Compile Data Set for Download or QSAR
Report error Found 371 Enz. Inhib. hit(s) with all data for entry = 3084
TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM50260067(US9957263, Example 78 | CHEMBL4078267)
Affinity DataKi:  0.600nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390899(US9957263, Example 163 | N-{4-(2,4-difluorophenoxy...)
Affinity DataKi:  0.605nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM50156345(CHEMBL3787680 | US9957263, Example 149)
Affinity DataKi:  0.669nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390749(US9957263, Example 11)
Affinity DataKi:  0.800nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM50260067(US9957263, Example 78 | CHEMBL4078267)
Affinity DataKi:  0.900nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390787(US9957263, Example 49)
Affinity DataKi:  1nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390749(US9957263, Example 11)
Affinity DataKi:  1nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390791(US9957263, Example 53)
Affinity DataKi:  1nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390790(US9957263, Example 52)
Affinity DataKi:  1.10nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM50260084(US9957263, Example 110 | CHEMBL4096313)
Affinity DataKi:  1.10nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390813(US9957263, Example 76)
Affinity DataKi:  1.10nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390792(US9957263, Example 54)
Affinity DataKi:  1.10nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390788(US9957263, Example 50)
Affinity DataKi:  1.20nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390798(US9957263, Example 61)
Affinity DataKi:  1.30nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM50260065(US9957263, Example 63 | CHEMBL4088597)
Affinity DataKi:  1.30nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390811(US9957263, Example 74)
Affinity DataKi:  1.40nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390799(US9957263, Example 62)
Affinity DataKi:  1.40nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390746(US9957263, Example 8)
Affinity DataKi:  1.5nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390924(US9957263, Example 188)
Affinity DataKi:  1.56nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390750(US9957263, Example 12)
Affinity DataKi:  1.60nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390806(US9957263, Example 69)
Affinity DataKi:  1.60nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390845(US9957263, Example 109)
Affinity DataKi:  1.60nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390870(US9957263, Example 134)
Affinity DataKi:  1.62nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390899(US9957263, Example 163 | N-{4-(2,4-difluorophenoxy...)
Affinity DataKi:  1.64nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390803(US9957263, Example 66)
Affinity DataKi:  1.70nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390747(US9957263, Example 9)
Affinity DataKi:  1.70nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM50260066(US9957263, Example 4 | CHEMBL4067346)
Affinity DataKi:  1.70nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390743(US9957263, Example 5)
Affinity DataKi:  1.70nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390746(US9957263, Example 8)
Affinity DataKi:  1.80nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390750(US9957263, Example 12)
Affinity DataKi:  1.80nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390784(US9957263, Example 46)
Affinity DataKi:  1.80nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390773(US9957263, Example 35)
Affinity DataKi:  1.90nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390776(US9957263, Example 38)
Affinity DataKi:  1.90nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390778(US9957263, Example 40)
Affinity DataKi:  2nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390747(US9957263, Example 9)
Affinity DataKi:  2nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390790(US9957263, Example 52)
Affinity DataKi:  2nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390797(US9957263, Example 60)
Affinity DataKi:  2nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390744(US9957263, Example 6)
Affinity DataKi:  2nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390802(US9957263, Example 65)
Affinity DataKi:  2.10nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM50260068(US9957263, Example 39 | CHEMBL4075943)
Affinity DataKi:  2.10nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390782(US9957263, Example 44)
Affinity DataKi:  2.10nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390795(US9957263, Example 57)
Affinity DataKi:  2.20nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM50260084(US9957263, Example 110 | CHEMBL4096313)
Affinity DataKi:  2.20nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390880(US9957263, Example 144 | N-[4-(diethylamino)butyl]...)
Affinity DataKi:  2.34nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390786(US9957263, Example 48)
Affinity DataKi:  2.40nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390796(US9957263, Example 58)
Affinity DataKi:  2.40nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390754(US9957263, Example 16)
Affinity DataKi:  2.5nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390914(US9957263, Example 178)
Affinity DataKi:  2.5nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390849(US9957263, Example 113)
Affinity DataKi:  2.5nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390923(US9957263, Example 187)
Affinity DataKi:  2.52nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

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