Compile Data Set for Download or QSAR
Report error Found 219 Enz. Inhib. hit(s) with all data for entry = 937
LigandPNGBDBM225896(MAP15 | US9592235, Example 272 | US9855269, Compou...)
Affinity DataIC50: 6.20nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM225896(MAP15 | US9592235, Example 272 | US9855269, Compou...)
Affinity DataIC50: 6.20nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM225896(MAP15 | US9592235, Example 272 | US9855269, Compou...)
Affinity DataIC50: 6.20nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM225896(MAP15 | US9592235, Example 272 | US9855269, Compou...)
Affinity DataIC50: 6.20nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299544(US9592235, Example 314 | N-[3-(4-amino- pyrido[3,2...)
Affinity DataIC50: 7.25nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299546(US9592235, Example 316 | 3-(4-aminopyrido [3,2-d]p...)
Affinity DataIC50: 11nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299256(US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...)
Affinity DataIC50: 11.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011536(CHEMBL3262587 | US9592235, Example 184 | US9855269...)
Affinity DataIC50: 11.8nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299492(US9592235, Example 265 | 2-(4-amino- quinazolin- 6...)
Affinity DataIC50: 14.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299462(US9592235, Example 243 | 6-(amino-5-fluoro- phenyl...)
Affinity DataIC50: 16.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299383(US9592235, Example 181 | 6-(3-chloro- phenyl)pyrid...)
Affinity DataIC50: 19.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50: 45.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299537(US9592235, Example 307 | 6-(2-methyl-4- pyridyl)py...)
Affinity DataIC50: 50.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299398(US9592235, Example 191 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 58.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM225898(MAP16 | US9592235, Example 248 | US9855269, Compou...)
Affinity DataIC50: 65.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299436(US9592235, Example 225 | N6-[2-(4-fluoro- phenyl)e...)
Affinity DataIC50: 70.1nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299617(US9592235, Example 363 | 6-[3-(difluoro- methoxy)p...)
Affinity DataIC50: 71.8nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299523(US9592235, Example 297 | 6-[3-(2-pyridyl)-1- piper...)
Affinity DataIC50: 76.4nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011551(CHEMBL3262570 | US9592235, Example 268 | US9855269...)
Affinity DataIC50: 81.2nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011560(CHEMBL3262579 | US9592235, Example 187 | US9855269...)
Affinity DataIC50: 84nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299592(US9592235, Example 357 | N6-[(3-chloro- phenyl)met...)
Affinity DataIC50: 85.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM225895(MAP14 | US9592235, Example 192 | US9855269, Compou...)
Affinity DataIC50: 88.4nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299384(US9592235, Example 182 | 6-(5-chloro-2- methyl-phe...)
Affinity DataIC50: 90.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011564(CHEMBL3262583 | MAP10 | US9592235, Example 158 | U...)
Affinity DataIC50: 92.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM299619(US9592235, Example 367 | 6-(3-methoxy- phenyl) pyr...)
Affinity DataIC50: 99.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299490(US9592235, Example 263 | N-[3-(4-amino- pyrido[3,2...)
Affinity DataIC50: 107nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299488(US9592235, Example 261 | 1-[3-(4-amino- quinazolin...)
Affinity DataIC50: 136nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299582(US9592235, Example 352 | 6-(3-chloro- phenoxy) pyr...)
Affinity DataIC50: 145nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299485(US9592235, Example 258 | 6-[3-(6-methyl-2- pyridyl...)
Affinity DataIC50: 145nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299412(US9592235, Example 205 | 6-(2-methyl- 4-pyridyl) q...)
Affinity DataIC50: 148nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299494(US9592235, Example 267 | 6-(3-ethoxy- phenyl) quin...)
Affinity DataIC50: 157nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299497(US9592235, Example 270 | N6-benzylpyrido [3,2-d] p...)
Affinity DataIC50: 161nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299397(US9592235, Example 190 | 1-acetyl-N-[3- (4-amino- ...)
Affinity DataIC50: 172nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011559(CHEMBL3262578 | US9592235, Example 269 | US9855269...)
Affinity DataIC50: 174nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299618(US9592235, Example 365 | 6-(3-isoprapoxy- phenyl) ...)
Affinity DataIC50: 179nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011568(CHEMBL3262584 | US9592235, Example 186 | US9855269...)
Affinity DataIC50: 190nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299411(US9592235, Example 204 | 6-(4-pyridyl) quinazolin-...)
Affinity DataIC50: 190nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299536(US9592235, Example 306 | 6-(2-ethyl-4- pyridyl)pyr...)
Affinity DataIC50: 204nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299423(US9592235, Example 216 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 216nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299365(US9592235, Example 171 | 6-(3-chloro-5- fluoro-phe...)
Affinity DataIC50: 226nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299550(US9592235, Example 320 | 6-[3-(2-pyrrolidin- 1-yle...)
Affinity DataIC50: 226nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011558(CHEMBL3262577 | US9592235, Example 266 | US9855269...)
Affinity DataIC50: 228nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299545(US9592235, Example 315 | N-[6-(3-amino-5- fluoro-p...)
Affinity DataIC50: 232nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299563(US9592235, Example 333 | N6-[(2-fluoro- phenyl)met...)
Affinity DataIC50: 253nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011556(CHEMBL3262575 | US9592235, Example 164 | US9855269...)
Affinity DataIC50: 258nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299435(US9592235, Example 224 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 263nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299404(US9592235, Example 197 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 264nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299339(US9592235, Example 47 | N-[3-(4-aminoquinazolin-6-...)
Affinity DataIC50: 273nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299504(US9592235, Example 277 | 6-[3-[6-(dimethyl- amino)...)
Affinity DataIC50: 290nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299489(US9592235, Example 262 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 328nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

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