Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 3168
TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393445BDBM393445(US9963453, 4 | 2-(azepan-1- yl)-1-(3,4- dihydro- p...)
Affinity DataKi:  10.2nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393458BDBM393458(US9963453, 17 | 3-(azepan-1- yl)-1-(3,4- dihydro- ...)
Affinity DataKi:  10.9nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393447BDBM393447(US9963453, 6 | 2-(4-benzyl- piperidin- 1-yl)-1-(3,...)
Affinity DataKi:  14.4nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393453BDBM393453(US9963453, 12 | 2-(azepan-1- yl)-1-(8- fluoro-3,4-...)
Affinity DataKi:  14.6nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393461BDBM393461(US9963453, 21 | 4-(azepan-1- yl)-1-(8- fluoro-3,4-...)
Affinity DataKi:  21.9nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393457BDBM393457(US9963453, 16 | 1-(8-fluoro- 3,4- dihydro- pyrazin...)
Affinity DataKi:  22.2nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393455BDBM393455(US9963453, 14 | 1-(10-methyl- 3,4- dihydro- pyrazi...)
Affinity DataKi:  24nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393448BDBM393448(US9963453, 7 | 2-(azepan-1- yl)-1-(3,4- dihydro- p...)
Affinity DataKi:  24.8nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393451BDBM393451(US9963453, 10 | 2-(4- benzyl- piperidin-1-yl)- 1-(...)
Affinity DataKi:  25nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393466BDBM393466(US9963453, 27 | 2-(4- cyclohexyl- piperazin-1- yl)...)
Affinity DataKi:  25.6nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393456BDBM393456(US9963453, 15 | 2-(4- benzyl- piperidin- 1-yl)-1- ...)
Affinity DataKi:  26.2nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393460BDBM393460(US9963453, 20 | 1-(3,4- dihydro- pyrazino[1,2- a]i...)
Affinity DataKi:  28.8nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393448BDBM393448(US9963453, 7 | 2-(azepan-1- yl)-1-(3,4- dihydro- p...)
Affinity DataKi:  29.6nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393463BDBM393463(US9963453, 24 | 2-(4- cyclohexyl- piperazin-1- yl)...)
Affinity DataKi:  37.6nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393446BDBM393446(US9963453, 5 | 1-(3,4- dihydro- pyrazino[1,2- a]in...)
Affinity DataKi:  39.8nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393479BDBM393479(US9963453, 47 | (R)-1-(3,4- dihydro- pyrazino[1,2-...)
Affinity DataKi:  49.5nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393459BDBM393459(US9963453, 19 | (S)-1-(3,4- dihydro- pyrazino[1,2-...)
Affinity DataKi:  55.9nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393471BDBM393471(US9963453, 34 | (S)-2-(4- methyl- piperazin-1- yl)...)
Affinity DataKi:  56.5nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393483BDBM393483(US9963453, 51 | (R)-2-(4- cyclohexyl- piperazin-1-...)
Affinity DataKi:  59.9nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393452BDBM393452(US9963453, 11 | 1-(3,4- dihydro- pyrazino[1,2- a]i...)
Affinity DataKi:  60.8nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393444BDBM393444(US9963453, 3 | 1-(3,4- dihydro- pyrazino[1,2- a]in...)
Affinity DataKi:  68.2nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393454BDBM393454(US9963453, 13 | 2-(azepan-1- yl)-1-(8- methyl-3,4-...)
Affinity DataKi:  69.7nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393486BDBM393486(US9963453, 54 | (R)-2-(4- cyclohexyl- piperazin-1-...)
Affinity DataKi:  71.6nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393475BDBM393475(US9963453, 41 | 1-(3,4- dihydro- pyrazino[1,2- a]i...)
Affinity DataKi:  73nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393478BDBM393478(US9963453, 46 | (S)-1-(3,4- dihydro- pyrazino[1,2-...)
Affinity DataKi:  75.5nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393470BDBM393470(US9963453, 33 | (S)-2-(4- methyl- piperazin-1- yl)...)
Affinity DataKi:  84.3nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393473BDBM393473(US9963453, 38 | 1-(3,4- dihydro- pyrazino[1,2- a]i...)
Affinity DataKi:  89.3nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393481BDBM393481(US9963453, 49 | (S)-1-(3,4- dihydro- pyrazino[1,2-...)
Affinity DataKi:  91.7nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393485BDBM393485(US9963453, 53 | (S)-2-(4- cyclohexyl- piperazin-1-...)
Affinity DataKi:  94.7nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393443BDBM393443(US9963453, 2 | 1-(3,4- dihydro- pyrazino[1,2- a]in...)
Affinity DataKi:  96.1nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393442BDBM393442(US9963453, 1 | 1-(3,4- dihydro- pyrazino[1,2- a]in...)
Affinity DataKi:  105nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393442BDBM393442(US9963453, 1 | 1-(3,4- dihydro- pyrazino[1,2- a]in...)
Affinity DataKi:  118nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393465BDBM393465(US9963453, 26 | 1-(8-fluoro- 3,4- dihydro- pyrazin...)
Affinity DataKi:  123nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393467BDBM393467(US9963453, 29 | 2-(4- ethylpiperazin- 1-yl)-1-(8- ...)
Affinity DataKi:  125nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393450BDBM393450(US9963453, 9 | 1-(3,4- dihydro- pyrazino[1,2- a]in...)
Affinity DataKi:  129nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393484BDBM393484(US9963453, 52 | (S)-2-(4- cyclohexyl- piperazin-1-...)
Affinity DataKi:  142nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393480BDBM393480(US9963453, 48 | (S)-1-(3,4- dihydro- pyrazino[1,2-...)
Affinity DataKi:  142nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393476BDBM393476(US9963453, 43 | 4-(dimethyl- amino)-1- (3,4,10,10a...)
Affinity DataKi:  151nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393477BDBM393477(US9963453, 44 | 2-methyl-2- (4-methyl- piperazin-1...)
Affinity DataKi:  175nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393469BDBM393469(US9963453, 32 | (R)-2-(4- methyl- piperazin-1- yl)...)
Affinity DataKi:  234nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393468BDBM393468(US9963453, 30 | 2-(2- (diethylamino) ethylamino)- ...)
Affinity DataKi:  241nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393482BDBM393482(US9963453, 50 | (R)-1-(3,4- dihydro- pyrazino[1,2-...)
Affinity DataKi:  251nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393462BDBM393462(US9963453, 22 | 1-(3,4- dihydro- pyrazino[1,2- a]i...)
Affinity DataKi:  292nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393474BDBM393474(US9963453, 39 | 1-(3,4- dihydro- pyrazino[1,2- a]i...)
Affinity DataKi:  427nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 393472BDBM393472(US9963453, 37 | 2-(1,4'- bipiperidin-1'- yl)-1-(3,...)
Affinity DataKi:  500nMAssay Description:To investigate binding properties of sigma 1 receptor ligands to human sigma 1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent