769, Example 34 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.398nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311846BDBM311846(US10155769, Example 87 | 5-(2,7-Bis(trifluoromethy...)
Affinity DataIC50: 0.398nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311785BDBM311785(US10155769, Example 23 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.398nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311852BDBM311852(US10155769, Example 93 | 2-(Difluoromethyl)-8-(7-m...)
Affinity DataIC50: 0.501nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311826BDBM311826(US10155769, Example 64 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.501nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311782BDBM311782(US10155769, Example 20 | 8-(7-Methyl-1H-indazol-5-...)
Affinity DataIC50: 0.501nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311787BDBM311787(US10155769, Example 25 | 7-Chloro-5-(7-(difluorome...)
Affinity DataIC50: 0.631nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311842BDBM311842(US10155769, Example 80 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.631nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311786BDBM311786(US10155769, Example 24 | 8-(7-Methyl-1H-indazol-5-...)
Affinity DataIC50: 0.631nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311801BDBM311801(US10155769, Example 39 | 5-[2-Isopropyl-7-(trifluo...)
Affinity DataIC50: 0.631nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311835BDBM311835(US10155769, Example 73 | 8-(7-Chloro-1H-indazol-5-...)
Affinity DataIC50: 0.794nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311790BDBM311790(US10155769, Example 28 | 7-Ethyl-8-(7-methyl-1H-in...)
Affinity DataIC50: 0.794nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311784BDBM311784(US10155769, Example 22 | 5-(2,7-Bis(trifluoromethy...)
Affinity DataIC50: 0.794nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311788BDBM311788(US10155769, Example 26 | 7-Methyl-5-(7-(difluorome...)
Affinity DataIC50: 1nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311804BDBM311804(US10155769, Example 42 | 7-(4-Fluorophenyl)-8-(7-f...)
Affinity DataIC50: 1nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311803BDBM311803(US10155769, Example 41 | 7-Chloro-8-(7-chloro-1H-i...)
Affinity DataIC50: 1nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311822BDBM311822(US10155769, Example 60 | 7-Chloro-8-(7-methyl-1H-i...)
Affinity DataIC50: 1nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

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