Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50030346
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM20000(CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  135nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  178nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM20000(CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294740(3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-ph...)
Affinity DataEC50:  1.16E+3nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM20000(CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294734(3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][(1-methy...)
Affinity DataEC50:  2.78E+3nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294743([3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][2-chlor...)
Affinity DataEC50:  3.63E+3nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294742(3-Benzyl-4-(3-{[5-fluoro-2-(trifluoromethyl)benzyl...)
Affinity DataEC50:  3.65E+3nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50227159(2-(4-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294736({3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phen...)
Affinity DataEC50:  4.17E+3nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294734(3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][(1-methy...)
Affinity DataEC50:  6.00E+3nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294744(3-Benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluorometh...)
Affinity DataEC50:  6.54E+3nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294740(3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-ph...)
Affinity DataEC50:  8.32E+3nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294742(3-Benzyl-4-(3-{[5-fluoro-2-(trifluoromethyl)benzyl...)
Affinity DataEC50:  8.41E+3nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294741(3-Benzyl-4-(3-{[2-chloro-3-(trifluoromethyl)benzyl...)
Affinity DataEC50:  8.60E+3nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 9.00E+3nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM20000(CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRalpha ligand binding domain (197-447) expressed in Escherichia ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294747(3-Benzyl-8-chloro-4-(3-{[3-(trifluoromethyl)benzyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294735([3-(8-Chloro-3-phenylcinnolin-4-yl)phenyl][(1-meth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294738({3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phen...)
Affinity DataEC50:  1.02E+4nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294743([3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][2-chlor...)
Affinity DataEC50:  1.11E+4nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294736({3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phen...)
Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294748(3-Benzyl-8-chloro-4-(3-{[2-chloro-5-(trifluorometh...)
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294738({3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phen...)
Affinity DataEC50:  1.35E+4nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294740(3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-ph...)
Affinity DataIC50: 1.40E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 1.40E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRalpha ligand binding domain (197-447) expressed in Escherichia ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294746(3-Benzyl-8-chloro-4-{3-[(2-chlorobenzyl)oxy]phenyl...)
Affinity DataIC50: 1.40E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294744(3-Benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluorometh...)
Affinity DataEC50:  1.53E+4nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294741(3-Benzyl-4-(3-{[2-chloro-3-(trifluoromethyl)benzyl...)
Affinity DataEC50:  1.81E+4nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294753([3-(8-Chloro-3-phenylcinnolin-4-yl)phenyl][2-chlor...)
Affinity DataIC50: 1.90E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294737(3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294734(3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][(1-methy...)
Affinity DataIC50: 2.40E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294733(N-[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl]-N-[(1...)
Affinity DataIC50: 2.40E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294744(3-Benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluorometh...)
Affinity DataIC50: 2.40E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294736({3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phen...)
Affinity DataIC50: 3.40E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294739({3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phen...)
Affinity DataIC50: 3.80E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294742(3-Benzyl-4-(3-{[5-fluoro-2-(trifluoromethyl)benzyl...)
Affinity DataIC50: 3.80E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294738({3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phen...)
Affinity DataIC50: 3.90E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294743([3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][2-chlor...)
Affinity DataIC50: 4.00E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294756(3-Benzyl-4-{3-[(1-methyl-1H-indol-2-yl)methoxy]-ph...)
Affinity DataIC50: 4.20E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294741(3-Benzyl-4-(3-{[2-chloro-3-(trifluoromethyl)benzyl...)
Affinity DataIC50: 4.30E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294750(3-Benzyl-8-chloro-4-(3-{[5-fluoro-2-(trifluorometh...)
Affinity DataIC50: 4.40E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294745(3-Benzyl-4-[3-(benzyloxy)phenyl]-8-chlorocinnoline...)
Affinity DataIC50: 4.60E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294754(3-Benzyl-4-(3-{[5-chloro-2-(trifluoromethyl)benzyl...)
Affinity DataIC50: 5.70E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50227159(2-(4-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataIC50: 5.80E+4nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294747(3-Benzyl-8-chloro-4-(3-{[3-(trifluoromethyl)benzyl...)
Affinity DataIC50: 6.20E+4nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294735([3-(8-Chloro-3-phenylcinnolin-4-yl)phenyl][(1-meth...)
Affinity DataIC50: 6.20E+4nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294751([3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][5-fluor...)
Affinity DataIC50: 6.20E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294755(3-Benzyl-4-(3-{[2-fluoro-3-(trifluoromethyl)benzyl...)
Affinity DataIC50: 6.30E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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