Simple Search Results

Query String: tyrphostin AG-490

lt-ag

CHEMBL56543 AG 490 BDBM4313 Tyrphostin B42 Tyrphostin deriv. 42 (2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide AG-490 Tyrphostin AG 490
Tyrphostin Ag 879 Tyrphostin Ag-879 BDBM50468261
Tyrphostin A47 BDBM4363 RG-50864 alpha-Cyano-(3,4-dihydroxy)thiocinnamide benzylidenemalononitrile (BMN) deriv. 47 AG 213 T7540 (Tyrphostin 47) CHEMBL77030 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide
US8633212, 490 US9212153, 490 BDBM113322 US10336717, Compound 490
US10172845, Example 490 US10441581, Example 490 US10144734, Example 490 US11648243, Example 490 US10881652, Example 490 BDBM305473
US10953005, Example 490 US10172851, Example 490 US10137124, Example 490 US10112942, Example 490 BDBM296755 US10555944, Example 490
BDBM169089 US9079866, 490 US9884878, Compound 490 US9745328, Compound 490
BDBM81191 US10709712, Example 490 US10245267, Example 490 US9694016, 490
BDBM71459 US9546164, 490 US9694002, 490
US8546380, 490 BDBM103389 US8633188, 490
BDBM428056 US11053244, Example 490 US10730877, Example 490 US10544143, Example 490
US11014913, Example 490 US10870641, Example 490 US10550105, Example 490 BDBM431545
BDBM158861 US10118915, Compound 490 US9682966, 490
BDBM65133 US10166249, Example 490 US9522888, 490
US9682141, 490 US11547697, Compound 490 BDBM141090
BDBM108909 US9938267, Cmpd ID 490 US8604016, 490
BDBM137403 US20250017938, Compound 001-490 US8871790, 490
BDBM273705 US10071079, Example 490 US10478424, Example 490
BDBM374338 US10246456, Example 490 US10577367, Example 490
BDBM537959 US11603523, Example 490 US11248001, Example 490
US10710986, Example 490 BDBM452352 US11555029, No. 490
US11427601, Example 490 BDBM487006 US10947252, Example 490
US12268694, Example 490 BDBM561947 US11390631, Example 490
US10577373, Compound I-490 US10508120, Compound I-490 BDBM424035 US11046698, Compound I-490
US11084800, Cpd No. 490 BDBM512258 US11708351, Compound 490
BDBM440141 US20230279020, Example 490-1a US10633389, Example 490-1a
US10647713, Compound I-490 BDBM442529 US11396508, Compound I-490
US11414431, Compound I-490 US12221453, Compound I-490 BDBM565922
US9751854, Compound I-490 BDBM338304 US9802960, Compound I-490
BDBM110937 US8614206, 490
BDBM116773 US8637532, 490
BDBM119427 US8669266, 490
BDBM133171 US8846746, 490
BDBM137897 US8871934, 490
BDBM144305 US8969336, 490
BDBM146362 US8957068, 490
BDBM171060 US9085555, 490
BDBM177124 US9120749, 490
BDBM199854 US9226922, 490
BDBM206728 US9260425, 490
BDBM207306 US9260439, 490
BDBM214404 US9283222, 490
BDBM238803 US9394297, 490
BDBM251186 US9452986, 490
BDBM253530 US9458171, 490
BDBM258021 US9493446, 490
BDBM97924 US8481536, 490
US8541572, 490 BDBM102826
US8575203, 490 BDBM105433
US8722692, 490 BDBM122051
US8846698, 490 BDBM135008
US9012443, 490 BDBM154435
US9023865, 490 BDBM157649
US9029559, 490 BDBM47350
US9302989, 490 BDBM216608
US9328096, 490 BDBM226797
US9340517, 490 BDBM232102
US9434711, 490 BDBM248577
US9718790, I-0499 BDBM183320 US9688643, I-490 US9150546, I-490
BDBM117810 US8653087, III-490
BDBM269047 US9718825, Example 490
BDBM382779 US10273259, Example 490
BDBM394842 US10307413, Compound 490
BDBM527453 US11186582, Example 490
BDBM583598 US11524959, Compound 490.
BDBM588898 US11548892, Compound 490
BDBM596893 US11596639, Example 490
BDBM603517 US11649255, Example 490
BDBM623471 US11780845, Example 490
BDBM625925 US20230322846, Example 490
BDBM630190 US20230340011, Example 490.
BDBM635041 US11814367, Compound 490
BDBM638387 US11834453, Example 490
BDBM647279 US20240025884, Example 490
BDBM650395 US20240043427, Example 490
BDBM684095 US20240218021, Example 490
BDBM687469 US20240246964, Compound 490
BDBM723911 US20250064789, Compound 490
BDBM735799 US20250129104, Compound 490
BDBM746008 US12319655, Example 490
BDBM762081 US12378224, Example 490
BDBM763445 US12384753, Example 490
US10266560, Example 490 BDBM379531
US10377770, Example 490 BDBM410657
US10479795, Example 490 BDBM421360
US10711020, Example 490 BDBM453525
US10730863, Example 490 BDBM454029
US10975056, Example 490 BDBM491507
US11174252, Compound 490 BDBM525801
US11254663, Example 490 BDBM538555
US11261186, Example 490 BDBM540554
US11286268, Compound 490 BDBM545005
US11524968, Example 490 BDBM584741
US11591336, Compound 490 BDBM596286
US11845723, Example 490 BDBM641594
US20240116946, Example 490 BDBM666457
US20240308985, Compound 490 BDBM696837
US20240316047, Example 490 BDBM697709
US20250197382, Compound 490 BDBM752224
US20250236608, Example 490 BDBM759885
US8575197, I-490 BDBM105980
US9662327, Compound 490 BDBM326904
AG-014699 Rucaparib AG-14447 BDBM50446130 RUCAPARIB CAMSYLATE
9-(4-((cyclopropylmethyl)(methyl)amino)benzyl)-2- US11161848, Compound I-490 US10399980, Compound I-490 US10189841, Compound I-490 BDBM325284
BDBM550706 US11376246, Cpd ID AG-881 US11576906, Compound AG-881 US11311527, Cpd ID AG-881
BDBM306328 US10144742, Compound I-490
BDBM307277 US10150728, Example I-490
BDBM465151 US10793563, Compound I-490
BDBM555021 US11339144, Compound I-490
BDBM727629 US20250090540, Example I-490
CHEMBL5268577 BDBM50615013 US20240109900, Example 490
US10183021, Compound I-490 BDBM321749
US10202379, Reference Example 490 BDBM346854
US10640495, Example I-490 BDBM441527
US20250163057, Compound I-490 BDBM742214
BDBM229669 US9334269, AG
2-(furan-2-ylmethylidene)propanedinitrile BDBM4278 Tyrphostin deriv. 8
2-[(4-cyanophenyl)methylidene]propanedinitrile Tyrphostin deriv. 10 BDBM4279
Tyrphostin deriv. 1 2-(pyridin-3-ylmethylidene)propanedinitrile BDBM4271
2-(1H-indol-5-ylmethylidene)propanedinitrile Tyrphostin deriv. 13 BDBM4282
2-(1H-pyrazol-5-ylmethylidene)propanedinitrile BDBM4280 Tyrphostin deriv. 11
Tyrphostin deriv. 4 BDBM4274 2-(1H-imidazol-2-ylmethylidene)propanedinitrile
Tyrphostin deriv. 5 BDBM4275 2-{[4-(methylsulfanyl)phenyl]methylidene}propanedinitrile
AG-001859 CHEMBL254841 BDBM50477796
AG-21033 CHEMBL37541 BDBM50024670
BDBM134518 US8846656, 21-AG
BDBM50098184 CHEMBL1289260 AG-26
BDBM50377863 AG-525 CHEMBL257156
BDBM50610936 ONO-AG-367
BDBM634015 US20230357139, Compound AG
US9249085, I(ag) BDBM204973
BDBM508180 US11084798, Cpd No 490 US11046691, Compound 490 1-(2-chlorophenyl)-7-cyclopropyl-4- ((2-fluoropyridin-4- yl)amino)quinazolin-2(1H)-one US11130759, Cpd. No. 490
US10946023, Compound 288 Ag 221 AG-221 Enasidenib BDBM50503251 CC-90007 Free Base
BDBM4276 Tyrphostin deriv. 6 2-[(3-fluoro-4-methoxyphenyl)methylidene]propanedinitrile
BDBM629921 US20230340011, Example 219. US20230340011, Example 490.
BDBM638178 US11834453, Example 281 US11834453, Example 490
Roche-Dataset for PDE10A, Compound 490 BDBM564176
US11292791, Example 728 US11292791, Example 490 BDBM547217
US20230348426, Example 490 US20230348426, Example 659 BDBM632220
US20250025443, Compound 479 BDBM714455 US20250025443, Example 490
US20250025443, Example 307 US20250025443, Compound 490 BDBM714273
US9546153, ex. 491 BDBM210686 US9546153, ex. 490
2-Arachidonoylglycerol, 2-AG BDBM81557
BDBM660453 US20240092799, Compound XXIX-AG
CHEMBL359634 BDBM50164080 [Ag(CN)2]-
US12325697, Compound AG-1 BDBM747339
US9890185, Example 15(ag) BDBM381043
US9890185, Example 38(ag) BDBM381110
2-(5-hydroxy-1,2,3,4-tetrahydronaphthalen-1-ylidene)propanedinitrile Tyrphostin deriv. 23 BDBM4292
Glimepiride Niddaryl Amaryl BDBM50237590 CHEBI:5383 HOE-490
BDBM276550 US10233173, Example 490 2-[[1-(4-Fluoro-2-methyl-phenyl)triazol-4-yl]methoxy]-5-methyl- US10071988, Example 490
BDBM123742 SPECS AG-690/40696769 (6)
BDBM123743 SPECS AG-690/40108589 (7)
BDBM50400617 LANSOPRAZOLE A-65006 AG-1749
BDBM4296 (2E)-2-benzoyl-3-(3,4-dihydroxyphenyl)prop-2-enenitrile Tyrphostin deriv. 29
[4-(Methylsulfinyl)Benzylidene]malononitrile Tyrphostin deriv. 12 2-[(4-methanesulfinylphenyl)methylidene]propanedinitrile BDBM4281
US9169252, 490 US9169252, 491 US9169252, 492 US9169252, 493 BDBM187947
BDBM485646 N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(4-methyl-6-(pyridin-3- yloxy)pyridin-3-yl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide US10934310, Ex # 490 US11319329, Ex # 490 US12065446, Example 490
Tyrphostin deriv. 3 N-[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]acetamide BDBM4273
US10377742, Compound 490 US9663496, Compound 490 BDBM328352 N-(1-(4- (dimethylcarbamoyl) benzyl)piperidin-4-yl)-6- (4-(4-methoxybenzoyl) piperidine-1- carbonyl)nicotinamide
US11021481, Compound I-490 US11548890, Compound I-490 BDBM500825 7-[[5-[(2S)-2- (1-hydroxy-1- methylethyl) morpholin-4- yl]-2-pyridyl]amino]- 4-(7-methylimidazo [1,2-a]pyridin- 3-yl)isoindolin- 1-one US11078201, Compound I-490
(2E)-3-(3,4-dihydroxyphenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enenitrile BDBM4295 Tyrphostin deriv. 28
BDBM4297 Tyrphostin deriv. 30 (2E)-2-[(2-chlorophenyl)carbonyl]-3-(3,4-dihydroxyphenyl)prop-2-enenitrile
BDBM4298 Tyrphostin deriv. 33 (2E)-3-(3,4-dihydroxyphenyl)-2-[(4-nitrophenyl)carbonyl]prop-2-enenitrile
BDBM4300 (2E)-3-(3,4-dihydroxyphenyl)-2-[(2,4,6-trimethylphenyl)carbonyl]prop-2-enenitrile Tyrphostin deriv. 39
BDBM4310 Tyrphostin deriv. 60 (2E)-2-cyano-N-cyclohexyl-3-(3,4-dihydroxyphenyl)prop-2-enamide
CHEMBL56731 BDBM4304 tyrphostin 1 cid_5328771 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide
Tyrphostin deriv. 71 (2E)-3-(3,4-dihydroxyphenyl)-2-(piperidin-1-ylcarbonyl)prop-2-enenitrile BDBM4421
2-[[6-(4-Fluoro-2-methoxy-phenyl)-2-oxo-3H-imidazo[4,5-b]pyridin-1- yl]methyl]benzonitrile US11207298, Example 490 US10617676, Example 490 BDBM437153
BDBM361333 US10544130, Example 490 (R)-4-(6-aminopyridin-3- yl)-N1-(piperidin-3-yl)-3- (2H-tetrazol-5- yl)benzene-1,2- disulfonamide US10221163, Example 490
US11021515, Compound 176 US10640534, Compound 176 US10682352, Compound AG120 BDBM363689 US9850277, Compound 176 US10717764, Compound 176 US11311527, Cpd ID AG-120 US11667673, Compound 176 US11376246, Cpd ID AG-120 US11576906, Compound AG-120
(2E)-N-(2-chlorophenyl)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide Tyrphostin deriv. 54 BDBM4307
BDBM4289 Tyrphostin deriv. 20 2-(5-nitro-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile
BDBM4299 CHEMBL55994 (2E)-3-(3,4-dihydroxyphenyl)-2-(thiophen-2-ylcarbonyl)prop-2-enenitrile Tyrphostin deriv. 36
BDBM4312 Tyrphostin deriv. 64 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(2,4-dimethoxyphenyl)prop-2-enamide
Tyrphostin deriv. 70 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(2,6-dimethylphenyl)prop-2-enamide BDBM4316
BDBM357739 AG-01-128/(I-202) US10214530, Example 18
(E)-3-[3,4-bis(oxidanyl)phenyl]-2-cyano-N-(3-phenylpropyl)prop-2-enamide BDBM4303 TYRPHOSTIN AG 555 (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)acrylamide Tyrphostin deriv. 46 cid_5328770 MLS000069704 SMR000058519 (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-2-propenamide (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide CHEMBL53898
(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide CHEMBL293749 Tyrphostin deriv. 52 BDBM4306
(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)prop-2-enamide Tyrphostin deriv. 56 BDBM4308 CHEMBL440298
(5,6-Dihydroxyindanylidene)malononitrile BDBM4284 Tyrphostin deriv. 15 2-(5,6-dihydroxy-2,3-dihydro-1H-inden-1-ylidene)propanedinitrile
BDBM4286 2-(4,5-dihydroxy-2,3-dihydro-1H-inden-1-ylidene)propanedinitrile (4,5-Dihydroxyindanylidene)malononitrile Tyrphostin deriv. 17
BDBM4315 Tyrphostin deriv. 68 (2E)-3-(3,4-dihydroxyphenyl)-2-[(4-phenylpiperazin-1-yl)carbonyl]prop-2-enenitrile
Tyrphostin deriv. 50 BDBM4305 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide
ethyl 2-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]-3-phenylpropanoate Tyrphostin deriv. 58 BDBM4309
BDBM489109 2-(3-(4-methyl-3- (pyridin-4- yl)phenyl)-4-(4- sulfamoylbenzyl)- 1H-pyrazol-1- yl)thiazole-4- carboxylic acid; ; US10961200, Compound 490 US11247971, Cmpd ID 490
(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]prop-2-enamide BDBM4302 Tyrphostin deriv. 44 cid_5328772
CHEMBL296407 Tyrphostin deriv. 40 benzylidenemalononitrile (BMN) deriv. 46 BDBM4301 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
Tyrphostin deriv. 62 BDBM4311 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enamide
Mitapivat Pkr-in-1 BDBM50597714 US20250051313, Compound Mitapivat Ag-348
2-arachidonoylglycerol (2-AG) CHEMBL122972 2-Arachidonoylmonoglycerol (2-AG) 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate 2-arachidonyl-glycerol BDBM26144
3-cyclopentyl-2-(1H-tetrazol-5-yl)-6- (trifluoromethyl)benzenesulfonamide US9708336, 490 BDBM262638
(5-Sulfofurfural)Sodium Salt Tyrphostin deriv. 2 BDBM4272 sodium 5-(2,2-dicyanoeth-1-en-1-yl)furan-2-sulfonate
BDBM4314 cid_1838043 Tyrphostin deriv. 66 (2E)-2-(2,3-dihydro-1H-indol-1-ylcarbonyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile
Aminoglutethimide AG, 4 Cytadren EN300-53368 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione Elipten CHEMBL488 aminoglutethimide (AG) BDBM9460 3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione
4-[[4-[[4-[[5-tert-butyl-3-(methanesulfonamido)-2-methoxy-phenyl]carbamoylamino]-1-naphthyl]oxy]-pyridyl]amino]-2-methoxy-N-[3-(1-oxo-1,4-thiazan-4-yl)propyl]benzamide US10125100, Example 17(ag) BDBM298427 US9751837, Example 17(ag) US10941115, Example 17(ag)
CHEMBL293798 2-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile BDBM4291 Tyrphostin deriv. 22 (2-Oxo-3-indolinidene)malononitrile
US10174027, Example 490 US10023570, Example 490 BDBM284477 4-(6-(3-benzyl-3,6- diazabicyclo[3.1.1]heptan- 6-yl)pyridin-3-yl)-6-(1- methyl-1H-pyrazol-4- yl)pyrazolo[1,5-a]pyridine- 3-carbonitrile
2-[(1-benzyl-2,3-dihydro-1H-indol-5-yl)methylidene]propanedinitrile Tyrphostin deriv. 14 BDBM4283 [(N-Benzyl-5-indolinyl)methylene)]malononitrile
BDBM4277 Tyrphostin deriv. 7 (3Z)-2-amino-3-(1H-indol-5-ylmethylidene)prop-1-ene-1,1,3-tricarbonitrile Indole-Containing Inhibitor 2
2-(6-{5-chloro-2-[(oxan- 4-yl)amino]pyrimidin- 4-yl}-1-oxo-2,3-dihydro- 1H-isoindol-2-yl)-N-{1- [4-(pyrimidin-5-yl)- phenyl]ethyl}acetamide US11001575, Example 490 BDBM417844 US10457669, Example 490
5-{3-fluoro-4-[4-({[5- (trifluoromethyl)pyridin-3- yl]methyl}carbamoyl)-1H-1,2,3- triazol-1-yl]butyl}-N-{[6- (trifluoromethyl)pyridin-2-yl]methyl}- 1,3,4-thiadiazole-2-carboxamide BDBM405146 US10344025, Example 490 US11370786, Example 490
CHEMBL71191 BDBM50154227 AG-1296 6,7-Dimethoxy-2-phenyl-quinoxaline 6,7-dimethoxy-2-phenylquinoxaline
Tyrphostin deriv. 25 BDBM4294 (2E)-3-(3,4-dihydroxyphenyl)-2-[(4-fluorophenyl)carbonyl]prop-2-enenitrile 3,4-Dihydroxy-a-(p-fluorobenzoyl)-cis-cinnamonitrile
2-oxo-N-(phenyl(m- tolyl)methyl)-6- (trifluoromethyl)-1,2- dihydropyridine-3- carboxamide BDBM667500 US11957687, Compound 490
2-(5-hydroxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile BDBM4287 Tyrphostin deriv. 18 (5-Hydroxy-2-oxo-3-indolinidene)malononitrile
BDBM4285 (5,6-Dihydroxy-2-oxo-3-indolinidene)malononitrile Tyrphostin deriv. 16 2-(5,6-dihydroxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile
Dimeric Tyrphostin 22 (2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxyphenyl)eth-1-ene-1-]sulfonyl}-3-(3,4-dihydroxyphenyl)prop-2-enenitrile BDBM5164
US10287301, Compound 500 1-(2-((1R,3S,4S)- 3-((6- methylpyridin-2- yl)carbamoyl)-2- azabicyclo[2.2.1] heptan-2-yl)-2- oxoethyl)-5-(6- methylpyridin-3- yl)-1H-indole-3- carboxamide BDBM386549 US10822352, Comp No. 490 US10287301, Compound 490
US10377753, Example 490 BDBM409624 2-[6-(3-Chloro-2-fluoro-phenyl)-3-fluoro-pyrrolo[3,2-b]pyridin-1-
US10253019, Example 490 2-(((3R,4S)-3-fluoro-1-(5-methyl-4H-1,2,4-triazole-3-carbonyl)piperidin-4-yl)oxy)-5-(4-((3-methyl-4-(1-methylpiperidin-4-yl)phenyl)amino)-1,3,5-triazin-2-yl)benzonitrile BDBM278268 US10040781, Example 490
(2E)-2-cyano-N-{2-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]cyclohexyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide BDBM5159 Dimeric Tyrphostin 12
BDBM5155 (2E)-2-cyano-N-{10-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]decyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide Dimeric Tyrphostin 8
BDBM5160 (2E)-2-cyano-N-{8-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]octyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide Dimeric Tyrphostin 13
4-(2,5-dichlorophenyl)-2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine BDBM353258 US9796708, Example 490
4-(3-isopropyl-2-(2-methylpyridin-4-yl)-1H-indol-5-yl)piperidin-2-one US10660877, Example 490 BDBM443902
BDBM378359 N-(1-(1-(L-alanyl)piperidin-4-yl)ethyl)-6-chloro-2-oxoindoline-5-carboxamide US10266526, Compound 490
N-(3,4-difluorophenyl)-1-[(1,2-dimethyl-1H-imidazol-5-yl)sulfonyl]-4-phenylpyrrolidin-3-amine BDBM308971 US9656955, Example 490
(2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]butyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide Dimeric Tyrphostin 4 CHEMBL144589 BDBM5151
(2E)-2-cyano-N-{6-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]hexyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide BDBM5154 Dimeric Tyrphostin 7 CHEMBL144760
(2E)-3-(3-bromo-4,5-dihydroxyphenyl)-2-{[(1E)-2-(3-bromo-4,5-dihydroxyphenyl)-1-cyanoeth-1-ene-1-]sulfonyl}prop-2-enenitrile BDBM5165 Dimeric Tyrphostin 23
CHEMBL144842 Dimeric Tyrphostin 6 BDBM5153 (2E)-2-cyano-N-{5-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]pentyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide
CHEMBL358494 (2E)-2-({4-[(2E)-2-cyano-2-[(3,4-dihydroxyphenyl)methylidene]acetyl]piperazin-1-yl}carbonyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile Dimeric Tyrphostin 15 BDBM5162
CHEMBL67535 Dimeric Tyrphostin 2 BDBM5149 (2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]propyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide
Dimeric Tyrphostin 3 (2E)-2-cyano-N-{2-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]ethyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide CHEMBL144908 BDBM5150
Dimeric Tyrphostin 5 (2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydroxyphenyl)prop-2-enamido]butyl}-3-(3,4,5-trihydroxyphenyl)prop-2-enamide BDBM5152 CHEMBL358746
N-(phenyl(m-tolyl)methyl)- 2-oxo-6-(trifluoromethyl)- 1,2-dihydropyridine-3- carboxamide BDBM667418 US11957687, Compound 20 US11957687, Compound 490
2-(6-hydroxy-5-methoxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile (5-Methoxy-6-hydroxy-2-oxo-3-indolinidene)malononitrile Tyrphostin deriv. 21 BDBM4290
BDBM4288 Tyrphostin deriv. 19 (N-Methyl-5-hydroxy-2-oxo-3-indolinidene)malononitrile 2-(5-hydroxy-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile
BDBM5157 Dimeric Tyrphostin 10 (2E)-2-cyano-N-[(3-{[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]methyl}cyclohexyl)methyl]-3-(3,4-dihydroxyphenyl)prop-2-enamide
BDBM5166 (2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxy-5-methoxyphenyl)eth-1-ene-1-]sulfonyl}-3-(3,4-dihydroxy-5-methoxyphenyl)prop-2-enenitrile Dimeric Tyrphostin 24
Dimeric Tyrphostin 1 BDBM5148 (2E)-3-(3-bromo-4,5-dihydroxyphenyl)-N-{3-[(2E)-3-(3-bromo-4,5-dihydroxyphenyl)-2-cyanoprop-2-enamido]propyl}-2-cyanoprop-2-enamide
CHEMBL166486 2-(3,4-dihydroxy-5-nitrobenzylidene)malononitrile 2-(3,4-Dihydroxy-5-nitro-benzylidene)-malononitrile AG-1288 BDBM50017871
5-[3-(2,5-dimethylfuran-3-yl)-1,2,4- oxadiazol-5-yl]-1-(propan-2-yl)-1H- 1,2,3-benzotriazole US11912693, Compound 490 BDBM654877
BDBM294934 2-(4,6-Dimethylpyrimidin-2-yl)-5-[(2-fluoro-6-pyridin-2-ylphenyl)carbonyl]octahydropyrrolo[3,4-c]pyrrole US9586962, Example 490
BDBM486280 US10941160, Example 490 N-[2-ethyl-8-(2-methyl-1-oxoisoquinolin-4-yl)- 3,4-difluoro-2H-chromen-6-yl] methanesulfonamide
US10023592, Example 490 N-[2-ethyl-8-(2-methyl-1-oxoisoquinolin-4-yl)- 3,4-dihydro-2H-chromen-6-yl] methanesulfonamide BDBM285436
US10336762, Compound 490 N-(5-aminopyridin-3- yl)-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-iso- propylamino)nicotinamide BDBM407548
US20250171431, Compound 490 1-{5-[4-(6-chloro-3- quinolylamino)-2- pyrimidinylamino]-4-methoxy-2-pyridyl}-4-methyl-4-piperidinol BDBM745173
(2E)-2-cyano-N-(2-{4-[(2E)-2-cyano-2-[(3,4-dihydroxyphenyl)methylidene]acetyl]piperazin-1-yl}ethyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide Dimeric Tyrphostin 14 BDBM5161
3,4-Dihydroxy-a-(3,4-dihydroxybenzoyl)-cis-cinnamonitrile 2-Cyano-3 ,4 -dihydroxyacetophenone (2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphenyl)carbonyl]prop-2-enenitrile cid_5328760 Tyrphostin deriv. 24 BDBM4293
CHEMBL144159 BDBM5156 Dimeric Tyrphostin 9 (2E)-2-cyano-N-[(3-{[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]methyl}phenyl)methyl]-3-(3,4-dihydroxyphenyl)prop-2-enamide
Prevacid iv BDBM50070208 Prevacid Solutab Prevacid A-65006 AG-1749 Prevacid Delayed Release CHEBI:6375 Lansoprazole Prevacid 24hr
(E)-3-(4-hydroxy-3-iodo-5-methoxy-phenyl)-2-protocatechuoyl-acrylonitrile MLS002153417 (E)-2-[(3,4-dihydroxyphenyl)-oxomethyl]-3-(4-hydroxy-3-iodo-5-methoxyphenyl)-2-propenenitrile I-OMe-Tyrphostin AG 538 SMR001230793 BDBM60983 cid_5353685 (E)-2-[3,4-bis(oxidanyl)phenyl]carbonyl-3-(3-iodanyl-5-methoxy-4-oxidanyl-phenyl)prop-2-enenitrile (E)-2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile
Preparation of 3-(phenylamino)-2-{2-[(3-phenylpropyl)amino]pyridin-4-yl}-1,5,6,7-tetrahydro-4H-indol-4-one US10428044, Example 490 BDBM415377
Dimeric Tyrphostin 21 BDBM5163 (2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(1H-indol-5-yl)prop-2-enamido]propyl}-3-(1H-indol-5-yl)prop-2-enamide
BDBM50122776 cid_9840076 CHEMBL65892 1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one AG-014361
BDBM50322367 CHEMBL1173054 5-(4-(pyrrolidin-1-ylmethyl)phenyl)-2,3,4,6-tetrahydro-1H-azepino[5,4,3-cd]indol-1-one AG-014344
US12065436, Compound 490 BDBM691101 (R)-N-(5-(5-(methoxymethyl)-1,2,4- oxadiazol-3-yl)-2,3-dihydro-1H- inden-1-yl)-1H-pyrazole-4- carboxamide
[4-(7- imidazole- 1-yl-1- methyl- [1,2,4]triazolo[4,3- a]quinoxaline- 4-ylamino)- butyl]- carbamic acid-tert- butylester US11028090, Example 490 BDBM502564
BDBM319439 US10173991, Example 490 N-[(cyclopropyl- carbamoyl) methyl]-2- (dimethyl- sulfamoyl)-2-[4- fluoro-6-(6- methypylridazin- 4-yl)-1,3- benzothiazol- 2-yl]acetamide
BDBM494434 US10988478, Example 490 6-(azetidin-3-yl)-N-(2,2- dimethyl-6-morpholino- 2,3-dihydrobenzofuran-5- yl)pyrazolo[1,5- a]pyrimidine-3- carboxamide hydrochloride
US11998539, Example 490 BDBM679048 4-{4-[5- (methoxymethyl)- 1,3-benzoxazol-2- yl]-4- methylpiperidin-1- yl}-1-methyl-2- oxo-1,2- dihydroquinoline- 3-carboxamide
BDBM293057 trans-3-(2,4-dichloro-3-((6-cyano-1,4-dimethyl-1H-indol-2-yl)methyl)phenoxy)cyclopentanecarboxylic acid US10106501, Example AG
1-[(2,5-Dimethylpyrazol-3-yl)methyl]-3-[(1-methylpyrazol-4-yl)methyl]-2,4-dioxo-N-[1-(trideuteriomethyl)cyclopropyl]quinazoline-6-sulfonamide BDBM371382 US10239843, Example 490
N-[5-[4-[[(3R)-1- methylpyrrolidin-3-yl]methoxy]- 2-propyl-pyrazol-3- yl]pyrazolo[1,5-a]pyridin-2- yl]cyclopropanecarboxamide BDBM677826 US20240174662, Example 490
US10442819, Example 490 3-{6-[(4- methoxycyclohexyl)carbonyl]-6,11- dihydro-5H-pyrido[2,3- b][1,5]benzodiazepin-8-yl}-4-methyl- 1,3-oxazolidin-2-one BDBM416346
Dimeric Tyrphostin 11 (2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(4-hydroxy-3-methoxy-5-nitrophenyl)prop-2-enamido]butyl}-3-(4-hydroxy-3-methoxy-5-nitrophenyl)prop-2-enamide BDBM5158
BDBM680275 US12011444, Example 490 2-Ethoxy-6-fluoro-4-{6-[2-(7-fluoro-4-methoxy-2-methyl-indol-1-yl)-ethylamino]- pyrimidin-4-yl}-benzoic acid
US10577363, Compound 490 N-((1R,3s,5S)-8-((6-chloro-2-oxoindolin- 5-yl)sulfonyl)-8-azabicyclo[3.2.1]octan-3- yl)-5-cyclopropylisoxazole-3-carboxamide BDBM432789
US9815796, Example 490 BDBM355399 2-[1-(4-methoxyphenyl)-1- methylethyl]-N-[(1R)-2-methyl-1- {4- [(trifluoromethyl)sulfanyl]phenyl} propyl]-6-oxo-1,6- dihydropyrimidine-4-carboxamide
BDBM537666 US11247990, Example 490 N-ethyl-1-((1s,4s)-4-(2- fluoro-3- (trifluoromethyl)phenoxy) cyclohexyl)-3- (piperazin-1-yl)-1H- pyrazolo[4,3-c]pyridin- 6-amine
6-(4-hydroxyphenethyl)-3-(4-amino-2-tert-butyl-5-methylphenylthio)-6-cyclopentyl-4-hydroxy-5,6-dihydropyran-2-one AG-21033 CHEMBL223104 BDBM50197039
{5-[(3,5-dichlorophenyl)sulfanyl]-4-(propan-2-yl)-1-(pyridin-4-ylmethyl)-1H-imidazol-2-yl}methyl carbamate AG 1549 Capravirine CPV BDBM27579
BDBM676021 3-((S)-3-((R)-8-(1H-pyrazolo[3,4-b]pyridin-5-ylsulfonyl)-1-oxa-8-azaspiro[4.5]decan-3-ylamino)-2-hydroxypropoxy)-N-methylbenzenesulfonamide US11987588, Compound 490
US20250163063, Example 490 BDBM742967 7-(sec-butyl)-6-chloro-5-fluoro-N- ((3R,4R)-3-fluoro-1- (methylsulfonyl)piperidin-4- yl)pyrrolo[2,1-f][1,2,4]triazin-2-amine
3-Amino-N-[(1R,2R)-3-(2-tert-butylcarbamoyl-phenyl)-2-hydroxy-1-(naphthalen-2-ylsulfanylmethyl)-propyl]-2-chloro-benzamide AG-1240 CHEMBL162685 BDBM50286705
5-Amino-N-[(1R,2R)-3-(2-tert-butylcarbamoyl-phenyl)-2-hydroxy-1-(naphthalen-2-ylsulfanylmethyl)-propyl]-2-methyl-benzamide AG-1256 BDBM50286701 CHEMBL164089
BDBM50286709 AG-1246 3-Amino-2-bromo-N-[(1R,2R)-3-(2-tert-butylcarbamoyl-phenyl)-2-hydroxy-1-(naphthalen-2-ylsulfanylmethyl)-propyl]-benzamide CHEMBL351819
CHEMBL128696 BDBM50061307 AG-1254 N-[(1R,2R)-3-(2-tert-Butylcarbamoyl-phenyl)-2-hydroxy-1-(naphthalen-2-ylsulfanylmethyl)-propyl]-3-hydroxy-2-methyl-benzamide
CHEMBL349200 AG-1232 3-Amino-N-[(1R,2R)-3-(2-tert-butylcarbamoyl-phenyl)-2-hydroxy-1-(naphthalen-2-ylsulfanylmethyl)-propyl]-2-methyl-benzamide BDBM50286702
CHEMBL351391 AG-1224 N-[(1R,2R)-3-(2-tert-Butylcarbamoyl-phenyl)-2-hydroxy-1-(naphthalen-2-ylsulfanylmethyl)-propyl]-2-methyl-3-nitro-benzamide BDBM50286708
CHEMBL351437 3,5-Diamino-N-[(1R,2R)-3-(2-tert-butylcarbamoyl-phenyl)-2-hydroxy-1-(naphthalen-2-ylsulfanylmethyl)-propyl]-2-methyl-benzamide BDBM50286713 AG-1282
N-[(1R,2R)-3-(2-tert-Butylcarbamoyl-phenyl)-2-hydroxy-1-(naphthalen-2-ylsulfanylmethyl)-propyl]-2-chloro-3-hydroxy-benzamide BDBM50286699 AG-1309 CHEMBL162065
N-[(1R,2R)-3-(2-tert-Butylcarbamoyl-phenyl)-2-hydroxy-1-(naphthalen-2-ylsulfanylmethyl)-propyl]-5-hydroxy-2-methyl-benzamide CHEMBL351021 AG-1273 BDBM50286706
(3R)-3-[8-amino-1-(2-fluoro-4-{[4-(trifluoromethyl)pyridin-2-yl]carbamoyl}phenyl) imidazo[1,5-a]pyrazin-3-yl]-N-cyclopropylpiperidine-1-carboxamide US9718828, Example, 490 BDBM267877
US12187709, Compound 490 6-(azepan-1-ylmethyl)-2-(3-((1r,3r)-3- methxoy-1-(4-methyl-4H-1,2,4-triazol-3- yl)cyclobutyl)phenyl)-4- (trifluoromethyl)isoindolin-1-one BDBM711131
US20240109917, Example 490 2-(2-(dimethylamino)pyridin- 4-yl)-N-(5-((2-(2,2- dimethylpyrrolidin-1- yl)ethyl)carbamoyl)-2- methylpyridin-3- yl)pyrazolo[5,1-b]thiazole-7- carboxamide BDBM664407
US20250230171, Compound 490 BDBM758968 2'-chloro-5'-methoxy-N-(5-(2- methoxypyrimidine-4-carbonyl)-5,6- dihydro-4H-pyrrolo[3,4-d]thiazol-2-yl)- 6-methyl-[4,4'-bipyridine]-3- carboxamide
(2S,3S)-2-(Acetylamino)-N-[(1S,2R)-3-[(6-benzothiazolylsulfonyl)[(2S)-2- methylbutyl]amino]-2-hydroxy-1-(phenylmethyl)propyl]-3-methyl-pentanamide (AG-23) BDBM104102
(R)-2-(4-(3-((4-methyl-4H-1,2,4-triazol- 3-yl)methyl)oxetan-3-yl)-6-(3- methylmorpholino)pyridin-2-yl)-4- (trifluoromethyl)isoindolin-1-one BDBM758309 US20250230147, Compound 490
4-acetyl-1-[3-(4-amino-5-{1H- pyrazolo[3,4-b]pyridin-5-yl}pyrrolo [2,1-f][1,2,4]triazin-7-yl)phenyl]-3,3- dimethylpiperazin-2-one US10214537, Example 490 BDBM358420
BDBM422586 3-[(S)-cyclopropyl[2- (cyclopropylmethyl)-6- hydroxy-5-[4-(1-methyl-2- oxo-1,2-dihydropyridin-3- yl)benzenesulfonyl]-4-oxo- 1,4-dihydropyrimidin-1- yl]methyl]benzonitrile US10508104, Example 490
BDBM505841 US11066414, Compound 490 (S)-1-(4-(((3,8-dicyano- 4-(neopentylamino)- quinolin-6-yl)amino)(6-fluoro-2- methylpyridin-3-yl)methyl)- 1H-1,2,3-triazol- 1-yl)cyclopropane-1-carboxamide
N-((3S,4S)-1-Acryloyl-4-methoxypyrrolidin-3-yl)-5-(*S)-(2-methyl- 4-phenoxyphenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide; US10800792, Example 490 BDBM467829
BDBM531857 1-[1-(6-{[1-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-methyl-1H-pyrazol-5-yl]amino}pyrimidin-4-yl)-3,5-dimethyl-1H-pyrazol-4-yl]propan-2-one US11208400, Example 490
US11014911, Example 490 (1R,3S)-3-(3-{[(3$#958;)-2,3- dihydro-1-benzofuran-3- ylacetyl]amino}-1H-pyrazol-5- yl)cyclopentyl [(3$#958;)-3- methyltetrahydrofuran-3- yl]carbamate - Isomer B BDBM498665
US11066396, Example 490 BDBM505095 N-({2- fluoro-4-[5- (trifluoro- methyl)- 1,2,4-oxa- diazol-3- yl]phenyl} methyl)- 1,1-dioxo- N-[3- (trifluoro- methyl) phenyl]- llambda ~6~-thiane- 4-carbox- amide
AG-028262 N-methyl-6-(2-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yloxy)benzo[b]thiophene-3-carboxamide BDBM50331091 CHEMBL1289925
AG-21541 CHEMBL222231 BDBM50197038 6-(5-chloro-2,4-dimethoxyphenethyl)-6-cyclopentyl-3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylthio)-4-hydroxy-5,6-dihydropyran-2-one
N-Cyclopropyl-3-((E)-3-((2S,6S)-2,6-dimethylmorpholino)-3-oxoprop-1-en-1-yl)-7-hydroxy-4-isobutyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamide BDBM660053 US20240092784, Example 490
BDBM399013 US10323022, Example 490 1-((3S,4R)-4-(3,4-difluorophenyl)- 1-(2-methoxyethyl)pyrrolidin-3- yl)-3-(3-(5-fluoropyridin-3-yl)-4- methyl-1-(pyridin-3-yl)-1H- pyrazol-5-yl)urea
(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-4-(phenylsulfanyl)butyl]-decahydroisoquinoline-3-carboxamide BDBM518 AG-1343 Nelfinavir Viracept CHEMBL584
(3-methyloxetan-3-yl) 3- [2-fluoro-5-[[6-oxo-4- (trifluoromethyl)-1H- pyridine-3-carbonyl]amino]- 4-[rac-(3R,5S)-3,4,5- trimethylpiperazin-1- yl]phenyl]-2,5- dihydropyrrole-1-carboxylate US11319299, Example 490 BDBM553415
US9593097, Example 490 6-[4-(5-fluoro-1H- pyrrolo[2,3- b]pyridin-3- yl)piperidin-1-yl]- N-[(2R)-1- hydroxypropan-2- yl]-2-{[(2R)-1- methoxypropan-2- yl]oxy}pyrimidine- 4-carboxamide BDBM300109
AG-013736 US9205078, Axitinib US9617222, Compound A AXITINIB US10464902, Axitinib BDBM25117 N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide US20250129067, Compound Axitinib
AG-1310 LY-309391 (3S,4aS,8aS)-2-[(2R,3S)-2-Hydroxy-3-(3-hydroxy-2-methyl-benzoylamino)-4-phenyl-butyl]-decahydro-isoquinoline-3-carboxylic acid tert-butylamide BDBM50285965 CHEMBL99607
(E)-3-(3,4-dimethoxyphenyl)-2-(3-pyridinyl)-2-propenenitrile BDBM39343 SMR000058931 TYRPHOSTIN RG 13022 MLS000028698 (E)-3-(3,4-dimethoxyphenyl)-2-pyridin-3-ylprop-2-enenitrile (E)-3-(3,4-dimethoxyphenyl)-2-(3-pyridyl)acrylonitrile (E)-3-(3,4-dimethoxyphenyl)-2-pyridin-3-yl-prop-2-enenitrile cid_5353927
BDBM673343 US20240150293, Example 490 (1r,2′S,4S)-4-(3-chloroanilino)-2′-{3-[(5-methyl-1H-indol-4-yl)oxy]propyl}-2′,3′-dihydrospiro[cyclohexane-1,1′-indene]-4-carboxylic acid
US11618753, Example 490 BDBM599347 5-{4-amino-5-[(2,6- dimethylmorpholin-4- yl)methyl]pyrrolo[2,1- f][1,2,4]triazin-7-yl}-N- [(3R,4S)-1-(3,3- difluorocyclobutanecarbonyl)- 4-fluoropyrrolidin- 3-yl]-2-methoxypyridine- 3-carboxamide, TFA
CHEMBL361489 6-(4-((dimethylamino)methyl)phenyl)-3,4-dihydro-[1,4]diazepino[6,7,1-hi]indol-1(2H)-one 6-(4-Dimethylaminomethyl-phenyl)-3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-one BDBM50154730 AG-014376
2-{[(1R)-1-(4-chlorophenyl)-7-fluoro- 5-[1-hydroxy-1-(1-methyl-1H-pyrazol- 3-yl)propyl]-3-oxo-1-[(3S)-oxolan-3- yloxy]-2,3-dihydro-1H-isoindol-2- yl]methyl}pyrimidine-5-carbonitrile BDBM535806 US11236047, Example 490