Target (1)
Compound (988)
Article Title (2)
Assay (9)
SNC-80 CAS_123924 BDBM86513 NSC_123924
US9487511, 121 US9920047, 121 US9718814, 121 BDBM256726 US10414761, Example 121 US10968213, Example 121 US10053456, 121
US9475819, 121 BDBM163990 US9637496, 121 US9062078, 121 US9695183, 121
US10085990, Example 121 US10568888, Example 121 US9833457, 121 US9393245, 121 BDBM135822 US8853226, 121
US9089569, 121 US9695149, 121 US8952177, 121 BDBM145767
US10913746, Compound 121 US9777010, Compound 121 US11649240, Compound 121 US10407433, Compound 121 US10072016, Compound 121 US9434727, 121 BDBM249523
BDBM202774 US10245267, Example 121 US9242969, 121 US9694016, 121 US10709712, Example 121
US8940720, 121 US11136327, Example 121 US10487086, Example 121 US9802939, 121 BDBM142866
BDBM127748 US9782415, Example 121 US10251889, Example 121 US8791123, 121 US9796724, Example 121 US10758542, Example 121
US11667644, Example 121 USRE48841, Example 121 US9586962, Example 121 US8653263, 121 BDBM118468 US11059828, Example 121
US9688629, 121 US10604504, Example 121 US11623921, Example 121 BDBM165325 US9920031, Example 121 US9802915, Example 121
BDBM363633 US11021515, Compound 121 US10640534, Compound 121 US9850277, Compound 121 US10717764, Compound 121 US11667673, Compound 121 US10689414, Compound 121
BDBM150447 US10238633, Example 121 US9713606, 121 US8987249, 121
US10077266, Example 121 US9708313, 121 BDBM191008 US9181249, 121
US10640503, Example 121 US9695168, 121 US10047086, 121 BDBM105686
BDBM161336 US10087143, Compound 121 US10738009, Compound 121 US9051270, 121 US11673864, Compound 121
US10213433, Compound 121 US9174982, 121 BDBM189559 US20240043404, Example 121 US11369599, Compound 121
US10703749, Example 121 US10112937, Example 121 US9464084, 121 US10150765, Example 121 BDBM254236
US8846601, 121 US10632171, Peptide No. 121 US9458201, 121 BDBM135736 US10179804, Example 121
US9434697, 121 US10537571, Compound 121 BDBM249404 US10912774, Compound 121 US9730931, Compound 121
US20230271960, Compound 121 US20230293519, Compound 121 US11560376, Compound 121 US10793564, Compound 121 US11419869, Compound 121 BDBM465331
BDBM397058 US11591338, Example 121 US10844069, Example 121 US10442810, Example 121 US9981975, Example 121
BDBM513760 US11220509, Example 121 US11091495, Example 121 US20240398811, Example 121 US11485738, Example 121
US10287267, Compound 121 US10508099, Compound 121 US11673881, Compound 121 US11174244, Compound 121 BDBM385103
US10307413, Compound 121 US10980794, Cmpd No 121 US10391089, Compound 121 BDBM177004 US9675614, 121
US11535614, Compound 121 BDBM317968 US10807980, Compound 121 US9624217, Compound 121 US10399976, Compound 121
BDBM136890 US8865911, 121 US9918985, Example 121 US10231967, Example 121
BDBM172115 US11052093, Compound 121 US10155002, Compound 121 US9090562, 121
BDBM185302 US10011588, Example 121 US9156829, 121 US10689373, Example 121
BDBM241279 US11046688, Example 121 US10479788, Example 121 US9409907, 121
BDBM246216 US10183932, Example 121 US9434690, 121 US9822102, Example 121
US10544133, Example 121 US9657009, 121 BDBM283929 US10023562, Example 121
US9096596, 121 US10323032, Example 121 US9604982, Example 121 BDBM173408
US9321760, 121 US9662330, Compound 121 BDBM224444 US10080750, Compound 121
US9447106, 121 US10005782, Compound 121 BDBM249995 US9556188, Compound 121
US9452980, 121 US10501411, Example 121 US11697636, Example 121 BDBM250211
US9688672, Example 121 BDBM247561 US9434719, 121 US10112931, Example 121
BDBM110653 US8614234, 121 US9725433, 121
BDBM144939 US8952157, 121 US9303025, 121
BDBM165086 US9682971, 121 US9067917, 121
BDBM197521 US9216968, 121 US9732066, 121
BDBM70966 US9546164, 121 US9694002, 121
US10047103, 121 US9688695, 121 BDBM176088
US9040714, 121 US9693992, 121 BDBM160416
US9206232, 121 US8613914, 121 BDBM110353
US9663470, 121 US9120769, 121 BDBM177642
BDBM244512 US20250017938, Compound 002-121 US10226449, cpd 121 US9428502, 121
BDBM316631 US11111242, Example 121 US20250134869, Example 121 US9617258, Example 121
BDBM343522 US10442803, Example 121 US9777003, Example 121 US11091484, Example 121
BDBM365436 US10533001, Example 121 US11414410, Example 121 US9868729, Example 121
US10172864, Compound 121 US10028961, Compound 121 US10946023, Compound 121 BDBM279968
US10730877, Example 121 BDBM427688 US10544143, Example 121 US11053244, Example 121
US10800783, Example 121 US11396512, Example 121 US10233188, Example 121 BDBM370234
US10807986, Example 121 Ex. Cpd. 121 US11046696, Compound 121 BDBM311669
US10988451, Example 121 US10703733, Example 121 BDBM449508 US11643400, Example 121
US12180213, Example 121 BDBM458647 US10745401, Example 121 US11466007, Example 121
US9745310, Example 121 BDBM292266 US10100057, Example 121 US11046702, Example 121
BDBM136104 US8853203, 121 US9650377, Example 121
BDBM162502 US9611222, Example 121 US9056832, 121
BDBM171487 US9085576, 121 US9611261, Example 121
BDBM177891 US9120791, Example 121 US9603854, 121
BDBM215170 US9296736, 121 US9593129, Example 121
BDBM241489 US9409908, 121 US9951071, Example 121
BDBM244896 US9738649, Example 121 US9422293, 121
BDBM259880 US10308662, Compound 121 US9505780, 121
US10369153, Compound 121 US9346810, 121 BDBM228676
US9073922, 121 BDBM167635 US9796708, Example 121
US9200016, 121 US9902710, Compound 121 BDBM194439
US9216999, 121 US9556187, Example 121 BDBM198314
US9540323, 121 BDBM260930 US9540323, example 121
US9573943, Example 121 BDBM119392 US8669361, 121
US9604984, Example 121 US9346815, 121 BDBM232575
US9732093, Compound 121 BDBM167035 US9073876, 121
US9845313, Example 121 US9493448, 121 BDBM258215
BDBM50526723 US11608330, Example 121 CHEMBL4515085 US10807974, Example 121 US10995088, Example 121
US10618902, Compound I-121 US10189794, Compound I-121 US10774052, Compound I-121 BDBM94674 US9695132, I-121
US9987276, Compound I-121 US10828300, Compound I-121 BDBM397183 US10596172, Compound I-121 US11351168, Compound I-121
BDBM137053 US8871790, 121 US20250017938, Compound 001-121
BDBM271306 US10975091, Example 121 US10059720, Example 121
BDBM273342 US10478424, Example 121 US10071079, Example 121
BDBM348398 US9790229, Compound 121 US10577374, Compound 121
BDBM382409 US10273259, Example 121 US10711020, Example 121
BDBM414704 US10435405, Example 121 US10934288, Example 121
BDBM421531 US10995073, Example 121 US10508086, Example 121
BDBM434199 US10562891, Example 121 US11008308, Example 121
BDBM435005 US10584114, Compound 121 US11279688, Compound 121
BDBM448889 US10696672, Compound 121 US11634418, Compound 121
BDBM454953 US10730870, Example 121 US11512083, Example 121
BDBM459612 US10772893, Example 121 US11529356, Example 121
BDBM561581 US11390631, Example 121 US12268694, Example 121
BDBM578275 US11478474, Compound 121 US12070457, Compound 121
BDBM616615 US20230278996, Example 121. US12325701, Example 121.
CHEMBL1809155 US9771375, Example 121 BDBM50349728 US8822447, 121
US10072001, Example 121 BDBM276945 US10259811, Example 121
US10125118, Example 121 US10947215, Example 121 BDBM298715
US10166214, Example 121 US10675268, Example 121 BDBM311985
US10301317, Example 121 US9624228, Example 121 BDBM318165
US10485800, Example 121 US9814704, Example 121 BDBM354844
US10556902, No 121 BDBM430513 US11612599, Compound 121
US10562916, Compound 121 BDBM362561 US9834564, Compound 121
US10669246, Example 121 BDBM446064 US10968188, Example 121
US10723742, Example 121 BDBM456401 US11510915, Example 121
US10774053, Compound 121 US11352329, COMPD # 121 BDBM460999
US10774068, Example 121 BDBM461403 US11427560, Example 121
US10781211, Example 121 US10030020, Example 121 BDBM280576
US10807991, Compound 121 BDBM321310 US10179791, Compound 121
US10875852, Example 121 US10138229, Example 121 BDBM303609
US10934294, Example 121 BDBM484603 US11028092, Example 121
US11001575, Example 121 US10457669, Example 121 BDBM417507
US11014929, Example 121 BDBM499083 US11542265, Example 121
US11168090, Example 121 US11851434, Example 121 BDBM524677
US11236047, Example 121 US10544132, Example 121 BDBM427180
US11427601, Example 121 US10947252, Example 121 BDBM486681
US11453683, Example 121 BDBM573290 US20230279025, Example 121
US11459335, Compound 121 BDBM575324 US20230279023, Compound 121
US11530237, Compound 121 BDBM585950 US11542297, Compound 121
US11555029, No. 121 BDBM451981 US10710986, Example 121
US11911372, Example 121 US20240277683, Example 121 BDBM653698
US20250215014, Compound 121 BDBM756779 US20250223301, Compound 121
US8604016, 121 BDBM108558 US9938267, Cmpd ID 121
US9278960, 4-121 US9636337, 4-121 BDBM213037
US9598387, Compound 121 BDBM50057757 CHEMBL3323114 US9969743, 121
US9765068, Compound 121 US9745291, Compound 121 BDBM337075
BDBM423666 US11046698, Compound I-121 US10508120, Compound I-121 US10577373, Compound I-121
US10323036, Compound I-121 US10793574, Compound I-121 US11220508, Compound I-121 BDBM399677
US9932325, Example 106 US11111235, No. 121 US11591316, Compound 121 US10590114, No. 121 BDBM384420
US10017501, Compound 1020-121 BDBM249299 US9458145, 1020-121
US11040034, Ex. No. 121 BDBM287743 US10085984, Example 121
US9212153, 121,Ex. 86 BDBM195066 US10336717, Compound 121
US9682966, 121 US10118915, Compound 121 BDBM155896 US9682966, 120
US10392391, Compound I-N-121 US11117900, Compound I-N-121 US20230271963, Compound I-N-121 US11370798, Cmpd. # I-N-121 US10787452, Compound I-N-121 BDBM411689
US10562878, Compound trans 121 E1 US10562878, Compound trans 121 E2 BDBM433632 US10562878, Compound cis 121 E2 US10562878, Compound cis 121 E1
US10548896, Example 121 US10960005, Example 121 US9771329, Example 121 US10023543, Example 121 US11084793, Example 121 US10207999, Example 121 2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-phenyl)-1-methyl- 6-oxo-1,6-dihydro-pyrimidine-5- carbonitrile BDBM283231 US9573930, Example 121 US9776974, Example 121 US10023543, Example 19 US10328077, Example 19 US10849898, Example 121
BDBM337945 US9751854, Compound I-121 US9802960, Compound I-121
BDBM439813 US10633389, Example 121-1a US20230279020, Example 121-1a
BDBM442155 US11396508, Compound I-121 US10647713, Compound I-121
BDBM455100 US10730874, Compound I-121 US11352356, Compound I-121
BDBM565555 US12221453, Compound I-121 US11414431, Compound I-121
US10273223, Compound B-121 US9637472, Compound B-121 BDBM326033
US10533010, Example I-121 US11208415, Example I-121 BDBM429024
US10882866, Example Ib-121 US10717742, Example Ib-121 BDBM454413
US10961232, Compound I-121 US10479784, Compound I-121 BDBM420451
US11434240, Compound I-121 BDBM463642 US10781204, Compound I-121
US20230279020, Example 121-3 BDBM440456 US10633389, Example 121-3
US9732060, Compound I-121 US10065941, Compound I-121 BDBM271620
US9732060, Compound R-121 BDBM271806 US10065941, Compound R-121
US10723734, Example 121 BDBM311265 US9902722, Example 121 US10351563, Example 121 US10155760, Example 121 US10981910, Example 121 (S)-1-((4-(difluoromethyl)-6-(quinolin-4-yl)pyridin-3-yl)oxy)-2,4-dimethylpentan-2-amine US10544120, Example 121
BDBM101148 US8524917, 121
BDBM101624 US8530652, 121
BDBM103144 US8541407, 121
BDBM106505 US8586579, 121
BDBM106724 US8586620, 121
BDBM110701 US8614206, 121
BDBM111126 US9695179, 121
BDBM115794 US9682940, 121
BDBM118084 US8637558, 121
BDBM119564 US8680275, 121
BDBM121682 US8722692, 121
BDBM12257 US8846929, 121
BDBM125726 US8772305, 121
BDBM127046 US8785459, 121
BDBM128392 US8802721, 121
BDBM128951 US8802711, 121
BDBM130943 US8829190, 121
BDBM134119 US8846689, 121
BDBM134658 US8846698, 121
BDBM141220 US8653100, 121
BDBM142355 US8933099, 121
BDBM142528 US8933224, 121
BDBM143662 US9682955, 121
BDBM143920 US8969325, 121
BDBM144370 US8969358, 121
BDBM145342 US8952169, 121
BDBM146086 US8957068, 121
BDBM150316 US8987248, 121
BDBM150932 US8981106, 121
BDBM151686 US8987445, 121
BDBM151927 US8987457, 121
BDBM152040 US8987473, 121
BDBM152387 US8993565, 121
BDBM152924 US8993586, 121
BDBM153604 US8999975, 121
BDBM155691 US9012651, 121
BDBM157282 US9023865, 121
BDBM161213 US9051265, 121
BDBM161662 US9682976, 121
BDBM162226 US9682995, 121
BDBM163494 US9062048, 121
BDBM164310 US9688615, 121
BDBM164442 US9066954, 121
BDBM166057 US9067935, 121
BDBM169772 US9073940, 121
BDBM172882 US9096559, 121
BDBM178562 US9125913, 121
BDBM180236 US9133157, 121
BDBM181368 US9139568, 121
BDBM181918 US9145380, 121
BDBM182420 US9145392, 121
BDBM184252 US9150577, 121
BDBM185468 US9156845, 121
BDBM187537 US9169252, 121
BDBM188621 US9169246, 121
BDBM188855 US9169260, 121
BDBM191059 US9181253, 121
BDBM191126 US9181258, 121
BDBM191351 US9181272, 121
BDBM193202 US9193736, 121
BDBM194205 US9200001, 121
BDBM194940 US9206184, 121
BDBM195751 US9206173, 121
BDBM196016 US9206199, 121
BDBM197856 US9216988, 121
BDBM199057 US9221832, 121
BDBM201161 US9233953, 121
BDBM201357 US9187424, 121
BDBM201690 US9233979, 121
BDBM203564 US9221809, 121
BDBM203992 US9242996, 121
BDBM205652 US9255090, 121
BDBM206208 US9255110, 121
BDBM206383 US9260425, 121
BDBM208426 US9266835, 121
BDBM209821 US9273033, 121
BDBM210371 US9290451, 121
BDBM214060 US9283222, 121
BDBM214922 US9296734, 121
BDBM220532 US9296741, 121
BDBM220858 US9296759, 121
BDBM221006 US9302996, 121
BDBM221195 US9303012, 121
BDBM222830 US9315498, 121
BDBM223899 US9328112, 121
BDBM229055 US9556135, 121
BDBM229794 US9334269, 121
BDBM231096 US9340549, 121
BDBM231735 US9340517, 121
BDBM233514 US9351965, 121
BDBM241026 US9409892, 121
BDBM245666 US9428508, 121
BDBM248281 US9434711, 121
BDBM250488 US9464044, 121
BDBM250817 US9452986, 121
BDBM251439 US9452990, 121
BDBM252540 US9458172, 121
BDBM253161 US9458171, 121
BDBM255162 US9475817, 121
BDBM255370 US9481682, 121
BDBM255736 US9475815, 121
BDBM257103 US9493435, 121
BDBM257277 US9493440, 121
BDBM259608 US9505749, 121
BDBM260810 US9533989, 121
BDBM264399 US9714247, 121
BDBM265020 US9718792, 121
BDBM302209 US9598415, 121
BDBM302980 US9598440, 121
BDBM327581 US9663469, 121
BDBM47071 US8912224, 121
BDBM60516 US9085555, 121
BDBM60795 US9163021, 121
BDBM98309 US8481733, 121
BDBM99410 US8497281, 121
BDBM99620 US8501936, 121
US10047096, 121 BDBM227860
US8486940, 121 BDBM64741
US8501750, 121 BDBM99957
US8507533, 121 BDBM100814
US8530648, 121 BDBM102184
US8530648, 121 BDBM102250
US8552037, 121 BDBM103455
US8563553, 121 BDBM103696
US8569281, 121 BDBM105108
US8575145, 121 BDBM104214
US8575186, 121 BDBM104358
US8575201, 121 BDBM104630
US8586571, 121 BDBM106689
US8592431, 121 BDBM107343
US8592455, 121 BDBM106921
US8614223, 121 BDBM139335
US8623889, 121 BDBM112123
US8633206, 121 BDBM113203
US8637532, 121 BDBM116440
US8648092, 121 BDBM117190
US8669266, 121 BDBM119416
US8673938, 121 BDBM119224
US8674113, 121 BDBM118864
US8703768, 121 BDBM120521
US8729113, 121 BDBM122372
US8765744, 121 BDBM125200
US8772323, 121 BDBM180620
US8772480, 121 BDBM125303
US8778951, 121 BDBM126311
US8779142, 121 BDBM126098
US8791131, 121 BDBM127363
US8796244, 121 BDBM128542
US8796330, 121 BDBM128076
US8815926, 121 BDBM129842
US8829199, 121 BDBM130861
US8841312, 121 BDBM132375
US8841455, 121 BDBM132026
US8846658, 121 BDBM134404
US8846699, 121 BDBM133803
US8846719, 121 BDBM133435
US8846746, 121 BDBM132852
US8865726, 121 BDBM136490
US8871934, 121 BDBM137528
US8912181, 121 BDBM140495
US8912224, 121 BDBM140690
US8921389, 121 BDBM141664
US8957074, 121 BDBM147081
US8969341, 121 BDBM143493
US8969568, 121 BDBM144568
US8975260, 121 BDBM149474
US8975417, 121 BDBM150061
US9012443, 121 BDBM154473
US9018214, 121 BDBM156070
US9029370, 121 BDBM158327
US9034866, 121 BDBM158646
US9040528, 121 BDBM159979
US9056843, 121 BDBM162830
US9067871, 121 BDBM164643
US9067922, 121 BDBM165786
US9067949, 121 BDBM166264
US9073853, 121 BDBM166562
US9073870, 121 BDBM166825
US9073881, 121 BDBM167369
US9090564, 121 BDBM172307
US9096579, 121 BDBM173019
US9102637, 121 BDBM174086
US9120812, 121 BDBM178336
US9150526, 121 BDBM183868
US9150566, 121 BDBM184083
US9169224, 121 BDBM188432
US9199947, 121 BDBM193622
US9234000, 121 BDBM200130
US9242970, 121 BDBM202974
US9249163, 121 BDBM206907
US9260439, 121 BDBM207144
US9266876, 121 BDBM208654
US9266877, 121 BDBM209175
US9278981, 121 BDBM213529
US9290485, 121 BDBM212089
US9296745, 121 BDBM215565
US9302989, 121 BDBM215923
US9303023, 121 BDBM221424
US9321756, 121 BDBM224866
US9328106, 121 BDBM227173
US9328118, 121 BDBM225201
US9346786, 121 BDBM233317
US9346798, 121 BDBM231374
US9353090, 121 BDBM233993
US9353104, 121 BDBM234817
US9365562, 121 BDBM236083
US9394285, 121 BDBM238035
US9394309, 121 BDBM239664
US9394331, 121 BDBM240859
US9403813, 121 BDBM240215
US9409866, 121 BDBM240406
US9416129, 121 BDBM242343
US9428504, 121 BDBM245372
US9434725, 121 BDBM248890
US9447038, 121 BDBM249693
US9458110, 121 BDBM252050
US9458176, 121 BDBM252724
US9464076, 121 BDBM252973
US9468661, 121 BDBM254543
US9469631, 121 BDBM254720
US9481672, 121 BDBM255943
US9487483, 121 BDBM256269
US9493446, 121 BDBM257651
US9499482, 121 BDBM258722
US9505762, 121 BDBM259753
US9527851, 121 BDBM260511
US9675593, 121 BDBM168564
US9682965, 121 BDBM152686
US9682966, 121 BDBM155897
US9688680, 121 BDBM175570
US9693997, 121 BDBM70463
US9708359, 121 BDBM263159
US9718808, 121 BDBM266992
BDBM383838 US10550099, Compound I-121 US10280150, Cmpd No I-121
BDBM463444 US11091445, Compound code IA2-121 US10781182, Compound IA2-121
US11718603, Example 121 BDBM498295 US11014911, Example 121 US11014911, Example 120
US11718626, Compound T-121 US11053253, Cmp No. T-121 BDBM516711
US9150546, I-121 US9718790, I-0121 BDBM183077 US9688643, I-121
US9724435, Compound CM-121 CHEMBL271772 US9604926, Compound CM-121 BDBM50374597
US9999619, Example 122 US11285140, Example 121 US10695337, Example 121 BDBM400367
7-(1,1-dioxidothietan-3- US10189841, Compound I-121 US11161848, Compound I-121 BDBM324915 US10399980, Compound I-121
N-((6-amino-2-methylpyridin-3-yl)methyl)-2- ((6-fluoroquinolin-3-yl)methyl)isonicotinamide US9611252, Example 121 US11021463, Example 121 US10266515, Example 121 BDBM283469 US10023557, Example 121 US10308637, Example 121
BDBM50239489 US10793579, Example 122 CHEMBL4100091 US11702424, Example 121 US10329302, Example 121
US9527851, 48 US9527851, 121 US10428074, Example 121 BDBM260477 US9527851, example 48
US10799518, Compound 121 US10434112, Compound 121 US10208071, Compound 121 BDBM350659 (2S)-2-{[(4- iodophenyl)carbamoyl]amino}- 4-methylpentanoic acid
BDBM106208 US8575197, II-121
BDBM115976 US8633183, E-121
BDBM122651 US8735386, I-121
BDBM129638 US8815934, No. 121
BDBM131900 US8835436, Example 121
BDBM174331 US9688669, Example 121
BDBM182224 US9145391, 4-121
BDBM193396 US9670208, Example 121
BDBM230277 US9340500, I-121
BDBM258280 US9493485, 9-121
BDBM270400 US10059667, Example 121
BDBM275560 US9884814, Compound 121
BDBM279296 US10035760, Example 121
BDBM282626 US9884828, 2-121
BDBM288813 US10092551, Example 121
BDBM288984 US10092563, Compound 121
BDBM290540 US10099993, Compound 121
BDBM304821 US10144731, Example 121
BDBM309498 US9603833, Example 121
BDBM313430 US10167270, Example 121
BDBM314007 US10167299, Example 121
BDBM317348 US9617282, Example 121
BDBM326424 US9662327, Compound 121
BDBM331700 US9725465, Example 121
BDBM337499 US9745321, Compound 121
BDBM339676 US10202339, Compound 121
BDBM340048 US9758483, Compound 121
BDBM341887 US9771320, Example 121
BDBM347915 US9790221, Compound 121
BDBM348202 US9790228, Compound 121
BDBM350812 US10208081, Example 121
BDBM351876 US9796716, Compound 121
BDBM352314 US9802939, I-121
BDBM357165 US10214512, Example 121
BDBM357395 US10214519, Example 121
BDBM358807 US10214544, Example 121
BDBM362332 US9834548, Example 121
BDBM369614 US10233152, Example 121
BDBM371897 US10239870, Example 121
BDBM374913 US10251893, Cpd 121
BDBM380513 US9926318, 1-121
BDBM381764 US10272079, Compound 121
BDBM383979 US10280166, Compound 121
BDBM384435 US9932325, Example 121
BDBM386992 US9938222, Example 121
BDBM387297 US10292981, Example 121
BDBM387973 US10294229, Example 121
BDBM390234 US9951086, Example 121
BDBM390857 US9957263, Example 121
BDBM392923 US10301306, Example 121
BDBM393504 US9969687, Compound 121
BDBM393833 US9969726, Example 121
BDBM397910 US9994552, Compound 121
BDBM403848 US10336717, Compound 121
BDBM405946 US10351558, Example 121
BDBM410908 US10383880, Example 121
BDBM413937 US10421756, Compound 121
BDBM419783 US10464919, Example 121
BDBM435612 US10570121, Example 121
BDBM437687 US10617706, Example 121
BDBM438128 US10597367, Example 121
BDBM438300 US10618897, Example 121
BDBM439590 US10633379, Example 121
BDBM442943 US10653688, Compound 121
BDBM450003 US10703755, Example 121
BDBM453063 US10711036, Compound 121
BDBM458026 US10752596, Example 121
BDBM458223 US10752615, Compound 121
BDBM467135 US10800784, Example 121
BDBM469346 US10807985, Compound 121
BDBM475071 US10849901, Compound 121
BDBM479192 US10894789, Compound 121
BDBM480907 US10906888, Example 121
BDBM483377 US10919902, Compound 121
BDBM487567 US10954193, Example 121
BDBM489867 US10966980, Example 121
BDBM493420 US10981917, Example 121
BDBM498296 US11014911, Example 121
BDBM500109 US11021457, Compound 121
BDBM500262 US11021467, Compound 121
BDBM509014 US11071730, Example 121
BDBM509377 US11072611, Compound 121
BDBM510667 US11078186, Example 121
BDBM512528 acs.jmedchem.1c00409_ST.121
BDBM514895 US11098041, Example 121
BDBM515254 US11098058, Example 121
BDBM515808 US11053225, Compound 121
BDBM516031 US11053226, Example 121
BDBM520060 US11142527, Example 121
BDBM520837 US11149018, Example 121
BDBM522935 US11161850, Example 121
BDBM523390 US11136296, Example 121
BDBM524836 US11168093, Example 121
BDBM525703 US11174250, Example 121
BDBM527508 US11186582, Example 121
BDBM528251 US11180494, Example 121
BDBM530824 WO2022076496, Example 121
BDBM533625 US11225469, Compound 121
BDBM537141 US11247989, Example 121
BDBM538279 US11254663, Example 121
BDBM538780 US11254668, Example 121
BDBM540198 US11261186, Example 121
BDBM541526 US11267811, Example 121
BDBM541914 US11267824, Example 121
BDBM548130 WO2022091056, Example 121
BDBM553791 US11319304, Compound 121
BDBM554095 US11325916, Example 121
BDBM555268 US11337971, Compound 121
BDBM555445 US11344549, Example 121
BDBM556238 US11345699, Example 121
BDBM558082 US11365191, Example 121
BDBM560806 US11384090, Compound 121
BDBM561232 US11390610, Example 121
BDBM565072 US11414395, Example 121
BDBM569347 US11427563, Compound 121
BDBM570089 US11427591, Compound 121
BDBM580776 US11492346, Example 121
BDBM582941 US11547697, Compound 121
BDBM582995 US11548892, Compound 121
BDBM584373 US11524968, Example 121
BDBM585249 US11530197, Compound 121
BDBM586396 US11530244, Compound 121
BDBM589150 US11548900, Example 121
BDBM589867 US11559538, Example 121
BDBM591159 US11566003, Compound 121
BDBM592470 US11572368, Compound 121
BDBM594326 US11584747, Example 121
BDBM594832 US11584755, Example 121
BDBM596746 US11596639, Example 121
BDBM603148 US11649255, Example 121
BDBM607093 US11685744, Example 121
BDBM612859 US11725000, Compound 121
BDBM614108 US11744824, Example 121
BDBM615330 US20230271949, Example 121
BDBM619797 US20230295157, Example 121
BDBM620261 US20230295171, Example 121
BDBM622161 US20230312550, Example 121
BDBM622444 US20230312576, Compound 121
BDBM625096 US20230322747, Compound 121
BDBM626473 US11787780, Example 121
BDBM628866 US20230339890, Compound 121
BDBM629007 US20230339891, Example 121
BDBM629825 US20230340011, Example 121.
BDBM631256 US11802133, Example 121
BDBM631851 US20230348426, Example 121
BDBM632739 US20230348450, Example 121
BDBM634672 US11814367, Compound 121
BDBM638018 US11834453, Example 121
BDBM638526 US11834467, Example 121
BDBM641046 US20230399342, Example 121
BDBM641227 US11845723, Example 121
BDBM643877 US11866405, Example 121
BDBM648153 US20240025922, Example 121
BDBM648728 US20240034729, Compound 121
BDBM649432 US20240034743, Compound 121
BDBM649884 US20240043403, Example 121
BDBM655274 US11912703, Example 121
BDBM657304 US11926628, Example 121
BDBM658625 US20240083908, Example 121
BDBM659004 US20240092758, Example 121
BDBM660595 US20240092819, Compound 121
BDBM666088 US20240116946, Example 121
BDBM668825 US11964953, Example 121
BDBM669138 US11964973, Example 121
BDBM670177 US11970474, Example 121
BDBM675364 US20240158414, Example 121
BDBM676653 US20240166643, Example 121
BDBM679608 US20240182453, Example 121
BDBM681433 US20240199571, Compound 121
BDBM681562 US20240199605, Example 121
BDBM684050 US20240218021, Example 121
BDBM685385 US20240239774, Example 121
BDBM686676 US20240246937, Example 121
BDBM690603 US12065430, Example 121
BDBM695400 US12083101, Example 121
BDBM696125 US20240300936, Example 121
BDBM699688 US12110299, Example 121
BDBM700020 US20240335442, Compound 121
BDBM702159 US20240360134, Example 121
BDBM702382 US20240360148, Example 121
BDBM702767 US20240360157, Example 121
BDBM703175 US20240368104, Example 121
BDBM706597 US20240383915, Example 121
BDBM712304 US20250011311, Example 121
BDBM712861 US20250019374, Compound 121
BDBM713885 US12202835, Example 121
BDBM714957 US20250026748, Compound 121
BDBM715636 US20250026766, Example 121
BDBM716683 US20250034135, Compound 121
BDBM718266 US20250042889, Example 121
BDBM723008 US20250059220, Compound 121
BDBM723547 US20250064789, Compound 121
BDBM725371 US20250074891, Compound 121
BDBM725914 US20250074911, Example 121
BDBM730399 US20250120927, Compound 121
BDBM730908 US20250122183, Example 121
BDBM732406 US20250115563, Compound 121
BDBM732991 US20250115583, Example 121
BDBM733500 US20250115600, Compound 121
BDBM734578 US20250129067, Compound 121
BDBM735103 US20250129078, Compound 121
BDBM735534 US20250129103, Compound 121
BDBM737392 US20250136596, Example 121
BDBM738914 US20250145633, Example 121
BDBM740817 US12303509, Example 121
BDBM741277 US20250161307, Example 121
BDBM745642 US12319655, Example 121
BDBM746951 US20250179047, Example 121
BDBM749068 US20250188079, Compound 121
BDBM749500 US12331033, Example 121
BDBM750469 US20250195475, Example 121
BDBM751855 US20250197382, Compound 121
BDBM752999 US20250197428, Example 121
BDBM753711 US20250206717, Example 121
BDBM755488 US20250214932, Example 121
BDBM757483 US12357603, Example 121
BDBM759532 US20250236608, Example 121
BDBM761704 US12378224, Example 121
BDBM764787 US20250257059, Example 121
BDBM765493 US12391697, Example 121
MTH1 inhibitor, 121 BDBM227634
US10005792, Compound 121 BDBM401762
US10022354, Example 121 BDBM281181
US10022461, Compound 121 BDBM281651
US10040791, Example 121 BDBM278659
US10065950, Example 121 BDBM272279
US10112899, Example 121 BDBM294642
US10112929, Example 121 BDBM295397
US10130619, Example 121 BDBM300403
US10131675, Example 121 BDBM301635
US10137122, Compound 121 BDBM303245
US10138222, Example 121 BDBM303396
US10172856, Example 121 BDBM315473
US10174037, Example 121 BDBM320715
US10189816, Compound 121 BDBM324128
US10202377, Compound 121 BDBM346289
US10221177, Compound 121 BDBM361758
US10227329, Compound 121 BDBM367709
US10227338, Example 121 BDBM368334
US10239843, Example 121 BDBM371014
US10435369, Example 121 BDBM414234
US10450301, Example 121 BDBM419042
US10457654, Example 121 BDBM417259
US10457703, Example 121 BDBM419459
US10508105, Compound 121 BDBM422772
US10544136, Compound 121 BDBM427390
US10556885, Compound 121 BDBM430312
US10562902, Compound 121 BDBM434715
US10577368, Compound 121 BDBM434829
US10604514, Compound 121 BDBM439233
US10618903, Example 121 BDBM438493
US10626095, Example 121 BDBM610813
US10654833, Compound 121 BDBM443207
US10660877, Example 121 BDBM443538
US10676433, Compound 121 BDBM450490
US10709709, Example 121 BDBM451294
US10730832, Example 121 BDBM453524
US10766903, Example 121 BDBM462509
US10807959, Example 121 BDBM468709
US10844044, Example 121 BDBM473309
US10894782, No 121 BDBM478268
US10899735, No. 121 BDBM479662
US10968215, Compound 121 BDBM490247
US11008314, Compound 121 BDBM498037
US11021493, Example 121 BDBM501202
US11028090, Example 121 BDBM502248
US11045457, Example 121 BDBM506521
US11053213, Example 121 BDBM514378
US11098063, Example 121 BDBM515614
US11136311, Compound 121 BDBM523631
US11142525, Example 121 BDBM519720
US11203591, Example 121 BDBM529713
US11242337, Example 121 BDBM536019
US11292791, Example 121 BDBM546848
US11299480, Example 121 BDBM549095
US11306071, Compound 121 BDBM549546
US11312722, Compound 121 BDBM551831
US11352340, Example 121 BDBM557069
US11352363, Example 121 BDBM557549
US11365196, Compound 121 BDBM558625
US11377438, Example 121 BDBM560079
US11377439, Example 121 BDBM560284
US11414387, Compound 121 BDBM564946
US11420970, Example 121 BDBM567920
US11433053, Example 121 BDBM570234
US11458138, Example 121 BDBM574292
US11518761, Example 121 BDBM582050
US11530193, Example 121 BDBM585206
US11534441, Compound 121 BDBM587412
US11548903, Example 121 BDBM589192
US11591331, Example 121 BDBM595791
US11591336, Compound 121 BDBM596259
US11642348, Compound 121 BDBM601718
US11660293, Example 121 BDBM604018
US11667652, Example 121 BDBM605327
US11680060, Example 121 BDBM606047
US11685745, Example 121 BDBM607200
US11691968, Example 121 BDBM608100
US11697648, Example 121 BDBM608552
US11725010, Example 121 BDBM613230
US11773078, Example 121 BDBM621369
US11793823, Compound 121 BDBM627549
US11795165, Compound 121 BDBM628202
US11866430, Example 121 BDBM644198
US11897851, Compound 121 BDBM537005
US11912668, Example 121 BDBM653841
US11912682, Compound 121 BDBM654022
US11912686, Compound 121 BDBM654176
US12128028, Example 121 BDBM701725
US12173018, Example 121 BDBM708193
US12194050, Example 121 BDBM712611
US12263171, Example 121 BDBM729964
US12304897, Compound 121 BDBM740999
US12338220, Example 121 BDBM753129
US12351556, Compound 121 BDBM756227
US12378231, Example 121 BDBM762501
US12384753, Example 121 BDBM763098
US20230271941, Compound 121 BDBM615047
US20230278998, Compound 121 BDBM616803
US20230286943, Example 121 BDBM617653
US20230286970, Compound 121 BDBM618276
US20230322846, Example 121 BDBM625717
US20230339981, Example 121 BDBM629433
US20230348456, Compound 121 BDBM633100
US20230357253, Compound 121 BDBM634230
US20230364079, Example 121 BDBM635697
US20230365546, Compound 121 BDBM636338
US20230365556, Compound 121 BDBM636506
US20240018138, Compound 121 BDBM645647
US20240025884, Example 121 BDBM646910
US20240025919, Compound 121 BDBM647889
US20240043427, Example 121 BDBM650035
US20240043448, Example 121 BDBM651058
US20240067631, Compound 121 BDBM655960
US20240091200, Example 121 BDBM658830
US20240092770, Compound 121 BDBM659511
US20240101572, Example 121 BDBM661512
US20240116877, Example 121 BDBM664852
US20240116922, Example 121 BDBM665819
US20240132480, Example 121 BDBM669720
US20240140931, Compound 121 BDBM670544
US20240158369, Compound 121 BDBM674857
US20240190854, Example 121 BDBM688625
US20240245673, Example 121 BDBM686009
US20240246964, Compound 121 BDBM687120
US20240247015, Example 121 BDBM688009
US20240262804, Example 121 BDBM689661
US20240287022, Example 121 BDBM693673
US20240287079, Example 121 BDBM693952
US20240294551, Example 121 BDBM694955
US20240316047, Example 121 BDBM697338
US20240317691, Compound 121 BDBM697988
US20240409609, Compound 121 BDBM707583
US20250042896, Compound 121 BDBM718801
US20250059156, Compound 121 BDBM721512
US20250059174, Example 121 BDBM721858
US20250084074, Example 121 BDBM726807
US20250115591, Example 121 BDBM733261
US20250122174, Example 121 BDBM730539
US20250127903, Compound 121 BDBM733825
US20250136586, Example 121 BDBM737159
US20250145606, Example 121 BDBM738562
US20250145642, Compound 121 BDBM739626
US20250154115, Compound 121 BDBM739911
US20250171447, Ex-121 BDBM745308
US20250179055, Compound 121 BDBM747104
US20250188057, Compound 121 BDBM748772
US20250197368, Example 121 BDBM751609
US20250197406, Example 121 BDBM752530
US20250215013, Example 121 BDBM756629
US20250230159, Example 121 BDBM758476
US20250243180, Compound 121 BDBM761130
US8501732, I-121 BDBM100561
US8575203, I-121 BDBM105354
US8633183, D-121 BDBM115742
US8653087, III-121 BDBM117441
US8940720, I-121 BDBM142918
US8962608, 28-121 BDBM147802
US9056865, A-121 BDBM162994
US9150519, 1-121 BDBM183718
US9150578, I-121 BDBM184491
US9247759, 5-121 BDBM211174
US9359338, Exe. 121 BDBM235511
US9527851, example 121 BDBM202503
US9546153, ex. 121 BDBM209429
US9573958, Compound 121 BDBM290194
US9586900, Example 121 BDBM294217
US9745283, Example 121 BDBM336692
US9758538, Example 121 BDBM340432
US9763922, Example 121 BDBM340592
US9873693, Compound 121 BDBM366198
US9926281, Compound 121 BDBM379620
US9951027, 3-121 BDBM389487
WO2022076495, EXAMPLE 121 BDBM530690
WO2022081807, Example 121 BDBM534014
WO2022086828, Example 121 BDBM534388
WO2023003973, Compound 121 BDBM581914
US10646492, Example 121 (2R)-1-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl]-5-chloro-2-methoxy-6-methylphenyl}azetidin-1-yl)-1-oxopropan-2-ol trifluoroacetate BDBM261098 US10092570, Example 121 US9932341, Example 121 US11433071, Example 121 US10376513, Example 121 US9730939, Example 121 US9707233, 121
2-[5-[[4-fluoro-2-[2-(4- fluorophenyl)ethyl]phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid US9604961, Example 121 US9908865, Example 121 US10173996, Example 121 US9714230, 121 BDBM264036
US10968223, Compound 121 2-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2- yl]pyridine US10766897, Compound 121 BDBM389950 US9951068, Compound 121
US10137124, Example 121 US10112942, Example 121 BDBM296387 US10555944, Example 121 US10953005, Example 121 US10172851, Example 121 6-((R)-2- hydroxypropoxy)-4- (6-(4-((R)-2- methoxy-2- phenylacetyl) piperazin-1-yl) pyridin-3- yl)pyrazolo[1,5- a]pyridine-3- carbonitrile
BDBM124947 US9682141, 225 US9682141, 121
BDBM239937 US9403767, 123 US9403767, 121
BDBM244369 US9550763, Compound I-121
BDBM323384 US9630956, Compound I-121
BDBM332831 US10196390, Compound I-121
BDBM35839 pyrimidine-4-carboxamide, 121
BDBM359353 US10221129, Example CA-121
BDBM375902 US9914731, Ex. No. 121
BDBM388424 US10294246, Compound No. 121
BDBM398392 US10323018, Compound I-121
BDBM423233 US10501449, Example 121-I
BDBM465470 US10793568, Compound I-121
BDBM482054 US10913753, Compound I-121
BDBM482973 US10919885, Compound No. 121
BDBM50547007 CHEMBL4747960 US11752138, Compound 121
BDBM50547880 CHEMBL4789274 US20230271945, Compound 121
BDBM50548941 US20230365568, Compound 121 CHEMBL4741217
BDBM50583991 US20250051337, Compound 121 CHEMBL5092052
BDBM513363 US11091472, Compound S-121
BDBM532867 US11214565, Example D-121
BDBM540795 US11261211, Compound SA-121
BDBM544228 US11285156, Ex.# 121-1
BDBM547902 WO2022090481, Example I-121
BDBM548725 WO2022098806, Compound 1-121
BDBM548860 WO2022098806, Compound 2-121
BDBM566752 US11420958, Ex. No. 121
BDBM581798 US11512080, Compound I-121
BDBM601841 US11643396, Example SG2-121
BDBM602108 US11643417, Ex. No. 121
BDBM607959 US11691963, Example I-121
BDBM609633 US11702418, Example 12-121
BDBM638886 US20230390274, Compound A-121
BDBM657900 US20240083872, Compound I-121
BDBM665191 US20240116892, Compound I-121
BDBM673902 US20240150321, Compound I-121
BDBM678285 US20240174690, Example II-121
BDBM692470 US20240270732, Compound I-121
BDBM715505 US20250026765, Compound I-121
BDBM722241 US20250059174, Example 281-121
BDBM727260 US20250090540, Example I-121
BDBM728513 US20250092056, Compound I-121
BDBM734884 US20250129069, Compound I-121
BDBM741354 US20250162989, Compound I-121
BDBM741945 US20250163057, Compound I-121
BDBM744548 US20250170126, Compound I-121
BDBM756174 US20250214997, Compound E-121
CHEMBL3426233 BDBM50086442 US10266537, Compound 121
CHEMBL4217787 BDBM50459716 US10836764, Compound 121
CHEMBL4518460 US11401286, Example 121 BDBM50524999
CHEMBL4522471 BDBM50527988 US11634404, Compound 121
CHEMBL4578978 US10829446, Compound 121 BDBM50527350
US10000476, Compound I-121 BDBM400762
US10144742, Compound I-121 BDBM305959
US10150728, Example I-121 BDBM306908
US10189809, Compound I-121 BDBM323852
US10435400, Compound Z-121 BDBM414575
US10487086, Example I-121 BDBM420090
US10597366, Compound 121 BDBM50450489 CHEMBL4163733
US10640495, Example I-121 BDBM441207
US10774071, Example B-121 BDBM461654
US10829487, Example I-121 BDBM472638
US10961247, Ex. No. 121 BDBM489513
US11026937, Compound I-121 BDBM501545
US11136327, Example I-121 BDBM523950
US11198695, Example I-121 BDBM528910
US11260049, Ex. 121 CHEMBL4547537 BDBM50521192
US11274090, Example 121-racemic BDBM542361
US11339144, Compound I-121 BDBM554671
US11407736, Compound I-121 BDBM562944
US11492341, Compound I-121 BDBM580626
US11555012, Compound I-121 BDBM589372
US11578084, Compound I-121 BDBM593838
US11685732, Compound I-121 BDBM606474
US11691962, Compound 1-121 BDBM607723
US11753403, Compound I-121 BDBM617153
US11964949, Compound OTB-121 BDBM668539
US12331046, Compound I-121 BDBM750015
US20230295130, Example T-121 BDBM619488
US20230399319, Example 2-121 BDBM640574
US20240101552, Compound L-121 BDBM661356
US20240101572, Example 2-121 BDBM661851
US20240207300, Compound 121 BDBM682393 BDBM682383
US20240308995, Example 1-121 BDBM697041
US20240374587, Example II-121 BDBM704318
US20250042857, Example B-121 BDBM718006
US8674113, 90 US8674113, 121 BDBM118833
US8912224, 121 US8912224, 120 BDBM140689
US9265773, 121 US9265773, 122 BDBM208178
US9365576, 218 US9365576, 121 BDBM236368
US9394297, 122 BDBM238491 US9394297, 121
US9394331, 121 US9394331, 120 BDBM240858
US9468661, 36 US9468661, 121 BDBM254458
US9725442, Compound I-121 BDBM330590
US9790235, Number I-121 BDBM348868
US9796700, Compound I-121 BDBM351031
N-[(2-fluoro-3-methoxyphenyl)methyl]-2-methyl-1-({4-[(2-oxopyridin-1- yl)methyl]phenyl}methyl)imidazole-4-carboxamide US10364238, Example 121 BDBM408801 US11001578, Example 121 US11084809, Example 121 US11198691, Example 121
US11618744, Example 121 US10851083, Example 121 1-(5-Benzylcarbamoyl-1H-benzoimidazol-2-yl)-1H- BDBM475509
US11130759, Cpd. No. 121 US11084798, Cpd No 121 BDBM507902 US11046691, Compound 121 1-pyrimidin-2-yl-4-[(2,2,2-trifluoro- ethyparnino]-7-(trifluoromethyphydro- quinazolin-2-one
BDBM154849 US8999957, Table 3, Compound 121
BDBM221834 US9314468, Table 7, Compound 121
BDBM433633 US10562878, Compound cis 121 E2
BDBM498171 US11013745, Compound SL-ZYE-121
BDBM726293 US12247004, Compound ANASIA-121-2
US10196373, Compound BP2-121 BDBM50440941 CHEMBL2431940
US10562878, Compound trans 121 E1 BDBM433634
US10562878, Compound trans 121 E2 BDBM433635
US10954217, Example KTL-01-121 BDBM488121
US11427593, Compound ZB-BD-121 BDBM570125
US11591319, ID lqr-9-121 BDBM595543
US12247004, Compound ANASIA-121-1 BDBM726292
US20230348487, Example LS 6-121 BDBM633223
US9944618, Compound ID No. 121 BDBM388586
US10017468, Compound 121 US11072582, Compound 121 US10781171, Compound 121 (2S,5R)-5-(2-chlorophenyl)-1-(4-(6-methylpyridin-3-yl)benzoyl)pyrrolidine-2-carboxylic acid BDBM403861
US10881652, Example 121 BDBM305105 US10172845, Example 121 US10441581, Example 121 US10144734, Example 121 US11648243, Example 121 2-(4-chlorophenyl)- N-(1-(5-(3-cyano-6-(2- hydroxy-2- methylpropoxy)pyrazolo [1,5-a]pyridin-4-yl) pyridin-2-yl)-4- methylpiperidin-4-yl)- 2-methylpropanamide 2,2,2-trifluoroacetate
US11078199, Cpd 121 BDBM287541 US10294223, Cpd No. 121 US9815834, Compound 121 8-(2-((1-acryloylazetidin-3-yl)(2-methoxyethyl)amino)ethyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8H)-one US9567334, Example 121
BDBM329913 (rac)-((1R,2R,3S,4R)-2,3-dihydroxy-4-{[2-(6-phenylpyrazin-2-yl)pyrazolo[1,5- US9663525, Compound I-121 US10202389, Compound I-121 US9796725, Compound I-121
BDBM386166 US11292766, Example 121 US10508083, Example 121 N-(cis-2-(((cis-4- phenylcyclohexyl)oxy)methyl)-1- (tetrahydro-2H-pyran-4- ylcarbonyl)piperidin-3- yl)methanesulfonamide US10287305, Example 121
BDBM219305 US9303033, X18, Table 33A, Compound 121
BDBM219447 US9303033, R24, Table 37A, Compound 121
BDBM268719 US9718825, Example 121 US9718825, Example 122
BDBM270399 US10059667, Example 121 US10059667, Example 120
BDBM330940 US9725445, 3-121 US9725445, 3-122
BDBM360205 US9828339, Example 121 (S)-(1-methyl-
BDBM435611 US10570121, Example 120 US10570121, Example 121
BDBM515245 US11098058, Example 112 US11098058, Example 121
BDBM550482 US11306098, Example 48 US11583538, Example 121
BDBM573937 US11453697, Example 123 US11453697, Example 121
BDBM594325 US11584747, Example 120 US11584747, Example 121
BDBM625488 US20230322789, Example 88 US20230322789, Compound 121
BDBM625521 US20230322789, Example 121 US20230322789, Compound 154
BDBM644707 US11866450, Compound 121 US11866450, Compound 120
BDBM646473 US11878973, Example 121 US11878973, Example 122
BDBM665437 US20240116910, Compound 282 US20240116910, Compound 121
BDBM710648 US12187701, Compound FMF-04-121-1
BDBM99343 US8497281, 121 US9120769, 54 US9663470, 54
US10059705, II-122 US10059705, II-121 BDBM270726
US10099993, Compound 114 US10099993, Compound 121 BDBM290533
US10174037, Example 121 US10174037, Example 120 BDBM320714
US10227338, Example 121 US10227338, Example 98 BDBM368311
US11306071, Compound 121 BDBM549540 US11306071, Compound 116
US11427563, Compound 81 BDBM569325 US11427563, Compound 121
US11492346, Example 120 BDBM580775 US11492346, Example 121
US11912703, Example 121 US11912703, Example 91 BDBM655216
US11999676, Compound 122 US11999676, Compound 121 BDBM679258
US20230357269, Example 121 9,14-dioxa-4,5,11,19,20- BDBM634436
US20240174662, Example 147 US20240174662, Example 121 BDBM677457
US20250025443, Compound 121 US20250025443, Example 15 BDBM713982
US20250025443, Example 121 US20250025443, Compound 246 BDBM714087
US8530652, 121 US8530652, 69 BDBM101542 US8530494, 207
US8802673, 135 US8802673, 134 US8802673, 121 BDBM129479
US9247759, 5-58 US9247759, 5-121 BDBM211134
US9409866, 110 US9409866, 121 BDBM240395 US9409866, 120
US9663469, 102 US9663469, 121 US9663469, 120 BDBM327563
US9617225, Example 121 2-Methoxy-4-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenol BDBM316293 US10294218, Example 121
US9624243, 121 US10370388, Compound 121 (2S,4S)-4-((benzylthio)methyl)-1-(2,2-diphenylacetyl)pyrrolidine-2-carboxylic acid BDBM318806
6-(4-(3-chloro-4-fluorophenyl)-1-(3,3- difluorocyclobutyl)-1H-imidazol-5-yl)imidazo[1,2- a]pyridine-3-carboxamide US11352360, Example 121' US9884868, Example 121' BDBM282916 US10287295, Example 121'
US10851110, Example 121 US11466017, Example 121 US10280171, Example 121 (4-Amino-1-(3-(2-chloro-6-fluorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl)-piperidin-4-yl)methanol BDBM384201
US11066365, Example 121 (R)-N-(1-cyanopyrrolidin- 3-yl)-3-fluoro-5-(1-methyl- 1H-pyrrolo[2,3-b]pyridin-5- yl)picolinamide US10343992, Example 121 US10689345, Example 121 BDBM404469
US11498926, Example 121 US9624241, Example 121 7-(3,5-Dimethylisoxazol-4-yl)-1-methyl-4-phenyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one BDBM318577 US10464947, Example 121
3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-ethyl-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one US10131667, Example 121 US11053246, Example 121 BDBM301305 US9611267, Example 121
BDBM400139 US10874640, Compound 121 US20230270719, Compound 121 7-(2-((1-carbamoyl-3,3-difluorocyclobutyl)amino)-2-oxoacetyl)-N-(3,4-difluorophenyl)-6-methyl-2,3-dihydro-1H-pyrrolizine-5-carboxamide US10328053, Compound 121
US10202381, Example 121 US10208039, Example 121 2-(4-((4-isopropylphenyl)amino) phenoxy)pyrido[3,4-d]pyrimidin-4-ol BDBM347114
N-[4-(Methoxymethyl)tetrahydro-2H-pyran-4-yl]-4-[7-(1-quinolin-6-ylcyclopropyl)imidazo[1,2-b][1,2,3]triazin-2-yl]benzamide US10738052, Example 121 US11261191, Example 121 BDBM388791 US9944645, 121
US12129248, Compound ACV-42 ACV-2-121 BDBM701952
US11319287, Example 121 US10669234, Example 121 (S)-2-(4-(2-aminopyrimidin- 5-yl)indoline-1- carbonyl)pyrrolidine-1- carbonitriie BDBM445164
N-(3-fluorophenyl)-N-({5-[5- (trifluoromethyl)-1,3,4-oxadiazol-2-yl]-1,3- thiazol-2-yl}methyl)ethane-1-sulfonamide US20240269137, Compound I-121 BDBM593430 US11578066, Compound I-121 US20230381148, Compound I-121
US12065446, Example 121 US10934310, Ex # 109 US11319329, Ex # 121 US10934310, Ex # 121 BDBM485275 N-((1RS,3RS)-3-Acrylamidocyclopentyl)-4-oxo-5-(4- phenoxyphenyl)-4,5-dihydro-3H-1-thia-3,5,8-triazaacenaphthylene- 2-carboxamide
4-[5-[4-(dimethylamino)piperidin-1- yl]-8-(3-hydroxy-2,3-dihydro-1H- inden-5-yl)imidazo[1,2-c]pyrimidin- 7-yl]benzonitrile US9944647, Example 121 BDBM389012 US10800779, Example 121 US11401272, Example 121
US11608338, Example 121 US10457677, Example 121 US10975075, Example 121 1-(1,3-Dimethyl-1H-pyrazol- 4-yl)-7-methoxy-3-methyl-8- (1H-pyrazol-3-yl)-1,3- dihydroimidazo[4,5-c]- quinolin-2-one BDBM418526
BDBM510261 US11439633, Example 121 US11077100, Example 121 (5S,8RS)-N-(2,3-dichloro benzyl)-5-fluoro-8- hydroxy-5,6,7,8- tetrahydroquinoline- 5-carboxamide
US10214507, Compound 121 BDBM356942 US10759777, Compound 121 (R)-1-((R)-3-(9H- carbazol-9-yl)-2- hydroxypropyl)-3- fluoropyrrolidin-2- one
US11155532, Example 121 US9994546, Example 121 US10676457, Example 121 N,N-dimethyl-2-[3-(4-{[(1R,2S)-2-phenylcyclopropyl]amino}piperidin-1-yl)-1-(tetrahydro-2H-pyran-4-yl)azetidin-3-yl]acetamide BDBM397622
US11548890, Compound I-121 7-[[5-[(3R)-3- hydroxy-1- piperidyl]-2- pyridyl]amino]- 4-(1-methylpyrrolo [2,3-b]pyridin- 4-yl)isoindolin- 1-one US11078201, Compound I-121 US11021481, Compound I-121 BDBM500462
BDBM239839 Roche-Dataset for PDE10A, Compound 50 US9394311, 121
BDBM704333 US20240374587, Example I'-123 US12227509, Example I-121
US10640495, Example I-121 BDBM441205 US10640495, Example I-118
US11845724, Compound I-121 (S)-4-fluoro-N- BDBM642006
1-(6-(1-(6-isopropylpyridin-2-yl)-1H-indazol-6-yl)pyridin-2-yl)ethanamine US10577367, Example 121 US10246456, Example 121 BDBM374112
US10479784, Compound IA-121 5-(2-isopropylsulfonylphenyl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)pyrazin-2-amine BDBM420617 US10961232, Compound IA-121
US9745328, Compound 121 US9884878, Compound 121 (trans)-4'-(5-Aminopyrazin-2-yl)-3'-fluoro-N-[2- (hydroxymethyl)cyclohexyl]biphenyl-2- sulfonamide BDBM283248
3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- dimethyl-1H-pyrazol-4-yl)-1- ((2-methylpyrimidin-4- yl)methyl)-3,4- dihydropyrido[4,3-d]pyrimidin- 2(1H)-one BDBM262076 US9708318, 121 US10251892, Example 121 US11173162, Example 121
(S,E)-4-(8-amino-3-(1-(4- methoxybut-2-enoyl)piperidin-2- yl)imidazo[1,5-a]pyrazin-1-yl)-N-(4- propylpyridin-2-yl)benzamide US10934296, Example 121 US9758524, Example 121 US10239883, Example 121 BDBM340184
US10392376, Example 121 BDBM411570 US11434233, Example 121 (R)-1-((2-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl)-6-(3-methyl- morpholino)pyrimidin-4- yl)imino)tetrahydro-1H- 1lambda6-thiophene 1-oxide US10800769, Example 121
US10450296, Example 121 N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-5-fluoro-3-(7-oxa-2-azaspiro[3.5]nonan-2-yl)quinoline-8-carboxamide US11053215, Example 121 BDBM376790 US9920032, Example 121
BDBM327984 US10377742, Compound 121 5-(1-benzyl-1H-1,2,3- triazol-4-yl)-N-(1-(4- cyanobenzyl)piperidin-4- yl)picolinamide US9663496, Compound 121
US10167281, Compound 121 BDBM267202 N-[2-(4-cyclopropyl-1,3-thiazol-5-yl)-2-(4,4-difluoropiperidin-1-yl)ethyl]quinoline-5-carboxamide US9718812, 121
US10617680, Example 121 US11020380, Example 121 BDBM437387 5-(1-benzyl-1H-pyrazol-4-yl)-4-(isoxazol-3-yl)-1- methylpyridin-2(1H)-one
US11479551, Example 4-121 US11492351, Example 4-121 BDBM578993 4-(aminomethyl)-6-(5-(quinolin-8- yloxy)pyridin-3-yl)phthalazin-1(2H)-one
BDBM368706 US10227350, Compound 122 US10227350, Compound 145 US10227350, Compound 121
US10508105, Compound 121 US10508105, Compound 134 BDBM422708 US10508105, Compound 57
US10577336, Example 122 US10071974, Example 121 US10071974, Example 122 BDBM276010
US10695337, Example 120 US9999619, Example 121 US11285140, Example 120 BDBM400366
US11866405, Example 121 US11866405, Example 120 US11866405, Example 123 BDBM643875
US20230382904, Compound 131 US20230382904, Compound 121 US20230382904, Compound 132 BDBM637201
US8168651, Compound TABLE 16.121 BDBM165453 US9062043, Table 13, Compound 121