Target (18)
Compound (842)
Article Title (44)
Assay (91)
Wall, M; Shim, JH; Benkovic, SJ A multisubstrate adduct inhibitor of AICAR transformylase. J Med Chem 42: 3421 -4 (1999) Capps, KJ; Humiston, J; Dominique, R; Hwang, I; Boger, DL Discovery of AICAR Tfase inhibitors that disrupt requisite enzyme dimerization. Bioorg Med Chem Lett 15: 2840 -4 (2005) Spurr, IB; Birts, CN; Cuda, F; Benkovic, SJ; Blaydes, JP; Tavassoli, A Targeting Tumour Proliferation with a Small-Molecule Inhibitor of AICAR Transformylase Homodimerization. Chembiochem 13: 1628 -34 (2012) Boger, DL; Marsilje, TH; Castro, RA; Hedrick, MP; Jin, Q; Baker, SJ; Shim, JH; Benkovic, SJ Design, synthesis, and biological evaluation of fluoronitrophenyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase. Bioorg Med Chem Lett 10: 1471 -5 (2000) Welch, WM; Harbert, CA; Weissman, A; Koe, BK Neuroleptics from the 4a,9b-cis- and 4a,9b-trans-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole series. 2. J Med Chem 29: 2093 -9 (1986) Zimmerman, DM; Cantrell, BE; Swartzendruber, JK; Jones, ND; Mendelsohn, LG; Leander, JD; Nickander, RC Synthesis and analgesic properties of N-substituted trans-4a-aryldecahydroisoquinolines. J Med Chem 31: 555 -60 (1988) Arasappan, A; Njoroge, FG; Chen, KX; Venkatraman, S; Parekh, TN; Gu, H; Pichardo, J; Butkiewicz, N; Prongay, A; Madison, V; Girijavallabhan, V P2-P4 macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease. Bioorg Med Chem Lett 16: 3960 -5 (2006) Harper, S; McCauley, JA; Rudd, MT; Ferrara, M; DiFilippo, M; Crescenzi, B; Koch, U; Petrocchi, A; Holloway, MK; Butcher, JW; Romano, JJ; Bush, KJ; Gilbert, KF; McIntyre, CJ; Nguyen, KT; Nizi, E; Carroll, SS; Ludmerer, SW; Burlein, C; DiMuzio, JM; Graham, DJ; McHale, CM; Stahlhut, MW; Olsen, DB; Monteagudo, E; Cianetti, S; Giuliano, C; Pucci, V; Trainor, N; Fandozzi, CM; Rowley, M; Coleman, PJ; Vacca, JP; Summa, V; Liverton, NJ Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor. ACS Med Chem Lett 3: 332 -6 (2012) Passioura, T; Bhushan, B; Tumber, A; Kawamura, A; Suga, H Structure-activity studies of a macrocyclic peptide inhibitor of histone lysine demethylase 4A. Bioorg Med Chem 26: 1225 -1231 (2018) Tasker, NR; Rastelli, EJ; Burnett, JC; Sharlow, ER; Lazo, JS; Wipf, P Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors. Bioorg Med Chem Lett 29: 2008 -2015 (2019) Upadhyay, AK; Judge, RA; Li, L; Pithawalla, R; Simanis, J; Bodelle, PM; Marin, VL; Henry, RF; Petros, AM; Sun, C Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain - A fragment based approach. Bioorg Med Chem Lett 28: 1708 -1713 (2018) Liverton, NJ; Carroll, SS; Dimuzio, J; Fandozzi, C; Graham, DJ; Hazuda, D; Holloway, MK; Ludmerer, SW; McCauley, JA; McIntyre, CJ; Olsen, DB; Rudd, MT; Stahlhut, M; Vacca, JP MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease. Antimicrob Agents Chemother 54: 305 -11 (2009) Lampa, AK; Bergman, SM; Gustafsson, SS; Alogheli, H; Akerblom, EB; Lindeberg, GG; Svensson, RM; Artursson, P; Danielson, UH; Karlén, A; Sandström, A Novel Peptidomimetic Hepatitis C Virus NS3/4A Protease Inhibitors Spanning the P2-P1' Region. ACS Med Chem Lett 5: 249 -54 (2014) Zhou, Y; Bartels, DJ; Hanzelka, BL; Müh, U; Wei, Y; Chu, HM; Tigges, AM; Brennan, DL; Rao, BG; Swenson, L; Kwong, AD; Lin, C Phenotypic characterization of resistant Val36 variants of hepatitis C virus NS3-4A serine protease. Antimicrob Agents Chemother 52: 110 -20 (2008) Rudd, MT; McIntyre, CJ; Romano, JJ; Butcher, JW; Holloway, MK; Bush, K; Nguyen, KT; Gilbert, KF; Lyle, TA; Liverton, NJ; Wan, BL; Summa, V; Harper, S; Rowley, M; Vacca, JP; Carroll, SS; Burlein, C; DiMuzio, JM; Gates, A; Graham, DJ; Huang, Q; Ludmerer, SW; McClain, S; McHale, C; Stahlhut, M; Fandozzi, C; Taylor, A; Trainor, N; Olsen, DB; McCauley, JA Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2-P4 linkers. Bioorg Med Chem Lett 22: 7207 -13 (2012) Sheng, XC; Appleby, T; Butler, T; Cai, R; Chen, X; Cho, A; Clarke, MO; Cottell, J; Delaney, WE; Doerffler, E; Link, J; Ji, M; Pakdaman, R; Pyun, HJ; Wu, Q; Xu, J; Kim, CU Discovery of GS-9451: an acid inhibitor of the hepatitis C virus NS3/4A protease. Bioorg Med Chem Lett 22: 2629 -34 (2012) Salah El Dine, R; Abdel Monem, AR; El-Halawany, AM; Hattori, M; Abdel-Sattar, E HCV-NS3/4A protease inhibitory iridoid glucosides and dimeric foliamenthoic acid derivatives from Anarrhinum orientale. J Nat Prod 74: 943 -8 (2011) Shah, U; Jayne, C; Chackalamannil, S; Velázquez, F; Guo, Z; Buevich, A; Howe, JA; Chase, R; Soriano, A; Agrawal, S; Rudd, MT; McCauley, JA; Liverton, NJ; Romano, J; Bush, K; Coleman, PJ; Grisé-Bard, C; Brochu, MC; Charron, S; Aulakh, V; Bachand, B; Beaulieu, P; Zaghdane, H; Bhat, S; Han, Y; Vacca, JP; Davies, IW; Weber, AE; Venkatraman, S Novel Quinoline-Based P2-P4 Macrocyclic Derivatives As Pan-Genotypic HCV NS3/4a Protease Inhibitors. ACS Med Chem Lett 5: 264 -9 (2014) Rusere, LN; Matthew, AN; Lockbaum, GJ; Jahangir, M; Newton, A; Petropoulos, CJ; Huang, W; Kurt Yilmaz, N; Schiffer, CA; Ali, A Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants. ACS Med Chem Lett 9: 691 -696 (2018) Bennett, JM; Campbell, AD; Campbell, AJ; Carr, MG; Dunsdon, RM; Greening, JR; Hurst, DN; Jennings, NS; Jones, PS; Jordan, S; Kay, PB; O'Brien, MA; King-Underwood, J; Raynham, TM; Wilkinson, CS; Wilkinson, TC; Wilson, FX The identification of alpha-ketoamides as potent inhibitors of hepatitis C virus NS3-4A proteinase. Bioorg Med Chem Lett 11: 355 -7 (2001) Lampa, A; Alogheli, H; Ehrenberg, AE; Åkerblom, E; Svensson, R; Artursson, P; Danielson, UH; Karlén, A; Sandström, A Vinylated linear P2 pyrimidinyloxyphenylglycine based inhibitors of the HCV NS3/4A protease and corresponding macrocycles. Bioorg Med Chem 22: 6595 -615 (2015) Arellano, Y; Bratoeff, E; Heuze, Y; Bravo, M; Soriano, J; Cabeza, M Activity of steroid 4 and derivatives 4a-4f as inhibitors of the enzyme 5α-reductase 1. Bioorg Med Chem 26: 4058 -4064 (2018) Arasappan, A; Njoroge, FG; Chan, TY; Bennett, F; Bogen, SL; Chen, K; Gu, H; Hong, L; Jao, E; Liu, YT; Lovey, RG; Parekh, T; Pike, RE; Pinto, P; Santhanam, B; Venkatraman, S; Vaccaro, H; Wang, H; Yang, X; Zhu, Z; Mckittrick, B; Saksena, AK; Girijavallabhan, V; Pichardo, J; Butkiewicz, N; Ingram, R; Malcolm, B; Prongay, A; Yao, N; Marten, B; Madison, V; Kemp, S; Levy, O; Lim-Wilby, M; Tamura, S; Ganguly, AK Hepatitis C virus NS3-4A serine protease inhibitors: SAR of P'2 moiety with improved potency. Bioorg Med Chem Lett 15: 4180 -4 (2005) Thomas, JB; Mascarella, SW; Burgess, JP; Xu, H; McCullough, KB; Rothman, RB; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI N-substituted octahydro-4a-(3-hydroxyphenyl)-10a-methyl-benzo[g]isoquinolines are opioid receptor pure antagonists. Bioorg Med Chem Lett 8: 3149 -52 (1999) Ernst, JT; Thompson, PA; Nilewski, C; Sprengeler, PA; Sperry, S; Packard, G; Michels, T; Xiang, A; Tran, C; Wegerski, CJ; Eam, B; Young, NP; Fish, S; Chen, J; Howard, H; Staunton, J; Molter, J; Clarine, J; Nevarez, A; Chiang, GG; Appleman, JR; Webster, KR; Reich, SH Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase. J Med Chem 63: 5879 -5955 (2020) Judd, DB; Brown, DS; Lloyd, JE; McElroy, AB; Scopes, DI; Birch, PJ; Hayes, AG; Sheehan, MJ Synthesis, antinociceptive activity, and opioid receptor profiles of substituted trans-3-(decahydro- and octahydro-4a-isoquinolinyl)phenols. J Med Chem 35: 48 -56 (1992) Venkatraman, S; Njoroge, FG; Girijavallabhan, VM; Madison, VS; Yao, NH; Prongay, AJ; Butkiewicz, N; Pichardo, J Design and synthesis of depeptidized macrocyclic inhibitors of hepatitis C NS3-4A protease using structure-based drug design. J Med Chem 48: 5088 -91 (2005) Slater, MJ; Andrews, DM; Baker, G; Bethell, SS; Carey, S; Chaignot, H; Clarke, B; Coomber, B; Ellis, M; Good, A; Gray, N; Hardy, G; Jones, P; Mills, G; Robinson, E Design and synthesis of ethyl pyrrolidine-5,5-trans-lactams as inhibitors of hepatitis C virus NS3/4A protease. Bioorg Med Chem Lett 12: 3359 -62 (2002) Iwatani-Yoshihara, M; Ito, M; Ishibashi, Y; Oki, H; Tanaka, T; Morishita, D; Ito, T; Kimura, H; Imaeda, Y; Aparicio, S; Nakanishi, A; Kawamoto, T Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay. ACS Chem Biol 12: 1760 -1768 (2017) Welch, WM; Harbert, CA; Sarges, R; Weissman, A; Koe, BK Neuroleptics from the 4a,9b-trans-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole series. 3. Carboxamidoalkyl derivatives. J Med Chem 29: 2108 -11 (1986) Bogen, SL; Ruan, S; Liu, R; Agrawal, S; Pichardo, J; Prongay, A; Baroudy, B; Saksena, AK; Girijavallabhan, V; Njoroge, FG Depeptidization efforts on P3-P2' alpha-ketoamide inhibitors of HCV NS3-4A serine protease: effect on HCV replicon activity. Bioorg Med Chem Lett 16: 1621 -7 (2006) Ali, A; Aydin, C; Gildemeister, R; Romano, KP; Cao, H; Ozen, A; Soumana, D; Newton, A; Petropoulos, CJ; Huang, W; Schiffer, CA Evaluating the Role of Macrocycles in the Susceptibility of Hepatitis C Virus NS3/4A Protease Inhibitors to Drug Resistance. ACS Chem Biol 8: 1469 -78 (2013) Bogen, S; Saksena, AK; Arasappan, A; Gu, H; Njoroge, FG; Girijavallabhan, V; Pichardo, J; Butkiewicz, N; Prongay, A; Madison, V Hepatitis C virus NS3-4A serine protease inhibitors: use of a P2-P1 cyclopropyl alanine combination for improved potency. Bioorg Med Chem Lett 15: 4515 -9 (2005) Colarusso, S; Koch, U; Gerlach, B; Steinkühler, C; De Francesco, R; Altamura, S; Matassa, VG; Narjes, F Phenethyl amides as novel noncovalent inhibitors of hepatitis C virus NS3/4A protease: discovery, initial SAR, and molecular modeling. J Med Chem 46: 345 -8 (2003) Parsy, C; Alexandre, FR; Brandt, G; Caillet, C; Cappelle, S; Chaves, D; Convard, T; Derock, M; Gloux, D; Griffon, Y; Lallos, L; Leroy, F; Liuzzi, M; Loi, AG; Moulat, L; Musiu, C; Rahali, H; Roques, V; Seifer, M; Standring, D; Surleraux, D Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease. Bioorg Med Chem Lett 24: 4444 -9 (2014) Jiang, Y; Andrews, SW; Condroski, KR; Buckman, B; Serebryany, V; Wenglowsky, S; Kennedy, AL; Madduru, MR; Wang, B; Lyon, M; Doherty, GA; Woodard, BT; Lemieux, C; Geck Do, M; Zhang, H; Ballard, J; Vigers, G; Brandhuber, BJ; Stengel, P; Josey, JA; Beigelman, L; Blatt, L; Seiwert, SD Discovery of danoprevir (ITMN-191/R7227), a highly selective and potent inhibitor of hepatitis C virus (HCV) NS3/4A protease. J Med Chem 57: 1753 -69 (2014) Iyer, MR; Lee, YS; Deschamps, JR; Rothman, RB; Dersch, CM; Jacobson, AE; Rice, KC Probes for narcotic receptor mediated phenomena. 40. N-substituted cis-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ols. Bioorg Med Chem 18: 91 -9 (2010) Sun, LQ; Mull, E; D'Andrea, S; Zheng, B; Hiebert, S; Gillis, E; Bowsher, M; Kandhasamy, S; Baratam, VR; Puttaswamy, S; Pulicharla, N; Vishwakrishnan, S; Reddy, S; Trivedi, R; Sinha, S; Sivaprasad, S; Rao, A; Desai, S; Ghosh, K; Anumula, R; Kumar, A; Rajamani, R; Wang, YK; Fang, H; Mathur, A; Rampulla, R; Zvyaga, TA; Mosure, K; Jenkins, S; Falk, P; Tagore, DM; Chen, C; Rendunchintala, K; Loy, J; Meanwell, NA; McPhee, F; Scola, PM Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection. J Med Chem 63: 14740 -14760 (2020) Nageswara Rao, D; Zephyr, J; Henes, M; Chan, ET; Matthew, AN; Hedger, AK; Conway, HL; Saeed, M; Newton, A; Petropoulos, CJ; Huang, W; Kurt Yilmaz, N; Schiffer, CA; Ali, A Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants. J Med Chem 64: 11972 -11989 (2021) Iyer, MR; Rothman, RB; Dersch, CM; Jacobson, AE; Rice, KC Probes for narcotic receptor mediated phenomena 49. N-substituted rac-cis-4a-arylalkyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols. Eur J Med Chem 92: 531 -9 (2015) Hepatitis C: The Story of a Long Journey through First, Second, and Third Generation NS3/4A Peptidomimetic Inhibitors. What Did We Learn? Baker, JG; Adams, LA; Salchow, K; Mistry, SN; Middleton, RJ; Hill, SJ; Kellam, B Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for humanß-adrenoceptors. J Med Chem 54: 6874 -87 (2011) Welch, WM; Ewing, FE; Harbert, CA; Weissman, A; Koe, BK 4a,9b-trans-8-Fluoro-5-(4-fluorophenyl)-2-[4-(4-fluorophenyl)-4-hydroxybutyl]-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole hydrochloride, a new potent neuroleptic. J Med Chem 23: 949 -52 (1980) Arasappan, A; Njoroge, FG; Parekh, TN; Yang, X; Pichardo, J; Butkiewicz, N; Prongay, A; Yao, N; Girijavallabhan, V Novel 2-oxoimidazolidine-4-carboxylic acid derivatives as hepatitis C virus NS3-4A serine protease inhibitors: synthesis, activity, and X-ray crystal structure of an enzyme inhibitor complex. Bioorg Med Chem Lett 14: 5751 -5 (2004)
BDBM158431 US9029399, 4A US9339501, 4A
BDBM364404 US11555013, Compound 4a US9862679, Compound 4a US10913711, Compound 4a
BDBM312065 US9949951, 4a US9603836, Compound 4a
US10745364, Example 4A BDBM352492 US9809561, 4A
US9035074, 4A BDBM159751 US10966980, Example 4A
BDBM100358 US12251379, Compound 4a US10383835, Compound 4a US11123311, Compound 4a US8501783, 1154
US10730826, Compound 4a US11325884, Compound 4a BDBM453293
US10919858, Example 4A BDBM377568 US10266493, Example 4A
US11007200, Example 4a US11426411, Example 4a BDBM497388
US11179370, Example 4a US9987253, Example 4a US10617673, Example 4a (2S,4'R) BDBM286107 US9517228, Example 4a (2S,4′R)
US10806724, Example 2-4A US10335399, Example 2-4A BDBM403458
BDBM132100 USRE45173, 4A
BDBM174467 US9102670, 4a
BDBM179960 US9133148, 4a
BDBM185754 US9162991, 4a
BDBM199099 US9221839, 4a
BDBM200668 US9233086, 4A
BDBM202867 US9242970, 4a
BDBM205981 US9255091, 4a
BDBM208781 US9266878, 4a
BDBM242923 US9422255, 4a
BDBM244050 US9428476, 4a
BDBM247280 US9447085, 4a
BDBM256353 US9487490, 4A
BDBM29279 triazole, 4a
BDBM97555 US8470825, 4a
Carbacylamidophosphate, 4a BDBM91729
Isocoumarin, 4a BDBM81594
URB602, 4a BDBM81324
US8829029, 4A BDBM180701
US8937058, 4A BDBM142636
US9346794, 4A BDBM232368
US9403801, 4A BDBM239948
US9428492, 4a BDBM244122
US9493474, 4A BDBM254072
US11117902, Example 4B US11634426, Example 4A BDBM443437 US10654866, Example 4A
BDBM150253 US8980932, 4a (DH296)
BDBM180287 US9133168, Example 4a
BDBM243049 PTP inhibitor, 4a
BDBM291134 US9580396, Example 4a
BDBM304237 US10143695, Compound 4A
BDBM359499 US10221142, Example 4A
BDBM363471 US9850245, Example 4A
BDBM404265 US10017502, Example 4a
BDBM404636 US10344000, Example 4A
BDBM514195 US11053196, Compound 4A
BDBM541775 US11267824, Example 4a
BDBM550870 US11312709, Example 4a
BDBM562462 US11401295, Compound 4A
BDBM577201 US11472811, Example 4A
BDBM590007 US11560368, Example 4a
BDBM605741 US11680056, Example 4A
BDBM618504 US20230287003, Example 4a
BDBM662969 US20240109879, Compound 4A
BDBM665898 US20240116922, Comparator 4A
BDBM686298 US20240246932, Example 4A
BDBM695252 US12083101, Example 4a
BDBM698121 US20240317721, Example 4a
BDBM700437 US20240336629, Compound 4A
BDBM704117 US12138263, Compound 4A
BDBM84615 Mannostatin analogue, 4a
BDBM85758 Thienopyrrolizine derivative, 4a
BDBM86332 Phosphodiester analog, 4a
BDBM86772 Phthalonitrile analogue, 4a
BDBM93260 CypA Inhibitor, 4a
US10550102, Example 4a BDBM430861
US10766893, Example 4a BDBM462235
US11192850, Entry 4a BDBM528529
US11560385, Compound 4A BDBM590194
US11718589, Compound 4a BDBM611581
US11731944, Example 4a BDBM613570
US11739090, Compound 4A BDBM613979
US12161642, Example 4a BDBM707259
US20230331683, Compound 4a BDBM627444
US20240166635, Example 4a BDBM676213
US20240166642, Example 4a BDBM676510
US20240239813, Compound 4a BDBM685634
US20240254109, Example 4A BDBM689186
US20250002435, Compound 4a BDBM710418
US20250230129, Compound 4A BDBM757780
US8691829, 4a CHEMBL2216871 BDBM50403092
US9469608, 23-4a BDBM252993
iodinated benzimidazole, 4a BDBM34041
piperazine amide, 4a BDBM32453
(S)-2-(2,6-dimethylbenzamido)-4-((R)- BDBM448757 US10696672, Compound 4a US11634418, Compound 4a
BDBM127956 US8796310, 4A US8796310, 4
BDBM141918 US8921559, 4b US8921559, 4a
BDBM210935 4-(phenyl)-bezenesulfonamide (4a)
BDBM289502 US10093663, Example 27-4a
BDBM30466 benzothiazine-containing analog, 4a
BDBM314090 US9610322, 4a (cis olefin)
BDBM34106 glucopyranosylidene-spiro-isoxazoline, 4a
BDBM486048 US10947210, Compound 05-4A
BDBM486161 US10947210, Compound 10-4A
BDBM50572108 US20240043448, Example 4a CHEMBL4869082
BDBM92806 US9249124, 22 Bisanilinopyrimidine, 4a
BODIPY-labeled probe, 4a BDBM81374
LecB Inhibitor Amides 4a BDBM103990
Tetrahydroisoquinoline hydantoin derivative, 4a BDBM85665
US10968163, Compound 4a CHEMBL4276759 BDBM50468442
US12030867, Compound 4a CHEMBL4763549 BDBM50557187
US12083101, Example 4a-1 BDBM695256
US20250154153, Compound 1218-4A BDBM740624
US9365589, 4a US9365589, 4b BDBM236601
US9682968, Example-27-4a (+) BDBM160485
cid_2826978 3-(1,2,3,4-tetrahydrocarbazol-4a-yl)propanenitrile BDBM42802 3-(1,2,3,4-tetrahydro-4aH-carbazol-4a-yl)propanenitrile MLS000052957 3-(1,2,3,4-tetrahydrocarbazol-4a-yl)propionitrile SMR000068914
US11731954, Example 4A US10059687, Example 4A US11001568, Example 4A 3-[({(1S)-6-[4-(cyclopropylmethoxy)-2-methylphenyl]-1,2,3,4-tetrahydroisoquinolyl}methyl)amino]pyridine-4-carboxylic acid BDBM270500
US10501436, Compound 4a BDBM280339 US11053216, Compound 4a US10030004, Compound 4a US11702401, Compound 4a (S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-yl)pyridin-4-ylamino)-N-(2-hydroxypropyl)pyrimidine-5-carboxamide
2-Allyl-1,4-dimethoxybenzene (4a) BDBM234357
5-vinyl-3-pyridinecarbonitrile, 4a BDBM35116
BDBM192003 Isoquinolin-1(2H)-ones, 4a
BDBM36666 Dansyl derivatives 4A, (S) isomer
BDBM495085 US10995084, Ex. No. 4A-1
BDBM495090 US10995084, Ex. No. 4A-5
BDBM495091 US10995084, Ex. No. 4A-6
BDBM495092 US10995084, Ex. No. 4A-7
Benzylquinoline, 8a BMC171663 Compound 4a BDBM35087
Quinolone-based HDAC inhibitor 4a BDBM65458
US10017502, Example 4b US9394291, 4a BDBM238159
US10995084, Ex. No. 4A-2 BDBM495087
US10995084, Ex. No. 4A-3 BDBM495088
US10995084, Ex. No. 4A-4 BDBM495089
US11459295, Compound (R) 4a BDBM50533573 CHEMBL4437291
1,3-thiazolidin-5-ylidene derivative, 4a BDBM31937
BDBM218849 US9303033, G1, Table 4A, Compound 1
BDBM218851 US9303033, I1, Table 4A, Compound 3
BDBM218858 US9303033, P1, Table 4A, Compound 10
BDBM336830 US9745289, Compound 4B US9745289, Compound 4A
CHEMBL72166 BDBM50051363 1,2,3,4-Tetrahydro-carbazol-4a-ol
US11702409, Example 4b US11702409, Example 4a BDBM608830
US9303033, H1, Table 4A, Compound 2 BDBM218850
US9303033, N1, Table 4A, Compound 8 BDBM218856
US9303033, O1, Table 4A, Compound 9 BDBM218857
US9346794, 4A US9346794, 4B US9346794, 4 BDBM232300
US9428492, 4 US9428492, 4a BDBM244121 US9428492, 4b
US9845308, Example 5a BDBM362868 US9845308, Example 4a
BDBM93910 7-bromo-4a,9a-dihydroxanthen-9-one cid_44601500 MLS000518033 SMR000327218 7-bromanyl-4a,9a-dihydroxanthen-9-one
(1S,3S,4S,4a,9aS)-1,3,4,8-tetrahydroxy-4a,6-dimethyl-1,2,3,4,4a,9a-hexahydro-9H-xanthen-9-one BDBM50204914 CHEMBL373944
SMR000014065 MLS000074557 1-p-anisyl-2,3,4,5,6,7,8,8a-octahydro-1H-isoquinolin-4a-ol cid_655005 BDBM41759 1-[(4-methoxyphenyl)methyl]-2,3,4,5,6,7,8,8a-octahydro-1H-isoquinolin-4a-ol 1-(4-Methoxy-benzyl)-octahydro-isoquinolin-4a-ol
BDBM123656 US10562890, Compound 4a US8748618, AI-4-52
BDBM476204 US10865384, Example 4a US10865384, Compound IM-16
CHEMBL2313284 BDBM50425477 (E)-8-(4-Chlorostyryl)caffeine (4a)
Enantiomers of Example 4 US9657015, Example 4A BDBM310009
US10202373, Example 4A BDBM346215 US10202373, Compound I-29
indole-based 6-membered lactam, (R)-4a BDBM30284
indole-based 6-membered lactam, (S)-4a BDBM30285
US11673864, Compound 30 US9051270, 30 BDBM161245 US10087143, Compound 30 US9758483, Compound 30 US9163042, 4a US10738009, Compound 52 US10787472, Compound 4a
cis-4-(3,4-Dimethoxyphenyl)-4a,5,8,8a-tetrahydro-2Hphthalazin-1-one (cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one BDBM50304391 CHEMBL440878 cis-(+/-)-4-(3,4-Dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
7-(Benzyloxy)-3,4-dihydronaphthalen-1(2H)-one (4a) BDBM166630
BDBM209028 US9243038, 4a (cis olefin) US9243038, 4b (trans olefin)
BDBM223127 2-((5-phenylfuran-2-yl)methylene)hydrazinecarboxamide (4a)
BDBM232978 (E)-3-(4-(benzyloxy)phenyl)-N-hydroxyacrylamide (4a)
BDBM486150 US10947210, Compound 10-3A US10947210, Compound 10-4A
BDBM724208 US20250066338, Ref Comp B WO2018109607, Ex 4A-01
hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 4a BDBM30450
(1H-Benzoimidazol-5-yl)-[(4a-S,10b-R)-2,3, 4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl]-methanone US9663470, 2 BDBM327780
BDBM235011 4-(1-(2-bromo-6-(trifluoromethyl)benzyl)-4-fluoro-1H-indazol-3-yl)-5-fluoro-2-hydroxybenzoic acid (4A) US9556168, 4A
4-oxidanidyl-3-(4-phenoxyphenyl)-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxide 4-oxido-3-(4-phenoxyphenyl)-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxide 2-(4-phenoxyphenyl)-4a,5,6,7,8,8a-hexahydroquinoxaline 1,4-dioxide BDBM40469 cid_2966106 MLS000051260 SMR000079265
US10196354, Example 4A BDBM332440 4-(1-(2-chloro-6-(trifluoromethyl) benzoyl)-6-(3-hydroxyazetidin-1-yl)-1H-indazol-3-yl)benzoic acid (4A)
3-(2-benzofuranyl)-4-oxido-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxide 3-(benzofuran-2-yl)-4-oxido-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxide cid_2966212 BDBM39492 MLS000065441 2-(1-benzofuran-2-yl)-4a,5,6,7,8,8a-hexahydroquinoxaline 1,4-dioxide SMR000079285 3-(1-benzofuran-2-yl)-4-oxidanidyl-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxide 3-(1-benzofuran-2-yl)-4-oxido-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxide
1,2,3,4,5,6,11,11b-Octahydro-4a,10,11-triaza-benzo[a]fluorene BDBM50018738 CHEMBL345621
1-(1,3,4,8b-Tetrahydro-2H-biphenylen-4a-yl)-piperidine CHEMBL142600 BDBM50062780
2,4-di-tert-butyl-6-(1-phenylethyl)phenol, 4a BDBM34128
3-(2-Cyclopropylmethyl-octahydro-isoquinolin-4a-yl)-phenol BDBM50000087 CHEMBL153538
3-(2-Ethyl-octahydro-isoquinolin-4a-yl)-phenol CHEMBL150667 BDBM50018733
3-(2-Phenethyl-octahydro-isoquinolin-4a-yl)-phenol CHEMBL359363 BDBM50018730
6,7-Dimethyl-4a,5,6,7,8,8a-hexahydro-quinazoline-2,4-diamine CHEMBL82825 BDBM50130954
7H-4a,5,7,12-Tetraaza-indeno[1,2-a]fluorene BDBM50083886 CHEMBL367639
BDBM23985 3,4-dihydro-1H-2-benzopyran-3-one isochromanone, 4a
BDBM50018728 3-(2-Methyl-octahydro-isoquinolin-4a-yl)-phenol CHEMBL155216
BDBM50018729 CHEMBL153661 3-(2-Propyl-octahydro-isoquinolin-4a-yl)-phenol
BDBM605738 US11680056, Example 4 US11680056, Example 4B US11680056, Example 4A
CHEMBL82985 7-Methyl-4a,5,6,7,8,8a-hexahydro-quinazoline-2,4-diamine BDBM50130958
US11117902, Example 4A BDBM443444 US10654866, Example 4B US11634426, Example 4B
jm5b01461, Compound 177 acs.jmedchem.1c00409_ST.31 BDBM429360 cmdc.202100576, 4a
10-(3-pyridinylmethyl)-2,3,4,5,6,7,8,8a,9,9a-decahydro-1H-acridine-4a,10a-dicarbonitrile cid_657440 SMR000038251 10-(3-pyridylmethyl)-2,3,4,5,6,7,8,8a,9,9a-decahydro-1H-acridine-4a,10a-dicarbonitrile BDBM87385 MLS000079445 10-(pyridin-3-ylmethyl)-2,3,4,5,6,7,8,8a,9,9a-decahydro-1H-acridine-4a,10a-dicarbonitrile
(4aS,10aR)-4a-benzyl-7-hydroxy-3,4,4a,9,10,10a-hexahydrophenanthren-2(1H)-one CHEMBL310180 4a-Benzyl-7-hydroxy-3,4,4a,9,10,10a-hexahydro-1H-phenanthren-2-one BDBM50113777
4a-methyl-4,5,6,7,8,8a-hexahydro-1H-benzo[d]oxathiazine 2,2-dioxide SMR000639274 4a-methyl-4,5,6,7,8,8a-hexahydro-1H-benzo[d][1,2,3]oxathiazine 2,2-dioxide BDBM66803 cid_11694131 MLS001075215
BDBM394484 Enantiomer 1 and Enantiomer 2 of (trans-4a,8a)-2-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)decahydroisoquinolin-4a-ol US10308614, Example 84
Enantiomer 1 and Enantiomer 2 of (trans-4a,8a)-2-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)decahydroisoquinolin-4a-ol BDBM394485 US10308614, Example 85
US11440884, Example 4a [4-(propan-2-yloxy)phenyl]methyl N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-N-[(4-fluorophenyl)methyl]carbamate (4a) BDBM570525
2-amino-4-(3-pyridyl)-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile cid_645772 2-azanyl-4-pyridin-3-yl-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile BDBM50752 2-amino-4-pyridin-3-yl-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile MLS000031410 SMR000009389 2-amino-4-(3-pyridinyl)-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile
5-keto-10a-methyl-10-oxido-1,2,3,4,6,7,8,9-octahydrophenazin-5-ium-4a-ol cid_657918 10a-methyl-10-oxido-5-oxo-1,2,3,4,6,7,8,9-octahydrophenazin-5-ium-4a-ol BDBM48323 MLS000079684 SMR000038759 10a-methyl-10-oxidanidyl-5-oxidanylidene-1,2,3,4,6,7,8,9-octahydrophenazin-5-ium-4a-ol
6,8-dinitro-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one (4a) BDBM222148
BDBM153276 (Z)-2-(2,5-Dimethoxybenzylidene)-4-methoxybenzofuran-3(2H)-one (4a)
BDBM621799 US11802122, Example 4A US20230312522, Compound 6 US20230312522, Compound 7 BDBM621741
4a,12a-Dihydroxy-9-(4-methoxy-phenyl)-4,4,6a,12b-tetramethyl-4a,6,6a,12,12a,12b-hexahydro-4H,5H-7,10-dioxa-benzo[a]anthracene-1,11-dione CHEMBL278342 BDBM50089621
CHEMBL283509 BDBM50089619 9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-4a,6,6a,12,12a,12b-hexahydro-4H,5H-7,10-dioxa-benzo[a]anthracene-1,11-dione
1-(4-Fluorophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-phenylurea (4a) BDBM237212
1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1 H-indole, 4a BDBM82352
2-(4-(4-Nitrophenyl)thiazol-2-ylimino)thiazolidin-4-one (4a) BDBM175280
4-anilinoquinazoline 4a BDBM5448 4-{[4-(benzyloxy)phenyl]amino}quinazolin-6-ol
7,7-Dimethyl-hexadecahydro-9,22-dioxa-4a-aza-benzocyclohenicosene-5,6,10,23-tetraone BDBM50283388 CHEMBL109750
BDBM123814 4,5-dibromo-N'-(2-hydroxybenzylidene)-1H-pyrrole-2-carbohydrazide (4a)
BDBM23280 6-chloro-N-hydroxy-1H-indene-2-carboxamide hydroxamate derivative, 4a
BDBM235660 3-(5-Phenyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one (4a)
BDBM50018736 1,3,4,5,6,11b-Hexahydro-2H-11-oxa-4a-aza-benzo[a]fluorene CHEMBL158371
BDBM50018739 1,3,4,5,6,11b-Hexahydro-2H-11-thia-4a-aza-benzo[a]fluorene CHEMBL346492
BDBM50083897 CHEMBL366789 1-Chloro-7H-4a,5,7,12-tetraaza-indeno[1,2-a]fluorene
CHEMBL320252 7,7-Dimethyl-tetradecahydro-9,20-dioxa-4a-aza-benzocyclononadecene-5,6,10,21-tetraone BDBM50283391
CHEMBL324019 BDBM50283386 7,7-Dimethyl-icosahydro-9,26-dioxa-4a-aza-benzocyclopentacosene-5,6,10,27-tetraone
CHEMBL419746 7,7-Dimethyl-octahydro-9,14-dioxa-4a-aza-benzocyclotridecene-5,6,10,15-tetraone BDBM50283392
Enone, 4a (2E)-4-(4-hexylphenyl)-4-oxobut-2-enoic acid BDBM18826
(2R,4aS,10aR)-4a-benzyl-2-(chloroethynyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol 4a-Benzyl-2-chloroethynyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-2,7-diol(CP-394531) BDBM50113783 CP-394531 CHEMBL77779
BDBM50089616 territrem B CHEMBL24686 4a,12a-Dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-trimethoxy-phenyl)-4a,6,6a,12,12a,12b-hexahydro-4H,5H-7,10-dioxa-benzo[a]anthracene-1,11-dione
CHEMBL483849 {[(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid BDBM22579 Aminoimidazole-4-carboxamide ribonucleotide AICAR ZMP
2-amino-6-phenyl-4-(3-pyridyl)-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile;ethanol 2-Amino-6-phenyl-4-pyridin-3-yl-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile BDBM63025 2-amino-6-phenyl-4-pyridin-3-yl-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile;ethanol cid_9551775 MLS000552612 2-amino-6-phenyl-4-(3-pyridinyl)-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile;ethanol 2-azanyl-6-phenyl-4-pyridin-3-yl-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile;ethanol SMR000146127
1',4a'-dimethylspiro[tetrahydrofuran-2,7'-perhydroindeno[5,4-f]quinoline]-2'-one CHEMBL3349097 BDBM50025412
BDBM218852 US9303033, Z38, Table 43A, Compound 3 US9303033, J1, Table 4A, Compound 4
BDBM218853 US9303033, K1, Table 4A, Compound 5 US9303033, B39, Table 43A, Compound 5
BDBM218854 US9303033, L1, Table 4A, Compound 6 US9303033, D39, Table 43A, Compound 7
BDBM222079 6-(4-nitrophenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile (4a)
BDBM50025433 CHEMBL3349290 4a',6a'-dimethylspiro[tetrahydrofuran-2,7'-perhydroindeno[5,4-f]quinoline]-2'-one
BDBM50116677 CHEMBL74679 (4aR,8aR)-4-Methyl-4a,5,6,7,8,8a-hexahydro-1H-quinolin-(2E)-ylideneamine
BDBM668141 US20240124450, Example 4D US20240124450, Example 4B US20240124450, Example 4C US20240124450, Example 4A
BDBM8965 methylbis[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]amine Tacrine Dimer 4a CHEMBL338755
CHEMBL126891 BDBM50031068 4a,4b-Dihydro-5,6-diaza-indeno[2,1-a]phenanthren-11-one
Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine- 5-carboxylate (4a) BDBM112642
US11685719, Example 21A US11685719, Example 21B US11685719, Example 4A US11685719, Example 4B BDBM606213
US9303033, A39, Table 43A, Compound 4 BDBM218859 US9303033, Q1, Table 4A, Compound 11
US9303033, F39, Table 43A, Compound 9 US9303033, M1, Table 4A, Compound 7 BDBM218855
US9303033, S1, Table 4A, Compound 13 US9303033, E39, Table 43A, Compound 8 BDBM218861
BDBM50025437 CHEMBL3349135 4a',6a'-dimethylspiro[tetrahydrofuran-2,7'-(2',4a',4b',5',6',6a',7',8',9',9a',9b',10',11',11a'-tetradecahydro-1'H-indeno[5,4-f]quinoline)]-2'-one
2-azanyl-6-tert-butyl-4-(4-ethylphenyl)-4a,5,6,7-tetrahydro-4H-naphthalene-1,1,3-tricarbonitrile BDBM57050 MLS000548569 2-amino-6-tert-butyl-4-(4-ethylphenyl)-4a,5,6,7-tetrahydro-4H-naphthalene-1,1,3-tricarbonitrile 2-amino-6-tert-butyl-4-(4-ethylphenyl)-4a,5,6,7-tetrahydro-1,1,3(4H)-naphthalenetricarbonitrile cid_4466047 SMR000115124
cid_653599 2-azanyl-6-methyl-4-thiophen-2-yl-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile BDBM50766 2-amino-6-methyl-4-thiophen-2-yl-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile MLS000034864 2-amino-6-methyl-4-(2-thienyl)-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile SMR000014521
(4R,4aR,6aR,12aS,12bS)-4a,12a-dihydroxy-4-(hydroxymethyl)-4,6a,12b-trimethyl-9-(3,4,5-trimethoxyphenyl)-4a,5,6,6a,12,12a-hexahydrobenzo[f]pyrano[4,3-b]chromene-1,11(4H,12bH)-dione BDBM50292395 CHEMBL465764
(6R,9S)- or (6S,9R)- 4-(1-methyl-1H- pyrazol-4-yl)-6,7,8,9- tetrahydro-5H-6,9- epoxycyclo- hepta[b]pyridine-2- carboxamide BDBM403442 US10806724, Example 1-4A US10335399, Example 1-4A
CHEMBL3349087 BDBM50025370 1',4a',6a'-trimethylspiro[tetrahydrofuran-2,7'-(2',4a',4b',5',6',6a',7',8',9',9a',9b',10',11',11a'-tetradecahydro-1'H-indeno[5,4-f]quinoline)]-2'-one
cis-(+/-)-2-(5-Bromo-pentyl)-4-(3,4-dimethoxy-phenyl-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one BDBM50304392 (cis)-2-(5-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one CHEMBL463431
cis-(-)-4-(3,4-Dimethoxyphenyl)-2-[4-(morpholinomethyl)benzyl]-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one CHEMBL593877 BDBM50304417 CHEMBL593656 cis-(+/-)-4-(3,4-Dimethoxyphenyl)-2-[4-(morpholinomethyl)benzyl]-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
(R)-4a-Benzyl-7-hydroxy-4,4a,9,10-tetrahydro-3H-phenanthren-2-one BDBM50113781 CHEMBL78646
(S)-4a-Benzyl-7-hydroxy-4,4a,9,10-tetrahydro-3H-phenanthren-2-one CHEMBL310370 BDBM50113779
(S)-4a-Benzyl-7-methoxy-4,4a,9,10-tetrahydro-3H-phenanthren-2-one CHEMBL82307 BDBM50113778
(S)-7-Chloro-4a-methyl-3,4,4a,9-tetrahydro-phenanthrene-2-carboxylic acid BDBM50057501 CHEMBL25081
1',4a',6a'-trimethylspiro[tetrahydrofuran-2,7'-perhydroindeno[5,4-f]quinoline]-2'-one BDBM50025330 CHEMBL3349147
7-Acetyl-4a,6a-dimethyl-hexadecahydro-indeno[5,4-f]quinolin-2-one BDBM50025347 CHEMBL3349071
7-Hydroxy-4-oxo-4a,8a-dihydro-4H-chromene-2-carboxylic acid BDBM50025972 CHEMBL422920
BDBM170124 4-(5-(2-Hydroxyphenyl)-3-phenyl-4, 5-dihydro pyrazole) benzene sulfonamide (4a)
BDBM22713 N-benzyl-5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxamide Dihydroxypyrimidine, 4a
BDBM234418 (S)-Ethyl 2-(2-(2-(tert-butoxycarbonylamino)propanamido)thiazol-4-yl)acetate (4a)
BDBM394427 US10308614, Example 28 US10308614, Example 84 (trans-4a,8a)-2-(3-amino-6-
BDBM50025432 7-Hydroxy-4a,6a-dimethyl-hexadecahydro-indeno[5,4-f]quinolin-2-one CHEMBL3349125
BDBM50104895 CHEMBL111984 7-Chloro-4-methyl-3-phenyl-4a,5,6,7,8,8a-hexahydro-chromen-2-one
BDBM50113776 (R)-4a-Benzyl-7-methoxy-4,4a,9,10-tetrahydro-3H-phenanthren-2-one CHEMBL78807
BDBM50157832 CHEMBL361350 3-Hydroxy-4a,7a-dihydro-1H-thieno[2,3-d]pyrimidine-2,4-dione
BDBM50276435 (4aS,10aR)-4a-Hydroxymethyl-2-prop-1-ynyl-1,2,3,4,4a,9,10,10aoctahydrophenanthrene-2,7-diol CHEMBL456214
BDBM50276474 (2R,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol CHEMBL462100
CHEMBL137800 7-Methoxy-9-oxo-4a,9,9a,10-tetrahydro-acridine-2-diazonium; chloride BDBM50107129
CHEMBL337439 BDBM50053920 4-Hydroxy-3-(1-phenyl-propyl)-4a,5,6,7,8,8a-hexahydro-chromen-2-one
N-(1,1-dioxothiolan-3-yl)-2-[(4-methylphenoxy)methyl]thiazole-4-carboxamide (4a) BDBM231675
N-(diphenylmethyl)-3-hydroxy-4-oxo-4H-pyran-2-carboxamide hydroxypyrone amide, 4a BDBM27852
diphenylalkylamine (DPA), 4a 2,2-diphenylethylamine EN300-13160 2,2-diphenylethanamine CHEMBL10780 BDBM35929 2,2-Diphenyl-ethylamine
(2R,4aS,10aR)-4a-benzyl-2-(prop-1-ynyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol BDBM50113780 4a-Benzyl-2-prop-1-ynyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-2,7-diol(CP-409069) CHEMBL78625 CP-409069
(S)- or (R)-2- ((difluoro- methoxy)methyl)- 5-(1- (difluoromethyl)- 1H-pyrazol-4-yl)- 3,4-dihydro-2H- pyrano[2,3- b]pyridine-7- carboxamide US10335399, Example 3-4A US10806724, Example 3-4A BDBM403476
2-[1-(2,5-dimethoxyphenyl)-4a-oxidanyl-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-N-(4-methoxyphenyl)ethanamide 2-[1-(2,5-dimethoxyphenyl)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-N-(4-methoxyphenyl)acetamide BDBM89592 SMR000045322 cid_664325 MLS000041036
BDBM50142874 CHEMBL299327 N-{2-[(4aS,10aR)-6-methoxy-1,2,3,4,4a,10a-hexahydrophenanthren-4a-yl]ethyl}-1-(tert-butoxy)-N,N-dimethylcarbonyl{2-[(4aS,10aR)-6-methoxy-1,2,3,4,4a,10a-hexahydrophenanthren-4a-yl]ethyl}dimethylazanium
CHEMBL371311 BDBM50167794 1-(4-fluorophenyl)-4a-methylspiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] 1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)]
2-amino-6-tert-butyl-4-thiophen-2-yl-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile 2-azanyl-6-tert-butyl-4-thiophen-2-yl-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile MLS000552642 2-amino-6-tert-butyl-4-(2-thienyl)-4a,5,6,7-tetrahydro-4H-naphthalene-1,3,3-tricarbonitrile SMR000146157 BDBM57116 cid_3719172
2-azanyl-6-methyl-2'-oxidanylidene-1'-propyl-spiro[4a,5,6,7-tetrahydronaphthalene-4,3'-indole]-1,1,3-tricarbonitrile 2-amino-6-methyl-2'-oxo-1'-propylspiro[4a,5,6,7-tetrahydronaphthalene-4,3'-indole]-1,1,3-tricarbonitrile 2-amino-2'-keto-6-methyl-1'-propyl-spiro[4a,5,6,7-tetrahydronaphthalene-4,3'-indoline]-1,1,3-tricarbonitrile SMR000014579 BDBM67705 MLS000075472 cid_647536
(2R,4aS,10aR)-4a-Propenyl-2-prop-1-ynyl-1,2,3,4,4a,9,10,10aoctahydrophenanthrene-2,7-diol CHEMBL470152 BDBM50276171
1'-ethyl-4a',6a'-dimethylspiro[tetrahydrofuran-2,7'-perhydroindeno[5,4-f]quinoline]-2'-one BDBM50025400 CHEMBL3349293
1,3-dimethoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]benzene trans-Stilbene Derivative, 4a CHEMBL296411 BDBM23928
2-(2-Hydroxy-phenyl)-3-phenethyl-4a,5,6,7,8,8a-hexahydro-3H-quinazolin-4-one BDBM50166507 CHEMBL369998
2-(4a,8a-dihydronaphthalene-1-sulfonyl)-6-aminobenzonitrile BDBM1777 2-Amino-6-arylthiobenzonitrile deriv. 3ee
2-[(2S)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazole-4-carboxamide benzimidazole carboxamide, 4a BDBM27136
4aS,9aR-(-)-cis-4a-Ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro-[2,3-c]pyridin-6-ol CHEMBL567855 BDBM50300370
7-Hydroxymethyl-4a,7-dimethyl-4b,5,6,7,8,8a,9,10-octahydro-4aH-phenanthren-2-one CHEMBL348154 BDBM50020647
BDBM173574 N',N'',N'''-(pyridine-2,4,6-tricarbonyl)tribenzenesulfonohydrazide (4a)
BDBM198155 2-(5-Acetyl-6-methyl-4-phenyl-1,4-dihydropyrimidin-2-ylthio)-N-phenylacetamide (4a)
BDBM24251 (4S)-4-amino-4-{[4-(benzyloxy)phenyl]carbamoyl}butanoic acid Amino acid analog, 4a
BDBM50018612 CHEMBL30358 4-(4-Imidazol-1-yl-phenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one
BDBM50025348 1',4a',6a'-trimethylspiro[tetrahydrofuran-2,7'-perhydroindeno[5,4-f]quinoline]-2',5-dione CHEMBL3349114
BDBM50079905 CHEMBL112761 1,3,4,11a-Tetrahydro-2H-10-thia-4a-aza-dibenzo[a,d]cycloheptene-5,11-dione
BDBM50153516 5-(Hydroxy-phenyl-methyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-3H-naphthalen-2-one CHEMBL186893
BDBM50276126 CHEMBL511812 (2R,3S,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,3,7-triol
BDBM50276128 (2R,3R,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,3,7-triol CHEMBL470784
BDBM50300367 CHEMBL566749 4aR,9aS-(+)-cis-4a-Ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro-[2,3-c]pyridin-6-ol
BDBM50308917 CHEMBL592302 cis-(+/-)-4a-Ethyl-2-(4-fluorophenethyl)-1,2,3,4,4a,9ahexahydrobenzofuro[2,3-c]pyridin-8-ol
BDBM50308918 cis-(+/-)-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-hexahydrobenzofuro-[2,3-c]pyridin-8-ol CHEMBL599174
BDBM50308919 CHEMBL598977 cis-(+/-)-2-methyl-4a-phenethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ol
CHEMBL158325 BDBM50020642 4a,7-Dimethyl-7-propionyl-4b,5,6,7,8,8a,9,10-octahydro-4aH-phenanthren-2-one
CHEMBL158326 7-Acetyl-4a,7-dimethyl-4b,5,6,7,8,8a,9,10-octahydro-4aH-phenanthren-2-one BDBM50020639
CHEMBL177888 2-Amino-7-methyl-4a,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one BDBM50028121
CHEMBL511982 BDBM50276169 (2R,4aR,10aR)-4a-Methyl-2-prop-1-ynyl-1,2,3,4,4a,9,10,10aoctahydrophenanthrene-2,7-diol
CHEMBL589260 BDBM50308922 cis-(+/-)-2-(Cyclopropylmethyl)-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ol
CHEMBL599175 BDBM50308920 cis-(+/-)-4a-Ethyl-2-phenethyl-1,2,3,4,4a,9a-hexahydrobenzofuro-[2,3-c]pyridin-8-ol
Potassium; 4a,6a-dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylate BDBM50025419 CHEMBL3349128
sulfonyl urea 4a N-{[(benzenesulfonyl)carbamoyl]amino}-4-sulfamoylbenzamide BDBM12147 4-(N-phenylsulfonylaminocarbonyl-hydrazinocarbonyl)-benzenesulfonamide
3-Chloro-5-cyano-pyridine-2-carboxylic acid [3-((3R,4aS)-1-amino-3-methyl-4a-oxo-3,4,6,7,8,9-hexahydro-4a 6-thia-2,5,9a-triaza-benzocyclohepten-3-yl)-4-fluoro-phenyl]-amide BDBM312921 US9605006, 20
4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ol (4aS,9aR)-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol BDBM50017236 CHEMBL430441
5-But-2-ynyloxy-pyrazine-2-carboxylic acid [3-((3R,4aS)-1-amino-3-methyl-4a-oxo-3,4,6,7,8,9-hexahydro-4a 6-thia-2,5,9a-triaza-benzocyclohepten-3-yl)-4-fluoro-phenyl]-amide BDBM312923 US9605006, 22
5-Fluoro-3-methyl-pyridine-2-carboxylic acid [3-((3R,4aS)-1-amino-3-methyl-4a-oxo-3,4,6,7,8,9-hexahydro-4a 6-thia-2,5,9a-triaza-benzocyclohepten-3-yl)-4-fluoro-phenyl]-amide US9605006, 23 BDBM312925
BDBM312922 5-(2,2,2-Trifluoro-ethoxy)-pyridine-2-carboxylic acid [3-((3R,4aS)-1-amino-3-methyl-4a-oxo-3,4,6,7,8,9-hexahydro-4a 6-thia-2,5,9a-triaza-benzocyclohepten-3-yl)-4-fluoro-phenyl]-amide US9605006, 21
Isomer of4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-6b-[2-(2-oxo-tetrahydro-furan-3-ylsulfanyl)-acetyl]-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one BDBM50083757 Isomer of 4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-6b-[2-(2-oxo-tetrahydro-furan-3-ylsulfanyl)-acetyl]-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one CHEMBL302366
BDBM50017231 (4aS,9aR)-4a-Ethyl-2-phenethyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol CHEMBL72180 4aS,9aR-(-)-cis-4a-Ethyl-2-(2-phenylethyl)-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ol
BDBM50054959 CHEMBL357651 (4aS,4bR,5S,6aS,6bR,9aR)-4b-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-6b-methylsulfanyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one
CHEMBL158091 4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-6b-(2-oxo-tetrahydro-furan-3-ylsulfanyl)-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one BDBM50096154
(2R,3S,4aR,10aR)-4a-Ethyl-2-prop-1-ynyl-1,2,3,4,4a,9,10,10aoctahydrophenanthrene-2,3,7-triol BDBM50276471 CHEMBL457241
(2R,4aR,10aR)-4a-Ethyl-2-prop-1-ynyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol CHEMBL10560 BDBM50276170
3-((4aS,10aS)-2,10a-Dimethyl-1,3,4,5,10,10a-hexahydro-2H-benzo[g]isoquinolin-4a-yl)-phenol CHEMBL324681 BDBM50072453
3-((4aS,11aR)-2-Ethyl-1,2,3,4,5,6,11,11a-octahydro-pyrido[4,3-b]carbazol-4a-yl)-phenol CHEMBL107670 BDBM50061062
3-Hydroxy-5-methyl-4a,7a-dihydro-1H-thieno[2,3-d]pyrimidine-2,4-dione BDBM50157842 CHEMBL183792
4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one Efavirenz deriv. 4a BDBM2922
4-(3-phenylphenyl)thieno[2,3-c]pyridine-2-carboxylic acid thieno[2,3-c]pyridine, 4a BDBM28037
4-[(3-bromophenyl)amino]-5-(3,4-dimethoxyphenyl)pyridine-3-carbonitrile BDBM25543 4-arylamino-3-pyridinecarbonitrile, 4a
4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid octylamide CHEMBL3349070 BDBM50025360
8-imino-N-methyl-2-oxo-2H,8H-pyrano[2,3-f]chromene-9-carboxamide (4a) BDBM189362
BDBM246505 1-Phenyl-3-(4-(1,3,7,7-tetramethyl-5-oxo-1,2,3,4,5,6,7,8-octahydroquinazolin-4-yl)phenyl)urea (4a)
BDBM26626 CHEMBL183906 thiazolidine-2,4-dione, 4a (5Z)-5-{[3-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidine-2,4-dione
BDBM50021779 CHEMBL172961 3-(4a-Ethyl-1-methyl-2,4a,5,6,7,7a-hexahydro-1H-[1]pyrindin-4-yl)-phenol
BDBM50025335 4a,6a-Dimethyl-7-(2-methyl-butyryl)-hexadecahydro-indeno[5,4-f]quinolin-2-one CHEMBL3349137
BDBM50025367 CHEMBL3349118 4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid amide
BDBM50025444 CHEMBL3349072 7-(1-Hydroxy-ethyl)-4a,6a-dimethyl-hexadecahydro-indeno[5,4-f]quinolin-2-one
BDBM50142863 CHEMBL298778 [2-((4aS,10aR)-6-Methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-amine
BDBM50276434 CHEMBL510216 (2R,4aR,10aR)-4a-Propyl-2-prop-1-ynyl-1,2,3,4,4a,9,10,10aoctahydro-phenanthrene-2,7-diol
BDBM50304418 cis-4-(3,4-Dimethoxyphenyl)-2-[3-(morpholinomethyl)benzyl]-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one CHEMBL596394
BDBM50304419 CHEMBL592931 cis-4-(3,4-Dimethoxyphenyl)-2-[2-(morpholinomethyl)benzyl]-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
CHEMBL109676 BDBM50283390 21-(2-Cyclohexyl-ethyl)-7,7-dimethyl-hexadecahydro-9,22-dioxa-4a-aza-benzocyclohenicosene-5,6,10,23-tetraone
CHEMBL182687 BDBM50157853 5-Chloro-3-hydroxy-4a,8a-dihydro-1H-quinazoline-2,4-dione US11253521, No. 11
CHEMBL3349075 BDBM50025341 4a,6a-Dimethyl-7-(3-methyl-butyryl)-hexadecahydro-indeno[5,4-f]quinolin-2-one
CHEMBL336113 BDBM50133384 N4-(3-methylphenyl)-4,6-quinazolinediamine N*4*-m-Tolyl-quinazoline-4,6-diamine Anilinoquinazoline, 4a
CHEMBL423528 BDBM50053921 4-Hydroxy-3-(1-phenyl-propyl)-4a,5,6,7,8,9,10,10a-octahydro-cycloocta[b]pyran-2-one
CHEMBL456215 BDBM50276436 (4aS,10aR)-4a-(2-Hydroxyethyl)-2-prop-1-ynyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol
CHEMBL595272 BDBM50304423 cis-4-(3,4-Dimethoxyphenyl)-2-[4-(morpholinomethyl)benzyl]-4a,5,6,7,8,8a-hexahydrophthalazin-1(2H)-one
cid_6603550 12b-Methyl-1,3,4,5,6,7,12,12b-octahydro-2H-4a,12-diaza-dibenzo[a,e]azulene MLS000029301 BDBM87614 SMR000011434
cis-(+)-4-(3,4-Dimethoxyphenyl)-2-[4-(morpholinomethyl)benzyl]-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one BDBM50304424 CHEMBL593656
cis-(+/-)-4a-Ethyl-2-(4-fluorobenzyl)-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ol CHEMBL592301 BDBM50308921
cis-(+/-)-4a-Ethyl-2-(4-nitrophenethyl)-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ol BDBM50308916 CHEMBL592300
rac-4a-Methyl-4,4a,5,6-tetrahydro-2H-1,2,7,7a-tetraaza-benzo[c]fluoren-3-one CHEMBL1779431 BDBM50344313
thiol-arylsulfonamide, 4a 1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}azetidine-3-thiol BDBM26542
4,4-Dimethoxy-3,3-di(methoxycarbonyl)-5,5-dimethyl-1,1-diphenyl-1-heptene Alkenyldiarylmethane (ADAM) 4a Alkenyldiarylmethanes (ADAM) 4a BDBM2765 methyl 2-methoxy-5-{1-[4-methoxy-3-(methoxycarbonyl)-5-methylphenyl]hept-1-en-1-yl}-3-methylbenzoate
BDBM77980 MLS000041728 SMR000044398 2-[1-(1,3-benzodioxol-5-yl)-4a-oxidanyl-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-N-(2,4-dimethylphenyl)ethanamide 2-[1-(1,3-benzodioxol-5-yl)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-N-(2,4-dimethylphenyl)acetamide cid_663660
4-(dimethylamino)-6-methyl-6,10,12a-tris(oxidanyl)-1,3,11,12-tetrakis(oxidanylidene)-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 4-(dimethylamino)-6,10,12a-trihydroxy-1,3,11,12-tetraketo-6-methyl-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide BRD-A88208128-003-01-2 cid_44247471 4-(dimethylamino)-6,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide BDBM54850
cid_16717706 iron;1,2,3,4,5-pentamethylcyclopenta-1,3-diene;4-pyrrolidin-1-yl-6,7-dihydro-5H-cyclopenta[b]pyridine-4a,5,6,7,7a-pentaide BDBM88125 SMR000451233 iron;1,2,3,4,5-pentamethylcyclopenta-1,3-diene;4-pyrrolidino-6,7-dihydro-5H-1-pyrindine-4a,5,6,7,7a-pentaide (R)-(+)-4-Pyrrolidinopyrindinyl(pentamethylcyclopentadienyl)iron MLS000766813 iron;1,2,3,4,5-pentamethylcyclopenta-1,3-diene;4-(1-pyrrolidinyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-4a,5,6,7,7a-pentaide
methyl 2-[2-[1-(2,5-dimethoxyphenyl)-4a-oxidanyl-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]ethanoylamino]-4,5-dimethyl-thiophene-3-carboxylate cid_4360051 MLS000580409 SMR000220579 2-{2-[1-(2,5-Dimethoxy-phenyl)-4a-hydroxy-octahydro-isoquinolin-2-yl]-acetylamino}-4,5-dimethyl-thiophene-3-carboxylic acid methyl ester BDBM83772 2-[[2-[1-(2,5-dimethoxyphenyl)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-1-oxoethyl]amino]-4,5-dimethyl-3-thiophenecarboxylic acid methyl ester 2-[[2-[1-(2,5-dimethoxyphenyl)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]acetyl]amino]-4,5-dimethyl-thiophene-3-carboxylic acid methyl ester methyl 2-[[2-[1-(2,5-dimethoxyphenyl)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]acetyl]amino]-4,5-dimethylthiophene-3-carboxylate
methyl 2-[[2-[4a-hydroxy-1-(2-methoxyphenyl)-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]acetyl]amino]-4,5-dimethylthiophene-3-carboxylate MLS000580406 2-[[2-[4a-hydroxy-1-(2-methoxyphenyl)-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]acetyl]amino]-4,5-dimethyl-thiophene-3-carboxylic acid methyl ester SMR000220550 cid_3349218 2-{2-[4a-Hydroxy-1-(2-methoxy-phenyl)-octahydro-isoquinolin-2-yl]-acetylamino}-4,5-dimethyl-thiophene-3-carboxylic acid methyl ester BDBM90160 2-[[2-[4a-hydroxy-1-(2-methoxyphenyl)-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-1-oxoethyl]amino]-4,5-dimethyl-3-thiophenecarboxylic acid methyl ester methyl 2-[2-[1-(2-methoxyphenyl)-4a-oxidanyl-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]ethanoylamino]-4,5-dimethyl-thiophene-3-carboxylate
(4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-6b-fluoromethylsulfanyl-5-hydroxy-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one BDBM50054962 CHEMBL344512
(4aS,4bR,5S,6aS,6bR,8R,9aR)-6b-Ethylsulfanyl-4b-fluoro-5-hydroxy-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one BDBM50054963 CHEMBL143729
(4aS,4bR,5S,6aS,6bR,9aR)-4b-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-6b-(pyridin-2-ylsulfanyl)-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one CHEMBL435878 BDBM50054951
(4aS,4bR,5S,6aS,6bR,9aR,12S)-4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-6b-methylsulfanyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one BDBM50054961 CHEMBL144551
BDBM385450 4-((R or S)-1-(2- chloro-6-cyclopropyl- 3-fluorobenzoyl)-6- ((R)-3- (dimethylamino) pyrrolidine-1-carbonyl)- 4,5,6,7-tetrahydro- 1H-indazol-3- yl)cyclohex-3-ene-1- carboxylic acid US10689369, Example 4A US10287272, Example 4A
BDBM50054966 CHEMBL343438 (4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-5-hydroxy-4a,6a-dimethyl-6b-methylsulfanyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one
BDBM50054967 CHEMBL146781 (4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-5-hydroxy-6b-isopropylsulfanyl-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one
CHEMBL436070 BDBM50054952 (4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-5-hydroxy-6b-methanesulfinyl-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one
(11E,13E)-7,7-Dimethyl-1,3,4,7,8,16,17,18,19,20,21,23a-dodecahydro-2H,15H-9,22-dioxa-4a-aza-benzocyclohenicosene-5,6,10,23-tetraone BDBM50283389 CHEMBL111691
(2S,4R,4aR,10aR)-4a-Ethyl-2-prop-1-ynyl-1,2,3,4,4a,9,10,10aoctahydro-phenanthrene-2,4,7-triol CHEMBL457242 BDBM50276473
(4R,4aS)-4,8-Dihydroxy-6-methyl-9-oxo-4,9-dihydro-xanthene-4a-carboxylic acid methylamide CHEMBL92495 BDBM50081426
(4aR,6S,8aR)-8a-Methyl-2,4,5,6,7,8,8a,8b-octahydro-1H-cyclobuta[a]naphthalene-4a,6-diol BDBM50055277 CHEMBL150175
2-(1-propylazetidin-3-yl)-1H-1,3-benzodiazole-4-carboxamide BDBM27104 cyclic amine-containing benzimidazole carboxamide, 4a
3,3,4,4,4-Pentafluoro-1-((2S,4aS,8aS)-4a-methyl-decahydro-naphthalen-2-yl)-butan-2-one CHEMBL417184 BDBM50287473
6-dialkylamino-4-trifluoromethylquinolin-2(1H)-one, 4a 6-(propylamino)-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one BDBM18527
BDBM19181 3-phenyl-4aH,9H,9aH-indeno[1,2-e][1,2,4]triazin-9-one Aza-heterocyclic Derivative, 4a
BDBM222258 (Z)-4-(2-((E)-4-(2-chlorophenyl)-1-morpholino-2-oxobut-3-enylidene)hydrazinyl) benzenesulfonamide (4a)
BDBM50025349 CHEMBL3349289 1',4a',10'-trimethyl-(10'R)-spiro[tetrahydrofuran-2,7'-perhydroindeno[5,4-f]quinoline]-2'-one
BDBM50025404 CHEMBL3349143 4a,6a-Dimethyl-7-(1H-pyrrole-2-carbonyl)-hexadecahydro-indeno[5,4-f]quinolin-2-one
BDBM50025453 CHEMBL3349127 Sodium; 2-(4a,6a-dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinolin-7-yl)-propionate
BDBM50081429 (4R,4aS)-4,8-Dihydroxy-6-methyl-9-oxo-4,9-dihydro-xanthene-4a-carboxylic acid amide CHEMBL88409
BDBM50276168 CHEMBL470785 (2R,4aR,10aR)-4a-Allyl-2-prop-1-ynyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-2,7-diol
BDBM50283387 (11E,13Z)-7,7-Dimethyl-1,3,4,7,8,16,17,18,19,20,21,23a-dodecahydro-2H,15H-9,22-dioxa-4a-aza-benzocyclohenicosene-5,6,10,23-tetraone CHEMBL111188
BDBM50300366 CHEMBL582929 4aR,9aS-(+)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ol
BDBM50304416 cis-4-(3,4-Dimethoxyphenyl)-2-{4-[(dimethylamino)-methyl]benzyl}-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one CHEMBL595039
BDBM53494 cid_615939 MLS000033810 1,2,3,5,6,7-Hexahydro-9-thia-4a,8-diaza-cyclopenta[a]-s-indacen-4-one SMR000012745
BDBM615699 US20230271954, Compound 4A cis-N-4-((cyclopropylmethyl)(phenyl)amino) cyclohexyl)-2-methyl-1H-indole-3-carboxamide
BDBM667393 N-((4- ethylphenyl)(phenyl)methyl)- 2-oxo-6-(trifluoromethyl)- 1,2-dihydropyridine-3- carboxamide US11957687, Compound 4A
BDBM752292 1'-(2-(4-chlorophenyl)acetyl)-2-oxospiro[indoline-3,4'-piperidine]-5-carboxylic acid US20250197396, Compound 4a
CHEMBL182853 5-[Hydroxy-(3,4,5-trimethoxy-phenyl)-methyl]-4a-methyl-4,4a,5,6,7,8-hexahydro-3H-naphthalen-2-one BDBM50153505
CHEMBL274445 6,9-Dibenzyl-12-(6-oxiranyl-6-oxo-hexyl)-decahydro-4a,7,10,13-tetraaza-benzocyclododecene-5,8,11,14-tetraone BDBM50134805
CHEMBL288982 BDBM50287474 3,3-Difluoro-1-((2S,4aS,8aS)-4a-methyl-decahydro-naphthalen-2-yl)-pentadecan-2-one
CHEMBL3349168 BDBM50025455 4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide
CHEMBL377321 BDBM50186811 4a-(3'-cyano-biphenyl-4-yl)-N-(3,4-difluoro-phenyl)-4-piperidin-4-yl-butyramide
CHEMBL568076 4aR,9aS-(+)-cis-4a-Ethyl-2-phenylethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ol BDBM50300365
Step 1: 2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (4a) BDBM724027 US20250066290, Example 4
US9968610, Compound C-4 BDBM287588 US10420768, Compound C-4 US11752155, Compound C-4A' US9567341, Compound C-4
TAN-67 BDBM50290872 Tan-67 (racemic) CHEMBL327745 SB-213698 (-)-rel-3-((4aR,12aS)-2-methyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol 3-((4aS,12aR)-2-Methyl-1,3,4,5,12,12a-hexahydro-2H-2,6-diaza-naphthacen-4a-yl)-phenol
6-(6-aminopurin-9-yl)-2-ethoxy-2-oxidanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol SMR000450983 6-(6-aminopurin-9-yl)-2-ethoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-ol 6-adenin-9-yl-2-ethoxy-2-keto-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-ol BDBM81287 cid_4132952 6-(6-aminopurin-9-yl)-2-ethoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol MLS000766286
(4R,12aS)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride MLS000028367 SMR000058620 BDBM115113 (4R,12aS)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-diketo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride cid_54686763 (4R,12aS)-4,7-bis(dimethylamino)-1,10,11,12a-tetrakis(oxidanyl)-3,12-bis(oxidanylidene)-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride MINOCYCLINE HYDROCHLORIDE
cid_665407 MLS000041949 N-[(1S)-2-[(4aS,8aS)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-1-benzyl-2-keto-ethyl]-4-methoxy-benzenesulfonamide N-[(2S)-1-[(4aS,8aS)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-1-oxo-3-phenylpropan-2-yl]-4-methoxybenzenesulfonamide BDBM71698 N-[(2S)-1-[(4aS,8aS)-4a-oxidanyl-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-1-oxidanylidene-3-phenyl-propan-2-yl]-4-methoxy-benzenesulfonamide SMR000046528
(4aS,4bR,5S,6aS,6bR,8R,9aR,12S)-4b,12-Difluoro-5-hydroxy-4a,6a-dimethyl-6b-methylsulfanyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one CHEMBL342304 BDBM50054960
(4aS,4bR,5S,6aS,6bR,8R,9aR,12S)-4b,12-Difluoro-6b-fluoromethylsulfanyl-5-hydroxy-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one BDBM50054964 CHEMBL144319
CHEMBL144841 BDBM50054957 (4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-5-hydroxy-4a,6a-dimethyl-8-propyl-6b-(pyridin-2-ylsulfanyl)-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one
(2S)-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-6-ol racemic mixture Benzopyran derivative., 4a(racemate) BDBM19970
(4R,4aS)-4,8-Dihydroxy-6-methyl-9-oxo-4,9-dihydro-xanthene-4a-carboxylic acid methyl ester BDBM50081427 CHEMBL91382
(4aR,6S,8aR)-4a-Mercapto-8a-methyl-1,2,4,4a,5,6,7,8,8a,8b-decahydro-cyclobuta[a]naphthalen-6-ol CHEMBL150225 BDBM50055275
2-fluoro-9-oxo-N-(2-phenylpropan-2-yl)-9,10-dihydroacridine-3-carboxamide Acridone-Based Inhibitor, 4a BDBM19277
3,5-bis((5-bromo-6-methyl-2-morpholinopyrimidin-4-yl)thio)-4H-1,2,4-triazol-4-amine (4a) BDBM152742
3-((4aS,10aS)-10a-Methyl-2-phenethyl-1,3,4,5,10,10a-hexahydro-2H-benzo[g]isoquinolin-4a-yl)-phenol CHEMBL107398 BDBM50072452
BDBM15036 N-{5-[(2S)-2-amino-3-phenylpropoxy]pyridin-3-yl}pyridine-4-carboxamide pyridine-base inhibitor 4a
BDBM189381 3-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)oxazolo[4,5-b]pyridin-2(3H)-one (4a)
BDBM36392 (1R,4R,5R,7R,8R)-2-Benzyl-5-(hydroxymethyl)-2-azabicyclo[2.2.2]octane-4,7,8-triol, 4a CID10016442
BDBM50053913 CHEMBL133951 3-(2,2-Dimethyl-1-phenyl-propyl)-4-hydroxy-4a,5,6,7,8,9,10,10a-octahydro-cycloocta[b]pyran-2-one
BDBM50055271 (4aR,6S,8aR)-4a-Hydroxymethyl-8a-methyl-1,2,4,4a,5,6,7,8,8a,8b-decahydro-cyclobuta[a]naphthalen-6-ol CHEMBL146598
BDBM50055273 CHEMBL149955 (4aR,6S,8aR)-6-Hydroxy-8a-methyl-2,4,5,6,7,8,8a,8b-octahydro-1H-cyclobuta[a]naphthalene-4a-carbonitrile
BDBM50055274 (4aR,6S,8aR)-6-Hydroxy-8a-methyl-2,4,5,6,7,8,8a,8b-octahydro-1H-cyclobuta[a]naphthalene-4a-carbaldehyde CHEMBL148786
BDBM5882 3-[4-(1-oxo-2,3-dihydro-1H-isoindol-4-yl)phenyl]-1-phenylurea CHEMBL185477 isoindolinone analog 4a
BDBM82184 3-(2-{4-[(2,3-dimethoxyphenyl)carbonyl]piperidin-1-yl}ethyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one, 4a
CHEMBL1779432 BDBM50344314 rac-2-Benzyl-4a-methyl-4,4a,5,6-tetrahydro-2H-1,2,7,7a-tetraaza-benzo[c]fluoren-3-one
CHEMBL298997 BDBM50142867 2-{[2-((4aS,10aR)-6-Methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-amino}-ethanol
CHEMBL3349099 1-Formylamino-4a,6a-dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid diethylamide BDBM50025391
CHEMBL3349154 4-Methoxy-4a,6a-dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid amide BDBM50025354
CHEMBL340181 (4aR,6aR)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-hexadecahydro-indeno[5,4-f]quinolin-2-one BDBM50037923
cis-4-(3,4-Dimethoxyphenyl)-2-[4-(piperidin-1-ylmethyl)benzyl]-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one CHEMBL603626 BDBM50304414
(2E,12aS)-2-[amino(hydroxy)methylene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride (2E,12aS)-2-[azanyl(oxidanyl)methylidene]-4,7-bis(dimethylamino)-10,11,12a-tris(oxidanyl)-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride Minocycline hydrochloride (2E,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride SMR000326784 BDBM52989 MLS000859923 cid_23640912
2,4-Disubstituted Pyrimidine 4a 4-(2-phenyl-1H-imidazol-1-yl)-N-(pyridin-2-yl)pyrimidin-2-amine BDBM5393
6-Alkyl 1,4-Diene Steroid 4a BDBM9947 (8R)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,14-dione
BDBM18516 6-(1-Pyrrolidine)quinolin-2(1H)-one, 4a 6-(pyrrolidin-1-yl)-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one
BDBM222405 3-(1-Phenyl-1H-[1,2,3]triazol-4-yl)-N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)propanamide (4a)
BDBM50017237 CHEMBL304616 (4aS,9aR)-4a-Ethyl-2-propyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol
BDBM50055268 CHEMBL149710 (4aR,6S,8aR)-6-Hydroxy-8a-methyl-2,4,5,6,7,8,8a,8b-octahydro-1H-cyclobuta[a]naphthalene-4a-carboxylic acid
BDBM50142875 [2-((4aS,10aR)-6-Methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-carbamic acid ethyl ester CHEMBL301487
BDBM50293756 CHEMBL561696 2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide KSP Inhibitor, 4a
CHEMBL102000 (2,4-Dichloro-5-methoxy-phenyl)-(7,8-dimethoxy-4a,5,10,10a-tetrahydro-pyrimido[4,5-b]quinolin-4-yl)-amine BDBM50132160
CHEMBL136413 3-{1-[(Butyl-ethyl-amino)-methyl]-2-oxo-propyl}-4-hydroxy-4a,8a-dihydro-chromen-2-one BDBM50133912
CHEMBL194490 BDBM50166505 3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)-4a,5,6,7,8,8a-hexahydro-3H-quinazolin-4-one
CHEMBL302977 (4aS,9aR)-2-Cyclopentylmethyl-4a-ethyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol BDBM50017240
CHEMBL347294 BDBM50055278 (4aR,6S,8aR)-6-Hydroxy-8a-methyl-2,4,5,6,7,8,8a,8b-octahydro-1H-cyclobuta[a]naphthalene-4a-carbaldehyde oxime
CHEMBL426262 5-(Benzo[b]thiophen-3-yl-hydroxy-methyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-3H-naphthalen-2-one BDBM50153518
CHEMBL506844 (2R,4aR,10aR)-4a-Ethyl-7-(2-methylpyridin-3-ylmethoxy)-2-phenyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-2-ol BDBM50276475
CHEMBL69559 BDBM50017242 (4aS,9aR)-4a-Ethyl-2,9a-dimethyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol
Urea-based Analogue, 4a (1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}phenyl)carbonyl]cyclopentane-1-carboxylic acid BDBM20716
cid_801122 MLS000554543 SMR000171575 4-(4-Hydroxy-phenylamino)-2,3-dihydro-1H-4a,9-diaza-cyclopenta[b]fluorene-10-carbonitrile BDBM56543
(2E,4R,12aR)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride (2E,4R,12aR)-2-[amino(hydroxy)methylene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride MLS000028367 SMR000058620 BDBM37534 (4R,12aS)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-diketo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride cid_6602603 (2E,4R,12aR)-2-[azanyl(oxidanyl)methylidene]-4,7-bis(dimethylamino)-10,11,12a-tris(oxidanyl)-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride MINOCYCLINE HYDROCHLORIDE
(3S,4aS)-2-keto-3-[2-keto-2-(veratrylamino)ethyl]-1-(1-naphthylmethyl)-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylic acid methyl ester (3S,4aS)-3-[2-[(3,4-dimethoxyphenyl)methylamino]-2-oxoethyl]-1-(1-naphthalenylmethyl)-2-oxo-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylic acid methyl ester methyl (3S,4aS)-3-[2-[(3,4-dimethoxyphenyl)methylamino]-2-oxidanylidene-ethyl]-1-(naphthalen-1-ylmethyl)-2-oxidanylidene-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylate BDBM95886 MLS003591135 cid_53301042 methyl (3S,4aS)-3-[2-[(3,4-dimethoxyphenyl)methylamino]-2-oxoethyl]-1-(naphthalen-1-ylmethyl)-2-oxo-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylate SMR002252430
BDBM96846 MLS003551973 methyl (3S,4aS)-1-benzyl-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylate (3S,4aS)-1-benzyl-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylic acid methyl ester (3S,4aS)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-1-(phenylmethyl)-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylic acid methyl ester methyl (3S,4aS)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-2-oxidanylidene-1-(phenylmethyl)-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylate cid_53300088 SMR002202718
BDBM96847 methyl (3S,4aS)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-1-octyl-2-oxidanylidene-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylate SMR002202741 (3S,4aS)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-1-octyl-2-oxo-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylic acid methyl ester (3S,4aS)-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-1-octyl-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylic acid methyl ester MLS003551996 methyl (3S,4aS)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-1-octyl-2-oxo-3,4,5,6,7,8-hexahydrocyclohepta[b]pyridine-4a-carboxylate cid_53300195
7-[(5,5-dimethyl-3-oxidanylidene-cyclohexen-1-yl)amino]-2-phenyl-4a,8a-dihydro-4H-pyrano[3,2-d][1,3]dioxin-6-one BDBM72292 7-[(5,5-dimethyl-3-oxo-1-cyclohexenyl)amino]-2-phenyl-4a,8a-dihydro-4H-pyrano[3,2-d][1,3]dioxin-6-one 7-[(5,5-dimethyl-3-oxo-1-cyclohexen-1-yl)amino]-2-phenyl-4a,8a-dihydropyrano[3,2-d][1,3]dioxin-6(4H)-one cid_11842308 MLS000699898 7-[(5,5-dimethyl-3-oxocyclohexen-1-yl)amino]-2-phenyl-4a,8a-dihydro-4H-pyrano[3,2-d][1,3]dioxin-6-one SMR000230329 7-[(3-keto-5,5-dimethyl-cyclohexen-1-yl)amino]-2-phenyl-4a,8a-dihydro-4H-pyrano[3,2-d][1,3]dioxin-6-one
(1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-ylamine CHEMBL404524 BDBM50233024
(4aR,6S,8aR)-6-Hydroxy-8a-methyl-2,4,5,6,7,8,8a,8b-octahydro-1H-cyclobuta[a]naphthalene-4a-carboxylic acid amide CHEMBL148676 BDBM50055276
(4aR,6aS,7S,11aR)-4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid diisopropylamide BDBM50101145 CHEMBL297697
(4aS,9aR)-2-Cyclobutylmethyl-4a-ethyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol; hydrochloride BDBM50017234 CHEMBL542150
3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl thiomorpholine-4-carboxylate (Prepared according to Scheme 5) US11485731, Example 4A BDBM579947
4-[(Pyridin-3-ylmethyl)-amino]-2,3-dihydro-1H-4a,9-diaza-cyclopenta[b]fluorene-10-carbonitrile BDBM29656 MLS000556361 cid_702038 SMR000147678
7-Hydroxy-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one CHEMBL583743 BDBM50025418
BDBM222223 N-Hydroxy-4-((4-((3-(hydroxyimino)-2-oxoindolin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)methyl)benzamide (4a)
BDBM50017238 (4aS,9aR)-2-Cyclopropylmethyl-4a-ethyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol; hydrochloride CHEMBL555891
BDBM50021195 2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexahydro-2H-11-oxa-4a-aza-benzo[a]fluoren-2-yl)-methyl-amide CHEMBL48603
BDBM50021197 2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexahydro-2H-11-oxa-4a-aza-benzo[a]fluoren-2-yl)-methyl-amide CHEMBL299595
BDBM50037920 CHEMBL340715 (4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-4a,6a,10-trimethyl-hexadecahydro-indeno[5,4-f]quinolin-2-one
BDBM50171747 CHEMBL193336 2-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-4a,5,6,7,8,8a-hexahydro-3H-quinazolin-4-one
BDBM50172193 CHEMBL196145 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid phenethyl-amide
BDBM50175519 (4S,5R)-5-((S)-2-Mercapto-3-phenyl-propionylamino)-octahydro-9-thia-4a-aza-benzocycloheptene-4-carboxylic acid CHEMBL372307
BDBM50276127 (2R,3S,4aR,10aR)-4a-Ethyl-7-(2-methylpyridin-3-ylmethoxy)-2-phenyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,3-diol CHEMBL470783
BDBM50276437 CHEMBL457035 (2R,4aR,10aR)-4a-Ethyl-2-prop-1-ynyl-7-(pyridin-4-ylmethoxy)-1,2,3,4,4a,9,10,10a-octahydrophenanthren-2-ol
BDBM50304415 cis-4-(3,4-Dimethoxyphenyl)-2-{4-[(4-methylpiperazin-1-yl)methyl]benzyl}-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one CHEMBL595038
BDBM8613 (4-Pyridylmethylene)tetrahydronaphthalene 4a 4-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemethyl]pyridine 4-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]pyridine
CHEMBL196509 1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazole-5,2'-(dihydro[1,3]dioxolane)] BDBM50167808
CHEMBL48558 BDBM50021196 2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexahydro-2H-11-oxa-4a-aza-benzo[a]fluoren-2-yl)-methyl-amide
CHEMBL594109 cis-2-{4-[(1H-Imidazol-1-yl)methyl]benzyl}-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one BDBM50304411
CHEMBL595064 BDBM50304412 cis-4-(3,4-Dimethoxyphenyl)-2-{4-[(4-oxopiperidin-1-yl)-methyl]benzyl}-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
CHEMBL89464 BDBM50081428 (4R,4aS)-4,8-Dihydroxy-6-methyl-9-oxo-4,9-dihydro-xanthene-4a-carboxylic acid (2-hydroxy-ethyl)-amide
Cancer Chemotherapy National Service Center (CCNSC) compound 112500 1,8a-dihydroxy-4a,5,6-trimethyl-decahydronaphthalen-2-yl acetate BDBM507 NSC 112500
N-[3-((6S,19R,21aR)-6-Benzyl-5,8,17,18,21-pentaoxo-docosahydro-4a,7,16,20-tetraaza-benzocyclononadecen-19-yl)-propyl]-guanidine CHEMBL328200 BDBM50288450
US9303033, Example 275, Table 52, Compound 1 US9303033, C39, Table 43A, Compound 6 US9303033, R1, Table 4A, Compound 12 BDBM218860
(4aR,5R,6aS,6bR,10S,12aR)-5,10-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid echinocystic aicd (4aR,5R,6aS,6bR,10S,12aR)-2,2,6a,6b,9,9,12a-heptamethyl-5,10-bis(oxidanyl)-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid cid_23983726 SMR001397236 BDBM75554 MLS002473143
BDBM342439 N-(2-((4a′R,8a′R)-2′-amino-4a′,5′-dihydro-4′H-spiro[cyclobutane-1,6′-pyrano 3,4-d][1,3]oxazin]-8a′(8′H)-yl)thiazol-4-yl)-5-(difluoromethoxy)picolinamide US9771379, Example 14
(2R,4aR,10aR)-4a-Ethyl-7-(2-methylpyridin-3-ylmethoxy)-2-prop-1-ynyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-2-ol BDBM50276438 CHEMBL457036
(2S,3S)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxo-3-phenylbutan-2-aminium; 2,2,2-trifluoroacetate 3-(S)-fluoropyrrolidide 4a BDBM11467
(3Z)-2-oxo-3-[1-(1H-pyrrol-2-yl)ethylidene]-2,3-dihydro-1H-indole-5-sulfonamide BDBM17040 Indolinone based inhibitor, 4a
(4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid adamantan-2-ylamide CHEMBL194409 BDBM50172188
(4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-10-ethyl-4a,6a-dimethyl-hexadecahydro-indeno[5,4-f]quinolin-2-one BDBM50037913 CHEMBL340684
(4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-10-propyl-hexadecahydro-indeno[5,4-f]quinolin-2-one CHEMBL414427 BDBM50037929
1H,1''H-[3,3':3',3''-terindol]-2'(1'H)-one (4a) BDBM225281
4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(3-hydroxyazetidin-1-yl)-1H-indazol-3-yl)benzoic acid BDBM336531 US9745265, 4A
BDBM14806 furanopyrimidine compound 8 DFP-4A 5,6-diphenylfuro[2,3-d]pyrimidin-4-amine 5,6-Diphenyl-furo[2,3-d]pyrimidin-4 -ylamine
BDBM20878 O-glucoside, 4a (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methoxyphenyl)methyl]phenoxy}oxane-3,4,5-triol CHEMBL270766
BDBM50032395 CHEMBL100718 1-{2-[2-(Benzyl-methyl-amino)-ethoxy]-ethyl}-3-(9,10-dioxo-4a,9,9a,10-tetrahydro-anthracene-2-carbonyl)-thiourea
BDBM50057485 1-((4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carbonyl)-1,3-diisopropyl-urea CHEMBL278860
BDBM50132154 (2,4-Dichloro-phenyl)-[7-methoxy-8-(2-methoxy-ethoxy)-4a,5,10,10a-tetrahydro-pyrimido[4,5-b]quinolin-4-yl]-amine CHEMBL322689
BDBM50142872 {[2-((4aS,10aR)-6-Methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-amino}-acetic acid tert-butyl ester CHEMBL51146
BDBM50172200 CHEMBL199255 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid adamantan-1-ylamide
BDBM50291651 4-[2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-[2-(4a,5,6,7,8,8a-hexahydro-naphthalen-1-yl)-ethylcarbamoyl]-butyric acid CHEMBL268031
BDBM50304409 CHEMBL595959 cis-2-{2-[2-(1H-Imidazol-1-yl)ethoxy]ethyl}-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
BDBM5266 (2S,3S,4R)-4-carbamimidamido-2-(dipropylcarbamoyl)-3-acetamido-3,4-dihydro-2H-pyran-6-carboxylic acid Benzoic Acid Inhibitor 4a
CHEMBL124803 (4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-10-phenyl-hexadecahydro-indeno[5,4-f]quinolin-2-one BDBM50037928
CHEMBL1272187 5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulfonamide N-alkylated benzimidazole derivative, 4a BDBM50329832 carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 4
CHEMBL132577 4-Cyano-N-{3-[1-(4-hydroxy-2-oxo-4a,5,6,7,8,8a-hexahydro-2H-chromen-3-yl)-propyl]-phenyl}-benzenesulfonamide BDBM50053905
CHEMBL403139 N-((1S,13bR)-6-chloro-1,2,3,4,9,13b-hexahydro-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide BDBM50233007
CHEMBL54784 Pyrido[4,3-d]pyrimidine 4a BDBM3587 N-benzylpyrido[4,3-d]pyrimidin-4-amine 4-[(Phenylmethyl)amino]-pyrido[4,3-d]pyrimidine
CHEMBL83625 BDBM50036920 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one
N-(1-Benzyl-piperidin-4-yl)-2-(7-hydroxy-2-oxo-4a,8a-dihydro-2H-chromen-4-yl)-acetamide BDBM50107193 CHEMBL136163
[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-phenyl-methanol CHEMBL181601 BDBM50153509
benzyl 2,2,6a,6b,9,9,13a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,13,13a,13b,14,15b-octadecahydropiceno[2,3-c][1,2,5]oxadiazole-4a-carboxylate BDBM50184612 CHEMBL206898
cid_935894 SMR000148265 BDBM40225 5,6-Dioxo-3,4-dihydro-2H,5H,6H-11-oxa-1-thia-4a,12-diaza-naphthacene-8-carbaldehyde MLS000557348
BDBM342440 N-(2-((4a′R,8a′R)-2′-amino-4a′,5′-dihydro-4′H-spiro[cyclobutane-1,6′-pyrano[3,4-d][1,3]oxazin]-8a′(8′H)-yl)thiazol-4-yl)-5-(difluoromethoxy)-3-methyl picolinamide US9771379, Example 15
(3S,4aR)-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-6,6-dimethyl-1-piperonyl-3,4,5,7-tetrahydroquinoline-4a-carboxylic acid methyl ester methyl (3S,4aR)-1-(1,3-benzodioxol-5-ylmethyl)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-6,6-dimethyl-2-oxo-3,4,5,7-tetrahydroquinoline-4a-carboxylate MLS003674940 (3S,4aR)-1-(1,3-benzodioxol-5-ylmethyl)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-6,6-dimethyl-2-oxo-3,4,5,7-tetrahydroquinoline-4a-carboxylic acid methyl ester methyl (3S,4aR)-1-(1,3-benzodioxol-5-ylmethyl)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-6,6-dimethyl-2-oxidanylidene-3,4,5,7-tetrahydroquinoline-4a-carboxylate cid_53383948 SMR002354236 BDBM96854
(3S,4aS)-1-[(2,4-dichlorophenyl)methyl]-3-[2-(4-ethoxycarbonyl-1-piperazinyl)-2-oxoethyl]-2-oxo-3,4,5,6-tetrahydrocyclopenta[b]pyridine-4a-carboxylic acid ethyl ester cid_53300224 MLS003552027 SMR002202772 ethyl (3S,4aS)-1-[(2,4-dichlorophenyl)methyl]-3-[2-(4-ethoxycarbonylpiperazin-1-yl)-2-oxidanylidene-ethyl]-2-oxidanylidene-3,4,5,6-tetrahydrocyclopenta[b]pyridine-4a-carboxylate (3S,4aS)-3-[2-(4-carbethoxypiperazino)-2-keto-ethyl]-1-(2,4-dichlorobenzyl)-2-keto-3,4,5,6-tetrahydro-1-pyrindine-4a-carboxylic acid ethyl ester ethyl (3S,4aS)-1-[(2,4-dichlorophenyl)methyl]-3-[2-(4-ethoxycarbonylpiperazin-1-yl)-2-oxoethyl]-2-oxo-3,4,5,6-tetrahydrocyclopenta[b]pyridine-4a-carboxylate BDBM94566
(3S,4aS)-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-1-piperonyl-3,4,5,6-tetrahydro-1-pyrindine-4a-carboxylic acid ethyl ester ethyl (3S,4aS)-1-(1,3-benzodioxol-5-ylmethyl)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-3,4,5,6-tetrahydrocyclopenta[b]pyridine-4a-carboxylate (3S,4aS)-1-(1,3-benzodioxol-5-ylmethyl)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-3,4,5,6-tetrahydrocyclopenta[b]pyridine-4a-carboxylic acid ethyl ester cid_53300042 SMR002202672 MLS003551927 ethyl (3S,4aS)-1-(1,3-benzodioxol-5-ylmethyl)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-2-oxidanylidene-3,4,5,6-tetrahydrocyclopenta[b]pyridine-4a-carboxylate BDBM96844
(4R,4aS,6E,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-6-(phenylmethylidene)-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride SMR001338896 (4R,4aS,6E,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-6-(phenylmethylene)-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride BDBM67397 (4R,4aS,6E,12bS)-6-benzylidene-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride 7-Benzylidene-7-dehydronaltrexone (BNTX) hydrochloride cid_44246746 MLS002320750 (4R,4aS,6E,12bS)-6-benzal-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
(4aR,6aR,6aS,6bR,8aS,12aS,14bS)-8a-(imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-4a,5,6,6a,7,8,9,10,12,12a-decahydropicene-2-carbonitrile MLS002702501 (4aR,6aR,6aS,6bR,8aS,12aS,14bS)-8a-imidazol-1-ylcarbonyl-4,4,6a,6b,11,11,14b-heptamethyl-3,13-bis(oxidanylidene)-4a,5,6,6a,7,8,9,10,12,12a-decahydropicene-2-carbonitrile BDBM80086 cid_9958995 (4aR,6aR,6aS,6bR,8aS,12aS,14bS)-8a-(imidazole-1-carbonyl)-3,13-diketo-4,4,6a,6b,11,11,14b-heptamethyl-4a,5,6,6a,7,8,9,10,12,12a-decahydropicene-2-carbonitrile SMR001566062 CDDO-Im, 1 (4aR,6aR,6aS,6bR,8aS,12aS,14bS)-8a-[1-imidazolyl(oxo)methyl]-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-4a,5,6,6a,7,8,9,10,12,12a-decahydropicene-2-carbonitrile
1-(9a-Hydroxy-6-methyl-2-thioxo-1,2,3,9a-tetrahydro-1,3,4,9-tetraaza-fluoren-9-yl)-propan-1-one MLS000121018 1-(4a-hydroxy-8-methyl-3-sulfanylidene-2,4-dihydro-[1,2,4]triazino[5,6-b]indol-5-yl)propan-1-one cid_3148083 1-(4a-hydroxy-8-methyl-3-sulfanylidene-2,4-dihydro-[1,2,4]triazino[5,6-b]indol-5-yl)-1-propanone 1-(8-methyl-4a-oxidanyl-3-sulfanylidene-2,4-dihydro-[1,2,4]triazino[5,6-b]indol-5-yl)propan-1-one SMR000118485 BDBM78625 1-(4a-hydroxy-8-methyl-3-thioxo-2,4-dihydro-[1,2,4]triazin[5,6-b]indol-5-yl)propan-1-one
7-hydroxy-7-methylol-1-(3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl)oxy-4a,7a-dihydro-1H-cyclopenta[c]pyran-4-carboxylic acid methyl ester BDBM82854 methyl 7-(hydroxymethyl)-1-[6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-7-oxidanyl-4a,7a-dihydro-1H-cyclopenta[c]pyran-4-carboxylate cid_100058 7-hydroxy-7-(hydroxymethyl)-1-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-4a,7a-dihydro-1H-cyclopenta[c]pyran-4-carboxylic acid methyl ester SMR000440681 MLS000877010 methyl 7-hydroxy-7-(hydroxymethyl)-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,7a-dihydro-1H-cyclopenta[c]pyran-4-carboxylate
Methacycline hydrochloride (4S,4aR,5S,5aS,12aS)-4-(dimethylamino)-5,10,12a-trihydroxy-6-methylidene-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride (4S,4aR,5S,5aS,12aS)-4-(dimethylamino)-5,10,12a-trihydroxy-1,3,11,12-tetraketo-6-methylene-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride SMR001307274 MLS002222335 cid_44246714 (4S,4aR,5S,5aS,12aS)-4-(dimethylamino)-6-methylidene-5,10,12a-tris(oxidanyl)-1,3,11,12-tetrakis(oxidanylidene)-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride (4S,4aR,5S,5aS,12aS)-4-(dimethylamino)-5,10,12a-trihydroxy-6-methylene-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride BDBM115147
cid_53383841 BDBM94182 MLS003674785 SMR002354081 (3S,4aS)-3-[2-(1-adamantylmethylamino)-2-oxoethyl]-1-[2-(1-cyclohexenyl)ethyl]-2-oxo-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylic acid ethyl ester ethyl (3S,4aS)-3-[2-(1-adamantylmethylamino)-2-oxidanylidene-ethyl]-1-[2-(cyclohexen-1-yl)ethyl]-2-oxidanylidene-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylate (3S,4aS)-3-[2-(1-adamantylmethylamino)-2-keto-ethyl]-1-[2-(cyclohexen-1-yl)ethyl]-2-keto-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylic acid ethyl ester ethyl (3S,4aS)-3-[2-(1-adamantylmethylamino)-2-oxoethyl]-1-[2-(cyclohexen-1-yl)ethyl]-2-oxo-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylate
ethyl (3S,4aS)-1-(1,3-benzodioxol-5-ylmethyl)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-2-oxidanylidene-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylate cid_53299953 MLS003551833 SMR002202578 BDBM96843 ethyl (3S,4aS)-1-(1,3-benzodioxol-5-ylmethyl)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylate (3S,4aS)-1-(1,3-benzodioxol-5-ylmethyl)-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylic acid ethyl ester (3S,4aS)-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-1-piperonyl-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylic acid ethyl ester
NALOXONE HYDROCHLORIDE MLS000069540 SMR000058766 (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride (4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride cid_5464092 (4R,4aS,7aR,12bS)-4a,9-bis(oxidanyl)-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride BDBM54795
Proscar BDBM50334788 (4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide CHEMBL710 FINASTERIDE 4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide(Finasteride) MK-906 (R)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide Propecia (4aR,6aS,7S,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide US9061023, Finasteride (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide (4aR,4bS,6aS,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide (4aR,6aS,11aR)-4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide 4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide (17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one 4a,6a,9a-Trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (Finasteride)
((1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-isobutyl-amine BDBM50233011 CHEMBL403205
(2R,3R,4S)-4-amino-2-[(2-aminoethyl)carbamoyl]-3-acetamido-3,4-dihydro-2H-pyran-6-carboxylic acid BDBM4923 carboxamide deriv. 4a
(2R,3S,4aR,10aR)-4a-Ethyl-7-(2-methylpyridin-3-ylmethoxy)-2-prop-1-ynyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,3-diol BDBM50276472 CHEMBL515671
(4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-1-ethyl-4a,6a,10-trimethyl-hexadecahydro-indeno[5,4-f]quinolin-2-one CHEMBL340305 BDBM50037922
(4aS,9aR)-4a-Ethyl-2-furan-3-ylmethyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol; hydrochloride BDBM50017239 CHEMBL542881
3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-5-(4-dimethylamino-naphthalen-1-yl)-4,5-dihydropyrazole-1-carbothioic acid amide (4a) BDBM153289
4-(2-{4-[3-(thiophen-3-yl)pyrazolo[1,5-a]pyrimidin-6-yl]phenoxy}ethyl)morpholine pyrazolo[1,5-a]pyrimidine 4a BDBM5409
4a,6a-Dimethyl-7-(3-methyl-butyryl)-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one CHEMBL3349151 BDBM50025451
4aR,9aS,2'R-(+)-cis-2-(2'-Hydroxy-2'-phenylethyl)-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ol CHEMBL566557 BDBM50300371
4aR,9aS,2'S-(+)-cis-2-(2'-Hydroxy-2'-phenylethyl)-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ol CHEMBL567213 BDBM50300364
5,7-Dihydroxy-4′-nitro-isoflavone (4a) 5,7‐dihydroxy‐3‐(4‐nitrophenyl)‐4H‐chromen‐4‐one BDBM106784
6-Methyl-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-4a,5,6,7,8,8a-hexahydro-3H-quinazolin-4-one CHEMBL198230 BDBM50171731
BDBM14450 1-({1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl}methyl)-4-(naphthalen-1-yl)-1H-pyrrole-3-carbonitrile pyrrole analog 4a
BDBM199129 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)-ethyl-5-(4-methoxyphenyl)-1-(p-tolyl)-1H-pyrazole-3-carboxylate (4a)
BDBM4494 6,7-Dimethoxyquinoline deriv. 6 N-(2,4-dichlorophenyl)-6,7-dimethoxyquinolin-4-amine quinazoline deriv. 4a (2,4-Dichlorophenyl)(6,7-dimethoxyquinolin-4-yl)-amine
BDBM50034156 CHEMBL16743 N-((4aR,6aS,7S,11aR)-4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinolin-7-yl)-N-methyl-formamide
BDBM50037930 CHEMBL127760 (4aR,6aR,10S)-1-Allyl-7-(1,5-dimethyl-hexyl)-4a,6a,10-trimethyl-hexadecahydro-indeno[5,4-f]quinolin-2-one
BDBM50142870 CHEMBL545668 [2-((4aS,10aR)-6-Methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-dimethyl-amine; compound with GENERIC INORGANIC NEUTRAL COMPONENT
BDBM50233027 CHEMBL404737 2,2,2-trifluoro-N-(1S,13bR)-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl-acetamide
BDBM50300368 CHEMBL566527 4aS,9aR,2'R-(-)-cis-2-(2'-Hydroxy-2-phenylethyl)-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ol
BDBM9965 6-Substituted Androst-4-ene Analog 4a (8S)-8-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-14-one
C-5 substituted oxindole inhibitor 4a (3Z)-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one BDBM10073
CHEMBL186954 [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-p-tolyl-methanol BDBM50153519
CHEMBL194404 BDBM50171746 6,6-Dimethyl-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-4a,5,6,7,8,8a-hexahydro-3H-quinazolin-4-one
CHEMBL3349156 BDBM50025338 4a,6a-Dimethyl-7-(2-methyl-butyryl)-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one
CHEMBL364511 BDBM50167803 1-(4-fluorophenyl)-4a,5',5'-trimethyl-(4aS)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro-4'H-[1,3]dioxane)]
CHEMBL454507 BDBM50254829 4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propylamino)pentyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
CHEMBL499461 BDBM50254830 4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propylamino)pentyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
CHEMBL552619 (4aS,9aR)-4a-Ethyl-2-furan-2-ylmethyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol; hydrochloride BDBM50017241
CHEMBL568309 4aS,9aR,2'S-(-)-cis-2-(2'-Hydroxy-2-phenylethyl)-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ol BDBM50300369
CHEMBL93351 BDBM50095116 (R)-1-(3-Amino-propyl)-6-(1H-indol-3-ylmethyl)-10-naphthalen-1-ylmethyl-octahydro-4a-aza-benzocyclononene-5,11-dione
N-((1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-acetamide CHEMBL253734 BDBM50233009
N-aryl-bicyclic hydantoin, 4a (1R,6R,7S)-4-(4-nitronaphthalen-1-yl)-2,4-diazatricyclo[5.2.1.0^{2,6}]decane-3,5-dione BDBM18162 CHEMBL185880
US10308629, Example 12 BDBM395250 rel-(4aR,5aR)-3-(Phenylamino)-2-(pyridin-4-yl)-4a,5,5a,6-tetrahydrocyclopropa[f]indol-4(1H)-one
US20240150293, Example 4 Example 4A 1″-methyldispiro[1,3-dioxolane-2,1′-cyclohexane-4′,3″-indole]-2″-one BDBM672874
cis-2-[(E)-4-(1H-Imidazol-1-yl)but-2-enyl]-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one CHEMBL594108 BDBM50304410
US11660306, Example Moronic acid SMR000232278 (4aS,6aR,6aR,6bR,8aR,12aR,14aS)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-4,5,6,6a,7,8,8a,11,12,13,14,14a-dodecahydro-3H-picene-4a-carboxylic acid MLS000563430 (4aS,6aR,6aR,6bR,8aR,12aR,14aS)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxidanylidene-4,5,6,6a,7,8,8a,11,12,13,14,14a-dodecahydro-3H-picene-4a-carboxylic acid (4aS,6aR,6aR,6bR,8aR,12aR,14aS)-10-keto-2,2,6a,6b,9,9,12a-heptamethyl-4,5,6,6a,7,8,8a,11,12,13,14,14a-dodecahydro-3H-picene-4a-carboxylic acid BDBM54263 cid_489941 MORONIC ACID
(4-Chloro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-methanol BDBM50153506 CHEMBL362556
(4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid bicyclo[2.2.1]hept-2-ylamide BDBM50172202 CHEMBL424831
1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-pentan-1-ol BDBM50153502 CHEMBL186683
2-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-4a,5,6,7,8,8a-hexahydro-3H-pyrido[4,3-d]pyrimidin-4-one BDBM50171740 CHEMBL370171
4-Cyano-N-{3-[1-(4-hydroxy-2-oxo-4a,5,6,7,8,9,10,10a-octahydro-2H-cycloocta[b]pyran-3-yl)-propyl]-phenyl}-benzenesulfonamide BDBM50053906 CHEMBL133804
4a,6a-Dimethyl-2-oxo-2,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid diisopropylamide BDBM50025435 CHEMBL573180
4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid amide BDBM50025340 CHEMBL572946
4a,6a-Dimethyl-7-(1H-pyrrole-2-carbonyl)-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one BDBM50025336 CHEMBL3349149
BDBM329717 (3S,4R)-1-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-4-fluoro-1H-indazol-3-yl)-3-methylpiperidine-4-carboxylic acid US9663522, 4A
BDBM489702 (R)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-1- yl)amino)-1-oxo-3-phenylpropan- 2-yl)benzamide US10968172, ID # 4a
BDBM50025423 4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid diisopropylamide CHEMBL3349158
BDBM50025448 4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid ethylamide CHEMBL567823
BDBM50132158 CHEMBL100172 (2,4-Dichloro-5-methoxy-phenyl)-[8-methoxy-7-(2-methoxy-ethoxy)-4a,5,10,10a-tetrahydro-pyrimido[4,5-b]quinolin-4-yl]-amine
BDBM50142871 Allyl-[2-((4aS,10aR)-6-methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-amine; compound with GENERIC INORGANIC NEUTRAL COMPONENT CHEMBL542123
BDBM50153501 CHEMBL184109 (4-Fluoro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-methanol
BDBM50153504 [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-(3-methoxy-phenyl)-methanol CHEMBL366093
BDBM50153511 CHEMBL362392 1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-2-phenyl-ethanol
BDBM50153515 1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-nonan-1-ol CHEMBL183475
BDBM50233021 N-((1S,13bR)-6-acetyl-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide CHEMBL252648
BDBM50290870 (4aR,8aR)-4a-(3-Hydroxy-phenyl)-3,7-dimethyl-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrrolo[3,2-g]isoquinoline-2-carboxylic acid diethylamide CHEMBL316863
BDBM50304413 CHEMBL596447 cis-2-[4-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-benzyl]-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
C3-Cyclic Amine Carbocyclic Analogue 4a (3R,4R,5S)-5-amino-3-(azetidin-1-yl)-4-acetamidocyclohex-1-ene-1-carboxylic acid BDBM5250
CHEMBL100551 BDBM50132153 (2,4-Dichloro-5-methoxy-phenyl)-[7-methoxy-8-(2-methoxy-ethoxy)-4a,5,10,10a-tetrahydro-pyrimido[4,5-b]quinolin-4-yl]-amine
CHEMBL184578 BDBM50153503 3-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-hydroxy-methyl}-phenol
CHEMBL186930 BDBM50153514 4-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-hydroxy-methyl}-phenol
CHEMBL186948 [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-naphthalen-2-yl-methanol BDBM50153507
CHEMBL24958 (4aR,6aR,7R,10S)-7-(1,5-Dimethyl-hexyl)-1-ethyl-4a,6a,10-trimethyl-hexadecahydro-indeno[5,4-f]quinolin-2-one BDBM50057454
CHEMBL403486 BDBM50233014 (rac)-N-(6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide
CHEMBL544292 BDBM50017235 (4aS,9aR)-4a-Ethyl-2-(tetrahydro-furan-2-ylmethyl)-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol; hydrochloride
N-[3-(1H-Imidazol-1-yl)propyl]-2-[cis-4-(3,4-dimethoxyphenyl)-1-oxo-4a,5,8,8a-tetrahydrophthalazin-2(1H)-yl]acetamide BDBM50304408 CHEMBL605935
NSC 9152 11,12-dihydroxy-5,10-dioxo-4a,5,10,11,12,12a-hexahydro-1-azatetraphene-11,12-disulfonic acid Cancer Chemotherapy National Service Center (CCNSC) compound 9152 BDBM510
US11267823, Example C-3 5-Hydroxy-6,10-dioxo-3,4,6,9,9a,10-hexahydro-2H-1-oxa-4a,8a-diazaanthracene-7-carboxylic acid 4-fluorobenzylamide BDBM541769
[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-(4-phenoxy-phenyl)-methanol CHEMBL182827 BDBM50153517
[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-(4-trifluoromethyl-phenyl)-methanol BDBM50153510 CHEMBL360248
oxypyrazole, 4a (3R,5S)-6-{[3-(benzylcarbamoyl)-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid BDBM18388
(4aS,6aS,6bR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid oleanolic acid CHEMBL168 (4aS,6aS,6bR,10S,12aR,14bS)-10-Hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-2H-picene-4a-carboxylic acid BDBM50079577
BDBM50246619 (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-benzyl 10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate benzyl (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10- hydroxy-2,2,6a,6b,9,9,12a-heptamethyl- 1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b- tetradecahydropicene-4a-carboxylate (Compound 4) CHEMBL445301
Dihydrohydroxycodeinone hydrochloride SMR001338853 Oxycodone hydrochloride (4R,4aS,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride cid_5464086 (4R,4aS,12bS)-9-methoxy-3-methyl-4a-oxidanyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride BDBM83451 MLS002320707
cid_53383840 ethyl (3S,4aS)-1-[2-(cyclohexen-1-yl)ethyl]-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylate SMR002354080 (3S,4aS)-1-[2-(cyclohexen-1-yl)ethyl]-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylic acid ethyl ester (3S,4aS)-1-[2-(1-cyclohexenyl)ethyl]-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylic acid ethyl ester ethyl (3S,4aS)-1-[2-(cyclohexen-1-yl)ethyl]-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-2-oxidanylidene-4,5,6,7-tetrahydro-3H-quinoline-4a-carboxylate MLS003674784 BDBM96853
ethyl (3S,4aS)-1-[2-(cyclohexen-1-yl)ethyl]-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-2-oxidanylidene-3,4,5,6-tetrahydrocyclopenta[b]pyridine-4a-carboxylate MLS003551950 SMR002202695 (3S,4aS)-1-[2-(cyclohexen-1-yl)ethyl]-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-3,4,5,6-tetrahydro-1-pyrindine-4a-carboxylic acid ethyl ester cid_53300065 ethyl (3S,4aS)-1-[2-(cyclohexen-1-yl)ethyl]-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-3,4,5,6-tetrahydrocyclopenta[b]pyridine-4a-carboxylate (3S,4aS)-1-[2-(1-cyclohexenyl)ethyl]-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-2-oxo-3,4,5,6-tetrahydrocyclopenta[b]pyridine-4a-carboxylic acid ethyl ester BDBM96845
((1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-carbamic acid chloromethyl ester CHEMBL253945 BDBM50233006
(4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (1-adamantan-1-yl-ethyl)-amide BDBM50172206 CHEMBL371990
(4aS,6aS,6bR,12aR,14bS)-benzyl 2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate BDBM50184599 CHEMBL210763
(R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-thiophen-2-yl-methanol BDBM50165105 CHEMBL196347
1-((1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-3-isobutyl-thiourea CHEMBL439415 BDBM50233028
1-(4-fluorophenyl)-4a-methyl-4'-phenyl-(4'S,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] BDBM50167819 CHEMBL365821
1-(4-fluorophenyl)-4a-methyl-4'-phenyl-(4'S,4aS,5'S)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] CHEMBL194114 BDBM50167791
1-(4-fluorophenyl)-4a-methyl-4'-vinyl-(4'S,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] CHEMBL194059 BDBM50167807
1-(4-fluorophenyl)-4a-methyl-4'-vinyl-(4'S,4aS,5'S)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] CHEMBL364031 BDBM50167814
1-[(2R)-4-(6-acetamido-1H-indol-1-yl)-1-hydroxybutan-2-yl]-1H-imidazole-4-carboxamide Hybrid compound 1(FR235999) derivative, 4a BDBM22927
2,2,2-trifluoro-N-((1S,13bR)-6-vinyl-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-acetamide CHEMBL252647 BDBM50233029
4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid methyl ester BDBM50025344 CHEMBL574911
BDBM20985 4-{8-[butyl(ethyl)amino]-6-methyl-2-oxo-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-4-yl}-3-methylbenzonitrile Pyridopyrazinone, 4a
BDBM231686 3-(4-(4,5-Diphenyl-1-propyl-1H-imidazol-2-yl)-1-phenyl-1Hpyrazol- 3-yl)-4a,8a-dihydro-2H-chromen-2-one (3e)
BDBM327955 (4a-S,9a-R)-1-(1H-Benzoimidazole-5-carbonyl)-5-methyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine-6-carbonitrile US9663470, 177
BDBM395251 US10308629, Example 13 (4aR,5aR or 4aS,5aS)-3-(Phenylamino)-2-(pyridin-4-yl)-4a,5,5a,6-tetrahydrocyclopropa[f]indol-4(1H)-one
BDBM395252 US10308629, Example 14 (4aS,5aS or 4aR,5aR)-3-(Phenylamino)-2-(pyridin-4-yl)-4a,5,5a,6-tetrahydrocyclopropa[f]indol-4(1H)-one
BDBM395254 rel-(4aR,5aR)-5a-Methyl-3-(phenylamino)-2-(pyridin-4-yl)-4a,5,5a,6-tetrahydrocyclopropa[f]indol-4(1H)-one US10308629, Example 16
BDBM50032795 (4aR,6aS)-7-(Indole-1-carbonyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one CHEMBL321867
BDBM50165101 CHEMBL365818 (R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-pyridin-4-yl-methanol
BDBM50165432 (4aS,6aS,6bR,12aR)-2,2,6a,6b,9,9,12a-Heptamethyl-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,12a,12b,13,14b-hexadecahydro-2H-picene-4a-carboxylic acid CHEMBL196236
BDBM50167795 1-(4-fluorophenyl)-4',4a,5'-trimethyl-(4'R,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] CHEMBL194012
BDBM50167798 1-(4-fluorophenyl)-4a-methyl-4'-vinyl-(4'R,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] CHEMBL194013
BDBM50167812 1-(4-fluorophenyl)-4a-methyl-4'-phenyl-(4'R,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] CHEMBL196232
BDBM50233012 N-((1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-thia-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide CHEMBL252449
BDBM50233013 N-((1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamidine CHEMBL253944
BDBM50233016 N-((1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-thioacetamide CHEMBL253735
BDBM50233022 CHEMBL252450 2,2,2-trifluoro-N-((1S,13bR)-6-fluoro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-acetamide
BDBM50246736 (4aS,6aS,6bR,8aS,12aS,12bR,14bS)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid CHEMBL472896
BDBM596310 US11591336, Compound 514 (1-(3-((4a,8a- dihydroisoquinolin- 6-yl)thio)-1H- pyrazolo[3,4- b]pyrazin-6-yl)-4- methylpiperidin-4- yl)methanamine
Benzofuran Pyridine Derivative 4a 6-Methoxybenzofuran-2-yl-(4-fluorophenyl)-3-pyridylmethanol (4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)pyridin-3-ylmethanol BDBM10000
CHEMBL193704 BDBM50167813 1-(4-fluorophenyl)-4a-methyl-4'-vinyl-(4'R,4aS,5'S)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)]
CHEMBL195524 1-(4-fluorophenyl)-4a-methyl-4'-phenyl-(4'R,4aS,5'S)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] BDBM50167802
CHEMBL252253 BDBM50233010 N-((1R,13bS)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide
CHEMBL252451 BDBM50233020 N-((1S,13bR)-6,7-dichloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide
CHEMBL252850 N-((1S,13bR)-5-acetyl-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide BDBM50233017
CHEMBL327365 BDBM50146292 Biphenyl-2-carboxylic acid [4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide
CHEMBL3349157 BDBM50025422 Sodium; 2-(4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinolin-7-yl)-propionate
CHEMBL338207 BDBM50037932 (4aR,6aR)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one
CHEMBL338707 (4aR,6aR)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-indeno[5,4-f]quinolin-2-one BDBM50037914
CHEMBL371376 BDBM50165103 (R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-furan-3-yl-methanol
CHEMBL402527 BDBM50233008 2,2,2-trifluoro-N-((1S,13bR)-5-vinyl-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-acetamide
CHEMBL403138 BDBM50233026 N-((1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide
CHEMBL404432 BDBM50233023 N-((1S,13bR)-6-chloro-9-methyl-1,2,3,4,9,13b-hexahydro-4a,9-diaza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide
CHEMBL404433 N-((1S,13bR)-5,6-dichloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide BDBM50233025
CHEMBL77067 1,2,4-Oxadiazole Analogue 4a BDBM5092 4-[(2S)-2-{[(1S)-1-(3-benzyl-1,2,4-oxadiazol-5-yl)-3-carbamoylpropyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid
N-((1S,13bR)-5-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide CHEMBL402526 BDBM50233019
N-((1S,13bR)-7-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide BDBM50233015 CHEMBL252646
US9663470, 175 BDBM327953 (4a-S,9a-R)-1-(1H-Benzoimidazole-5-carbonyl)-7-methyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine-6-carbonitrile
US9663470, 176 BDBM327954 (4a-R,9a-S)-1-(1H-Benzoimidazole-5-carbonyl)-5-methyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine-6-carbonitrile
((3aS,4aS,7aS,7bR)-6,6-Dimethyl-3a,4a,7a,7b-tetrahydro-[1,3]dioxolo[4',5':4,5]furo[2,3-d]isoxazol-3-yl)-methanol BDBM50073992 CHEMBL93319
(2-Benzyloxy-ethyl)-[2-((4aS,10aR)-6-methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-amine; compound with GENERIC INORGANIC NEUTRAL COMPONENT BDBM50142864 CHEMBL545669
(2-Methoxy-ethyl)-[2-((4aS,10aR)-6-methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-amine; compound with GENERIC INORGANIC NEUTRAL COMPONENT CHEMBL542368 BDBM50142866
(4aR,6aR,7R)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-indeno[5,4-f]quinolin-2-one BDBM50057503 CHEMBL283508
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid phenylamide BDBM50032778 CHEMBL324210
(4aR,8aR)-7-Ethyl-4a-(3-hydroxy-phenyl)-3-methyl-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrrolo[3,2-g]isoquinoline-2-carbothioic acid diethylamide BDBM50290869 CHEMBL101516
(4aS,6aS,6bR,12aR,14bS,E)-benzyl 10-(hydroxyimino)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate BDBM50184605 CHEMBL207108
(6S,9R,14R,16aS)-9-[(Adamantane-1-carbonyl)-amino]-6-carboxymethyl-8,16-dioxo-tetradecahydro-11,12-dithia-4a,7,15-triaza-benzocyclotetradecene-14-carboxylic acid BDBM50089000 CHEMBL178796
(cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propylamino)pentyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one BDBM50304390 CHEMBL596185
1-(4-fluorophenyl)-4a-methyl-4',5'-diphenyl-(4'R,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] BDBM50167788 CHEMBL195990
1-Amino-4a,6a-dimethyl-2-oxo-2,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid diethylamide BDBM50025380 CHEMBL3349510
4',5'-diethyl-1-(4-fluorophenyl)-4a-methyl-(4'R,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] CHEMBL370194 BDBM50167806
6-Methyl-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-4a,5,6,7,8,8a-hexahydro-3H-pyrido[4,3-d]pyrimidin-4-one BDBM50171735 CHEMBL198422
9-fluoro-5-(1H-pyrrol-2-yl)-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(11),4,6,8(12),9-pentaen-3-one trisubstituted naphthostyril analogue 4a BDBM10135
BDBM18878 N-acylated-alpha-amino acid derivative, 4a (2S)-2-(1-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy]phenyl}acetamido)butanedioic acid
BDBM50025373 1-Hydroxy-4a,6a-dimethyl-2-oxo-2,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid diethylamide CHEMBL3349512
BDBM50057492 (4aR,6aS,7S)-7-(Indole-1-carbonyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one CHEMBL24465
BDBM50165436 (4aS,6aR,6bR,12aR)-2,2,6a,6b,9,9,12a-Heptamethyl-10,14-dioxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,12a,12b,13,14,14a,14b-octadecahydro-2H-picene-4a-carboxylic acid CHEMBL194396
BDBM50167796 CHEMBL195723 1-(4-fluorophenyl)-4a-methyl-4',5'-divinyl-(4'R,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)]
BDBM50167815 1-(4-fluorophenyl)-4',4',4a,6'-tetramethyl-(4aS,6'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro-4'H-[1,3]dioxane)] CHEMBL195654
BDBM50172191 3-[((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amino]-adamantane-1-carboxylic acid ethyl ester CHEMBL196335
BDBM50184616 (4aS,6aS,6bR,12aR,14bS,E)-10-(hydroxyimino)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid CHEMBL379848
BDBM50184617 CHEMBL383274 (4aS,6aS,6bR,10S,12aR,14bS)-benzyl 10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate
Biphenyl-2-carboxylic acid [4-((R)-3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide CHEMBL96731 BDBM50146286
Biphenyl-2-carboxylic acid [4-((S)-3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide CHEMBL329903 BDBM50146285
CHEMBL186805 1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-3-phenyl-propan-1-ol BDBM50153513
CHEMBL193986 BDBM50167800 1-(4-fluorophenyl)-4',4a-dimethyl-(4'S,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro-4'H-[1,3]dioxane)]
CHEMBL195967 BDBM50167810 1-(4-fluorophenyl)-4',4',4a,6'-tetramethyl-(4aS,6'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro-4'H-[1,3]dioxane)]
CHEMBL321442 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid diphenylamide BDBM50032769
CHEMBL336746 BDBM50053908 4-Cyano-N-{3-[1-(4-hydroxy-2-oxo-4a,5,6,7,8,9,10,10a-octahydro-2H-cycloocta[b]pyran-3-yl)-2,2-dimethyl-propyl]-phenyl}-benzenesulfonamide
CHEMBL363760 BDBM50153508 Benzo[b]thiophen-3-yl-[(4aR,5S)-1-(4-fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-methanol
CHEMBL380790 BDBM50167816 1-(4-fluorophenyl)-4',4a-dimethyl-(4'R,4aS,5'S)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro-4'H-[1,3]dioxane)]
CHEMBL596175 (cis)-4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propylamino)pentyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one BDBM50304389
CHEMBL93861 BDBM50146310 Biphenyl-2-carboxylic acid [4-((S)-3,4,11,11a-tetrahydro-1H,5H-2-oxa-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide
Compound 2529-0078 1-(10,10a-dihydro-4aH-phenothiazin-10-yl)-2-aminoethan-1-one BDBM25813 2-(4a,10a-dihydro-10H-phenothiazin-10-yl)-2-oxoethanamine
MLS001333136 SMR000875274 sodium;(4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-oxidanidyl-2-oxidanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol Adenosine 3',5'-cyclic monophosphate sodium salt monohydrate sodium;(4aR,6R,7R,7aS)-6-adenin-9-yl-2-keto-2-oxido-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-ol cid_23669773 sodium;(4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol BDBM81289 sodium;(4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-ol
sodium;[(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxidanidyl-2-oxidanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate;hydrate sodium;butanoic acid [(4aR,6R,7R,7aR)-2-oxido-2-oxo-6-[6-(1-oxobutylamino)-9-purinyl]-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-yl] ester;hydrate BDBM81293 cid_23666343 SMR001562129 sodium;butyric acid [(4aR,6R,7R,7aR)-6-(6-butyramidopurin-9-yl)-2-keto-2-oxido-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-yl] ester;hydrate sodium;[(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate;hydrate MLS002695977
(2E,4S,4aS,5aS,6S,12aS)-2-[azanyl(oxidanyl)methylidene]-7-chloranyl-4-(dimethylamino)-6,10,11,12a-tetrakis(oxidanyl)-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride 7-CHLORO-6-DEMETHYLTETRACYCLINE HYDROCHLORIDE SMR000058439 MLS000028422 (2E,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride BDBM37533 cid_6602612 (2E,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride
(2Z,4S,5S,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;ethanol;hydrate;hydrochloride MLS001332531 SMR000875231 (2Z,4S,5S,6R,12aS)-2-[amino(hydroxy)methylene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;ethanol;hydrate;hydrochloride cid_24981347 (2Z,4S,5S,6R,12aS)-2-[azanyl(oxidanyl)methylidene]-4-(dimethylamino)-6-methyl-5,10,11,12a-tetrakis(oxidanyl)-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;ethanol;hydrate;hydrochloride BDBM53381 Doxycycline hyclate
(4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-one;iodide Naloxone methiodide (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-methyl-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-one;iodide MLS001334009 SMR000875254 cid_16219719 (4R,4aS,7aR,12bS)-3-methyl-4a,9-bis(oxidanyl)-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-one;iodide BDBM83098
(1R,2R,4aR,5R,7S,8aR)-7-acetoxy-5-(methoxycarbonyl)-4a-methyl-8-oxo-1-(2-(tetrahydrofuran-3-yl)ethyl)-decahydronaphthalene-2-carboxylic acid CHEMBL226677 BDBM50216135
(4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (6,6-dimethyl-bicyclo[3.1.1]hept-2-yl)-amide BDBM50172197 CHEMBL197522
(4aR,5aR or 4aS,5aS)-5a-Methyl-3-(phenylamino)-2-(pyridin-4-yl)-4a,5,5a,6-tetrahydrocyclopropa[f]indol-4(1H)-one US10308629, Example 17 BDBM395255
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid m-tolylamide BDBM50032783 CHEMBL108151
(4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid diphenylamide CHEMBL24191 BDBM50057490
(4aS,6aS,6bR,10S,12aR,14bS)-10-(3-carboxypropanoyloxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid BDBM50184602 CHEMBL210886
(4aS,6aS,6bR,12aS)-11-Cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,13-dioxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,12a,12b,13,14b-hexadecahydro-2H-picene-4a-carboxylic acid BDBM50165429 CHEMBL196027
(4aS,6aS,6bR,13aR,15bS)-2,2,6a,6b,9,9,13a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,13,13a,13b,14,15b-octadecahydropiceno[2,3-c][1,2,5]oxadiazole-4a-carboxylic acid BDBM50184601 CHEMBL381802
(4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxamide BDBM50246584 CHEMBL461344
(4aS,6aS,6bR,8aR,12aS,12bR,14bS)-2,2,6a,6b,9,9,12a-heptamethyl-10-methylene-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid CHEMBL489670 BDBM50246746
(S)-2-(cyclopropyl((2,6-diamino-5-cyanopyrimidin-4-yl)amino)methyl)-3-(3-difluoromethyl)-5-fluorophenyl-4-oxo-3,4-dihydroquinazoline-5-carbonitrile US9765060, Compound 4a BDBM341174
(rac)-N-(3-(6-hydroxy-4a-methyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide BDBM410261 US10377770, Example 26
(rac)-N-(3-(6-hydroxy-4a-methyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide BDBM410262 US10377770, Example 27
1-(4-fluorophenyl)-4',4a,5'-trimethyl-(4'R,4aS,5'R)-spiro[4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazole-5,2'-(dihydro[1,3]dioxolane)] CHEMBL371988 BDBM50167818
1-(4-fluorophenyl)-4',4a,6'-trimethyl-(4'R,4aS,6'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro-4'H-[1,3]dioxane)] BDBM50167804 CHEMBL365546
1-(4-fluorophenyl)-4',5'-di(methoxymethyl)-4a-methyl-(4'R,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)] BDBM50167787 CHEMBL193703
3-(4-(1-(3,5-Dimethylphenyl)-4,5-diphenyl-1H-imidazol-2-yl)- 1-phenyl-1H-pyrazol-3-yl)-4a,8a-dihydro-2H-chromen-2-one (3d) BDBM231685
3-(4-(1-(4-Bromophenyl)-4,5-diphenyl-1H-imidazol-2-yl)-1- phenyl-1H-pyrazol-3-yl)-4a,8a-dihydro-2H-chromen-2-one (3b) BDBM231683
3-(4-(1-(4-Chlorophenyl)-4,5-diphenyl-1H-imidazol-2-yl)-1- phenyl-1H-pyrazol-3-yl)-4a,8a-dihydro-2H-chromen-2-one (3a) BDBM231682
3-(4-(1-(4-Methoxyphenyl)-4,5-diphenyl-1H-imidazol-2-yl)-1- phenyl-1H-pyrazol-3-yl)-4a,8a-dihydro-2H-chromen-2-one (3c) BDBM231684
4a,12a-dihydroxy-9-(4-methoxyphenyl)-4,4,6a,12b-tetramethyl-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H,11H-benzo[f]pyrano[4,3-b]chromene-3,11-dione CHEMBL183813 BDBM50157914
BDBM231688 6-Bromo-3-(4-(1-(3,5-dimethylphenyl)-4,5-diphenyl-1Himidazol- 2-yl)-1-phenyl-1H-pyrazol-3-yl)-4a,8a-dihydro-2Hchromen- 2-one (3g)
BDBM50032773 CHEMBL322592 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid p-tolylamide
BDBM50037916 CHEMBL338376 (4aR,6aR,10R)-7-(1,5-Dimethyl-hexyl)-4a,6a,10-trimethyl-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-indeno[5,4-f]quinolin-2-one
BDBM50057507 (4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid phenylamide CHEMBL25664
BDBM50146291 Biphenyl-2-carboxylic acid [3-hydroxy-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide CHEMBL328791
BDBM50146300 Biphenyl-2-carboxylic acid [4-(2,2-dioxo-1,2,3,4,11,11a-hexahydro-5H-2lambda*6*-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide CHEMBL96255
BDBM50146305 CHEMBL93366 Biphenyl-2-carboxylic acid [4-(8-methyl-3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide
BDBM50146307 Biphenyl-2-carboxylic acid [4-(9-chloro-3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide CHEMBL93195
BDBM50146308 Biphenyl-2-carboxylic acid [3-methoxy-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide CHEMBL93209
BDBM50165100 CHEMBL194077 (R)-(2,5-Dichloro-thiophen-3-yl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-methanol
BDBM50165102 (S)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-(6-fluoro-pyridin-3-yl)-methanol CHEMBL364015
BDBM50165104 CHEMBL362914 (R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-(6-fluoro-pyridin-3-yl)-methanol
BDBM50165431 (4aS,6aS,6bR,12aR)-11-Cyano-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,12a,12b,13,14b-hexadecahydro-2H-picene-4a-carboxylic acid CHEMBL195352
BDBM50290866 (4aR,8aR)-7-Ethyl-4a-(3-hydroxy-phenyl)-3-methyl-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrrolo[3,2-g]isoquinoline-2-carboxylic acid ethyl ester CHEMBL322181
BDBM528345 US11180503, Example 4a 9-([1,1'-bi(cyclopropan)]-1-yl)-5-(2-methoxybutyl)pyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrazin-6(5H)-one (isomer 1)
BDBM7678 Imidazo[1,2-b]pyridazine deriv. 4a N-(2-methoxyethyl)-4-[(4-{6-methoxyimidazo[1,2-a]pyridazin-3-yl}pyrimidin-2-yl)amino]benzene-1-sulfonamide
Biphenyl-2-carboxylic acid [3-chloro-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide BDBM50146288 CHEMBL90657
CHEMBL107565 BDBM50032767 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid o-tolylamide
CHEMBL1078407 (4aS,6aS,6bR,8aS,12aS,12bR,14bS)-benzyl 2,2,6a,6b,9,9,12a-heptamethyl-11-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate BDBM50310509
CHEMBL126686 (4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-4a,6a,10-trimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one BDBM50037925
CHEMBL193404 BDBM50165106 (R)-(5-Chloro-thiophen-2-yl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]-methanol
CHEMBL3349089 BDBM50025441 2-(4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinolin-7-yl)-propionic acid methyl ester
CHEMBL3349162 BDBM50025392 4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (1,1,3,3-tetramethyl-butyl)-amide
CHEMBL362988 1-(4-fluorophenyl)-4',4a,6'-trimethyl-(4'R,4aS,6'S)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro-4'H-[1,3]dioxane)] BDBM50167792
CHEMBL423868 Biphenyl-2-carboxylic acid [3-methyl-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide BDBM50146294
CHEMBL424984 4a,12a-dihydroxy-9-(4-methoxyphenyl)-4,4,6a,12b-tetramethyl-3,4a,5,6,6a,12,12a,12b-octahydro-4H,11H-benzo[f]pyrano[4,3-b]chromene-3,11-dione BDBM50157915
CHEMBL434183 1-(4-fluorophenyl)-4',4a,6'-trimethyl-(4'S,4aS,6'S)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro-4'H-[1,3]dioxane)] BDBM50167790
CHEMBL92187 BDBM50146298 Biphenyl-2-carboxylic acid [4-(8,9-difluoro-3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide
CHEMBL92470 BDBM50146295 Biphenyl-2-carboxylic acid [4-(8-fluoro-3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide
CHEMBL93205 BDBM50146312 Biphenyl-2-carboxylic acid [3-fluoro-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide
N-((1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-N-methyl-acetamide CHEMBL401627 BDBM50233018
US10308629, Example 18 BDBM395256 (4aS,5aS or 4aR,5aR)-5a-Methyl-3-(phenylamino)-2-(pyridin-4-yl)-4a,5,5a,6-tetrahydrocyclopropa[f]indol-4(1H)-one
[1-(2-Benzyl-octahydro-4a(S)-pyrido[1,2-c]pyrimidin-5(R)-ylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester BDBM50106592 CHEMBL133539
BDBM50165430 (4aS,6aS,6bR,12aR)-2,2,6a,6b,9,9,12a-Heptamethyl-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-2H-picene-4a-carboxylic acid CHEMBL470029 (4aS,6aS,6bR,8aR,12aR,12bR,14bS)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid oleanonic acid 3-Oxoolean-12-en-28-oic Acid
US20240208984, Compound Naltrexone SMR000058767 US9107954, naltrexone BDBM60212 cid_5485201 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride NALTREXONE HYDROCHLORIDE US10988481, Compound NTX (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride MLS000069607
methyl (4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate BDBM50175875 Maslinic acid methyl ester (4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-methyl 10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate CHEMBL202346
BDBM52947 Doxycycline Doxycycline hyclate cid_16746590 (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;ethanol;hydrate;hydrochloride (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;ethanol;hydrate;hydrochloride SMR000326704 (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[azanyl(oxidanyl)methylidene]-4-(dimethylamino)-6-methyl-5,10,11,12a-tetrakis(oxidanyl)-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;ethanol;hydrate;hydrochloride MLS001056533
(3S,4aR,4bS,8R,8aR,10aR)-3-Furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-6,8-dicarboxylic acid 8-methyl ester CHEMBL1257489 BDBM50327511
(3S,4aR,6R,8R,8aR)-6-Dimethylamino-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester CHEMBL196039 BDBM50166719
(3S,4aR,6R,8R,8aR)-6-Ethylamino-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester BDBM50166716 CHEMBL197572
(3S,4aR,6S,8R,8aR)-3-Furan-3-yl-4a,8a-dimethyl-1,5-dioxo-6-propoxy-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester CHEMBL196670 BDBM50166718
(3S,4aR,6S,8R,8aR)-3-Furan-3-yl-6-hydroxy-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester BDBM50166720 CHEMBL194982
(3S,4aR,6S,8R,8aR)-6-Acetoxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester CHEMBL193735 BDBM50166728
(3S,4aR,6S,8R,8aR)-6-Allyloxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester BDBM50166733 CHEMBL194619
(3S,4aR,6S,8R,8aR)-6-Benzyloxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester CHEMBL381244 BDBM50166725
(3S,4aR,6S,8R,8aR)-6-Butyryloxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester BDBM50166724 CHEMBL196099
(3S,4aR,6S,8R,8aR)-6-Ethylcarbamoyloxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester BDBM50166734 CHEMBL195627
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid biphenyl-4-ylamide BDBM50032779 CHEMBL109089
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid ethyl-phenyl-amide BDBM50032761 CHEMBL321923
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid methyl-phenyl-amide BDBM50032764 CHEMBL111407
(4aR,6aS)-7-(3,4-Dihydro-2H-quinoline-1-carbonyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one CHEMBL327098 BDBM50032798
(4aS,6aS,6bR,12aR,14bS,E)-11-(hydroxyimino)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid BDBM50184614 CHEMBL209125
(4aS,6aS,6bR,8aR,13aR,13bR,15bS)-2,2,6a,6b,9,9,13a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,13,13a,13b,14,15b-octadecahydropiceno[2,3-d]isoxazole-4a-carboxylic acid BDBM50299740 CHEMBL582862
(4aS,6aS,6bR,8aR,14aR,14bR,16bS)-2,2,6a,6b,9,9,14a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,14,14a,14b,15,16b-octadecahydrochryseno[1,2-g]quinazoline-4a-carboxylic acid BDBM50299739 CHEMBL576164
1-(4-((4-Chloro-2-methoxy-3-((tetrahydro-2H-pyran-4-yl)methyl)quinolin-6-yl)(hydroxy)(phenyl)methyl)piperidin-1-yl)ethanone US10201546, Example 4a BDBM339030
1-(4-fluorophenyl)-4a-methyl-4',5'-dipropyl-(4'R,4aS,5'R)-spiro[4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazole-5,2'-(dihydro[1,3]dioxolane)] BDBM50167789 CHEMBL193760
4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carbothioic acid S-pyridin-2-yl ester CHEMBL3349096 BDBM50025387
BDBM19216 cyclopenta[f]indazole, 9 (S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H-cyclopenta[f]indazol-5-yl](4-fluorophenyl)methanol
BDBM3680 4-anilinopyrimido[5,4-d]pyrimidine deriv. 4a 6-Chloro-4-(phenylamino)pyrimido[5,4-d]pyrimidine 6-chloro-N-phenyl-[1,3]diazino[5,4-d]pyrimidin-4-amine
BDBM50032765 CHEMBL322749 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid biphenyl-3-ylamide
BDBM50032786 CHEMBL107719 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid naphthalen-2-ylamide
BDBM50033235 7-[4-(2-Methyl-imidazo[4,5-c]pyridin-1-yl)-phenyl]-1-phenyl-3,4-dihydro-6H-2,2a,4a,8-tetraaza-cyclopenta[cd]azulen-5-one CHEMBL331124
BDBM50037924 CHEMBL124750 (4aR,6aR,10R)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-10-propyl-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-indeno[5,4-f]quinolin-2-one
BDBM50146290 CHEMBL330494 N-[3-Chloro-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-5-fluoro-2-methyl-benzamide
BDBM50166730 CHEMBL363825 (3S,4aR,6S,8R,8aR)-3-Furan-3-yl-4a,8a-dimethyl-6-methylcarbamoyloxy-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
BDBM50167797 4',5'-diethyl-1-(4-fluorophenyl)-4a-methyl-(4'R,4aS,5'R)-spiro[4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazole-5,2'-(dihydro[1,3]dioxolane)] CHEMBL197312
BDBM50184600 (4aS,6aS,6bR,13aR,15bS)-benzyl 2,2,6a,6b,9,9,13a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,9a,12a,13,13a,13b,14,15b-icosahydropiceno[2,3-d]isoxazole-4a-carboxylate CHEMBL208852
BDBM50184604 (4aS,6aS,6bR,10Z,11E,12aR,14bS)-benzyl 10,11-bis(hydroxyimino)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate CHEMBL379852
BDBM50246597 (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-hydroxy-N,2,2,6a,6b,9,9,12a-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxamide CHEMBL461165
BDBM50246738 CHEMBL449967 (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(carboxycarbonyloxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
BDBM50310517 (4aS,6aS,6bR,8aS,11R,12aS,12bR,14bS)-benzyl 11-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate CHEMBL1077661
BDBM50327505 (3S,4aR,4bS,8R,8aR,10aR)-3-Furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxyli c acid methyl ester CHEMBL1257853
BDBM7664 Imidazo[1,2-a]pyridine deriv. 4a 4-[(5-chloro-4-{imidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)amino]-N-(2-methoxyethyl)benzene-1-sulfonamide
BMC175834 Compound 4a (3S,6S,7R,9aS)-6-[(2S)-2-aminobutanamido]-7-(aminomethyl)-N-(diphenylmethyl)-5-oxo-octahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide Smac010 BDBM26204
CHEMBL107654 BDBM50032785 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid naphthalen-1-ylamide
CHEMBL111142 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid biphenyl-2-ylamide BDBM50032790
CHEMBL1796869 BDBM50346679 benzyl (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-[(2- chloroacetyl)oxy]-2,2,6a,6b,9,9,12a-heptamethyl- 1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b- tetradecahydropicene-4a-carboxylate (Compound 5)
CHEMBL1796870 BDBM50346680 benzyl (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-[(2- azidoacetyl)oxy]-2,2,6a,6b,9,9,12a-heptamethyl- 1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b- tetradecahydropicene-4a-carboxylate (Compound 6)
CHEMBL193787 BDBM50166723 (3S,4aR,6S,8R,8aR)-6-Ethoxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
CHEMBL193798 1-(4-fluorophenyl)-4a-methyl-4',5'-diphenyl-(4'R,4aS,5'R)-spiro[4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazole-5,2'-(dihydro[1,3]dioxolane)] BDBM50167817
CHEMBL195589 (3S,4aR,6R,8R,8aR)-3-Furan-3-yl-4a,8a-dimethyl-6-methylamino-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester BDBM50166717
CHEMBL196789 (3S,4aR,6S,8R,8aR)-3-Furan-3-yl-4a,8a-dimethyl-1,5-dioxo-6-propionyloxy-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester BDBM50166729
CHEMBL196975 BDBM50167805 4',5'-dibutyl-1-(4-fluorophenyl)-4a-methyl-(4'R,4aS,5'R)-spiro[4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazole-5,2'-(dihydro[1,3]dioxolane)]
CHEMBL208693 (4aS,6aS,6bR,12aR,14bS,E)-benzyl 11-(hydroxymethylene)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate BDBM50184619
CHEMBL208753 BDBM50184608 2-((4aS,6aS,6bR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carbonyloxy)acetic acid
CHEMBL209010 (4aS,6aS,6bR,10S,12aR,14bS)-2-(methylamino)ethyl 10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate BDBM50184607
CHEMBL211013 (4aS,6aS,6bR,13aR,15bS)-2,2,6a,6b,9,9,13a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,9a,12a,13,13a,13b,14,15b-icosahydropiceno[2,3-d]isoxazole-4a-carboxylic acid BDBM50184618
CHEMBL332781 (4aR,6aR,10R)-7-(1,5-Dimethyl-hexyl)-10-ethyl-4a,6a-dimethyl-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-indeno[5,4-f]quinolin-2-one BDBM50037918
CHEMBL371079 BDBM50166715 (3S,4aR,6S,8R,8aR)-6-Carbamoyloxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
CHEMBL380025 BDBM50184610 (4aS,6aS,6bR,12aR,14bS,E)-benzyl 11-(benzyloxyimino)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate
CHEMBL380084 (4aS,6aS,6bR,12aR,14bS,E)-benzyl 11-(hydroxyimino)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate BDBM50184598
CHEMBL382102 BDBM50167799 1-(4-fluorophenyl)-4a-methyl-4',5'-divinyl-(4'R,4aS,5'R)-spiro[4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazole-5,2'-(dihydro[1,3]dioxolane)]
CHEMBL383555 BDBM50166727 (3S,4aR,6S,8R,8aR)-6-Butoxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
CHEMBL414428 (4aR,6aR,10R)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-10-phenyl-1,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-indeno[5,4-f]quinolin-2-one BDBM50037919
CHEMBL426097 BDBM50166721 (3S,4aR,6S,8R,8aR)-3-Furan-3-yl-6-methoxy-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
CHEMBL448816 BDBM50246741 (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(benzyloxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
CHEMBL541940 BDBM50299738 (4aS,6aS,6bR,8aR,16aR,16bR,18bS)-2,2,6a,6b,9,9,16a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,16,16a,16b,17,18b-octadecahydrochryseno[2,1-b]phenazine-4a-carboxylic acid
CHEMBL562059 (4aS,6aS,6bR,8aR,14aR,14bR,16bS)-2,2,6a,6b,9,9,14a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,14,14a,14b,15,16b-octadecahydrochryseno[2,1-g]quinoxaline-4a-carboxylic acid BDBM50299737
CHEMBL575688 BDBM50299735 (4aS,6aS,6bR,8aR,14aR,14bR,16bS)-2,2,6a,6b,9,9,11,14a-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,14,14a,14b,15,16b-octadecahydrochryseno[1,2-g]quinazoline-4a-carboxylic acid
[(1R,2S,4R)-4-{[5-({4-[(R)-(3-chlorophenyl)(hydroxy)methyl]-2- thienyl}carbonyl)pyrimidin-4-yl]amino}-2-hydroxycyclopentyl]methyl sulfamate BDBM462454 US10780090, Compound I-4a
cyclopenta[f]indazole, 8 BDBM19215 (R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H-cyclopenta[f]indazol-5-yl](4-fluorophenyl)methanol
(3R,4aR,5R,7R)-7-tert-butyl-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-5-methyl-1-octyl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester cid_56589305 MLS003812928 (3R,4aR,5R,7R)-7-tert-butyl-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-5-methyl-1-octyl-2-oxo-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester SMR002481883 methyl (3R,4aR,5R,7R)-7-tert-butyl-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-5-methyl-1-octyl-2-oxidanylidene-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate BDBM96893 methyl (3R,4aR,5R,7R)-7-tert-butyl-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-5-methyl-1-octyl-2-oxo-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate
(3R,4aR,5R,7S)-5-cyclopropyl-1-octyl-2-oxo-3-[2-oxo-2-(prop-2-ynylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester cid_60156978 SMR002530922 MLS003874257 (3R,4aR,5R,7S)-5-cyclopropyl-7-isopropyl-2-keto-3-[2-keto-2-(propargylamino)ethyl]-1-octyl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester methyl (3R,4aR,5R,7S)-5-cyclopropyl-1-octyl-2-oxidanylidene-3-[2-oxidanylidene-2-(prop-2-ynylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate BDBM115111 methyl (3R,4aR,5R,7S)-5-cyclopropyl-1-octyl-2-oxo-3-[2-oxo-2-(prop-2-ynylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate
BDBM113987 MLS003874263 SMR002530928 (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-[(3,4-dimethoxyphenyl)methylamino]-2-oxoethyl]-1-octyl-2-oxo-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester (3R,4aR,5R,7S)-5-cyclopropyl-7-isopropyl-2-keto-3-[2-keto-2-(veratrylamino)ethyl]-1-octyl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester methyl (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-[(3,4-dimethoxyphenyl)methylamino]-2-oxoethyl]-1-octyl-2-oxo-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate methyl (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-[(3,4-dimethoxyphenyl)methylamino]-2-oxidanylidene-ethyl]-1-octyl-2-oxidanylidene-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate cid_60156984
BDBM66980 sodium;[(4aS,5R,6R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxidanidyl-2-oxidanylidene-4a,5,6,7a-tetrahydro-4H-furo[2,3-d][1,3,2]dioxaphosphinin-5-yl] butanoate;hydrate cid_24871279 SMR001233340 sodium;[(4aS,5R,6R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxido-2-oxo-4a,5,6,7a-tetrahydro-4H-furo[2,3-d][1,3,2]dioxaphosphinin-5-yl] butanoate;hydrate MLS002154012 sodium;butyric acid [(4aS,5R,6R,7aR)-6-(6-butyramidopurin-9-yl)-2-keto-2-oxido-4a,5,6,7a-tetrahydro-4H-furo[2,3-d][1,3,2]dioxaphosphorin-5-yl] ester;hydrate Bucladesine sodium salt sodium;butanoic acid [(4aS,5R,6R,7aR)-2-oxido-2-oxo-6-[6-(1-oxobutylamino)-9-purinyl]-4a,5,6,7a-tetrahydro-4H-furo[2,3-d][1,3,2]dioxaphosphorin-5-yl] ester;hydrate
SMR002533043 BDBM113988 (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-(isoamylamino)-2-keto-ethyl]-7-isopropyl-2-keto-1-(1-naphthylmethyl)-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester cid_60157266 methyl (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-(3-methylbutylamino)-2-oxoethyl]-1-(naphthalen-1-ylmethyl)-2-oxo-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate MLS003876098 methyl (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-(3-methylbutylamino)-2-oxidanylidene-ethyl]-1-(naphthalen-1-ylmethyl)-2-oxidanylidene-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-(3-methylbutylamino)-2-oxoethyl]-1-(1-naphthalenylmethyl)-2-oxo-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester
cid_23702958 sodium;(4aR,6R,7R,7aS)-6-(6-azanyl-8-bromanyl-purin-9-yl)-2-oxidanidyl-2-oxidanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol sodium;(4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol BDBM81292 sodium;(4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9-purinyl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-ol 8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt sodium;(4aR,6R,7R,7aS)-6-(6-amino-8-bromo-purin-9-yl)-2-keto-2-oxido-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-ol MLS002153216 SMR000326869
cid_56589328 (3R,4aR,5R,7S)-7-cyclopentyl-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-5-methyl-1-octyl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester (3R,4aR,5R,7S)-7-cyclopentyl-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-5-methyl-1-octyl-2-oxo-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester BDBM96894 SMR002481907 MLS003812952 methyl (3R,4aR,5R,7S)-7-cyclopentyl-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-5-methyl-1-octyl-2-oxidanylidene-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate methyl (3R,4aR,5R,7S)-7-cyclopentyl-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-5-methyl-1-octyl-2-oxo-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate
methyl (3R,4aR,5R,7R)-1-benzyl-7-tert-butyl-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-5-methyl-2-oxo-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate SMR002481931 methyl (3R,4aR,5R,7R)-7-tert-butyl-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxidanylidene-ethyl]-5-methyl-2-oxidanylidene-1-(phenylmethyl)-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate (3R,4aR,5R,7R)-7-tert-butyl-3-[2-[2-(2-methoxyphenyl)ethylamino]-2-oxoethyl]-5-methyl-2-oxo-1-(phenylmethyl)-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester MLS003812976 BDBM96895 (3R,4aR,5R,7R)-1-benzyl-7-tert-butyl-2-keto-3-[2-keto-2-[2-(2-methoxyphenyl)ethylamino]ethyl]-5-methyl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester cid_56589351
MLS001148197 BDBM81290 N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT SMR000058940 sodium;[(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxidanidyl-2-oxidanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate sodium;[(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate sodium;butyric acid [(4aR,6R,7R,7aR)-6-(6-butyramidopurin-9-yl)-2-keto-2-oxido-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-yl] ester sodium;butyric acid [(4aR,6R,7R,7aR)-6-(6-butyramidopurin-9-yl)-2-keto-2-oxido-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-yl] ester;hydrate cid_23663967 sodium;butanoic acid [(4aR,6R,7R,7aR)-2-oxido-2-oxo-6-[6-(1-oxobutylamino)-9-purinyl]-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-yl] ester
(1R,4aS,6aS,6bR,8aS,11S,12aS,12bR,14bS)-benzyl 11-hydroxy-1,2,2,6a,6b,9,9,12a-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate CHEMBL1077658 BDBM50310518
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2-benzoyl-phenyl)-amide BDBM50032776 CHEMBL325572
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-amino-phenyl)-amide BDBM50032780 CHEMBL109088
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-chloro-phenyl)-amide CHEMBL108625 BDBM50032789
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (4-trifluoromethyl-phenyl)-amide BDBM50032758 CHEMBL323033
(4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid naphthalen-1-ylamide CHEMBL285599 BDBM50057475
(4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(2-carboxybenzoyloxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid BDBM50246740 CHEMBL502586
(4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(3-carboxybenzyloxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid CHEMBL506556 BDBM50246743
4-Fluoro-biphenyl-2-carboxylic acid [3-chloro-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide CHEMBL421180 BDBM50146299
BDBM22398 WIN 35,065-2 Analogue, 4a RTI-219 2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-5-phenyl-1,3-thiazole
BDBM50032760 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (4-benzoyl-phenyl)-amide CHEMBL110058
BDBM50032763 CHEMBL110398 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-bromo-phenyl)-amide
BDBM50032770 CHEMBL432977 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (4-amino-phenyl)-amide
BDBM50032772 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2,6-dimethyl-phenyl)-amide CHEMBL108181
BDBM50032781 CHEMBL321617 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (4-fluoro-phenyl)-amide
BDBM50032782 CHEMBL432439 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-trifluoromethyl-phenyl)-amide
BDBM50032784 CHEMBL110288 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2-trifluoromethyl-phenyl)-amide
BDBM50032788 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2-hydroxy-phenyl)-amide CHEMBL109232
BDBM50032791 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (4-hydroxy-phenyl)-amide CHEMBL324687
BDBM50032792 CHEMBL108305 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2-methoxy-phenyl)-amide
BDBM50032793 CHEMBL111476 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2-fluoro-phenyl)-amide
BDBM50032796 CHEMBL323031 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-benzoyl-phenyl)-amide
BDBM50057495 1-((4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carbonyl)-1,3-diisopropyl-urea CHEMBL284645
BDBM50146297 CHEMBL330005 5-Fluoro-biphenyl-2-carboxylic acid [3-chloro-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide
BDBM50146302 CHEMBL328079 N-[3-Chloro-4-((S)-3,4,11,11a-tetrahydro-1H,5H-2-oxa-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-5-fluoro-2-methyl-benzamide
BDBM50169775 CHEMBL178129 (3S,4aR,6S,8R,8aR,10aR)-3-Furan-3-yl-6-hydroxy-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
BDBM50169776 CHEMBL178275 (3S,4aS,8aR,10aR)-3-Furan-3-yl-4a,8a-dimethyl-1,6-dioxo-3,4,4a,6,8a,9,10,10a-octahydro-1H-2-oxa-phenanthrene-8-carboxylic acid methyl ester
BDBM50169777 (3S,4aR,6S,8R,8aR,10aR)-6-Acetoxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester CHEMBL178960
BDBM50246618 (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-N-benzyl-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxamide CHEMBL510912
BDBM683046 2-(1-(5-chloro-2-(difluoromethoxy)phenyl)-6-(pyrazolo[1,5-a]pyrimidin-3-yl)-1H-pyrazolo[4,3-b]pyridin-3-yl)-N,N-dimethylacetamide US20240209001, Example 4a
Biphenyl-2-carboxylic acid [3-chloro-4-((S)-3,4,11,11a-tetrahydro-1H,5H-2-oxa-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide; hydrochloride CHEMBL543854 BDBM50146284
Biphenyl-2-carboxylic acid [3-chloro-4-((S)-3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide; hydrochloride BDBM50146303 CHEMBL539285
CHEMBL1077648 (1S,4aS,6aS,6bR,8aS,11R,12aS,12bR,14bS)-benzyl 11-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate BDBM50310520
CHEMBL1078408 BDBM50310511 (1S,2R,4aS,6aS,6bR,8aS,12aS,12bR,14bS)-benzyl 1,2,6a,6b,9,9,12a-heptamethyl-11-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate
CHEMBL108028 BDBM50032797 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2-chloro-phenyl)-amide
CHEMBL108612 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2-amino-phenyl)-amide BDBM50032768
CHEMBL108875 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-methoxy-phenyl)-amide BDBM50032794
CHEMBL109170 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (4-chloro-phenyl)-amide BDBM50032787
CHEMBL180126 (3S,4aR,6S,8R,8aR,10aR)-3-Furan-3-yl-6-methoxymethoxy-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester BDBM50169772
CHEMBL195451 1-(4-fluorophenyl)-4',4a,6'-trimethyl-(4'R,4aS,6'R)-spiro[4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazole-5,2'-(dihydro-4'H-[1,3]dioxane)] BDBM50167793
CHEMBL25072 (4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid methyl-phenyl-amide BDBM50057476
CHEMBL264316 (4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid biphenyl-3-ylamide BDBM50057464
CHEMBL323788 BDBM50032774 (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-fluoro-phenyl)-amide
CHEMBL326439 BDBM50032775 (4aR,6aS)-4a,6a-Dimethyl-7-(2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one
CHEMBL360495 (3S,4aR,6S,8R,8aR,10aR)-3-Furan-3-yl-4a,8a-dimethyl-1,5-dioxo-6-propionyloxy-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester BDBM50169773
CHEMBL360553 (3S,4aR,6S,8R,8aR,10aR)-6-Cyclopropanecarbonyloxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester BDBM50169780
CHEMBL444286 BDBM50167809 1-(4-fluorophenyl)-4a-methyl-4',5'-di[(E)-1-propenyl]-(4'R,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)]
CHEMBL504397 BDBM50246742 (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(2-carboxybenzyloxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
CHEMBL508831 BDBM50246744 (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(4-carboxybenzyloxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid