Compound (942)
Article Title (19)
Article Author (14)
Assay (18)
PubChem, PC MKP-3 in vitro HTS assay PubChem Bioassay (2009) Cao, S; Murphy, BT; Foster, C; Lazo, JS; Kingston, DG Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. Bioorg Med Chem 17: 2276 -81 (2009) PubChem, PC In Vitro MKP-3 Dose Response Assay for SAR Study PubChem Bioassay (2008) PubChem, PC In vitro MKP-1 Phosphatase Dose Response SAR Support Assay PubChem Bioassay (2007) PubChem, PC In vitro MKP-1 Phosphatase HTS Dose Response Confirmation Assay PubChem Bioassay (2007) PubChem, PC In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay PubChem Bioassay (2007) PubChem, PC In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing PubChem Bioassay (2006) PubChem, PC In vitro MKP-1 Phosphatase Dose Response Confirmation and Secondary Selectivity/Specificity Assay PubChem Bioassay (2006) PubChem, PC In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing PubChem Bioassay (2007) PubChem, PC In vitro MKP-3 Phosphatase Dose Response Confirmation and Secondary Selectivity/Selectivity Assay PubChem Bioassay (2006) PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-1 Dose Response Selectivity comparison. PubChem Bioassay (2007) PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-3 Dose Response Selectivity comparison. PubChem Bioassay (2007) PubChem, PC In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of Catalase PubChem Bioassay (2006) PubChem, PC In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of DTT PubChem Bioassay (2006) PubChem, PC In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of Catalase PubChem Bioassay (2006) PubChem, PC MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment: Cdc25B Dose Response Selectivity Assay PubChem Bioassay (2007) PubChem, PC MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors PubChem Bioassay (2008) Borsari, C; Keles, E; Rageot, D; Treyer, A; Bohnacker, T; Bissegger, L; De Pascale, M; Melone, A; Sriramaratnam, R; Beaufils, F; Hamburger, M; Hebeisen, P; Löscher, W; Fabbro, D; Hillmann, P; Wymann, MP 4-(Difluoromethyl)-5-(4-((3 J Med Chem 63: 13595 -13617 (2020) Brown, BH; Carra, EA; Hemenway, JN; Morrison, H; Reynolds, T; Shi, B; Stefanidis, D; Wang, F; Warr, MR; Whitney, JA; Xin, Y (N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide US Patent US9469613 (2016)
Moser, PC; Bergis, OE; Jegham, S; Lochead, A; Duconseille, E; Terranova, JP; Caille, D; Berque-Bestel, I; Lezoualc'h, F; Fischmeister, R; Dumuis, A; Bockaert, J; George, P; Soubrié, P; Scatton, B J Pharmacol Exp Ther 302: 731 -41 (2002) Machulkin, AE; Uspenskaya, AA; Zyk, NU; Nimenko, EA; Ber, AP; Petrov, SA; Polshakov, VI; Shafikov, RR; Skvortsov, DA; Plotnikova, EA; Pankratov, AA; Smirnova, GB; Borisova, YA; Pokrovsky, VS; Kolmogorov, VS; Vaneev, AN; Khudyakov, AD; Chepikova, OE; Kovalev, S; Zamyatnin, AA; Erofeev, A; Gorelkin, P; Beloglazkina, EK; Zyk, NV; Khazanova, ES; Majouga, AG J Med Chem 64: 17123 -17145 (2021) Zindo, FT; Malan, SF; Omoruyi, SI; Enogieru, AB; Ekpo, OE; Joubert, J Eur J Med Chem 163: 83 -94 (2019) Hutt, OE; Saubern, S; Winkler, DA Bioorg Med Chem 19: 5903 -11 (2011) Eldehna, WM; Abo-Ashour, MF; Nocentini, A; Gratteri, P; Eissa, IH; Fares, M; Ismael, OE; Ghabbour, HA; Elaasser, MM; Abdel-Aziz, HA; Supuran, CT Eur J Med Chem 139: 250 -262 (2017) Narwal, M; Koivunen, J; Haikarainen, T; Obaji, E; Legala, OE; Venkannagari, H; Joensuu, P; Pihlajaniemi, T; Lehtiö, L J Med Chem 56: 7880 -9 (2013) Levy, OE; Taibi, P; Mobashery, S; Ghosh, SS J Med Chem 36: 2408 -11 (1993) Holmes, IP; Blunt, RJ; Lorthioir, OE; Blowers, SM; Gribble, A; Payne, AH; Stansfield, IG; Wood, M; Woollard, PM; Reavill, C; Howes, CM; Micheli, F; Di Fabio, R; Donati, D; Terreni, S; Hamprecht, D; Arista, L; Worby, A; Watson, SP Bioorg Med Chem Lett 20: 2013 -6 (2010) Koval, VS; Arutyunyan, AF; Salyanov, VI; Kostyukov, AA; Melkina, OE; Zavilgelsky, GB; Klimova, RR; Kushch, AA; Korolev, SP; Agapkina, YY; Gottikh, MB; Vaiman, AV; Rybalkina, EY; Susova, OY; Zhuze, AL Bioorg Med Chem 28: (2020) Ellis, ES; Byrne, C; Murphy, OE; Tilford, NS; Baxter, GS Br J Pharmacol 114: 400 -4 (1995) KUMAGAI, Y; UMEHARA, H; OISHI, J; KAWAKAMI, R; INAGAKI, R; OE, S; SHIMIZU, K; OTA, Y US Patent US20250352541 (2025) Ozaki, S; Oe, H; Kitamura, S J Nat Prod 71: 981 -4 (2008) Naka, Y; Yamada, I; Ochi, H; Matsuura, M; Nagamatsu, Y; Oe, T Bioorg Med Chem Lett 5: 959 -962 (1995) Harada, K; Mizukami, J; Kadowaki, S; Matsuda, I; Watanabe, T; Oe, Y; Kodama, Y; Aoki, K; Suwa, K; Fukuda, S; Yata, S; Inaba, T Bioorg Med Chem Lett 28: 1228 -1233 (2018)
In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibitors of actives identified in the MKP-3 HTS run at (Burham Institute) SDCCG center AID 425 and the MKP-1 HTS run at the PMLSC AID 374, and subsequently confirmed in the MKP-3 & MKP-1 HTS dose response confirmation assays AID's 553 & 551. The in vitro MKP-3 Phosphatase dose response hit/probe assessment reproducibility testing assay has been developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library Screening Center Network (MLSCN). XO1 submission MH-76390 In vitro HTS assay for MKP-3, Assay Provider Dr. John S. Lazo, Department of Pharmacology at the University of Pittsburgh. The 107 protein tyrosine phosphatases (PTPs) found in the human genome are defined by the active site sequence C(X)5R(S/T), with X being any amino acid, and they are critical regulators of mammalian cell pr In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of Catalase The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3 inhibition of actives identified in the MKP-3 HTS run at (Burham Institute) SDCCG center AID 425 and the MKP-1 HTS run at the PMLSC AID 374, and subsequently confirmed in the MKP-3 & MKP-1 HTS dose response confirmation assays AID's 553 & 551. Protein tyrosine phosphatases have an active site cysteine that is very susceptible to inactivation by oxidation. In addition, a number of compounds such as quinone-like compounds are capable of generating reactive oxygen species via redox cycling in the presence of DTT. Adding Catalase to inactivate hydrogen peroxide (H2O2)does not affect the activity of MKP-3 in the assay but can reverse the inhibition of some inhibitors or significantly increase their IC50 values. The MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of Catalase has been Developed and Run at the Univers In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibitors identified in the MH-76391 In vitro HTS assay for MKP-1 inhibitors AID #374 and subsequently confirmed in the MKP-1 HTS dose response confirmation assay AID # 551.The MKP-1 Phosphatase dose response assay Active/Probe Assessment Assay - Reproducibility testing has been Developed and Run at the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library Screening Center Network (MLSCN). XO1 submission MH-76391 In vitro HTS assay for MKP-1, Assay Provider Dr. John S. Lazo, Department of Pharmacology at the University of Pittsburgh. The 107 protein tyrosine phosphatases (PTPs) found in the human genome are defined by the active site sequence C(X)5R(S/T), with X being any amino acid, and they are critical regulators of mammalian cell proliferation, differentiation, and apoptosis. PTPs can be divided into at In vitro MKP-1 Phosphatase Dose Response SAR Support Assay The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemistry Core based on MKP-1 inhibitors identified in the MH-76391 In vitro HTS assay for MKP-1 inhibitors AID 374 and subsequently confirmed in the MKP-1 HTS dose response confirmation assay AID 551. The MKP-1 Phosphatase dose response SAR support assay has been Developed and Run at the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library Screening Center Network (MLSCN). XO1 submission MH-76391 In vitro HTS assay for MKP-1, Assay Provider Dr. John S. Lazo, Department of Pharmacology at the University of Pittsburgh. The 107 protein tyrosine phosphatases (PTPs) found in the human genome are defined by the active site sequence C(X)5R(S/T), with X being any amino acid, and they are critical regulators of mammalian cell proliferation, differentiation, and apoptosis. PTPs can be divided into at least four s H6PD Activity Assay HEK293 H6PD-OE and HEK293 pellets were lysed and the lysate was quantified with the Bradford protein assay. Reaction mix containing galactose-6-phosphate (Gal6P) was combined with increasing concentrations of PARPi or DMSO. As an additional control, reaction mix without substrate was combined with HEK293 H6PD-OE lysate. Lysate from HEK293 or HEK293 H6PD-OE was added to each well to start the reactions. The absorbance at 340 nM (NADPH) was measured for 90 min at 10 min intervals. The 60 min data, which were within the linear range, was used for analysis. Background absorbance was subtracted and the H6PD activity of theHEK293 H6PD-OE lysates treated with PARPi was normalized to the DMSO control. In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of Catalase The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1 inhibition of actives identified in the MH-76391 In vitro MKP-1 HTS assay AID #374, and subsequently confirmed in the HTS dose response confirmation assay AID #551. Protein tyrosine phosphatases have an active site cysteine that is very susceptible to inactivation by oxidation. In addition, a number of compounds such as quinone-like compounds are capable of generating reactive oxygen species via redox cycling in the presence of DTT. Adding Catalase to inactivate hydrogen peroxide (H2O2)does not affect the activity of MKP-1 in the assay but can reverse the inhibition of some inhibitors or significantly increase their IC50 values.The MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of Catalase has been Developed and Run at the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library S In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of DTT The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhibition of actives identified in the MH-76391 In vitro MKP-1 HTS assay AID #374, and subsequently confirmed in the HTS dose response confirmation assay AID #551. Protein tyrosine phosphatases have an active site cysteine that is very susceptible to inactivation by oxidation. In addition, a number of compounds such as quinone-like compounds are capable of generating reactive oxygen species via redox cycling in the presence of DTT. Increasing the concentration of DTT from 1 mM to 25 mM does not affect the activity of MKP-1 in the assay but can reverse the inhibition of some inhibitors or significantly increase their IC50 values. The MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay-Effects of DTT has been Developed and Run at the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library Screening In Vitro MKP-3 Dose Response Assay for SAR Study Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: NIH Molecular Libraries Screening Centers Network (MLSCN) Grant Number: XO1 MH076390-01 Assay Provider: Dr. John Lazo, University of Pittsburg This MKP-3 dose response assay is developed and performed for the purpose of SAR study on analogs of hits originally identified in the MKP-3 in vitro HTS assay (AID 425) MKP-3 (mitogen-activated protein kinase phosphatase-3; EC 3.1.3.48, EC 3.1.3.16), a dual specificity phosphatase negatively regulates ERK1/2 by catalyzing the removal of a phosphoryl group from Thr(P) and Tyr(P) in the activation loop consensus motif -pTXpY. MKP-3 screening was performed using a biochemical assay developed at the laboratory of Prof. John Lazo (University of Pittsburg). The assay was optimized and run at the Burnham Center for Chemical Genomics (BCCG) as part of the Molecular Library Screening Center Network (MLSCN ChEMBL_2437212 Inhibition of mouse MKP-5 (320 to 647 residues) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fluorescence based assay In vitro MKP-1 Phosphatase HTS Dose Response Confirmation Assay The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibitors screened at the PMLSC AID #374.The MKP-1 Phosphatase HTS Dose Response Confirmation Assay has been Developed and Run at the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library Screening Center Network (MLSCN). XO1 submission MH-76391 In vitro HTS assay for MKP-1, Assay Provider Dr. John S. Lazo, Department of Pharmacology at the University of Pittsburgh. The 107 protein tyrosine phosphatases (PTPs) found in the human genome are defined by the active site sequence C(X)5R(S/T), with X being any amino acid, and they are critical regulators of mammalian cell proliferation, differentiation, and apoptosis. PTPs can be divided into at least four subfamilies based on their tertiary structure: Classical phosphotyrosine specific PTPs, dual specificity phosphatases (DSPase), Cdc25 phosphatases and low mole In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library Screening Center Network (MLSCN)to follow up on actives identified in the MKP-3 HTS run at (Burham Institute) SDCCG center AID # 425 and the MKP-1 HTS run at the PMLSC AID # 374. XO1 submission MH-76390 In vitro HTS assay for MKP-3, Assay Provider Dr. John S. Lazo, Department of Pharmacology at the University of Pittsburgh. The 107 protein tyrosine phosphatases (PTPs) found in the human genome are defined by the active site sequence C(X)5R(S/T), with X being any amino acid, and they are critical regulators of mammalian cell proliferation, differentiation, and apoptosis. PTPs can be divided into at least four subfamilies based on their tertiary structure: Classical phosphotyrosine specific PTPs, dual specificity phosphatases (DSPase), Cdc25 phosphatases and low molecular weight PTPs. One MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment: Cdc25B Dose Response Selectivity Assay The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PTP selectivity of actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibitors. The MKP-1 HTS assay was screened by the PMLSC against the year 1 full diversity NIH compound library (65,239 compounds) and the data were uploaded to the PubChem database AID 374. The PMLSC confirmed the actives from the MKP-1 screen in dose response assays and uploaded the data to the PubChem database AID 551. The 107 protein tyrosine phosphatases (PTPs) found in the human genome are defined by the active site sequence C(X)5R(S/T), with X being any amino acid, and they are critical regulators of mammalian cell proliferation, differentiation, and apoptosis. PTPs can be divided into at least four subfamilies based on their tertiary structure: Classical phosphotyrosine specific PTPs, dual specificity phosphatases (DSPase), Cdc25 phosphatases and In vitro MKP-1 Phosphatase Dose Response Confirmation and Secondary Selectivity/Specificity Assay The MKP-1 Phosphatase Dose Response Confirmation and Secondary Selectivity/Specificity Assay has been Developed and Run at the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library Screening Center Network (MLSCN). XO1 submission MH-76391 In vitro HTS assay for MKP-1, Assay Provider Dr. John S. Lazo, Department of Pharmacology at the University of Pittsburgh. The 107 protein tyrosine phosphatases (PTPs) found in the human genome are defined by the active site sequence C(X)5R(S/T), with X being any amino acid, and they are critical regulators of mammalian cell proliferation, differentiation, and apoptosis. PTPs can be divided into at least four subfamilies based on their tertiary structure: Classical phosphotyrosine specific PTPs, dual specificity phosphatases (DSPase), Cdc25 phosphatases and low molecular weight PTPs. One subgroup of the DSPase family are the MAPK phosphatases (MKP), which dephosphorylate MAPKs on threonine and tyrosine residues. In vitro MKP-3 Phosphatase Dose Response Confirmation and Secondary Selectivity/Selectivity Assay The MKP-3 Phosphatase Secondary Selectivity Assay has been developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library Screening Center Network (MLSCN). XO1 submission MH-76390 In vitro HTS assay for MKP-3, Assay Provider Dr. John S. Lazo, Department of Pharmacology at the University of Pittsburgh. The 107 protein tyrosine phosphatases (PTPs) found in the human genome are defined by the active site sequence C(X)5R(S/T), with X being any amino acid, and they are critical regulators of mammalian cell proliferation, differentiation, and apoptosis. PTPs can be divided into at least four subfamilies based on their tertiary structure: Classical phosphotyrosine specific PTPs, dual specificity phosphatases (DSPase), Cdc25 phosphatases and low molecular weight PTPs. One subgroup of the DSPase family are the MAPK phosphatases (MKP), which dephosphorylate MAPKs on threonine and tyrosine residues. Nine members of the DSPases have been c MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA) Network: NIH Molecular Libraries Screening Centers Network (MLSCN) Grant Number: XO1 MH076390-01 Assay Provider: Dr. John Lazo, University of Pittsburg This assay is designed as a counter-screen for the MKP-3 in vitro HTS assay (AID 425) aimed at identification of compounds with time-dependent behavior. MKP-3 (mitogen-activated protein kinase phosphatase-3; EC 3.1.3.48, EC 3.1.3.16), a dual specificity phosphatase negatively regulates ERK1/2 by catalyzing the removal of a phosphoryl group from Thr(P) and Tyr(P) in the activation loop consensus motif -pTXpY. MKP-3 has a labile cysteine in its active site that is crucial for the catalysis. As a result compounds capable of cysteine oxidation or modification are likely to appear as screening hits. The current biochemical assay is designed as a rapid diagnostic tool for identification of MKP-3 in vitro HTS assay Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) Network: NIH Molecular Libraries Screening Centers Network (MLSCN) Grant Number: XO1 MH076390-01 Assay Provider: Dr. John Lazo, University of Pittsburg MKP-3 (mitogen-activated protein kinase phosphatase-3; EC 3.1.3.48, EC 3.1.3.16), a dual specificity phosphatase negatively regulates ERK1/2 by catalyzing the removal of a phosphoryl group from Thr(P) and Tyr(P) in the activation loop consensus motif -pTXpY. MKP-3 screening was performed using a biochemical assay developed at the laboratory of Prof. John Lazo (University of Pittsburg). The assay was optimized and run at the Sanford-Burnham Center for Chemical Genomics (SBCCG) as part of the Molecular Library Screening Center Network (MLSCN). Enzyme activity and its inhibition by screened compounds was measured in an end-point assay based on hydrolysis of 3-O-methylfluorescein phosphate Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-1 Dose Response Selectivity comparison. The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that were identified in the Cdc25B HTS AID 368 and confirmed in the Cdc25B 10-pt dose response confirmation assay AID 569 conducted by the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library Screening Center Network (MLSCN). XO1 submission MH078959 Cdc25B catalytic domain in vitro assay, Assay Provider Dr. Marni Brisson, Department of Pharmacology at the University of Pittsburgh. The 107 protein tyrosine phosphatases (PTPs) found in the human genome are defined by the active site sequence C(X)5R(S/T), with X being any amino acid, and they are critical regulators of mammalian cell proliferation, differentiation, and apoptosis. PTPs can be divided into at least four subfamilies based on their tertiary structure: Classical phosphotyrosine specific PTPs, dual specificity phosphatases (DSPase), Cdc25 phosph Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-3 Dose Response Selectivity comparison. The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that were identified in the Cdc25B HTS AID 368 and confirmed in the Cdc25B 10-pt dose response confirmation assay AID 569 conducted by the University of Pittsburgh Molecular Screening Center (PMLSC) part of the Molecular Library Screening Center Network (MLSCN). XO1 submission MH078959 Cdc25B catalytic domain in vitro assay, Assay Provider Dr. Marni Brisson, Department of Pharmacology at the University of Pittsburgh. The 107 protein tyrosine phosphatases (PTPs) found in the human genome are defined by the active site sequence C(X)5R(S/T), with X being any amino acid, and they are critical regulators of mammalian cell proliferation, differentiation, and apoptosis. PTPs can be divided into at least four subfamilies based on their tertiary structure: Classical phosphotyrosine specific PTPs, dual specificity phosphatases (DSPase), Cdc25 phosph
BDBM573947 US11453697, Example 132 2-amino-9-[(5S,7R,8R,12aR,14R,15S,15aR)- 14-(6-amino-9H-purin-9-yl)-15-fluoro-2,10- dihydroxy-2,10-disulfidooctahydro-12H-5,8- methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]-1,9- dihydro-6H-purin-6-oe (Diastereomer 3)
US12358931, Example 4-4 US10072026, Example 4-4 US10947254, Example 4-4 US11780852, Example 4-4 BDBM277513
4-(4-methoxyphenoxy)-N-(4-morpholin-4-ylsulfonylphenyl)butanamide MLS002163565 SMR001245952 BDBM79220 cid_4854010 4-(4-methoxyphenoxy)-N-[4-(4-morpholinylsulfonyl)phenyl]butanamide 4-(4-methoxyphenoxy)-N-(4-morpholinosulfonylphenyl)butyramide
4-(4-methylphenoxy)-N-(4-morpholin-4-ylsulfonylphenyl)butanamide SMR001239000 MLS002156496 BDBM79222 4-(4-methylphenoxy)-N-[4-(4-morpholinylsulfonyl)phenyl]butanamide cid_8151579 4-(4-methylphenoxy)-N-(4-morpholinosulfonylphenyl)butyramide
BDBM63263 N-(4-nitrophenyl)-4-phenyl-tetrahydropyran-4-carboxamide N-(4-nitrophenyl)-4-phenyltetrahydro-2H-pyran-4-carboxamide SMR000269420 MLS000681152 N-(4-nitrophenyl)-4-phenyl-4-oxanecarboxamide N-(4-nitrophenyl)-4-phenyloxane-4-carboxamide cid_2901255 N-(4-nitrophenyl)-4-phenyl-oxane-4-carboxamide
N-[4-(4-bromoanilino)-4-oxobutyl]-4-chlorobenzamide BDBM95806 SMR000595772 N-[4-(4-bromoanilino)-4-keto-butyl]-4-chloro-benzamide cid_9327903 MLS001177055 N-[4-[(4-bromophenyl)amino]-4-oxidanylidene-butyl]-4-chloranyl-benzamide
4'-(4-toluenesulfonamido)-4-hydroxychalcone BDBM50174835 N-(4-(3-(4-hydroxyphenyl)acryloyl)phenyl)-4-methylbenzenesulfonamide 4'-(p-Toluenesulfonamide)-4-hydroxychalcone Sulfonamide chalcone, 4 CHEMBL371723
N-(4-chlorophenyl)-4-morpholinosulfonyl-benzamide SMR000606966 MLS001223984 N-(4-chlorophenyl)-4-morpholin-4-ylsulfonylbenzamide N-(4-chlorophenyl)-4-(4-morpholinylsulfonyl)benzamide BDBM60333 N-(4-Chloro-phenyl)-4-(morpholine-4-sulfonyl)-benzamide N-(4-chlorophenyl)-4-morpholin-4-ylsulfonyl-benzamide cid_1548697
SMR001270698 BDBM76240 cid_25162239 N'-[1,4-dioxo-4-(4-pentoxyphenyl)butyl]-4-pyridinecarbohydrazide N'-[4-(4-amoxyphenyl)-4-keto-butanoyl]isonicotinohydrazide MLS002181668 N'-[4-oxo-4-(4-pentoxyphenyl)butanoyl]pyridine-4-carbohydrazide N'-[4-oxidanylidene-4-(4-pentoxyphenyl)butanoyl]pyridine-4-carbohydrazide
BDBM136587 US10005783, 4 US11267818, Example 4 US10047097, 4 US9676783, 4 US10774085, Example 4 US8865698, 4
BDBM256625 US10414761, Example 4 US9920047, 4 US9487511, 4 US9718814, 4 US10053456, 4 US10968213, Example 4
(4-chlorophenyl) 4-[(4-anilino-4-oxobutanoyl)oxymethyl]benzoate 4-[(4-anilino-1,4-dioxobutoxy)methyl]benzoic acid (4-chlorophenyl) ester (4-chlorophenyl) 4-[(4-oxidanylidene-4-phenylazanyl-butanoyl)oxymethyl]benzoate 4-[(4-anilino-4-keto-butanoyl)oxymethyl]benzoic acid (4-chlorophenyl) ester 4-chlorophenyl 4-{[(4-anilino-4-oxobutanoyl)oxy]methyl}benzoate MLS000583227 BDBM56531 cid_1243594 SMR000201061
4-(4-morpholinylsulfonyl)-N-[4-(pyridin-4-ylmethyl)phenyl]benzamide 4-morpholin-4-ylsulfonyl-N-[4-(pyridin-4-ylmethyl)phenyl]benzamide cid_1267735 MLS000043991 BDBM46343 4-(morpholin-4-ylsulfonyl)-N-[4-(pyridin-4-ylmethyl)phenyl]benzamide 4-morpholinosulfonyl-N-[4-(4-pyridylmethyl)phenyl]benzamide SMR000021402
4-(4-tert-butylphenyl)-2-[(4-chlorophenyl)thio]-4-oxobutanoic acid 4-[4-(tert-butyl)phenyl]-2-[(4-chlorophenyl)sulfanyl]-4-oxobutanoic acid BDBM47659 4-(4-tert-butylphenyl)-2-(4-chlorophenyl)sulfanyl-4-oxidanylidene-butanoic acid SMR000338499 4-(4-tert-butylphenyl)-2-[(4-chlorophenyl)thio]-4-keto-butyric acid MLS000736249 cid_4251978 4-(4-tert-butylphenyl)-2-(4-chlorophenyl)sulfanyl-4-oxobutanoic acid
MLS000098355 4-oxidanylidene-4-(4-propylphenyl)butanoic acid 4-oxo-4-(4-propylphenyl)butanoic acid SMR000062594 BDBM73278 4-keto-4-(4-propylphenyl)butyric acid cid_725542
BDBM405819 US10351547, Compound 4-4 US10597377, Compound 4-4
4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide CHEMBL80732 BDBM50128656 4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid hydroxyamide
cid_331833 [4-(4-hydroxybenzoyl)phenyl]-(4-hydroxyphenyl)methanone (4-hydroxyphenyl)-[4-[(4-hydroxyphenyl)-oxomethyl]phenyl]methanone MLS000523326 (4-hydroxyphenyl)-[4-(4-hydroxyphenyl)carbonylphenyl]methanone [4-(4-Hydroxy-benzoyl)-phenyl]-(4-hydroxy-phenyl)-methanone BDBM57056 SMR000123304
1-[4-Biphenyl-4-yl-4-(4-chloro-phenyl)-butyl]-4-(4-chloro-phenyl)-piperidin-4-ol CHEMBL199035 BDBM50027195
[4-(4-fluorophenyl)piperazino]-(4-pyridyl)methanone [4-(4-fluorophenyl)piperazin-1-yl]-pyridin-4-ylmethanone BDBM62948 1-(4-fluorophenyl)-4-isonicotinoylpiperazine cid_2164976 [4-(4-fluorophenyl)-1-piperazinyl]-pyridin-4-ylmethanone MLS000535428 SMR000142863 [4-(4-fluorophenyl)piperazin-1-yl]-pyridin-4-yl-methanone
4-morpholinyl-[4-(4-morpholinyl)phenyl]methanethione morpholino-(4-morpholinophenyl)methanethione 4-[4-(4-morpholinylcarbonothioyl)phenyl]morpholine BDBM34436 SMR000073585 cid_893573 morpholin-4-yl-(4-morpholin-4-ylphenyl)methanethione MLS000048262
CHEMBL78909 BDBM50128649 1-(4-methoxybenzyl)-4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide 4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-(4-methoxy-benzyl)-piperidine-4-carboxylic acid hydroxyamide
MLS000755676 cid_4358655 4-(4-methylphenoxy)-N-(4-pyridylmethyl)benzamide 4-(4-methylphenoxy)-N-(pyridin-4-ylmethyl)benzamide 4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzenecarboxamide BDBM46421 SMR000337350
4-[4-(4-bromophenyl)-1,3-thiazol-2-yl]pyridine 4-(4-bromophenyl)-2-(4-pyridyl)thiazole 4-(4-bromophenyl)-2-pyridin-4-yl-1,3-thiazole cid_738484 SMR000229804 4-(4-bromophenyl)-2-pyridin-4-ylthiazole MLS000698918 BDBM93796
(4-morpholinophenyl)-(4-pyridylmethyl)amine cid_788565 4-morpholin-4-yl-N-(pyridin-4-ylmethyl)aniline BDBM59414 4-(4-morpholinyl)-N-(4-pyridinylmethyl)aniline 4-(4-morpholinyl)-N-(pyridin-4-ylmethyl)aniline MLS000533896 SMR000141333
4-(4-tert-butylphenyl)-4-keto-2-(p-tolylthio)butyric acid BDBM43225 4-[4-(tert-butyl)phenyl]-2-[(4-methylphenyl)sulfanyl]-4-oxobutanoic acid MLS000736261 SMR000338511 4-(4-tert-butylphenyl)-2-(4-methylphenyl)sulfanyl-4-oxobutanoic acid cid_4253856 4-(4-tert-butylphenyl)-2-[(4-methylphenyl)thio]-4-oxobutanoic acid 4-(4-tert-butylphenyl)-2-(4-methylphenyl)sulfanyl-4-oxidanylidene-butanoic acid
cid_5108589 methyl 4-(4-chlorophenyl)-2-(4-isopropylphenyl)-4-oxobutanoate methyl 4-(4-chlorophenyl)-4-oxidanylidene-2-(4-propan-2-ylphenyl)butanoate MLS000325882 methyl 4-(4-chlorophenyl)-4-oxo-2-(4-propan-2-ylphenyl)butanoate 4-(4-chlorophenyl)-4-keto-2-p-cumenyl-butyric acid methyl ester BDBM55497 4-(4-chlorophenyl)-4-oxo-2-(4-propan-2-ylphenyl)butanoic acid methyl ester SMR000170016
4-{2-[(4-methoxybenzoyl)oxy]ethyl}-4-methylmorpholin-4-ium 4-methoxybenzoic acid 2-(4-methylmorpholin-4-ium-4-yl)ethyl ester;iodide cid_16187871 SMR000306287 4-methoxybenzoic acid 2-(4-methyl-4-morpholin-4-iumyl)ethyl ester;iodide BDBM48782 MLS000727590 2-(4-methylmorpholin-4-ium-4-yl)ethyl 4-methoxybenzoate;iodide
MLS001004790 N-(4-morpholinophenyl)-2-(4-pyridyl)cinchoninamide SMR000348292 cid_2321599 N-[4-(4-morpholinyl)phenyl]-2-pyridin-4-yl-4-quinolinecarboxamide BDBM63762 N-(4-morpholin-4-ylphenyl)-2-pyridin-4-ylquinoline-4-carboxamide N-(4-morpholin-4-ylphenyl)-2-pyridin-4-yl-quinoline-4-carboxamide
4-(4-chlorophenyl)-2-(4-pyridyl)thiazole 4-(4-chlorophenyl)-2-pyridin-4-ylthiazole MLS000706668 BDBM93806 SMR000288120 cid_2806768 4-(4-chlorophenyl)-2-pyridin-4-yl-1,3-thiazole
4-(4-fluorophenyl)-2-pyridin-4-yl-1,3-thiazole BDBM93810 SMR000288121 cid_738487 4-(4-fluorophenyl)-2-pyridin-4-ylthiazole MLS000706669 4-(4-fluorophenyl)-2-(4-pyridyl)thiazole
4-(4-hydroxyphenyl)-N-(4-morpholin-4-ylsulfonylphenyl)piperazine-1-carbothioamide MLS000761338 cid_3937050 SMR000370246 4-(4-hydroxyphenyl)-N-[4-(4-morpholinylsulfonyl)phenyl]-1-piperazinecarbothioamide BDBM59019 4-(4-hydroxyphenyl)-N-(4-morpholinosulfonylphenyl)piperazine-1-carbothioamide
N-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-(morpholin-4-ylmethyl)benzamide N-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-(morpholinomethyl)benzamide MLS000703395 SMR000273859 N-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-(4-morpholinylmethyl)benzamide cid_1163593 BDBM54321
4-(4-methylpiperazin-1-yl)-2-pyridin-4-ylquinazoline 4-(4-methylpiperazin-1-yl)-2-pyridin-4-yl-quinazoline BDBM37917 SMR000070500 4-(4-methyl-1-piperazinyl)-2-(4-pyridinyl)quinazoline 4-(4-methyl-1-piperazinyl)-2-pyridin-4-ylquinazoline cid_820817 4-(4-methylpiperazino)-2-(4-pyridyl)quinazoline MLS000099110
4-[(4-nitrophenyl)amino]-4-oxidanylidene-3-(phenylmethyl)butanoic acid MLS000574566 BDBM59928 4-(4-nitroanilino)-4-oxo-3-(phenylmethyl)butanoic acid SMR000195992 3-benzyl-4-(4-nitroanilino)-4-oxobutanoic acid cid_2909709 3-benzyl-4-[(4-nitrophenyl)amino]-4-oxobutanoic acid 3-benzyl-4-keto-4-(4-nitroanilino)butyric acid
BDBM63485 4-(4-bromophenyl)-4-oxo-N-(3-pyridinyl)butanamide MLS000665900 4-(4-bromophenyl)-4-oxidanylidene-N-pyridin-3-yl-butanamide SMR000294591 4-(4-bromophenyl)-4-oxo-N-3-pyridinylbutanamide cid_972181 4-(4-bromophenyl)-4-oxo-N-pyridin-3-ylbutanamide 4-(4-bromophenyl)-4-keto-N-(3-pyridyl)butyramide
BDBM86161 CAS_147510-59-6 BE4444 BE 4-4-4-4
US10590139, Example 4 BDBM200576 US9227975, 4 US10011604, 4 US9795611, 4
US9255087, 4 US9029356, 4 BDBM158155 US10081622, Compound 4 US9616059, 4
4-(4-(4-(4-(dimethylamino)phenyl)-4-oxobutoxy)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide CHEMBL1770707 BDBM50343059
4-(4-Chloro-phenyl)-1-[4-(4-methoxy-phenyl)-4-phenyl-butyl]-piperidin-4-ol CHEMBL198111 BDBM50027220
BDBM50343060 CHEMBL1770708 4-(4-(4-(4-(dimethylamino)phenylamino)-4-oxobutoxy)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide
CHEMBL198614 4-(4-Chloro-phenyl)-1-[4-(4-chloro-phenyl)-4-phenyl-butyl]-piperidin-4-ol BDBM50027199
CHEMBL369983 4-(4-(4-carbamoylphenyl)phthalazin-1-ylamino)benzamide 4-[4-(4-carbamoylanilino)-1-phthalazinyl]benzamide BDBM50173042
N-hydroxy-4-(4-(4-(4-methoxyphenylamino)-4-oxobutoxy)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide BDBM50343061 CHEMBL1770157
MLS001030882 SMR000635051 N-[[4-[[4-(4-methoxyphenyl)-1-piperazinyl]-oxomethyl]phenyl]methyl]-4-methylbenzenesulfonamide N-[4-[4-(4-methoxyphenyl)piperazine-1-carbonyl]benzyl]-4-methyl-benzenesulfonamide N-[[4-[4-(4-methoxyphenyl)piperazine-1-carbonyl]phenyl]methyl]-4-methylbenzenesulfonamide N-[[4-[4-(4-methoxyphenyl)piperazin-1-yl]carbonylphenyl]methyl]-4-methyl-benzenesulfonamide BDBM54474 cid_20968605
4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol SB-202190 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole 4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol SB202190 BDBM13531 biotinylated SB202190
SMR000039709 (4-morpholin-4-yl-4-oxidanylidene-butyl) benzoate benzoic acid (4-keto-4-morpholino-butyl) ester cid_658750 benzoic acid [4-(4-morpholinyl)-4-oxobutyl] ester MLS000038593 (4-morpholin-4-yl-4-oxobutyl) benzoate BDBM56003
4-[4-(4-chlorophenyl)thiazol-2-yl]morpholine 4-[4-(4-chlorophenyl)-2-thiazolyl]morpholine BDBM32924 cid_1490732 MLS000695989 4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]morpholine SMR000334892
4-[4-[(4-methyl-1-piperidinyl)sulfonyl]anilino]-4-oxobutanoic acid ethyl ester SMR000123099 BDBM55358 MLS000035466 cid_2139631 4-keto-4-[4-(4-methylpiperidino)sulfonylanilino]butyric acid ethyl ester N-[4-(4-Methyl-piperidine-1-sulfonyl)-phenyl]-succinamic acid ethyl ester ethyl 4-[[4-(4-methylpiperidin-1-yl)sulfonylphenyl]amino]-4-oxidanylidene-butanoate ethyl 4-[4-(4-methylpiperidin-1-yl)sulfonylanilino]-4-oxobutanoate
US9144538, 4-Phenylimidazole BDBM24656 4-phenyl-1H-imidazole 4-PIM 4-phenylimidazole, 4-PI 4-Phenylimidazole US9138393, 4-Phenyl- imidazole CHEMBL14145
4-[(4-methoxyphenyl)amino]-3-[(4-methoxyphenyl)methyl]-4-oxidanylidene-butanoic acid MLS000084871 3-(4-methoxybenzyl)-4-[(4-methoxyphenyl)amino]-4-oxobutanoic acid 4-(4-methoxyanilino)-3-[(4-methoxyphenyl)methyl]-4-oxobutanoic acid 4-keto-4-(p-anisidino)-3-p-anisyl-butyric acid BDBM59665 SMR000019217 cid_3239297
US9926330, 4-4 BDBM380587 N-(trans-4-morpholin-4- ylcyclohexyl)-6- propylquinazolin-4-amine
4-(4-chlorophenyl)-N-[3-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-oxidanylidene-butanamide cid_3595670 4-(4-chlorophenyl)-N-[3-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-oxobutanamide 4-(4-chlorophenyl)-4-keto-N-[3-[(4-methoxyphenyl)sulfamoyl]phenyl]butyramide BDBM57675 SMR000243849 MLS000393398
4-(4-methylpiperidino)-2-(4-pyridyl)quinazoline 4-(4-methylpiperidin-1-yl)-2-pyridin-4-yl-quinazoline SMR000105936 cid_710947 4-(4-methylpiperidin-1-yl)-2-pyridin-4-ylquinazoline BDBM37942 MLS000110003 4-(4-methyl-1-piperidinyl)-2-pyridin-4-ylquinazoline
4-[2-(4-cyanoanilino)-1,3-thiazol-4-yl]benzonitrile BDBM47008 4-[2-(4-cyanoanilino)thiazol-4-yl]benzonitrile 4-[2-[(4-cyanophenyl)amino]-1,3-thiazol-4-yl]benzenecarbonitrile cid_25110138 4-[2-(4-cyanoanilino)-4-thiazolyl]benzonitrile SR-03000000228-1
4-[4-(4-hydroxyphenyl)piperazin-1-yl]-3-nitro-benzamide BDBM58998 SMR000247936 4-[4-(4-hydroxyphenyl)piperazin-1-yl]-3-nitrobenzamide MLS000393797 4-[4-(4-hydroxyphenyl)-1-piperazinyl]-3-nitrobenzamide cid_3275152 4-[4-(4-hydroxyphenyl)piperazino]-3-nitro-benzamide
4-chloro-N-[[1-(4-morpholinosulfonylphenyl)-4-piperidyl]methyl]benzamide 4-chloranyl-N-[[1-(4-morpholin-4-ylsulfonylphenyl)piperidin-4-yl]methyl]benzamide BDBM77132 MLS000067677 cid_3232214 4-chloro-N-[[1-(4-morpholin-4-ylsulfonylphenyl)piperidin-4-yl]methyl]benzamide 4-Chloro-N-{1-[4-(morpholine-4-sulfonyl)-phenyl]-piperidin-4-ylmethyl}-benzamide SMR000125092 4-chloro-N-[[1-[4-(4-morpholinylsulfonyl)phenyl]-4-piperidinyl]methyl]benzamide
4-morpholino-3-nitro-N-[4-(4-pyridylmethyl)phenyl]benzamide 4-(4-morpholinyl)-3-nitro-N-[4-(4-pyridinylmethyl)phenyl]benzamide cid_2983335 BDBM44230 MLS000679974 4-morpholin-4-yl-3-nitro-N-[4-(pyridin-4-ylmethyl)phenyl]benzamide 4-(4-morpholinyl)-3-nitro-N-[4-(pyridin-4-ylmethyl)phenyl]benzamide SMR000296866
N-[4-(4-ethanoylpiperazin-1-yl)phenyl]-4-propoxy-benzamide MLS000071023 N-[4-(4-Acetyl-piperazin-1-yl)-phenyl]-4-propoxy-benzamide SMR000014281 N-[4-(4-acetyl-1-piperazinyl)phenyl]-4-propoxybenzamide N-[4-(4-acetylpiperazino)phenyl]-4-propoxy-benzamide cid_654914 N-[4-(4-acetylpiperazin-1-yl)phenyl]-4-propoxybenzamide BDBM44574
SMR000168958 4-[(4-chlorophenyl)sulfanylmethyl]-1-(phenylsulfonyl)piperidin-4-ol 4-{[(4-chlorophenyl)sulfanyl]methyl}-1-(phenylsulfonyl)-4-piperidinol 1-(benzenesulfonyl)-4-[(4-chlorophenyl)sulfanylmethyl]piperidin-4-ol 1-(benzenesulfonyl)-4-[[(4-chlorophenyl)thio]methyl]-4-piperidinol MLS000549375 cid_4202821 1-besyl-4-[[(4-chlorophenyl)thio]methyl]piperidin-4-ol BDBM52388
3-[4-[4-(4-chlorophenyl)-1-piperazinyl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one BDBM42003 AS-906-25b 3-[4-[4-(4-chlorophenyl)piperazin-1-yl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-[4-(4-chlorophenyl)piperazin-1-yl]-4-oxidanylidene-butyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-[4-(4-chlorophenyl)piperazino]-4-keto-butyl]-2-thioxo-1H-quinazolin-4-one cid_24178251
4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2(3H)-ylidene)cyclohexa-2,5-dienone 4-[5-(4-fluorophenyl)-4-pyridin-4-yl-1H-imidazol-2-yl]phenol BDBM50104383 SB-202190 4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]-phenol 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole CHEMBL278041 4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)phenol
AS-906-25a 3-[4-keto-4-[4-(4-methoxyphenyl)piperazino]butyl]-2-thioxo-1H-quinazolin-4-one 3-[4-[4-(4-methoxyphenyl)piperazin-1-yl]-4-oxidanylidene-butyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-[4-(4-methoxyphenyl)piperazin-1-yl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-[4-(4-methoxyphenyl)-1-piperazinyl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one cid_24178250 BDBM42002
N-[3-cyano-4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-4-methoxybenzamide N-{3-cyano-4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl}-4-methoxybenzamide MLS000047599 N-[3-cyano-4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-4-methoxy-benzamide cid_3241486 N-[3-cyano-4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-4-methoxybenzamide N-[3-cyano-4-[4-(4-methoxyphenyl)piperazino]phenyl]-4-methoxy-benzamide SMR000033610 BDBM32782
BDBM50128643 CHEMBL78478 1-(4-methoxybenzyl)-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide 4-(4-Butoxy-benzenesulfonyl)-1-(4-methoxy-benzyl)-piperidine-4-carboxylic acid hydroxyamide
CHEMBL80401 BDBM50128633 1-(4-fluorobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide 4-(4-Butoxy-benzenesulfonyl)-1-(4-fluoro-benzyl)-piperidine-4-carboxylic acid hydroxyamide
BDBM54466 4-methyl-N-[[4-[[4-(4-nitrophenyl)-1-piperazinyl]-oxomethyl]phenyl]methyl]benzenesulfonamide 4-methyl-N-[4-[4-(4-nitrophenyl)piperazine-1-carbonyl]benzyl]benzenesulfonamide 4-methyl-N-[[4-[4-(4-nitrophenyl)piperazine-1-carbonyl]phenyl]methyl]benzenesulfonamide SMR000622658 cid_16001253 4-methyl-N-[[4-[4-(4-nitrophenyl)piperazin-1-yl]carbonylphenyl]methyl]benzenesulfonamide MLS000912752
4'-(4-Nitrobenzensulfonamide)-4-hydroxychalcone CHEMBL1087324 BDBM50316855
BDBM145651 US9089569, 4 US8952177, 4 US9695149, 4
BDBM158076 US9655879, 4 US9227949, 4 US9024044, 4
BDBM23435 4-methoxybenzoate, 4 CHEMBL1762657 4-methoxybenzoate
BDBM50316854 CHEMBL1087323 4'-(4-Hydroxylbenzensulfonamide)-4-hydroxychalcone
BDBM58292 4-[4-(4-hydroxyphenoxy)phenoxy]phenol
CHEMBL1087448 BDBM50316857 4'-(4-Fluorobenzensulfonamide)-4-hydroxychalcone
CHEMBL1087578 BDBM50316856 4'-(4-Aminobenzensulfonamide)-4-hydroxychalcone
US10053462, 4 BDBM174773 US9540388, 4 US9102686, 4
US8889870, 4 US9388176, 4 BDBM139544 US9820989, 4
CHEMBL78255 1-(4-Bromo-benzyl)-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide BDBM50128669 1-(4-bromobenzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide 4-(4-but-2-ynyloxyphenylsulfanyl)piperidine-4-carboxylic acid hydroxyamide
BDBM50064946 CHEMBL1036 4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol Hydroxyhaloperidol
CHEMBL129159 BDBM50036738 (R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol
CHEMBL129237 BDBM50036734 (S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol
cid_45280883 MLS002699557 4-[4-(4-nitrobenzyl)oxybenzyl]morpholine SMR001563470 4-[[4-[(4-nitrophenyl)methoxy]phenyl]methyl]morpholine BDBM97329
BDBM50343509 SB-203580 4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine 4-(5-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-2,3-dihydro-1H-imidazol-4-yl)pyridine 4-[5-(3-Fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3H-imidazol-4-yl]-pyridine 4-(5-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-4-yl)pyridine 4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-1H-imidazol-4-yl]-pyridine 4-(2-(4-(methylsulfinyl)phenyl)-4-phenyl-1H-imidazol-5-yl)pyridine 4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3H-imidazol-4-yl]-pyridine CHEMBL10 4-[5-(4-Fluoro-phenyl)-2-(4-methylsulfoxide-phenyl)-3H-imidazol-4-yl]-pyridine 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine
1-(3-bromobenzyl)-4-(4-bromophenyl)piperidin-4-ol 4-(4-bromophenyl)-1-[(3-bromophenyl)methyl]piperidin-4-ol MLS000974554 SMR000496447 1-(3-bromobenzyl)-4-(4-bromophenyl)-4-piperidinol 4-(4-bromophenyl)-1-[(3-bromophenyl)methyl]-4-piperidinol BDBM63954 cid_1070039
1-(4-methoxyphenyl)-2-(4-methylmorpholin-4-ium-4-yl)ethanone;iodide BDBM34663 MLS000525902 4-[2-(4-Methoxy-phenyl)-2-oxo-ethyl]-4-methyl-morpholin-4-ium cid_9549493 1-(4-methoxyphenyl)-2-(4-methyl-4-morpholin-4-iumyl)ethanone;iodide SMR000116376
1-[4-(4-chlorophenyl)sulfonylpiperazino]-4-(4-ethoxyphenoxy)butan-1-one SMR000707584 cid_24983035 1-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]-4-(4-ethoxyphenoxy)butan-1-one BDBM80639 1-[4-(4-chlorophenyl)sulfonyl-1-piperazinyl]-4-(4-ethoxyphenoxy)-1-butanone MLS001159634
3-(4-phenylbenzoyl)propionic acid CHEMBL277522 4-(4-biphenylyl)-4-oxobutyric acid 3-(4-biphenylylcarbonyl)propionic acid 4-[1,1'-biphenyl-4-yl]-4-oxobutanoic acid BDBM50240374 Fenbufen gamma-oxo(1,1'-biphenyl)-4-butanoic acid 4-biphenyl-4-yl-4-oxobutanoic acid
4-hydroxybenzoic acid [4-[[(4-hydroxyphenyl)-oxomethoxy]methyl]phenyl]methyl ester BDBM58450 SMR000588531 [4-[(4-hydroxyphenyl)carbonyloxymethyl]phenyl]methyl 4-oxidanylbenzoate [4-[(4-hydroxybenzoyl)oxymethyl]phenyl]methyl 4-hydroxybenzoate cid_2364550 MLS001176159 4-hydroxybenzoic acid [4-[(4-hydroxybenzoyl)oxymethyl]benzyl] ester
BDBM69835 N-(4-methoxyphenyl)-2-pyridin-4-ylquinazolin-4-amine MLS001197232 N-(4-methoxyphenyl)-2-pyridin-4-yl-quinazolin-4-amine SMR000555451 (4-methoxyphenyl)-[2-(4-pyridyl)quinazolin-4-yl]amine N-(4-methoxyphenyl)-2-pyridin-4-yl-4-quinazolinamine cid_877998
MLS000755400 4-[4-(4-chlorophenyl)-2-thiazolyl]benzoic acid cid_1473793 SMR000337797 BDBM49937 4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]benzenecarboxylic acid 4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]benzoic acid 4-[4-(4-chlorophenyl)thiazol-2-yl]benzoic acid
MLS001178632 BDBM93866 2-chloro-4-[4-(4-chlorophenyl)piperazin-1-yl]pyrimidine 2-chloro-4-[4-(4-chlorophenyl)-1-piperazinyl]pyrimidine 2-chloranyl-4-[4-(4-chlorophenyl)piperazin-1-yl]pyrimidine SMR000476419 2-chloro-4-[4-(4-chlorophenyl)piperazino]pyrimidine cid_1713612
N-(4-chlorobenzyl)-4-(4-nitrophenyl)-1-piperazinecarbothioamide SMR000294561 BDBM89320 cid_2957852 MLS000665884 N-(4-chlorobenzyl)-4-(4-nitrophenyl)piperazine-1-carbothioamide N-[(4-chlorophenyl)methyl]-4-(4-nitrophenyl)-1-piperazinecarbothioamide N-[(4-chlorophenyl)methyl]-4-(4-nitrophenyl)piperazine-1-carbothioamide
N-[4-(4-methyl-1-piperazinyl)phenyl]-4-phenoxybenzamide MLS001193363 N-[4-(4-methylpiperazin-1-yl)phenyl]-4-phenoxy-benzamide cid_9118762 N-[4-(4-methylpiperazin-1-yl)phenyl]-4-phenoxybenzamide N-[4-(4-methylpiperazino)phenyl]-4-phenoxy-benzamide SMR000591962 BDBM93897
PD-169316 4-[5-(4-Fluoro-phenyl)-2-(4-nitro-phenyl)-3H-imidazol-4-yl]-pyridine CHEMBL17331 4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl)pyridine BDBM50230001 4-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
SMR000071966 2-(4-fluoroanilino)-4-oxo-4-phenylbutanoic acid 2-[(4-fluorophenyl)amino]-4-oxidanylidene-4-phenyl-butanoic acid BDBM49270 cid_2932695 2-(4-fluoroanilino)-4-keto-4-phenyl-butyric acid MLS000088817 2-[(4-fluorophenyl)amino]-4-oxo-4-phenylbutanoic acid
CHEMBL363548 1-(4-Chloro-phenyl)-4-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-butan-1-one BDBM50219049 1-(4-chlorophenyl)-4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)butan-1-one
MLS000099678 [4-(phenylcarbonyloxy)phenyl] morpholine-4-carboxylate BDBM76360 cid_975181 4-(benzoyloxy)phenyl 4-morpholinecarboxylate (4-benzoyloxyphenyl) morpholine-4-carboxylate 4-morpholinecarboxylic acid (4-benzoyloxyphenyl) ester morpholine-4-carboxylic acid (4-benzoyloxyphenyl) ester SMR000074549
MLS001034005 SMR000385828 4-(morpholinomethyl)-N-[4-(p-phenetylcarbamoyl)phenyl]benzamide N-[4-[(4-ethoxyphenyl)carbamoyl]phenyl]-4-(morpholin-4-ylmethyl)benzamide cid_2115167 N-[4-[(4-ethoxyanilino)-oxomethyl]phenyl]-4-(4-morpholinylmethyl)benzamide BDBM61208
2-(4-methoxyphenoxy)-N-[4-(4-morpholinylsulfonyl)phenyl]acetamide 2-(4-methoxyphenoxy)-N-(4-morpholinosulfonylphenyl)acetamide 2-(4-methoxyphenoxy)-N-(4-morpholin-4-ylsulfonylphenyl)acetamide 2-(4-Methoxy-phenoxy)-N-[4-(morpholine-4-sulfonyl)-phenyl]-acetamide BDBM73224 cid_646975 SMR000013843 2-(4-methoxyphenoxy)-N-(4-morpholin-4-ylsulfonylphenyl)ethanamide MLS000033734
4-(4-hydroxy-benzylideneamino)-benzenesulfonamide 4-(4-hydroxybenzylideneamino)benzenesulfonamide CHEMBL270670 BDBM50229571
4-Nitrobenzyl 4-(4-iodophenyl)piperidine-4-carboxylate oxalate CHEMBL1289855 BDBM50331535
BDBM50494949 4-((4-Hydroxyphenyl)Diazenyl)Benzenesulfonamide CHEMBL379206 4-(4''-Hydroxyphenyl)Diazenylbenzenesulfonamide
CHEMBL1289854 4-Methoxylbenzyl 4-(4-iodophenyl)piperidine-4-carboxylate oxalate BDBM50331534
US10245267, Example 4 US9694016, 4 BDBM202659 US10709712, Example 4 US9242969, 4
US10478423, Cpd. 4 US9408850, 4 US10028934, Compound 4 US9597317, 4 BDBM239015
US9802939, 4 BDBM142857 US11136327, Example 4 US10487086, Example 4 US8940720, 4
US9845333, 4 US10183953, Example 4 BDBM143745 US8969352, 4 US9611277, Example 4
PDDP-G5 CID44294491 BDBM50022235 4-(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-ethynyl-amino]-benzoylamino}-4-carboxy-butyrylamino)-4-carboxy-butyrylamino]-4-carboxy-butyrylamino}-4-carboxy-butyrylamino)-4-carboxy-butyric acid anion
4-chloro-N-(4-{[(2E)-2-(pyridin-4-ylmethylene)hydrazino]carbonyl}phenyl)benzamide BDBM61705 SMR000304930 4-[(4-chlorobenzoyl)amino]-N-(4-pyridylmethyleneamino)benzamide 4-[[(4-chlorophenyl)-oxomethyl]amino]-N-(pyridin-4-ylmethylideneamino)benzamide 4-[(4-chlorobenzoyl)amino]-N-(pyridin-4-ylmethylideneamino)benzamide 4-[(4-chlorophenyl)carbonylamino]-N-(pyridin-4-ylmethylideneamino)benzamide cid_16195509 MLS000722935
BDBM78356 4-[methyl-[4-[(4-nitrophenyl)diazenyl]phenyl]amino]butanoic acid 4-[N-methyl-4-[(4-nitrophenyl)diazenyl]anilino]butanoic acid 4-[4-({4-nitrophenyl}diazenyl)(methyl)anilino]butanoic acid SMR000475642 cid_4162554 4-[N-methyl-4-(4-nitrophenyl)azoanilino]butanoic acid 4-[N-methyl-4-(4-nitrophenyl)azo-anilino]butyric acid MLS001178741
MLS000519824 [4-(4-fluorophenyl)-1-piperazinyl]-[1-(4-methoxyanilino)-4-isoquinolinyl]methanone cid_9550319 BDBM79431 [4-(4-fluorophenyl)piperazin-1-yl]-[1-(4-methoxyanilino)isoquinolin-4-yl]methanone [4-(4-fluorophenyl)piperazin-1-yl]-[1-[(4-methoxyphenyl)amino]isoquinolin-4-yl]methanone [4-(4-fluorophenyl)piperazino]-[1-(p-anisidino)-4-isoquinolyl]methanone SMR000130242
MLS000763592 4-chloro-N-[2-(4-pyridyl)pyrimidin-4-yl]benzamide 4-chloro-N-(2-pyridin-4-ylpyrimidin-4-yl)benzamide 4-chloranyl-N-(2-pyridin-4-ylpyrimidin-4-yl)benzamide 4-chloro-N-(2-pyridin-4-yl-4-pyrimidinyl)benzamide SMR000337180 4-chloro-N-[2-(4-pyridinyl)-4-pyrimidinyl]benzenecarboxamide cid_1488503 BDBM75028
MLS001163287 (2-ethoxy-4-morpholin-4-ylcarbothioyl-phenyl) 4-methoxybenzenesulfonate 2-ethoxy-4-(4-morpholinylcarbonothioyl)phenyl 4-methoxybenzenesulfonate [2-ethoxy-4-(morpholine-4-carbothioyl)phenyl] 4-methoxybenzenesulfonate BDBM63953 cid_2271797 4-methoxybenzenesulfonic acid [2-ethoxy-4-[4-morpholinyl(sulfanylidene)methyl]phenyl] ester 4-methoxybenzenesulfonic acid [2-ethoxy-4-(morpholine-4-carbothioyl)phenyl] ester SMR000497188
N-(4-fluorophenyl)-2-pyridin-4-ylquinazolin-4-amine N-(4-fluorophenyl)-2-pyridin-4-yl-quinazolin-4-amine cid_921587 MLS000589398 (4-Fluoro-phenyl)-(2-pyridin-4-yl-quinazolin-4-yl)-amine SMR000212819 N-(4-fluorophenyl)-2-pyridin-4-yl-4-quinazolinamine BDBM68980 (4-fluorophenyl)-[2-(4-pyridyl)quinazolin-4-yl]amine
1-(4-Fluoro-benzyl)-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide BDBM50128655 1-(4-fluorobenzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide CHEMBL309416
4-morpholinecarboxylic acid (4-phenylphenyl) ester 4-biphenylyl 4-morpholinecarboxylate SMR000069439 MLS000058870 morpholine-4-carboxylic acid (4-phenylphenyl) ester cid_1378785 BDBM84366 (4-phenylphenyl) morpholine-4-carboxylate
BDBM50022234 4-[4-(4-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-ethynyl-amino]-benzoylamino}-4-carboxy-butyrylamino)-4-carboxy-butyrylamino]-4-carboxy-butyric acid anion
BDBM50128632 4-(4-Methoxy-benzenesulfonyl)-1-(4-methoxy-benzyl)-piperidine-4-carboxylic acid hydroxyamide CHEMBL76856 1-(4-methoxybenzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide
BDBM50128651 4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid hydroxyamide 4-(4-(4-chlorophenoxy)phenylsulfonyl)-1-ethyl-N-hydroxypiperidine-4-carboxamide CHEMBL78549
BDBM82668 MLS000563410 SMR000174102 4-Methyl-4-[2-(4-nitro-phenoxy)-ethyl]-morpholin-4-ium 4-methyl-4-[2-(4-nitrophenoxy)ethyl]morpholin-4-ium;iodide cid_11957320
CHEMBL311357 1-butyl-4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide 1-Butyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid hydroxyamide BDBM50128668
CHEMBL78337 BDBM50128674 4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-methyl-piperidine-4-carboxylic acid hydroxyamide 4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxy-1-methylpiperidine-4-carboxamide
CHEMBL79433 BDBM50128648 1-benzyl-4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide 1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid hydroxyamide
2-[(4-chloranylphenoxy)methyl]-5-[4-(4-methoxyphenyl)piperazin-1-yl]-1,3-oxazole-4-carbonitrile MLS000036993 SMR000037619 BDBM44602 cid_662366 2-[(4-chlorophenoxy)methyl]-5-[4-(4-methoxyphenyl)piperazino]oxazole-4-carbonitrile 2-[(4-chlorophenoxy)methyl]-5-[4-(4-methoxyphenyl)-1-piperazinyl]-4-oxazolecarbonitrile 2-[(4-chlorophenoxy)methyl]-5-[4-(4-methoxyphenyl)piperazin-1-yl]-1,3-oxazole-4-carbonitrile
2-[4-(2-methyl-4-quinolyl)piperazino]-4-(4-nitrophenyl)thiazole 2-methyl-4-{4-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]piperazin-1-yl}quinoline cid_1520389 2-[4-(2-methylquinolin-4-yl)piperazin-1-yl]-4-(4-nitrophenyl)-1,3-thiazole MLS000728914 2-[4-(2-methyl-4-quinolinyl)-1-piperazinyl]-4-(4-nitrophenyl)thiazole SMR000307192 BDBM95029
4-[4-[4-(4-methylpiperazin-1-yl)sulfonyl-2-nitro-phenyl]piperazin-1-yl]phenol BDBM59081 cid_16284861 4-[4-[4-[(4-methyl-1-piperazinyl)sulfonyl]-2-nitrophenyl]-1-piperazinyl]phenol MLS001161446 SMR000713508 4-[4-[4-(4-methylpiperazin-1-yl)sulfonyl-2-nitrophenyl]piperazin-1-yl]phenol 4-[4-[4-(4-methylpiperazino)sulfonyl-2-nitro-phenyl]piperazino]phenol
BDBM50114690 CHEMBL111456 4-(2-(4-(methylsulfinyl)benzylthio)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridine 4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfinyl-benzylsulfanyl)-3H-imidazol-4-yl]-pyridine 4-[5-(4-fluorophenyl)-2-(4-methanesulfinyl-benzylsulfanyl)-3H-imidazol-4-yl]pyridine ML-3163 4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfinyl-benzylsulfanyl)-1H-imidazol-4-yl]-pyridine
MLS000526970 BDBM34669 cid_9549540 1-[4-(3-methylbutoxy)phenyl]-2-(4-methylmorpholin-4-ium-4-yl)ethanone;iodide 1-(4-isoamoxyphenyl)-2-(4-methylmorpholin-4-ium-4-yl)ethanone;iodide 1-[4-(3-methylbutoxy)phenyl]-2-(4-methyl-4-morpholin-4-iumyl)ethanone;iodide 4-Methyl-4-{2-[4-(3-methyl-butoxy)-phenyl]-2-oxo-ethyl}-morpholin-4-ium SMR000117444
4-(5-(4-fluorophenyl)-3-isopropylisoxazol-4-yl)pyridine 4-[5-(4-fluorophenyl)-3-isopropylisoxazol-4-yl]pyridine 5-(4-fluorophenyl)-3-isopropyl-4-(pyridin-4-yl)isoxazole BDBM50206423 CHEMBL375428
4-[3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl]pyridine 4-(3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl)pyridine BDBM50206421 CHEMBL220227 3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)isoxazole
4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-ethynyl-amino]-benzoylamino}-4-carboxy-butyrylamino)-4-carboxy-butyrylamino]-4-carboxy-butyrylamino}-4-carboxy-butyric acid anion BDBM50022231
BDBM314100 US9725441, Example 4 US9611221, Example 4 3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic acid US11639333, Example 4 US11214542, Example 4 US9828343, Example 4 US10179769, Example 4 US10807956, Example 4
MLS000061014 SMR000069779 4-[4-(4-chloro-2,6-dimethylphenoxy)butyl]morpholine 4-[4-(4-chloranyl-2,6-dimethyl-phenoxy)butyl]morpholine cid_2248084 4-[4-(4-chloro-2,6-dimethyl-phenoxy)butyl]morpholine BDBM40065
MLS001165246 2-(4-fluorophenyl)-4-keto-4-(3-methoxyphenyl)butyronitrile 2-(4-fluorophenyl)-4-(3-methoxyphenyl)-4-oxobutanenitrile 2-(4-fluorophenyl)-4-(3-methoxyphenyl)-4-oxidanylidene-butanenitrile BDBM69784 cid_5154128 SMR000549701
4-(4-Chloro-phenyl)-1-(4-hydroxy-4-phenyl-butyl)-piperidin-4-ol BDBM50027206 CHEMBL372756
BDBM118351 US9586962, Example 4 US11667644, Example 4 US8653263, 4 US11059828, Example 4 USRE48841, Example 4
BDBM164805 US9688629, 4 US9920031, Example 4 US9802915, Example 4 US11623921, Example 4 US10604504, Example 4
BDBM50335605 (+/-)-4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butyl4-phenylbutanoate CHEMBL1649601
US8791123, 4 US9796724, Example 4 BDBM127631 US10251889, Example 4 US10758542, Example 4 US9782415, Example 4
US9051270, 4 US10087143, Compound 4 US10738009, Compound 4 US9758483, Compound 4 BDBM161219 US11673864, Compound 4
2-(4-chloranylphenoxy)-N-[4-(4-morpholin-4-ylsulfonylphenyl)-1,3-thiazol-2-yl]ethanamide 2-(4-chlorophenoxy)-N-[4-(4-morpholinosulfonylphenyl)thiazol-2-yl]acetamide cid_980197 SMR000123271 BDBM54180 2-(4-chlorophenoxy)-N-[4-(4-morpholin-4-ylsulfonylphenyl)-1,3-thiazol-2-yl]acetamide 2-(4-chlorophenoxy)-N-[4-[4-(4-morpholinylsulfonyl)phenyl]-2-thiazolyl]acetamide MLS000523293 2-(4-Chloro-phenoxy)-N-{4-[4-(morpholine-4-sulfonyl)-phenyl]-thiazol-2-yl}-acetamide
SB-13 BDBM50173647 CHEMBL381642 4-N-methylamino-4'-hydroxystilbene 4-(4-(methylamino)styryl)phenol 4-[(E)-2-(4-Methylamino-phenyl)-vinyl]-phenol [3H]-4-(4-(methylamino)styryl)phenol (E)-4-(4-(methylamino)styryl)phenol
(3E)-4-azanyl-4-[4-(4-chlorophenyl)piperazin-1-yl]buta-1,3-diene-1,1,3-tricarbonitrile cid_6376135 SMR000169891 (3E)-4-amino-4-[4-(4-chlorophenyl)piperazino]buta-1,3-diene-1,1,3-tricarbonitrile (3E)-4-amino-4-[4-(4-chlorophenyl)piperazin-1-yl]buta-1,3-diene-1,1,3-tricarbonitrile 4-amino-4-[4-(4-chlorophenyl)piperazino]-1,3-butadiene-1,1,3-tricarbonitrile BDBM73463 (3E)-4-amino-4-[4-(4-chlorophenyl)-1-piperazinyl]buta-1,3-diene-1,1,3-tricarbonitrile MLS000325539
3-[4-(4-bromophenyl)-4-hydroxy-1-piperidinyl]-1-(4-chlorophenyl)pyrrolidine-2,5-dione MLS000686514 cid_2885027 SMR000268176 3-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-chlorophenyl)pyrrolidine-2,5-dione BDBM45286 3-[4-(4-bromophenyl)-4-oxidanyl-piperidin-1-yl]-1-(4-chlorophenyl)pyrrolidine-2,5-dione 3-[4-(4-bromophenyl)-4-hydroxy-1-piperidinyl]-1-(4-chlorophenyl)-2,5-pyrrolidinedione 3-[4-(4-bromophenyl)-4-hydroxy-piperidino]-1-(4-chlorophenyl)pyrrolidine-2,5-quinone
3-[4-oxidanylidene-4-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]-2-sulfanylidene-1H-quinazolin-4-one AS-906-25c BDBM49155 cid_24178252 3-[4-oxo-4-[4-[4-(trifluoromethyl)phenyl]-1-piperazinyl]butyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-oxo-4-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-keto-4-[4-[4-(trifluoromethyl)phenyl]piperazino]butyl]-2-thioxo-1H-quinazolin-4-one
4-(4-tert-butylphenyl)-4-[[[4-[[(4-methyl-1,2,4-triazol-3-yl)thio]methyl]phenyl]-oxomethyl]hydrazinylidene]butanoic acid MLS000402286 4-(4-tert-butylphenyl)-4-[[4-[(4-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]carbonylhydrazinylidene]butanoic acid BDBM34811 4-(4-tert-butylphenyl)-4-[[4-[(4-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]benzoyl]hydrazinylidene]butanoic acid SMR000243029 4-(4-tert-butylphenyl)-4-[[4-[[(4-methyl-1,2,4-triazol-3-yl)thio]methyl]benzoyl]hydrazono]butyric acid cid_4226612
BDBM39101 MLS000045033 N-[4-[4-(4-chlorophenyl)piperazin-1-yl]carbonylphenyl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide N-[4-[4-(4-chlorophenyl)piperazine-1-carbonyl]phenyl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide N-[4-[4-(4-chlorophenyl)piperazine-1-carbonyl]phenyl]-3,5-dimethyl-isoxazole-4-sulfonamide N-(4-{[4-(4-chlorophenyl)piperazin-1-yl]carbonyl}phenyl)-3,5-dimethylisoxazole-4-sulfonamide cid_3237312 N-[4-[[4-(4-chlorophenyl)-1-piperazinyl]-oxomethyl]phenyl]-3,5-dimethyl-4-isoxazolesulfonamide SMR000026637
2-(4-methylphenoxy)-N-[4-(4-morpholinyl)phenyl]acetamide 2-(4-methylphenoxy)-N-(4-morpholinophenyl)acetamide SMR000111845 2-(4-methylphenoxy)-N-(4-morpholin-4-ylphenyl)ethanamide cid_682558 2-(4-methylphenoxy)-N-(4-morpholin-4-ylphenyl)acetamide MLS000107479 BDBM41809
N-(4-morpholin-4-ylphenyl)-4-piperidin-1-ylsulfonyl-benzamide N-(4-morpholinophenyl)-4-piperidinosulfonyl-benzamide SMR000111921 cid_1118039 N-(4-morpholin-4-ylphenyl)-4-piperidin-1-ylsulfonylbenzamide N-[4-(4-morpholinyl)phenyl]-4-(1-piperidinylsulfonyl)benzamide BDBM55342 MLS000107555
SMR000713844 [4-(4-ethoxyphenyl)sulfonyl-1-piperazinyl]-pyridin-4-ylmethanone [4-(4-ethoxyphenyl)sulfonylpiperazin-1-yl]-pyridin-4-ylmethanone (4-p-phenetylsulfonylpiperazino)-(4-pyridyl)methanone cid_2710693 MLS001078995 [4-(4-ethoxyphenyl)sulfonylpiperazin-1-yl]-pyridin-4-yl-methanone BDBM91126
1-(4-bromobenzyl)-4-[4-(4-morpholin-4-ylbut-2-ynyloxy)benzenesulfonyl]piperdine-4-carboxylic acid hydroxyamide BDBM50156728 CHEMBL375318
4-(4-(4-bromophenylamino)phthalazin-1-yl)benzamide 4-[4-(4-Bromo-phenylamino)-phthalazin-1-yl]-benzamide BDBM50173031 CHEMBL197158
4-(4-(4-methoxyphenylamino)phthalazin-1-yl)benzamide 4-[4-(4-Methoxy-phenylamino)-phthalazin-1-yl]-benzamide CHEMBL195917 BDBM50173043
4-[(4-fluorophenyl)methylsulfanyl]quinazoline BDBM93834 MLS000684751 SMR000323266 cid_6710525 4-[(4-fluorobenzyl)thio]quinazoline 4-[(4-fluorophenyl)methylthio]quinazoline
CGP79787 Analog 38 1-(4-chlorophenoxy)-4-(pyridin-4-ylmethyl)phthalazine 1-(4-Chlorophenoxy)-4-(4-pyridylmethyl)phthalazine BDBM4853
CHEMBL171646 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-isothiazole 4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)isothiazole BDBM50240911
CHEMBL194092 BDBM50217581 4-(4-(1-isopropylpiperidin-4-yloxy)benzyl)morpholine 4-[4-(1-Isopropyl-piperidin-4-yloxy)-benzyl]-morpholine
CHEMBL194746 4-(4-(4-chlorophenylamino)phthalazin-1-yl)benzamide 4-[4-(4-Chloro-phenylamino)-phthalazin-1-yl]-benzamide BDBM50173011
N-hydroxy-4-(4-(4-oxo-4-(4-(trifluoromethoxy)phenylamino)butoxy)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide BDBM50343062 CHEMBL1770709
US10030025, Compound 4 BDBM242742 US9422299, 4 US10836768, Cpd no 4 US9987274, Compound 4 US20240199618, Compound 4 US11731974, Compound 4
(E)-4-(4-hydroxyanilino)-4-keto-but-2-enoic acid SMR000369633 (E)-4-[(4-hydroxyphenyl)amino]-4-oxidanylidene-but-2-enoic acid cid_1201178 MLS000760368 (E)-4-(4-hydroxyanilino)-4-oxobut-2-enoic acid (E)-4-(4-hydroxyanilino)-4-oxo-2-butenoic acid BDBM93694
1-[4-[4-[(4-ethylbenzyl)amino]phenyl]piperazino]ethanone MLS000063754 4-(4-acetyl-1-piperazinyl)-N-(4-ethylbenzyl)aniline 1-[4-[4-[(4-ethylphenyl)methylamino]phenyl]piperazin-1-yl]ethanone SMR000075537 1-[4-[4-[(4-ethylphenyl)methylamino]phenyl]-1-piperazinyl]ethanone BDBM32110 cid_918440
2-[(4-methoxyphenoxy)methyl]-5-[4-(4-methoxyphenyl)piperazino]oxazole-4-carbonitrile cid_1080239 2-[(4-methoxyphenoxy)methyl]-5-[4-(4-methoxyphenyl)piperazin-1-yl]-1,3-oxazole-4-carbonitrile SMR000092436 BDBM44715 2-[(4-methoxyphenoxy)methyl]-5-[4-(4-methoxyphenyl)-1-piperazinyl]-4-oxazolecarbonitrile MLS000115278
2-{4-[4-(4-fluorophenyl)-2-pyrimidinyl]phenoxy}acetohydrazide SMR000550120 cid_1490583 2-[4-[4-(4-fluorophenyl)-2-pyrimidinyl]phenoxy]acetohydrazide 2-[4-[4-(4-fluorophenyl)pyrimidin-2-yl]phenoxy]ethanehydrazide BDBM94047 MLS001165593 2-[4-[4-(4-fluorophenyl)pyrimidin-2-yl]phenoxy]acetohydrazide
4-(4-Bromo-phenyl)-2-(diphenyl-phosphinoyl)-4-[(Z)-hydroxyimino]-butyric acid 4-(4-bromophenyl)-2-diphenylphosphoryl-4-hydroxyimino-butanoic acid MLS000778341 BDBM73746 cid_3491892 4-(4-bromophenyl)-2-diphenylphosphoryl-4-hydroximino-butyric acid SMR000415135 4-(4-bromophenyl)-2-diphenylphosphoryl-4-hydroxyiminobutanoic acid
4-[4-(2-chloro-4-nitrophenyl)piperazin-1-yl]phenol 4-[4-(2-chloranyl-4-nitro-phenyl)piperazin-1-yl]phenol 4-[4-(2-chloro-4-nitro-phenyl)piperazino]phenol MLS000374649 4-[4-(2-chloro-4-nitrophenyl)-1-piperazinyl]phenol BDBM33130 cid_5051642 SMR000244264
4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine SB-203580 4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine BDBM13336 cid_176155 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine CHEMBL10 SB203580
5-(4-methoxyphenyl)-4-[4-(4-methoxyphenyl)-1-piperazinyl]thieno[2,3-d]pyrimidine 5-(4-methoxyphenyl)-4-[4-(4-methoxyphenyl)piperazino]thieno[2,3-d]pyrimidine BDBM75282 SMR000688595 MLS001149801 cid_20964553 5-(4-methoxyphenyl)-4-[4-(4-methoxyphenyl)piperazin-1-yl]thieno[2,3-d]pyrimidine
BDBM55876 cid_4532204 4-[(6-nitro-4-quinolyl)amino]-N-[4-(4-pyridylamino)phenyl]benzamide 4-[(6-nitro-4-quinolinyl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide 4-[(6-nitroquinolin-4-yl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide MLS000766132 SMR000528620
[4-(4-methoxyphenyl)piperazin-1-yl]-[4-(phenylsulfanylmethyl)phenyl]methanone 1-(4-methoxyphenyl)-4-{4-[(phenylthio)methyl]benzoyl}piperazine SMR000270406 [4-(4-methoxyphenyl)-1-piperazinyl]-[4-[(phenylthio)methyl]phenyl]methanone MLS000665179 cid_2913534 [4-(4-methoxyphenyl)piperazino]-[4-[(phenylthio)methyl]phenyl]methanone BDBM50331
4-chloro-3-nitro-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide 4-chloro-N-[4-(4-morpholinylsulfonyl)phenyl]-3-nitrobenzamide 4-chloro-N-(4-morpholin-4-ylsulfonylphenyl)-3-nitrobenzamide 4-chloro-N-(4-morpholinosulfonylphenyl)-3-nitro-benzamide BDBM90800 4-chloranyl-N-(4-morpholin-4-ylsulfonylphenyl)-3-nitro-benzamide cid_986079 MLS001179212 SMR000477491
MLS000061256 ethyl 4-[[4-(morpholin-4-ylmethyl)phenyl]carbonylamino]benzoate BDBM46350 SMR000070125 ethyl 4-{[4-(4-morpholinylmethyl)benzoyl]amino}benzoate cid_1257531 4-[[[4-(4-morpholinylmethyl)phenyl]-oxomethyl]amino]benzoic acid ethyl ester 4-[[4-(morpholinomethyl)benzoyl]amino]benzoic acid ethyl ester ethyl 4-[[4-(morpholin-4-ylmethyl)benzoyl]amino]benzoate
N-[4-(4-morpholinylmethyl)phenyl]-4-propan-2-ylbenzamide BDBM93889 SMR000558555 4-isopropyl-N-[4-(morpholinomethyl)phenyl]benzamide cid_755590 N-[4-(morpholin-4-ylmethyl)phenyl]-4-propan-2-ylbenzamide 4-isopropyl-N-[4-(morpholin-4-ylmethyl)phenyl]benzamide N-[4-(morpholin-4-ylmethyl)phenyl]-4-propan-2-yl-benzamide MLS001196048
N-{4-[(acetylamino)sulfonyl]phenyl}-2-(4-ethylphenyl)-4-quinolinecarboxamide N-[4-(acetylsulfamoyl)phenyl]-2-(4-ethylphenyl)quinoline-4-carboxamide N-[4-(ethanoylsulfamoyl)phenyl]-2-(4-ethylphenyl)quinoline-4-carboxamide SMR000186870 BDBM59916 N-[4-(acetylsulfamoyl)phenyl]-2-(4-ethylphenyl)cinchoninamide cid_1358755 MLS000579682 N-[4-(acetylsulfamoyl)phenyl]-2-(4-ethylphenyl)-4-quinolinecarboxamide
methyl 4-[[4-(morpholin-4-ylmethyl)benzoyl]amino]benzoate 4-[[4-(morpholinomethyl)benzoyl]amino]benzoic acid methyl ester SMR000077137 4-[[[4-(4-morpholinylmethyl)phenyl]-oxomethyl]amino]benzoic acid methyl ester cid_2211303 methyl 4-[[4-(morpholin-4-ylmethyl)phenyl]carbonylamino]benzoate BDBM41174 methyl 4-{[4-(4-morpholinylmethyl)benzoyl]amino}benzoate MLS000064549
(4-brosylphenyl)-(4-methylpiperazino)methanone BDBM56833 cid_660055 [4-(4-bromophenyl)sulfonylphenyl]-(4-methyl-1-piperazinyl)methanone [4-(4-bromophenyl)sulfonylphenyl]-(4-methylpiperazin-1-yl)methanone MLS000036244 SMR000041005
4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxyoxane-4-carboxamide alpha-sulfone 21 BDBM11870 4-{[4-(4-Chlorophenoxy)phenyl]sulfonyl}-N-hydroxy tetrahydro-2H-pyran-4-carboxamide
BDBM55347 N-[(4-methylphenyl)methyl]-4-(4-morpholinylmethyl)benzamide MLS000110448 SMR000106378 N-(4-methylbenzyl)-4-(morpholinomethyl)benzamide N-[(4-methylphenyl)methyl]-4-(morpholin-4-ylmethyl)benzamide cid_882525
(4-chlorophenyl)-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]methanone SMR000296226 cid_1251584 BDBM43528 MLS000676065 7-chloro-4-[4-(4-chlorobenzoyl)-1-piperazinyl]quinoline (4-chlorophenyl)-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]methanone (4-chlorophenyl)-[4-(7-chloro-4-quinolyl)piperazino]methanone [4-(7-chloranylquinolin-4-yl)piperazin-1-yl]-(4-chlorophenyl)methanone
1-[4-(4-fluorophenyl)piperazin-1-yl]-4-phenoxy-butan-1-one BDBM77276 SMR000141837 1-(4-fluorophenyl)-4-(4-phenoxybutanoyl)piperazine MLS000534401 cid_2286724 1-[4-(4-fluorophenyl)piperazin-1-yl]-4-phenoxybutan-1-one 1-[4-(4-fluorophenyl)-1-piperazinyl]-4-phenoxy-1-butanone 1-[4-(4-fluorophenyl)piperazino]-4-phenoxy-butan-1-one
4-keto-4-(4-propoxyphenyl)butyric acid [2-keto-2-(p-phenetidino)ethyl] ester SMR000253271 BDBM32869 4-oxo-4-(4-propoxyphenyl)butanoic acid [2-(4-ethoxyanilino)-2-oxoethyl] ester [2-(4-ethoxyanilino)-2-oxoethyl] 4-oxo-4-(4-propoxyphenyl)butanoate cid_3349697 MLS000335517 [2-[(4-ethoxyphenyl)amino]-2-oxidanylidene-ethyl] 4-oxidanylidene-4-(4-propoxyphenyl)butanoate
BDBM74042 1-(4-Chloro-phenyl)-4-(morpholine-4-carbonyl)-pyrrolidin-2-one MLS001223067 cid_217803 SMR000613636 1-(4-chlorophenyl)-4-(morpholine-4-carbonyl)-2-pyrrolidone 1-(4-chlorophenyl)-4-(morpholine-4-carbonyl)pyrrolidin-2-one 1-(4-chlorophenyl)-4-morpholin-4-ylcarbonyl-pyrrolidin-2-one 1-(4-chlorophenyl)-4-[4-morpholinyl(oxo)methyl]-2-pyrrolidinone
BDBM90035 SMR000195829 1-(4-nitrophenyl)-4-(4-phenylbutanoyl)piperazine cid_2907423 1-[4-(4-nitrophenyl)piperazin-1-yl]-4-phenyl-butan-1-one 1-[4-(4-nitrophenyl)piperazin-1-yl]-4-phenylbutan-1-one 1-[4-(4-nitrophenyl)-1-piperazinyl]-4-phenyl-1-butanone MLS000574237 1-[4-(4-nitrophenyl)piperazino]-4-phenyl-butan-1-one
BDBM90089 3-(4-methoxyphenyl)-5-[(4-nitrobenzyl)thio]-4-p-phenetyl-1,2,4-triazole SMR000220863 4-(4-ethoxyphenyl)-3-(4-methoxyphenyl)-5-[(4-nitrophenyl)methylthio]-1,2,4-triazole cid_1424828 MLS000331402 4-(4-Ethoxy-phenyl)-3-(4-methoxy-phenyl)-5-(4-nitro-benzylsulfanyl)-4H-[1,2,4]triazole 4-(4-ethoxyphenyl)-3-(4-methoxyphenyl)-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazole
N-[4-(pyridin-4-ylmethyl)phenyl]-4-pyrrolidin-1-ylsulfonylbenzamide N-[4-(pyridin-4-ylmethyl)phenyl]-4-(1-pyrrolidinylsulfonyl)benzamide MLS000862435 BDBM54308 SMR000301275 N-[4-(pyridin-4-ylmethyl)phenyl]-4-pyrrolidin-1-ylsulfonyl-benzamide N-[4-(pyridin-4-ylmethyl)phenyl]-4-(pyrrolidin-1-ylsulfonyl)benzamide cid_1506472 N-[4-(4-pyridylmethyl)phenyl]-4-pyrrolidinosulfonyl-benzamide
[2-ethoxy-4-(morpholine-4-carbothioyl)phenyl] 4-acetamidobenzenesulfonate cid_1796835 (2-ethoxy-4-morpholin-4-ylcarbothioyl-phenyl) 4-acetamidobenzenesulfonate MLS000538718 4-acetamidobenzenesulfonic acid [2-ethoxy-4-[4-morpholinyl(sulfanylidene)methyl]phenyl] ester 4-acetamidobenzenesulfonic acid [2-ethoxy-4-(morpholine-4-carbothioyl)phenyl] ester BDBM46384 SMR000160965 2-ethoxy-4-(4-morpholinylcarbothioyl)phenyl 4-(acetylamino)benzenesulfonate
cid_653901 N-Cyclopentyl-4-[4-(4-methoxy-phenyl)-piperazine-1-sulfonyl]-benzamide N-cyclopentyl-4-[[4-(4-methoxyphenyl)-1-piperazinyl]sulfonyl]benzamide N-cyclopentyl-4-[4-(4-methoxyphenyl)piperazino]sulfonyl-benzamide BDBM45307 SMR000003936 N-cyclopentyl-4-[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl-benzamide MLS000076110 N-cyclopentyl-4-[4-(4-methoxyphenyl)piperazin-1-yl]sulfonylbenzamide
3-(4-methoxyphenyl)-2-(4-nitrophenyl)thiazolidin-4-one SMR000555044 3-(4-methoxyphenyl)-2-(4-nitrophenyl)-4-thiazolidinone BDBM90878 cid_3754708 MLS001194523 3-(4-methoxyphenyl)-2-(4-nitrophenyl)-1,3-thiazolidin-4-one
4-[4-(4-methyl-2-quinolyl)phenyl]morpholine;hydrochloride 4-[4-(4-methylquinolin-2-yl)phenyl]morpholine;hydrochloride cid_12006251 MLS000417979 SMR000264721 4-[4-(4-methyl-2-quinolinyl)phenyl]morpholine;hydrochloride BDBM51057
MLS001033622 [4-(dimethylamino)phenyl]-[4-(4-nitrophenyl)-1-piperazinyl]methanethione cid_3962495 BDBM32966 [4-(dimethylamino)phenyl]-[4-(4-nitrophenyl)piperazin-1-yl]methanethione SMR000363998 [4-(dimethylamino)phenyl]-[4-(4-nitrophenyl)piperazino]methanethione
MLS000576214 N'-[(4-bromophenyl)-oxomethyl]-4-propylbenzohydrazide BDBM82715 SMR000185241 cid_1377841 N'-(4-bromobenzoyl)-4-propylbenzohydrazide 4-bromo-N'-(4-propylbenzoyl)benzohydrazide N'-(4-bromophenyl)carbonyl-4-propyl-benzohydrazide N'-(4-bromobenzoyl)-4-propyl-benzohydrazide
N'-[(4-chlorophenyl)-oxomethyl]-4-propylbenzohydrazide BDBM82691 SMR000185280 cid_765467 N'-(4-chlorobenzoyl)-4-propyl-benzohydrazide MLS000576608 N'-(4-chlorobenzoyl)-4-propylbenzohydrazide 4-chloro-N'-(4-propylbenzoyl)benzohydrazide N'-(4-chlorophenyl)carbonyl-4-propyl-benzohydrazide
BDBM153162 US8993756, 4-4
BDBM228952 US9328099, 4-4
BDBM257420 US9493441, 4-4
BDBM331002 US9725445, 4-4
US8742110, 4-4 BDBM123240
US8987273, 4-4 BDBM151097
US9145391, 4-4 BDBM182107
US9247759, 4-4 BDBM210970
BDBM103890 US10047086, 4 US9695168, 4 US10640503, Example 4
BDBM10443 4-Aminoquinaldine 4 2-methylquinolin-4-amine
BDBM50312676 CHEMBL1076672 Podpphyllotoxinyl 4-(4-methoxyphenethylamino)-4-oxobutanoate
BDBM77033 US10487111, Example 4. US9694018, 4 US10093697, 4.
US8987249, 4 US9713606, 4 BDBM150330 US10238633, Example 4
US9227969, 4 US9629836, 4 BDBM200376 US10011599, Example 4
US9346797, 4 BDBM230868 US10603310, Compound 4 US10045974, 4
1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide CHEMBL222934 BDBM50156718
1-[4-Chlorophenylcarbonyl]-4-[4-(pyridin-4-yl)phenylmethyl]-piperazine CHEMBL482527 BDBM50271572
4-(4-Fluorophenyl)-4-oxo-3-(pyridin-4-yl)butanal CHEMBL507086 BDBM50256868
4-CPI 5-(4-chlorophenyl)-1H-imidazole 4-(4-chlorophenyl)imidazole BDBM19475
4-[(4-fluorophenyl)methyl]piperidine BDBM15788 fragment 4 CHEMBL144527 CHEMBL1204355 piperidine 4
BDBM251906 US10065961, Compound 4 US10941151, Compound 4 US9475814, 4 US10683295, Compound 4
BDBM254130 US10703749, Example 4 US9464084, 4 US10150765, Example 4 US10112937, Example 4
BDBM259405 US11673868, Example 4 US9512084, 4 US11180460, Example 4 US10457647, Example 4
BDBM50271571 CHEMBL482526 1-[4-Chlorophenylsulfonyl]-4-[4-(pyridin-4-yl)phenylmethyl]-piperazine
BDBM50271574 CHEMBL520786 1-[4-Methoxyphenylcarbonyl]-4-[4-(pyridin-4-yl)phenylmethyl]-piperazine
CHEMBL346267 4-[4-(4-Chloro-phenoxy)-phenyl]-4-oxo-butyric acid BDBM50049241
CHEMBL482528 BDBM50271573 1-[4-Chlorobenzyl]-4-[4-(pyridin-4-yl)phenylmethyl]-piperazine
CHEMBL596803 BDBM50308016 4-[4-(4-Phenylpiperazinilmetil)-1H-1,2,3-triazol-4-yl]acetamide
US10106559, Example 4 BDBM230083 US9334290, 4 US9850258, Example 4 US10435415, Example 4
US10213433, Compound 4 BDBM189458 US9174982, 4 US11369599, Compound 4 US20240043404, Example 4
US8846601, 4 US9458201, 4 US10632171, Peptide No. 4 BDBM135619 US10179804, Example 4
US9314464, 4 US10568884, Cpd 4 BDBM221683 US9593100, Compound 4 USRE49556, Compound 4
US9320732, 4 BDBM223002 US10967060, Example 4 US10034939, Example 4 US11207302, Example 4
US9475795, 4 US11512066, Example 4 US10544126, Example 4 BDBM250525 US10167273, Example 4
US9931340, Example 4 US10463663, Example 4 BDBM210775 US11129828, Example 4 US9290456, 4
4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine BDBM16219 pyrazole-based inhibitor 9
BDBM279666 US11560377, Compound 4 US10035797, Compound 4 US9630965, Compound 4 US10428068, Compound 4 US10844056, Compound 4
BDBM304988 US10881652, Example 4 US10441581, Example 4 US10144734, Example 4 US10172845, Example 4 US11648243, Example 4
BDBM363511 US10689414, Compound 4 US10640534, Compound 4 US10717764, Compound 4 US11021515, Compound 4 US9850277, Compound 4
BDBM50027193 4-(4-Chloro-phenyl)-1-(4-phenyl-4-p-tolyl-butyl)-piperidin-4-ol CHEMBL370577
BDBM50027210 CHEMBL198553 4-(4-Chloro-phenyl)-1-(4-phenyl-4-o-tolyl-butyl)-piperidin-4-ol
BDBM50027215 4-(4-Chloro-phenyl)-1-(4-phenyl-4-m-tolyl-butyl)-piperidin-4-ol CHEMBL383822
CHEMBL1770712 BDBM50343066 N-hydroxy-4-(4-(4-(4-methoxyphenoxy)butoxy)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide
US10239868, Entry 4 US10287274, Entry 4 US20240425487, Entry 4 US9802924, Entry 4 US10676464, Entry 4 BDBM352200
US10343992, Example 4 US11053198, Example 4 US10689345, Example 4 US11066365, Example 4 US11390584, Example 4 BDBM404345
US10793564, Compound 4 US20230293519, Compound 4 US11419869, Compound 4 BDBM465215 US11560376, Compound 4 US20230271960, Compound 4
US11548872, Compound 4 US10544128, Compound 4 US9951048, Compound 4 US10106527, Compound 4 BDBM293418 US20230286945, Compound 4
4-(4-(4-(benzyloxy)phenylamino)phthalazin-1-yl)benzamide BDBM50173028 CHEMBL197357 4-[4-(4-Benzyloxy-phenylamino)-phthalazin-1-yl]-benzamide
4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-piperidine-4-carboxylic acid dimethylamide Amiperone BDBM50133925 CHEMBL341578
4-[4-(4-Trifluoromethoxy-phenoxy)-phthalazin-1-yl]-benzamide 4-(4-(4-(trifluoromethoxy)phenoxy)phthalazin-1-yl)benzamide BDBM50173008 CHEMBL196491
4-{[(4-fluorophenyl)carbamoyl]amino}benzenesulfonamide 4-{[(4'-Fluorophenyl)carbamoyl]amino}benzenesulfonamide 4-(3-(4-fluorophenyl)ureido)benzenesulfonamide CHEMBL1615281 BDBM50334354
BDBM50173050 4-[4-(4-Trifluoromethoxy-phenylsulfanyl)-phthalazin-1-yl]-benzamide CHEMBL196838 4-(4-(4-(trifluoromethoxy)phenylthio)phthalazin-1-yl)benzamide
BDBM50343063 CHEMBL1770697 N-hydroxy-4-(4-(4-(methyl(4-(trifluoromethoxy)phenyl)amino)-4-oxobutoxy)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide
BDBM64162 N-(4-fluorophenyl)-4-nitroaniline (4-fluorophenyl)-(4-nitrophenyl)amine MLS001182007 N-(4-fluorophenyl)-4-nitro-aniline cid_2818275 SMR000567724
CGP79787 Analog 39 1-(4-Chlorophenylsulfanyl)-4-(4-pyridylmethyl)phthalazine 1-[(4-chlorophenyl)sulfanyl]-4-(pyridin-4-ylmethyl)phthalazine BDBM4854
CHEMBL205219 2-{4-[4-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-chromen-4-one BDBM50183248 [4',4''']-biflavone
MLS000058792 cid_786803 4-(4-hydroxyphenyl)carbonylphthalic acid BDBM59371 SMR000069057 4-[(4-hydroxyphenyl)-oxomethyl]phthalic acid 4-(4-hydroxybenzoyl)phthalic acid
Pyridine deriv. 9 4-(4-fluorophenyl)-5-(pyridin-4-yl)-1,3-oxazole BDBM15411 4-[4-(4-Fluorophenyl)-5-oxazolyl]-pyridine
4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}-[1,4']bipiperidinyl CHEMBL420008 BDBM50092957 4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)vinyl)-1-(piperidin-4-yl)piperidine
SMR000103347 (4-chlorophenyl)-(4-morpholinyl)methanethione (4-chlorophenyl)-morpholin-4-yl-methanethione (4-chlorophenyl)-morpholin-4-ylmethanethione MLS000106380 (4-chlorophenyl)-morpholino-methanethione BDBM34554 cid_684261
4-butoxy-N-(4-pyridyl)benzamide MLS000100092 BDBM46349 4-butoxy-N-pyridin-4-ylbenzamide SMR000081849 4-butoxy-N-pyridin-4-yl-benzamide 4-butoxy-N-4-pyridinylbenzamide cid_2232224
CHEMBL80814 1-(4-methoxyphenethyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide BDBM50128638 4-(4-Methoxy-benzenesulfonyl)-1-[2-(4-methoxy-phenyl)-ethyl]-piperidine-4-carboxylic acid hydroxyamide
cid_1122575 4-[(4-methylphenyl)methoxy]benzaldehyde oxime SMR000270506 MLS000663909 4-(4-methylbenzyl)oxybenzaldoxime 4-[(4-methylbenzyl)oxy]benzaldehyde oxime BDBM76512 N-[[4-[(4-methylphenyl)methoxy]phenyl]methylidene]hydroxylamine
2-(4-fluorophenyl)-2-[4-(4-fluorophenyl)carbonylphenyl]ethanenitrile 2-[4-(4-fluorobenzoyl)phenyl]-2-(4-fluorophenyl)acetonitrile cid_2774422 2-(4-fluorophenyl)-2-[4-[(4-fluorophenyl)-oxomethyl]phenyl]acetonitrile SMR000125434 BDBM39653 MLS000539976
4-(2,1,3-benzothiadiazol-4-ylsulfonylamino)-N-[(4-fluorophenyl)methyl]butanamide MLS000047167 cid_3244794 BDBM41249 N-(4-fluorobenzyl)-4-(piazthiol-4-ylsulfonylamino)butyramide 4-[(2,1,3-benzothiadiazol-4-ylsulfonyl)amino]-N-(4-fluorobenzyl)butanamide SMR000033178
MLS002253020 SMR001315349 BDBM94062 2-[4-(4-methylphenoxy)phenoxy]-N-pyridin-4-ylacetamide cid_2318546 2-[4-(4-methylphenoxy)phenoxy]-N-(4-pyridyl)acetamide 2-[4-(4-methylphenoxy)phenoxy]-N-pyridin-4-yl-ethanamide
2-[4-(4-fluorophenyl)carbonylphenyl]-2-(4-methylphenyl)ethanenitrile 2-[4-(4-fluorobenzoyl)phenyl]-2-(4-methylphenyl)acetonitrile 2-[4-(4-fluorobenzoyl)phenyl]-2-(p-tolyl)acetonitrile cid_2774427 MLS000539977 BDBM39666 SMR000125435 2-[4-[(4-fluorophenyl)-oxomethyl]phenyl]-2-(4-methylphenyl)acetonitrile
4-(4-methoxyanilino)-4-oxo-3-(phenylmethyl)butanoic acid 4-[(4-methoxyphenyl)amino]-4-oxidanylidene-3-(phenylmethyl)butanoic acid 3-benzyl-4-(4-methoxyanilino)-4-oxobutanoic acid 3-benzyl-4-keto-4-(p-anisidino)butyric acid SMR000107396 BDBM59767 MLS000111474 cid_3826964
4-[[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]amino]benzonitrile 4-[[4-(4-ethoxyphenyl)-2-thiazolyl]amino]benzonitrile BDBM47009 4-[[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]amino]benzenecarbonitrile SR-03000000230-1 cid_25110139 4-[(4-p-phenetylthiazol-2-yl)amino]benzonitrile
4-nitrobenzoic acid 4-(4-methylphenyl)sulfonylbut-2-ynyl ester 4-nitrobenzoic acid 4-tosylbut-2-ynyl ester SMR000141506 cid_2244013 MLS000534068 4-[(4-methylphenyl)sulfonyl]-2-butyn-1-yl 4-nitrobenzoate 4-(4-methylphenyl)sulfonylbut-2-ynyl 4-nitrobenzoate BDBM66337
BDBM55755 N'-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-nitro-benzohydrazide N'-[2,6-bis(4-morpholinyl)-4-pyrimidinyl]-4-nitrobenzohydrazide SMR000285282 N'-(2,6-dimorpholinopyrimidin-4-yl)-4-nitro-benzohydrazide N'-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-nitrobenzohydrazide cid_3121368 MLS000678325
BDBM83170 4-[[4-(aminocarbonylamino)phenyl]carbonylamino]-N-(4-ethoxyphenyl)benzamide cid_2410168 SMR001315691 N-p-phenetyl-4-[(4-ureidobenzoyl)amino]benzamide 4-[[4-(carbamoylamino)benzoyl]amino]-N-(4-ethoxyphenyl)benzamide MLS002248213 4-[[[4-(carbamoylamino)phenyl]-oxomethyl]amino]-N-(4-ethoxyphenyl)benzamide
MLS000112735 6-bromo-N-[4-(4-morpholinyl)phenyl]-4-quinazolinamine 6-bromo-N-(4-morpholin-4-ylphenyl)quinazolin-4-amine cid_1189450 (6-bromoquinazolin-4-yl)-(4-morpholinophenyl)amine 6-bromanyl-N-(4-morpholin-4-ylphenyl)quinazolin-4-amine SMR000108645 BDBM37255
MLS002154263 4-(4-chlorophenyl)butyl-diethyl-heptyl-azanium;4-methylbenzenesulfonate Clofilium tosylate BDBM89440 4-(4-chlorophenyl)butyl-diethyl-heptylammonium;4-methylbenzenesulfonate CHEMBL9484 cid_175533 SMR001233522 4-(4-chlorophenyl)butyl-diethyl-heptyl-ammonium;tosylate 4-(4-chlorophenyl)butyl-diethyl-heptylazanium;4-methylbenzenesulfonate
SMR000019216 MLS000084870 BDBM59660 cid_3238574 4-anilino-3-[(4-methoxyphenyl)methyl]-4-oxobutanoic acid 3-[(4-methoxyphenyl)methyl]-4-oxidanylidene-4-phenylazanyl-butanoic acid 4-anilino-3-(4-methoxybenzyl)-4-oxobutanoic acid 4-anilino-4-keto-3-p-anisyl-butyric acid
SMR001249295 3-amino-N-(4-methoxyphenyl)-4-(4-morpholinyl)benzenesulfonamide MLS002166959 3-amino-N-(4-methoxyphenyl)-4-morpholin-4-ylbenzenesulfonamide 3-azanyl-N-(4-methoxyphenyl)-4-morpholin-4-yl-benzenesulfonamide BDBM89451 cid_3292313 3-amino-N-(4-methoxyphenyl)-4-morpholino-benzenesulfonamide
(4-Chloro-phenyl)-(4-pyridin-4-yl-thiazol-2-yl)-amine BDBM40156 (4-chlorophenyl)-[4-(4-pyridyl)thiazol-2-yl]amine N-(4-chlorophenyl)-4-pyridin-4-yl-2-thiazolamine MLS000527801 N-(4-chlorophenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine cid_704499 SMR000120375
(4-fluorophenyl)-[4-(4-phenylcyclohexyl)piperazin-1-yl]methanone;oxalic acid BDBM52645 ethanedioic acid;(4-fluorophenyl)-[4-(4-phenylcyclohexyl)piperazin-1-yl]methanone (4-fluorophenyl)-[4-(4-phenylcyclohexyl)piperazino]methanone;oxalic acid MLS000688017 (4-fluorophenyl)-[4-(4-phenylcyclohexyl)-1-piperazinyl]methanone;oxalic acid cid_2880178 SMR000284566
(Z)-4-oxidanylidene-4-[(4-phenylmethoxyphenyl)amino]but-2-enoic acid (Z)-4-(4-benzoxyanilino)-4-keto-but-2-enoic acid (Z)-4-oxo-4-(4-phenylmethoxyanilino)-2-butenoic acid MLS000714786 BDBM63459 (Z)-4-oxo-4-(4-phenylmethoxyanilino)but-2-enoic acid SMR000274765 cid_5760382
1-(4-methoxyphenyl)-3-(4-morpholin-4-ylcarbonylphenyl)urea N-(4-methoxyphenyl)-N'-[4-(4-morpholinylcarbonyl)phenyl]urea BDBM59739 SMR000075524 1-(4-methoxyphenyl)-3-[4-[4-morpholinyl(oxo)methyl]phenyl]urea 1-(4-methoxyphenyl)-3-[4-(morpholine-4-carbonyl)phenyl]urea cid_1288686 MLS000063747
2-(4-methoxyphenyl)-5-methyl-4-[(4-quinazolin-4-ylpiperazino)methyl]oxazole 2-(4-methoxyphenyl)-5-methyl-4-[(4-quinazolin-4-ylpiperazin-1-yl)methyl]-1,3-oxazole 2-(4-methoxyphenyl)-5-methyl-4-[[4-(4-quinazolinyl)-1-piperazinyl]methyl]oxazole BDBM62236 MLS-0412041.0001 cid_25460982
4-ethoxy-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]benzamide 4-ethoxy-N-[4-(4-methylpiperazino)sulfonylphenyl]benzamide cid_4948552 4-ethoxy-N-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}benzamide SMR000498832 4-ethoxy-N-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]benzamide MLS001001075 BDBM73850
BDBM43103 MLS000388833 2-[4-(4-fluorophenyl)carbonylphenoxy]-N-[(4-methylphenyl)methyl]ethanamide 2-[4-(4-fluorobenzoyl)phenoxy]-N-(4-methylbenzyl)acetamide 2-[4-[(4-fluorophenyl)-oxomethyl]phenoxy]-N-[(4-methylphenyl)methyl]acetamide SMR000255006 cid_2564956 2-[4-(4-fluorobenzoyl)phenoxy]-N-[(4-methylphenyl)methyl]acetamide
BDBM43312 N-(4-hydroxynaphthalen-1-yl)-4-(4-methoxyphenyl)benzenesulfonamide cid_16738590 PCMD-CC-MCM-223 N-(4-hydroxy-1-naphthalenyl)-4-(4-methoxyphenyl)benzenesulfonamide N-(4-hydroxy-1-naphthyl)-4-(4-methoxyphenyl)benzenesulfonamide 4-(4-methoxyphenyl)-N-(4-oxidanylnaphthalen-1-yl)benzenesulfonamide PC-0599226
MLS000766850 [4-(4-ethyl-1-piperazinyl)-3-quinolinyl]-(4-methoxyphenyl)methanone [4-(4-ethylpiperazino)-3-quinolyl]-(4-methoxyphenyl)methanone [4-(4-ethylpiperazin-1-yl)quinolin-3-yl](4-methoxyphenyl)methanone BDBM69283 cid_6625000 SMR000339746 [4-(4-ethylpiperazin-1-yl)quinolin-3-yl]-(4-methoxyphenyl)methanone
MLS000923810 cid_4220844 4-[4-(benzenesulfonyl)-2-(4-fluorophenyl)-5-oxazolyl]morpholine 4-[4-(benzenesulfonyl)-2-(4-fluorophenyl)-1,3-oxazol-5-yl]morpholine 4-[4-besyl-2-(4-fluorophenyl)oxazol-5-yl]morpholine 4-[2-(4-fluorophenyl)-4-(phenylsulfonyl)-1,3-oxazol-5-yl]morpholine SMR000620410 BDBM94345
N-[4-[4-(4-methoxyphenyl)piperazin-1-yl]carbonylphenyl]benzenesulfonamide N-[4-[4-(4-methoxyphenyl)piperazine-1-carbonyl]phenyl]benzenesulfonamide cid_2969019 MLS000051496 SMR000079897 BDBM62754 N-[4-[[4-(4-methoxyphenyl)-1-piperazinyl]-oxomethyl]phenyl]benzenesulfonamide N-(4-{[4-(4-methoxyphenyl)-1-piperazinyl]carbonyl}phenyl)benzenesulfonamide
SMR000269268 4-methoxy-N-[[4-(4-nitrophenyl)-1-piperazinyl]-sulfanylidenemethyl]benzamide 4-methoxy-N-[4-(4-nitrophenyl)piperazine-1-carbothioyl]benzamide 4-methoxy-N-{[4-(4-nitrophenyl)-1-piperazinyl]carbonothioyl}benzamide cid_2899211 MLS000681004 BDBM44059 4-methoxy-N-[4-(4-nitrophenyl)piperazin-1-yl]carbothioyl-benzamide
[1-methyl-4-(4-phenyl-1-piperazinyl)-4-piperidinyl]methanamine [1-methyl-4-(4-phenylpiperazin-1-yl)piperidin-4-yl]methylamine [1-methyl-4-(4-phenylpiperazin-1-yl)piperidin-4-yl]methanamine BDBM78991 SMR000559399 MLS001198041 cid_5297747 [1-methyl-4-(4-phenylpiperazino)-4-piperidyl]methylamine
(4-bromophenyl)-[4-(4-methoxy-2-nitro-phenyl)piperazin-1-yl]methanone (4-bromophenyl)-[4-(4-methoxy-2-nitro-phenyl)piperazino]methanone (4-bromophenyl)-[4-(4-methoxy-2-nitrophenyl)-1-piperazinyl]methanone 1-(4-bromobenzoyl)-4-(4-methoxy-2-nitrophenyl)piperazine (4-bromophenyl)-[4-(4-methoxy-2-nitrophenyl)piperazin-1-yl]methanone SMR000296120 cid_2973383 MLS000672486 BDBM66027
1-amino-3-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]urea 1-amino-3-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]urea BDBM63968 SMR000477786 1-amino-3-[4-[4-(4-methoxyphenyl)piperazino]phenyl]urea 1-azanyl-3-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]urea cid_820816 N-{4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl}hydrazinecarboxamide MLS001181013
2-(4-bromophenyl)-N-[4-[(4-methyl-2-pyrimidinyl)sulfamoyl]phenyl]-4-quinolinecarboxamide 2-(4-bromophenyl)-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]quinoline-4-carboxamide cid_1371168 MLS000572245 BDBM57517 2-(4-bromophenyl)-N-(4-{[(4-methyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-4-quinolinecarboxamide 2-(4-bromophenyl)-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]cinchoninamide SMR000194206
2-(4-chlorophenyl)-4-(2,3-dichloro-4-ethylsulfonylphenyl)-1,3-thiazole 2-(4-chlorophenyl)-4-(2,3-dichloro-4-ethylsulfonylphenyl)thiazole 4-[2,3-bis(chloranyl)-4-ethylsulfonyl-phenyl]-2-(4-chlorophenyl)-1,3-thiazole MLS000326830 2-(4-chlorophenyl)-4-(2,3-dichloro-4-esyl-phenyl)thiazole cid_5225192 BDBM61468 SMR000179339 2-(4-chlorophenyl)-4-[2,3-dichloro-4-(ethylsulfonyl)phenyl]-1,3-thiazole
4-chlorobenzoic acid [2,6-dibromo-4-(morpholine-4-carbothioyl)phenyl] ester BDBM47575 MLS000562714 4-chlorobenzoic acid [2,6-dibromo-4-[4-morpholinyl(sulfanylidene)methyl]phenyl] ester cid_1142386 4-Chloro-benzoic acid 2,6-dibromo-4-(morpholine-4-carbothioyl)-phenyl ester SMR000175689 [2,6-bis(bromanyl)-4-morpholin-4-ylcarbothioyl-phenyl] 4-chloranylbenzoate [2,6-dibromo-4-(morpholine-4-carbothioyl)phenyl] 4-chlorobenzoate
BDBM56526 SMR000200300 5-(4-fluorophenyl)-N-[4-(4-morpholinyl)phenyl]-4-thieno[2,3-d]pyrimidinamine [5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]-(4-morpholinophenyl)amine cid_1194679 MLS000581774 5-(4-fluorophenyl)-N-(4-morpholin-4-ylphenyl)thieno[2,3-d]pyrimidin-4-amine 5-(4-fluorophenyl)-N-[4-(4-morpholinyl)phenyl]thieno[2,3-d]pyrimidin-4-amine
MLS000326227 cid_1479463 BDBM77377 4-(4-chlorophenyl)sulfanyl-6-[(4-chlorophenyl)sulfonylmethyl]-2-methyl-pyrimidine 4-[(4-chlorophenyl)sulfonylmethyl]-6-[(4-chlorophenyl)thio]-2-methylpyrimidine 4-[(4-chlorophenyl)sulfonylmethyl]-6-[(4-chlorophenyl)thio]-2-methyl-pyrimidine 4-(4-chlorophenyl)sulfanyl-6-[(4-chlorophenyl)sulfonylmethyl]-2-methylpyrimidine SMR000170321 4-chlorophenyl {6-[(4-chlorophenyl)sulfanyl]-2-methyl-4-pyrimidinyl}methyl sulfone
N'-[2-(4-chlorophenyl)quinoline-4-carbonyl]-2-morpholin-4-yl-1,3-thiazole-4-carbohydrazide N'-[2-(4-chlorophenyl)quinoline-4-carbonyl]-2-morpholino-thiazole-4-carbohydrazide SMR000710234 N'-[2-(4-chlorophenyl)quinolin-4-yl]carbonyl-2-morpholin-4-yl-1,3-thiazole-4-carbohydrazide cid_24687197 BDBM58937 MLS001098023 N'-[[2-(4-chlorophenyl)-4-quinolinyl]-oxomethyl]-2-(4-morpholinyl)-4-thiazolecarbohydrazide
[1-[(1-methylpyrazol-4-yl)methyl]-4-p-anisyl-4-piperidyl]methanol [4-[(4-methoxyphenyl)methyl]-1-[(1-methylpyrazol-4-yl)methyl]piperidin-4-yl]methanol BDBM59483 cid_16188774 MLS000735433 [4-[(4-methoxyphenyl)methyl]-1-[(1-methyl-4-pyrazolyl)methyl]-4-piperidinyl]methanol SMR000319490 {4-(4-methoxybenzyl)-1-[(1-methyl-1H-pyrazol-4-yl)methyl]piperidin-4-yl}methanol
4-methyl-7-[4-[4-(4-nitrophenyl)piperazine-1-carbonyl]benzyl]oxy-coumarin 4-methyl-7-[[4-[4-(4-nitrophenyl)piperazin-1-yl]carbonylphenyl]methoxy]chromen-2-one 4-methyl-7-[[4-[4-(4-nitrophenyl)piperazine-1-carbonyl]phenyl]methoxy]chromen-2-one cid_4875603 MLS000334516 SMR000249274 4-methyl-7-[[4-[[4-(4-nitrophenyl)-1-piperazinyl]-oxomethyl]phenyl]methoxy]-1-benzopyran-2-one BDBM59468
cid_24178277 3-[4-keto-4-(4-phenylpiperidino)butyl]-2-thioxo-1H-quinazolin-4-one 3-[4-oxidanylidene-4-(4-phenylpiperidin-1-yl)butyl]-2-sulfanylidene-1H-quinazolin-4-one AS-1008-54 3-[4-oxo-4-(4-phenyl-1-piperidinyl)butyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-oxo-4-(4-phenylpiperidin-1-yl)butyl]-2-sulfanylidene-1H-quinazolin-4-one BDBM42013
1-[4-(4-bromophenyl)-2-thiazolyl]-4-(1-piperidinyl)-4-piperidinecarboxamide 1-[4-(4-bromophenyl)thiazol-2-yl]-4-piperidino-isonipecotamide SMR000144918 1'-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-1,4'-bipiperidine-4'-carboxamide 1-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-4-piperidin-1-yl-piperidine-4-carboxamide BDBM40171 MLS000539281 1-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-4-piperidin-1-ylpiperidine-4-carboxamide cid_991000
(Z)-4-keto-4-[4-[4-(o-tolyl)piperazino]anilino]but-2-enoic acid (Z)-4-[[4-[4-(2-methylphenyl)piperazin-1-yl]phenyl]amino]-4-oxidanylidene-but-2-enoic acid (Z)-4-[4-[4-(2-methylphenyl)-1-piperazinyl]anilino]-4-oxo-2-butenoic acid SMR000231950 MLS000704674 BDBM59477 4-{4-[4-(2-methylphenyl)-1-piperazinyl]anilino}-4-oxo-2-butenoicacid cid_1820245 (Z)-4-[4-[4-(2-methylphenyl)piperazin-1-yl]anilino]-4-oxobut-2-enoic acid
4-[4-chloro-6-[4-(4-methoxyphenyl)piperazino]-s-triazin-2-yl]morpholine cid_1146267 SMR000120392 BDBM44855 4-[4-chloranyl-6-[4-(4-methoxyphenyl)piperazin-1-yl]-1,3,5-triazin-2-yl]morpholine MLS000527818 4-[4-chloro-6-[4-(4-methoxyphenyl)piperazin-1-yl]-1,3,5-triazin-2-yl]morpholine 2-Chloro-4-[4-(4-methoxy-phenyl)-piperazin-1-yl]-6-morpholin-4-yl-[1,3,5]triazine 4-[4-chloro-6-[4-(4-methoxyphenyl)-1-piperazinyl]-1,3,5-triazin-2-yl]morpholine
BDBM67269 [2-(4-methyl-3-nitrophenyl)-2-oxoethyl] 4-(4-acetamidoanilino)-4-oxobutanoate SMR000269298 2-(4-methyl-3-nitrophenyl)-2-oxoethyl 4-{[4-(acetylamino)phenyl]amino}-4-oxobutanoate 4-(4-acetamidoanilino)-4-keto-butyric acid [2-keto-2-(4-methyl-3-nitro-phenyl)ethyl] ester 4-(4-acetamidoanilino)-4-oxobutanoic acid [2-(4-methyl-3-nitrophenyl)-2-oxoethyl] ester cid_2285716 [2-(4-methyl-3-nitro-phenyl)-2-oxidanylidene-ethyl] 4-[(4-acetamidophenyl)amino]-4-oxidanylidene-butanoate MLS000681039
2-(4-bromophenyl)-N-morpholin-4-yl-quinoline-4-carboxamide 2-(4-bromophenyl)-N-morpholino-cinchoninamide MLS000336201 cid_2418702 2-(4-bromophenyl)-N-(4-morpholinyl)-4-quinolinecarboxamide 2-(4-bromophenyl)-N-morpholin-4-ylquinoline-4-carboxamide SMR000253755 BDBM48761
BDBM34439 4-(morpholine-4-carbothioyl)benzoic acid methyl ester 4-[4-morpholinyl(sulfanylidene)methyl]benzoic acid methyl ester SMR000078965 MLS000051088 methyl 4-(4-morpholinylcarbonothioyl)benzoate methyl 4-(morpholine-4-carbothioyl)benzoate methyl 4-morpholin-4-ylcarbothioylbenzoate cid_974575
BDBM89970 2-(4-methoxyphenoxy)-4-phenyl-3-pyridinecarbonitrile SMR000179179 2-(4-methoxyphenoxy)-4-phenyl-nicotinonitrile 2-(4-methoxyphenoxy)-4-phenylnicotinonitrile cid_1487474 2-(4-methoxyphenoxy)-4-phenylpyridine-3-carbonitrile 2-(4-methoxyphenoxy)-4-phenyl-pyridine-3-carbonitrile MLS000326628
4-[[2-(4-nitrophenyl)quinazolin-4-yl]amino]benzoic acid BDBM82958 MLS001196815 4-[[2-(4-nitrophenyl)-4-quinazolinyl]amino]benzoic acid 4-{[2-(4-nitrophenyl)quinazolin-4-yl]amino}benzoic acid cid_1187249 SMR000555964
MLS002245724 cid_4789155 N-(4-methoxyphenyl)-4-(4-methylpiperidin-1-yl)carbonyl-benzenesulfonamide N-(4-methoxyphenyl)-4-[(4-methyl-1-piperidinyl)-oxomethyl]benzenesulfonamide N-(4-methoxyphenyl)-4-(4-methylpiperidine-1-carbonyl)benzenesulfonamide BDBM91337 SMR001309366
cid_20958586 1-(4-chlorophenyl)-4-[(1-methyl-4-imidazolyl)sulfonyl]piperazine 1-(4-chlorophenyl)-4-(1-methylimidazol-4-yl)sulfonyl-piperazine BDBM75240 MLS001095828 1-(4-chlorophenyl)-4-(1-methylimidazol-4-yl)sulfonylpiperazine SMR000631482
cid_2204303 N-(4-fluorophenyl)-4-{[(4-fluorophenyl)amino]sulfonyl}-2-thiophenecarboxamide N-(4-fluorophenyl)-4-[(4-fluorophenyl)sulfamoyl]-2-thiophenecarboxamide SMR000199685 MLS000580154 BDBM77439 N-(4-fluorophenyl)-4-[(4-fluorophenyl)sulfamoyl]thiophene-2-carboxamide
(4-bromophenyl)-(4-methylpiperazino)methanethione SMR000198953 cid_848272 (4-bromophenyl)-(4-methyl-1-piperazinyl)methanethione BDBM81042 1-[(4-bromophenyl)carbonothioyl]-4-methylpiperazine (4-bromophenyl)-(4-methylpiperazin-1-yl)methanethione MLS000579518
(4-formylphenyl) 2-(4-fluorophenyl)acetate 4-formylphenyl (4-fluorophenyl)acetate (4-methanoylphenyl) 2-(4-fluorophenyl)ethanoate MLS001180493 2-(4-fluorophenyl)acetic acid (4-formylphenyl) ester BDBM63940 cid_820021 SMR000477394
1-[(4-bromophenyl)carbonothioyl]-4-ethylpiperazine (4-bromophenyl)-(4-ethylpiperazin-1-yl)methanethione (4-bromophenyl)-(4-ethyl-1-piperazinyl)methanethione (4-bromophenyl)-(4-ethylpiperazino)methanethione BDBM88724 MLS000576805 cid_888529 SMR000198085
4-(4-benzylpiperidin-1-yl)sulfonylaniline 4-[4-(phenylmethyl)piperidin-1-yl]sulfonylaniline MLS001174462 BDBM64172 SMR000588410 [4-(4-benzylpiperidino)sulfonylphenyl]amine 4-[[4-(phenylmethyl)-1-piperidinyl]sulfonyl]aniline cid_2115228
BDBM80129 cid_888688 1-[(4-chlorophenyl)carbonothioyl]-4-ethylpiperazine (4-chlorophenyl)-(4-ethylpiperazin-1-yl)methanethione MLS000594090 (4-chlorophenyl)-(4-ethylpiperazino)methanethione (4-chlorophenyl)-(4-ethyl-1-piperazinyl)methanethione SMR000143149
cid_1569734 4-(2,5-dimethylphenoxy)-N-(4-morpholinophenyl)butyramide 4-(2,5-dimethylphenoxy)-N-[4-(4-morpholinyl)phenyl]butanamide 4-(2,5-dimethylphenoxy)-N-(4-morpholin-4-ylphenyl)butanamide SMR000072793 BDBM30902 MLS000089110
cid_2183668 MLS000594042 2-[4-(4-chloranylphenoxy)butylsulfanyl]pyrimidine 2-[4-(4-chlorophenoxy)butylthio]pyrimidine 2-{[4-(4-chlorophenoxy)butyl]thio}pyrimidine BDBM87733 SMR000143101 2-[4-(4-chlorophenoxy)butylsulfanyl]pyrimidine
2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one CHEMBL241909 4'-Methoxyflavanone (+/-)-2-(4-methoxyphenyl)chroman-4-one BDBM50310195 NSC-50187 2-(4-methoxyphenyl)chroman-4-one
4-amino-N-[4-(aminosulfonyl)phenyl]benzenesulfonamide 4-amino-bis-benzenesulfonamide 4-amino-N-(4-sulfamoylphenyl)benzenesulfonamide BDBM50080733 4-(4-aminophenylsulfonamido)-1-benzenesulfonamide CHEMBL269122 cid_68351
4-(4-Morpholin-4-yl-phenylamino)-quinoline-3,6-dicarboxylic acid diethyl ester 4-(4-morpholinoanilino)quinoline-3,6-dicarboxylic acid diethyl ester 4-[4-(4-morpholinyl)anilino]quinoline-3,6-dicarboxylic acid diethyl ester cid_1190175 MLS000590451 diethyl 4-(4-morpholin-4-ylanilino)quinoline-3,6-dicarboxylate BDBM68992 SMR000217520 diethyl 4-[(4-morpholin-4-ylphenyl)amino]quinoline-3,6-dicarboxylate
4-(4-acetylphenyl)-N-p-cumenyl-piperazine-1-carboxamide 4-(4-acetylphenyl)-N-(4-propan-2-ylphenyl)piperazine-1-carboxamide 4-(4-acetylphenyl)-N-(4-propan-2-ylphenyl)-1-piperazinecarboxamide BDBM94728 MLS000660726 4-(4-ethanoylphenyl)-N-(4-propan-2-ylphenyl)piperazine-1-carboxamide SMR000310244 cid_16012854 4-(4-acetylphenyl)-N-(4-isopropylphenyl)piperazine-1-carboxamide
4-[2-phenyl-6-(p-tolylthio)pyrimidin-4-yl]morpholine SMR000179171 cid_1484653 MLS000326647 4-[6-(4-methylphenyl)sulfanyl-2-phenyl-pyrimidin-4-yl]morpholine 4-[6-(4-methylphenyl)sulfanyl-2-phenylpyrimidin-4-yl]morpholine 4-{6-[(4-methylphenyl)sulfanyl]-2-phenyl-4-pyrimidinyl}morpholine 4-[6-[(4-methylphenyl)thio]-2-phenyl-4-pyrimidinyl]morpholine BDBM84237
4-chloro-3-morpholin-4-ylsulfonyl-N-(pyridin-4-ylmethyl)benzamide 4-chloranyl-3-morpholin-4-ylsulfonyl-N-(pyridin-4-ylmethyl)benzamide 4-Chloro-3-(morpholine-4-sulfonyl)-N-pyridin-4-ylmethyl-benzamide cid_647664 MLS000076032 4-chloro-3-(4-morpholinylsulfonyl)-N-(pyridin-4-ylmethyl)benzamide SMR000014877 4-chloro-3-morpholinosulfonyl-N-(4-pyridylmethyl)benzamide BDBM62540
SMR000199177 BDBM52419 N-(4-methoxyphenyl)-4-{[3-(4-morpholinyl)propyl]amino}-3-nitrobenzamide cid_2947781 N-(4-methoxyphenyl)-4-(3-morpholin-4-ylpropylamino)-3-nitrobenzamide N-(4-methoxyphenyl)-4-[3-(4-morpholinyl)propylamino]-3-nitrobenzamide N-(4-methoxyphenyl)-4-(3-morpholin-4-ylpropylamino)-3-nitro-benzamide N-(4-methoxyphenyl)-4-(3-morpholinopropylamino)-3-nitro-benzamide MLS000579937
cid_3933628 N-(4-methyl-3-morpholin-4-ylsulfonylphenyl)-4-morpholin-4-yl-3-nitrobenzamide N-(4-methyl-3-morpholinosulfonyl-phenyl)-4-morpholino-3-nitro-benzamide BDBM84254 N-(4-methyl-3-morpholin-4-ylsulfonyl-phenyl)-4-morpholin-4-yl-3-nitro-benzamide N-[4-methyl-3-(4-morpholinylsulfonyl)phenyl]-4-(4-morpholinyl)-3-nitrobenzamide SMR000241421 MLS000393695
1-(4-Chloroanilino)-4-(4-pyrimidylmethyl)phthalazine BDBM4857 CGP79787 Analog 42 N-(4-chlorophenyl)-4-(pyrimidin-4-ylmethyl)phthalazin-1-amine
4-(4-(pyridin-4-yl)thiazol-2-ylamino)phenol BDBM50312874 CHEMBL565257 4-{[4-(4-Pyridinyl)-1,3-thiazol-2-yl]amino}phenol
4-(4-Fluoro-phenyl)-1-[1-(4-fluoro-phenyl)-piperidin-4-yl]-4-(4-nitro-phenoxy)-butan-1-one BDBM50136208 CHEMBL153716
4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole CHEMBL63135 BDBM50053410 4-[5-(4-Fluoro-phenyl)-3H-imidazol-4-yl]-pyridine
BDBM22425 4-hydroxytamoxifen (4-OHT) analog, 5 (4Z)-5-{4-[2-(dimethylamino)ethoxy]phenyl}-5-(4-hydroxyphenyl)-4-phenylpent-4-enenitrile
CGP79787 Analog 58 BDBM4873 1-(4-Biphenylamino)-4-(4-pyridylmethyl)phthalazine N-(4-phenylphenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
CHEMBL1083585 4-(4-(4-(4-(4-acetylphenyl)piperazine-1-carbonyl)piperidin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide BDBM50320436
CHEMBL1085787 BDBM50320435 4-(4-(4-(4-(4-fluorophenyl)piperazine-1-carbonyl)piperidin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide
CHEMBL150578 BDBM50136177 4-(4-Amino-phenoxy)-4-(4-fluoro-phenyl)-1-[1-(4-fluoro-phenyl)-piperidin-4-yl]-butan-1-one
MLS000679492 N-(4-ethylphenyl)-4-(4-fluorophenyl)-1-piperazinecarboxamide N-(4-ethylphenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide BDBM59488 cid_6467355 SMR000297652
MLS000834817 cid_2812572 N'-(4-chlorophenyl)-4-ethyl-benzohydrazide SMR000458435 N'-(4-chlorophenyl)-4-ethylbenzohydrazide BDBM67306 N'-(4-chlorophenyl)-4-ethylbenzohydrazide
SMR000081069 MLS000051916 cid_752006 N-(4-anilinophenyl)morpholine-4-carboxamide N-(4-phenylazanylphenyl)morpholine-4-carboxamide BDBM60385 N-(4-anilinophenyl)-4-morpholinecarboxamide
US11718616, Example 4 US10526330, Example 4 US10100049, Example 4 US10913740, Example 4-2 BDBM292107 US10183942, Example 4-2 US11299492, Example 4
cid_1011074 BDBM114085 N-(4-anilinophenyl)-4-methoxybenzenesulfonamide 4-methoxy-N-(4-phenylazanylphenyl)benzenesulfonamide N-(4-anilinophenyl)-4-methoxy-benzenesulfonamide MLS001179478 SMR000476739
1-[(4-fluorophenyl)methyl]-4-piperidin-1-ylpiperidine-4-carboxamide 1-(4-fluorobenzyl)-4-piperidino-isonipecotamide MLS000539254 SMR000144891 1-[(4-fluorophenyl)methyl]-4-piperidin-1-yl-piperidine-4-carboxamide 1-[(4-fluorophenyl)methyl]-4-(1-piperidinyl)-4-piperidinecarboxamide 1'-(4-fluorobenzyl)-1,4'-bipiperidine-4'-carboxamide BDBM56356 cid_1830278
N-(4-methylphenyl)-2-pyridin-4-ylquinazolin-4-amine SMR000434261 N-(4-methylphenyl)-2-pyridin-4-yl-4-quinazolinamine (2-Pyridin-4-yl-quinazolin-4-yl)-p-tolyl-amine BDBM69457 cid_748627 MLS000769531 N-(4-methylphenyl)-2-pyridin-4-yl-quinazolin-4-amine p-tolyl-[2-(4-pyridyl)quinazolin-4-yl]amine
cid_1000682 N-[4-(acetylsulfamoyl)phenyl]-2-(4-methylphenyl)-4-quinolinecarboxamide N-[4-(acetylsulfamoyl)phenyl]-2-(p-tolyl)cinchoninamide SMR000197731 MLS000578544 N-[4-(acetylsulfamoyl)phenyl]-2-(4-methylphenyl)quinoline-4-carboxamide N-[4-(ethanoylsulfamoyl)phenyl]-2-(4-methylphenyl)quinoline-4-carboxamide BDBM59930 N-{4-[(acetylamino)sulfonyl]phenyl}-2-(4-methylphenyl)-4-quinolinecarboxamide
(1Z)-4-(4-fluorophenoxy)-3-nitro-benzaldoxime BDBM69292 N-[[4-(4-fluoranylphenoxy)-3-nitro-phenyl]methylidene]hydroxylamine 4-(4-fluorophenoxy)-3-nitro-benzaldoxime 4-(4-fluorophenoxy)-3-nitrobenzenecarbaldehyde oxime MLS000694759 N-[[4-(4-fluorophenoxy)-3-nitrophenyl]methylidene]hydroxylamine SMR000333077 4-(4-fluorophenoxy)-3-nitrobenzaldehyde oxime cid_1480401
4-(2-methyl-4-quinolyl)piperazine-1-carboxylic acid (4-nitrophenyl) ester cid_46829224 BDBM95033 (4-nitrophenyl) 4-(2-methylquinolin-4-yl)piperazine-1-carboxylate MLS003173352 4-nitrophenyl 4-(2-methylquinolin-4-yl)piperazine-1-carboxylate 4-(2-methyl-4-quinolinyl)-1-piperazinecarboxylic acid (4-nitrophenyl) ester SMR001877206
4-(4-chlorophenyl)-2-(2,2-dimethyltetrahydrothiopyran-4-yl)thiazole;hydrochloride 4-(4-chlorophenyl)-2-(2,2-dimethylthian-4-yl)-1,3-thiazole;hydrochloride MLS000560970 4-(4-Chloro-phenyl)-2-(2,2-dimethyl-tetrahydro-thiopyran-4-yl)-thiazole cid_11957319 BDBM57333 4-(4-chlorophenyl)-2-(2,2-dimethyl-4-thianyl)thiazole;hydrochloride SMR000174845
4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile 4-(4-(4-methoxypyridin-2-ylamino)piperidine-1-carbonyl)benzonitrile CHEMBL114500 4-[4-(4-Methoxy-pyridin-2-ylamino)-piperidine-1-carbonyl]-benzonitrile BDBM50148167 4-[4-[(4-Methoxypyridin-2-yl)amino]piperidine-1-carbonyl]benzonitrile, 12
4-[4-(4-methoxyphenyl)piperazin-1-yl]-5H-pyrimido[5,4-b]indole BDBM89255 SMR000125212 MLS000539554 4-[4-(4-methoxyphenyl)piperazino]-5H-pyrimido[5,4-b]indole 4-[4-(4-methoxyphenyl)piperazino]-5H-pyrimid[5,4-b]indole cid_1475855 4-[4-(4-methoxyphenyl)-1-piperazinyl]-5H-pyrimido[5,4-b]indole
6-methoxy-4-[4-(4-methoxyphenyl)piperazino]-2-methyl-quinoline 6-methoxy-4-[4-(4-methoxyphenyl)piperazin-1-yl]-2-methylquinoline BDBM69868 SMR000591873 6-methoxy-4-[4-(4-methoxyphenyl)-1-piperazinyl]-2-methylquinoline MLS001174346 6-methoxy-4-[4-(4-methoxyphenyl)piperazin-1-yl]-2-methyl-quinoline cid_4782568
CHEMBL1622565 MLS000562232 SMR000177579 4-(4-chlorophenyl)-2-(2-propylpyridin-4-yl)-1,3-thiazole;hydrobromide 4-[4-(4-Chloro-phenyl)-thiazol-2-yl]-2-propyl-pyridine cid_2852359 4-(4-chlorophenyl)-2-(2-propyl-4-pyridyl)thiazole;hydrobromide BDBM93773 4-(4-chlorophenyl)-2-(2-propyl-4-pyridinyl)thiazole;hydrobromide
N-(4-methoxyphenyl)-3-[4-(4-methoxyphenyl)sulfonylpiperazino]propionamide BDBM63452 N-(4-methoxyphenyl)-3-[4-(4-methoxyphenyl)sulfonyl-1-piperazinyl]propanamide N-(4-methoxyphenyl)-3-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]propanamide SMR000315082 cid_15996463 N-(4-methoxyphenyl)-3-{4-[(4-methoxyphenyl)sulfonyl]piperazin-1-yl}propanamide MLS000673841
SMR000595679 acetic acid [4-[4-[2-(4-sulfamoylphenyl)ethylcarbamoyl]phenyl]phenyl] ester BDBM61748 MLS001175129 [4-[4-[2-(4-sulfamoylphenyl)ethylcarbamoyl]phenyl]phenyl] ethanoate cid_2335790 [4-[4-[2-(4-sulfamoylphenyl)ethylcarbamoyl]phenyl]phenyl] acetate acetic acid [4-[4-[oxo-[2-(4-sulfamoylphenyl)ethylamino]methyl]phenyl]phenyl] ester
cid_1317528 MLS000062853 N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester N-[4-[4-(4-hydroxyphenyl)piperazino]phenyl]carbamic acid phenyl ester phenyl {4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl}carbamate phenyl N-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]carbamate BDBM62766 SMR000073777
methyl 2-(4-fluorophenyl)-4-(3-methoxyphenyl)-4-oxobutanoate 2-(4-fluorophenyl)-4-keto-4-(3-methoxyphenyl)butyric acid methyl ester methyl 2-(4-fluorophenyl)-4-(3-methoxyphenyl)-4-oxidanylidene-butanoate SMR000334221 BDBM90559 2-(4-fluorophenyl)-4-(3-methoxyphenyl)-4-oxobutanoic acid methyl ester MLS000720878 cid_4360233
1-(4-butylphenyl)-3-[4-[(4-methoxyphenyl)amino]phenyl]thiourea 1-(4-butylphenyl)-3-[4-(4-methoxyanilino)phenyl]thiourea 1-(4-butylphenyl)-3-[4-(p-anisidino)phenyl]thiourea BDBM78165 cid_2958851 MLS000581540 SMR000200168 N-(4-butylphenyl)-N'-{4-[(4-methoxyphenyl)amino]phenyl}thiourea
4-(5-fluoro-2-morpholino-pyrimidin-4-yl)morpholine cid_616971 SMR000285020 BDBM94396 MLS000687397 4-(5-fluoro-2-morpholin-4-ylpyrimidin-4-yl)morpholine 4-[5-fluoro-2-(4-morpholinyl)-4-pyrimidinyl]morpholine 4-(5-fluoranyl-2-morpholin-4-yl-pyrimidin-4-yl)morpholine
4-[(2,6-dimethyl-4-morpholinyl)-oxomethyl]-N-(4-ethoxyphenyl)benzenesulfonamide SMR001271678 cid_18108400 4-(2,6-dimethylmorpholine-4-carbonyl)-N-p-phenetyl-benzenesulfonamide 4-(2,6-dimethylmorpholine-4-carbonyl)-N-(4-ethoxyphenyl)benzenesulfonamide BDBM91216 4-(2,6-dimethylmorpholin-4-yl)carbonyl-N-(4-ethoxyphenyl)benzenesulfonamide MLS002182648
4-[(2,6-dimethyl-4-morpholinyl)-oxomethyl]-N-(4-methylphenyl)benzenesulfonamide 4-(2,6-dimethylmorpholine-4-carbonyl)-N-(4-methylphenyl)benzenesulfonamide cid_24816588 BDBM91063 MLS001031768 4-(2,6-dimethylmorpholin-4-yl)carbonyl-N-(4-methylphenyl)benzenesulfonamide 4-(2,6-dimethylmorpholine-4-carbonyl)-N-(p-tolyl)benzenesulfonamide SMR000715282
4-tert-butyl-N-[[4-(4-morpholinyl)anilino]-sulfanylidenemethyl]benzamide BDBM89301 4-tert-butyl-N-[(4-morpholin-4-ylphenyl)carbamothioyl]benzamide SMR000228856 cid_1227109 4-tert-butyl-N-[(4-morpholinophenyl)thiocarbamoyl]benzamide MLS000698072 N-(4-tert-butylbenzoyl)-N'-[4-(4-morpholinyl)phenyl]thiourea
BDBM100015 [2-(4-ethoxyphenyl)-4-quinolinyl]-(4-methyl-1-piperazinyl)methanone cid_1540951 2-(4-ethoxyphenyl)-4-[(4-methylpiperazin-1-yl)carbonyl]quinoline SMR000031815 MLS000254486 (4-methylpiperazino)-(2-p-phenetyl-4-quinolyl)methanone [2-(4-ethoxyphenyl)quinolin-4-yl]-(4-methylpiperazin-1-yl)methanone
BDBM70056 SMR000670411 2-[(4-fluorophenyl)thio]-N-(4-morpholinophenyl)acetamide 2-(4-fluorophenyl)sulfanyl-N-(4-morpholin-4-ylphenyl)acetamide 2-(4-fluorophenyl)sulfanyl-N-(4-morpholin-4-ylphenyl)ethanamide 2-[(4-fluorophenyl)thio]-N-[4-(4-morpholinyl)phenyl]acetamide cid_2994341 MLS001162593
N-(4-benzhydrylpiperazine-1-carbothioyl)-4-morpholin-4-ylsulfonylbenzamide N-[[4-(diphenylmethyl)-1-piperazinyl]-sulfanylidenemethyl]-4-(4-morpholinylsulfonyl)benzamide cid_3996696 MLS000418682 BDBM57618 N-[4-(diphenylmethyl)piperazin-1-yl]carbothioyl-4-morpholin-4-ylsulfonyl-benzamide N-(4-benzhydrylpiperazine-1-carbothioyl)-4-morpholinosulfonyl-benzamide SMR000247542
N-(4-methyl-3-morpholin-4-ylsulfonyl-phenyl)-4-phenoxy-butanamide N-(4-methyl-3-morpholin-4-ylsulfonylphenyl)-4-phenoxybutanamide MLS002166990 SMR001249325 N-[4-methyl-3-(4-morpholinylsulfonyl)phenyl]-4-phenoxybutanamide BDBM74345 N-(4-methyl-3-morpholinosulfonyl-phenyl)-4-phenoxy-butyramide cid_7929118
N-(4-methyl-3-morpholin-4-ylsulfonyl-phenyl)-4-phenylsulfanyl-butanamide SMR000372371 MLS000761060 N-(4-methyl-3-morpholinosulfonyl-phenyl)-4-(phenylthio)butyramide N-[4-methyl-3-(4-morpholinylsulfonyl)phenyl]-4-(phenylthio)butanamide N-(4-methyl-3-morpholin-4-ylsulfonylphenyl)-4-phenylsulfanylbutanamide BDBM44146 cid_4880562
SMR000069811 [4-[oxo(pyridin-4-yl)methyl]-1-piperazinyl]-pyridin-4-ylmethanone cid_706240 (4-isonicotinoylpiperazino)-(4-pyridyl)methanone 1,4-diisonicotinoylpiperazine MLS000061046 BDBM74457 pyridin-4-yl-(4-pyridin-4-ylcarbonylpiperazin-1-yl)methanone [4-(pyridine-4-carbonyl)piperazin-1-yl]-pyridin-4-ylmethanone
1-[4-(4-Amino-phenyl)-but-3-ynyl]-4-(4-methyl-benzyl)-piperidin-4-ol CHEMBL84227 BDBM50078489
1-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-4-isopropylamino-piperidine-4-carboxylic acid amide CHEMBL147418 BDBM50068521
1-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-4-methylamino-piperidine-4-carboxylic acid amide BDBM50068526 CHEMBL147363
2-[4-(4-Florophenyl)piperazine-1-yl]-4-[4-(2-methylthiazol-4-yl)phenyl]acetamide (5h) BDBM243030
4-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-(4-chlorophenyl)-4-oxobutanamide BDBM50175840 CHEMBL200842
4-(4-(4-(4-chlorophenyl)piperidin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide BDBM50320393 CHEMBL1084221
4-(4-fluorophenyl)-1H-imidazole 5-(4-fluorophenyl)-1H-imidazole 4-(4-fluorophenyl)-1H-imidazole, 9 BDBM24671
4-(AMINOSULFONYL)-N-[(4-FLUOROPHENYL)METHYL]-BENZAMIDE N-[(4-fluorophenyl)methyl]-4-sulfamoylbenzamide BDBM12015 4-fluoro-SBB
4-[4-(4-chloro-benzyloxy)-benzenesulfonyl]-1-(4-methyl-benzyl)-piperidine-4-carboxylic acid hydroxyamide BDBM50128647 CHEMBL312432
4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one BDBM32365
BDBM50027202 CHEMBL198332 4-(4-Chloro-phenyl)-1-[4-(3,4-dichloro-phenyl)-4-phenyl-butyl]-piperidin-4-ol
BDBM50068527 4-Amino-1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-piperidine-4-carboxylic acid amide CHEMBL422498
BDBM50078490 CHEMBL312384 1-[4-(4-Amino-phenyl)-but-3-ynyl]-4-(4-fluoro-benzyl)-piperidin-4-ol
BDBM50320413 4-(4-(4-(4-chlorophenyl)piperazin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide CHEMBL1084509
CHEMBL356075 4-Cyclohexylamino-1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-piperidine-4-carboxylic acid amide BDBM50068525
US10617673, Example 4 US9987253, Example 4 US11179370, Example 4 US9517228, Example 4 (2S,4′S) BDBM286106
US9663506, Example 4-115 US9278960, 4-114 US9278960, 4-115 US9278960, 4-112 US9278960, 4-113 BDBM213028
US9708253, 112 4-((1s,4s)-4-(4-fluorophenylsulfonyl)-4-(4-(perfluoropropan-2-yl)phenyl)cyclohexyl)morpholine BDBM261453
SMR000198100 (4-bromophenyl)-[4-(phenylmethyl)piperazin-1-yl]methanethione 1-benzyl-4-[(4-bromophenyl)carbonothioyl]piperazine MLS000576820 (4-benzylpiperazin-1-yl)-(4-bromophenyl)methanethione (4-bromophenyl)-[4-(phenylmethyl)-1-piperazinyl]methanethione (4-benzylpiperazino)-(4-bromophenyl)methanethione BDBM88723 cid_2185493
3-[4-[4-(4-acetylphenyl)piperazin-1-yl]-4-oxobutyl]-6-bromo-1H-quinazoline-2,4-dione 3-[4-[4-(4-acetylphenyl)piperazino]-4-keto-butyl]-6-bromo-1H-quinazoline-2,4-quinone SMR000308349 3-{4-[4-(4-acetylphenyl)piperazin-1-yl]-4-oxobutyl}-6-bromoquinazoline-2,4(1H,3H)-dione MLS000730072 6-bromanyl-3-[4-[4-(4-ethanoylphenyl)piperazin-1-yl]-4-oxidanylidene-butyl]-1H-quinazoline-2,4-dione 3-[4-[4-(4-acetylphenyl)-1-piperazinyl]-4-oxobutyl]-6-bromo-1H-quinazoline-2,4-dione cid_16193181 BDBM95745
4-[4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-1-(4-methoxyphenyl)sulfonylpiperidine 4-[4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-1-(4-methoxyphenyl)sulfonyl-piperidine MLS000331358 SMR000168795 4-[4-ethyl-5-[(4-methylbenzyl)thio]-1,2,4-triazol-3-yl]-1-(4-methoxyphenyl)sulfonyl-piperidine 4-{4-ethyl-5-[(4-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-3-yl}-1-[(4-methoxyphenyl)sulfonyl]piperidine cid_1477735 4-[4-ethyl-5-[(4-methylphenyl)methylthio]-1,2,4-triazol-3-yl]-1-(4-methoxyphenyl)sulfonylpiperidine BDBM52387
4-[[3-[(4-methoxyphenyl)carbamoyl]-4-methyl-5-phenylthiophen-2-yl]amino]-4-oxobutanoic acid MLS000685740 4-[[3-[(4-methoxyphenyl)carbamoyl]-4-methyl-5-phenyl-thiophen-2-yl]amino]-4-oxidanylidene-butanoic acid 4-[[3-[(4-methoxyanilino)-oxomethyl]-4-methyl-5-phenyl-2-thiophenyl]amino]-4-oxobutanoic acid cid_1253935 4-[(3-{[(4-methoxyphenyl)amino]carbonyl}-4-methyl-5-phenylthien-2-yl)amino]-4-oxobutanoic acid BDBM96458 SMR000312704 4-keto-4-[[3-[(4-methoxyphenyl)carbamoyl]-4-methyl-5-phenyl-2-thienyl]amino]butyric acid
4-{2-[(2-bromo-4-methylphenoxy)acetyl]hydrazino}-N-(4-ethoxyphenyl)-4-oxobutanamide cid_5165670 BDBM62506 4-[[2-(2-bromo-4-methylphenoxy)-1-oxoethyl]hydrazo]-N-(4-ethoxyphenyl)-4-oxobutanamide 4-[2-[2-(2-bromanyl-4-methyl-phenoxy)ethanoyl]hydrazinyl]-N-(4-ethoxyphenyl)-4-oxidanylidene-butanamide SMR000672963 4-[N'-[2-(2-bromo-4-methyl-phenoxy)acetyl]hydrazino]-4-keto-N-p-phenetyl-butyramide MLS001147906 4-[2-[2-(2-bromo-4-methylphenoxy)acetyl]hydrazinyl]-N-(4-ethoxyphenyl)-4-oxobutanamide
1-(4-Chloroanilino)-4-(4-pyridylmethyl)-6-methylphthalazine and 1-(4-Chloroanilino)-4-(4-pyridylmethyl)-7-methylphthalazine Dihydrochloride N-(4-chlorophenyl)-7-methyl-4-(pyridin-4-ylmethyl)phthalazin-1-amine BDBM4863 CGP79787 Analog 46
1-Benzyl-4-(4-benzyloxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide 1-benzyl-4-(4-(benzyloxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide BDBM50128654 CHEMBL78369 1-Benzyl-4-(4-phenoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide
3-(4-hydroxyphenyl)-2-(4-hydroxyphenyl)imino-thiazolidin-4-one cid_657890 3-(4-hydroxyphenyl)-2-(4-hydroxyphenyl)imino-4-thiazolidinone MLS000027731 SMR000038851 BDBM40810 3-(4-hydroxyphenyl)-2-(4-hydroxyphenyl)imino-1,3-thiazolidin-4-one
4-chloro-N-[4-keto-4-(veratrylamino)butyl]benzamide SMR000588387 BDBM64182 4-chloranyl-N-[4-[(3,4-dimethoxyphenyl)methylamino]-4-oxidanylidene-butyl]benzamide MLS001174710 4-chloro-N-[4-[(3,4-dimethoxyphenyl)methylamino]-4-oxobutyl]benzamide cid_2472561
cid_2391681 BDBM89940 4-keto-N-(4-methylbenzyl)-4-(2-thienyl)butyramide SMR000151317 MLS000535920 N-[(4-methylphenyl)methyl]-4-oxidanylidene-4-thiophen-2-yl-butanamide N-[(4-methylphenyl)methyl]-4-oxo-4-thiophen-2-ylbutanamide
(E)-N-(4-bromophenyl)-4-(2-(4-fluorobenzylidene)hydrazinyl)-4-oxobutanamide BDBM50318656 CHEMBL1083060
1-[4-Chlorophenylsulfonyl]-4-[4-(4-methylpiperazin-1-yl)phenylmethyl]-piperazine BDBM50271622 CHEMBL484125
2-(4-fluorobenzyl)-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidine BDBM50297701 CHEMBL559952
4'-Trifluoromethyl-biphenyl-4-carboxylic acid CHEMBL108457 4'-(trifluoromethyl)-4-biphenylcarboxylic acid BDBM50060996
4'-ethyl-biphenyl-4-carboxylic acid BDBM50329374 CHEMBL443832 4'-ethylbiphenyl-4-carboxylic acid
4-(4-(4-chlorobenzyl)piperazin-1-yl)-N-(4-chlorophenyl)butanamide CHEMBL225857 BDBM50200236
4-(4-Hydroxy-phenyl)-1-(4-phenyl-butyl)-piperidin-4-ol BDBM50085922 CHEMBL174632
4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine BDBM32366
5-(4-chlorophenyl)-6-(4-morpholin-4-ylphenylethynyl)pyrimidin-4-ylamine BDBM50201852 CHEMBL225833
BDBM176821 US9675614, 4 US10980794, Cmpd No 4 US10307413, Compound 4 US10391089, Compound 4
BDBM394285 US11401280, Example 4 US10829502, Example 4 US9975907, Example 4 US10428087, Example 4
BDBM422047 US10556885, Compound 4 US11174244, Compound 4 US11673881, Compound 4 US10508099, Compound 4
BDBM50132655 4-(4-Chloro-phenyl)-1-(4-trifluoromethyl-benzyl)-piperidin-4-ol CHEMBL109803
BDBM50180604 CHEMBL377700 3-(4-Fluorobenzyl)-4-oxo-4-((4-phenylethynyl)phenyl)butyric acid
BDBM94219 4-(4-nitrobenzyl)pyridine 4-[(4-nitrophenyl)methyl]pyridine SMR000281726 cid_14129 MLS000711959
CHEMBL124813 BDBM50027201 4-(4-Chloro-phenyl)-1-(4-phenyl-butyl)-piperidin-4-ol
CHEMBL196486 4-[4-(4-Morpholin-4-yl-phenylamino)-phthalazin-1-yl]-benzamide BDBM50173032
CHEMBL198377 BDBM50175550 N-Hydroxy-4-oxo-4-[4-(pyridin-4-yloxy)-phenyl]-butyramide
CHEMBL36392 BDBM50180894 4-(4-Phenoxy-benzoyl)-benzoic acid 4-(4-phenoxybenzoyl)benzoic acid
CHEMBL370416 BDBM50175554 4-[4-(4-Chloro-phenoxy)-phenyl]-N-hydroxy-4-oxo-butyramide
CHEMBL387853 BDBM50200228 N-(4-chlorophenyl)-4-(4-(4-fluorophenyl)piperazin-1-yl)butanamide
Disubstituted imidazole 4 4-(4-methoxyphenyl)-1-[(4-methylphenyl)methyl]-1H-imidazole BDBM8739
N-(4-chlorophenyl)-4-(4-(4-chlorophenyl)piperazin-1-yl)butanamide BDBM50200223 CHEMBL390955
US10233189, Example 4 US11236096, Example 4 BDBM370346 US11014930, Example 4 US10787457, Example 4
US10399976, Compound 4 US10807980, Compound 4 BDBM317851 US9624217, Compound 4 US11535614, Compound 4
US10570125, Example 4 US11725004, Example 4 BDBM295693 US11084810, Example 4 US10112934, Example 4
US10844069, Example 4 BDBM396942 US10442810, Example 4 US11591338, Example 4 US9981975, Example 4
US11608338, Example 4 US10457677, Example 4 US10745399, Example 4 BDBM418436 US10975075, Example 4
US11691977, Example 4 BDBM284713 US10875867, Example 4 US10479794, Example 4 US10023575, Example 4
US20230338337, Example 4 BDBM427049 US10981898, Example 4 US11236047, Example 4 US10544132, Example 4
US9908895, Example 4 US11161855, Example 4 US10370387, Example 4 US9777017, Example 4 BDBM344020
(E)-4-[[4-[(2,6-dimethoxypyrimidin-4-yl)sulfamoyl]phenyl]amino]-4-oxidanylidene-but-2-enoic acid SMR000516273 MLS001210970 (E)-4-[4-[(2,6-dimethoxy-4-pyrimidinyl)sulfamoyl]anilino]-4-oxo-2-butenoic acid (E)-4-[4-[(2,6-dimethoxypyrimidin-4-yl)sulfamoyl]anilino]-4-keto-but-2-enoic acid (E)-4-[4-[(2,6-dimethoxypyrimidin-4-yl)sulfamoyl]anilino]-4-oxobut-2-enoic acid cid_5762148 3-[4-(2,6-Dimethoxy-pyrimidin-4-ylsulfamoyl)-phenylcarbamoyl]-acrylic acid BDBM64059
N-(4-methylphenyl)-4-(4-morpholin-4-yl-3-nitrophenyl)phthalazin-1-amine N-(4-methylphenyl)-4-(4-morpholin-4-yl-3-nitro-phenyl)phthalazin-1-amine [4-(4-morpholino-3-nitro-phenyl)phthalazin-1-yl]-(p-tolyl)amine BDBM45151 [4-(4-Morpholin-4-yl-3-nitro-phenyl)-phthalazin-1-yl]-p-tolyl-amine cid_6418532 N-(4-methylphenyl)-4-[4-(4-morpholinyl)-3-nitrophenyl]-1-phthalazinamine MLS000591749 SMR000218805
(4-methylpiperazin-1-yl)-(4-nitrophenyl)methanethione MLS000581483 BDBM81043 SMR000200110 cid_972260 (4-methylpiperazino)-(4-nitrophenyl)methanethione (4-methyl-1-piperazinyl)-(4-nitrophenyl)methanethione 1-methyl-4-[(4-nitrophenyl)carbonothioyl]piperazine
1-[(4-chlorophenyl)methylsulfonyl]-4-methylpiperazine 1-[(4-chlorobenzyl)sulfonyl]-4-methylpiperazine cid_2738373 MLS000850871 1-[(4-chlorophenyl)methylsulfonyl]-4-methyl-piperazine 1-(4-chlorobenzyl)sulfonyl-4-methyl-piperazine SMR000456888 BDBM33035
4-[4-(4-Fluoro-phenyl)-5-(2-methoxy-pyrimidin-4-yl)-imidazol-1-yl]-cyclohexanol BDBM50105742 trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)imidazole CHEMBL97162
4-chloro-N-(4-pyridyl)benzenesulfonamide 4-chloro-N-pyridin-4-ylbenzenesulfonamide MLS000523152 4-Chloro-N-pyridin-4-yl-benzenesulfonamide BDBM63045 SMR000123130 cid_674932 4-chloranyl-N-pyridin-4-yl-benzenesulfonamide
BDBM50075778 4-[5-(4-Fluoro-phenyl)-2-(4-methylsulfanyl-phenyl)-3H-imidazol-4-yl]-pyridine 4-[5-(4-Fluoro-phenyl)-2-(4-methylsulfanyl-phenyl)-1H-imidazol-4-yl]-pyridine CHEMBL17370
BDBM78642 1-[4-(4-acetylphenyl)sulfanylphenyl]ethanone 1-[4-(4-ethanoylphenyl)sulfanylphenyl]ethanone SMR000177655 1-[4-[(4-acetylphenyl)thio]phenyl]ethanone 1-[4-(4-Acetyl-phenylsulfanyl)-phenyl]-ethanone cid_520243 MLS000551865
BDBM93877 [4-(4-phenoxyphenyl)thiazol-2-yl]amine cid_780598 4-(4-phenoxyphenyl)-1,3-thiazol-2-amine SMR000515826 MLS001209112 4-(4-Phenoxy-phenyl)-thiazol-2-ylamine 4-(4-phenoxyphenyl)-2-thiazolamine
N'-(4-methylbenzylidene)-4-morpholinecarbothiohydrazide N-[(4-methylbenzylidene)amino]morpholine-4-carbothioamide cid_829184 N-[(4-methylphenyl)methylideneamino]-4-morpholinecarbothioamide MLS000699197 SMR000225240 BDBM67249 N-[(4-methylphenyl)methylideneamino]morpholine-4-carbothioamide
cid_651533 MLS000072398 4-Phenoxy-N-pyridin-4-yl-butyramide 4-phenoxy-N-pyridin-4-ylbutanamide BDBM37875 4-phenoxy-N-(4-pyridyl)butyramide SMR000012458 4-phenoxy-N-pyridin-4-yl-butanamide
cid_829182 N-[(4-chlorobenzylidene)amino]morpholine-4-carbothioamide SMR000225239 BDBM45262 MLS000701369 N-[(4-chlorophenyl)methylideneamino]-4-morpholinecarbothioamide N'-(4-chlorobenzylidene)-4-morpholinecarbothiohydrazide N-[(4-chlorophenyl)methylideneamino]morpholine-4-carbothioamide
2-[4-[[[4-[2-[(4-chlorophenyl)amino]-1,3-thiazol-4-yl]phenyl]carbonylhydrazinylidene]methyl]phenoxy]ethanoic acid 2-[4-[[[[4-[2-(4-chloroanilino)-4-thiazolyl]phenyl]-oxomethyl]hydrazinylidene]methyl]phenoxy]acetic acid SMR000273648 cid_3143384 2-[4-[[[4-[2-(4-chloroanilino)-1,3-thiazol-4-yl]benzoyl]hydrazinylidene]methyl]phenoxy]acetic acid BDBM75323 MLS000703184 2-[4-[[[4-[2-(4-chloroanilino)thiazol-4-yl]benzoyl]hydrazono]methyl]phenoxy]acetic acid
3-[4-[4-(3-chlorophenyl)piperazin-1-yl]-4-oxidanylidene-butyl]-2-sulfanylidene-1H-quinazolin-4-one SMR000131184 3-[4-[4-(3-chlorophenyl)-1-piperazinyl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-[4-(3-chlorophenyl)piperazin-1-yl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-[4-(3-chlorophenyl)piperazino]-4-keto-butyl]-2-thioxo-1H-quinazolin-4-one BDBM40196 MLS000520775 cid_4177562
N-(2,6-Dimethoxy-pyrimidin-4-yl)-4-[4-(4-methoxy-phenyl)-thiazol-2-ylamino]-benzenesulfonamide cid_12004705 N-(2,6-dimethoxypyrimidin-4-yl)-4-[[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]amino]benzenesulfonamide;hydrobromide BDBM61499 N-(2,6-dimethoxy-4-pyrimidinyl)-4-[[4-(4-methoxyphenyl)-2-thiazolyl]amino]benzenesulfonamide;hydrobromide N-(2,6-dimethoxypyrimidin-4-yl)-4-[[4-(4-methoxyphenyl)thiazol-2-yl]amino]benzenesulfonamide;hydrobromide SMR000171879 MLS000555028
SMR000124178 4-[[3-[(4-methylphenyl)carbamoyl]-4-piperidin-1-yl-phenyl]amino]-4-oxidanylidene-butanoic acid cid_1080143 N-(4-Piperidin-1-yl-3-p-tolylcarbamoyl-phenyl)-succinamic acid 4-[3-[(4-methylanilino)-oxomethyl]-4-(1-piperidinyl)anilino]-4-oxobutanoic acid 4-[3-[(4-methylphenyl)carbamoyl]-4-piperidin-1-ylanilino]-4-oxobutanoic acid MLS000123596 BDBM59786 4-keto-4-[4-piperidino-3-(p-tolylcarbamoyl)anilino]butyric acid
[4-(4-chlorophenyl)piperazino]-[1-(3,5-dimethylisoxazol-4-yl)sulfonyl-4-piperidyl]methanone cid_3240304 [4-(4-chlorophenyl)-1-piperazinyl]-[1-[(3,5-dimethyl-4-isoxazolyl)sulfonyl]-4-piperidinyl]methanone [4-(4-chlorophenyl)piperazin-1-yl]-[1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl]methanone MLS000091464 1-(4-chlorophenyl)-4-({1-[(3,5-dimethylisoxazol-4-yl)sulfonyl]piperidin-4-yl}carbonyl)piperazine BDBM89668 SMR000026019
cid_16193041 N-[2-(4-ethylpiperazin-1-yl)-4-methyl-quinolin-6-yl]-4-(4-fluorophenyl)piperazine-1-carbothioamide BDBM78773 N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-4-(4-fluorophenyl)piperazine-1-carbothioamide SMR000308778 MLS000730502 N-[2-(4-ethylpiperazino)-4-methyl-6-quinolyl]-4-(4-fluorophenyl)piperazine-1-carbothioamide N-[2-(4-ethyl-1-piperazinyl)-4-methyl-6-quinolinyl]-4-(4-fluorophenyl)-1-piperazinecarbothioamide
cid_3245224 SMR000026030 MLS000091475 BDBM44198 [1-(3,5-dimethylisoxazol-4-yl)sulfonyl-4-piperidyl]-[4-(4-fluorophenyl)piperazino]methanone [1-[(3,5-dimethyl-4-isoxazolyl)sulfonyl]-4-piperidinyl]-[4-(4-fluorophenyl)-1-piperazinyl]methanone [1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]piperidin-4-yl]-[4-(4-fluorophenyl)piperazin-1-yl]methanone 1-({1-[(3,5-dimethylisoxazol-4-yl)sulfonyl]piperidin-4-yl}carbonyl)-4-(4-fluorophenyl)piperazine
(2,6-dimethoxy-4-morpholin-4-ylcarbothioyl-phenyl) 2-(4-fluorophenyl)ethanoate SMR000229209 2,6-dimethoxy-4-(4-morpholinylcarbothioyl)phenyl (4-fluorophenyl)acetate 2-(4-fluorophenyl)acetic acid [2,6-dimethoxy-4-(morpholine-4-carbothioyl)phenyl] ester [2,6-dimethoxy-4-(morpholine-4-carbothioyl)phenyl] 2-(4-fluorophenyl)acetate MLS000698939 2-(4-fluorophenyl)acetic acid [2,6-dimethoxy-4-[4-morpholinyl(sulfanylidene)methyl]phenyl] ester cid_1229341 BDBM44221
(2-methoxy-4-morpholin-4-ylcarbothioyl-phenyl) 2-(4-fluorophenyl)ethanoate MLS000676807 BDBM44077 cid_1306851 2-(4-fluorophenyl)acetic acid [2-methoxy-4-(morpholine-4-carbothioyl)phenyl] ester SMR000271817 2-(4-fluorophenyl)acetic acid [2-methoxy-4-[4-morpholinyl(sulfanylidene)methyl]phenyl] ester [2-methoxy-4-(morpholine-4-carbothioyl)phenyl] 2-(4-fluorophenyl)acetate 2-methoxy-4-(4-morpholinylcarbonothioyl)phenyl (4-fluorophenyl)acetate
(4-ethylphenyl)[4-(4-ethylpiperazin-1-yl)-6-methoxyquinolin-3-yl]methanone BDBM69290 MLS000686703 SMR000339745 (4-ethylphenyl)-[4-(4-ethylpiperazin-1-yl)-6-methoxy-quinolin-3-yl]methanone (4-ethylphenyl)-[4-(4-ethylpiperazin-1-yl)-6-methoxyquinolin-3-yl]methanone (4-ethylphenyl)-[4-(4-ethylpiperazino)-6-methoxy-3-quinolyl]methanone (4-ethylphenyl)-[4-(4-ethyl-1-piperazinyl)-6-methoxy-3-quinolinyl]methanone cid_5640144
(E)-4-oxo-4-(4-phenyl-1-piperazinyl)-2-butenoic acid methyl ester MLS000756128 (E)-4-keto-4-(4-phenylpiperazino)but-2-enoic acid methyl ester SMR000230156 methyl (E)-4-oxidanylidene-4-(4-phenylpiperazin-1-yl)but-2-enoate cid_851903 BDBM59463 methyl (E)-4-oxo-4-(4-phenylpiperazin-1-yl)but-2-enoate methyl 4-oxo-4-(4-phenyl-1-piperazinyl)-2-butenoate
1-(4-nitrophenyl)-3-[4-(pyridin-4-ylmethyl)anilino]propan-1-one BDBM34875 1-(4-nitrophenyl)-3-[4-(pyridin-4-ylmethyl)anilino]-1-propanone MLS000663673 1-(4-nitrophenyl)-3-{[4-(4-pyridinylmethyl)phenyl]amino}-1-propanone 1-(4-nitrophenyl)-3-[4-(4-pyridylmethyl)anilino]propan-1-one cid_1287136 SMR000292952 1-(4-nitrophenyl)-3-[[4-(pyridin-4-ylmethyl)phenyl]amino]propan-1-one
2-[4-[4-(4-bromophenyl)pyrimidin-2-yl]phenoxy]acetic acid methyl ester cid_1475120 SMR000550041 BDBM94043 methyl 2-[4-[4-(4-bromophenyl)pyrimidin-2-yl]phenoxy]ethanoate methyl 2-[4-[4-(4-bromophenyl)pyrimidin-2-yl]phenoxy]acetate methyl 2-{4-[4-(4-bromophenyl)-2-pyrimidinyl]phenoxy}acetate 2-[4-[4-(4-bromophenyl)-2-pyrimidinyl]phenoxy]acetic acid methyl ester MLS001166188
4-[2-[[4-(dimethylamino)benzyl]amino]ethyl]-2,2-dimethyl-tetrahydropyran-4-ol 4-[2-[[4-(dimethylamino)phenyl]methylamino]ethyl]-2,2-dimethyl-oxan-4-ol BDBM37959 4-[2-[[4-(dimethylamino)phenyl]methylamino]ethyl]-2,2-dimethyloxan-4-ol 4-[2-[[4-(dimethylamino)phenyl]methylamino]ethyl]-2,2-dimethyl-4-oxanol 4-[2-(4-Dimethylamino-benzylamino)-ethyl]-2,2-dimethyl-tetrahydro-pyran-4-ol cid_646846 MLS000030931 SMR000011103
4-[4-(4-fluorophenyl)piperazin-1-yl]carbonyl-1-[2-(4-methylphenyl)ethyl]pyrrolidin-2-one MLS000521153 4-[4-(4-fluorophenyl)piperazine-1-carbonyl]-1-[2-(4-methylphenyl)ethyl]pyrrolidin-2-one cid_3612501 4-[4-(4-fluorophenyl)piperazine-1-carbonyl]-1-[2-(p-tolyl)ethyl]-2-pyrrolidone BDBM73413 SMR000131562 4-[[4-(4-fluorophenyl)-1-piperazinyl]-oxomethyl]-1-[2-(4-methylphenyl)ethyl]-2-pyrrolidinone
5-[4-(4-methoxyphenyl)piperazin-1-yl]-2-(phenylmethyl)-1,3-oxazole-4-carbonitrile BDBM63021 5-[4-(4-methoxyphenyl)-1-piperazinyl]-2-(phenylmethyl)-4-oxazolecarbonitrile MLS000558480 cid_1843619 2-benzyl-5-[4-(4-methoxyphenyl)piperazin-1-yl]-1,3-oxazole-4-carbonitrile 2-benzyl-5-[4-(4-methoxyphenyl)piperazino]oxazole-4-carbonitrile 2-Benzyl-5-[4-(4-methoxy-phenyl)-piperazin-1-yl]-oxazole-4-carbonitrile SMR000148996
BDBM43697 3-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-2-sulfanylidene-imidazolidin-4-one 3-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-2-thioxo-4-imidazolidinone 3-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-2-sulfanylideneimidazolidin-4-one 3-[4-(4-methoxyphenyl)thiazol-2-yl]-2-thioxo-4-imidazolidinone MLS000578852 cid_898321 3-[4-(4-methoxyphenyl)-2-thiazolyl]-2-sulfanylidene-4-imidazolidinone SMR000197838
BDBM82778 N-(4-fluorophenyl)-4-(3-methyl-4-oxo-1-phthalazinyl)benzamide N-(4-fluorophenyl)-4-(4-keto-3-methyl-phthalazin-1-yl)benzamide MLS000625051 N-(4-fluorophenyl)-4-(3-methyl-4-oxidanylidene-phthalazin-1-yl)benzamide N-(4-fluorophenyl)-4-(3-methyl-4-oxo-3,4-dihydro-1-phthalazinyl)benzamide cid_1999173 N-(4-fluorophenyl)-4-(3-methyl-4-oxophthalazin-1-yl)benzamide SMR000293840
MLS000326998 (4-chlorophenyl)-[4-[[(2,4-dichlorophenyl)thio]methyl]-4-hydroxy-piperidino]methanone (4-chlorophenyl)-[4-[[(2,4-dichlorophenyl)thio]methyl]-4-hydroxy-1-piperidinyl]methanone (4-chlorophenyl)-[4-[(2,4-dichlorophenyl)sulfanylmethyl]-4-oxidanyl-piperidin-1-yl]methanone BDBM67903 cid_1489029 (4-chlorophenyl)-[4-[(2,4-dichlorophenyl)sulfanylmethyl]-4-hydroxypiperidin-1-yl]methanone (4-chlorophenyl)(4-{[(2,4-dichlorophenyl)sulfanyl]methyl}-4-hydroxypiperidino)methanone SMR000179615
MLS000540204 SMR000162356 4-chloro-N-[[4-[(4-methyl-1-piperazinyl)sulfonyl]anilino]-sulfanylidenemethyl]benzamide 4-chloro-N-[[4-(4-methylpiperazin-1-yl)sulfonylphenyl]carbamothioyl]benzamide 4-chloro-N-[[4-(4-methylpiperazino)sulfonylphenyl]thiocarbamoyl]benzamide cid_4778204 4-chloranyl-N-[[4-(4-methylpiperazin-1-yl)sulfonylphenyl]carbamothioyl]benzamide BDBM50145 N-(4-chlorobenzoyl)-N'-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}thiourea
N'-(4-chlorobenzoyl)-1-(4-fluorophenyl)-4-keto-pyridazine-3-carbohydrazide N'-(4-chlorobenzoyl)-1-(4-fluorophenyl)-4-oxopyridazine-3-carbohydrazide N'-[(4-chlorophenyl)-oxomethyl]-1-(4-fluorophenyl)-4-oxo-3-pyridazinecarbohydrazide BDBM78919 cid_2745061 SMR000461475 N'3-(4-chlorobenzoyl)-1-(4-fluorophenyl)-4-oxo-1,4-dihydropyridazine-3-carbohydrazide N'-(4-chlorophenyl)carbonyl-1-(4-fluorophenyl)-4-oxidanylidene-pyridazine-3-carbohydrazide MLS000833956
N-[1-[(4-chlorophenyl)methyl]-3,5-dimethyl-pyrazol-4-yl]-4-nitro-benzamide N-[1-(4-chlorobenzyl)-3,5-dimethyl-pyrazol-4-yl]-4-nitro-benzamide N-[1-[(4-chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-4-nitrobenzamide cid_1244053 N-[1-(4-chlorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-4-nitrobenzamide BDBM78184 N-[1-[(4-chlorophenyl)methyl]-3,5-dimethyl-4-pyrazolyl]-4-nitrobenzamide MLS000583238 SMR000201072
N-[3-chloro-4-[4-(4-propoxybenzoyl)piperazino]phenyl]propionamide N-{3-chloro-4-[4-(4-propoxybenzoyl)-1-piperazinyl]phenyl}propanamide N-[3-chloro-4-[4-(4-propoxybenzoyl)piperazin-1-yl]phenyl]propanamide N-[3-chloranyl-4-[4-(4-propoxyphenyl)carbonylpiperazin-1-yl]phenyl]propanamide N-[3-chloro-4-[4-[oxo-(4-propoxyphenyl)methyl]-1-piperazinyl]phenyl]propanamide BDBM89738 MLS000052063 SMR000076902 cid_2956580
N-[4-(dimethylamino)phenyl]-2-[4-(4-fluorobenzoyl)piperidin-1-yl]acetamide BDBM58949 N-[4-(dimethylamino)phenyl]-2-[4-(4-fluorobenzoyl)piperidino]acetamide MLS000033552 cid_656006 N-[4-(dimethylamino)phenyl]-2-[4-(4-fluorophenyl)carbonylpiperidin-1-yl]ethanamide N-(4-Dimethylamino-phenyl)-2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-acetamide SMR000007080 N-[4-(dimethylamino)phenyl]-2-[4-[(4-fluorophenyl)-oxomethyl]-1-piperidinyl]acetamide
SMR000269003 MLS000666083 BDBM43523 ethyl 4-[4-[(4-chlorophenyl)sulfanylmethyl]benzoyl]piperazine-1-carboxylate 4-[4-[[(4-chlorophenyl)thio]methyl]benzoyl]piperazine-1-carboxylic acid ethyl ester ethyl 4-(4-{[(4-chlorophenyl)thio]methyl}benzoyl)-1-piperazinecarboxylate ethyl 4-[4-[(4-chlorophenyl)sulfanylmethyl]phenyl]carbonylpiperazine-1-carboxylate 4-[[4-[[(4-chlorophenyl)thio]methyl]phenyl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester cid_2896535
[1-[[4-(2-furanyl)phenyl]methyl]-4-(phenylmethyl)-4-piperidinyl]methanol [4-benzyl-1-[[4-(furan-2-yl)phenyl]methyl]piperidin-4-yl]methanol cid_16191622 {4-benzyl-1-[4-(2-furyl)benzyl]piperidin-4-yl}methanol MLS000732752 [4-benzyl-1-[4-(2-furyl)benzyl]-4-piperidyl]methanol BDBM69177 [1-[[4-(furan-2-yl)phenyl]methyl]-4-(phenylmethyl)piperidin-4-yl]methanol SMR000319112
[1-[[4-(difluoromethoxy)phenyl]methyl]-4-(2-phenylethyl)-4-piperidinyl]methanol [1-[[4-(difluoromethoxy)phenyl]methyl]-4-(2-phenylethyl)piperidin-4-yl]methanol BDBM59491 cid_16190952 MLS000733883 [1-[4-(difluoromethoxy)benzyl]-4-phenethyl-4-piperidyl]methanol [1-[[4-[bis(fluoranyl)methoxy]phenyl]methyl]-4-(2-phenylethyl)piperidin-4-yl]methanol SMR000317231 [1-[4-(difluoromethoxy)benzyl]-4-(2-phenylethyl)piperidin-4-yl]methanol
cid_2766344 methyl 1-(4-{3-[4-(4-nitrophenyl)piperazino]propoxy}benzyl)-4-piperidinecarboxylate MLS000763507 SMR000336850 1-[[4-[3-[4-(4-nitrophenyl)-1-piperazinyl]propoxy]phenyl]methyl]-4-piperidinecarboxylic acid methyl ester methyl 1-[[4-[3-[4-(4-nitrophenyl)piperazin-1-yl]propoxy]phenyl]methyl]piperidine-4-carboxylate 1-[4-[3-[4-(4-nitrophenyl)piperazino]propoxy]benzyl]isonipecotic acid methyl ester BDBM74521
cid_3244473 1-[4-[2-(4-bromanylphenoxy)ethanoyl]piperazin-1-yl]-2-(4-methoxyphenoxy)ethanone 1-[4-[2-(4-bromophenoxy)acetyl]piperazino]-2-(4-methoxyphenoxy)ethanone MLS000043197 1-[(4-bromophenoxy)acetyl]-4-[(4-methoxyphenoxy)acetyl]piperazine SMR000019818 BDBM53701 1-[4-[2-(4-bromophenoxy)acetyl]piperazin-1-yl]-2-(4-methoxyphenoxy)ethanone 1-[4-[2-(4-bromophenoxy)-1-oxoethyl]-1-piperazinyl]-2-(4-methoxyphenoxy)ethanone
cid_646198 N-[1-(4-Acetylamino-benzenesulfonyl)-4-(3-fluoro-phenyl)-piperidin-4-yl]-acetamide N-[4-[4-acetamido-4-(3-fluorophenyl)piperidin-1-yl]sulfonylphenyl]ethanamide SMR000000405 BDBM89517 MLS000075928 N-[4-[4-acetamido-4-(3-fluorophenyl)piperidino]sulfonylphenyl]acetamide N-[4-[[4-acetamido-4-(3-fluorophenyl)-1-piperidinyl]sulfonyl]phenyl]acetamide N-[4-[4-acetamido-4-(3-fluorophenyl)piperidin-1-yl]sulfonylphenyl]acetamide
cid_653359 4-[4-[2-(4-fluorobenzyl)tetrazol-5-yl]benzyl]morpholine SMR000006661 BDBM93705 MLS000068019 4-[[4-[2-[(4-fluorophenyl)methyl]tetrazol-5-yl]phenyl]methyl]morpholine 4-{4-[2-(4-Fluoro-benzyl)-2H-tetrazol-5-yl]-benzyl}-morpholine 4-[[4-[2-[(4-fluorophenyl)methyl]-1,2,3,4-tetrazol-5-yl]phenyl]methyl]morpholine 4-[[4-[2-[(4-fluorophenyl)methyl]-5-tetrazolyl]phenyl]methyl]morpholine
(4-chlorophenyl)-thiomorpholino-methanone MLS000030070 SMR000010181 (4-Chloro-phenyl)-thiomorpholin-4-yl-methanone BDBM87597 (4-chlorophenyl)-thiomorpholin-4-yl-methanone cid_587190 (4-chlorophenyl)-thiomorpholin-4-ylmethanone
6-(4-t-butylphenyl)-2-(4-morpholin-4-yl)pyran-4-one CHEMBL102529 2-(4-tert-Butyl-phenyl)-6-morpholin-4-yl-pyran-4-one BDBM50132358
BDBM276042 US9896436, Example 4 US10071984, Example 4 US10174003, Example 4 2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-methylimidazol-4-yl]-4-(1H-triazol-4-yl)pyridine
BDBM50029759 2-{4-Carboxy-4-[4-carboxy-4-(4-carboxy-4-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-pentanedioic acid CHEMBL145221
MLS000547365 SMR000180264 4-[4-(2-quinolyl)phenyl]morpholine 4-[4-(2-quinolinyl)phenyl]morpholine BDBM95265 2-(4-morpholinophenyl)quinoline 4-(4-quinolin-2-ylphenyl)morpholine cid_1472976
MLS001207020 SMR000516584 4-Morpholin-4-yl-[1,2]naphthoquinone BDBM54416 4-morpholin-4-ylnaphthalene-1,2-dione 4-(4-morpholinyl)naphthalene-1,2-dione 4-morpholino-1,2-naphthoquinone cid_272529
2-[4-(4-fluorophenyl)piperazin-1-yl]-N-[(4-methoxyphenyl)methyl]acetamide MLS001165743 2-[4-(4-fluorophenyl)piperazino]-N-(4-methoxybenzyl)acetamide SMR000550470 cid_1142129 2-[4-(4-fluorophenyl)piperazin-1-yl]-N-[(4-methoxyphenyl)methyl]ethanamide BDBM90867 2-[4-(4-fluorophenyl)-1-piperazinyl]-N-[(4-methoxyphenyl)methyl]acetamide 2-[4-(4-fluorophenyl)piperazino]-N-p-anisyl-acetamide
2-[[4-(4-methylphenyl)sulfonylpiperazin-1-yl]methyl]-4-propan-2-ylphenol 2-[[4-(4-methylphenyl)sulfonylpiperazin-1-yl]methyl]-4-propan-2-yl-phenol MLS000084752 BDBM45380 SMR000019098 2-[[4-(4-methylphenyl)sulfonyl-1-piperazinyl]methyl]-4-propan-2-ylphenol 4-isopropyl-2-[(4-tosylpiperazino)methyl]phenol 4-Isopropyl-2-[4-(toluene-4-sulfonyl)-piperazin-1-ylmethyl]-phenol cid_1040497
5-chloro-4-(4-methoxyphenoxy)-2-(4-methylphenyl)pyridazin-3-one 5-chloro-4-(4-methoxyphenoxy)-2-(p-tolyl)pyridazin-3-one BDBM62088 MLS000326740 5-chloro-4-(4-methoxyphenoxy)-2-(4-methylphenyl)-3(2H)-pyridazinone cid_1479652 5-chloro-4-(4-methoxyphenoxy)-2-(4-methylphenyl)-3-pyridazinone 5-chloranyl-4-(4-methoxyphenoxy)-2-(4-methylphenyl)pyridazin-3-one SMR000179329
6-(4-methoxyphenyl)-3-p-toluoyl-1H-pyridazin-4-one 6-(4-methoxyphenyl)-3-(4-methylbenzoyl)-1H-pyridazin-4-one MLS000674480 6-(4-methoxyphenyl)-3-[(4-methylphenyl)-oxomethyl]-1H-pyridazin-4-one SMR000313683 BDBM47667 cid_1507586 [4-hydroxy-6-(4-methoxyphenyl)pyridazin-3-yl](4-methylphenyl)methanone 6-(4-methoxyphenyl)-3-(4-methylphenyl)carbonyl-1H-pyridazin-4-one
MLS000099600 cid_2165175 SMR000071356 4-(4-chloro-2-methylphenoxy)-1-morpholin-4-ylbutan-1-one 4-[4-(4-chloro-2-methylphenoxy)butanoyl]morpholine 4-(4-chloro-2-methylphenoxy)-1-(4-morpholinyl)-1-butanone 4-(4-chloro-2-methyl-phenoxy)-1-morpholino-butan-1-one 4-(4-chloranyl-2-methyl-phenoxy)-1-morpholin-4-yl-butan-1-one BDBM62751
4-(2-(4-fluorophenoxy)-4-methylphenyl)piperidine CHEMBL574347 BDBM50299812
4-Phenyl-4-(4-trifluoromethyl-benzyloxymethyl)-piperidine CHEMBL444339 BDBM50067975
4-[4-(benzhydryloxy)piperidino]butyl 4-fluorobenzoate BDBM50219245 CHEMBL229001
4-[4-(benzhydryloxy)piperidino]butyl 4-isopropylbenzoate CHEMBL229051 BDBM50219239
4-[4-(benzhydryloxy)piperidino]butyl-4-chlorobenzoate BDBM50219232 CHEMBL229000
4-[4-(benzhydryloxy)piperidino]butyl-4-nitrobenzoate CHEMBL390809 BDBM50219237
4-[4-(benzyloxy)piperidino]butyl-4-chlorobenzoate CHEMBL389048 BDBM50219244
4-[4-(benzyloxy)piperidino]butyl-4-nitrobenzoate CHEMBL228301 BDBM50219236
4-hydroxyquinazoline BDBM27504 CHEMBL266540 quinazolin-4-ol 4-HQN
BDBM103877 US10968221, Example 4 US9695167, 4 US10125133, Example 4
BDBM168631 US9745328, Compound 4 US9079866, 4 US9884878, Compound 4
BDBM50247851 4-(4-Chlorophenyl)-5-(4-methoxyphenyl)isothiazole CHEMBL522624
BDBM50297214 CHEMBL562534 1-(4-chlorophenylsulfonyl)-4-phenylazepan-4-ol
BDBM50297215 1-(4-methoxyphenylsulfonyl)-4-phenylazepan-4-ol CHEMBL561076
BDBM50324612 CHEMBL1215665 4'-(Pyridin-4-ylmethyl)biphenyl-4-amine
CHEMBL1215664 BDBM50324611 4-[(4'-Hydroxybiphenyl-4-yl)methyl]pyridine
CHEMBL1215731 4'-(Pyridin-4-ylmethyl)biphenyl-4-carboxamide BDBM50324615
CHEMBL1215732 BDBM50324616 4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine
CHEMBL228303 4-[4-(benzyloxy)piperidino]butyl-4-isopropylbenzoate BDBM50219229
CHEMBL229105 BDBM50219230 4-[4-(benzyloxy)piperidino]butyl-4-fluorobenzoate
CHEMBL34712 4-bromophenylazophenol BDBM50111585 4-(4-Bromo-phenylazo)-phenol
CHEMBL491089 BDBM50247850 5-(4-Chlorophenyl)-4-(4-methoxyphenyl)isothiazole
CHEMBL562684 BDBM50297213 1-(4-ethylphenylsulfonyl)-4-phenylazepan-4-ol
Method #4 BDBM508759 US11071721, Example 4 US11607396, Example 4
N-(4-Chlorophenyl)-4-methylpiperazine-1-carboxamide (4) BDBM189346
US10155002, Compound 4 BDBM172000 US9090562, 4 US11052093, Compound 4
US10383871, Example 4 BDBM155358 US9006269, 4 US10918640, Example 4
US10479788, Example 4 US9409907, 4 US11046688, Example 4 BDBM241162
US10513499, Compound 4 US9708272, 4 BDBM261521 US11254644, Compound 4
US10723709, Example 4 US11312693, Example 4 BDBM123100 US8735395, 4
US10736881, Compound 4 US10201527, Compound 4 BDBM38233 US8551988, 4
US11697648, Example 4 BDBM250094 US10501411, Example 4 US9452980, 4
US9096596, 4 BDBM173252 US10323032, Example 4 US9604982, Example 4
US9260440, 4 US10501467, Example 4 BDBM207559 US9617273, Example 4
US9321760, 4 BDBM224327 US9662330, Compound 4 US10080750, Compound 4
US9434719, 4 BDBM247481 US9688672, Example 4 US10112931, Example 4
US9540373, 4 USRE47636, Example 4 BDBM201015 US9879026, Example 4
US9822102, Example 4 BDBM246099 US9434690, 4 US10183932, Example 4
US9918985, Example 4 US8865911, 4 US10231967, Example 4 BDBM136914
MLS000693792 SMR000319752 ethyl 4-(4-methoxybenzyl)-1-(propylsulfonyl)piperidine-4-carboxylate 4-p-anisyl-1-propylsulfonyl-isonipecotic acid ethyl ester BDBM94235 ethyl 4-[(4-methoxyphenyl)methyl]-1-propylsulfonyl-piperidine-4-carboxylate ethyl 4-[(4-methoxyphenyl)methyl]-1-propylsulfonylpiperidine-4-carboxylate 4-[(4-methoxyphenyl)methyl]-1-propylsulfonyl-4-piperidinecarboxylic acid ethyl ester cid_16191946
US10548896, Example 4 US9771329, Example 4 4-[2-(4-amino-piperidin-1-yl)-1- methyl-5-(6-methylpyridin-3-yl)- 6-oxo-1,6-dihydro-pyrimidin-4- yl]-benzonitrile US9573930, Example 4 BDBM283199 US10207999, Example 4 US9776974, Example 4 US10849898, Example 4 US10960005, Example 4 US10023543, Example 4 US11084793, Example 4 US10328077, Example 4
[5-(4-chlorophenyl)sulfonyl-4-thiadiazolyl]-(4-morpholinyl)methanone MLS000707180 [5-(4-chlorophenyl)sulfonyl-1,2,3-thiadiazol-4-yl]-morpholin-4-yl-methanone cid_1487004 {5-[(4-chlorophenyl)sulfonyl]-1,2,3-thiadiazol-4-yl}(morpholino)methanone [5-(4-chlorophenyl)sulfonylthiadiazol-4-yl]-morpholino-methanone SMR000334562 [5-(4-chlorophenyl)sulfonylthiadiazol-4-yl]-morpholin-4-ylmethanone BDBM43273
cid_1486985 SMR000334558 [5-(4-chlorophenyl)sulfinyl-1,2,3-thiadiazol-4-yl]-morpholin-4-yl-methanone [5-(4-chlorophenyl)sulfinyl-4-thiadiazolyl]-(4-morpholinyl)methanone BDBM60659 MLS000707175 [5-(4-chlorophenyl)sulfinylthiadiazol-4-yl]-morpholino-methanone {5-[(4-chlorophenyl)sulfinyl]-1,2,3-thiadiazol-4-yl}(morpholino)methanone [5-(4-chlorophenyl)sulfinylthiadiazol-4-yl]-morpholin-4-ylmethanone
1-(4-(4-chlorophenyl)thiazol-2-yl)-2-(4-methylcyclohexylidene)hydrazine CHEMBL248049 BDBM50326643 4-(4-chlorophenyl)-2-(2-(4-methylcyclohexylidene)hydrazinyl)thiazole
2-(4-methoxyphenyl)-4H-chromen-4-one 4'-methoxyflavone BDBM50310189 4-methoxy flavone CHEMBL16312 cid_77793 2-(4-Methoxy-phenyl)-chromen-4-one
4-(4-(4-chlorophenylamino)phthalazin-1-yl)-N-methylbenzamide 4-[4-(4-Chloro-phenylamino)-phthalazin-1-yl]-N-methyl-benzamide CHEMBL196939 BDBM50173013
4-(4-Butoxy-benzenesulfonyl)-1-ethyl-piperidine-4-carboxylic acid hydroxyamide 4-(4-butoxyphenylsulfonyl)-1-ethyl-N-hydroxypiperidine-4-carboxamide CHEMBL79111 BDBM50128635
4-(4-butoxyphenylsulfonyl)-1-butyl-N-hydroxypiperidine-4-carboxamide BDBM50128666 4-(4-Butoxy-benzenesulfonyl)-1-butyl-piperidine-4-carboxylic acid hydroxyamide CHEMBL420023
5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-1H-imidazole CHEMBL43165 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-imidazole BDBM50286951
BDBM15567 DPP-4 ligand 9 (2R,3S)-2-[4-(4-fluorophenyl)phenyl]-N,N,3-trimethyl-4-(morpholin-4-yl)-4-oxobutanamide
BDBM365316 US10533001, Example 4 US9868729, Example 4 2-(4-(4- acetylpiperazin-1- yl)phenylamino)-4- (cyclopentylamino) pyrimidine-5- carboxamide US11414410, Example 4
BDBM50084799 4-{4-[4-(Quinolin-2-ylmethoxy)-benzylcarbamoyl]-phenyl}-butyric acid 4-(4-(4-(quinolin-2-ylmethoxy)benzylcarbamoyl)phenyl)butanoic acid CHEMBL128151
BDBM50128661 N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-methylpiperidine-4-carboxamide 4-(4-Methoxy-benzenesulfonyl)-1-methyl-piperidine-4-carboxylic acid hydroxyamide CHEMBL312585
BDBM50128665 CHEMBL419648 4-(4-butoxyphenylsulfonyl)-N-hydroxy-1-methylpiperidine-4-carboxamide 4-(4-Butoxy-benzenesulfonyl)-1-methyl-piperidine-4-carboxylic acid hydroxyamide
BDBM50154664 CHEMBL185999 4N-(4-chlorophenyl)-4N-methyl-1-[4-(4-{4-[4-chloro(methyl)anilino]-1-pyridiniumylmethyl}phenyl)benzyl]-4-pyridiniumamine; dibromide
BDBM50156500 CHEMBL189552 8-(4-hydroxymethylphenyl)-2-morpholin-4-ylchromen-4-one 8-(4-Hydroxymethyl-phenyl)-2-morpholin-4-yl-chromen-4-one
BDBM76771 4-(4-fluoroanilino)naphthalene-1,2-dione MLS001360406 4-[(4-fluorophenyl)amino]naphthalene-1,2-dione SMR001224032 4-(4-fluoroanilino)-1,2-naphthoquinone cid_4454203
CHEMBL187905 BDBM50169756 4-methyl-2-(4-methylbenzoyl)phenyl 4-methylbenzoate 4-Methyl-benzoic acid 4-methyl-2-(4-methyl-benzoyl)-phenyl ester
CHEMBL222160 cis-4-(3-(4-(4-fluorophenoxy)cyclohexyl)ureido)benzoic acid 4-{3-[4-(4-fluoro-phenoxy)-cyclohexyl]-ureido}-benzoic acid BDBM50194496
CHEMBL309492 BDBM50128667 1-Benzyl-4-(4-butoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide 1-benzyl-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide
IMMEPIP 4-(1H-Imidazol-4-ylmethyl)-piperidine CHEMBL18661 BDBM50175834 4-((1H-imidazol-4-yl)methyl)piperidine 4-(3H-Imidazol-4-ylmethyl)-piperidine
MLS001360404 SMR001224012 cid_3633677 4-[(4-ethylphenyl)amino]naphthalene-1,2-dione 4-(4-ethylanilino)-1,2-naphthoquinone 4-(4-ethylanilino)naphthalene-1,2-dione BDBM83984
N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-phenethylpiperidine-4-carboxamide 4-(4-Methoxy-benzenesulfonyl)-1-phenethyl-piperidine-4-carboxylic acid hydroxyamide BDBM50128646 CHEMBL310057
US9663496, Compound 4 N-(1-(4- cyanobenzoyl)piperidin- 4-yl)-5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)picolinamide US10377742, Compound 4 BDBM327865
cid_7958287 4-(4-ethoxyphenoxy)-N-[2-(4-methoxyphenyl)ethyl]butanamide 4-(4-ethoxyphenoxy)-N-[2-(4-methoxyphenyl)ethyl]butyramide SMR000688837 BDBM74129 MLS001143034
3,5-dimethyl-4-[4-(4-nitrophenyl)piperazino]sulfonyl-isoxazole BDBM74062 cid_3747730 MLS000950595 3,5-dimethyl-4-[[4-(4-nitrophenyl)-1-piperazinyl]sulfonyl]isoxazole 3,5-dimethyl-4-[4-(4-nitrophenyl)piperazin-1-yl]sulfonyl-1,2-oxazole SMR000622295
MLS001196707 BDBM64088 2-(4-tert-butylphenyl)-4-(4-methylpiperazin-1-yl)quinazoline;hydrochloride 2-(4-tert-butylphenyl)-4-(4-methyl-1-piperazinyl)quinazoline;hydrochloride 2-(4-tert-butylphenyl)-4-(4-methylpiperazino)quinazoline;hydrochloride cid_24748018 SMR000556085
N-(4-ethylphenyl)-4-methyl-3-(morpholine-4-carbonyl)benzenesulfonamide N-(4-ethylphenyl)-4-methyl-3-[4-morpholinyl(oxo)methyl]benzenesulfonamide cid_6462016 N-(4-ethylphenyl)-4-methyl-3-morpholin-4-ylcarbonyl-benzenesulfonamide BDBM61380 MLS001034740 SMR000670793
SMR000141801 4-[4-(4-tert-butylphenoxy)-6-methylpyrimidin-2-yl]morpholine 4-[4-(4-tert-butylphenoxy)-6-methyl-2-pyrimidinyl]morpholine cid_697271 BDBM80771 4-[4-(4-tert-butylphenoxy)-6-methyl-pyrimidin-2-yl]morpholine MLS000534369
[4-[[4-(dimethylamino)phenyl]-(4-nitrophenyl)methyl]phenyl]-dimethyl-amine SMR000528045 4-[[4-(dimethylamino)phenyl]-(4-nitrophenyl)methyl]-N,N-dimethyl-aniline 4-[[4-(dimethylamino)phenyl]-(4-nitrophenyl)methyl]-N,N-dimethylaniline cid_220490 BDBM55871 MLS000736496
cid_2877505 SMR000275083 MLS000715104 4-[[4-(4-methoxyphenyl)-2-thiazolyl]amino]phenol;hydrobromide 4-[[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]amino]phenol;hydrobromide BDBM49810 4-[[4-(4-methoxyphenyl)thiazol-2-yl]amino]phenol;hydrobromide CHEMBL1081480
cid_2985091 4-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine BDBM51953 4-(4-methoxyphenyl)-2-(4-methyl-1-piperazinyl)-6-(trifluoromethyl)pyrimidine 4-(4-methoxyphenyl)-2-(4-methylpiperazino)-6-(trifluoromethyl)pyrimidine SMR000022315 MLS000044538
cid_3235676 4-(4-fluorophenyl)-2-(4-methylpiperidino)-6-(trifluoromethyl)pyrimidine BDBM56969 4-(4-fluorophenyl)-2-(4-methyl-1-piperidinyl)-6-(trifluoromethyl)pyrimidine SMR000022313 MLS000044536 4-(4-fluorophenyl)-2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)pyrimidine
(Z)-4-[4-(dimethylamino)anilino]-4-oxobut-2-enoic acid cid_1555866 (Z)-4-[[4-(dimethylamino)phenyl]amino]-4-oxidanylidene-but-2-enoic acid BIM-0025763.P001 (Z)-4-[4-(dimethylamino)anilino]-4-oxo-2-butenoic acid BDBM42085 (Z)-4-[4-(dimethylamino)anilino]-4-keto-but-2-enoic acid
2-(4-methylphenoxy)-1-[4-(4-phenylphthalazin-1-yl)piperazin-1-yl]ethanone 1-{4-[(4-methylphenoxy)acetyl]-1-piperazinyl}-4-phenylphthalazine BDBM77209 SMR000143374 2-(4-methylphenoxy)-1-[4-(4-phenyl-1-phthalazinyl)-1-piperazinyl]ethanone 2-(4-methylphenoxy)-1-[4-(4-phenylphthalazin-1-yl)piperazino]ethanone cid_2951748 MLS000536337
2-(4-methylphenyl)-N-(pyridin-4-ylmethylideneamino)-4-quinazolinamine SMR000140404 cid_2846763 isonicotinaldehyde [2-(4-methylphenyl)-4-quinazolinyl]hydrazone MLS000532966 2-(4-methylphenyl)-N-(pyridin-4-ylmethylideneamino)quinazolin-4-amine [2-(p-tolyl)quinazolin-4-yl]-(4-pyridylmethyleneamino)amine BDBM48254 [2-(p-tolyl)quinazolin-4-yl]-[(E)-4-pyridylmethyleneamino]amine
2-benzyl-4-(4-methoxyanilino)-4-oxobutanoic acid MLS000031626 2-Benzyl-N-(4-methoxy-phenyl)-succinamic acid 4-[(4-methoxyphenyl)amino]-4-oxidanylidene-2-(phenylmethyl)butanoic acid BDBM59594 2-benzyl-4-keto-4-(p-anisidino)butyric acid SMR000010750 4-(4-methoxyanilino)-4-oxo-2-(phenylmethyl)butanoic acid cid_650723
4-[(4-aminophenyl)-(4-azanylidenecyclohexa-2,5-dien-1-ylidene)methyl]aniline MLS002701900 BDBM93926 4-[(4-aminophenyl)-(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]aniline [4-[(4-aminophenyl)-(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]phenyl]amine cid_11293 4-[(4-aminophenyl)-(4-imino-1-cyclohexa-2,5-dienylidene)methyl]aniline SMR001565485
4-chloro-N-[2-[4-(4-fluorophenyl)piperazino]cyclohexyl]benzenesulfonamide 4-chloranyl-N-[2-[4-(4-fluorophenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide SMR000625522 4-chloro-N-[2-[4-(4-fluorophenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide 4-chloro-N-[2-[4-(4-fluorophenyl)-1-piperazinyl]cyclohexyl]benzenesulfonamide BDBM91039 cid_23604963 MLS001116371
4-fluoro-N-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]benzenesulfonamide 4-fluoro-N-[4-(2-phenyl-4-thiazolyl)phenyl]benzenesulfonamide cid_1346843 4-fluoro-N-[4-(2-phenylthiazol-4-yl)phenyl]benzenesulfonamide MLS000574138 4-fluoranyl-N-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]benzenesulfonamide BDBM57413 SMR000195724
4-methoxy-N-[[4-[4-(phenylmethyl)piperazin-1-yl]carbonylphenyl]methyl]benzenesulfonamide N-[4-(4-benzylpiperazine-1-carbonyl)benzyl]-4-methoxy-benzenesulfonamide N-[[4-(4-benzylpiperazine-1-carbonyl)phenyl]methyl]-4-methoxybenzenesulfonamide MLS-0364353.0001 cid_20854208 4-methoxy-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide BDBM62201
4-methyl-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide N-[4-(4-benzylpiperazine-1-carbonyl)benzyl]-4-methyl-benzenesulfonamide cid_9551230 BDBM47530 SMR000132203 4-methyl-N-[[4-[4-(phenylmethyl)piperazin-1-yl]carbonylphenyl]methyl]benzenesulfonamide N-[[4-(4-benzylpiperazine-1-carbonyl)phenyl]methyl]-4-methylbenzenesulfonamide MLS000521795
BDBM43862 cid_3930725 Glycopeptide, 3 2-(aminocarbonylamino)-N-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-methylsulfanyl-butanamide N-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-(methylthio)-2-ureido-butyramide SMR000365182 2-(carbamoylamino)-N-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-(methylthio)butanamide 2-(carbamoylamino)-N-[4-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-methylsulfanylbutanamide MLS000774035
BDBM90981 4-chloro-N-[2-[4-(4-methoxyphenyl)-1-piperazinyl]cyclohexyl]benzenesulfonamide cid_23604968 4-chloro-N-[2-[4-(4-methoxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide MLS001116401 SMR000625525 4-chloro-N-[2-[4-(4-methoxyphenyl)piperazino]cyclohexyl]benzenesulfonamide 4-chloranyl-N-[2-[4-(4-methoxyphenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide
MLS000724491 4-[2-(4-chlorophenyl)-2-oxoethyl]-4-(3-phenylprop-2-ynyl)morpholin-4-ium cid_16193015 BDBM67272 SMR000306085 1-(4-chlorophenyl)-2-[4-(3-phenylprop-2-ynyl)-4-morpholin-4-iumyl]ethanone;bromide 1-(4-chlorophenyl)-2-[4-(3-phenylprop-2-ynyl)morpholin-4-ium-4-yl]ethanone;bromide
MLS000756458 2-nitro-4-[(6-nitroquinolin-4-yl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide BDBM50649 2-nitro-4-[(6-nitro-4-quinolinyl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide cid_5236119 SMR000528741 2-nitro-4-[(6-nitro-4-quinolyl)amino]-N-[4-(4-pyridylamino)phenyl]benzamide
N-(4-methylpyridin-2-yl)-4-thiophen-2-yl-oxane-4-carboxamide BDBM51816 N-(4-methylpyridin-2-yl)-4-thiophen-2-yloxane-4-carboxamide SMR000237271 MLS000696829 N-(4-methyl-2-pyridyl)-4-(2-thienyl)tetrahydropyran-4-carboxamide N-(4-methyl-2-pyridinyl)-4-thiophen-2-yl-4-oxanecarboxamide cid_12005896
[4-(4-bromophenyl)-1-piazthiol-4-ylsulfonyl-pyrazol-3-yl]amine MLS000052740 1-(2,1,3-benzothiadiazol-4-ylsulfonyl)-4-(4-bromophenyl)pyrazol-3-amine 1-(2,1,3-benzothiadiazol-4-ylsulfonyl)-4-(4-bromophenyl)-3-pyrazolamine cid_1258047 BDBM40293 1-(2,1,3-benzothiadiazol-4-ylsulfonyl)-4-(4-bromophenyl)-1H-pyrazol-3-amine SMR000082517
cid_1239154 1-[4-[4-(4-bromobenzoyl)piperazino]-3-fluoro-phenyl]ethanone SMR000105314 MLS000109371 1-[4-[4-(4-bromobenzoyl)piperazin-1-yl]-3-fluorophenyl]ethanone 1-[4-[4-[(4-bromophenyl)-oxomethyl]-1-piperazinyl]-3-fluorophenyl]ethanone 1-[4-[4-(4-bromophenyl)carbonylpiperazin-1-yl]-3-fluoranyl-phenyl]ethanone BDBM41480
(4-pyrrolidinosulfonylphenyl)-(4-tosylpiperazino)methanone SMR000519142 BDBM89384 [4-(4-methylphenyl)sulfonyl-1-piperazinyl]-[4-(1-pyrrolidinylsulfonyl)phenyl]methanone [4-(Pyrrolidine-1-sulfonyl)-phenyl]-[4-(toluene-4-sulfonyl)-piperazin-1-yl]-methanone MLS001205764 cid_1435354 [4-(4-methylphenyl)sulfonylpiperazin-1-yl]-(4-pyrrolidin-1-ylsulfonylphenyl)methanone
1-[2-[4-[(4-chlorophenyl)methoxy]phenyl]-4-cyano-5-oxazolyl]-4-piperidinecarboxamide BDBM40956 cid_664100 MLS000042015 1-[2-[4-[(4-chlorophenyl)methoxy]phenyl]-4-cyano-1,3-oxazol-5-yl]piperidine-4-carboxamide 1-[2-[4-(4-chlorobenzyl)oxyphenyl]-4-cyano-oxazol-5-yl]isonipecotamide SMR000044900
2-(4-ethylphenyl)-N-(1,2,4-triazol-4-yl)-4-quinolinecarboxamide 2-(4-ethylphenyl)-N-(1,2,4-triazol-4-yl)cinchoninamide cid_868748 2-(4-ethylphenyl)-N-4H-1,2,4-triazol-4-yl-4-quinolinecarboxamide MLS000532883 SMR000140321 2-(4-ethylphenyl)-N-(1,2,4-triazol-4-yl)quinoline-4-carboxamide BDBM48237
2-(4-methoxyphenyl)-3-(3-morpholin-4-ylpropyl)quinazolin-4-one 2-(4-methoxyphenyl)-3-(3-morpholinopropyl)quinazolin-4-one MLS000099961 SMR000081156 BDBM73342 cid_1249730 2-(4-methoxyphenyl)-3-[3-(4-morpholinyl)propyl]-4-quinazolinone 2-(4-methoxyphenyl)-3-[3-(4-morpholinyl)propyl]-4(3H)-quinazolinone
4-[4-(difluoromethyl)-6-(4-methylphenyl)-2-pyrimidinyl]morpholine BDBM95392 cid_2992799 SMR000297260 MLS000674309 4-[4-(difluoromethyl)-6-(4-methylphenyl)pyrimidin-2-yl]morpholine 4-[4-(difluoromethyl)-6-(p-tolyl)pyrimidin-2-yl]morpholine 4-[4-[bis(fluoranyl)methyl]-6-(4-methylphenyl)pyrimidin-2-yl]morpholine
4-chloro-N-(3-chloro-4-morpholino-phenyl)benzamide MLS000706164 BDBM81077 4-chloro-N-(3-chloro-4-morpholin-4-ylphenyl)benzamide 4-chloranyl-N-(3-chloranyl-4-morpholin-4-yl-phenyl)benzamide cid_1114260 4-chloro-N-[3-chloro-4-(4-morpholinyl)phenyl]benzamide SMR000288216
BDBM43601 1-(3-bromo-4-methoxybenzyl)-4-[(4-methylphenyl)sulfonyl]piperazine SMR000135524 1-[(3-bromo-4-methoxyphenyl)methyl]-4-(4-methylphenyl)sulfonylpiperazine 1-(3-bromo-4-methoxy-benzyl)-4-tosyl-piperazine MLS000530544 1-[(3-bromanyl-4-methoxy-phenyl)methyl]-4-(4-methylphenyl)sulfonyl-piperazine cid_1360988
cid_4637224 SMR000244157 N-[4-chloranyl-3-[(3-chlorophenyl)sulfamoyl]phenyl]-4-(4-methylphenyl)-4-oxidanylidene-butanamide MLS000339542 N-[4-chloro-3-[(3-chlorophenyl)sulfamoyl]phenyl]-4-(4-methylphenyl)-4-oxobutanamide N-[4-chloro-3-[(3-chlorophenyl)sulfamoyl]phenyl]-4-keto-4-(p-tolyl)butyramide BDBM45256
cid_661907 1-[(4-methylphenyl)methyl]-4-[4-(4-methylphenyl)-1-piperazinyl]pyrazolo[3,4-d]pyrimidine MLS-0002494.0001 1-(4-methylbenzyl)-4-[4-(p-tolyl)piperazino]pyrazolo[3,4-d]pyrimidine 1-[(4-methylphenyl)methyl]-4-[4-(4-methylphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine BDBM64822
4-(4-chlorophenyl)sulfanyl-2-methylsulfanyl-quinazoline MLS000326736 cid_1479841 4-(4-chlorophenyl)sulfanyl-2-methylsulfanylquinazoline 4-[(4-chlorophenyl)thio]-2-(methylthio)quinazoline SMR000179289 BDBM56495 4-chlorophenyl 2-(methylsulfanyl)-4-quinazolinyl sulfide
4-[5-(4-Fluoro-phenyl)-3-piperidin-4-yl-3H-imidazol-4-yl]-pyridine CHEMBL279416 4-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl)pyridine VK-19911 BDBM50099331
BDBM21416 4-Alkyl-4-methoxypiperidine derivative, 8h 4-{4-[(4-chlorophenyl)methyl]-4-methoxypiperidin-1-yl}-N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene)sulfonyl]benzamide
BDBM50128642 4-(4-Methoxy-benzenesulfonyl)-1-(4-thiophen-2-yl-benzyl)-piperidine-4-carboxylic acid hydroxyamide CHEMBL80183 1-(4-(thiophen-2-yl)benzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide
BDBM50308013 4-(4-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methyl)piperazin-1-yl)phenol 1-(4-Hydroxyphenyl)-4-{[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]methyl}piperazine CHEMBL597412
CHEMBL80798 4-(4-Methoxy-benzenesulfonyl)-1-(4-pyridin-2-yl-benzyl)-piperidine-4-carboxylic acid hydroxyamide BDBM50128641 1-(4-(pyridin-2-yl)benzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide
CHEMBL93687 4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-4-METHYL-TETRAHYDRO-PYRAN;COMPOUND WITH N-HYDROXY-ACETAMIDE BDBM50146636 2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE
N-[4-(4-pyridylmethyl)phenyl]acetamide N-[4-(pyridin-4-ylmethyl)phenyl]ethanamide N-(4-Pyridin-4-ylmethyl-phenyl)-acetamide cid_653424 N-[4-(pyridin-4-ylmethyl)phenyl]acetamide MLS000077309 BDBM62564 SMR000001037
1-(4-Fluorophenyl)-4-[4-([2.2]paracyclophan-4-yl)-4-hydroxypiperidin-1-yl]butan-1-one BDBM50328443 CHEMBL1257688
Aceperone N-{1-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-4-phenyl-piperidin-4-ylmethyl}-acetamide CHEMBL136298 BDBM50133938
BDBM249318 US9763943, 8-4 US10765676, Example 8-4 US9993479, 8-4 US10300060, Example 8-4 US9463192, 8-4
BDBM50019947 Propionic acid 1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-4-phenyl-piperidin-4-yl ester CHEMBL299471
BDBM50082680 4-(4-Chloro-phenyl)-1-(4-cyano-4-naphthalen-2-yl-butyl)-4-hydroxy-piperidinium; iodide CHEMBL342444
BDBM50098281 2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-(4-morpholin-4-yl-phenyl)-pent-4-ynoic acid CHEMBL10792
BDBM50166497 CHEMBL370034 1,2-Bis-(4-chloro-phenyl)-4-[4-(4-fluoro-phenyl)-4-oxo-butyl]-pyrazolidine-3,5-dione
BDBM50320410 CHEMBL1084208 N-hydroxy-4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide
BDBM50328445 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-1-([2.2]paracyclophan-4-yl)butan-1-one CHEMBL1257810
BDBM50343050 4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide CHEMBL1770698
BDBM50343078 CHEMBL1771213 N-hydroxy-4-(4-(4-(4-methoxybenzoyl)piperazin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide
CHEMBL1084510 BDBM50320414 1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenylsulfonyl)piperidine-4-carboxamide
SMR000377951 cid_4275980 4-(4-nitrophenyl)-4-imidazoline-2-thione 4-(4-nitrophenyl)-1,3-dihydroimidazole-2-thione BDBM50664 MLS001005047
US10765676, Example 15-4 US9763943, 15-4 US9463192, 15-4 US10300060, Example 15-4 US9993479, 15-4 BDBM249325
2-chloro-4-hydroxybenzoic acid (4-propylphenyl) ester (4-propylphenyl) 2-chloranyl-4-oxidanyl-benzoate 2-chloro-4-hydroxy-benzoic acid (4-propylphenyl) ester SMR000312304 MLS000681620 (4-propylphenyl) 2-chloro-4-hydroxybenzoate 4-propylphenyl 2-chloro-4-hydroxybenzoate BDBM76546 cid_3943124
4-(3-methylsulfanylanilino)-4-oxobutanoic acid 4-[(3-methylsulfanylphenyl)amino]-4-oxidanylidene-butanoic acid 4-keto-4-[3-(methylthio)anilino]butyric acid 4-[3-(methylsulfanyl)anilino]-4-oxobutanoic acid cid_696812 SMR000230645 MLS000704966 4-[3-(methylthio)anilino]-4-oxobutanoic acid BDBM55652
4-({[(4-biphenylylcarbonyl)amino]carbonothioyl}amino)benzoic acid 4-[(4-phenylphenyl)carbonylcarbamothioylamino]benzoic acid 4-[[[[oxo-(4-phenylphenyl)methyl]amino]-sulfanylidenemethyl]amino]benzoic acid 4-[(4-phenylbenzoyl)thiocarbamoylamino]benzoic acid BDBM65283 4-[(4-phenylbenzoyl)carbamothioylamino]benzoic acid SMR000298980 cid_1017047 MLS000676426
5-(4-chlorobenzylidene)-2-thioxothiazolidin-4-one BDBM50181730 (Z)-5-(4'-Chlorobenzylidene)-2-thioxothiazolidin-4-one 5-(4-chlorobenzylidene)-4-oxo-2-thionothiazolidine (Z)-5-(4-chlorobenzyliden)-2-thioxothiazolidin-4-one (Z)-5-(4-Chlorobenzylidene)-2-thioxothiazolidin-4-one CHEMBL201467
MLS001078021 N'-[4-(4-ethoxyphenyl)-4-oxobutanoyl]-2-hydroxybenzohydrazide SMR000709694 N'-[4-(4-ethoxyphenyl)-1,4-dioxobutyl]-2-hydroxybenzohydrazide BDBM96394 N'-[4-(4-ethoxyphenyl)-4-oxidanylidene-butanoyl]-2-oxidanyl-benzohydrazide 2-hydroxy-N'-(4-keto-4-p-phenetyl-butanoyl)benzohydrazide cid_24979372
MLS001162260 (4-methyl-3-morpholin-4-ylsulfonylphenyl)-morpholin-4-ylmethanone SMR000670931 (4-methyl-3-morpholinosulfonyl-phenyl)-morpholino-methanone [4-methyl-3-(4-morpholinylsulfonyl)phenyl]-(4-morpholinyl)methanone BDBM58743 (4-methyl-3-morpholin-4-ylsulfonyl-phenyl)-morpholin-4-yl-methanone cid_6464135
N-(4-hydroxy-1-naphthyl)-4-methoxy-benzenesulfonamide SMR000069785 cid_871185 4-methoxy-N-(4-oxidanylnaphthalen-1-yl)benzenesulfonamide N-(4-hydroxy-1-naphthalenyl)-4-methoxybenzenesulfonamide N-(4-hydroxy-1-naphthyl)-4-methoxybenzenesulfonamide BDBM34412 MLS000061019 N-(4-hydroxynaphthalen-1-yl)-4-methoxybenzenesulfonamide
SMR000125020 4-(4-bromo-3-chloro-anilino)-4-keto-butyric acid N-(4-Bromo-3-chloro-phenyl)-succinamic acid BDBM89815 4-(4-bromo-3-chloroanilino)-4-oxobutanoic acid cid_722034 MLS000067650 4-[(4-bromanyl-3-chloranyl-phenyl)amino]-4-oxidanylidene-butanoic acid
cid_755971 (4-ethoxybenzyl)-(4-pyrrolidinophenyl)amine N-[(4-ethoxyphenyl)methyl]-4-pyrrolidin-1-yl-aniline MLS000062337 (4-ethoxybenzyl)[4-(1-pyrrolidinyl)phenyl]amine N-[(4-ethoxyphenyl)methyl]-4-pyrrolidin-1-ylaniline BDBM34625 N-[(4-ethoxyphenyl)methyl]-4-(1-pyrrolidinyl)aniline SMR000072932
BDBM41499 cid_1386650 4-[4-[6-bromanyl-4-(2-chlorophenyl)quinazolin-2-yl]piperazin-1-yl]-4-oxidanylidene-butanoic acid MLS000551396 4-[4-[6-bromo-4-(2-chlorophenyl)-2-quinazolinyl]-1-piperazinyl]-4-oxobutanoic acid 4-[4-[6-bromo-4-(2-chlorophenyl)quinazolin-2-yl]piperazino]-4-keto-butyric acid SMR000145321 4-[4-[6-bromo-4-(2-chlorophenyl)quinazolin-2-yl]piperazin-1-yl]-4-oxobutanoic acid 4-{4-[6-Bromo-4-(2-chloro-phenyl)-quinazolin-2-yl]-piperazin-1-yl}-4-oxo-butyric acid
SMR000664857 cid_2269266 MLS001083042 4-[(E)-[3-[4-(4-hydroxyanilino)-4-keto-butyl]-4-keto-2-thioxo-thiazolidin-5-ylidene]methyl]benzoic acid methyl ester methyl 4-[(E)-[3-[4-(4-hydroxyanilino)-4-oxobutyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]benzoate BDBM61770 methyl 4-[(E)-[3-[4-[(4-hydroxyphenyl)amino]-4-oxidanylidene-butyl]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]benzoate 4-[(E)-[3-[4-(4-hydroxyanilino)-4-oxobutyl]-4-oxo-2-sulfanylidene-5-thiazolidinylidene]methyl]benzoic acid methyl ester
BDBM45529 4-methylbenzoic acid (4-nitrosoanilino) ester benzo-1,4-quinone O-(4-methylbenzoyl)oxime oxime (4-nitrosoanilino) 4-methylbenzoate [(4-nitrosophenyl)amino] 4-methylbenzoate MLS000574149 cid_885280 SMR000195735
4-(4-CHLOROBENZYL)MORPHOLINE BDBM50487490
4-Methylester indole, 4 BDBM93043
BDBM110236 US9206232, 4 US8613914, 4
BDBM120089 US9259470, 4 US8697715, 4
BDBM144823 US8952157, 4 US9303025, 4
BDBM160063 US9040534, 4 US10047092, 4
BDBM168129 US9598426, 4 US9073936, 4
BDBM177581 US9120769, 4 US9663470, 4
BDBM179753 US9422318, 4 US9127027, 4
BDBM191610 US9278100, 4 US9181263, 4
BDBM198658 US9556143, 4 US9221791, 4
BDBM211688 US9670166, 4 US9290459, 4
BDBM235181 US9365558, 4 US9822074, 4
BDBM239165 4-Acetamidobenzoic acid (4)
BDBM254921 US9499542, 4 US9675594, 4
BDBM516433 US11053242, Compound 4-4
BDBM549011 WO2022098806, Compound 4-4
BDBM552517 WO2022098809, Example 4-4
BDBM82305 Terephthalaldehyde, 4-I-4
US10004738, 4 BDBM234451 US9353084, 4
US10016420, 4 BDBM209583 US9273011, 4
US20250066290, Example 4/4 BDBM724031
US8614234, 4 BDBM110536 US9725433, 4
US8940744, 4 US9266895, 4 BDBM143179
US9018381, 4 US9248140, 4 BDBM156380
US9034899, 4 BDBM159325 US9604960, 4
US9051321, 4 BDBM133660 US8846711, 4
US9067917, 4 US9682971, 4 BDBM164971
US9073869, 4 US8877775, 4 BDBM138494
US9115117, 4 BDBM175102 US9611251, 4
US9169243, 4 BDBM187356 US9908875, 4
US9303045, 4 US9695195, 4 BDBM221520
US9365529, 4 US8633196, 4 BDBM113576
US9475775, 4 BDBM254737 US9597333, 4
US9475809, 4 BDBM251892 US9918969, 4
US9526727, 4 BDBM150697 US8981112, 4
US9598436, 4 BDBM144615 US8969586, 4
US9630945, 4 US9409895, 4 BDBM241093
US9682959, 4 BDBM143697 US9751856, 4
US9688695, 4 US10047103, 4 BDBM175971
US9693992, 4 US9040714, 4 BDBM160337
1-(4-chlorophenyl)-4-(4-nitrophenyl)-4-imidazoline-2-thione 1-(4-chlorophenyl)-4-(4-nitrophenyl)-1,3-dihydro-2H-imidazole-2-thione cid_3578754 3-(4-chlorophenyl)-5-(4-nitrophenyl)-1H-imidazole-2-thione BDBM50297 MLS000583506 SMR000206692
4-[4-(2-bromo-6-chloro-4-methyl-phenoxy)butyl]morpholine 4-[4-(2-bromanyl-6-chloranyl-4-methyl-phenoxy)butyl]morpholine 4-[4-(2-bromo-6-chloro-4-methylphenoxy)butyl]morpholine cid_2299958 BDBM76327 SMR000271351 MLS000666761
4-amino-2-nitro-N-[4-(4-pyridylamino)phenyl]benzamide MLS003107169 4-azanyl-2-nitro-N-[4-(pyridin-4-ylamino)phenyl]benzamide BDBM94492 cid_4210858 4-amino-2-nitro-N-[4-(pyridin-4-ylamino)phenyl]benzamide SMR001822046
4-methyl-N-[4-(2-phenylthiazol-4-yl)phenyl]benzenesulfonamide BDBM113875 cid_2896660 MLS000697223 SMR000237709 4-methyl-N-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]benzenesulfonamide 4-methyl-N-[4-(2-phenyl-4-thiazolyl)phenyl]benzenesulfonamide
4-nitro-N-[4-(2-phenylthiazol-4-yl)phenyl]benzenesulfonamide 4-nitro-N-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]benzenesulfonamide MLS000573432 4-nitro-N-[4-(2-phenyl-4-thiazolyl)phenyl]benzenesulfonamide cid_2281861 BDBM57461 SMR000194934
L741,626 BDBM50050467 4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol L-741626 3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol CHEMBL445102
cid_4088367 SMR000237635 1-(4-chlorophenyl)sulfonyl-3,5-dimethyl-4-(4-nitrophenyl)sulfanyl-pyrazole MLS000697166 1-(4-chlorophenyl)sulfonyl-3,5-dimethyl-4-(4-nitrophenyl)sulfanylpyrazole 1-(4-chlorophenyl)sulfonyl-3,5-dimethyl-4-[(4-nitrophenyl)thio]pyrazole BDBM59445
BDBM63493 cid_16190545 ethyl 4-[(4-methoxyphenyl)methyl]-1-[(2-methyl-1,3-thiazol-4-yl)carbonyl]piperidine-4-carboxylate 1-(2-methylthiazole-4-carbonyl)-4-p-anisyl-isonipecotic acid ethyl ester ethyl 4-[(4-methoxyphenyl)methyl]-1-(2-methyl-1,3-thiazole-4-carbonyl)piperidine-4-carboxylate 4-[(4-methoxyphenyl)methyl]-1-[(2-methyl-4-thiazolyl)-oxomethyl]-4-piperidinecarboxylic acid ethyl ester MLS000734784 SMR000317807 ethyl 4-(4-methoxybenzyl)-1-[(2-methyl-1,3-thiazol-4-yl)carbonyl]piperidine-4-carboxylate
1-{4-[4-(4-amino-1-pyridiniumylmethyl)phenethyl]benzyl}-4-pyridiniumamine dibromide CHEMBL164858 BDBM50087653
1-{4-[4-(4-hydroxymethyl-1-pyridiniumylmethyl)phenethyl]benzyl}-4-pyridiniumylmethanol dibromide CHEMBL165437 BDBM50087661
4-(1H-imidazol-4-yl)phenol, 8 4-(1H-imidazol-4-yl)phenol BDBM24677
4-(4-(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoic acid BDBM50258132 CHEMBL492769
4-(4-(4-fluorophenyl)-2-(4-methylcyclohexyl)-1H-imidazol-5-yl)pyridine CHEMBL523938 BDBM50260229
4-Oxopyrimidine, 28e BDBM20543 4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)quinoline
4-Oxopyrimidine, 28f BDBM20544 4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)isoquinoline
4-[4-(4-Cyano-phenoxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide CHEMBL117375 BDBM50148220
4-[4-(4-Fluoro-benzyloxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide BDBM50148233 CHEMBL114528
4-[4-(4-Fluoro-phenylsulfanyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide CHEMBL112374 BDBM50148221
4-[4-(methylsulfanyl)phenyl]-1H-imidazole, 15 BDBM24673 4-[4-(methylsulfanyl)phenyl]-1H-imidazole
BDBM47957 (4-acetamidophenyl) 4-nitrobenzenesulfonate cid_1733550 4-nitrobenzenesulfonic acid (4-acetamidophenyl) ester MLS000712644 SMR000282411
BDBM50102481 4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanylmethyl-butyric acid CHEMBL83616
BDBM50148205 4-[4-(Pyridin-4-yloxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide CHEMBL114158
BDBM50148224 CHEMBL321257 4-[4-(4-Chloro-phenoxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
BDBM50156724 1-(4-bromobenzyl)-4-(4-pent-2-ynyloxybenzenesulfonyl)piperdine-4-carboxylicAcid hydroxyamide CHEMBL225331
BDBM50175857 4-((1H-imidazol-4-yl)methyl)-1-(4-(4-chlorophenyl)butyl)piperidine CHEMBL373010
BDBM50205766 1-(2-(4-chlorobenzyloxy)-5-bromobenzyl)-4-(4-bromophenyl)piperidin-4-ol CHEMBL234894
BDBM50209694 CHEMBL241375 1-(4'-fluoro-4-biphenylmethyl)-3-[1-(4-methylbenzyl)-4-piperidinyl]urea
BDBM50216050 3-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)quinazolin-4(3H)-one CHEMBL238718
BDBM50219061 N-(3-{1-[4-(4-chlorophenyl)-4-oxobutyl)-4-piperidinyl]phenyl}-acetamide CHEMBL243794
BDBM50219709 CHEMBL245994 N-(4-(4-fluorophenyl)thiazol-2-yl)-4-(pyrimidin-4-ylamino)benzamide
BDBM50253754 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-methyl-2,2-diphenylbutanamide CHEMBL1627
BDBM50257683 CHEMBL495345 1-(4-aminopyridin-2-yl)-N-(4-methoxybenzyl)-4-phenylpiperidine-4-carboxamide
BDBM50323643 4-(4-(4-(4-methylpiperazin-1-yl)phenylamino)quinolin-6-yl)benzaldehyde CHEMBL1209069
BDBM50334345 4-(3-(4-cyanophenyl)ureido)benzenesulfonamide 4-{[(4'-Cyanophenyl)carbamoyl]amino}benzenesulfonamide CHEMBL1643300
BDBM50334356 4-(3-(4-iodophenyl)ureido)benzenesulfonamide 4-{[(4'-Iodophenyl)carbamoyl]amino}benzenesulfonamide CHEMBL1643292
BDBM83879 SMR000075384 4-[(4-ethylbenzyl)amino]phenol MLS000063679 4-[(4-ethylphenyl)methylamino]phenol cid_833970
CHEMBL111856 BDBM50148216 4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
CHEMBL112470 4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetrahydro-thiopyran-4-carboxylic acid hydroxyamide BDBM50148210
CHEMBL113778 4-(4'-Fluoro-biphenyl-4-sulfonylamino)-tetrahydro-pyran-4-carboxylic acid hydroxyamide BDBM50148196
CHEMBL114906 BDBM50148212 4-[4-(4-Methoxy-phenoxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide
CHEMBL1643298 4-(3-(4-butoxyphenyl)ureido)benzenesulfonamide BDBM50334364 4-{[(4'-Butoxyphenyl)carbamoyl]amino}benzenesulfonamide
CHEMBL221717 1-(4-bromobenzyl)-4-(4-prop-2-ynyloxybenzenesulfonyl)piperdine-4-carboxylicAcid hydroxyamide BDBM50156714
CHEMBL241376 BDBM50209697 1-(4'-methoxy-4-biphenylmethyl)-3-[1-(4-methylbenzyl)-4-piperidinyl]urea
CHEMBL244163 BDBM50219056 N-(3-{1-[4-(4-chlorophenyl)-4-oxobutyl]-4-piperidinyl}phenyl)-cyclohexanecarboxamide
CHEMBL349401 1-{4-[4-(4-cyano-1-pyridiniumylmethyl)phenethyl]benzyl}-4-pyridiniumcarbonitrile dibromide BDBM50087654
CHEMBL398549 BDBM50219652 N-(4-(4-nitrophenyl)thiazol-2-yl)-4-(pyrimidin-4-ylamino)benzamide
MLS001180456 BDBM93869 4-(4-phenylphenyl)pyrimidine SMR000475731 4-[1,1'-biphenyl]-4-ylpyrimidine cid_817541
N-(3-{1-[4-(4-methylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl}-acetamide BDBM50219057 CHEMBL395789
N-(4-(4-chlorophenyl)thiazol-2-yl)-4-(pyridazin-4-ylamino)benzamide CHEMBL247014 BDBM50219676
N-(4-(4-chlorophenyl)thiazol-2-yl)-4-(pyrimidin-4-ylamino)benzamide CHEMBL399136 BDBM50219642
US10683309, Example 4 BDBM445666 Ex. 4/KM-06-78/(I-4) US11028104, Example 4
US9663506, Example 4-124 US9278960, 4-123 US9278960, 4-44 US9278960, 4-124 BDBM212960
cid_332219 MLS000714144 BDBM54924 4-[(4-phenylmethoxyphenyl)methylideneamino]phenol SMR000274124 4-[(4-benzoxybenzylidene)amino]phenol
cid_833988 MLS000063786 BDBM32115 4-[(4-methylphenyl)methylamino]phenol SMR000075600 4-[(4-methylbenzyl)amino]phenol
{4-[5-(4-chlorophenyl)-6-morpholin-4-ylpyrimidin-4-ylethynyl]phenyl}dimethylamine CHEMBL387630 BDBM50201830
(4-methoxyphenyl)-(4-quinolyl)amine;hydrochloride cid_6602913 MLS000047685 N-(4-methoxyphenyl)quinolin-4-amine;hydrochloride BDBM65855 SMR000033695 N-(4-methoxyphenyl)-4-quinolinamine;hydrochloride
(4-phenylphenyl)-(4-propylsulfonylpiperazin-1-yl)methanone MLS000110722 BDBM59395 (4-phenylphenyl)-(4-propylsulfonylpiperazino)methanone cid_1151712 (4-phenylphenyl)-(4-propylsulfonyl-1-piperazinyl)methanone SMR000106651
1-(4-Chloroanilino)-4-(4-pyridylmethyl)-5,6,7,8-tetrahydrophthalazine BDBM4868 CGP79787 Analog 53 N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-5,6,7,8-tetrahydrophthalazin-1-amine
1-(4-Chloroanilino)-4-(4-pyridylmethylamino)phthalazine BDBM4860 CGP79787 Analog 51 1-N-(4-chlorophenyl)-4-N-(pyridin-4-ylmethyl)phthalazine-1,4-diamine
1-Butyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide CHEMBL310324 BDBM50128653 1-butyl-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide
3-(4-fluorophenyl)-4-pyridin-4-ylquinoline-2(1H)-one CHEMBL434737 3-(4-fluorophenyl)-4-(pyridin-4-yl)quinolin-2(1H)-one BDBM50206422
4-(4-{4-[5-(4-Fluoro-phenyl)-3-piperidin-4-yl-3H-imidazol-4-yl]-pyrimidin-2-yloxy}-phenyl)-butyric acid BDBM50099356 CHEMBL13950
4-[4-methyl-6-(4-phenylphenoxy)-2-pyrimidinyl]morpholine cid_659795 4-[4-methyl-6-(4-phenylphenoxy)pyrimidin-2-yl]morpholine BDBM56914 MLS000079640 SMR000040743
4-ethoxy-N-pyridin-4-ylbenzamide MLS000107298 4-ethoxy-N-pyridin-4-yl-benzamide SMR000111669 4-ethoxy-N-(4-pyridyl)benzamide cid_803153 BDBM39311
4-phenyl-N-pyridin-4-yltetrahydro-2H-pyran-4-carboxamide BDBM25811 Compound 3455-1396 4-phenyl-N-(pyridin-4-yl)oxane-4-carboxamide
5-(4-methoxybenzylidene)-3-(4-hydroxyphenyl)-2-thioxothiazolidin-4-one CHEMBL376617 BDBM50211892 (Z)-5-(4-methoxybenzylidene)-3-(4-hydroxyphenyl)-2-thioxothiazolidin-4-one
8-(4-Methoxy-phenyl)-2-morpholin-4-yl-chromen-4-one BDBM50156501 8-(4-methoxyphenyl)-2-morpholin-4-yl-chromen-4-one CHEMBL363755
8-dibenzofuran-4-yl-2-morpholin-4-ylchromen-4-one BDBM50156503 CHEMBL186048 8-Dibenzofuran-4-yl-2-morpholin-4-yl-chromen-4-one
BDBM38729 MLS000106496 1-(4-butoxybenzyl)piperidin-4-ol 1-[(4-butoxyphenyl)methyl]piperidin-4-ol cid_2055522 1-[(4-butoxyphenyl)methyl]-4-piperidinol SMR000103463
BDBM46408 4-phenyl-N-pyridin-4-yl-benzamide MLS000717999 4-phenyl-N-(4-pyridyl)benzamide 4-phenyl-N-pyridin-4-ylbenzamide cid_765802 SMR000279567
BDBM50128652 1-benzyl-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide CHEMBL80969 1-Benzyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide
BDBM50128662 1-ethyl-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide CHEMBL310342 1-Ethyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide
BDBM94438 SMR000473286 cid_2054679 1-(4-butoxyphenyl)sulfonyl-4-methylpiperazine 1-(4-butoxyphenyl)sulfonyl-4-methyl-piperazine MLS001143847 1-[(4-butoxyphenyl)sulfonyl]-4-methylpiperazine
CHEMBL1082789 N-hydroxy-4-(4-(4-(4-(pyridin-4-yl)piperazine-1-carbonyl)piperidin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide BDBM50320440
CHEMBL81763 1-Cyclooctyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide BDBM50128634 1-cyclooctyl-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide
CHEMBL83218 4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenylamine 4-(4-(4-benzylpiperidin-1-yl)but-1-ynyl)aniline BDBM50078500
IM-094261 CHEMBL370586 4-(4-(4-tert-butylphenylamino)phthalazin-1-yl)benzamide BDBM50173019 4-[4-(4-tert-Butyl-phenylamino)-phthalazin-1-yl]-benzamide
MLS000037301 4-ethoxy-2-pyridin-4-yl-quinazoline 4-ethoxy-2-pyridin-4-ylquinazoline BDBM37885 cid_659823 4-ethoxy-2-(4-pyridyl)quinazoline SMR000035556
MLS000111678 [4-(hydroxyiminomethyl)phenyl] 4-methoxybenzoate 4-methoxybenzoic acid [4-(hydroxyiminomethyl)phenyl] ester BDBM62856 4-methoxybenzoic acid [4-(hydroximinomethyl)phenyl] ester SMR000107600 cid_880961
N-hydroxy-1-isopropyl-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide 1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide CHEMBL78709 BDBM50128675
SMR000103436 4-[(4-phenylpiperazin-1-yl)methyl]quinoline MLS000106469 4-[(4-phenylpiperazino)methyl]quinoline BDBM37266 4-[(4-phenyl-1-piperazinyl)methyl]quinoline cid_782193
SMR000120607 BDBM62922 MLS000528033 4-(4-pyrrol-1-ylphenyl)morpholine 4-[4-(1-pyrrolyl)phenyl]morpholine 4-(4-Pyrrol-1-yl-phenyl)-morpholine cid_882019
[4-[3-(4-aminophenoxy)phenoxy]phenyl]amine MLS000719868 4-[3-(4-azanylphenoxy)phenoxy]aniline cid_17201 SMR000304397 4-[3-(4-aminophenoxy)phenoxy]aniline BDBM54332
alpha-sulfone 27b N-hydroxy-4-[(4-phenoxybenzene)sulfonyl]piperidine-4-carboxamide BDBM11872 1-N-Hydroxy-4-[(4-phenoxyphenyl)sulfonyl]piperidine-4-carboxamide
cid_76075 [4-(4-phenylphenyl)thiazol-2-yl]amine 4-(4-phenylphenyl)-2-thiazolamine 4-(4-phenylphenyl)-1,3-thiazol-2-amine BDBM49948 SMR000354210 MLS001017970
cis-1-[4-(4-fluorophenoxy)cyclohexyl]-3-(4-trifluoromethoxyphenyl)urea 1-[4-(4-fluoro-phenoxy)-cyclohexyl]-3-(4-trifluoromethoxy-phenyl)-urea CHEMBL221014 BDBM50194498
methyl 4-(4-(4-carbamoylphenyl)phthalazin-1-ylamino)benzoate BDBM50173025 4-[4-(4-Carbamoyl-phenyl)-phthalazin-1-ylamino]-benzoic acid methyl ester CHEMBL196610
quinazolin-4(1H)-one 1H-quinazolin-4-one BDBM50339022 4-quinazolone CHEMBL266540 quinazolin-4(3H)-one 3H-Quinazolin-4-one quinazolin-4-ol
1-(4-fluorophenyl)-4-(1-piperidinylsulfonyl)piperazine cid_973778 MLS000064463 1-(4-fluorophenyl)-4-piperidin-1-ylsulfonylpiperazine SMR000078208 1-(4-fluorophenyl)-4-piperidinosulfonyl-piperazine BDBM62761 1-(4-fluorophenyl)-4-piperidin-1-ylsulfonyl-piperazine
1-(4-methoxyphenyl)-4-(1-piperidinyl)phthalazine 1-(4-methoxyphenyl)-4-piperidin-1-yl-phthalazine BDBM77272 cid_2885308 1-(4-methoxyphenyl)-4-piperidin-1-ylphthalazine 1-(4-methoxyphenyl)-4-piperidino-phthalazine MLS000533876 SMR000141313
4-(2-methoxyanilino)-4-oxobutanoic acid 4-[(2-methoxyphenyl)amino]-4-oxobutanoic acid 4-keto-4-(o-anisidino)butyric acid BDBM41116 MLS000060916 cid_693069 SMR000069144 4-[(2-methoxyphenyl)amino]-4-oxidanylidene-butanoic acid
4-[(4-methoxy-3-methylphenyl)methyl]thiomorpholine cid_763295 4-[(4-methoxy-3-methyl-phenyl)methyl]thiomorpholine BDBM89891 MLS000532381 SMR000137339 4-(4-methoxy-3-methylbenzyl)thiomorpholine 4-(4-methoxy-3-methyl-benzyl)thiomorpholine
4-pent-4-en-2-ynyl-4-(3-phenylprop-2-ynyl)morpholin-4-ium;bromide cid_12273833 4-(4-penten-2-ynyl)-4-(3-phenyl-2-propynyl)morpholin-4-ium SMR000226218 BDBM51821 MLS000705869
BDBM21422 N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene)sulfonyl]-4-{4-methoxy-4-[(4-phenylphenyl)methyl]piperidin-1-yl}benzamide 4-Alkyl-4-methoxypiperidine derivative, 8n
BDBM50132368 CHEMBL104682 6-(4-(4-methylnaphthalen-1-yl)phenyl)-2-morpholin-4-yl-4H-thiopyran-4-one 2-[4-(4-Methyl-naphthalen-1-yl)-phenyl]-6-morpholin-4-yl-thiopyran-4-one
BDBM50342717 CHEMBL294747 4'-acetyl-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)biphenyl-4-carboxamide 4'-Acetyl-biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
MLS000417123 cid_2063317 BDBM88740 1-(4-methylbenzyl)-3-(p-tolyl)pyrazole-4-carbaldehyde 3-(4-methylphenyl)-1-[(4-methylphenyl)methyl]pyrazole-4-carbaldehyde 3-(4-methylphenyl)-1-[(4-methylphenyl)methyl]-4-pyrazolecarboxaldehyde SMR000264355
N-[(4-chlorophenyl)methyl]-4-propan-2-yl-benzamide MLS000578603 BDBM48725 cid_897873 N-(4-chlorobenzyl)-4-isopropyl-benzamide N-[(4-chlorophenyl)methyl]-4-propan-2-ylbenzamide N-(4-chlorobenzyl)-4-isopropylbenzamide SMR000197788
SB220025 SB4 BDBM15239 4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidin-2-amine CHEMBL274064 4-[5-(4-fluorophenyl)-3-(4-piperidyl)imidazol-4-yl]pyrimidin-2-amine
SMR000333348 BDBM56701 4-(benzoxymethyl)-1-(4-chlorophenyl)triazole MLS000696233 4-[(benzyloxy)methyl]-1-(4-chlorophenyl)-1H-1,2,3-triazole cid_1475809 1-(4-chlorophenyl)-4-(phenylmethoxymethyl)triazole 1-(4-chlorophenyl)-4-(phenylmethoxymethyl)-1,2,3-triazole
US10351563, Example 4 US9902722, Example 4 (S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-aminopyridin-4-yl)benzonitrile BDBM311156 US10544120, Example 4 US10155760, Example 4 US10981910, Example 4 US10723734, Example 4
1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-4-(4-chloro-3-trifluoromethyl-phenyl)-piperidin-4-ol CHEMBL47050 Penfluridol PENFLURIDOL1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-4-(4-chloro-3-trifluoromethyl-phenyl)-piperidin-4-ol BDBM50026066 1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol
2-[[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]methyl]-1,3-thiazol-4-ol cid_1482058 2-[[4-(4-methoxyphenyl)thiazol-2-yl]methyl]thiazol-4-ol 2-{[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]methyl}-1,3-thiazol-4-ol SMR000338436 2-[[4-(4-methoxyphenyl)-2-thiazolyl]methyl]-4-thiazolol BDBM60254 MLS000736186
2-amino-6-(4-chlorophenyl)sulfanyl-4-(4-methoxyphenyl)pyridine-3,5-dicarbonitrile 2-azanyl-6-(4-chlorophenyl)sulfanyl-4-(4-methoxyphenyl)pyridine-3,5-dicarbonitrile BDBM66673 2-amino-6-[(4-chlorophenyl)thio]-4-(4-methoxyphenyl)pyridine-3,5-dicarbonitrile cid_2818996 MLS000859091 SMR000459270 2-amino-6-[(4-chlorophenyl)thio]-4-(4-methoxyphenyl)dinicotinonitrile
3-bromanyl-4-ethoxy-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide SMR000074453 3-bromo-4-ethoxy-N-[4-(4-methyl-1-piperazinyl)phenyl]benzamide cid_1017508 3-bromo-4-ethoxy-N-[4-(4-methylpiperazino)phenyl]benzamide 3-bromo-4-ethoxy-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide BDBM40639 MLS000049130
4-(4-chloranyl-2-methyl-phenoxy)-N-(4-methylpyridin-2-yl)butanamide 4-(4-chloro-2-methylphenoxy)-N-(4-methyl-2-pyridinyl)butanamide 4-(4-chloro-2-methyl-phenoxy)-N-(4-methyl-2-pyridyl)butyramide cid_3148040 MLS000717238 SMR000278605 4-(4-chloro-2-methylphenoxy)-N-(4-methylpyridin-2-yl)butanamide BDBM56697
4-(4-chlorophenyl)-N-[4-methyl-2-(4-methylpiperazino)-6-quinolyl]piperazine-1-carbothioamide BDBM78726 SMR000308805 4-(4-chlorophenyl)-N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]piperazine-1-carbothioamide cid_16189174 4-(4-chlorophenyl)-N-[4-methyl-2-(4-methyl-1-piperazinyl)-6-quinolinyl]-1-piperazinecarbothioamide MLS000730529
4-(4-fluorophenyl)-N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]piperazine-1-carbothioamide BDBM78772 cid_16193035 SMR000308795 4-(4-fluorophenyl)-N-[4-methyl-2-(4-methyl-1-piperazinyl)-6-quinolinyl]-1-piperazinecarbothioamide 4-(4-fluorophenyl)-N-[4-methyl-2-(4-methylpiperazino)-6-quinolyl]piperazine-1-carbothioamide MLS000730519
4-[4-(4-chlorophenyl)sulfonyl-2-(2-methylpropyl)-1,3-oxazol-5-yl]morpholine cid_654847 SMR000012142 4-[4-(4-chlorophenyl)sulfonyl-2-(2-methylpropyl)-5-oxazolyl]morpholine BDBM74448 4-[4-(4-Chloro-benzenesulfonyl)-2-isobutyl-oxazol-5-yl]-morpholine 4-[4-(4-chlorophenyl)sulfonyl-2-isobutyl-oxazol-5-yl]morpholine MLS000071591
4-keto-N-(2-methyl-4-nitro-phenyl)-4-piperidino-butyramide cid_6457175 SMR000670360 MLS001162542 N-(2-methyl-4-nitro-phenyl)-4-oxidanylidene-4-piperidin-1-yl-butanamide N-(2-methyl-4-nitrophenyl)-4-oxo-4-piperidin-1-ylbutanamide N-(2-methyl-4-nitrophenyl)-4-oxo-4-(1-piperidinyl)butanamide BDBM64302
4-methyl-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]-1,2,3-thiadiazole-5-carboxamide 4-methyl-N-[4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl]-5-thiadiazolecarboxamide MLS001116113 4-methyl-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]thiadiazole-5-carboxamide BDBM89407 SMR000625846 4-methyl-N-[4-(4-methylpiperidino)sulfonylphenyl]thiadiazole-5-carboxamide cid_16453294
BDBM44190 4-chloranyl-N-[1-(4-fluorophenyl)-3,5-dimethyl-pyrazol-4-yl]benzenesulfonamide SMR000067694 4-chloro-N-[1-(4-fluorophenyl)-3,5-dimethyl-4-pyrazolyl]benzenesulfonamide MLS000097470 cid_2093597 4-chloro-N-[1-(4-fluorophenyl)-3,5-dimethyl-pyrazol-4-yl]benzenesulfonamide 4-chloro-N-[1-(4-fluorophenyl)-3,5-dimethylpyrazol-4-yl]benzenesulfonamide
BDBM91101 4-tert-butyl-N-[4-(2,6-dimethylmorpholin-4-yl)carbonylphenyl]benzenesulfonamide SMR000673172 4-tert-butyl-N-[4-(2,6-dimethylmorpholine-4-carbonyl)phenyl]benzenesulfonamide MLS001146543 4-tert-butyl-N-{4-[(2,6-dimethyl-4-morpholinyl)carbonyl]phenyl}benzenesulfonamide cid_4404616 4-tert-butyl-N-[4-[(2,6-dimethyl-4-morpholinyl)-oxomethyl]phenyl]benzenesulfonamide
MLS000948477 N-(4-ethylphenyl)-5-[4-(methylthio)phenyl]-4-phenyl-1,3,4-thiadiazol-4-ium-2-amine;chloride cid_24789718 (4-ethylphenyl)-[5-[4-(methylthio)phenyl]-4-phenyl-1,3,4-thiadiazol-4-ium-2-yl]amine;chloride SMR000526893 N-(4-ethylphenyl)-5-(4-methylsulfanylphenyl)-4-phenyl-1,3,4-thiadiazol-4-ium-2-amine;chloride BDBM61134
MLS001206916 BDBM76652 4-(4-fluorophenyl)-N-(4-methyl-2-pyridinyl)-2-thiazolamine 4-(4-fluorophenyl)-N-(4-methylpyridin-2-yl)-1,3-thiazol-2-amine SMR000524298 cid_1092431 [4-(4-fluorophenyl)thiazol-2-yl]-(4-methyl-2-pyridyl)amine [4-(4-Fluoro-phenyl)-thiazol-2-yl]-(4-methyl-pyridin-2-yl)-amine
N-(2-chlorophenyl)-4-keto-4-[N'-[(4-sulfamoylphenyl)thiocarbamoyl]hydrazino]butyramide MLS001035637 N-(2-chlorophenyl)-4-oxo-4-[2-[(4-sulfamoylphenyl)carbamothioyl]hydrazinyl]butanamide BDBM53303 cid_2208299 SMR000666399 N-(2-chlorophenyl)-4-oxo-4-[[(4-sulfamoylanilino)-sulfanylidenemethyl]hydrazo]butanamide N-(2-chlorophenyl)-4-oxidanylidene-4-[2-[(4-sulfamoylphenyl)carbamothioyl]hydrazinyl]butanamide
SMR000293079 cid_1017506 5-(4-bromophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamide MLS000662174 5-(4-bromophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furamide 5-(4-bromophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide BDBM83342 5-(4-bromophenyl)-N-[4-(4-methylpiperazino)phenyl]-2-furamide
SMR000688565 4-[4-(2-hydroxyethyl)piperazin-1-yl]-N-(4-methoxyphenyl)-3-nitro-benzenesulfonamide BDBM89421 cid_24685438 MLS001149196 4-[4-(2-hydroxyethyl)-1-piperazinyl]-N-(4-methoxyphenyl)-3-nitrobenzenesulfonamide 4-[4-(2-hydroxyethyl)piperazin-1-yl]-N-(4-methoxyphenyl)-3-nitrobenzenesulfonamide 4-[4-(2-hydroxyethyl)piperazino]-N-(4-methoxyphenyl)-3-nitro-benzenesulfonamide
cid_24791840 SMR000671719 [4-[[1-(4-ethylbenzyl)-4-piperidyl]oxy]phenyl]-piperidino-methanone BDBM84315 MLS001122460 [4-[[1-[(4-ethylphenyl)methyl]-4-piperidinyl]oxy]phenyl]-(1-piperidinyl)methanone [4-[1-[(4-ethylphenyl)methyl]piperidin-4-yl]oxyphenyl]-piperidin-1-yl-methanone [4-[1-[(4-ethylphenyl)methyl]piperidin-4-yl]oxyphenyl]-piperidin-1-ylmethanone
cid_24817062 [4-[[1-[(4-fluorophenyl)methyl]-4-piperidinyl]oxy]phenyl]-(1-pyrrolidinyl)methanone MLS001083234 SMR000655325 [4-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]oxyphenyl]-pyrrolidin-1-yl-methanone [4-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]oxyphenyl]-pyrrolidin-1-ylmethanone BDBM84331 [4-[[1-(4-fluorobenzyl)-4-piperidyl]oxy]phenyl]-pyrrolidino-methanone
cid_2976095 2-[4-(2-methyl-4-quinolinyl)-1-piperazinyl]-4-phenylthiazole 2-[4-(2-methyl-4-quinolyl)piperazino]-4-phenyl-thiazole SMR000296383 2-[4-(2-methylquinolin-4-yl)piperazin-1-yl]-4-phenyl-1,3-thiazole 2-methyl-4-[4-(4-phenyl-1,3-thiazol-2-yl)-1-piperazinyl]quinoline BDBM94995 MLS000664665
2-[4-[(E)-[[4-[2-[(4-chlorophenyl)amino]-1,3-thiazol-4-yl]phenyl]carbonylhydrazinylidene]methyl]phenoxy]ethanoic acid 2-[4-[(E)-[[4-[2-(4-chloroanilino)-1,3-thiazol-4-yl]benzoyl]hydrazinylidene]methyl]phenoxy]acetic acid MLS-0312565.0001 2-[4-[(E)-[[4-[2-(4-chloroanilino)thiazol-4-yl]benzoyl]hydrazono]methyl]phenoxy]acetic acid 2-[4-[(E)-[[[4-[2-(4-chloroanilino)-4-thiazolyl]phenyl]-oxomethyl]hydrazinylidene]methyl]phenoxy]acetic acid BDBM46247 cid_9595032
3-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]-4-oxidanylidene-butyl]-2-sulfanylidene-1H-quinazolin-4-one AS-920-37a cid_24178258 3-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-[4-(2-hydroxyphenyl)piperazino]-4-keto-butyl]-2-thioxo-1H-quinazolin-4-one 3-[4-[4-(2-hydroxyphenyl)-1-piperazinyl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one BDBM42010 US20240208944, Compound 43
3-[4-[4-(3-hydroxyphenyl)piperazin-1-yl]-4-oxidanylidene-butyl]-2-sulfanylidene-1H-quinazolin-4-one AS-920-37b cid_24178259 3-[4-[4-(3-hydroxyphenyl)piperazino]-4-keto-butyl]-2-thioxo-1H-quinazolin-4-one BDBM42011 3-[4-[4-(3-hydroxyphenyl)piperazin-1-yl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-[4-(3-hydroxyphenyl)-1-piperazinyl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one
4-[2-(4-chloroanilino)thiazol-4-yl]-N'-[(4-ketocyclohexa-2,5-dien-1-ylidene)methyl]benzohydrazide 4-[2-(4-chloroanilino)-4-thiazolyl]-N'-[(4-oxo-1-cyclohexa-2,5-dienylidene)methyl]benzohydrazide 4-[2-[(4-chlorophenyl)amino]-1,3-thiazol-4-yl]-N'-[(4-oxidanylidenecyclohexa-2,5-dien-1-ylidene)methyl]benzohydrazide cid_5766948 MLS-0435412.0001 4-[2-(4-chloroanilino)-1,3-thiazol-4-yl]-N'-[(4-oxocyclohexa-2,5-dien-1-ylidene)methyl]benzohydrazide BDBM65962
4-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-4-oxobutanamide BDBM44611 SMR000045631 4-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-4-oxidanylidene-butanamide MLS000082900 cid_664649 4-[4-(4-chlorobenzyl)piperazino]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-4-keto-butyramide 4-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-4-oxobutanamide
5-(4-chlorobenzoyl)-6-(3-ethoxy-4-hydroxyphenyl)-4-hydroxy-4-(trifluoromethyl)-1,3-diazinan-2-one MLS000112191 5-(4-chlorobenzoyl)-6-(3-ethoxy-4-hydroxy-phenyl)-4-hydroxy-4-(trifluoromethyl)hexahydropyrimidin-2-one 5-(4-chlorophenyl)carbonyl-6-(3-ethoxy-4-oxidanyl-phenyl)-4-oxidanyl-4-(trifluoromethyl)-1,3-diazinan-2-one 5-[(4-chlorophenyl)-oxomethyl]-6-(3-ethoxy-4-hydroxyphenyl)-4-hydroxy-4-(trifluoromethyl)-1,3-diazinan-2-one cid_2911939 BDBM33619 SMR000108107
BDBM42008 3-[4-[4-(naphthalen-1-ylmethyl)piperazin-1-yl]-4-oxidanylidene-butyl]-2-sulfanylidene-1H-quinazolin-4-one cid_24178256 3-[4-[4-(naphthalen-1-ylmethyl)piperazin-1-yl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one AS-924-39a 3-[4-[4-(1-naphthalenylmethyl)-1-piperazinyl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-keto-4-[4-(1-naphthylmethyl)piperazino]butyl]-2-thioxo-1H-quinazolin-4-one
BDBM53574 4-[5-[[4-(4-fluorophenyl)-1-piperazinyl]sulfonyl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid 4-[5-[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]-4-oxidanylidene-butanoic acid SMR000097559 US8623906, XW2-011B 4-[5-[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]-4-oxobutanoic acid MLS000120717 US9174969, XW2-011B 4-[5-[4-(4-fluorophenyl)piperazino]sulfonylindolin-1-yl]-4-keto-butyric acid cid_5309616
BDBM54048 2-[4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxo-1-imidazolidinyl]-N-(4-sulfamoylphenyl)acetamide 2-[4-[4-(difluoromethoxy)phenyl]-2,5-diketo-4-methyl-imidazolidin-1-yl]-N-(4-sulfamoylphenyl)acetamide cid_4993844 2-[4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(4-sulfamoylphenyl)acetamide 2-[4-[4-[bis(fluoranyl)methoxy]phenyl]-4-methyl-2,5-bis(oxidanylidene)imidazolidin-1-yl]-N-(4-sulfamoylphenyl)ethanamide MLS001002164 SMR000368694
BDBM91232 cid_16302335 SMR001246930 3-[4-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]-4-oxobutyl]-1,3-diazaspiro[4.4]nonane-2,4-dione 3-[4-keto-4-[4-(4-methoxyphenyl)sulfonylpiperazino]butyl]-1,3-diazaspiro[4.4]nonane-2,4-quinone 3-[4-[4-(4-methoxyphenyl)sulfonyl-1-piperazinyl]-4-oxobutyl]-1,3-diazaspiro[4.4]nonane-2,4-dione 3-[4-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]-4-oxidanylidene-butyl]-1,3-diazaspiro[4.4]nonane-2,4-dione MLS002164559
N-[4-[methyl-[2-[4-(4-methyl-1-piperazinyl)anilino]-4-pyrimidinyl]amino]phenyl]-2-propenamide N-[4-[methyl-[2-[4-(4-methylpiperazino)anilino]pyrimidin-4-yl]amino]phenyl]acrylamide cid_42601357 SMR001307847 BDBM79297 N-[4-[methyl-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide MLS002232293 N-[4-[methyl-[2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
SMR000127633 3-[4-keto-4-[4-(4-methoxyphenyl)piperazino]butyl]-1H-thieno[3,2-d]pyrimidine-2,4-quinone cid_9550190 3-[4-[4-(4-methoxyphenyl)piperazin-1-yl]-4-oxobutyl]-1H-thieno[3,2-d]pyrimidine-2,4-dione BDBM48473 3-[4-[4-(4-methoxyphenyl)-1-piperazinyl]-4-oxobutyl]-1H-thieno[3,2-d]pyrimidine-2,4-dione 3-[4-[4-(4-methoxyphenyl)piperazin-1-yl]-4-oxidanylidene-butyl]-1H-thieno[3,2-d]pyrimidine-2,4-dione MLS000522366
cid_24178257 BDBM42009 3-[4-(4-naphthalen-1-ylpiperazin-1-yl)-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-[4-(1-naphthalenyl)-1-piperazinyl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one 3-[4-keto-4-[4-(1-naphthyl)piperazino]butyl]-2-thioxo-1H-quinazolin-4-one AS-924-39b 3-[4-(4-naphthalen-1-ylpiperazin-1-yl)-4-oxidanylidene-butyl]-2-sulfanylidene-1H-quinazolin-4-one
1-(4-methoxyphenyl)-4-[4-(phenylmethyl)-1-piperazinyl]pyrazolo[3,4-d]pyrimidine BDBM79564 1-(4-methoxyphenyl)-4-[4-(phenylmethyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine 4-(4-benzylpiperazino)-1-(4-methoxyphenyl)pyrazolo[3,4-d]pyrimidine cid_1388911 4-(4-benzyl-1-piperazinyl)-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine MLS000663497 4-(4-benzylpiperazin-1-yl)-1-(4-methoxyphenyl)pyrazolo[3,4-d]pyrimidine SMR000292653
1-[4-(4-bromo-3-methylphenyl)sulfonyl-1-piperazinyl]-4-(4-morpholinyl)butane-1,4-dione 1-[4-(4-bromo-3-methylphenyl)sulfonylpiperazin-1-yl]-4-morpholin-4-ylbutane-1,4-dione BDBM87507 1-[4-(4-bromo-3-methyl-phenyl)sulfonylpiperazino]-4-morpholino-butane-1,4-dione MLS002636716 1-[4-(4-bromanyl-3-methyl-phenyl)sulfonylpiperazin-1-yl]-4-morpholin-4-yl-butane-1,4-dione cid_2481264 SMR000365187
2-imino-3-[4-(4-methoxyphenyl)-2-thiazolyl]-4-thiazolidinone 2-imino-3-[4-(4-methoxyphenyl)thiazol-2-yl]thiazolidin-4-one 2'-Imino-4-(4-methoxy-phenyl)-[2,3']bithiazolyl-4'-one 2-azanylidene-3-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1,3-thiazolidin-4-one cid_1213087 MLS000566476 SMR000178033 2-imino-3-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1,3-thiazolidin-4-one BDBM60231
4-(4-acetamidoanilino)-4-keto-butyric acid [2-keto-2-(3-nitrophenyl)ethyl] ester [2-(3-nitrophenyl)-2-oxidanylidene-ethyl] 4-[(4-acetamidophenyl)amino]-4-oxidanylidene-butanoate BDBM67268 4-(4-acetamidoanilino)-4-oxobutanoic acid [2-(3-nitrophenyl)-2-oxoethyl] ester cid_2883150 SMR000268065 [2-(3-nitrophenyl)-2-oxoethyl] 4-(4-acetamidoanilino)-4-oxobutanoate MLS000684263 2-(3-nitrophenyl)-2-oxoethyl 4-{[4-(acetylamino)phenyl]amino}-4-oxobutanoate
4-(4-chlorophenyl)-6-(isopropylamino)-2-(4-pyridyl)pyrimidine-5-carbonitrile cid_1480476 4-(4-chlorophenyl)-6-(propan-2-ylamino)-2-pyridin-4-yl-5-pyrimidinecarbonitrile 4-(4-chlorophenyl)-6-(isopropylamino)-2-(4-pyridinyl)-5-pyrimidinecarbonitrile BDBM69274 MLS000694526 4-(4-chlorophenyl)-6-(propan-2-ylamino)-2-pyridin-4-yl-pyrimidine-5-carbonitrile 4-(4-chlorophenyl)-6-(propan-2-ylamino)-2-pyridin-4-ylpyrimidine-5-carbonitrile SMR000333194
4-(7-chloroquinolin-4-yl)-N-[4-(trifluoromethoxy)phenyl]tetrahydropyrazine-1(2H)-carboxamide MLS000830171 4-(7-chloro-4-quinolyl)-N-[4-(trifluoromethoxy)phenyl]piperazine-1-carboxamide cid_2809986 SMR000458092 4-(7-chloranylquinolin-4-yl)-N-[4-(trifluoromethyloxy)phenyl]piperazine-1-carboxamide BDBM58223 4-(7-chloro-4-quinolinyl)-N-[4-(trifluoromethoxy)phenyl]-1-piperazinecarboxamide 4-(7-chloroquinolin-4-yl)-N-[4-(trifluoromethoxy)phenyl]piperazine-1-carboxamide
BDBM40365 ethyl 4-[4-[[(4-methoxyphenyl)sulfonylamino]methyl]phenyl]carbonylpiperazine-1-carboxylate MLS000091950 SMR000026474 4-[4-[[(4-methoxyphenyl)sulfonylamino]methyl]benzoyl]piperazine-1-carboxylic acid ethyl ester cid_3241212 ethyl 4-[4-({[(4-methoxyphenyl)sulfonyl]amino}methyl)benzoyl]piperazine-1-carboxylate 4-[[4-[[(4-methoxyphenyl)sulfonylamino]methyl]phenyl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester ethyl 4-[4-[[(4-methoxyphenyl)sulfonylamino]methyl]benzoyl]piperazine-1-carboxylate
BDBM71439 cid_2177431 MLS001034902 (Z)-4-[3-[(4-methylphenyl)carbamoyl]-4-piperidin-1-ylanilino]-4-oxobut-2-enoic acid (Z)-4-keto-4-[4-piperidino-3-(p-tolylcarbamoyl)anilino]but-2-enoic acid (Z)-4-[3-[(4-methylanilino)-oxomethyl]-4-(1-piperidinyl)anilino]-4-oxo-2-butenoic acid (Z)-4-[[3-[(4-methylphenyl)carbamoyl]-4-piperidin-1-yl-phenyl]amino]-4-oxidanylidene-but-2-enoic acid SMR000665367
MLS000732761 N-(4-{[4-(hydroxymethyl)-4-(2-phenoxyethyl)piperidin-1-yl]methyl}phenyl)acetamide N-[4-[[4-(hydroxymethyl)-4-(2-phenoxyethyl)piperidin-1-yl]methyl]phenyl]acetamide cid_16189112 N-[4-[[4-methylol-4-(2-phenoxyethyl)piperidino]methyl]phenyl]acetamide BDBM63432 SMR000315817 N-[4-[[4-(hydroxymethyl)-4-(2-phenoxyethyl)-1-piperidinyl]methyl]phenyl]acetamide N-[4-[[4-(hydroxymethyl)-4-(2-phenoxyethyl)piperidin-1-yl]methyl]phenyl]ethanamide
MLS001030075 10-hydroxy-11-(4-methyl-4-morpholin-4-iumyl)undecanoic acid methyl ester;iodide cid_16682274 methyl 11-(4-methylmorpholin-4-ium-4-yl)-10-oxidanyl-undecanoate;iodide BDBM61313 SMR000427263 4-(2-Hydroxy-10-methoxycarbonyl-decyl)-4-methyl-morpholin-4-ium 10-hydroxy-11-(4-methylmorpholin-4-ium-4-yl)undecanoic acid methyl ester;iodide methyl 10-hydroxy-11-(4-methylmorpholin-4-ium-4-yl)undecanoate;iodide
N-[4-[4-(3-chlorophenyl)piperazin-1-yl]-4-oxobutyl]thiophene-2-sulfonamide BDBM41235 N-[4-[4-(3-chlorophenyl)-1-piperazinyl]-4-oxobutyl]-2-thiophenesulfonamide N-[4-[4-(3-chlorophenyl)piperazino]-4-keto-butyl]thiophene-2-sulfonamide MLS000086469 N-{4-[4-(3-chlorophenyl)piperazin-1-yl]-4-oxobutyl}thiophene-2-sulfonamide SMR000022364 cid_3237909 N-[4-[4-(3-chlorophenyl)piperazin-1-yl]-4-oxidanylidene-butyl]thiophene-2-sulfonamide
[1-[(4-methoxy-3-methylphenyl)methyl]-4-(2-phenoxyethyl)-4-piperidinyl]methanol [1-(4-methoxy-3-methylbenzyl)-4-(2-phenoxyethyl)piperidin-4-yl]methanol [1-[(4-methoxy-3-methylphenyl)methyl]-4-(2-phenoxyethyl)piperidin-4-yl]methanol [1-[(4-methoxy-3-methyl-phenyl)methyl]-4-(2-phenoxyethyl)piperidin-4-yl]methanol MLS000732500 BDBM90427 cid_16191151 SMR000315470 [1-(4-methoxy-3-methyl-benzyl)-4-(2-phenoxyethyl)-4-piperidyl]methanol
[4-(4-fluorophenyl)-1-piperazinyl]-[1-[6-(4-morpholinyl)-3-pyridazinyl]-4-piperidinyl]methanone 4-[6-(4-{[4-(4-fluorophenyl)piperazin-1-yl]carbonyl}piperidin-1-yl)pyridazin-3-yl]morpholine MLS000092514 SMR000028064 cid_3243752 [4-(4-fluorophenyl)piperazino]-[1-(6-morpholinopyridazin-3-yl)-4-piperidyl]methanone BDBM56101 [4-(4-fluorophenyl)piperazin-1-yl]-[1-(6-morpholin-4-ylpyridazin-3-yl)piperidin-4-yl]methanone
[4-[(3,5-dimethyl-4-isoxazolyl)methoxy]-3-methoxyphenyl]-[4-(4-methylphenyl)sulfonyl-1-piperazinyl]methanone [4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]-3-methoxyphenyl]-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]methanone [4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]-3-methoxy-phenyl]-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]methanone MLS000056221 SMR000068021 [4-[(3,5-dimethylisoxazol-4-yl)methoxy]-3-methoxy-phenyl]-(4-tosylpiperazino)methanone cid_2516748 BDBM36982
methyl 2-[4-[[4-(4-fluorophenyl)piperazine-1-carbothioyl]amino]phenyl]acetate cid_2197424 MLS000579860 BDBM33728 methyl [4-({[4-(4-fluorophenyl)-1-piperazinyl]carbonothioyl}amino)phenyl]acetate SMR000199099 2-[4-[[4-(4-fluorophenyl)piperazine-1-carbothioyl]amino]phenyl]acetic acid methyl ester methyl 2-[4-[[4-(4-fluorophenyl)piperazin-1-yl]carbothioylamino]phenyl]ethanoate 2-[4-[[[4-(4-fluorophenyl)-1-piperazinyl]-sulfanylidenemethyl]amino]phenyl]acetic acid methyl ester
1-(4-ethoxyphenyl)-2-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]ethanone MLS000047357 cid_3244501 1-(4-ethoxyphenyl)-2-[4-(4-methoxyphenyl)sulfonyl-1-piperazinyl]ethanone 1-(4-ethoxyphenyl)-2-{4-[(4-methoxyphenyl)sulfonyl]piperazin-1-yl}ethanone 2-[4-(4-methoxyphenyl)sulfonylpiperazino]-1-p-phenetyl-ethanone SMR000033368 BDBM59688
2,6-dimorpholin-4-yl-N-[(4-propan-2-ylphenyl)methylideneamino]pyrimidin-4-amine SMR000268729 MLS000680538 cid_2892598 BDBM83918 2,6-bis(4-morpholinyl)-N-[(4-propan-2-ylphenyl)methylideneamino]-4-pyrimidinamine (2,6-dimorpholinopyrimidin-4-yl)-[(4-isopropylbenzylidene)amino]amine 4-isopropylbenzaldehyde (2,6-di-4-morpholinyl-4-pyrimidinyl)hydrazone
4-chlorobenzoic acid [(Z)-[amino-(4-morpholinosulfonylphenyl)methylene]amino] ester BDBM89065 4-chlorobenzoic acid [(Z)-[amino-[4-(4-morpholinylsulfonyl)phenyl]methylidene]amino] ester MLS-0454734.0001 cid_9583536 [(Z)-[amino-(4-morpholin-4-ylsulfonylphenyl)methylidene]amino] 4-chlorobenzoate [(Z)-[azanyl-(4-morpholin-4-ylsulfonylphenyl)methylidene]amino] 4-chloranylbenzoate
N-[3-cyano-4-(4-methylphenyl)sulfanyl-phenyl]-4-fluoranyl-benzamide BRD-K43069600-001-01-1 N-[3-cyano-4-[(4-methylphenyl)thio]phenyl]-4-fluorobenzamide N-[3-cyano-4-(p-tolylthio)phenyl]-4-fluoro-benzamide N-[3-cyano-4-(4-methylphenyl)sulfanylphenyl]-4-fluorobenzamide BDBM65745 cid_2769158
cid_23723457 ethyl 1-[4-(acetylamino)benzyl]-4-(2-phenylethyl)piperidine-4-carboxylate SMR000495779 1-(4-acetamidobenzyl)-4-phenethyl-isonipecotic acid ethyl ester BDBM83396 ethyl 1-[(4-acetamidophenyl)methyl]-4-(2-phenylethyl)piperidine-4-carboxylate MLS001000244 1-[(4-acetamidophenyl)methyl]-4-(2-phenylethyl)-4-piperidinecarboxylic acid ethyl ester
1-(4-chlorophenyl)-N-[[4-(4-methyl-1-piperazinyl)phenyl]methyl]methanesulfonamide BDBM45744 1-(4-chlorophenyl)-N-[[4-(4-methylpiperazin-1-yl)phenyl]methyl]methanesulfonamide 1-(4-chlorophenyl)-N-[4-(4-methylpiperazino)benzyl]methanesulfonamide MLS000850880 SMR000456897 cid_2738598
3-[(4-chlorophenyl)sulfonyl-methyl-amino]-N-(4-fluorophenyl)-4-methoxy-benzenesulfonamide cid_2974727 BDBM61483 MLS000582054 3-[(4-chlorophenyl)sulfonyl-methylamino]-N-(4-fluorophenyl)-4-methoxybenzenesulfonamide 3-[[(4-chlorophenyl)sulfonyl](methyl)amino]-N-(4-fluorophenyl)-4-methoxybenzenesulfonamide SMR000201271
4-[4-(4-fluorophenyl)sulfonyl-2-phenyl-1,3-oxazol-5-yl]morpholine SMR000668749 4-[4-(4-fluorophenyl)sulfonyl-2-phenyl-5-oxazolyl]morpholine cid_2964741 BDBM58750 MLS001125129 4-[4-(4-fluorophenyl)sulfonyl-2-phenyl-oxazol-5-yl]morpholine
4-[4-[2-(2-thienyl)quinazolin-4-yl]piperazino]phenol 4-[4-(2-thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol SMR000365148 cid_2469096 BDBM50556 4-[4-(2-thiophen-2-yl-4-quinazolinyl)-1-piperazinyl]phenol MLS000774046
SMR000505001 MLS001207283 BDBM94073 N-[4-[4-[4-(diethanoylamino)phenoxy]phenoxy]phenyl]-N-ethanoyl-ethanamide cid_1089417 N-acetyl-N-[4-[4-[4-(diacetylamino)phenoxy]phenoxy]phenyl]acetamide N-Acetyl-N-{4-[4-(4-diacetylamino-phenoxy)-phenoxy]-phenyl}-acetamide
cid_9268266 US11634404, Compound 65 [4-[2-(4-methoxyphenoxy)ethyl]piperazino]-(4-methoxyphenyl)methanone MLS001173843 SMR000596364 [4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone BDBM73920 [4-[2-(4-methoxyphenoxy)ethyl]-1-piperazinyl]-(4-methoxyphenyl)methanone
(4-{4-[4-(Chloro-difluoro-methoxy)-phenylamino]-phthalazin-1-yl}-phenyl)-morpholin-4-yl-methanone (4-(4-(4-(chlorodifluoromethoxy)phenylamino)phthalazin-1-yl)phenyl)(morpholino)methanone CHEMBL382710 BDBM50173020
4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)vinyl)piperidin-1-yl)-1-(phenylsulfonyl)piperidine CHEMBL72494 BDBM50092974 1'-Benzenesulfonyl-4-{1-[4-(4-methoxy-benzenesulfonyl)-phenyl]-vinyl}-[1,4']bipiperidinyl
BDBM45428 cid_691987 SMR000102946 [4-(dimethylamino)phenyl]-morpholino-methanethione [4-(dimethylamino)phenyl]-(4-morpholinyl)methanethione [4-(dimethylamino)phenyl]-morpholin-4-yl-methanethione MLS000105972 [4-(dimethylamino)phenyl]-morpholin-4-ylmethanethione
BDBM50092966 4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}-1'-phenylmethanesulfonyl-[1,4']bipiperidinyl 1-(benzylsulfonyl)-4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)vinyl)piperidin-1-yl)piperidine CHEMBL422770
CHEMBL73245 BDBM50092970 1'-Ethanesulfonyl-4-{1-[4-(4-methoxy-benzenesulfonyl)-phenyl]-vinyl}-[1,4']bipiperidinyl 1-(ethylsulfonyl)-4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)vinyl)piperidin-1-yl)piperidine
SMR000117119 2-(4-fluorophenyl)chromone 2-(4-Fluoro-phenyl)-chromen-4-one 2-(4-fluorophenyl)chromen-4-one 2-(4-fluorophenyl)-1-benzopyran-4-one BDBM89825 MLS000526645 cid_261391
US9713612, 4 US10285988, Compound 4 BDBM263575 N-(4-(2-methylpyridin-4-yl)benzyl)-2-(2-methylpyridin-4-yl)-1,6-naphthyridin-5-amine (Compound No. 4) US10087181, Compound 4
1-dimorpholin-4-ylphosphoryl-N'-(4-methoxyphenyl)-N-(4-nitroanilino)methanimidamide MLS000532778 SMR000140216 1-dimorpholinophosphoryl-N'-(4-methoxyphenyl)-N-(4-nitroanilino)formamidine 1-[bis(4-morpholinyl)phosphoryl]-N'-(4-methoxyphenyl)-N-(4-nitroanilino)methanimidamide cid_3769822 N-(4-methoxyphenyl)-1,1-di-4-morpholinyl-N'-(4-nitrophenyl)phosphinecarbohydrazonamide oxide 1-dimorpholin-4-ylphosphoryl-N'-(4-methoxyphenyl)-N-[(4-nitrophenyl)amino]methanimidamide BDBM44881
2-(N-(4-methoxyphenyl)sulfonylanilino)-N-[4-(4-morpholinylsulfonyl)phenyl]acetamide 2-(N-(4-methoxyphenyl)sulfonylanilino)-N-(4-morpholinosulfonylphenyl)acetamide 2-[(4-methoxyphenyl)sulfonyl-phenyl-amino]-N-(4-morpholin-4-ylsulfonylphenyl)ethanamide N~2~-[(4-methoxyphenyl)sulfonyl]-N~1~-[4-(4-morpholinylsulfonyl)phenyl]-N~2~-phenylglycinamide SMR000200126 2-(N-(4-methoxyphenyl)sulfonylanilino)-N-(4-morpholin-4-ylsulfonylphenyl)acetamide BDBM54802 cid_2958242 MLS000581499
5-(4-methylphenyl)-N-[4-(4-morpholinyl)phenyl]-4-thieno[2,3-d]pyrimidinamine;hydrochloride BDBM78156 (4-morpholinophenyl)-[5-(p-tolyl)thieno[2,3-d]pyrimidin-4-yl]amine;hydrochloride 5-(4-methylphenyl)-N-[4-(4-morpholinyl)phenyl]thieno[2,3-d]pyrimidin-4-amine hydrochloride MLS000575890 SMR000196922 5-(4-methylphenyl)-N-(4-morpholin-4-ylphenyl)thieno[2,3-d]pyrimidin-4-amine;hydrochloride cid_2921859
6-methyl-4-[4-(4-morpholinyl)anilino]-3-quinolinecarboxylic acid ethyl ester 6-methyl-4-(4-morpholinoanilino)quinoline-3-carboxylic acid ethyl ester ethyl 6-methyl-4-[(4-morpholin-4-ylphenyl)amino]quinoline-3-carboxylate cid_1190554 ethyl 6-methyl-4-{[4-(4-morpholinyl)phenyl]amino}-3-quinolinecarboxylate ethyl 6-methyl-4-(4-morpholin-4-ylanilino)quinoline-3-carboxylate MLS000575705 BDBM41085 SMR000196739
BDBM43754 4-(2-p-phenetylquinoline-4-carbonyl)piperazine-1-carboxylic acid ethyl ester SMR000031817 MLS000046206 ethyl 4-{[2-(4-ethoxyphenyl)quinolin-4-yl]carbonyl}piperazine-1-carboxylate cid_3237815 ethyl 4-[2-(4-ethoxyphenyl)quinoline-4-carbonyl]piperazine-1-carboxylate 4-[[2-(4-ethoxyphenyl)-4-quinolinyl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester ethyl 4-[2-(4-ethoxyphenyl)quinolin-4-yl]carbonylpiperazine-1-carboxylate
MLS000678706 2-hydroxy-6-(4-methoxyphenyl)-3-[(4-methoxyphenyl)-oxomethyl]-4-pyranone 6-(4-methoxyphenyl)-3-(4-methoxyphenyl)carbonyl-2-oxidanyl-pyran-4-one BDBM43271 cid_2905318 2-hydroxy-3-(4-methoxybenzoyl)-6-(4-methoxyphenyl)pyran-4-one 4-hydroxy-3-(4-methoxybenzoyl)-6-(4-methoxyphenyl)-2H-pyran-2-one 2-hydroxy-6-(4-methoxyphenyl)-3-p-anisoyl-pyran-4-one SMR000269767
N-[(3-bromo-4-ethoxy-5-methoxyphenyl)methyl]-4-(4-morpholinyl)aniline cid_979593 N-[(3-bromanyl-4-ethoxy-5-methoxy-phenyl)methyl]-4-morpholin-4-yl-aniline N-[(3-bromo-4-ethoxy-5-methoxyphenyl)methyl]-4-morpholin-4-ylaniline BDBM59002 SMR000295746 MLS000684106 (3-bromo-4-ethoxy-5-methoxy-benzyl)-(4-morpholinophenyl)amine (3-bromo-4-ethoxy-5-methoxybenzyl)[4-(4-morpholinyl)phenyl]amine
SMR000415899 MLS000779206 cid_4888929 N-[2-(4-Fluoro-phenyl)-4-oxo-1,4-dihydro-2H-quinazolin-3-yl]-succinamic acid BDBM100081 4-[[2-(4-fluorophenyl)-4-oxo-1,2-dihydroquinazolin-3-yl]amino]-4-oxobutanoic acid 4-[[2-(4-fluorophenyl)-4-oxidanylidene-1,2-dihydroquinazolin-3-yl]amino]-4-oxidanylidene-butanoic acid 4-[[2-(4-fluorophenyl)-4-keto-1,2-dihydroquinazolin-3-yl]amino]-4-keto-butyric acid
SMR000461476 1-(4-fluorophenyl)-N'-[(4-methylphenyl)-oxomethyl]-4-oxo-3-pyridazinecarbohydrazide cid_2745062 BDBM78917 N'3-(4-methylbenzoyl)-1-(4-fluorophenyl)-4-oxo-1,4-dihydropyridazine-3-carbohydrazide 1-(4-fluorophenyl)-N'-(4-methylphenyl)carbonyl-4-oxidanylidene-pyridazine-3-carbohydrazide 1-(4-fluorophenyl)-N'-(4-methylbenzoyl)-4-oxopyridazine-3-carbohydrazide MLS000833957 1-(4-fluorophenyl)-4-keto-N'-p-toluoyl-pyridazine-3-carbohydrazide
SMR000498875 2-[4-(2,6-dimethyl-4-morpholinyl)-4-oxobutyl]-1H-isoindole-1,3(2H)-dione BDBM69637 2-[4-(2,6-dimethylmorpholino)-4-keto-butyl]isoindoline-1,3-quinone MLS000999799 2-[4-(2,6-dimethyl-4-morpholinyl)-4-oxobutyl]isoindole-1,3-dione 2-[4-(2,6-dimethylmorpholin-4-yl)-4-oxidanylidene-butyl]isoindole-1,3-dione cid_18108378 2-[4-(2,6-dimethylmorpholin-4-yl)-4-oxobutyl]isoindole-1,3-dione
SMR001238730 4-(4-chloro-3-methylphenoxy)-N-(2-morpholin-4-yl-5-morpholin-4-ylsulfonylphenyl)butanamide 4-(4-chloranyl-3-methyl-phenoxy)-N-(2-morpholin-4-yl-5-morpholin-4-ylsulfonyl-phenyl)butanamide MLS002156223 cid_4857981 4-(4-chloro-3-methylphenoxy)-N-[2-(4-morpholinyl)-5-(4-morpholinylsulfonyl)phenyl]butanamide 4-(4-chloro-3-methyl-phenoxy)-N-(2-morpholino-5-morpholinosulfonyl-phenyl)butyramide BDBM91219
[4-azanyl-2-[(4-methoxyphenyl)amino]-1,3-thiazol-5-yl]-(4-fluorophenyl)methanone [4-amino-2-(p-anisidino)thiazol-5-yl]-(4-fluorophenyl)methanone [4-amino-2-(4-methoxyanilino)-1,3-thiazol-5-yl]-(4-fluorophenyl)methanone [4-amino-2-(4-methoxyanilino)-5-thiazolyl]-(4-fluorophenyl)methanone {4-amino-2-[(4-methoxyphenyl)amino]-1,3-thiazol-5-yl}(4-fluorophenyl)methanone cid_1512476 MLS001198207 SMR000559382 BDBM69798
[4-azanyl-2-[(4-methoxyphenyl)amino]-1,3-thiazol-5-yl]-(4-methoxyphenyl)methanone BDBM69812 {4-amino-2-[(4-methoxyphenyl)amino]-1,3-thiazol-5-yl}(4-methoxyphenyl)methanone [4-amino-2-(p-anisidino)thiazol-5-yl]-(4-methoxyphenyl)methanone MLS001198183 [4-amino-2-(4-methoxyanilino)-1,3-thiazol-5-yl]-(4-methoxyphenyl)methanone [4-amino-2-(4-methoxyanilino)-5-thiazolyl]-(4-methoxyphenyl)methanone cid_399618 SMR000559380
cid_2174062 [4-methoxy-3-[(4-methyl-1-piperidinyl)sulfonyl]phenyl]-(4-morpholinyl)methanone BDBM30933 [4-methoxy-3-(4-methylpiperidino)sulfonyl-phenyl]-morpholino-methanone MLS000062574 SMR000071584 [4-methoxy-3-(4-methylpiperidin-1-yl)sulfonylphenyl]-morpholin-4-ylmethanone 4-{4-methoxy-3-[(4-methyl-1-piperidinyl)sulfonyl]benzoyl}morpholine [4-methoxy-3-(4-methylpiperidin-1-yl)sulfonyl-phenyl]-morpholin-4-yl-methanone
cid_652867 N-[4-(dimethylamino)phenyl]-2-[4-[(4-methylphenyl)-oxomethyl]-1-piperidinyl]acetamide SMR000007079 MLS000074513 N-[4-(dimethylamino)phenyl]-2-[4-(4-methylbenzoyl)piperidin-1-yl]acetamide N-[4-(dimethylamino)phenyl]-2-(4-p-toluoylpiperidino)acetamide BDBM60347 N-[4-(dimethylamino)phenyl]-2-[4-(4-methylphenyl)carbonylpiperidin-1-yl]ethanamide N-(4-Dimethylamino-phenyl)-2-[4-(4-methyl-benzoyl)-piperidin-1-yl]-acetamide
(E)-1-(4-(4-bromophenyl)-4-oxobutan-2-ylidene)-4-(2-(7-chloroquinolin-4-ylamino)ethyl)thiosemicarbazide BDBM50225297 CHEMBL250155
1-[1-(4-Fluoro-phenyl)-piperidin-4-yl]-4-(4-methoxy-phenoxy)-4-phenyl-butan-1-one CHEMBL421787 BDBM50136184
1-[1-(4-Fluoro-phenyl)-piperidin-4-yl]-4-(4-nitro-phenoxy)-4-phenyl-butan-1-one CHEMBL153391 BDBM50136197
4-(3-(4-chlorophenyl)-5-(1-(pyridin-4-ylmethyl)piperidin-4-yl)-1H-pyrazol-4-yl)pyrimidine CHEMBL1093301 BDBM50315121
4-(4-((4'-(1-Cyanocyclopropyl)-4-fluoro-[1,1'-biphenyl]-2-yl)methoxy)phenyl)butanoic acid US10227360, Example 4 BDBM369410
4-(4-Amino-phenoxy)-1-[1-(4-fluoro-phenyl)-piperidin-4-yl]-4-phenyl-butan-1-one BDBM50136180 CHEMBL423034
4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-oxazol-2-yl]-1-methyl-piperidin-4-ol CHEMBL280149 BDBM50089129
5-({4-[(1R,5S)-8- US11197867, Example 4 BDBM329921 US10463675, Example 4 US10980815, Ex. No. 4 US9663526, Example 4
5-Fluoro-2-{4-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperazin-1-yl}-pyrimidin-4-ol BDBM50002324 CHEMBL140833
BDBM388455 N-(trans-4- morpholin-4- ylcyclohexyl)-6- (tetrahydro-2H- pyran-4- yl)quinazolin-4- amine US9943516, 3-4
BDBM50108134 CHEMBL306585 N-Hydroxy-N-{4-morpholin-4-yl-4-oxo-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-butyl}-formamide
BDBM50148701 CHEMBL326260 4-[5-(2-Cyclohexylamino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-oxazol-2-yl]-piperidin-4-ol
BDBM50148703 CHEMBL119699 4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-phenyl)-thiazol-2-yl]-piperidin-4-ol
BDBM50225296 (E)-1-(4-(4-bromophenyl)-4-oxobutan-2-ylidene)-4-(3-(7-chloroquinolin-4-ylamino)propyl)thiosemicarbazide CHEMBL399032
BDBM50320399 CHEMBL1085988 4-(4-(4-(4'-fluorobiphenyl-2-yl)piperidin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide
BDBM50320412 CHEMBL1084238 N-hydroxy-4-(4-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide
BDBM50320427 CHEMBL1082657 4-(4-(4-(4-acetylpiperazine-1-carbonyl)piperidin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide
BDBM50343064 CHEMBL1770710 N-hydroxy-4-(4-(4-oxo-4-(piperidin-1-yl)butoxy)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide
CHEMBL1083931 1-cyclopropyl-N-hydroxy-4-(4-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)phenylsulfonyl)piperidine-4-carboxamide BDBM50320390
CHEMBL121405 BDBM50148690 4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-phenyl)-oxazol-2-yl]-piperidin-4-ol
CHEMBL22978 4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-oxazol-2-yl]-1-methyl-piperidin-4-ol BDBM50089126
CHEMBL280524 4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-thiazol-2-yl]-1-methyl-piperidin-4-ol BDBM50089128
US11261191, Example 4 US9944645, 4 6-(4-Fluorophenyl)-3-(4-methoxybenzyl)imidazo[1,2-a]pyrimidine US10738052, Example 4 BDBM388650
succinamide peptidomimetic, 4 BDBM19638 (2R)-2-(cyclohexylmethyl)-N-{2-[(4-fluorophenyl)amino]ethyl}-4-(morpholin-4-yl)-4-oxobutanamide
(1Z)-4-(4-fluorophenoxy)-3-nitro-benzaldoxime (1Z)-4-(4-fluorophenoxy)-3-nitrobenzaldehyde oxime 4-(4-fluorophenoxy)-3-nitrobenzenecarbaldehyde oxime BDBM90548 MLS000694759 SMR000333077 (NZ)-N-[[4-(4-fluorophenoxy)-3-nitrophenyl]methylidene]hydroxylamine (NZ)-N-[[4-(4-fluoranylphenoxy)-3-nitro-phenyl]methylidene]hydroxylamine cid_5524476
2-(4-Isobutoxy-phenyl)-N-methyl-succinamic acid BDBM41751 2-(4-isobutoxyphenyl)-4-keto-4-(methylamino)butyric acid 4-(methylamino)-2-[4-(2-methylpropoxy)phenyl]-4-oxobutanoic acid 4-(methylamino)-2-[4-(2-methylpropoxy)phenyl]-4-oxidanylidene-butanoic acid MLS000068652 cid_647848 SMR000008612
3-(4-Methoxy-phenyl)-2-thioxo-imidazolidin-4-one SMR000212433 cid_757480 BDBM55582 3-(4-methoxyphenyl)-2-thioxo-4-imidazolidinone MLS000588808 3-(4-methoxyphenyl)-2-sulfanylidene-imidazolidin-4-one 3-(4-methoxyphenyl)-2-sulfanylidene-4-imidazolidinone 3-(4-methoxyphenyl)-2-sulfanylideneimidazolidin-4-one
4-isopropoxy-N-(4-morpholinylcarbonothioyl)benzamide 4-isopropoxy-N-(morpholine-4-carbothioyl)benzamide BDBM43411 N-morpholin-4-ylcarbothioyl-4-propan-2-yloxy-benzamide N-(morpholine-4-carbothioyl)-4-propan-2-yloxybenzamide N-[4-morpholinyl(sulfanylidene)methyl]-4-propan-2-yloxybenzamide MLS000681096 cid_880334 SMR000269358
BDBM114724 SMR000140404 isonicotinaldehyde [2-(4-methylphenyl)-4-quinazolinyl]hydrazone MLS000532966 2-(4-methylphenyl)-N-[(E)-pyridin-4-ylmethylideneamino]quinazolin-4-amine cid_5339422 [2-(p-tolyl)quinazolin-4-yl]-[(E)-4-pyridylmethyleneamino]amine 2-(4-methylphenyl)-N-[(E)-pyridin-4-ylmethylideneamino]-4-quinazolinamine
CHEMBL545608 US20240317745, Compound haloperidol 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl) 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one BDBM21398 Haloperidol CHEMBL54 Haloperidol, 1
MLS000591027 2-(4-chloranylphenoxy)-6-phenyl-pyrimidine-4-carbonitrile 2-(4-chlorophenoxy)-6-phenylpyrimidine-4-carbonitrile BDBM84246 2-(4-chlorophenoxy)-6-phenyl-pyrimidine-4-carbonitrile 2-(4-Chloro-phenoxy)-6-phenyl-pyrimidine-4-carbonitrile 2-(4-chlorophenoxy)-6-phenyl-4-pyrimidinecarbonitrile cid_929341 SMR000217860
MLS000769536 4-(4-methoxyphenoxy)-2-pyridin-2-yl-quinazoline BDBM58081 4-(4-methoxyphenoxy)-2-pyridin-2-ylquinazoline cid_929911 SMR000434264 4-(4-methoxyphenoxy)-2-(2-pyridyl)quinazoline 4-(4-methoxyphenoxy)-2-(2-pyridinyl)quinazoline 4-(4-Methoxy-phenoxy)-2-pyridin-2-yl-quinazoline
[4-(morpholine-4-carbothioyl)phenyl] 2-nitrobenzoate 2-nitrobenzoic acid [4-(morpholine-4-carbothioyl)phenyl] ester BDBM78357 (4-morpholin-4-ylcarbothioylphenyl) 2-nitrobenzoate MLS000974587 4-(4-morpholinylcarbonothioyl)phenyl 2-nitrobenzoate SMR000496801 2-nitrobenzoic acid [4-[4-morpholinyl(sulfanylidene)methyl]phenyl] ester cid_1352800
cid_800285 [4-(4-fluorobenzyl)oxyphenyl]-pyrrolidino-methanethione [4-[(4-fluorophenyl)methoxy]phenyl]-pyrrolidin-1-ylmethanethione MLS001163368 BDBM73835 1-({4-[(4-fluorobenzyl)oxy]phenyl}carbonothioyl)pyrrolidine [4-[(4-fluorophenyl)methoxy]phenyl]-pyrrolidin-1-yl-methanethione [4-[(4-fluorophenyl)methoxy]phenyl]-(1-pyrrolidinyl)methanethione SMR000497283
4-(4-fluorobenzyl)-5-({4-[(4-methylpiperidin-1-yl)carbonyl]piperidin-1-yl}carbonyl)-4H-thieno[3,2-b]pyrrole [1-[4-[(4-fluorophenyl)methyl]thieno[3,2-b]pyrrole-5-carbonyl]piperidin-4-yl]-(4-methylpiperidin-1-yl)methanone MLS000093518 SMR000029136 [1-[[4-[(4-fluorophenyl)methyl]-5-thieno[3,2-b]pyrrolyl]-oxomethyl]-4-piperidinyl]-(4-methyl-1-piperidinyl)methanone [1-[4-[(4-fluorophenyl)methyl]thieno[3,2-b]pyrrol-5-yl]carbonylpiperidin-4-yl]-(4-methylpiperidin-1-yl)methanone cid_3244084 [1-[4-(4-fluorobenzyl)thieno[3,2-b]pyrrole-5-carbonyl]-4-piperidyl]-(4-methylpiperidino)methanone BDBM41166
4-[4-(4-fluorophenyl)sulfonyl-1-piperazinyl]-4-oxo-N-(5-propyl-1,3,4-thiadiazol-2-yl)butanamide 4-[4-(4-fluorophenyl)sulfonylpiperazino]-4-keto-N-(5-propyl-1,3,4-thiadiazol-2-yl)butyramide 4-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]-4-oxo-N-(5-propyl-1,3,4-thiadiazol-2-yl)butanamide 4-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]-4-oxidanylidene-N-(5-propyl-1,3,4-thiadiazol-2-yl)butanamide MLS000778927 4-[4-(4-Fluoro-benzenesulfonyl)-piperazin-1-yl]-4-oxo-N-(5-propyl-[1,3,4]thiadiazol-2-yl)-butyramide BDBM63768 cid_3991922 SMR000415589
MLS000553886 (E)-4-oxidanylidene-4-[[4-[4-[[(E)-4-oxidanyl-4-oxidanylidene-but-2-enoyl]amino]phenoxy]phenyl]amino]but-2-enoic acid BDBM59933 3-{4-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenylcarbamoyl}-acrylic acid (E)-4-[4-[4-[[(E)-3-carboxy-1-oxoprop-2-enyl]amino]phenoxy]anilino]-4-oxo-2-butenoic acid (E)-4-[4-[4-[[(E)-3-carboxyacryloyl]amino]phenoxy]anilino]-4-keto-but-2-enoic acid (E)-4-[4-[4-[[(E)-3-carboxyprop-2-enoyl]amino]phenoxy]anilino]-4-oxobut-2-enoic acid cid_1083465 SMR000171556
MLS000699614 cid_9511214 SMR000229174 4-(4-bromophenyl)-3-[1-(4-chlorophenyl)-5-methyl-4-triazolyl]-1H-1,2,4-triazole-5-thione BDBM47772 4-(4-bromophenyl)-3-[1-(4-chlorophenyl)-5-methyl-1,2,3-triazol-4-yl]-1H-1,2,4-triazole-5-thione 4-(4-bromophenyl)-3-[1-(4-chlorophenyl)-5-methyl-triazol-4-yl]-1H-1,2,4-triazole-5-thione 4-(4-bromophenyl)-3-[1-(4-chlorophenyl)-5-methyltriazol-4-yl]-1H-1,2,4-triazole-5-thione 4-(4-bromophenyl)-5-[1-(4-chlorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-4H-1,2,4-triazole-3-thiol
NSC67436 Benzamide, 4-[(1-methyl-6-nitro-4(1H)-quinolinylidene)amino]-N-[4-[(1-methyl- 4(1H)-pyridinylidene)amino]phenyl]- 4-[(1-methyl-6-nitroquinolin-4-ylidene)amino]-N-[4-[(1-methylpyridin-4-ylidene)amino]phenyl]benzamide cid_319089 MLS000756593 SMR000528812 4-[(1-methyl-6-nitro-4-quinolinylidene)amino]-N-[4-[(1-methyl-4-pyridinylidene)amino]phenyl]benzamide 4-[(1-methyl-6-nitro-4-quinolylidene)amino]-N-[4-[(1-methyl-4-pyridylidene)amino]phenyl]benzamide 4-[(1-methyl-6-nitro-quinolin-4-ylidene)amino]-N-[4-[(1-methylpyridin-4-ylidene)amino]phenyl]benzamide BDBM53245
SMR000208894 3-({4-[(4-cyclohexylpiperazin-1-yl)carbonyl]benzyl}amino)-4-(4-methylpiperidin-1-yl)cyclobut-3-ene-1,2-dione 3-[[4-(4-cyclohexylpiperazine-1-carbonyl)phenyl]methylamino]-4-(4-methylpiperidin-1-yl)cyclobut-3-ene-1,2-dione 3-[[4-[(4-cyclohexyl-1-piperazinyl)-oxomethyl]phenyl]methylamino]-4-(4-methyl-1-piperidinyl)cyclobut-3-ene-1,2-dione 3-[[4-(4-cyclohexylpiperazin-1-yl)carbonylphenyl]methylamino]-4-(4-methylpiperidin-1-yl)cyclobut-3-ene-1,2-dione MLS000586964 cid_15944872 3-[[4-(4-cyclohexylpiperazine-1-carbonyl)benzyl]amino]-4-(4-methylpiperidino)cyclobut-3-ene-1,2-quinone BDBM78678
2-(4-methoxyphenyl)-N-(2-morpholino-5-morpholinosulfonyl-phenyl)cinchoninamide SMR000371715 BDBM61093 2-(4-methoxyphenyl)-N-(2-morpholin-4-yl-5-morpholin-4-ylsulfonyl-phenyl)quinoline-4-carboxamide 2-(4-methoxyphenyl)-N-[2-(4-morpholinyl)-5-(4-morpholinylsulfonyl)phenyl]-4-quinolinecarboxamide MLS000774435 cid_3676567 2-(4-methoxyphenyl)-N-(2-morpholin-4-yl-5-morpholin-4-ylsulfonylphenyl)quinoline-4-carboxamide
N-(4-chlorophenyl)-1-dimorpholin-4-ylphosphoryl-1-morpholin-4-ylmethanimine N-(4-chlorophenyl)-1-dimorpholin-4-ylphosphoryl-1-morpholin-4-yl-methanimine (4-chlorophenyl)-[dimorpholinophosphoryl(morpholino)methylene]amine 1-[bis(4-morpholinyl)phosphoryl]-N-(4-chlorophenyl)-1-(4-morpholinyl)methanimine cid_1215296 BDBM56340 MLS000547601 SMR000113968 N-(4-chlorophenyl)-N-[[di(4-morpholinyl)phosphoryl](4-morpholinyl)methylene]amine
SMR000237746 [4-[(4-methylphenyl)sulfonyl-pyridin-4-ylcarbonyl-amino]naphthalen-1-yl] pyridine-4-carboxylate 4-pyridinecarboxylic acid [4-[(4-methylphenyl)sulfonyl-[oxo(pyridin-4-yl)methyl]amino]-1-naphthalenyl] ester BDBM70808 isonicotinic acid [4-[isonicotinoyl(tosyl)amino]-1-naphthyl] ester [4-[(4-methylphenyl)sulfonyl-(pyridine-4-carbonyl)amino]naphthalen-1-yl] pyridine-4-carboxylate cid_3469947 MLS000696987
(4-methylpiperazin-1-yl)-(4-methylsulfanylphenyl)methanethione MLS000050644 (4-methyl-1-piperazinyl)-[4-(methylthio)phenyl]methanethione 1-methyl-4-{[4-(methylthio)phenyl]carbonothioyl}piperazine cid_1301808 SMR000078090 BDBM34476 (4-methylpiperazino)-[4-(methylthio)phenyl]methanethione
(4-methylpiperidino)-(2-p-phenetyl-4-quinolyl)methanone SMR000659109 BDBM96031 [2-(4-ethoxyphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone cid_1220197 [2-(4-ethoxyphenyl)-4-quinolinyl]-(4-methyl-1-piperidinyl)methanone MLS001125680
(Z)-5-(4'-Methoxybenzylidene)-2-thioxothiazolidin-4-one CHEMBL224521 (Z)-5-(4-methoxlbenzyliden)-2-thioxothiazolidin-4-one (Z)-5-(4-Methoxybenzylidene)-2-thioxothiazolidin-4-one 5-(4-methoxybenzylidene)-2-thioxothiazolidin-4-one BDBM50241157
3-(4-hydroxyphenyl)carbonyloxypropyl 4-oxidanylbenzoate 4-hydroxybenzoic acid 3-[(4-hydroxyphenyl)-oxomethoxy]propyl ester BDBM70085 cid_7503590 SMR000687939 4-hydroxybenzoic acid 3-(4-hydroxybenzoyl)oxypropyl ester 3-(4-hydroxybenzoyl)oxypropyl 4-hydroxybenzoate MLS001129781
4-(4-methoxyphenoxy)-N-pyridin-3-ylbutanamide SMR000154470 BDBM89917 4-(4-methoxyphenoxy)-N-(3-pyridinyl)butanamide MLS000568166 cid_4879650 4-(4-methoxyphenoxy)-N-(3-pyridyl)butyramide 4-(4-methoxyphenoxy)-N-pyridin-3-yl-butanamide
4-(4-nitrophenyl)-2-propan-2-yl-1,3-thiazole BDBM93801 MLS000681530 4-(4-nitrophenyl)-2-propan-2-ylthiazole cid_882371 SMR000269196 2-isopropyl-4-(4-nitrophenyl)-1,3-thiazole 2-isopropyl-4-(4-nitrophenyl)thiazole
4-[[(4-fluorophenyl)carbonylhydrazinylidene]methyl]benzoic acid cid_2403682 4-[[[(4-fluorophenyl)-oxomethyl]hydrazinylidene]methyl]benzoic acid MLS000339639 4-[[(4-fluorobenzoyl)hydrazinylidene]methyl]benzoic acid 4-[[(4-fluorobenzoyl)hydrazono]methyl]benzoic acid BDBM33785 SMR000242056
BDBM50153007 N-(4-(N-(4-(4-(dimethylamino)phenyl)-6-(4-methoxyphenyl)pyrimidin-2-yl)sulfamoyl)phenyl)acetamide N-{4-[4-(4-Dimethylamino-phenyl)-6-(4-methoxy-phenyl)-pyrimidin-2-ylsulfamoyl]-phenyl}-acetamide CHEMBL189764
N'-(4-chlorobenzoyl)-4-(dimethylamino)benzohydrazide cid_2803312 N'-(4-chlorophenyl)carbonyl-4-(dimethylamino)benzohydrazide SMR000457477 BDBM90755 MLS000833756 N'-[(4-chlorophenyl)-oxomethyl]-4-(dimethylamino)benzohydrazide N'1-(4-chlorobenzoyl)-4-(dimethylamino)benzene-1-carbohydrazide
SB242235 BDBM15458 4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]-2-methoxypyrimidine 4-[4-(4-fluorophenyl)-1-piperidin-4-yl-1H-imidazol-5-yl]-2-methoxypyrimidine CHEMBL95692 SB-242235
cid_1488716 SMR000178942 BDBM52361 2-(4-chloranylphenoxy)-4-(dimethylamino)pyridine-3-carbonitrile 2-(4-chlorophenoxy)-4-(dimethylamino)pyridine-3-carbonitrile MLS000326357 2-(4-chlorophenoxy)-4-(dimethylamino)nicotinonitrile 2-(4-chlorophenoxy)-4-(dimethylamino)-3-pyridinecarbonitrile
cid_7503584 3-(4-acetamidophenyl)carbonyloxypropyl 4-acetamidobenzoate SMR000687937 4-acetamidobenzoic acid 3-[(4-acetamidophenyl)-oxomethoxy]propyl ester MLS001149327 4-acetamidobenzoic acid 3-(4-acetamidobenzoyl)oxypropyl ester BDBM70126 3-(4-acetamidobenzoyl)oxypropyl 4-acetamidobenzoate
1-(4-tert-butylphenylsulfonyl)-4-methoxy-4-methylazepane BDBM50297219 CHEMBL561274
1-benzhydryl-4-(4-butylphenyl)piperidin-4-ol BDBM50210218 CHEMBL233287
4-((3',4'-Difluorobiphenyl-4-yl)methyl)pyridine BDBM50324617 CHEMBL1214660
4-(2-(4-hydroxyphenylamino)thiazol-4-yl)benzonitrile CHEMBL1081627 BDBM50312880
4-(4'-hydroxy-phenylamino)-4-oxo propanoic acid CHEMBL1275862 BDBM50330386
4-(4-(4-chlorophenyl)butyl)benzene-1,2-diol CHEMBL392589 BDBM50212960
4-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzonitrile CHEMBL1165632 BDBM50321162
4-(4-(4-methoxyphenyl)thiazol-2-ylamino)phenol CHEMBL1081480 BDBM50312881
4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-1,2-selenazole BDBM50245466 CHEMBL471501
4-(4-chlorophenylthio)-2-(pyridin-4-yl)pyrimidine CHEMBL206032 BDBM50182807
4-(5-(4-Hydroxyphenyl)isothiazol-4-yl)phenol BDBM50247852 CHEMBL491090
4-[1-(4'-Methoxybiphenyl-4-yl)propyl]pyridine BDBM50324608 CHEMBL1215596
BDBM111081 US9682910, 4-(4'-Hydroxybiphenyl)benzene-1,3-diol (4)
BDBM264717 US9718780, 4 (R)-2,3-dihydroxy-1-(6-(4-(4-
BDBM343406 US10442803, Example 4 US11091484, Example 4 US9777003, Example 4
BDBM356234 US10604535, Example 4 US9896458, No. 4 US9815850, Compound 4
BDBM388458 US9943516, 4-1 US9943516, 4-2 US9943516, 4-3
BDBM458530 US11466007, Example 4 US10745401, Example 4 US12180213, Example 4
BDBM50008200 4-(4-Chloro-benzoylamino)-4-pentylcarbamoyl-butyric acid CHEMBL127604
BDBM50180899 {4-[4-(4-bromophenoxy)benzoyl]phenyl}acetic acid CHEMBL201138
BDBM50210204 4-(1-benzhydryl-4-hydroxypiperidin-4-yl)benzonitrile CHEMBL233501
BDBM50212962 CHEMBL245547 4-(4-(4-methoxyphenyl)butyl)benzene-1,2-diol
BDBM50247683 4-(4-(4-phenoxyphenylamino)phthalazin-1-yl)benzamide CHEMBL455410
BDBM50293572 4-(4-(4-Hydroxyphenyl)thiazol-2-ylamino)benzenesulfonamide CHEMBL549321
BDBM50297212 1-(4-tert-butylphenylsulfonyl)-4-phenylazepan-4-ol CHEMBL554940
BDBM50297221 CHEMBL564215 1-(4-tert-butylphenylsulfonyl)-4-cyclopropyl-4-methoxyazepane
BDBM50297222 CHEMBL562644 1-(4-tert-butylphenylsulfonyl)-4-methoxy-4-phenylazepane
BDBM50304557 4-(4-Chlorophenylamino)-2-cinnamamido-4-oxobutanoic acid CHEMBL593793
BDBM50321135 CHEMBL1164371 4-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzenesulfonamide
BDBM50323622 4-(6-(4-chlorophenyl)quinolin-4-ylamino)benzonitrile CHEMBL1208823
BDBM50427345 US10654855, Example 4 CHEMBL2325983 US11236095, Example 4 US9492453, 4
BDBM780299 4-[[2-(4-fluoro-2-methyl- US12441703, Compound 4
CHEMBL1076549 4-(4-(4-chlorophenyl)thiazol-2-ylamino)benzamide BDBM50312872
CHEMBL1209834 4-(6-(4-chlorophenyl)quinolin-4-ylamino)phenol BDBM50323619
CHEMBL1243100 1-(4-fluorophenyl)-4-(4-(methylsulfonyl)phenyl)piperazine BDBM50326522
CHEMBL25093 BDBM50057467 4-[4-(4-Methyl-benzoyl)-benzoyl]-benzoic acid
CHEMBL263104 4-(4-(4-hydroxyphenyl)butyl)benzene-1,2-diol BDBM50212955
CHEMBL393675 1-benzhydryl-4-(4-propylphenyl)piperidin-4-ol BDBM50210210
CHEMBL471331 5-(4-Chlorophenyl)-4-(4-methoxyphenyl)-1,2-selenazole BDBM50245465
CHEMBL562674 BDBM50293585 4-(2-(4-Nitrophenylamino)thiazol-4-yl)phenol
CHEMBL564843 BDBM50297216 1-(4-tert-butylphenylsulfonyl)-4-methylazepan-4-ol
CHEMBL565094 BDBM50297217 1-(4-tert-butylphenylsulfonyl)-4-cyclopropylazepan-4-ol
CHEMBL596098 2-Cinnamamido-4-(4-nitrophenylamino)-4-oxobutanoic acid BDBM50304553
CHEMBL602084 BDBM50307070 4-Nitrophenyl 4-(4-Methoxybenzyl)piperazine-1-carboxylate
Ethyl 4-(4-iodophenyl)-piperidine-4-carboxylate hydrochloride BDBM50331518 CHEMBL1288490
Ex. Cpd. 4 US11046696, Compound 4 US10807986, Example 4 BDBM311539
US10226449, cpd 4 US20250017938, Compound 002-4 BDBM244395 US9428502, 4
US10329273, Example 4 BDBM38181 US10093650, Example 4 US11479538, Example 4
US10513522, Example 4 BDBM314691 US9611269, Example 4 US11214573, Example 4
US10584132, Compound 4 US10934305, Compound 4 BDBM285658 US10077273, Compound 4
US10723742, Example 4 US11510915, Example 4 US12435128, Example 4 BDBM456285
US10934296, Example 4 US9758524, Example 4 BDBM340081 US10239883, Example 4
US10947243, Example 4 US8969568, Example 4 BDBM144453 US9914735, Example 4
US10995088, Example 4 US10807974, Example 4 BDBM468986 US11608330, Example 4
US11013718, Compound 4 BDBM424914 US11547695, Compound 4 US10517849, Compound 4
US11046702, Example 4 US10100057, Example 4 US9745310, Example 4 BDBM292149
US11117902, Example 4 US10654866, Example 4 BDBM443450 US11634426, Example 4
US11401259, Example 4 US10774065, Example 4 US10093646, Example 4 BDBM38025
US11591316, Compound 4 BDBM436212 US10590114, No. 4 US11111235, No. 4
US11713315, Example 4 US10836763, Example 4 US10844057, Example 4 BDBM472918
US20250134869, Example 4 BDBM316516 US11111242, Example 4 US9617258, Example 4