Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50001712
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385806BDBM50385806(CHEMBL2041193)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385806BDBM50385806(CHEMBL2041193)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD1 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316499BDBM50316499(CHEMBL4167582)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316852BDBM50316852(CHEMBL4171446)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316816BDBM50316816(CHEMBL4161223)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316816BDBM50316816(CHEMBL4161223)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446903BDBM50446903(CHEMBL3115293)
Affinity DataIC50: 1nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD3 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321025BDBM50321025(CHEMBL4170335)
Affinity DataIC50: 1nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317545BDBM50317545(CHEMBL4173371)
Affinity DataIC50: 1nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD3 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316844BDBM50316844(CHEMBL4162417)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385806BDBM50385806(CHEMBL2041193)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD3 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317465BDBM50317465(CHEMBL4165865)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318459BDBM50318459(CHEMBL4159227)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317547BDBM50317547(CHEMBL4163812)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of PHD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 350280BDBM350280(US10208060, Example 13 | 2-(4-Hydroxy-2-oxo-1-(3'-...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318681BDBM50318681(CHEMBL4162309)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317547BDBM50317547(CHEMBL4163812)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PHD3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317468BDBM50317468(CHEMBL4169558)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318913BDBM50318913(CHEMBL4177137)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321014BDBM50321014(CHEMBL4163550)
Affinity DataIC50: 10nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317078BDBM50317078(CHEMBL4170656)
Affinity DataIC50: 12nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 242568BDBM242568(US9422240, 1-378)
Affinity DataIC50: 14nMAssay Description:Inhibition of human PHD2 expressed in 293FT cells using HIF-1 [alpha] as substrate after 20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316511BDBM50316511(CHEMBL4161082)
Affinity DataIC50: 20nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50320830BDBM50320830(CHEMBL4162965)
Affinity DataIC50: 20nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50320749BDBM50320749(CHEMBL4165493)
Affinity DataIC50: 21nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317547BDBM50317547(CHEMBL4163812)
Affinity DataIC50: 22nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50320450BDBM50320450(CHEMBL4169295)
Affinity DataIC50: 23nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318287BDBM50318287(CHEMBL4173319)
Affinity DataIC50: 61nMAssay Description:Inhibition of human PHD2 expressed in 293FT cells using HIF-1 [alpha] as substrate after 20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321026BDBM50321026(CHEMBL4172984)
Affinity DataIC50: 66nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317078BDBM50317078(CHEMBL4170656)
Affinity DataIC50: 180nMAssay Description:Inhibition of PHD3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 240926BDBM240926(US9409892, 21)
Affinity DataIC50: 240nMAssay Description:Inhibition of HIF-PHD1 (unknown origin) expressed in insect Hi5 cells using peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 118339BDBM118339(US8653111, 72)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL as substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 118339BDBM118339(US8653111, 72)
Affinity DataIC50: 450nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD3 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 118339BDBM118339(US8653111, 72)
Affinity DataIC50: 480nMAssay Description:Inhibition of PHD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316511BDBM50316511(CHEMBL4161082)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PHD3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 240926BDBM240926(US9409892, 21)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of HIF-PHD2 (unknown origin) expressed in insect Hi5 cells using peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 107704BDBM107704(US8598210, Table XV, 11 | US8598210, 119 | US87228...)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of HIF-PHD2 (unknown origin) expressed in insect Hi5 cells using peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318679BDBM50318679(CHEMBL4162752 | US10889546, Example 44)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of HIF-PHD2 (unknown origin) expressed in insect Hi5 cells using peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317247BDBM50317247(CHEMBL4173461)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of HIF-PHD2 (unknown origin) expressed in insect Hi5 cells using peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 102348BDBM102348(US8536181, A41 | US9278930, A41 | US10562854, No. ...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of HIF-PHD2 (unknown origin) expressed in insect Hi5 cells using peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 306798BDBM306798(US10149841, Compound 9)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of HIF-PHD2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317546BDBM50317546(CHEMBL4168832)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of N-terminal truncated PHD2 (unknown origin) using biotin labelled DLDLEMLAPYIPMDDDFQL as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385806BDBM50385806(CHEMBL2041193)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed