Compile Data Set for Download or QSAR
Report error Found 165 of affinity data for UniProtKB/TrEMBL: Q9Y616
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560885(CHEMBL4788568)
Affinity DataIC50: 4nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560889(CHEMBL4763746)
Affinity DataIC50: 4nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560888(CHEMBL4749646)
Affinity DataIC50: 5nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560900(CHEMBL4777817)
Affinity DataIC50: 6nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560886(CHEMBL4744403)
Affinity DataIC50: 6nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560887(CHEMBL4798668)
Affinity DataIC50: 6nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560901(CHEMBL4779593)
Affinity DataIC50: 10nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50246763(CHEMBL4094760)
Affinity DataIC50: 10nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataKd:  11nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  13nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560904(CHEMBL4791281)
Affinity DataIC50: 13nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  13nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560899(CHEMBL4754560)
Affinity DataIC50: 15nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  16nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  16nMAssay Description:Binding affinity to IRAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560898(CHEMBL4779139)
Affinity DataIC50: 19nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560902(CHEMBL4757434)
Affinity DataIC50: 21nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560905(CHEMBL4747690)
Affinity DataIC50: 21nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560890(CHEMBL4762658)
Affinity DataIC50: 21nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560903(CHEMBL4746543)
Affinity DataIC50: 22nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560896(CHEMBL4763804)
Affinity DataIC50: 24nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560897(CHEMBL4787051)
Affinity DataIC50: 25nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50246769(CHEMBL4064608)
Affinity DataIC50: 27nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50466824(CHEMBL4278882)
Affinity DataIC50: 31nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd:  31nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560895(CHEMBL4753038)
Affinity DataIC50: 33nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560892(CHEMBL4752190)
Affinity DataIC50: 33nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560888(CHEMBL4749646)
Affinity DataKd:  34nMAssay Description:Displacement of polymer supported probe 25 binding to IRAK3 in human THP-1 cell lysates preincubated for 45 mins under shaking condition followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560893(CHEMBL4743058)
Affinity DataIC50: 34nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560894(CHEMBL4778668)
Affinity DataIC50: 50nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560891(CHEMBL4750934)
Affinity DataIC50: 51nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50246769(CHEMBL4064608)
Affinity DataKd:  93nMAssay Description:Binding affinity wild type human IRAK3 (V147 to E596) expressed in bacterial expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataKd:  120nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataKd:  160nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  180nMAssay Description:Binding affinity to IRAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  180nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  180nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  240nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50355504(CHEMBL1908393)
Affinity DataKd:  370nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50524287(CHEMBL4462395)
Affinity DataKd:  480nMAssay Description:Binding affinity to human wild type partial length IRAK3 (V147 to E596 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  577nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50242737((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Affinity DataKd:  610nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd:  730nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd:  730nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd:  730nMAssay Description:Binding affinity to IRAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50524287(CHEMBL4462395)
Affinity DataKd:  740nMAssay Description:Binding affinity to human IRAK3 (147 to 596 residues) expressed in bacterial expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM210300(US9546153, ex. 367)
Affinity DataIC50: 760nMAssay Description:Inhibition of human wild type partial length IRAK3 (147 to 596 residues) expressed in bacterial expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataKd:  800nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataKd:  800nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
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