Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50033395
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344470BDBM50344470(6-(1-(8-azabicyclo[3.2.1]octan-3-yl)-3-(pyridin-4-...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344473BDBM50344473(trans-4-(4-(2,4-dihydroindeno[1,2-c]pyrazol-6-yl)-...)
Affinity DataIC50: 0.660nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344483BDBM50344483(6-(1-((3S,4S)-3-fluoropiperidin-4-yl)-3-(pyridin-4...)
Affinity DataIC50: 1.25nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344480BDBM50344480(6-(1-((3R,4R)-3-fluoropiperidin-4-yl)-3-(pyridin-4...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344464BDBM50344464(6-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)napht...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344480BDBM50344480(6-(1-((3R,4R)-3-fluoropiperidin-4-yl)-3-(pyridin-4...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344476BDBM50344476(cis-(1R,3S)-3-(4-(2,4-dihydroindeno[1,2-c]pyrazol-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344468BDBM50344468(6-(1-(piperidin-4-yl)-3-(pyridin-4-yl)-1H-pyrazol-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344472BDBM50344472(6-(1-(azepan-4-yl)-3-(pyridin-4-yl)-1H-pyrazol-4-y...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344482BDBM50344482(6-(1-((3R,4S)-4-fluoropiperidin-3-yl)-3-(pyridin-4...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344471BDBM50344471(6-(1-(piperidin-3-yl)-3-(pyridin-4-yl)-1H-pyrazol-...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344481BDBM50344481(6-(1-((3S,4R)-3-fluoropiperidin-4-yl)-3-(pyridin-4...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344477BDBM50344477(6-(1-phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,4-...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344478BDBM50344478((3R,4R)-4-(4-(2,4-dihydroindeno[1,2-c]pyrazol-6-yl...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344479BDBM50344479(7-(4-(2,4-dihydroindeno[1,2-c]pyrazol-6-yl)-3-(pyr...)
Affinity DataIC50: 5nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25652BDBM25652(4-{1-methyl-4-[4-(4-methyl-1H-pyrazol-3-yl)phenyl]...)
Affinity DataIC50: 7nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344469BDBM50344469(6-(1-(1-methylpiperidin-4-yl)-3-(pyridin-4-yl)-1H-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344455BDBM50344455(6-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,8-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344474BDBM50344474(cis-4-(4-(2,4-dihydroindeno[1,2-c]pyrazol-6-yl)-3-...)
Affinity DataIC50: 22.9nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344453BDBM50344453(7-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-4,5-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344456BDBM50344456(4-(4-(4-(2H-1,2,3-triazol-4-yl)phenyl)-1-methyl-1H...)
Affinity DataIC50: 55nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25651BDBM25651(4-{1-methyl-4-[4-(1H-pyrazol-3-yl)phenyl]-1H-pyraz...)
Affinity DataIC50: 68nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344475BDBM50344475(2-(4-(2,4-dihydroindeno[1,2-c]pyrazol-6-yl)-3-(pyr...)
Affinity DataIC50: 72.5nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344465BDBM50344465(6-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)napht...)
Affinity DataIC50: 77nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25654BDBM25654(5-[1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]-2,3-...)
Affinity DataIC50: 94nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25655BDBM25655(6-[1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]-1H-i...)
Affinity DataIC50: 139nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344463BDBM50344463(6-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-1H-i...)
Affinity DataIC50: 328nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344460BDBM50344460(4-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-1H-i...)
Affinity DataIC50: 468nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344458BDBM50344458(N-methyl-4-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4...)
Affinity DataIC50: 647nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344457BDBM50344457(4-(4-(4-(1H-pyrrol-3-yl)phenyl)-1-methyl-1H-pyrazo...)
Affinity DataIC50: 788nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344462BDBM50344462(5-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-1H-i...)
Affinity DataIC50: 861nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344452BDBM50344452(4-(4-(4-(4-ethyl-1H-pyrazol-3-yl)phenyl)-1-methyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344466BDBM50344466(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-amine | CHE...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344467BDBM50344467(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-ol | CHEMBL...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344454BDBM50344454(7-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-4,5-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344461BDBM50344461(5-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-1H-i...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344459BDBM50344459(4-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)benze...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed