Compile Data Set for Download or QSAR
Report error Found 308 Enz. Inhib. hit(s) with all data for entry = 10239
TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521949BDBM521949(N-[3-[6-(difluoromethoxy)-2- methyl-3-oxo-4H-1,4- ...)
Affinity DataKi:  0.0300nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521947BDBM521947(US11155557, Example 93 | US11155557, Example 94 | ...)
Affinity DataKi:  0.0300nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521924BDBM521924(US11155557, Example 14 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0400nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521949BDBM521949(N-[3-[6-(difluoromethoxy)-2- methyl-3-oxo-4H-1,4- ...)
Affinity DataKi:  0.0500nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521949BDBM521949(N-[3-[6-(difluoromethoxy)-2- methyl-3-oxo-4H-1,4- ...)
Affinity DataKi:  0.0500nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521931BDBM521931(US11155557, Example 21 | N-[5-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0500nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521947BDBM521947(US11155557, Example 93 | US11155557, Example 94 | ...)
Affinity DataKi:  0.0500nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521924BDBM521924(US11155557, Example 14 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0500nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521947BDBM521947(US11155557, Example 93 | US11155557, Example 94 | ...)
Affinity DataKi:  0.0500nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522020BDBM522020(US11155557, Example 110 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0500nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522037BDBM522037(US11155557, Example 127 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522062BDBM522062(US11155557, Example 152 | N-[3-[5-(difluoromethoxy...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521950BDBM521950(US11155557, Example 40 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521935BDBM521935(US11155557, Example 25 | N-[3-[5-(difluoromethoxy)...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521951BDBM521951(US11155557, Example 41 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522050BDBM522050(US11155557, Example 140 | N-[1-(cyanomethyl)-3-[6-...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521922BDBM521922(US11155557, Example 12 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522051BDBM522051(US11155557, Example 142 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521949BDBM521949(N-[3-[6-(difluoromethoxy)-2- methyl-3-oxo-4H-1,4- ...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521949BDBM521949(N-[3-[6-(difluoromethoxy)-2- methyl-3-oxo-4H-1,4- ...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521949BDBM521949(N-[3-[6-(difluoromethoxy)-2- methyl-3-oxo-4H-1,4- ...)
Affinity DataKi:  0.0700nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522000BDBM522000(US11155557, Example 90 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0700nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522000BDBM522000(US11155557, Example 90 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0700nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522007BDBM522007(N-[3-[6-(difluoromethoxy)-2- methyl-3-oxo-4H-1,4- ...)
Affinity DataKi:  0.0700nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521947BDBM521947(US11155557, Example 93 | US11155557, Example 94 | ...)
Affinity DataKi:  0.0700nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521931BDBM521931(US11155557, Example 21 | N-[5-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0700nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521947BDBM521947(US11155557, Example 93 | US11155557, Example 94 | ...)
Affinity DataKi:  0.0700nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521947BDBM521947(US11155557, Example 93 | US11155557, Example 94 | ...)
Affinity DataKi:  0.0700nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521998BDBM521998(US11155557, Example 88 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521951BDBM521951(US11155557, Example 41 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522047BDBM522047(US11155557, Example 137 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522063BDBM522063(US11155557, Example 153 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521936BDBM521936(US11155557, Example 26 | N-[3-[6- (difluoromethoxy...)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522041BDBM522041(US11155557, Example 131 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521921BDBM521921(US11155557, Example 11 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522020BDBM522020(US11155557, Example 110 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521950BDBM521950(US11155557, Example 40 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522038BDBM522038(US11155557, Example 128 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521926BDBM521926(US11155557, Example 16 | N-[3-[5-(difluoromethoxy)...)
Affinity DataKi:  0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522047BDBM522047(US11155557, Example 137 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522007BDBM522007(N-[3-[6-(difluoromethoxy)-2- methyl-3-oxo-4H-1,4- ...)
Affinity DataKi:  0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522050BDBM522050(US11155557, Example 140 | N-[1-(cyanomethyl)-3-[6-...)
Affinity DataKi:  0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521922BDBM521922(US11155557, Example 12 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522051BDBM522051(US11155557, Example 142 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522051BDBM522051(US11155557, Example 142 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 522062BDBM522062(US11155557, Example 152 | N-[3-[5-(difluoromethoxy...)
Affinity DataKi:  0.100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521998BDBM521998(US11155557, Example 88 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521999BDBM521999(US11155557, Example 89 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521960BDBM521960(US11155557, Example 50 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 521921BDBM521921(US11155557, Example 11 | N-[3-[6-(difluoromethoxy)...)
Affinity DataKi:  0.100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

Displayed 1 to 50 (of 308 total ) | Next | Last >>
Jump to: