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Found 134 with Last Name = 'oefner' and Initial = 'c'
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077669((S)-2-Benzyl-N-[(S)-1-((1S,2R,3S)-1-cyclohexylmeth...)
Affinity DataIC50:  0.0250nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077678((3R,4R)-3-(1,4-Dimethoxy-naphthalen-2-ylmethoxy)-4...)
Affinity DataIC50:  0.0600nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077678((3R,4R)-3-(1,4-Dimethoxy-naphthalen-2-ylmethoxy)-4...)
Affinity DataIC50:  0.0870nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077702(4-[(3S,4R,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-5...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077693((3'R,4'R)-3'-(1,4-Dimethoxy-naphthalen-2-ylmethoxy...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077699(7-((3R,4R)-4-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-...)
Affinity DataIC50:  0.670nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077692((3R,4R,5S)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(n...)
Affinity DataIC50:  0.920nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077688((3R,4R)-4-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phe...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077703(4-{2-[(3S,4R,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077704(CHEMBL31880 | Sulfuric acid mono-[(3S,4R,5R)-4-[4-...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077709(4-{2-[(3S,4R,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl...)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077695(7-((3R,4R)-4-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(naph...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077694(7-{(3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-pipe...)
Affinity DataIC50:  5.10nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077705((3S,4S,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-5-(n...)
Affinity DataIC50:  6.40nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077697(7-((3R,4R)-4-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(naph...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077707((3R,4S,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-5-(n...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077698(5-[(3R,4R)-3-(1,4-Dimethoxy-naphthalen-2-ylmethoxy...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077696(4-[2-(7-{(3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077678((3R,4R)-3-(1,4-Dimethoxy-naphthalen-2-ylmethoxy)-4...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077706(7-{(3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-pipe...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against Escherichia coli TEM-3 Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067060(CHEMBL128523 | Sodium; (1S,5R)-2-tert-butoxycarbon...)
Affinity DataIC50:  15nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077708(4-[2-(6-{(3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067058(CHEMBL338157 | Sodium; (1S,5R)-2-(3-carbamoyl-phen...)
Affinity DataIC50:  24nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067055(CHEMBL338933 | Sodium; (1S,5R)-2-[2-(4-hydroxy-phe...)
Affinity DataIC50:  25nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077682(Benzoic acid 2-{4-[(3R,4R)-3-(naphthalen-2-ylmetho...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50408523(CHEMBL2079714)
Affinity DataIC50:  27nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067053(CHEMBL127782 | Sodium; (1S,5R)-2-benzyloxycarbonyl...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against Escherichia coli TEM-3 Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067066(CHEMBL340707 | Sodium; (1S,4R,5S)-2-benzyloxycarbo...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against Escherichia coli TEM-3 Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077699(7-((3R,4R)-4-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-...)
Affinity DataIC50:  37nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067050(CHEMBL336630 | Sodium; (1S,5R)-7-oxo-2-(piperidin-...)
Affinity DataIC50:  39nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077671((3R,4R)-3-(Naphthalen-2-ylmethoxy)-4-[4-(3-phenyl-...)
Affinity DataIC50:  41nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Staphylococcus aureus)
Morphochem

LigandPNGBDBM17871((1S)-1-[5-(benzylsulfanyl)-4H-1,2,4-triazol-3-yl]-...)
Affinity DataIC50:  43.7nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067051(CHEMBL130187 | Sodium; (1S,5R)-7-oxo-2-(4-ureido-p...)
Affinity DataIC50:  48nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077690((3R,4R)-4-[4-(2-Benzyloxy-ethoxy)-phenyl]-3-(napht...)
Affinity DataIC50:  53nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067047(CHEMBL341484 | Sodium; (1S,5R)-2-[2-(2,6-dimethyl-...)
Affinity DataIC50:  55nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077679(Benzoic acid 4-[(3R,4R)-3-(naphthalen-2-ylmethoxy)...)
Affinity DataIC50:  55nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077685(3-Methoxy-benzoic acid 4-[(3R,4R)-3-(naphthalen-2-...)
Affinity DataIC50:  87nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067065(CHEMBL130854 | Sodium; (1S,5R)-2-[2-amino-2-(4-hyd...)
Affinity DataIC50:  90nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077691((3R,4R)-4-[4-(2-Benzyloxy-ethoxymethyl)-phenyl]-3-...)
Affinity DataIC50:  91nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077667((3R,4R)-4-[4-(4-Benzyloxy-butoxy)-phenyl]-3-(napht...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077693((3'R,4'R)-3'-(1,4-Dimethoxy-naphthalen-2-ylmethoxy...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077697(7-((3R,4R)-4-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067057(CHEMBL340937 | Sodium; (1S,5R)-2-((E)-3-1H-imidazo...)
Affinity DataIC50:  110nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077696(4-[2-(7-{(3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067062(CHEMBL415234 | Sodium; (1S,6R)-2-tert-butoxycarbon...)
Affinity DataIC50:  145nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067056(CHEMBL338351 | Sodium; (1S,5R)-2-(4-hydroxy-phenyl...)
Affinity DataIC50:  155nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077709(4-{2-[(3S,4R,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl...)
Affinity DataIC50:  160nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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