BindingDB PrimarySearch_ki

Found 96 with Last Name = 'hucke' and Initial = 'o'

Genome polyprotein [1027-1206,R1052K](Hepatitis C virus)
Boehringer Ingelheim (Canada)

PNG

BDBM92407(BI201335)

Ki: 0.530nM K_on: 0.000440M^-1s^-1 K_off: 8.50E+5s^-1pH: 8.0Assay Description:Kinetic analysis of NS3 inhibitor binding experiment were performed using the KinTek stopped flow instrument (SF-2005; excitation, 325 nm; and emissi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase PC cid PC sid Similars

Details Article PubMed

Genome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

PNG

BDBM92407(BI201335)

Ki: 0.970nM K_on: 0.000530M^-1s^-1 K_off: 5.40E+5s^-1pH: 8.0Assay Description:Kinetic analysis of NS3 inhibitor binding experiment were performed using the KinTek stopped flow instrument (SF-2005; excitation, 325 nm; and emissi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase PC cid PC sid Similars

Details Article PubMed

Genome polyprotein [1027-1206,R1052K](Hepatitis C virus)
Boehringer Ingelheim (Canada)

PNG

BDBM92408(NS3 protease inhibitor, analog 1)

Ki: 1.89nM K_on: 0.00220M^-1s^-1 K_off: 1.10E+6s^-1pH: 8.0Assay Description:Kinetic analysis of NS3 inhibitor binding experiment were performed using the KinTek stopped flow instrument (SF-2005; excitation, 325 nm; and emissi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid Similars

Details Article PubMed

Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50005004(CHEMBL2397309)

IC50: 22nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50005008(CHEMBL2397312)

IC50: 35nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486119(CHEMBL2204010)

IC50: 38nMAssay Description:Inhibition of HIV1 capsid protein binding to fluorescein labeled 3-(5-(3-ethyl-5-(5-methylfuran-2-yl)-1H-pyrazol-1-yl)-1-((6-oxo-1,6-dihydropyridin-3...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50005009(CHEMBL2397311)

IC50: 40nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486134(CHEMBL2204005)

IC50: 41nMAssay Description:Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly as...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486131(CHEMBL2204007)

IC50: 44nMAssay Description:Inhibition of HIV1 capsid protein binding to fluorescein labeled 3-(5-(3-ethyl-5-(5-methylfuran-2-yl)-1H-pyrazol-1-yl)-1-((6-oxo-1,6-dihydropyridin-3...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50436476(CHEMBL2397316)

IC50: 48nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486131(CHEMBL2204007)

IC50: 49nMAssay Description:Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly as...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491676(CHEMBL2387159)

IC50: 50nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50436477(CHEMBL2397315)

IC50: 53nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50005007(CHEMBL2397310)

IC50: 53nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486118(CHEMBL2204004)

IC50: 55nMAssay Description:Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly as...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486135(CHEMBL2204006)

IC50: 56nMAssay Description:Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly as...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid PDB

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486121(CHEMBL2204008)

IC50: 59nMAssay Description:Inhibition of HIV1 capsid protein binding to fluorescein labeled 3-(5-(3-ethyl-5-(5-methylfuran-2-yl)-1H-pyrazol-1-yl)-1-((6-oxo-1,6-dihydropyridin-3...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491659(CHEMBL2387165)

IC50: 60nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486120(CHEMBL2204009)

IC50: 61nMAssay Description:Inhibition of HIV1 capsid protein binding to fluorescein labeled 3-(5-(3-ethyl-5-(5-methylfuran-2-yl)-1H-pyrazol-1-yl)-1-((6-oxo-1,6-dihydropyridin-3...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486130(CHEMBL2203999)

IC50: 67nMAssay Description:Inhibition of HIV1 capsid protein binding to fluorescein labeled 3-(5-(3-ethyl-5-(5-methylfuran-2-yl)-1H-pyrazol-1-yl)-1-((6-oxo-1,6-dihydropyridin-3...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50005010(CHEMBL2397313)

IC50: 67nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486132(CHEMBL2204002)

IC50: 88nMAssay Description:Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly as...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491668(CHEMBL2387164)

IC50: 90nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50005011(CHEMBL2397303)

IC50: 100nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491667(CHEMBL2387171)

IC50: 110nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486122(CHEMBL2204003)

IC50: 120nMAssay Description:Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly as...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491675(CHEMBL2387162)

IC50: 130nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50005005(CHEMBL2397317)

IC50: 137nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Purchase CHEMBL PC cid PC sid Similars

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491656(CHEMBL2387169)

IC50: 160nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491670(CHEMBL2387170)

IC50: 160nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486128(CHEMBL2204016)

IC50: 170nMAssay Description:Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly as...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491665(CHEMBL2387158)

IC50: 180nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491662(CHEMBL2387160)

IC50: 190nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491658(CHEMBL2387167)

IC50: 210nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491672(CHEMBL2387157)

IC50: 210nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491660(CHEMBL2387163)

IC50: 220nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50436478(CHEMBL2397314)

IC50: 225nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491678(CHEMBL2387166)

IC50: 240nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486123(CHEMBL2204001)

IC50: 280nMAssay Description:Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly as...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491661(CHEMBL2387161)

IC50: 280nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491677(CHEMBL2387175)

IC50: 290nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Cytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50437045(CHEMBL2403225)

IC50: 300nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486125(CHEMBL2204013)

IC50: 360nMAssay Description:Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly as...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486129(CHEMBL2204000)

IC50: 410nMAssay Description:Inhibition of HIV1 capsid protein assembly using 5'-fluorescein-labeled (TG)25 oligonucleotide after 2 hrs by fluorometry-based capsid disassembly as...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491671(CHEMBL2387156)

IC50: 460nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Cytochrome P450 3A4(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50005011(CHEMBL2397303)

IC50: 500nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486132(CHEMBL2204002)

IC50: 550nMAssay Description:Inhibition of HIV1 capsid protein binding to fluorescein labeled 3-(5-(3-ethyl-5-(5-methylfuran-2-yl)-1H-pyrazol-1-yl)-1-((6-oxo-1,6-dihydropyridin-3...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491657(CHEMBL2387168)

IC50: 590nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50491669(CHEMBL2387155)

IC50: 630nMAssay Description:Inhibition of HIV1 capsid-nucleocapsid assembly expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Details Article PubMed

Structural capsid protein(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL

PNG

BDBM50486135(CHEMBL2204006)

IC50: 650nMAssay Description:Inhibition of HIV1 capsid protein binding to fluorescein labeled 3-(5-(3-ethyl-5-(5-methylfuran-2-yl)-1H-pyrazol-1-yl)-1-((6-oxo-1,6-dihydropyridin-3...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid PDB

Details Article PubMed

Displayed 1 to 50 (of 96 total ) | Next | Last >>

Filter my 96 hits

Targets 17▿
- Structural capsid protein 47
- Cytochrome P450 3A4 15
- Phosphatidylinositol 4-kinase beta 10
- Cytochrome P450 2D6 5
- Cytochrome P450 2C19 3
- Serine/threonine-protein kinase 17A 2
- Genome polyprotein [1027-1206,R1052K] 2
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 2
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 2
- Mitogen-activated protein kinase kinase kinase kinase 2 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1
- Mitogen-activated protein kinase kinase kinase kinase 4 1
- Cyclin-dependent kinase 9 1
- Genome polyprotein 1
- Cytochrome P450 2C9 1
- Ribosomal protein S6 kinase alpha-4 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 3 1
- ...
Publications 5▿
- Bioorg Med Chem Lett 23: 3841-7 (2013) 41
- Bioorg Med Chem Lett 23: 3396-400 (2013) 25
- Bioorg Med Chem Lett 22: 7512-7 (2012) 22
- Bioorg Med Chem Lett 23: 4132-40 (2013) 5
- J Biol Chem 286: 11434-43 (2011) 3
Institutions 1▿
- Boehringer Ingelheim (Canada) 96
Affinity: 0.53 to 3.0E+4 nM▿
- Ki 3
- IC50 93
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 2