Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 689
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287137BDBM287137(1-(1-(2-(azepan- 1-yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  6.70nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287087BDBM287087(N-(1-(2-(azepan-1-yl)ethyl)-1H-pyrazolo[3,4-d]pyri...)
Affinity DataKi:  9.20nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287138BDBM287138(1-(1-(2-(azepan- 1-yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  9.20nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287101BDBM287101(N-(1-(2-(Azepan-1- yl)ethyl)-1H-pyrazolo[3,4- d]py...)
Affinity DataKi:  9.40nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287111BDBM287111(N-(1-(2-(azepan-1- yl)ethyl)-1H-pyrazolo[3,4- d]py...)
Affinity DataKi:  11.1nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287140BDBM287140(N-(1-(2-(4-tert- butylpiperidin-1-yl)ethyl)- 1H-py...)
Affinity DataKi:  12.2nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287088BDBM287088(N-(1-[2-(Piperidin-1- yl)ethyl]-1H-pyrazolo[3,4- d...)
Affinity DataKi:  12.7nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287135BDBM287135(1-(1-(2-(azepan-1-yl)ethyl)-1H-pyrazolo[3,4-d]pyri...)
Affinity DataKi:  12.8nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287097BDBM287097(N-(1-(2-(Azepan-1- yl)ethyl)-1H-pyrazolo[3,4- d]py...)
Affinity DataKi:  13.1nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287136BDBM287136(1-(1-(2-(azepan- 1-yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  14.9nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287103BDBM287103(N-(1-(2-(Azepan-1- yl)ethyl)-1H-pyrazolo[3,4- d]py...)
Affinity DataKi:  15nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287107BDBM287107(N-(1-(2-(azepan-1- yl)ethyl)-1H-pyrazolo[3,4- d]py...)
Affinity DataKi:  16.4nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287119BDBM287119(1-(1-(2-(Azepan-1- yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  21.2nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287139BDBM287139(1-(1-(2-(azepan- 1-yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  21.8nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287132BDBM287132(1-(1-(2-(azepan-1- yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  23.4nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287129BDBM287129(1-(1-(2-(azepan-1- yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  24nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287093BDBM287093(N-(1-(2-(piperidin-1- yl)ethyl)-1H-pyrazolo[3,4- d...)
Affinity DataKi:  24.4nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287128BDBM287128(1-(1-(2-(azepan-1- yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  27.9nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287130BDBM287130(1-(1-(2-(azepan-1- yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  29nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287116BDBM287116(N-(1-(3-(azepan-1- yl)propyl)-1H-pyrazolo[3,4- d]p...)
Affinity DataKi:  32.7nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287126BDBM287126(1-(1-(2-(azepan-1- yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  41.4nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287143BDBM287143(N-(1-(3-(piperidin-1- yl)propyl)-1H- pyrazolo[3,4-...)
Affinity DataKi:  45.1nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287089BDBM287089(N-(1-(2-(Piperidin-1- yl)ethyl)-1H-pyrazolo[3,4- d...)
Affinity DataKi:  50.6nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287112BDBM287112(N-(1-(2-(azepan-1- yl)ethyl)-1H-pyrazolo[3,4- d]py...)
Affinity DataKi:  54.6nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287102BDBM287102(N-(1-(2- (Diisopropylamino)ethyl)- 1H-pyrazolo[3,4...)
Affinity DataKi:  55nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287100BDBM287100(N-(1-(2- (Diisopropylamino)ethyl)- 1H-pyrazolo[3,4...)
Affinity DataKi:  56.7nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287104BDBM287104(N-(1-(2-(Azepan-1- yl)ethyl)-1H-pyrazolo[3,4- d]py...)
Affinity DataKi:  58nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287115BDBM287115(N-(1-(4-(azepan-1- yl)butyl)-1H-pyrazolo[3,4- d]py...)
Affinity DataKi:  61.9nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287090BDBM287090(N-(1-(2-(Piperidin-1- yl)ethyl)-1H-pyrazolo[3,4- d...)
Affinity DataKi:  73.1nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287113BDBM287113(N-(1-(2-(pyrrolidin-1- yl)ethyl)-1H-pyrazolo[3,4- ...)
Affinity DataKi:  74.4nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287118BDBM287118(1-(1-(2-(Azepan-1- yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  78.7nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287147BDBM287147(1-(1-(2-(piperidin-1- yl)ethyl)-1H- pyrazolo[3,4- ...)
Affinity DataKi:  85.2nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287131BDBM287131(1-(1-(2-(azepan-1- yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  100nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287133BDBM287133(1-(1-(3-(azepan-1- yl)propyl)-1H- pyrazolo[3,4- d]...)
Affinity DataKi:  102nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287127BDBM287127(1-(1-(2-(azepan-1- yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  108nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287114BDBM287114(N-(1-(2-(pyrrolidin-1- yl)ethyl)-1H-pyrazolo[3,4- ...)
Affinity DataKi:  116nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287120BDBM287120(1-(1-(2-(Azepan-1- yl)ethyl)-1H- pyrazolo[3,4- d]p...)
Affinity DataKi:  119nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287124BDBM287124(1-(2,4-Dichlorophenyl)- 3-(1-(2-(piperidin-1- yl)e...)
Affinity DataKi:  142nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287110BDBM287110(N-(1-(2-(azepan-1- yl)ethyl)-1H-pyrazolo[3,4- d]py...)
Affinity DataKi:  156nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287123BDBM287123(1-Adamanthyl-3-(1-(2- (piperidin-1-yl)ethyl)-1H- p...)
Affinity DataKi:  182nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287141BDBM287141(N-(1-(2-(1,4-oxazepan-4- yl)ethyl)-1H-pyrazolo[3,4...)
Affinity DataKi:  184nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287121BDBM287121(1-Cyclopentyl-3-(1-(2- (piperidin-1-yl)ethyl)-1H- ...)
Affinity DataKi:  192nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287134BDBM287134(1-(1-(2-(4-tert- butylpiperidin-1- yl)ethyl)-1H- p...)
Affinity DataKi:  212nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287148BDBM287148(N-(1-(2-(azepan-1-yl)ethyl)-1H-pyrazolo[3,4-d]pyri...)
Affinity DataKi:  221nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287098BDBM287098(N-(1-(2- (Diisopropylamino)ethyl)- 1H-pyrazolo[3,4...)
Affinity DataKi:  244nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287117BDBM287117(1-(1-(2-(1,4-oxazepan-4-yl)ethyl)-1H-pyrazolo[3,4-...)
Affinity DataKi:  252nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287146BDBM287146(1-(1-(4-(4-tert- butylpiperidin-1- yl)butyl)-1H- p...)
Affinity DataKi:  280nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287091BDBM287091(2,4-Dichloro-N-(1-(2- (piperidin-1-yl)ethyl)-1H- p...)
Affinity DataKi:  292nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287144BDBM287144(N-(1-(3-(4- methylpiperazin-1- yl)propyl)-1H- pyra...)
Affinity DataKi:  329nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratorios Del Dr. Esteve

US Patent
LigandChemical structure of BindingDB Monomer ID 287122BDBM287122(1-Ethyl-3-(1-(2- (piperidin-1-yl)ethyl)-1H- pyrazo...)
Affinity DataKi:  371nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

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