Compile Data Set for Download or QSAR
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Found 10 Enz. Inhib. hit(s) with all data for entry = 50007444
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435897(2-(2-chlorophenyl)-1-((1S,3R)- 3-(hydroxymethyl)-1...)
Affinity DataEC50:  81nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435739(2-(2,6-dichlorophenyl)-1-((1S,3R)-3-(hydroxymethyl...)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435762(2-(2,6-dichlorophenyl)-1- ((1S,3R)-5-(1-ethyl-1H- ...)
Affinity DataEC50:  172nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50509507(CHEMBL4536851)
Affinity DataEC50:  18nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM436044(2-(2-chloro-4-fluorophenyl)-1- ((1S,3R)-3-(hydroxy...)
Affinity DataEC50:  540nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435987(2-(2,6-difluorophenyl)-1- ((1S,3R)-3-(hydroxymethy...)
Affinity DataEC50:  127nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM436043(2-(2-chloro-5-fluorophenyl)-1- ((1S,3R)-3-(hydroxy...)
Affinity DataEC50:  112nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435774(1-((1S,3R)-5-(1-cyclopropyl- 1H-pyrazol-4-yl)-3- (...)
Affinity DataEC50:  287nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435904(2-(2,6-dichlorophenyl)-1-((1S,3R)-3-(hydroxymethyl...)
Affinity DataEC50:  13nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435952(2-(2-chloro-6-fluorophenyl)-1-((1S,3R)-3-(hydroxym...)
Affinity DataEC50:  28nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed