Target (2)
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Article Title (73)
Assay (18)
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2-(piperazin-1-yl)nicotinamide BDBM50027028 2-Piperazin-1-yl-nicotinamide CHEMBL47688
BDBM213227 Nicotinamide adenine dinucleotide (NAD)
CHEMBL561554 BDBM50293641 6-Phenylethynyl-nicotinamide
Nicotinamide hydrochloride analog, 6a BDBM86768
Nicotinamide hydrochloride analog, 6b BDBM86769
Nicotinamide hydrochloride analog, 6c BDBM86770
Nicotinamide hydrochloride analog, 6d BDBM86771
5-(1,4-diazepan-1-yl)nicotinamide CHEMBL70737 BDBM50088432 5-[1,4]Diazepan-1-yl-nicotinamide
N-(4-aminobiphenyl-3-yl)nicotinamide N-(4-amino-biphenyl-3-yl)-nicotinamide BDBM50232035 CHEMBL255805
CHEMBL600579 N-(2-Morpholinoethyl)nicotinamide BDBM50307206
N-(2-aminophenyl)nicotinamide CHEMBL236678 BDBM50220259
N-(3-Morpholinopropyl)nicotinamide BDBM50307193 CHEMBL599391
N-(3,3-diphenylpropyl)nicotinamide BDBM50297413 N-(3,3-diphenyl-propyl)-nicotinamide N-(3,3-diphenylpropyl)pyridine-3-carboxamide CHEMBL560537
8-Bromo-Nicotinamide adenine dinucleotide BDBM50343898 CHEMBL1775003
8-phenyl-Nicotinamide adenine dinucleotide BDBM50343899 CHEMBL1775004
BDBM152529 N-(coumarin-3-yl)nicotinamide (6)
BDBM50297410 CHEMBL563465 N-(2,2-Diphenyl-ethyl)-nicotinamide
BDBM51391 N-(4-acetamidophenyl)-6-chloro-nicotinamide
CHEMBL168418 N-Benzyl-2-phenoxy-nicotinamide BDBM50008705
CHEMBL1779843 N-Methyl-6-phenylethynyl-nicotinamide BDBM50344416
CHEMBL1779844 BDBM50344415 N-Isopropyl-6-phenylethynyl-nicotinamide
CHEMBL561479 N-(4,4-Diphenyl-butyl)-nicotinamide BDBM50297406
N-(3-Phenyl-propyl)-nicotinamide CHEMBL560538 BDBM50297409
2,6-Bis-(3-carbamimidoyl-phenoxy)-nicotinamide BDBM50077176 CHEMBL48206
2-Bromo-N-(2-morpholinoethyl)nicotinamide BDBM50307208 CHEMBL607864
2-Bromo-N-(3-morpholinopropyl)nicotinamide BDBM50307195 CHEMBL598373
2-Chloro-N-(2-morpholinoethyl)nicotinamide BDBM50307207 CHEMBL598814
2-Chloro-N-(3-morpholinopropyl)nicotinamide BDBM50307194 CHEMBL608436
5,6-Dichloro-N-(2-morpholinoethyl)nicotinamide BDBM50307191 CHEMBL589770
5,6-Dichloro-N-(3-morpholinopropyl)nicotinamide BDBM50307204 CHEMBL597764
6-(2-benzylisoindolin-5-yloxy)nicotinamide CHEMBL238362 BDBM50226248
6-(4-((benzylamino)methyl)phenoxy)nicotinamide BDBM50219916 CHEMBL238316
6-Hydroxy-N-(2-morpholinoethyl)nicotinamide CHEMBL596971 BDBM50307189
6-amino-N-(3,3-diphenylpropyl)nicotinamide BDBM50302479 CHEMBL568773
8-(4-Methoxyphenyl)-Nicotinamide adenine dinucleotide BDBM50343901 CHEMBL1775006
BDBM50219919 6-(4-((phenethylamino)methyl)phenoxy)nicotinamide CHEMBL238361
BDBM50226258 CHEMBL235154 6-(2-phenethylisoindolin-5-yloxy)nicotinamide
BDBM50293643 N-cyclopentyl-6-(2-phenylethynyl)nicotinamide CHEMBL551958
BDBM50293644 CHEMBL550624 N-cyclohexyl-6-(2-phenylethynyl)nicotinamide
BDBM50302480 CHEMBL567109 6-amino-N-(2,4-dichlorobenzyl)nicotinamide
BDBM50307186 CHEMBL598189 6-Methyl-N-(2-morpholinoethyl)nicotinamide
BDBM50307187 6-Fluoro-N-(2-morpholinoethyl)nicotinamide CHEMBL611061
BDBM50307196 2-Hydroxy-N-(3-morpholinopropyl)nicotinamide CHEMBL598578
BDBM50307198 CHEMBL598587 5-Bromo-N-(3-morpholinopropyl)nicotinamide
BDBM50307199 6-Methyl-N-(3-morpholinopropyl)nicotinamide CHEMBL590264
BDBM50307209 2-Hydroxy-N-(2-morpholinoethyl)nicotinamide CHEMBL597988
BDBM50307210 CHEMBL598187 4-Chloro-N-(2-morpholinoethyl)nicotinamide
BDBM50334325 CHEMBL1643020 6-Hydroxy-N-(4-methoxyphenyl)nicotinamide
BDBM50343900 CHEMBL1775005 8-(4-Chlorophenyl)-Nicotinamide adenine dinucleotide
BDBM50343902 8-(4-Methylphenyl)-Nicotinamide adenine dinucleotide CHEMBL1775007
CHEMBL1271417 N-benzyl-5-(4-chlorophenyl)nicotinamide BDBM50329212
CHEMBL238315 6-(4-(3-phenylpropylamino)phenoxy)nicotinamide BDBM50219920
CHEMBL576449 BDBM50302470 N-benzyl-6-(3,3,3-trifluoropropoxy)nicotinamide
CHEMBL597761 6-Hydroxy-N-(3-morpholinopropyl)nicotinamide BDBM50307202
CHEMBL598188 BDBM50307185 5-Bromo-N-(2-morpholinoethyl)nicotinamide
CHEMBL598586 4-Chloro-N-(3-morpholinopropyl)nicotinamide BDBM50307197
CHEMBL598791 6-Fluoro-N-(3-morpholinopropyl)nicotinamide BDBM50307200
CHEMBL610499 BDBM50307201 6-Chloro-N-(3-morpholinopropyl)nicotinamide
N-isopentyl-6-(2-phenylethynyl)nicotinamide BDBM50293642 CHEMBL551957
5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide CHEMBL1269882 BDBM50329211
5-(4-chlorophenyl)-N-(3,5-dimethylphenyl)nicotinamide CHEMBL1271416 BDBM50329213
6-(3,4,5-trimethoxybenzylamino)-N-(2-aminophenyl)nicotinamide CHEMBL424873 BDBM50187101
6-(4-(2-(benzylamino)ethyl)phenoxy)nicotinamide CHEMBL237066 BDBM50219925
6-(4-(3-(phenylamino)propyl)phenoxy)nicotinamide BDBM50219926 CHEMBL438134
6-(4-methoxyphenethylamino)-N-(2-aminophenyl)nicotinamide BDBM50187083 CHEMBL379516
6-Chloro-N-cyclohexyl-1-oxy-nicotinamide CHEMBL60115 BDBM50102227
6-chloro-N-(quinolin-8-yl)nicotinamide CHEMBL1269661 BDBM50330210
BDBM27089 biotinylated NAD+ [3H] Nicotinamide adenine dinucleotide [3H]NAD+
BDBM50219912 CHEMBL236392 2-(4-(2-(benzylamino)ethyl)phenoxy)nicotinamide
BDBM50219915 6-(4-(2-(phenethylamino)ethyl)phenoxy)nicotinamide CHEMBL236168
BDBM50219917 CHEMBL236170 6-(4-(3-(benzylamino)propyl)phenoxy)nicotinamide
BDBM50279877 CHEMBL67352 US9409868, 3 N-Pyridin-4-yl-nicotinamide
BDBM50293648 CHEMBL540426 6-(phenylethynyl)-N-(thiophen-3-ylmethyl)nicotinamide
BDBM50297398 CHEMBL563216 N-[3,3-Bis-(4-fluorophenyl)-propyl]-nicotinamide
BDBM50307188 6-Chloro-N-(2-morpholinoethyl)nicotinamide CHEMBL596768 cid_1228702
BDBM50329208 CHEMBL1269991 5-(4-chlorophenyl)-N-(2-morpholinobenzyl)nicotinamide
BDBM50329210 CHEMBL1269883 N-(2-chlorobenzyl)-5-(4-chlorophenyl)nicotinamide
BDBM50337958 CHEMBL1684242 N-cyclobutyl-6-((3-fluorophenyl)ethynyl)nicotinamide
CHEMBL1086703 BDBM50317397 5-(Aminosulfonyl)-N-ethyl-2-(phenylthio)nicotinamide
CHEMBL1269662 5-bromo-N-(quinolin-8-yl)nicotinamide BDBM50330212
CHEMBL1269716 5-bromo-N-(quinolin-3-yl)nicotinamide BDBM50330221
CHEMBL1271309 5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinamide BDBM50329202
CHEMBL1779845 N-cyclopentyl-6-(pyridin-2-ylethynyl)nicotinamide BDBM50344413
CHEMBL1779846 N-cyclopentyl-6-(pyridin-3-ylethynyl)nicotinamide BDBM50344414
CHEMBL209729 BDBM50187085 6-(4-methoxybenzylamino)-N-(2-aminophenyl)nicotinamide
CHEMBL248820 2-(4-fluorophenylamino)-N-(4-phenoxyphenyl)nicotinamide BDBM50222522
CHEMBL551893 BDBM50293645 N-(4-methylcyclohexyl)-6-(2-phenylethynyl)nicotinamide
CHEMBL551894 BDBM50293646 N-(furan-2-ylmethyl)-6-(phenylethynyl)nicotinamide
CHEMBL565628 N-(3,3-diphenylpropyl)-6-(2,2,2-trifluoroethoxy)nicotinamide BDBM50302473
CHEMBL565841 N-(4-chlorobenzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide BDBM50302471
CHEMBL572206 N-(2-chlorobenzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide BDBM50302472
N-(2,4-dichlorobenzyl)-6-(2,2,2-trifluoroethoxy)nicotinamide BDBM50302474 CHEMBL572205
N-(3,5-dimethylphenyl)-5-(4-fluorophenyl)nicotinamide CHEMBL1271415 BDBM50329214
N-Benzhydryl-6-chloro-1-oxy-nicotinamide BDBM50102228 CHEMBL60578
beta-nicotinamide adenine dinucleotide phosphate, oxidized form NADP+ BDBM11939
2,6-Bis-(3-carbamimidoyl-phenoxy)-N-methyl-nicotinamide BDBM50077188 CHEMBL296530
5-Chloro-6-hydroxy-N-(2-morpholinoethyl)nicotinamide BDBM50307192 CHEMBL599390
5-Chloro-6-hydroxy-N-(3-morpholinopropyl)nicotinamide BDBM50307205 CHEMBL597963
5-Chloro-6-hydroxy-N-(4-methoxyphenyl)nicotinamide BDBM50334331 CHEMBL1642994
6-(2-benzyl-1,2,3,4-tetrahydroisoquinolin-7-yloxy)nicotinamide BDBM50226253 CHEMBL398089
BDBM50077193 2,6-Bis-(3-carbamimidoyl-phenoxy)-N-carbamoylmethyl-nicotinamide CHEMBL49358
BDBM50222502 N-(2-phenoxyphenyl)-2-(pyridin-4-ylmethylamino)nicotinamide CHEMBL249606
BDBM50222509 N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)nicotinamide CHEMBL250228
BDBM50222516 N-(4-butylphenyl)-2-(pyridin-4-ylmethylamino)nicotinamide CHEMBL400140
BDBM50226246 6-(2-phenethyl-1,2,3,4-tetrahydroisoquinolin-7-yloxy)nicotinamide CHEMBL237072
BDBM50226251 CHEMBL397148 6-(2-phenethyl-1,2,3,4-tetrahydroisoquinolin-6-yloxy)nicotinamide
BDBM50288959 CHEMBL421819 N-((R)-1-Mercaptomethyl-2-phenyl-ethyl)-nicotinamide
BDBM50302464 N-(2-(trifluoromethoxy)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide CHEMBL567110
BDBM50326332 CHEMBL1243054 2-Amino-N-(5-chloro-2-phenoxyphenyl)nicotinamide
BDBM50329215 N-(3,5-dimethylphenyl)-5-(4-(trifluoromethoxy)phenyl)nicotinamide CHEMBL1271206
CHEMBL1098817 5-(Aminosulfonyl)-N-(2-methoxyethyl)-2-(phenylthio)-nicotinamide BDBM50317399
CHEMBL1270098 5-(4-chlorophenyl)-N-(pyridin-3-ylmethyl)nicotinamide BDBM50329225
CHEMBL235155 BDBM50226260 6-(2-benzyl-1,2,3,4-tetrahydroisoquinolin-6-yloxy)nicotinamide
CHEMBL236169 6-(4-(2-(3-phenylpropylamino)ethyl)phenoxy)nicotinamide BDBM50219911
CHEMBL238305 BDBM50219933 N-isopropyl-6-(4-((phenethylamino)methyl)phenoxy)nicotinamide
CHEMBL248781 N-(3,4-dichlorophenyl)-2-(pyridin-4-ylmethylamino)nicotinamide BDBM50222513
CHEMBL248980 N-(3-ethylphenyl)-2-(pyridin-4-ylmethylamino)nicotinamide BDBM50222520
CHEMBL250482 N-(4-cyclohexylphenyl)-2-(pyridin-4-ylmethylamino)nicotinamide BDBM50222500
CHEMBL396885 N-(4-(2-morpholino-2-oxoethoxy)phenyl)nicotinamide BDBM50228118
CHEMBL401153 BDBM50222499 N-(3-chlorophenyl)-2-(pyridin-4-ylmethylamino)nicotinamide
CHEMBL566658 BDBM50302467 N-(4-(methylsulfonyl)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide
CHEMBL597762 2-Chloro-6-methyl-N-(3-morpholinopropyl)nicotinamide BDBM50307203
CHEMBL599389 BDBM50307190 2-Chloro-6-methyl-N-(2-morpholinoethyl)nicotinamide
N-((1r,4r)-4-aminocyclohexyl)nicotinamide US10266526, Compound 143 BDBM378015
N-(2-(methylsulfonyl)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide BDBM50302466 CHEMBL566047
N-(3-phenoxyphenyl)-2-(pyridin-4-ylmethylamino)nicotinamide BDBM50222510 CHEMBL249194
N-ethyl-6-(4-((phenethylamino)methyl)phenoxy)nicotinamide BDBM50219930 CHEMBL238283
N-methyl-6-(4-((phenethylamino)methyl)phenoxy)nicotinamide BDBM50219922 CHEMBL396392
pyridine-3-carboxamide BDBM27507 nicotinamide niacinamide 3-Pyridinecarboxamide NAM CHEMBL1140
SMR000514382 N-(2,6-dimethylphenyl)pyridine-3-carboxamide BDBM64053 N-(2,6-dimethylphenyl)-3-pyridinecarboxamide N-(2,6-dimethylphenyl)nicotinamide cid_767628 MLS001204778 N-(2,6-Dimethyl-phenyl)-nicotinamide
2,6-Bis-(3-carbamimidoyl-phenoxy)-N,N-dimethyl-nicotinamide CHEMBL52479 BDBM50077169
2-(2,4-Dimethoxy-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamide CHEMBL323189 BDBM50056056
5-(Aminosulfonyl)-N-ethyl-2-[(3-fluorophenyl)thio]nicotinamide CHEMBL1098349 BDBM50317404
5-bromo-2-hydroxy-N-(quinolin-8-yl)nicotinamide BDBM50330208 CHEMBL1271667
6-(2-(3-phenylpropyl)-1,2,3,4-tetrahydroisoquinolin-6-yloxy)nicotinamide CHEMBL237071 BDBM50226259
6-Chloro-N-(4-fluoro-benzyl)-1-oxy-nicotinamide BDBM50102214 CHEMBL59734
6-Chloro-N-(4-imidazol-1-yl-butyl)-nicotinamide BDBM50024411 CHEMBL8957
6-Chloro-N-(4-iodo-phenyl)-1-oxy-nicotinamide CHEMBL58561 BDBM50102224
6-Chloro-N-(4-methoxy-phenyl)-1-oxy-nicotinamide CHEMBL291368 BDBM50102223
BDBM50024416 CHEMBL268645 6-Chloro-N-(5-imidazol-1-yl-pentyl)-nicotinamide
BDBM50024425 CHEMBL8976 6-Chloro-N-(3-imidazol-1-yl-butyl)-nicotinamide
BDBM50052687 N-[5-(3-Cyclohexyl-propionylamino)-2-methyl-phenyl]-nicotinamide CHEMBL114705
BDBM50056043 CHEMBL110960 2-(2,4-Diethoxy-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamide
BDBM50056052 2-(2,6-Dimethoxy-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamide CHEMBL111282
BDBM50102221 CHEMBL60066 6-Chloro-N-(4-fluoro-phenyl)-1-oxy-nicotinamide
BDBM50102230 CHEMBL62108 6-Cyclopentanesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicotinamide
BDBM50220229 N-(2-aminophenyl)-6-(3,3-dimethylpiperazin-1-yl)nicotinamide CHEMBL392644
BDBM50222496 CHEMBL249611 2-(1H-indazol-6-ylamino)-N-(4-phenoxyphenyl)nicotinamide
BDBM50222517 2-(pyridin-4-ylmethylamino)-N-(4-(trifluoromethoxy)phenyl)nicotinamide CHEMBL248978
BDBM50222815 5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinamide CHEMBL401390
BDBM50232034 CHEMBL256440 N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
BDBM50258375 CHEMBL493573 5-(2-methoxyphenyl)-N-(6-methylpyridin-2-yl)nicotinamide
BDBM50302463 CHEMBL567314 N-(2-chloro-4-cyanobenzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide
BDBM50330209 2-hydroxy-5-methyl-N-(quinolin-8-yl)nicotinamide CHEMBL1271668
CHEMBL1271781 BDBM50330219 2-bromo-5-chloro-N-(quinolin-3-yl)nicotinamide
CHEMBL1271782 2-chloro-5-methyl-N-(quinolin-3-yl)nicotinamide BDBM50330220
CHEMBL1271837 BDBM50330223 5-chloro-2,6-dihydroxy-N-(quinolin-3-yl)nicotinamide
CHEMBL1290247 BDBM50331085 N-(3-(2-(4-bromophenylamino)-2-oxoethoxy)phenyl)nicotinamide
CHEMBL249179 2-(pyridin-4-ylmethylamino)-N-(4-(trifluoromethyl)phenyl)nicotinamide BDBM50222512
CHEMBL292767 6-Chloro-N-(2-hydroxy-phenyl)-1-oxy-nicotinamide BDBM50102215
CHEMBL294095 6-Ethanesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicotinamide BDBM50102216
CHEMBL301424 6-Benzenesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicotinamide BDBM50102229
CHEMBL507803 BDBM50244582 N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide
CHEMBL515756 BDBM50249543 6-((1R,2S)-2-aminocyclohexylamino)-2-(m-tolylamino)nicotinamide
CHEMBL61835 N-(4-Fluoro-phenyl)-6-methanesulfonyl-1-oxy-nicotinamide BDBM50102219
N-(4-Fluoro-phenyl)-1-oxy-6-phenylmethanesulfonyl-nicotinamide BDBM50102226 CHEMBL58619
N-(4-chloro-3-(pyridin-2-yl)phenyl)nicotinamide BDBM50302131 CHEMBL570021
N-(pyridin-2-yl)-6-(tributylstannyl)nicotinamide US9718828, Example, 1 BDBM267471
N-Pyridin-4-yl-2-(2,4,5-trimethoxy-phenylmethanesulfinyl)-nicotinamide BDBM50056048 CHEMBL432440
N-Pyridin-4-yl-2-(2,4,6-trimethoxy-phenylmethanesulfinyl)-nicotinamide BDBM50056042 CHEMBL108285
N-[1-(1-Ethylaminooxalyl-propylcarbamoyl)-3-methyl-butyl]-nicotinamide BDBM50053810 CHEMBL130722
N-[4,4-Bis-(4-fluorophenyl)-propyl]-6-hydroxy-nicotinamide CHEMBL563417 BDBM50297402
N-[5-(4-Cyclohexyl-butyryl)-2-methyl-phenyl]-nicotinamide CHEMBL114199 BDBM50052691
6-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-nicotinamide 6-fluoro-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)nicotinamide BDBM50172861 CHEMBL198993
2-Amino-N-(2-aminoethyl)-5-(thiophen-3-yl)nicotinamide BDBM50309209 CHEMBL610226
5-(4-chlorophenyl)-N-((2-chloropyridin-3-yl)methyl)nicotinamide BDBM50329207 CHEMBL1270100
5-(4-chlorophenyl)-N-((2-methylpyridin-3-yl)methyl)nicotinamide CHEMBL1270099 BDBM50329226
5-(Aminosulfonyl)-2-[(3,4-difluorophenyl)thio]-N-(4-methoxybenzyl)nicotinamide CHEMBL1095203 BDBM50317405
5-(Aminosulfonyl)-N-(3-methoxypropyl)-2-[(2,3,5,6-tetrafluorophenyl)thio]nicotinamide BDBM50317407 CHEMBL1099137
5-(Aminosulfonyl)-N-[2-(dimethylamino)ethyl]-2-(phenyl-thio)nicotinamide CHEMBL1098816 BDBM50317398
6-(4-fluorophenyl)-2-methyl-N-(quinolin-7-yl)nicotinamide CHEMBL477204 BDBM50263425
BDBM50056050 2-(Di-p-tolyl-methanesulfinyl)-N-pyridin-4-yl-nicotinamide CHEMBL111351
BDBM50104045 N-[3-Benzoyl-4-(2-p-tolyl-acetylamino)-phenyl]-nicotinamide CHEMBL106252
BDBM50185115 CHEMBL209204 N-(3-carbamoyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)nicotinamide
BDBM50191722 6-(3-methylpyridin-2-yl)-N-(4-(trifluoromethyl)phenyl)nicotinamide CHEMBL385241
BDBM50222518 CHEMBL403349 2-(benzo[b]thiophen-3-ylamino)-N-(4-phenoxyphenyl)nicotinamide
BDBM50269083 6-[4-(4-Benzylphthalazin-1-yl)piperazin-1-yl]nicotinamide CHEMBL495875
BDBM50297399 CHEMBL564145 N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phenyl)-propyl]-nicotinamide
BDBM50302477 CHEMBL566038 N-(3,3-diphenylpropyl)-6-(2-(pyrrolidin-1-yl)ethyl)nicotinamide
BDBM50317408 5-(Aminosulfonyl)-2-[(3,4-difluorophenyl)thio]-N-(3-methoxypropyl)nicotinamide CHEMBL1086834
BDBM50329204 5-(4-chlorophenyl)-N-((2-morpholinopyridin-3-yl)methyl)nicotinamide CHEMBL1270302
CHEMBL1269990 BDBM50329209 5-(4-chlorophenyl)-N-(2-(piperidin-1-yl)benzyl)nicotinamide
CHEMBL1270207 BDBM50329206 5-(4-chlorophenyl)-N-((2-ethoxypyridin-3-yl)methyl)nicotinamide
CHEMBL236892 (S)-N-(2-aminophenyl)-6-(3-methylpiperazin-1-yl)nicotinamide BDBM50220233
CHEMBL237324 (S)-N-(2-aminophenyl)-6-(3-isopropylpiperazin-1-yl)nicotinamide BDBM50220243
CHEMBL237325 (S)-N-(2-aminophenyl)-6-(3-benzylpiperazin-1-yl)nicotinamide BDBM50220242
CHEMBL249599 BDBM50222514 N-(3-(1-hydroxyethyl)phenyl)-2-(pyridin-4-ylmethylamino)nicotinamide
CHEMBL250471 5-bromo-N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)nicotinamide BDBM50222523
CHEMBL393263 BDBM50204172 5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)-2-(3,4-difluorophenoxy)nicotinamide
CHEMBL400512 BDBM50222498 N-(3,5-bis(trifluoromethyl)phenyl)-2-(pyridin-4-ylmethylamino)nicotinamide
CHEMBL472906 N-((3S,5S)-5-(Hydroxycarbamoyl)-1-acetylpyrrolidin-3-yl)nicotinamide BDBM50247270
N-(2,4-dichlorobenzyl)-6-(2-(pyrrolidin-1-yl)ethyl)nicotinamide BDBM50302478 CHEMBL568342
N-(2-chloro-4-(methylsulfonyl)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide BDBM50302469 CHEMBL568544
N-(2-methyl-5-((3-(trifluoromethyl)phenyl)carbamoyl)phenyl)nicotinamide BDBM50244630 CHEMBL454105
N-(3-Aminopropyl)-5-(aminosulfonyl)-2-[(2,3,5,6-tetrafluorophenyl)thio]nicotinamide CHEMBL1099151 BDBM50317410
N-(4-bromo-2-(trifluoromethoxy)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide CHEMBL566648 BDBM50302462
N-(4-chloro-2-(methylsulfonyl)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide BDBM50302468 CHEMBL585949
N-(4-chlorophenyl)-6-methyl-2-(pyridin-4-ylmethylamino)nicotinamide CHEMBL250470 BDBM50222521
N-(4-tert-Butyl-phenyl)-6-chloro-1-oxy-nicotinamide CHEMBL293139 BDBM50102220
N-[4-(3,4-Dihydro-2H-quinoline-1-carbonyl)-phenyl]-nicotinamide BDBM50052931 CHEMBL118933
N-biphenyl-3-yl-2-[(pyridin-4-ylmethyl)-amino]-nicotinamide BDBM50222507 CHEMBL399546
N-biphenyl-4-yl-2-[(pyridin-4-ylmethyl)-amino]-nicotinamide CHEMBL248976 BDBM50222503
US10266526, Compound 123 6-amino-N-((1r,4r)-4-aminocyclohexyl)nicotinamide BDBM377995
US10266526, Compound 142 N-((1r,4r)-4-(3-aminopropanamido)cyclohexyl)nicotinamide BDBM378014
US10266526, Compound 289 4-amino-N-((1r,4r)-4-aminocyclohexyl)nicotinamide BDBM378159
US11241428, Example 2 BDBM535853 N-(3-amino-6-phenylpyridin-2-yl)nicotinamide
US11452717, Compound TableB-3.29 BDBM572852 6-(3-Pyridin-4-ylmethyl-ureido)-nicotinamide
(R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)nicotinamide BDBM50176377 CHEMBL204449
2-(5-Bromo-2,4-dimethoxy-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamide BDBM50056047 CHEMBL109629
2-(benzo[d][1,3]dioxol-5-ylmethylamino)-N-(4-phenoxyphenyl)nicotinamide BDBM50222508 CHEMBL249806
2-Amino-N-(2-(dimethylamino)ethyl)-5-(thiophen-3-yl)nicotinamide CHEMBL599582 BDBM50309185
2-Benzyloxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-nicotinamide BDBM50160121 CHEMBL179779
2-Butoxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-nicotinamide BDBM50160105 CHEMBL181164
5-(4-Chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-hexyl-nicotinamide BDBM50160102 CHEMBL360711
5-(4-Chloro-phenyl)-N-cyclohexyl-6-(2,4-dichloro-phenyl)-nicotinamide CHEMBL362650 BDBM50160141
6-(5,6-Dimethoxy-benzoimidazol-1-yl)-2-phenylamino-nicotinamide US20240366581, Example 2 BDBM702924
BDBM377833 US10266526, Compound 3 N-(1-((4-acetamidophenyl)sulfonyl)piperidin-4-yl)nicotinamide
BDBM50034305 CHEMBL24113 N-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-nicotinamide
BDBM50056041 CHEMBL108536 2-(2,4-Dimethoxy-6-methyl-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamide
BDBM50056044 2-(2,4-Dimethoxy-3-methyl-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamide CHEMBL322809
BDBM50178828 CHEMBL380625 N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)nicotinamide
BDBM50180565 CHEMBL202771 4-(4-bromo-2-chlorophenylamino)-5,6-dichloro-N-(2-hydroxyethoxy)nicotinamide
BDBM50191754 CHEMBL213817 N-(3-diethylaminomethyl-quinolin-8-ylmethyl)-6-(4-fluoro-phenyl)-nicotinamide
BDBM50191760 CHEMBL216038 N-(3-dimethylaminomethyl-quinolin-8-ylmethyl)-6-(4-fluoro-phenyl)-nicotinamide
BDBM50202127 N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)nicotinamide CHEMBL247746
BDBM50226256 6-(4-(2-(3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenoxy)nicotinamide CHEMBL237295
BDBM50252750 CHEMBL493879 5-bromo-N-{[1-(3,3-dimethylbutyl)piperidin-4-yl]methyl}nicotinamide
BDBM50254611 CHEMBL519614 N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-yl)nicotinamide
BDBM50275709 N-(2-aminophenyl)-6-(spiro[indoline-3,4'-piperidine]-1'-yl)nicotinamide CHEMBL520050
BDBM50310634 CHEMBL1078027 N-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenyl)nicotinamide
BDBM50314071 VX-702 CHEMBL1090090 2-(2,4-difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide
BDBM50317406 CHEMBL1095204 5-(Aminosulfonyl)-N-(3-methoxypropyl)-2-[(3-fluorophe-nyl)thio]nicotinamide
CHEMBL108610 BDBM50056045 2-(2-Ethoxy-4-methoxy-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamide
CHEMBL1098839 BDBM50317403 5-(Aminosulfonyl)-N-(pyridin-2-ylmethyl)-2-[(2,3,5,6-tetrafluorophenyl)thio]nicotinamide
CHEMBL218555 BDBM50203861 N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-nicotinamide
CHEMBL250684 BDBM50222501 N-(4-chloro-3-(trifluoromethyl)phenyl)-2-(pyridin-4-ylmethylamino)nicotinamide
CHEMBL26447 N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-nicotinamide BDBM50034283
CHEMBL322031 BDBM50008636 (R)-N-[1-Dipentylcarbamoyl-2-(1H-indol-3-yl)-ethyl]-nicotinamide
CHEMBL365694 BDBM50170550 4-(4-Chloro-phenoxy)-N-(4-hydroxycarbamoylmethyl-thiazol-2-yl)-nicotinamide
CHEMBL499776 BDBM50275768 N-(2-aminophenyl)-6-(2,8-diazaspiro[4.5]decan-8-yl)nicotinamide
CHEMBL560740 BDBM50297412 N-[3,3-Bis-(4-fluorophenyl)-propyl]-6-(2,2,2-trifluoro-ethoxy)-nicotinamide
CHEMBL589378 BDBM50304939 N-phenethyl-6-(4-(2-(trifluoromethyl)benzoyl)piperazin-1-yl)nicotinamide
CHEMBL79004 BDBM50130248 PS-1145 N-(6-Chloro-9H-beta-carbolin-8-yl)-nicotinamide
N,N-Diethyl-6-(spiro[chromene-2,4'-piperidine]-4-yl)nicotinamide BDBM50297335 CHEMBL561138
N-((4'-(methylsulfonyl)biphenyl-4-yl)methyl)-6-(3,3,3-trifluoropropoxy)nicotinamide CHEMBL567703 BDBM50302461
N-(2-aminophenyl)-6-((2R,5S)-2,5-dimethylpiperazin-1-yl)nicotinamide BDBM50220250 CHEMBL237326
N-(2-aminophenyl)-6-((3S,5R)-3,5-dimethylpiperazin-1-yl)nicotinamide BDBM50220245 CHEMBL538906
N-(2-chloro-4-(N-methylsulfamoyl)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide BDBM50302465 CHEMBL566048
N-(3-(5-chlorobenzo[d]oxazol-2-yl)-4-hydroxyphenyl)nicotinamide BDBM50178734 CHEMBL425205
N-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethyl)pyridin-2-yl)nicotinamide BDBM50191741 CHEMBL215482
N-(4-Fluoro-phenyl)-1-oxy-6-(propane-2-sulfonyl)-nicotinamide BDBM50102218 CHEMBL61655
N-(4-chloro-3-(phenylcarbamoyl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302118 CHEMBL571352
N-[4-(3-Dimethylamino-pyrrolidin-1-yl)-phenyl]-6-phenyl-nicotinamide BDBM50170412 CHEMBL179345
N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-nicotinamide CHEMBL23912 BDBM50034307
US20250129067, Compound Motesanib N-(3,3-dimethylindolin-6-yl)-2-(4-pyridylmethylamino)nicotinamide BDBM31101
BDBM38284 N-(4-piperidin-1-ylphenyl)pyridine-3-carboxamide MLS000074324 cid_650959 N-(4-piperidinophenyl)nicotinamide N-(4-Piperidin-1-yl-phenyl)-nicotinamide SMR000012469 N-[4-(1-piperidinyl)phenyl]-3-pyridinecarboxamide
cid_901941 BDBM75495 2-[(4-methylphenyl)amino]pyridine-3-carboxamide 2-(4-methylanilino)pyridine-3-carboxamide 2-(4-methylanilino)-3-pyridinecarboxamide 2-(4-toluidino)nicotinamide SMR000226873 2-(p-toluidino)nicotinamide MLS000700317
2-(phenethylamino)-N-phenyl-nicotinamide SMR000200612 BDBM78163 MLS000581683 N-phenyl-2-[(2-phenylethyl)amino]nicotinamide N-phenyl-2-(2-phenylethylamino)pyridine-3-carboxamide cid_714469 N-phenyl-2-(2-phenylethylamino)-3-pyridinecarboxamide
5-(4-cyanophenyl)-N-[3-methoxy-5-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]nicotinamide BDBM84399 5-(4-cyanophenyl)-N-[3-methoxy-5-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]nicotinamide;2,2,2-trifluoroacetic acid cid_16745786
N-((3S,5S)-1-(3-(3,4-dimethoxyphenyl)acryloyl)-5-(hydroxycarbamoyl)pyrrolidin-3-yl)nicotinamide N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-(hydroxycarbamoyl)pyrrolidin-3-yl)nicotinamide CHEMBL472915 BDBM50247539
2-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-N-(4-chlorophenyl)nicotinamide BDBM50317748 CHEMBL1097141
2-(piperidin-1-yl)-N-(3-sulfamoylphenyl)-6-(trifluoromethoxy)nicotinamide US12344595, Example 84 BDBM754168
2-Amino-N-(3-amino-3-oxopropyl)-5-(thiophen-3-yl)nicotinamide CHEMBL599581 BDBM50309187
4-amino-N-((1r,4r)-4-(3-aminopropanamido)cyclohexyl)nicotinamide US10266526, Compound 288 BDBM378158
5-cyclopentyl-2- (piperidin-1-yl)-N-(3- sulfamoylphenyl)- nicotinamide BDBM754238 US12344595, Example 154
5-isobutyl-2-(piperidin-1-yl)-N-(3-sulfamoylphenyl)nicotinamide US12344595, Example 153 BDBM754237
6-(2,5-diaza-bicyclo[2.2.2]octan-2-yl)-N-(2-aminophenyl)nicotinamide BDBM50220251 CHEMBL237558
6-(2-hexyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide CHEMBL237716 BDBM50226249
6-(2-phenethyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide BDBM50226261 CHEMBL237073
6-(3-benzyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)nicotinamide BDBM50226265 CHEMBL237293
6-amino-N-((1r,4r)-4-(3-aminopropanamido)cyclohexyl)nicotinamide US10266526, Compound 388 BDBM378257
BDBM50097627 2-(3-Carbamimidoyl-phenyl)-N-(2'-sulfamoyl-biphenyl-4-yl)-nicotinamide; TFA CHEMBL351755
BDBM50183324 CHEMBL382221 N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]nicotinamide
BDBM50220252 CHEMBL237328 N-(2-aminophenyl)-6-(3,3-dimethyl-4-(phenylsulfonyl)piperazin-1-yl)nicotinamide
BDBM50222506 N-(4-(4-methylpiperazin-1-yl)phenyl)-2-(pyridin-4-ylmethylamino)nicotinamide CHEMBL400102
BDBM50226244 6-(2-isopentyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide CHEMBL237718
BDBM50226250 6-(2-pentyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide CHEMBL237506
BDBM50226254 CHEMBL237505 6-(2-butyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide
BDBM50226263 6-(3-phenethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)nicotinamide CHEMBL237294
BDBM50231054 CHEMBL398909 N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-6-(trifluoromethyl)nicotinamide
BDBM50317409 CHEMBL1095531 5-(Aminosulfonyl)-N-(2-pyridin-2-ylethyl)-2-[(2,3,5,6-tetrafluorophenyl)thio]nicotinamide
BDBM50322984 N-(1-(3,5-diethoxy-4-fluorobenzyl)piperidin-4-yl)-6-(isopropylamino)nicotinamide CHEMBL1210143
BDBM50322993 CHEMBL1210029 6-amino-N-(1-(3-ethoxy-4-methylbenzyl)piperidin-4-yl)nicotinamide
CHEMBL102331 BDBM50119703 N-{(S)-1-[3-(4-Acetyl-phenoxy)-propyl]-pyrrolidin-3-yl}-nicotinamide
CHEMBL1097869 4-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide BDBM50317760
CHEMBL1099152 5-(Aminosulfonyl)-N-[2-(4-methoxyphenyl)ethyl]-2-[(2,3,5,6-tetrafluorophenyl)thio]nicotinamide BDBM50317411
CHEMBL1270208 5-(4-chlorophenyl)-N-((2-(2,2,2-trifluoroethoxy)pyridin-3-yl)methyl)nicotinamide BDBM50329203
CHEMBL237970 6-(2,5-diaza-bicyclo[2.2.1]heptan-2-yl)-N-(2-aminophenyl)nicotinamide BDBM50220269
N-(1-(1-(L-alanyl)piperidin-4-yl)ethyl)nicotinamide US10266526, Compound 141 BDBM378013
N-(1-(3,5-diethoxy-4-fluorobenzyl)piperidin-4-yl)-6-(methylamino)nicotinamide BDBM50322977 CHEMBL1210268
N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)nicotinamide CHEMBL516312 BDBM50273541
N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-nicotinamide; hydrochloride BDBM50069473 CHEMBL538070
US11130748, Example 33 BDBM520220 N-((1-Cyanopyrrolidin-3- yl)methyl)-5-(4- fluorophenyl)nicotinamide
US12344595, Example 164 BDBM754248 2-(azepan-1-yl)-5-(perfluoroethyl)-N-(3-sulfamoylphenyl)nicotinamide
US12344595, Example 86 BDBM754170 2-(azepan-1-yl)-N-(3-sulfamoylphenyl)-5-(trimethylsilyl)nicotinamide
US9951056, Example 62 BDBM389682 2-(4-phenoxyphenyl)-6-(4-(vinylsulfonyl)piperazin-1-yl)nicotinamide
cid_744674 SMR000121062 4,6-dimethyl-2-(1-naphthylamino)nicotinamide MLS000528487 4,6-dimethyl-2-(naphthalen-1-ylamino)pyridine-3-carboxamide 4,6-dimethyl-2-(1-naphthalenylamino)-3-pyridinecarboxamide BDBM34670 4,6-Dimethyl-2-(naphthalen-1-ylamino)-nicotinamide
2-(3-(4-(aminoquinazolin- 6-yl)benzylamino)-N-(3,4- difluorobenzyl)nicotinamide BDBM281959 US10030016, Example 6.1
2-(4,4-difluoroazepan-1-yl)-5-(difluoromethoxy)-N-(3-sulfamoylphenyl)nicotinamide US12344595, Example 172 BDBM754256
2-(piperidin-1-yl)-N-(3-sulfamoylphenyl)-5-(p-tolyl)nicotinamide US12344595, Example 27 BDBM754111
2-Butoxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-methyl-nicotinamide BDBM50160111 CHEMBL182948
2-Chloro-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-hexyl-nicotinamide CHEMBL178243 BDBM50160144
2-methyl-N-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethyl)pyridin-2-yl)nicotinamide CHEMBL215650 BDBM50191693
4-cyclopropyl-6-(2,5-dichlorophenylamino)-N-((tetrahydro-2H-pyran-4-yl)methyl)nicotinamide CHEMBL479628 BDBM50254738
5-(4-chlorophenyl)-N-((2-(piperidin-1-yl)pyridin-3-yl)methyl)nicotinamide CHEMBL1270301 BDBM50329205
5-cyclobutyl-2-(4,4-difluoroazepan-1-yl)-N-(3-sulfamoylphenyl)nicotinamide US12344595, Example 159 BDBM754243
6-(2,4-dichlorophenylamino)-4-isopropyl-N-((tetrahydro-2H-pyran-4-yl)methyl)nicotinamide BDBM50254444 CHEMBL466191
6-(2-(2-morpholinoethyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide BDBM50226267 CHEMBL238363
6-(2-(3,3-dimethylbutyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide BDBM50226264 CHEMBL396637
6-(2-(4,4,4-trifluorobutyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide BDBM50226266 CHEMBL439038
6-(2-(5-methylhexyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide BDBM50226252 CHEMBL237934
6-(4-fluoro-phenyl)-N-(3-morpholin-4-ylmethyl-quinolin-8-ylmethyl)-nicotinamide CHEMBL215131 BDBM50191757
6-(tert-butyl)-2-(piperidin-1-yl)-N-(3-sulfamoylphenyl)nicotinamide US12344595, Example 42 BDBM754126
BDBM282495 2-(4-(6-aminopyridin-3- yl)benzylamino)-N-(4- fluorophenyl)nicotinamide US10030016, Example 375
BDBM360562 N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-5- (trifluoromethyl)nicotinamide US9828369, Example 119
BDBM407100 6-(3-cyanopyrrolo[1,2-b] pyridazin-7- yl)-4-(isopropylamino) nicotinamide US10336762, Compound 39
BDBM50056051 CHEMBL325803 2-[2-(2-Fluoro-ethoxy)-4-methoxy-phenylmethanesulfinyl]-N-pyridin-4-yl-nicotinamide
BDBM50056054 2-[2-(2-Hydroxy-ethoxy)-4-methoxy-phenylmethanesulfinyl]-N-pyridin-4-yl-nicotinamide CHEMBL320710
BDBM50128681 CHEMBL80933 N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-(4-dimethylaminomethyl-phenyl)-vinyl]-nicotinamide
BDBM50160092 5-(4-Chloro-phenyl)-2-cyclohexylmethoxy-6-(2,4-dichloro-phenyl)-N-propyl-nicotinamide CHEMBL180394
BDBM50160117 5-(4-Chloro-phenyl)-2-cyclohexylmethoxy-6-(2,4-dichloro-phenyl)-N-methyl-nicotinamide CHEMBL360723
BDBM50160129 CHEMBL361785 2-Benzyloxy-5-(4-chloro-phenyl)-N-cyclopentyl-6-(2,4-dichloro-phenyl)-nicotinamide
BDBM50171567 N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-2,5-dichloro-nicotinamide CHEMBL194630
BDBM50171582 CHEMBL195511 N-(1-Benzyl-piperidin-4-yl)-5-chloro-2-(4-methoxy-benzylamino)-nicotinamide
BDBM50184127 CHEMBL207443 N-((S)-Phenyl-propylcarbamoyl-methyl)-6-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-nicotinamide
BDBM50220267 CHEMBL237327 N-(2-aminophenyl)-6-(3,3-dimethyl-4-(3-phenylpropanoyl)piperazin-1-yl)nicotinamide
BDBM50226245 6-(2-(4-methylpentyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide CHEMBL396636
BDBM50226257 CHEMBL238364 6-(2-(3-morpholinopropyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide
BDBM50231107 N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-6-(2,2,2-trifluoroethoxy)nicotinamide CHEMBL252178
BDBM50254701 6-(3-bromophenylamino)-4-cyclopropyl-N-((tetrahydro-2H-pyran-4-yl)methyl)nicotinamide CHEMBL480398
BDBM50263384 CHEMBL514691 6-(4-fluorophenyl)-2-methyl-N-(2-methylbenzothiazol-5-yl)nicotinamide SB-782443
BDBM50322983 N-(1-((2,6-diethoxybiphenyl-4-yl)methyl)piperidin-4-yl)-6-(methylamino)nicotinamide CHEMBL1210144
BDBM65498 NICOTINAMIDE 1,N6-ETHENOADENINE DINUCLEOTIDE 1,N6-ETHENO NAD 1,N6-ETHENONICOTINAMIDE ADENINE DINUCLEOTIDE
BDBM754107 2-(azepan-1-yl)-5-methyl- N-(3-sulfamoyl- phenyl)nicotinamide US12344595, Example 23
CHEMBL1210082 rac-6-amino-N-(1-(3-ethoxy-4,5-difluorobenzyl)azepan-4-yl)nicotinamide BDBM50322990
CHEMBL152425 BDBM50122085 N-[1-[8-(3-Amino-propylamino)-octylcarbamoyl]-2-(4-hydroxy-phenyl)-ethyl]-nicotinamide
CHEMBL163848 BDBM50139620 5-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido]-phenoxy}-N-methyl-nicotinamide
CHEMBL175838 BDBM50161237 N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-nicotinamide
CHEMBL178250 N-[4-(3-Dimethylamino-pyrrolidin-1-yl)-phenyl]-6-(4-methoxy-phenyl)-nicotinamide BDBM50170408
CHEMBL180861 BDBM50160124 2-Butoxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-propyl-nicotinamide
CHEMBL182241 BDBM50160110 5-(4-Chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-piperidin-1-yl-nicotinamide
CHEMBL196273 BDBM50171595 5-Chloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-cyclobutylamino-nicotinamide
CHEMBL238156 6-(2-(2-ethylbutyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide BDBM50226262
CHEMBL238157 BDBM50226255 6-(2-(3-cyclohexylpropyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide
CHEMBL248650 5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-furan-2-ylmethyl-nicotinamide BDBM50222826
CHEMBL356498 BDBM50054719 N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-nicotinamide
CHEMBL359500 BDBM50160119 2-Chloro-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-propyl-nicotinamide
CHEMBL360763 BDBM50160137 2-Benzyloxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-ethyl-nicotinamide
CHEMBL385178 N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide BDBM15019 nicotinamide 35
CHEMBL426241 2-Benzyloxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-methyl-nicotinamide BDBM50160127
CHEMBL426601 BDBM50160133 2-Benzyloxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-propyl-nicotinamide
CHEMBL471824 N-(4-aminobiphenyl-3-yl)-6-(2,8-diazaspiro[4.5]decan-8-yl)nicotinamide BDBM50275769
CHEMBL486737 N-(2-aminophenyl)-6-(7-(phenylsulfonyl)-2,7-diazaspiro[4.4]nonan-2-yl)nicotinamide BDBM50275708
CHEMBL488389 BDBM50275684 N-(4-chlorophenethyl)-2-(methylamino)-N-(1,4-dioxaspiro[4.5]decan-8-yl)nicotinamide
CHEMBL49076 BDBM50127783 N-[2-(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-naphthalen-1-yl]-nicotinamide
CHEMBL517646 BDBM50254661 4-cyclopropyl-6-(2,4-dichlorophenylamino)-N-((tetrahydro-2H-pyran-4-yl)methyl)nicotinamide
CHEMBL520381 N-(4-chlorophenethyl)-2-isopropoxy-N-(1,4-dioxaspiro[4.5]decan-8-yl)nicotinamide BDBM50275726
CHEMBL562082 (S)-N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phenyl)-propyl]-6-hydroxy-nicotinamide BDBM50297395
CHEMBL567294 N-(2-chloro-4-(1H-tetrazol-1-yl)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide BDBM50302460
CHEMBL568926 N-(4-chloro-3-(pyridin-4-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302125
CHEMBL570936 N-(4-chloro-3-(quinoxalin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302128
CHEMBL572251 BDBM50302116 N-(4-chloro-3-(indolizin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide
N-((S)-benzylcarbamoyl-phenyl-methyl)-6-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-nicotinamide BDBM50184154 CHEMBL206965
N-(2-Amino-6-furan-2-yl-5-nitro-pyrimidin-4-yl)-nicotinamide CHEMBL551177 BDBM50294517
N-(3,4-difluorobenzyl)-2-(3-(1-oxoisoindolin-4-yl)phenylamino)-nicotinamide BDBM282133 US10030016, Example 17.1
N-(4-(5-methylthiophene-2-carbonyl)thieno[3,2-d]pyrimidin-2-yl)nicotinamide BDBM50310904 CHEMBL1078001
N-(4-chloro-3-(pyrazin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302127 CHEMBL572018
N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302123 CHEMBL571353
N-(4-chloro-3-(pyridin-3-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302124 CHEMBL572256
N-(4-chloro-3-(pyrimidin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302126 CHEMBL568884
N-[4-(1-butyryl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-2-methyl-nicotinamide BDBM50203851 CHEMBL441870
N-quinolin-7-yl-6-phenylnicotinamide CHEMBL213390 BDBM50189987 6-phenyl-N-(quinolin-7-yl)nicotinamide
US10981893, Example 5 BDBM492876 5-benzyl-N-((5-chloro- 1H-indazol-3- yl)methyl)nicotinamide
US12344595, Example 162 2-(4,4-difluoroazepan-1-yl)-5-isopropyl-N-(3-sulfamoylphenyl)nicotinamide BDBM754246
US12344595, Example 39 2-(4,4-difluoroazepan-1-yl)-N-(3-sulfamoylphenyl)-5-(trifluoromethoxy)nicotinamide BDBM754123
US9828369, Example 127 N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-4- (trifluoromethyl)nicotinamide BDBM360570
US9828369, Example 28 BDBM360455 5-bromo-N-((5-(3- methoxyphenyl)isoquinolin-8- yl)methyl)nicotinamide
endo-5-((1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-yloxy)nicotinamide BDBM50325863 CHEMBL1224068
endo-6-((1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-yloxy)nicotinamide CHEMBL1224217 BDBM50325873
SMR000005499 BDBM40798 N-[6-(pentanoylamino)pyridin-3-yl]pyridine-3-carboxamide cid_651707 N-(6-Pentanoylamino-pyridin-3-yl)-nicotinamide MLS000068397 N-[6-(1-oxopentylamino)-3-pyridinyl]-3-pyridinecarboxamide N-[6-(valerylamino)-3-pyridyl]nicotinamide
N-(1-benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-chloro-2-(2-isopropoxyethylamino)nicotinamide BDBM50171583 CHEMBL194583 N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-chloro-2-(2-isopropoxy-ethylamino)-nicotinamide
N-(4-Methoxy-9-oxo-6-phenyl-1,2,8,9-tetrahydro-5,7,9a-triaza-benzo[cd]azulen-8-yl)-nicotinamide BDBM50147630 CHEMBL112996 N-(4-methoxy-9-oxo-6-phenyl-1,2,8,9-tetrahydro-5,7,9a-triazabenzo[cd]azulen-8-yl)nicotinamide
2-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)-5-bromo-N-(2,4-difluorophenyl)nicotinamide BDBM50317758 CHEMBL1098176
2-(azepan-1-yl)-6-chloro-4-methyl-N-(3-sulfamoylphenyl)nicotinamide US12344595, Example 29 BDBM754113
2-(azepan-1-yl)-6-methoxy-5-methyl-N-(3-sulfamoylphenyl)nicotinamide BDBM754239 US12344595, Example 155
5-(N-ethyl-N-(2,2,2-trifluoro-1-(4- fluorophenyl)ethyl)sulfamoyl)nicotinamide US20250115569, Example 51 BDBM732508
5-Chloro-N-(1,4-diethyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide CHEMBL164324 BDBM50123810
5-Chloro-N-(1,4-dimethyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide BDBM50123802 CHEMBL349595
6-((3-(6- (cyclopropylmethoxy)pyridin-3- yl)phenoxy)methyl)-N- (methylsulfonyl)nicotinamide BDBM499370 US11020381, Example 63
BDBM281953 US10030016, Example 5.3 N-(3,4-difluorobenzyl)-2-(3- isopropoxy-5-(quinazolin- 6-yl)benzylamino) nicotinamide
BDBM412444 5-fluoro-4-methyl-N-(5-(1- phenylcyclopropyl)pyrazin-2- yl)nicotinamide US10399967, Compound 74
BDBM492873 N-((5-chloro-1H- indazol-3-yl)methyl)-5- (4- cyanobenzyl) nicotinamide US10981893, Example 2
BDBM499417 US11020381, Example 113 6-((3-(6- (cyclobutylmethoxy)pyridin-3- yl)phenoxy)methyl)-N- (methylsulfonyl)nicotinamide
BDBM50069493 N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-2-methyl-nicotinamide; hydrochloride CHEMBL541600
BDBM50123797 CHEMBL349050 5-Bromo-N-(1,4-diethyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide
BDBM50160093 2-Chloro-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N,N-dimethyl-nicotinamide CHEMBL180077
BDBM50171568 CHEMBL372245 5-Chloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-(cyclopropylmethyl-amino)-nicotinamide
BDBM50186062 1-hydroxy-N,N-diisobutyl-6-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-nicotinamide CHEMBL211217
BDBM50247520 N-((3S,5S)-5-(Hydroxycarbamoyl)-1-(3-(3,4-dimethoxyphenyl)propanoyl)pyrrolidin-3-yl)nicotinamide CHEMBL514309
BDBM50254700 CHEMBL465470 4-tert-butyl-6-(2,4-dichlorophenylamino)-N-((tetrahydro-2H-pyran-4-yl)methyl)nicotinamide
BDBM50275710 CHEMBL486738 N-(2-aminophenyl)-6-(2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-yl)nicotinamide
BDBM50297414 CHEMBL556234 N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phenyl)-propyl]-6-(2,2,2-trifluoro-ethoxy)-nicotinamide
BDBM50324480 CHEMBL1215516 N-(1-Amino-1-oxo-3-phenylpropan-2-yl)-6-(thiophen-2-yl)nicotinamide
BDBM50330098 N-(4-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)nicotinamide CHEMBL1271497
BDBM754240 2-(azepan-1-yl)-5-bromo-6-methoxy-N-(3-sulfamoylphenyl)nicotinamide US12344595, Example 156
BDBM754252 2-(azepan-1-yl)-6-methyl-N-(3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide US12344595, Example 168
BDBM754253 2-(azepan-1-yl)-6-methoxy-N-(3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide US12344595, Example 169
CHEMBL1643870 BDBM50334428 N-((3S,5R)-5-((N-hydroxyformamido)methyl)-2-methyl-4-oxononan-3-yl)nicotinamide
CHEMBL175381 BDBM50142098 N-(5-Chloro-pyridin-2-yl)-2-[(2'-sulfamoyl-biphenyl-4-carbonyl)-amino]-nicotinamide
CHEMBL183292 BDBM50157974 N-(13-Benzenesulfonylamino-tricyclo[8.2.1.0*3,8*]trideca-3(8),4,6-trien-5-yl)-nicotinamide
CHEMBL238211 N-(2-aminophenyl)-6-(hexahydro-1H-pyrido[1,2-a]pyrazin-2(6H)-yl)nicotinamide BDBM50220249
CHEMBL361152 2-Benzyloxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N,N-dimethyl-nicotinamide BDBM50160098
CHEMBL413799 BDBM50220234 N-(2-aminophenyl)-6-(5-benzyl-2,5-diaza-bicyclo[2.2.1]heptan-2-yl)nicotinamide
CHEMBL454168 BDBM50247709 4-chloro-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)nicotinamide
CHEMBL514501 N-(4-chloro-2-(5-chloropyridin-2-ylcarbamoyl)phenyl)-6-(N,N-dimethylcarbamimidoyl)nicotinamide BDBM50249390
CHEMBL520413 4-cyclopropyl-N-((tetrahydro-2H-pyran-4-yl)methyl)-6-(3-(trifluoromethoxy)phenylamino)nicotinamide BDBM50254702
CHEMBL540332 N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-6-methyl-nicotinamide; hydrochloride BDBM50069477
CHEMBL541400 BDBM50325991 CHEMBL1242100 CHEMBL1190711 2-(7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-ylamino)nicotinamide hydrochloride
CHEMBL562136 N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-6-(4-fluorophenyl)nicotinamide BDBM50297071
CHEMBL569818 BDBM50302115 N-(4-chloro-3-(2H-indazol-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide
CHEMBL570958 BDBM50301331 5-chloro-6-(1'-(4-chlorobenzyl)-4,4'-bipiperidin-1-yl)-N-(3,4-dichlorobenzyl)nicotinamide
CHEMBL583032 N-(4-chloro-3-(1H-indol-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302110
CHEMBL583451 N-(4-chloro-3-(1H-pyrazol-3-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302121
N-((1S,2S,4R)-1-Benzyl-2-hydroxy-6-methyl-4-methylcarbamoyl-heptyl)-nicotinamide CHEMBL69645 BDBM50144385
N-(3-(benzo[d]thiazol-2-yl)-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302113 CHEMBL572005
N-(4-chloro-3-(1H-pyrazol-1-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide CHEMBL585532 BDBM50302120
N-(5-Chloro-pyridin-2-yl)-4-[(2'-sulfamoyl-biphenyl-4-carbonyl)-amino]-nicotinamide CHEMBL368862 BDBM50142114
N-[(S)-(cyclopropylmethyl-carbamoyl)-phenyl-methyl]-6-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-nicotinamide CHEMBL378263 BDBM50184168
US10030016, Example 5.4 BDBM281954 N-(3,4-difluorobenzyl)-2- (3-isopropoxy-5-(quinolin- 6-yl)benzylamino) nicotinamide
US10030016, Example 6.3 2-(3-(4-(cyclopropylamino) quinazolin-6-yl)benzylamino)- N-(3,4-difluorobenzyl)- nicotinamide BDBM281961
US10981893, Example 4 BDBM492875 N-((5-chloro-1H- indazol-3-yl)methyl)-5- (4- methylbenzyl) nicotinamide
US10981893, Example 6 5-(2-carbamoylbenzyl)- N-((5-chloro-1H- indazol-3- yl)methyl)nicotinamide BDBM492877
US12344595, Example 152 2-(4,4-difluoropiperidin-1-yl)-N-(3-(methylsulfonyl)phenyl)-5-(trifluoromethyl)nicotinamide BDBM754236
US12344595, Example 163 BDBM754247 5-cyclopropyl-2-(4,4- difluoroazepan-1-yl)- N-(3-sulfamoyl- phenyl)nicotinamide
US12344595, Example 173 BDBM754257 5-chloro-2-(4,4-difluoroazepan-1-yl)-N-(3-(methylsulfonyl)phenyl)nicotinamide
US12344595, Example 2 2-(azepan-1-yl)-5-chloro-4,6-dimethyl-N-(3-sulfamoylphenyl)nicotinamide BDBM754079
US12344595, Example 82 2-(azepan-1-yl)-N- (3- (methylsulfonyl) phenyl)-6-(trifluoro- methyl)nicotinamide BDBM754166
US12344595, Example 85 2-(azepan-1-yl)-N-(3-sulfamoylphenyl)-6-(trifluoromethoxy)-5-(trimethylsilyl)nicotinamide BDBM754169
N-[4-methoxy-3-(2-methylpropoxy)phenyl]-3-pyridinecarboxamide N-[4-methoxy-3-(2-methylpropoxy)phenyl]pyridine-3-carboxamide MLS001208112 SMR000515534 BDBM64007 N-(3-isobutoxy-4-methoxy-phenyl)nicotinamide cid_743159 N-(3-Isobutoxy-4-methoxy-phenyl)-nicotinamide
(R)-2,6-dimethyl-5-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinolin-2-yl)nicotinamide BDBM50319515 CHEMBL1085782
(R)-5-(N-ethyl-N-(2,2,2-trifluoro-1-(4- fluorophenyl)ethyl)sulfamoyl)nicotinamide US20250115569, Example 52 BDBM732509
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2-chlorophenyl)nicotinamide CHEMBL1099175 BDBM50317752
2-(4-(2-aminopyridin-3-yloxy) benzylamino)-5-cyano-N- (3,4-difluorobenzyl) nicotinamide US10030016, Example 313 BDBM282433
2-(4-(5-aminopyrazin- 2-yl)benzylamino)-5-cyano- N-(3,4-difluorobenzyl) nicotinamide US10030016, Example 377 BDBM282497
2-(4-(5-aminopyrazin- 2-yl)benzylamino)-N- (3,4-difluorobenzyl)-5- (trifluoromethyl) nicotinamide US10030016, Example 124 BDBM282244
2-(4-(5-aminopyrazin-2-yl) benzylamino)-N-(4- fluorophenyl)-5- (trifluoromethyl)nicotinamide BDBM282275 US10030016, Example 155
2-(4-(6-aminopyrimidin-4- yloxy)benzylamino)-5- cyano-N-(3,4- difluorobenzyl)nicotinamide US10030016, Example 314 BDBM282434
2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-nicotinamide BDBM50054705 CHEMBL141392
2-Benzyloxy-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-piperidin-1-yl-nicotinamide CHEMBL180028 BDBM50160135
2-methoxy-N-((5-(thiophen-2-yl)- 1,3,4-oxadiazol-2- yl)methyl)nicotinamide BDBM648314 US11884682, Compound 48
4-(2-methoxyphenyl)-6-methyl-N- (4,5,6,7-tetrahydrobenzo[d]thiazol-2- yl)nicotinamide BDBM758658 US20250230171, Compound 361
4-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide BDBM50317761 CHEMBL1098213
5-(4-Chloro-phenyl)-6-(2,4-dichloro-phenyl)-2-(3,4-difluoro-benzyloxy)-N-isopropyl-nicotinamide CHEMBL361020 BDBM50160132
5-bromo-N-((5-(3- methoxyphenyl)isoquinolin-8- yl)methyl)-2- (trifluoromethyl)nicotinamide BDBM360564 US9828369, Example 121
6-(2,3-difluorophenyl)-N-{3-[(morpholin-4-ylacetyl)amino]-4-(trifluoromethoxy)phenyl}nicotinamide BDBM300456 US10130633, Example 26
6-(2,6-difluorophenyl)-N-{3-[(morpholin-4-ylacetyl)amino]-4-(trifluoromethoxy)phenyl}nicotinamide US10130633, Example 29 BDBM300459
6-(3,5-difluorophenyl)-N-{3-[(morpholin-4-ylacetyl)amino]-4-(trifluoromethoxy)phenyl}nicotinamide US10130633, Example 27 BDBM300457
6-(3-acrylamidophenyl)-2-(4-phenoxyphenyl)nicotinamide US11840513, Example 1 US11345695, Example 1 BDBM389630 US9951056, Example 1
6-(3-fluorophenyl)-N-{4-methoxy-3-[(morpholin-4-ylacetyl)amino]phenyl}nicotinamide BDBM300462 US10130633, Example 32
6-(4-(4-acetylphenoxy) piperidine-1-carbonyl)- N-(4-(4-cyanophenoxy) cyclohexyl)nicotinamide BDBM328264 US9663496, Compound 402
6-(4-fluorophenyl)-N-{4- methoxy-3-[(morpholin-4- ylacetyl)amino]phenyl} nicotinamide BDBM300659 US10130633, Example 229
6-(tert-butyl)-5-chloro-2-(piperidin-1-yl)-N-(3-sulfamoylphenyl)nicotinamide US12344595, Example 40 BDBM754124
6-ethoxy-N-(4-(((2R,3R)-3-fluoroazetidin-2-yl)methyl)phenyl)nicotinamide US10023559, Example 122 BDBM283797
BDBM185359 US9670142, A117 6-(1H-indol-5-yl)-N-methyl-N-((1R,3S)-3-propionylamino-cyclopentyl)-nicotinamide
BDBM187307 US9670193, 19 N-(1-(dimethylamino)propan-2-yl)-6-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinamide
BDBM187399 US9670193, 20 (S)-N-(1-hydroxypropan-2-yl)-6-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinamide
BDBM282095 US10030016, Example 13 2-(4-(4-aminoquinazolin-6-yl)thiazol-2-ylamino)-N-(3,4-difluorobenzyl)-nicotinamide
BDBM282170 2-(3-carbamoyl-4-(1H-imidazol-1-yl)benzylamino)-N-(3,4-difluorobenzyl)nicotinamide US10030016, Example 50
BDBM282503 US10030016, Example 383 2-(4-(5-aminopyrazin-2- yl)benzylamino)-N-(4- fluorobenzyl)-5- (trifluoromethyl)nicotinamide
BDBM300460 6-(2-fluorophenyl)-N-{3-[(morpholin-4-ylacetyl)amino]-4-(trifluoromethoxy)phenyl}nicotinamide US10130633, Example 30
BDBM300461 6-(2-fluorophenyl)-N-{4-methoxy-3-[(morpholin-4-ylacetyl)amino]phenyl}nicotinamide US10130633, Example 31
BDBM360574 US9828369, Example 131 5-bromo-2-fluoro-N-((5-(3- methoxyphenyl)isoquinolin-8- yl)methyl)nicotinamide
BDBM407095 US10336762, Compound 34 6-(3-cyanopyrrolo[1,2-b] pyridazin-7- yl)-4-(isopropylamino)-N- (methylsulfonyl) nicotinamide
BDBM407520 N-(cyanomethyl)-6-(3- cyanopyrrolo[1,2-b] pyridazin-7-yl)-4- (isopropylamino) nicotinamide US10336762, Compound 462
BDBM407521 US10336762, Compound 463 N-(cyanomethyl)-6-(3- cyanopyrrolo[1,2-b] pyridazin-7-yl)-4- (methylamino)nicotinamide
BDBM409376 US10377742, Compound 402 6-(4-(4-acetylphenoxy)piperidine-1- carbonyl)-N-(4-(4- cyanophenoxy)cyclohexyl)nicotinamide
BDBM412391 4-methyl-N-(6-methyl-5-(3- (trifluoromethoxy)phenyl)pyrazin-2- yl)nicotinamide US10399967, Compound 21
BDBM432167 US10577360, Example 33 N-(1-Methylpiperidin-4-yl)-N-(1-phenyl-1H-pyrazol-3-yl)nicotinamide
BDBM492885 US10981893, Example 14 N-(4-carbamoylbenzyl)- 5-(4-((2-oxopyridin- 1(2H)- yl)methyl)benzyl) nicotinamide
BDBM492886 US10981893, Example 15 N-(4-chlorobenzyl)-5- (4-((2-oxopyridin- 1(2H)- yl)methyl)benzyl) nicotinamide
BDBM499371 6-((3-(6- (cyclopropylmethoxy)pyridin-3- yl)-5-fluorophenoxy)methyl)-N- (methylsulfonyl)nicotinamide US11020381, Example 64
BDBM50054711 4-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-nicotinamide CHEMBL342742
BDBM50165495 N-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phenyl]-6-pyrazol-1-yl-nicotinamide CHEMBL193903
BDBM50170414 N-[4-(3-Dimethylamino-pyrrolidin-1-yl)-phenyl]-6-(4-ethyl-piperazin-1-yl)-nicotinamide CHEMBL178731
BDBM50171588 N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-chloro-2-isobutylamino-nicotinamide CHEMBL364522
BDBM50191750 6-(4-fluoro-phenyl)-N-[3-(4-hydroxy-piperidin-1-ylmethyl)-quinolin-8-ylmethyl]-nicotinamide CHEMBL215873
BDBM50222817 5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-pyridin-4-yl-ethyl)-nicotinamide CHEMBL248836
BDBM50275674 CHEMBL487346 N-(2-aminophenyl)-6-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)nicotinamide
BDBM50287597 N-[(R)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2-mercapto-ethyl]-6-hydroxy-nicotinamide CHEMBL55931
BDBM50301327 CHEMBL570705 6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(4-fluorobenzyl)nicotinamide
BDBM50301336 6-(4-(1-benzylpiperidin-4-yl)piperazin-1-yl)-5-chloro-N-(2-phenoxyethyl)nicotinamide CHEMBL565559
BDBM50309191 2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)nicotinamide CHEMBL599171
BDBM50322982 CHEMBL1210206 6-chloro-N-(1-((2,6-diethoxy-4'-fluorobiphenyl-4-yl)methyl)piperidin-4-yl)nicotinamide
BDBM50322985 6-amino-N-(1-((2,6-diethoxy-4'-fluorobiphenyl-4-yl)methyl)piperidin-4-yl)nicotinamide CHEMBL1210142
BDBM550274 US11306081, Example 122 2-(4-(2-((1H- indazol-3-yl)- amino)-2- oxoethyl)-2- chlorophenoxy)- nicotinamide
BDBM654924 US11912693, Compound 537 5-(5-(2,2-diethyl-4-oxochroman-6-yl)- 1,2,4-oxadiazol-3-yl)nicotinamide
BDBM754130 N-(3- sulfamoylphenyl)-2- (4-azatricyclo- [4.3.1.13,8]undecan-4- yl)-5- (trifluoromethyl)- nicotinamide US12344595, Example 46
BDBM754164 US12344595, Example 80 2-(4,4- dimethylazepan-1- yl)-N-(3-sulfamoyl- phenyl)-5-(trifluoro- methyl)nicotinamide
CHEMBL1095873 2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide BDBM50317750
CHEMBL1223282 BDBM50325350 (R)-N-(3-(5-(1-cyclohexyl-2-(methylamino)-2-oxoethylcarbamoyl)furan-2-yl)benzyl)nicotinamide
CHEMBL168049 N-(2-Dimethylamino-ethyl)-5-{4-[3-(2-methoxy-5-trifluoromethyl-phenyl)-ureido]-phenoxy}-nicotinamide BDBM50139606
CHEMBL181875 BDBM50160125 5-(4-Chloro-phenyl)-6-(2,4-dichloro-phenyl)-2-(3,4-difluoro-benzyloxy)-N-methyl-nicotinamide
CHEMBL194759 BDBM50171571 N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-chloro-2-cyclobutylamino-nicotinamide
CHEMBL195006 5-Chloro-N-[1-(3-fluoro-4-methoxy-benzyl)-piperidin-4-yl]-2-isobutylamino-nicotinamide BDBM50171606
CHEMBL217699 BDBM50191751 6-(4-fluoro-phenyl)-N-[3-(4-methyl-piperazin-1-ylmethyl)-quinolin-8-ylmethyl]-nicotinamide
CHEMBL235651 N-(2-aminophenyl)-6-(5-(4-chlorophenyl)-2,5-diaza-bicyclo[2.2.1]heptan-2-yl)nicotinamide BDBM50220247
CHEMBL235652 N-(2-aminophenyl)-6-(5-(4-fluorophenyl)-2,5-diaza-bicyclo[2.2.1]heptan-2-yl)nicotinamide BDBM50220238
CHEMBL238212 BDBM50220255 N-(2-aminophenyl)-6-(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)nicotinamide
CHEMBL250671 BDBM50222827 5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-imidazol-1-yl-propyl)-nicotinamide
CHEMBL263215 BDBM50184134 N-[(S)-(ethyl-propyl-carbamoyl)-phenyl-methyl]-6-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-nicotinamide
CHEMBL274254 5-Chloro-N-[1-(2,3-dihydro-benzofuran-5-ylmethyl)-piperidin-4-yl]-2-isopropylamino-nicotinamide BDBM50171578
CHEMBL360104 5-(4-Chloro-phenyl)-6-(2,4-dichloro-phenyl)-2-(3,4-difluoro-benzyloxy)-N-ethyl-nicotinamide BDBM50160097
CHEMBL361003 2-Chloro-5-(4-chloro-phenyl)-6-(2,4-dichloro-phenyl)-N-piperidin-1-yl-nicotinamide BDBM50160140
CHEMBL384232 2-chloro-N-(4-(5-(2-chlorobenzamido)-1H-benzo[d]imidazol-2-yl)phenyl)nicotinamide BDBM50192199
CHEMBL425163 5-(4-Chloro-phenyl)-6-(2,4-dichloro-phenyl)-2-(3,4-difluoro-benzyloxy)-N-propyl-nicotinamide BDBM50160095
CHEMBL551127 BDBM50296559 N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]isoquinolin-1-yl)ethyl)nicotinamide
CHEMBL563911 N-(((S)-1-((R)-3-amino-4-(2-fluorophenyl)butanoyl)pyrrolidin-2-yl)methyl)nicotinamide BDBM50296126
CHEMBL570273 N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302139
N,N-dimethyl-2-(4-(1-methyl-1H-pyrazol-3-ylamino)quinazolin-6-yloxy)nicotinamide BDBM50300600 CHEMBL577592
N-((5-chloro-1H- indazol-3-yl)methyl)-5- (2- (trifluoromethyl)benzyl) nicotinamide BDBM492872 US10981893, Example 1
N-(1-((2,6-diethoxy-4'-fluorobiphenyl-4-yl)methyl)piperidin-4-yl)-6-(methylamino)nicotinamide CHEMBL1210209 BDBM50322979
N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-chloro-2-isopropylamino-nicotinamide CHEMBL365788 BDBM50171570
N-(2,4-difluoro-3-sulfamoylphenyl)-2-(4,4-difluoropiperidin-1-yl)-5-(trifluoromethyl)nicotinamide US12344595, Example 28 BDBM754112
N-(2-(2-phenyl-5-(trifluoromethyl)-1H-imidazole-4-carboxamido)ethyl)-6-(2,2,2-trifluoroethoxy)nicotinamide BDBM50341784 CHEMBL1766894
N-(2-aminophenyl)-6-(3-benzyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)nicotinamide CHEMBL393389 BDBM50220240
N-(2-aminophenyl)-6-(5-(3-phenylpropanoyl)-2,5-diaza-bicyclo[2.2.1]heptan-2-yl)nicotinamide CHEMBL399003 BDBM50220237
N-(cyanomethyl)-6-(3- cyanopyrrolo[1,2-b] pyridazin-7-yl)-4- (cyclopropylamino) nicotinamide US10336762, Compound 461 BDBM407519
N-[(S)-(benzyl-methyl-carbamoyl)-phenyl-methyl]-6-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-nicotinamide CHEMBL410089 BDBM50184121
N-[(S)-(butyl-methyl-carbamoyl)-phenyl-methyl]-6-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-nicotinamide BDBM50184107 CHEMBL245300
N-[3-(4-Pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-nicotinamide 2-Amino-pyrimidine, 19 CHEMBL418270 BDBM50290417
US10023559, Example 128 BDBM283803 6-ethoxy-N-(4-(((2S,3S)-3-fluoroazetidin-2-yl)methyl)phenyl)nicotinamide
US10030016, Example 368 BDBM282488 2-(4-(6-aminopyridin-3-yl) benzylamino)-5-cyano-N- (3,4-difluorobenzyl) nicotinamide
US10030016, Example 378 2-(4-(5-aminopyrazin-2- yl)benzylamino)-5-cyano- N-(4-fluorobenzyl) nicotinamide BDBM282498
US10030016, Example 5.6 BDBM281956 2-(3-(4-(aminoquinazolin- 6-yl)-5-isopropoxy- benzylamino)-N-(3,4- difluorobenzyl)nicotinamide
US10130633, Example 28 6-(3-fluorophenyl)-N-{3-[(morpholin-4-ylacetyl)amino]-4-(trifluoromethoxy)phenyl}nicotinamide BDBM300458
US10407409, Example 256 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(cyclobutylmethyl)nicotinamide BDBM413168
US10981893, Example 16 BDBM492887 N-(4-methoxybenzyl)- 5-(4-((2-oxopyridin- 1(2H)- yl)methyl)benzyl) nicotinamide
US10981893, Example 3 N-((5-chloro-1H- indazol-3-yl)methyl)-5- (4- (trifluoromethyl)benzyl) nicotinamide BDBM492874
US11241428, Example 1 N-(3-amino-6-phenylpyridin-2-yl)-6-(4-methylpiperazin-1-yl)nicotinamide. BDBM535852
US11241428, Example 22 BDBM535874 N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(3-cyanophenyl)nicotinamide
US11345695, Example 7 BDBM389634 US9951056, Example 7 US11840513, Example 7 6-(4-acrylamidophenyl)-2-(4-phenoxyphenyl)nicotinamide
US11957687, Compound 487 BDBM667467 6-(tert-butyl)-2-chloro-N- (3,6-dimethyl-9H-xanthen- 9-yl)nicotinamide
US12344595, Example 160 2-(4,4-difluoroazepan-1-yl)-5-(oxetan-3-yl)-N-(3-sulfamoylphenyl)nicotinamide BDBM754244
US12344595, Example 170 2-(4,4-difluoropiperidin-1-yl)-N-(2-fluoro-3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide BDBM754254
US20250115569, Example 53 BDBM732510 (S)-5-(N-ethyl-N-(2,2,2-trifluoro-1-(4- fluorophenyl)ethyl)sulfamoyl)nicotinamide
rac-N-(((3S,4S)-1-(3,4-dimethoxyphenethyl)-4-(4-methoxyphenyl)pyrrolidin-3-yl)methyl)nicotinamide BDBM50340161 CHEMBL1760075
BDBM754207 (R or S)-2-(4,4-Difluoro-3-methylpiperidin-1-yl)-N-(3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide (123) and (S or R)-2-(4,4-difluoro-3-methylpiperidin-1-yl)-N-(3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide US12344595, Example 123
BDBM754208 (R or S)-2-(4,4-Difluoro-3-methylpiperidin-1-yl)-N-(3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide (123) and (S or R)-2-(4,4-difluoro-3-methylpiperidin-1-yl)-N-(3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide US12344595, Example 124
BDBM77631 cid_650941 MLS000029810 N-(2-phenyl-1,3-benzoxazol-5-yl)-3-pyridinecarboxamide N-(2-phenyl-1,3-benzoxazol-5-yl)pyridine-3-carboxamide SMR000009926 N-(2-phenyl-1,3-benzoxazol-5-yl)nicotinamide N-(2-Phenyl-benzooxazol-5-yl)-nicotinamide
N-[2-(1,3-benzothiazol-2-yl)phenyl]pyridine-3-carboxamide SMR000178446 N-[2-(1,3-benzothiazol-2-yl)phenyl]nicotinamide BDBM63170 MLS000559257 N-(2-Benzothiazol-2-yl-phenyl)-nicotinamide cid_851526 N-[2-(1,3-benzothiazol-2-yl)phenyl]-3-pyridinecarboxamide
2-(2-phenylethylamino)-N-[3-(trifluoromethyl)phenyl]-3-pyridinecarboxamide SMR000200611 2-(phenethylamino)-N-[3-(trifluoromethyl)phenyl]nicotinamide MLS000581682 2-(2-phenylethylamino)-N-[3-(trifluoromethyl)phenyl]pyridine-3-carboxamide BDBM78164 2-[(2-phenylethyl)amino]-N-[3-(trifluoromethyl)phenyl]nicotinamide cid_2219338
BDBM56138 N-benzyl-2-(4-morpholinyl)nicotinamide 2-(4-morpholinyl)-N-(phenylmethyl)-3-pyridinecarboxamide N-benzyl-2-morpholin-4-ylpyridine-3-carboxamide cid_1441072 2-morpholin-4-yl-N-(phenylmethyl)pyridine-3-carboxamide N-benzyl-2-morpholino-nicotinamide MLS000065261 SMR000078890
BDBM69636 MLS001164432 SMR000496644 N-(4-tert-butyl-1,3-thiazol-2-yl)nicotinamide cid_697160 N-(4-tert-butyl-1,3-thiazol-2-yl)pyridine-3-carboxamide N-(4-tert-butyl-2-thiazolyl)-3-pyridinecarboxamide N-(4-tert-butylthiazol-2-yl)nicotinamide
(S)-2-(2-(1H-indol-6-yloxy) ethylamino)-N-(1-(3,4- difluorophenyl)ethyl) nicotinamide BDBM282137 US10030016, Example 19.1
(S)-2-(4-(6-aminopyridin- 3-yl)benzylamino)-N-(1- (3,4-difluorophenyl)ethyl) nicotinamide US10030016, Example 369 BDBM282489
(S)-6-(4-(2-(2-hydroxy-3-(2-oxoindolin-4-yloxy)propylamino)-2-methylpropyl)phenoxy)nicotinamide CHEMBL251167 BDBM50224026
4-(2-methoxyphenyl)-6-methyl-N- (4,5,6,7-tetrahydrothiazolo[5,4- c]pyridin-2-yl)nicotinamide BDBM758638 US20250230171, Compound 377
5-((2-Methyl-5-((3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)amino)nicotinamide (3) BDBM163698
5-(3-(2-methyl-5-((3- (trifluoromethyl)phenyl) carbamoyl)phenyl)pyrrolidin- 1-yl)nicotinamide BDBM708545 US20240425482, Example 17
5-(trifluoromethyl)-6-(8-(5-(trifluoromethyl)pyridin-2-ylamino)pyrido[2,3-b]pyrazin-3-yl)nicotinamide CHEMBL1214402 BDBM50323839
5-Bromo-2-ethoxy-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-6-methylamino-nicotinamide CHEMBL349146 BDBM50123799
5-Bromo-N-(1-ethyl-4-propyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide BDBM50123811 CHEMBL164000
5-Chloro-2-ethoxy-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-6-methylamino-nicotinamide CHEMBL164360 BDBM50123805
6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-iso- propyl-4-(isopropylamino) nicotinamide US10336762, Compound 369 BDBM407427
6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)-2-methylpiperazin-1-yl)-N-(3,4-difluorobenzyl)nicotinamide BDBM50337222 CHEMBL1681853
6-(4-(4-cyanophenoxy) piperidine-1-carbonyl)- N-((cis)-4-(4- fluorophenoxy) cyclohexyl)nicotinamide BDBM328186 US9663496, Compound 324
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(2,2,2-trifluoroethyl)nicotinamide US10407409, Example 77 BDBM412975
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(2,2-dimethylcyclopropyl)nicotinamide BDBM413265 US10407409, Example 54
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(2-fluoroethyl)nicotinamide BDBM412981 US10407409, Example 78
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(2-methylcyclopropyl)nicotinamide BDBM413204 US10407409, Example 262
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-isopropoxypropyl)nicotinamide BDBM413049 US10407409, Example 163
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-methoxypropyl)nicotinamide US10407409, Example 148 BDBM412964
6-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide BDBM50070572 CHEMBL290959
BDBM281766 US10030016, Example 1.5 2-(3-(1H-pyrrolo[2,3-b]pyridin- 3-yl)benzylamino)-N-(3,4- difluorobenzyl)nicotinamide
BDBM281767 US10030016, Example 1.6 2-(3-(1H-pyrrolo[2,3-b]pyridin- 3-yl)benzylamino)-N-(4- fluorobenzyl)nicotinamide
BDBM281813 US10030016, Example 2.35 2-(4-(1H-pyrazolo[3,4-b]pyridin- 5-yl)benzylamino)-N-(3,4- difluorobenzyl)nicotinamide
BDBM282141 US10030016, Example 21 2-(2-(9H-pyrido[2,3-b]indol- 7-yloxy)ethylamino)-N-(3,4- difluorobenzyl)nicotinamide
BDBM282493 2-(4-(6-aminopyridin-3- yl)benzylamino)-N-((5- fluoropyridin-3-yl) methyl)nicotinamide US10030016, Example 373
BDBM282513 US10030016, Example 393 2-(4-(1H-pyrazolo[3,4-b] pyridin-5-yl)benzylamino)- N-(4-fluorobenzyl) nicotinamide
BDBM392739 US10301297, Example 4 US11840513, Example 4 2-(4-phenoxyphenyl)-6-(piperazin-1-yl)nicotinamide US11345695, Example 4
BDBM409298 6-(4-(4-cyanophenoxy)piperidine-1- carbonyl)-N-((cis)-4-(4- fluorophenoxy)cyclohexyl)nicotinamide US10377742, Compound 324
BDBM412988 N-benzyl-6-(5-hydroxy-4-(pyridin-4-yl)-1H-pyrazol-1-yl)nicotinamide US10407409, Example 225
BDBM413043 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-ethoxypropyl)nicotinamide US10407409, Example 162
BDBM413054 US10407409, Example 91 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-morpholinopropyl)nicotinamide
BDBM50070565 CHEMBL39016 5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide
BDBM50070567 5-Bromo-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide CHEMBL287760
BDBM50070568 5-Bromo-6-dimethylamino-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide CHEMBL291296
BDBM50070573 CHEMBL38473 5-Chloro-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide
BDBM50070574 CHEMBL40903 5-Bromo-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide
BDBM50123813 CHEMBL351377 5-Bromo-2-methoxy-6-methylamino-N-(1-methyl-4-propyl-[1,4]diazepan-6-yl)-nicotinamide
BDBM50144401 CHEMBL67256 N-((1S,2S,4R)-1-Benzyl-2-hydroxy-6-methyl-4-methylcarbamoyl-heptyl)-5-bromo-nicotinamide
BDBM50171579 CHEMBL193576 N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-chloro-2-(cyclopropylmethyl-amino)-nicotinamide
BDBM50188704 CHEMBL210302 5-chloro-6-(4-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-piperazin-1-yl)nicotinamide
BDBM50191763 6-(4-fluoro-phenyl)-N-[3-((S)-3-hydroxy-pyrrolidin-1-ylmethyl)-quinolin-8-ylmethyl]-nicotinamide CHEMBL384079
BDBM50275770 CHEMBL513568 N-(2-amino-5-(thiophen-2-yl)phenyl)-6-(2,8-diazaspiro[4.5]decan-8-yl)nicotinamide
BDBM50276025 CHEMBL511625 N-(2-amino-5-(thiophen-2-yl)phenyl)-6-(spiro[indoline-3,4'-piperidine]-1'-yl)nicotinamide
BDBM50301347 CHEMBL579195 N-butyl-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)piperazin-1-yl)nicotinamide
BDBM50302119 N-(4-chloro-3-(5-methyl-1H-imidazol-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide CHEMBL572016
BDBM50331432 CHEMBL1289527 N-{3-[(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-phenyl-amino]-propyl}-nicotinamide
BDBM517397 USRE48711, Example 1 5-(2,5-difluorophenyl)-N-(3-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)nicotinamide
BDBM610204 N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)-6-(phenylamino)nicotinamide US9701664, Example 94
BDBM610212 N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)-6-(ethylamino)nicotinamide US9701664, Example 102
BDBM661266 US20240101548, Compound 219 4-((3-(5-chloropyrimidin-2- yl)-2-methoxyphenyl)amino)- 6-(cyclopropylcarboxamido)- N-ethoxy nicotinamide
BDBM731089 N-(6-(4-cyanophenyl)thiazolo[4,5-b]pyrazin-2-yl)-4-(2-methoxyphenyl)nicotinamide US20250122221, Compound 16
BDBM754228 US12344595, Example 144 (R)—N-(3-sulfamoylphenyl)-5-(trifluoromethyl)-2-(2-(trifluoromethyl)-1,4-oxazepan-4-yl) nicotinamide
BDBM754263 5-chloro-2-(4,4-difluoroazepan-1-yl)-N,4,6-trimethyl-N-(3-sulfamoylphenyl)nicotinamide US12344595, Example 179
CHEMBL1681867 BDBM50337235 (S)-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)-3-methylpiperazin-1-yl)nicotinamide
CHEMBL193489 BDBM50171575 5-Chloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-[(furan-2-ylmethyl)-amino]-nicotinamide
CHEMBL294635 N-[(S)-1-Benzyl-2-oxo-2-(3-oxo-2-phenylsulfanyl-pyrrolidin-1-yl)-ethyl]-nicotinamide BDBM50091870
CHEMBL485232 BDBM50274246 N-(1-(3-amino-3-oxopropyl)-5-(N-methylcyclohexanecarboxamido)-1H-benzo[d]imidazol-2-yl)nicotinamide
CHEMBL569817 N-(4-chloro-3-(pyrazolo[1,5-a]pyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide BDBM50302114
CHEMBL577409 BDBM50301348 N-benzyl-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)piperazin-1-yl)nicotinamide
CHEMBL578618 BDBM50302122 N-(4-chloro-3-(1-methyl-1H-pyrazol-3-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide
CHEMBL583270 BDBM50302117 N-(4-chloro-3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide
N-((4-((trans-4-(4-chlorophenyl)piperidin-3-yl)methoxy)-2,5-difluorophenyl)sulfonyl)nicotinamide US9630929, Example 103 BDBM323129
N-((cis)-4-(4- cyanophenoxy) cyclohexyl)-6-(4-(4- cyanophenoxy) piperidine-1- carbonyl)nicotinamide BDBM328183 US9663496, Compound 321
N-((cis)-4-(4- cyanophenoxy) cyclohexyl)-6-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)nicotinamide BDBM328194 US9663496, Compound 332
N-((cis)-4-(4-cyanophenoxy)cyclohexyl)-6- (4-(4-fluorobenzyl)piperazine-1- carbonyl)nicotinamide US10377742, Compound 332 BDBM409306
N-((cis)-4-(4-fluorophenoxy)cyclohexyl)-6- (4-(4-methoxybenzoyl)piperidine-1- carbonyl)nicotinamide BDBM409290 US10377742, Compound 316
N-(1-cyanopyrrolidin-3-yl)-6-(2- (pyridin-3-yl)pyrrolidin-1- yl)nicotinamide BDBM560961 US11390584, Example 21
N-(2-amino-5-(thiophen-3-yl)phenyl)-6-(2,8-diazaspiro[4.5]decan-8-yl)nicotinamide CHEMBL511797 BDBM50275824
N-(3,4-difluoro-5- sulfamoylphenyl)-2- (4,4-difluoropiperidin- 1-yl)-5-(trifluoro- methyl)nicotinamide US12344595, Example 171 BDBM754255
N-(4-(4-cyanophenoxy) cyclohexyl)-6-(4-(4- (methylsulfonyl) phenoxy)piperidine-1- carbonyl)nicotinamide BDBM328260 US9663496, Compound 398
N-(5-((cyclohexyl(methyl)amino)methyl)-1-(3-methoxypropyl)-1H-benzo[d]imidazol-2-yl)nicotinamide BDBM50275651 CHEMBL487357
N-(5-amino-[2,4′-bipyridin]-6-yl)-6-(4-methylpiperazin-1-yl)nicotinamide BDBM535863 US11241428, Example 8
US10030016, Example 1.8 BDBM281769 2-(3 -(1H-py rrolo[2,3-b]pyridin- 3-yl)benzylamino)-N- (cyclopentylmethyl)nicotinamide
US10030016, Example 370 2-(4-(6-aminopyridin-3-yl) benzylamino)-N-(3,4- difluorobenzyl)-5-(trifluoro- methyl)nicotinamide BDBM282490
US10030016, Example 380 (S)-2-(4-(5-aminopyrazin-2- yl)benzylamino)-N-(1-(3,4- difluorophenyl)ethyl) nicotinamide BDBM282500
US10030016, Example 5.5 BDBM281955 2-(3-(4-(cyclopropylamino) quinazolin-6-yl)-5-isopropoxy- benzylamino)-N-(3,4- difluorobenzyl)nicotinamide
US10030016, Example 6.2 BDBM281960 2-(3-(7H-pyrrole[2,3-d] pyrimidin-5-yl)benzylamino)- N-(3,4-difluorobenzyl) nicotinamide
US10336762, Compound 21 6-(3-cyanopyrrolo[1,2-b] pyridazin-7- yl)-4-(isopropylamino)-N-(4- sulfamoylphenethyl) nicotinamide BDBM407082
US10377742, Compound 321 BDBM409295 N-((cis)-4-(4-cyanophenoxy)cyclohexyl)-6- (4-(4-cyanophenoxy)piperidine-1- carbonyl)nicotinamide
US10377742, Compound 398 N-(4-(4-cyanophenoxy)cyclohexyl)-6-(4-(4- (methylsulfonyl)phenoxy)piperidine-1- carbonyl)nicotinamide BDBM409372
US10377742, Compound 74 BDBM327932 US9663496, Compound 74 6-(4-benzylpiperazine-1- carbonyl)-N-(1- benzylpiperidin-4- yl)nicotinamide
US10407409, Example 145 BDBM413373 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-methoxybutyl)nicotinamide
US10407409, Example 202 BDBM413279 N-(tert-butyl)-6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinamide
US10407409, Example 235 BDBM413044 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(4-methoxybutyl)nicotinamide
US10407409, Example 265 BDBM413220 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3,3-difluorocyclobutyl)nicotinamide
US10407409, Example 53 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(2-cyclopropylethyl)nicotinamide BDBM413259
US10407409, Example 80 BDBM412992 N-(sec-butyl)-6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinamide
US10407409, Example 84 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(4,4-difluorocyclohexyl)nicotinamide BDBM413014
US11241428, Example 25 N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(piperazin-1-yl)nicotinamide BDBM535876
US11390584, Example 18 6-(4-carbamoylpiperidin-1-yl)-N- (1-cyanopyrrolidin-3- yl)nicotinamide US11053198, Example 18 BDBM514229
US11390584, Example 23 N-(1-cyanopyrrolidin-3-yl)-6-(4- (pyridin-4-yl)piperidin-1- yl)nicotinamide BDBM560963
US9663496, Compound 316 BDBM328178 N-((cis)-4-(4- fluorophenoxy) cyclohexyl)-6-(4-(4- methoxybenzoyl) piperidine-1- carbonyl)nicotinamide
US9670142, A153 6-(6-chloro-benzoxazol-2-yl)-N-methyl-N-((1R,3S)-3-propionylamino-cyclopentyl)-nicotinamide BDBM186312
US9670193, 18 (R)-N-(1-(dimethylamino)propan-2-yl)-6-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinamide BDBM187246
US9670193, 23 (R)-N-(1-(diethylamino)propan-2-yl)-6-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinamide BDBM187565
US9701664, Example 104 BDBM610216 6-amino-N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)nicotinamide
BDBM96319 MLS000592118 N-[(o-toluoylamino)thiocarbamoyl]nicotinamide N-[[(2-methylbenzoyl)amino]carbamothioyl]pyridine-3-carboxamide N-[N'-(2-Methyl-benzoyl)-hydrazinocarbothioyl]-nicotinamide N-[[[(2-methylphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-3-pyridinecarboxamide N-[[(2-methylphenyl)carbonylamino]carbamothioyl]pyridine-3-carboxamide cid_3817775 SMR000218332
N-[(2-phenylethanoylamino)carbamothioyl]pyridine-3-carboxamide N-[[(2-phenylacetyl)amino]thiocarbamoyl]nicotinamide BDBM96355 N-[[(1-oxo-2-phenylethyl)hydrazo]-sulfanylidenemethyl]-3-pyridinecarboxamide SMR000431764 cid_1979036 N-[[(2-phenylacetyl)amino]carbamothioyl]pyridine-3-carboxamide N-(N'-Phenylacetyl-hydrazinocarbothioyl)-nicotinamide MLS000768443
N-benzyl-2-[(3-methoxyphenyl)amino]nicotinamide N-benzyl-2-(3-methoxyanilino)pyridine-3-carboxamide cid_1440965 MLS000051058 SMR000078885 BDBM50834 2-[(3-methoxyphenyl)amino]-N-(phenylmethyl)pyridine-3-carboxamide N-benzyl-2-(m-anisidino)nicotinamide 2-(3-methoxyanilino)-N-(phenylmethyl)-3-pyridinecarboxamide
(R)-5-(3-(2-methyl-5- ((3-(trifluoromethyl) phenyl)carbamoyl)phenyl) pyrrolidin-1- yl)nicotinamide BDBM708546 US20240425482, Example 18
(S)-6-(4-(2-(3-(3,3-dibenzyl-2-oxoindolin-4-yloxy)-2-hydroxypropylamino)-2-methylpropyl)phenoxy)nicotinamide BDBM50224027 CHEMBL250579
2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(5-fluoropyridin-2-yl)nicotinamide CHEMBL1099204 BDBM50317754
2-(Difluoromethyl)-5-((2-methylpropanoylamino)methyl)-N-(2-(4-(trifluoromethyl)phenyl)benzofuran-5-yl)nicotinamide BDBM286054 US10081629, Example 39
2-{4-[5-(2,4-Dichloro-benzylcarbamoyl)-thiophen-2-ylmethyl]-piperazin-1-yl}-N-methyl-nicotinamide BDBM342644 US9776991, Example 14
4-(2-methoxyphenyl)-6-methyl-N-(6- oxo-4,5,6,7-tetrahydrobenzo[d]thiazol- 2-yl)nicotinamide US20250230171, Compound 373 BDBM758652
4-methyl-N-(5-(2-methyl-5-(pyridin- 2-yloxy)phenyl)pyridin-2- yl)nicotinamide US10399967, Compound 32 BDBM412402
4-methyl-N-(5-(2-methyl-5-(pyridin- 3-ylethynyl)phenyl)pyrazin-2- yl)nicotinamide US10399967, Compound 44 BDBM412414
4-methyl-N-(5-(5-(pyridin-2-yloxy)- 2-(trifluoromethoxy)phenyl)pyrazin- 2-yl)nicotinamide BDBM412421 US10399967, Compound 51
4-methyl-N-(5-(6- methylbenzo[d][1,3]dioxol-5- yl)pyrazin-2-yl)nicotinamide BDBM412420 US10399967, Compound 50
5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide CHEMBL38969 BDBM50070569
5-benzo[1,3]dioxol-5-yl-2-chloro-N-[4-(4-methyl-piperazin-1-ylmethyl)-phenyl]-nicotinamide CHEMBL199298 BDBM50181678
5-chloro-6-(4-(1-(3-cyanobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide CHEMBL587391 BDBM50301337
5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide BDBM50301340 CHEMBL565760
5-chloro-6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide BDBM50301335 CHEMBL568676
5-chloro-6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(4-fluorobenzyl)nicotinamide BDBM50301326 CHEMBL565980
5-chloro-6-(4-(1-(4-methoxybenzyl)piperidin-4-yl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide BDBM50301344 CHEMBL565970
5-chloro-6-(4-(3-((4-chlorophenyl)(methyl)amino)propyl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide BDBM50301334 CHEMBL569336
6-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)nicotinamide US11840513, Example 3 BDBM389631 US11345695, Example 3 US9951056, Example 3
6-(2-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)propanoyl]amino}-4- (trifluoromethoxy)phenyl] nicotinamide BDBM300643 US10130633, Example 213
6-(2-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)propanoyl]amino}-4- (trifluoromethoxy)phenyl] nicotinamide BDBM300654 US10130633, Example 224
6-(3,5-difluorophenyl)-N-[3-{[2- (morpholin-4- yl)propanoyl]amino}-4- (trifluoromethoxy)phenyl] nicotinamide BDBM300649 US10130633, Example 219
6-(3,5-difluorophenyl)-N-[3-{[2- (morpholin-4- yl)propanoyl]amino}-4- (trifluoromethoxy)phenyl] nicotinamide US10130633, Example 203 BDBM300633
6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-4-(isopropyl- amino)-N-(2- sulfamoylethyl)nicotinamide US10336762, Compound 20 BDBM407081
6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(cyclobutylmethyl)nicotinamide US10407409, Example 180 BDBM413149
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-((3,3-difluorocyclobutyl)methyl)nicotinamide US10407409, Example 264 BDBM413215
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-((3-methylcyclobutyl)methyl)nicotinamide US10407409, Example 257 BDBM413174
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(2-ethoxy ethyl)nicotinamide US10407409, Example 112 BDBM413178
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-(dimethylamino)propyl)nicotinamide US10407409, Example 269 BDBM413244
6-(4-acryloylpiperazin-1-yl)-2-(4-phenoxyphenyl)nicotinamide US11840513, Example 5 US9951056, Example 5 US11345695, Example 5 BDBM389632
6-Methyl-N-(1-methylpiperidin-4-yl)-N-(1-phenyl-1H-pyrazol-3-yl)nicotinamide BDBM432170 US10577360, Example 36
6-amino-N-(1-((2-(benzyloxy)-6-ethoxy-4'-fluorobiphenyl-4-yl)methyl)piperidin-4-yl)nicotinamide BDBM50322978 CHEMBL1210210
6-chloro-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)nicotinamide CHEMBL386917 BDBM50200027
6-chloro-N-(4-(4-(cyclopropyl(hydroxy)methylene)-1-(4-fluorobenzyl)-3,5-dioxopyrrolidin-2-yl)butyl)nicotinamide CHEMBL485703 BDBM50279373
BDBM185567 US9670142, A135 6-(4-fluoro-1H-indol-5-yl)-N-methyl-N-((1R,3S)-3-propionylamino-cyclopentyl)-nicotinamide
BDBM186090 US9670142, A140 5-fluoro-6-(1H-indol-5-yl)-N-methyl-N-((1R,3S)-3-propionylamino-cyclopentyl)-nicotinamide
BDBM186316 US9670142, A157 6-(7-fluoro-1H-indol-6-yl)-N-methyl-N-((1R,3S)-3-propionylamino-cyclopentyl)-nicotinamide
BDBM187547 US9670193, 22 (R)-N-(1-(diethylamino)-3-methylbutan-2-yl)-6-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinamide
BDBM281768 US10030016, Example 1.7 2-(3-(1H-pyrrolo[2,3-b]pyridin- 3-yl)benzylamino)-N-(4- (trifluoromethyl)benzyl) nicotinamide
BDBM281974 US10030016, Example 7.1 2-(((5-(4-aminoquinazolin- 6-yl)thiazol-2-yl)methyl) amino)-N-(3,4- difluorobenzyl)nicotinamide
BDBM282349 US10030016, Example 229 N-(3,4-difluorobenzyl)-2-(4-(5-(2-hydroxyethylamino)pyrazin-2-yl)benzylamino)-5-(trifluoromethyl)nicotinamide
BDBM298597 US10125118, Example 3 2-amino-N-(trans-2-(benzyloxy)cyclopentyl)-5-(1-methyl-1H-pyrazol-4-yl)nicotinamide
BDBM300620 6-(3-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)propanoyl]amino}-4- (trifluoromethoxy)phenyl] nicotinamide US10130633, Example 190
BDBM300631 US10130633, Example 201 6-(3-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)propanoyl]amino}-4- (trifluoromethoxy)phenyl] nicotinamide
BDBM328197 6-(4-(4-cyanophenoxy) piperidine-1-carbonyl)- N-(piperidin-4- yl)nicotinamide US9663496, Compound 335 US10377742, Compound 335
BDBM328307 US9663496, Compound 445 US10377742, Compound 445 6-(4-(4-methoxybenzoyl) piperidine-1-carbonyl)- N-(piperidin-4- yl)nicotinamide
BDBM389623 US11840513, Example 33 6-(4-acryloylpiperazin-1-yl)-2-(4-chlorophenyl)nicotinamide US11345695, Example 33 US9951056, Example 33
BDBM402053 US10011595, B-11 N-(2-((4,6-dimethylpyrimidin-2- yl)(methyl)amino)ethyl)-N-ethyl-2- (2,2,2-trifluoroethoxy)nicotinamide
BDBM409289 N-((1s,4s)-4-(4-cyanophenoxy)cyclohexyl)- 6-(4-(4-methoxybenzoyl)piperidine-1- carbonyl)nicotinamide US10377742, Compound 315
BDBM412987 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(2-methoxy ethyl)nicotinamide US10407409, Example 152
BDBM413042 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(2-isopropoxy ethyl)nicotinamide US10407409, Example 89
BDBM413050 US10407409, Example 236 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(2-(trifluoromethoxy)ethyl)nicotinamide
BDBM413192 US10407409, Example 260 (S)-6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(1-cyclopropylethyl)nicotinamide
BDBM413209 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-((1-fluorocyclohexyl)methyl)nicotinamide US10407409, Example 263
BDBM413291 N-cyclopropyl-6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)nicotinamide US10407409, Example 204
BDBM492893 US10981893, Example 22 N-((6-amino-2,4- dimethylpyridin-3- yl)methyl)-5-((3- chloroquinolin-6- yl)methyl)nicotinamide
BDBM50070564 CHEMBL432284 5-Chloro-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide
BDBM50139599 5-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido]-phenoxy}-N-(2-morpholin-4-yl-ethyl)-nicotinamide CHEMBL164693
BDBM50171594 N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-chloro-2-(3-isopropoxy-propylamino)-nicotinamide CHEMBL196223
BDBM50190080 N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-nicotinamide CHEMBL215997
BDBM50204832 4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N-(3-(2-oxopyrrolidin-1-yl)propyl)nicotinamide CHEMBL234655
BDBM502166 6-chloro-N- [4-(1- methyl- [1,2,4] triazolo [4,3-a] quinoxaline- 4-ylamino)- butyl]- nicotinamide US11028090, Example 20
BDBM50224021 CHEMBL251372 (S)-6-(4-(2-(3-(3,3-dimethyl-2-oxoindolin-4-yloxy)-2-hydroxypropylamino)-2-methylpropyl)phenoxy)nicotinamide
BDBM50224023 CHEMBL251579 (S)-6-(4-(2-(3-(3,3-diethyl-2-oxoindolin-4-yloxy)-2-hydroxypropylamino)-2-methylpropyl)phenoxy)nicotinamide
BDBM50263674 N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide CHEMBL476774
BDBM50301338 5-chloro-6-(4-(1-(2-cyanobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide CHEMBL587013
BDBM50301339 5-chloro-6-(4-(1-(4-cyanobenzoyl)piperidin-4-yl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide CHEMBL570356
BDBM50317759 CHEMBL1097868 2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-5-bromo-N-(2,4-difluorophenyl)nicotinamide
BDBM50323418 N-(2-(3-(3-tert-butyl-5-(3-phenylureido)-1H-pyrazol-1-yl)benzylamino)-2-oxoethyl)nicotinamide CHEMBL1209276
BDBM50337217 CHEMBL1681848 5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(3,4-difluorobenzyl)nicotinamide
BDBM549164 2-((6-((5- cyano- pyrimidin- 2- yl)amino) spiro[3.3] heptan-2- yl)oxy) nicotinamide US11299488, Example 55
BDBM627132 US11787802, Example 138 2-(3-Methoxyphenyl)-N-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)nicotinamide
BDBM708547 (S)-5-(3-(2-methyl-5- ((3-(trifluoromethyl) phenyl)carbamoyl)phenyl) pyrrolidin-1- yl)nicotinamide US20240425482, Example 19
BDBM754163 2-(6- azaspiro[2.6]nonan- 6-yl)-N-(3- sulfamoyl-phenyl)-5- (trifluoro- methyl)nicotinamide US12344595, Example 79
CHEMBL1094898 BDBM50317402 5-(Aminosulfonyl)-N-(2-phenylethyl)-2-(phenylthio)-nicotinamide N-(2-phenylethyl)-2-(phenylsulfanyl)-5-sulfamoylpyridine-3-carboxamide
CHEMBL1097543 2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2-(2-hydroxyethyl)phenyl)nicotinamide BDBM50317756
CHEMBL112528 BDBM50148736 N-(2-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3.2.1]oct-8-yl}-ethyl)-nicotinamide
CHEMBL140620 BDBM50013197 N-[5-(2-Fluoro-phenyl)-1-methyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-ylmethyl]-nicotinamide
CHEMBL352072 BDBM50139602 5-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureido]-phenoxy}-N-(2-morpholin-4-yl-ethyl)-nicotinamide
CHEMBL362192 5-(4-Chloro-phenyl)-6-(2,4-dichloro-phenyl)-2-(3,4-difluoro-benzyloxy)-N-(2-fluoro-ethyl)-nicotinamide BDBM50160131
CHEMBL401335 6-(4-(2-((S)-3-(3-benzyl-2-oxoindolin-4-yloxy)-2-hydroxypropylamino)-2-methylpropyl)phenoxy)nicotinamide BDBM50224029
CHEMBL40497 BDBM50070566 5-Bromo-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide
CHEMBL416047 5-Bromo-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide BDBM50070571
CHEMBL427188 BDBM50181677 5-benzo[1,3]dioxol-5-yl-2-methoxy-N-[4-(4-methyl-piperazin-1-ylmethyl)-phenyl]-nicotinamide
CHEMBL455445 BDBM50248022 5-chloro-N-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-yl)-6-(piperidin-1-yl)nicotinamide
CHEMBL472251 BDBM50275826 N-(2-amino-5-(1H-pyrazol-3-yl)phenyl)-6-(2,8-diazaspiro[4.5]decan-8-yl)nicotinamide
CHEMBL521224 6-{[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]-2-oxoethyl}amino)ethyl]amino}nicotinamide BDBM50242577
CHEMBL565968 5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(3-methoxybenzyl)nicotinamide BDBM50301350
CHEMBL568668 5-chloro-6-(4-(1-(4-fluorobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide BDBM50301342
CHEMBL570509 BDBM50301332 5-chloro-6-(4-(4-(4-chlorobenzyl)piperazin-1-yl)piperidin-1-yl)-N-(3,4-dichlorobenzyl)nicotinamide
CHEMBL578546 6-(4-(1-(4-bromobenzyl)piperidin-4-yl)piperazin-1-yl)-5-chloro-N-(2-phenoxyethyl)nicotinamide BDBM50301341
CHEMBL578779 5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)piperazin-1-yl)-N-(3,4-dichlorobenzyl)nicotinamide BDBM50301351
MLS001035529 SMR000669187 BDBM58520 N-(3-benzamidophenyl)pyridine-3-carboxamide N-(3-benzamidophenyl)-3-pyridinecarboxamide N-(3-benzamidophenyl)nicotinamide cid_1248054
N-((1s,4s)-4-(4- cyanophenoxy) cyclohexyl)-6-(4-(4- methoxybenzoyl) piperidine-1- carbonyl)nicotinamide US9663496, Compound 315 BDBM328177
N-((R)-3-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-3-phenylmethanesulfonylamino-propyl)-nicotinamide CHEMBL117678 BDBM50083752
N-((cis)-4-(4-cyanophenoxy)cyclohexyl)-6- (4-(3- (cyclopropanecarboxamido)phenoxy) piperidine-1-carbonyl)nicotinamide BDBM409408 US10377742, Compound 434
N-(3-amino-6-(3,4-difluorophenyl)pyridin-2-yl)-6-(4-methylpiperazin-1-yl)nicotinamide US11241428, Example 9 BDBM535864
N-(3-amino-6-(4-methoxyphenyl)pyridin-2-yl)-6-(4-methylpiperazin-1-yl)nicotinamide BDBM535862 US11241428, Example 7
N-(3-methoxypropyl)-2-(phenylsulfanyl)-5-sulfamoylpyridine-3-carboxamide 5-(Aminosulfonyl)-N-(3-methoxypropyl)-2-(phenylthio)-nicotinamide BDBM50317400 CHEMBL1099124
N-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-4-yloxy)-3-fluorophenyl)nicotinamide BDBM50235575 CHEMBL253222
N-Methyl-2-{4-[5-(2-trifluoromethoxy-benzylcarbamoyl)-thiophen-2-ylmethyl]-piperazin-1-yl}-nicotinamide BDBM342765 US9776991, Example 135
N-[(R)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2-mercapto-ethyl]-6-pyrrol-1-yl-nicotinamide BDBM50287602 CHEMBL57056
N-benzyl-6-(4-(2-chloro-4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinamide BDBM413243 US10407409, Example 196
N-benzyl-6-(4-(4-cyano-2-fluorophenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinamide BDBM412959 US10407409, Example 220
N-benzyl-6-(4-(4-cyano-2-methoxyphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinamide BDBM413237 US10407409, Example 195
N-cyclobutyl-6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)nicotinamide BDBM413024 US10407409, Example 13
N-ethyl-6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)nicotinamide BDBM413147 US10407409, Example 34
US10030016, Example 355 BDBM282475 2-(4-(6-amino-5-methylpyridin-3-yl)benzylamino)-N-(3,4-difluorobenzyl)-5-(trifluoromethyl)nicotinamide
US10081629, Example 40 2-(Difluoromethyl)-5-((2-methylpropanoylamino)methyl)-N-(2-(4-(trifluoromethyl)phenyl)isoindolin-5-yl)nicotinamide BDBM286055
US10336762, Compound 45 6-(3-cyanopyrrolo[1,2-b] pyridazin-7- yl)-N-(2-(hydroxymethyl) cyclopropyl)- 4-(isopropylamino) nicotinamide BDBM407106
US10336762, Compound 460 BDBM407518 N-(cyanomethyl)-6-(3- cyanopyrrolo[1,2-b] pyridazin-7-yl)-4- (oxetan-3-ylamino) nicotinamide
US10336762, Compound 92 BDBM407153 6-(3-cyanopyrrolo[1,2-b] pyridazin-7- yl)-4-(isopropylamino)-N-(2- (methylsulfonyl)ethyl) nicotinamide
US10407409, Example 118 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-(cyclopropylmethoxy)propyl)nicotinamide BDBM413213
US10407409, Example 149 BDBM412970 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(1-(methoxymethyl)cyclopentyl)nicotinamide
US10407409, Example 188 BDBM413197 N-benzyl-6-(4-(4-cyano-3-fluorophenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinamide
US10407409, Example 199 BDBM413261 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(1-(methoxymethyl)cyclobutyl)nicotinamide
US10407409, Example 2 N-benzyl-6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)nicotinamide BDBM412962
US10407409, Example 201 BDBM413273 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(1-(methoxymethyl)cyclopropyl)nicotinamide
US10407409, Example 217 6-(4-(4-(cyanomethyl)phenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-methoxypropyl)nicotinamide BDBM413369
US10407409, Example 268 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(2-(dimethylamino)ethyl)nicotinamide BDBM413238
US11241428, Example 27 BDBM535877 N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-aminopiperidin-1-yl)nicotinamide
US11299488, Example 28 2-(((2S,4s, 6S)-6- (quinazolin- 2- ylamino) spiro [3.3] heptan-2- yl)oxy) nicotinamide BDBM549093
US11345695, Example 9 BDBM389627 US9951056, Example 9 6-(4-acrylamidopiperidin-1-yl)-2-(4-phenoxyphenyl)nicotinamide US11840513, Example 9
US11840513, Example 10 BDBM389636 6-(3-acrylamidopyrrolidin-1-yl)-2-(4-phenoxyphenyl)nicotinamide US9951056, Example 10 US11345695, Example 10
US12344595, Example 161 5-(but-3-en-1-yl)-2-(4,4-difluoroazepan-1-yl)-N-(3-sulfamoylphenyl)nicotinamide BDBM754245
US12344595, Example 83 N-(3-carbamoyl- phenyl)-2-(6- azaspiro[2.5]octan- 6-yl)-6-(trifluoro- methyl)- nicotinamide BDBM754167
US12344595, Example 87 2-(2-oxa-7-azaspiro- [3.5]nonan-7-yl)-N-(3- sulfamoylphenyl)-5- (trimethylsilyl)- nicotinamide BDBM754171
US9670142, A134 6-(7-fluoro-1H-indol-5-yl)-N-methyl-N-((1R,3S)-3-propionylamino-cyclopentyl)-nicotinamide BDBM185566
US9670142, A144 6-imidazo[1,2-a]pyridin-6-yl-N-methyl-N-((1R,3S)-3-propionylamino-cyclopentyl)-nicotinamide BDBM186095
US9670142, A169 6-(3-fluoro-1H-indol-5-yl)-N-methyl-N-((1R,3S)-3-propionylamino-cyclopentyl)-nicotinamide BDBM186330
cid_532822 BDBM45798 N-(2,5-dimethoxyphenyl)pyridine-3-carboxamide MLS-0091938.0001 N-(2,5-dimethoxyphenyl)-3-pyridinecarboxamide N-(2,5-dimethoxyphenyl)nicotinamide
give 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(1-methylcyclopropyl)nicotinamide BDBM413255 US10407409, Example 198
2-(4-methyl-3-nitroanilino)pyridine-3-carboxamide 2-[(4-methyl-3-nitro-phenyl)amino]pyridine-3-carboxamide 2-(4-methyl-3-nitro-anilino)nicotinamide cid_901926 MLS000700314 2-{3-nitro-4-methylanilino}nicotinamide 2-(4-methyl-3-nitroanilino)-3-pyridinecarboxamide BDBM115007 SMR000226870
2-(azepan-1-yl)-N-cyclopentyl-nicotinamide 2-(azepan-1-yl)-N-cyclopentyl-pyridine-3-carboxamide 2-Azepan-1-yl-N-cyclopentyl-nicotinamide cid_650023 2-(1-azepanyl)-N-cyclopentyl-3-pyridinecarboxamide MLS000029492 2-(azepan-1-yl)-N-cyclopentylpyridine-3-carboxamide SMR000003787 BDBM42595
6-(6-chloropyrazolo[1,5-a]pyrimidin-3-yl)-N-(2-fluoro-2-(3-hydroxyoxetan-3-yl)ethyl)-4-(isopropylamino)nicotinamide & 6-(6-chloropyrazolo[1,5-a]pyrimidin-3-yl)-N-(2-fluoro-3,4-dihydroxy-3-(hydroxymethyl)butyl)-4-(isopropylamino)nicotinamide US10618903, Example 9 BDBM438381
BDBM40796 N-(2-oxidanylidenechromen-6-yl)pyridine-3-carboxamide MLS000075075 N-(2-oxo-1-benzopyran-6-yl)-3-pyridinecarboxamide N-(2-Oxo-2H-chromen-6-yl)-nicotinamide cid_650372 N-(2-oxochromen-6-yl)pyridine-3-carboxamide N-(2-ketochromen-6-yl)nicotinamide SMR000014853
MLS000099216 N-(5-butyramido-2-chloro-phenyl)nicotinamide BDBM62721 cid_893089 N-[2-chloro-5-(1-oxobutylamino)phenyl]-3-pyridinecarboxamide N-[5-(butyrylamino)-2-chlorophenyl]nicotinamide N-[5-(butanoylamino)-2-chloranyl-phenyl]pyridine-3-carboxamide N-[5-(butanoylamino)-2-chlorophenyl]pyridine-3-carboxamide SMR000073407
MLS000768437 SMR000431758 BDBM96353 N-[[(4-fluorobenzoyl)amino]thiocarbamoyl]nicotinamide N-[N'-(4-Fluoro-benzoyl)-hydrazinocarbothioyl]-nicotinamide cid_1980622 N-[[(4-fluorophenyl)carbonylamino]carbamothioyl]pyridine-3-carboxamide N-[[[(4-fluorophenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-3-pyridinecarboxamide N-[[(4-fluorobenzoyl)amino]carbamothioyl]pyridine-3-carboxamide
N-[[(2,4-dichlorophenyl)carbonylamino]carbamothioyl]pyridine-3-carboxamide MLS000589712 BDBM57518 cid_1758310 N-[[(2,4-dichlorobenzoyl)amino]carbamothioyl]pyridine-3-carboxamide N-[[[(2,4-dichlorophenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-3-pyridinecarboxamide SMR000219492 N-[N'-(2,4-Dichloro-benzoyl)-hydrazinocarbothioyl]-nicotinamide N-[[(2,4-dichlorobenzoyl)amino]thiocarbamoyl]nicotinamide
N-[[[(2-chlorophenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-3-pyridinecarboxamide MLS000589713 N-[[(2-chlorobenzoyl)amino]thiocarbamoyl]nicotinamide BDBM59937 N-[N'-(2-Chloro-benzoyl)-hydrazinocarbothioyl]-nicotinamide N-[[(2-chlorobenzoyl)amino]carbamothioyl]pyridine-3-carboxamide SMR000219491 cid_1865535 N-[[(2-chlorophenyl)carbonylamino]carbamothioyl]pyridine-3-carboxamide
cid_1265057 SMR000136201 N-(6-piperidinosulfonyl-1,3-benzothiazol-2-yl)nicotinamide N-(6-piperidin-1-ylsulfonyl-1,3-benzothiazol-2-yl)pyridine-3-carboxamide BDBM74722 N-[6-(1-piperidinylsulfonyl)-1,3-benzothiazol-2-yl]-3-pyridinecarboxamide MLS000531223 N-[6-(1-piperidinylsulfonyl)-1,3-benzothiazol-2-yl]nicotinamide
(R)-6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-4- (isopropylamino)- N-(tetrahydrofuran-3-yl) nicotinamide BDBM407098 US10336762, Compound 37
5-chloro-6-(4-(1-(4-chlorobenzyl)-4-methylpiperidin-4-yl)piperazin-1-yl)-N-(3,4-dichlorobenzyl)nicotinamide CHEMBL1681856 BDBM50337224
5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)-3-oxopiperazin-1-yl)-N-(3,4-difluorobenzyl)nicotinamide CHEMBL1681857 BDBM50337225
6-(1-acetyl-1,8-diazaspiro[4.5]decan-8-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide BDBM50275987 CHEMBL471400
6-(1-acryloylpiperidin-4-yl)-2-(4-(phenylcarbamoyl)phenyl)nicotinamide US9951056, Example 61 BDBM389681 US11345695, Example 61 US11840513, Example 61
6-(2-fluorophenyl)-N-[4-methoxy-3-({[1-(morpholin-4-yl)cyclopropyl]carbonyl}amino)phenyl]nicotinamide BDBM300492 US10130633, Example 62
6-(3,5-difluorophenyl)-N-[3-({[1-(morpholin-4-yl)cyclopropyl]carbonyl}amino)-4-(trifluoromethoxy)phenyl]nicotinamide BDBM300490 US10130633, Example 60
6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-(iso- propylamino)-N-(4- (methylsulfonyl)cyclohexyl) nicotinamide US10336762, Compound 521 BDBM407579
6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-4- (isopropylamino)- N-(3-methoxy- 3-methylbutyl)nicotinamide BDBM407148 US10336762, Compound 87
6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-((1R,3R)- 3-hydroxycyclopentyl)- 4-(isopropylamino) nicotinamide BDBM407247 US10336762, Compound 188
6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-((1S,3S)- 3-hydroxycyclohexyl)-4- (isopropylamino) nicotinamide US10336762, Compound 191 BDBM407250
6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-((1S,3S)- 3-hydroxycyclopentyl)- 4-(isopropylamino) nicotinamide US10336762, Compound 189 BDBM407248
6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-(1,1- dioxidotetrahydrothiophen- 3-yl)-4-(isopropylamino) nicotinamide BDBM407182 US10336762, Compound 123
6-(4-(2-((S)-2-hydroxy-3-(3-isopropyl-2-oxoindolin-4-yloxy)propylamino)-2-methylpropyl)phenoxy)nicotinamide CHEMBL251176 BDBM50224031
6-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-N-(1-(4- (methylsulfonyl)phenyl) piperidin-4- yl)nicotinamide US9663496, Compound 421 BDBM328283
6-(4-(4-cyano-2-methoxyphenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-methoxypropyl)nicotinamide BDBM413021 US10407409, Example 231
6-(4-(4-cyano-2-methoxyphenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(4-methoxybutyl)nicotinamide BDBM413062 US10407409, Example 238
6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-morpholinopropyl)nicotinamide BDBM413130 US10407409, Example 104
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-((1r,4r)-4-methoxycyclohexyl)nicotinamide BDBM413010 US10407409, Example 229
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-((1r,4r)-4-methoxycyclohexyl)nicotinamide US10407409, Example 228 BDBM413006
6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(4-methoxybutan-2-yl)nicotinamide BDBM413125 US10407409, Example 176
6-(4-(4-methoxybenzoyl) piperidine-1-carbonyl)- N-(1-(4- (methylsulfonyl)benzyl) piperidin-4- yl)nicotinamide US9663496, Compound 215 BDBM328077
6-(4-carbamoylpiperidin-1-yl)-5-chloro-N-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-yl)nicotinamide CHEMBL462874 BDBM50248580
6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)-N-(3-hydroxypropyl)nicotinamide BDBM413101 US10407409, Example 26
BDBM186091 US9670142, A141 6-(7-fluoro-1H-indol-5-yl)-4,N-dimethyl-N-((1R,3S)-3-propionylamino-cyclopentyl)-nicotinamide
BDBM186116 US9670142, A146 6-(4-fluoro-1H-indol-5-yl)-4,N-dimethyl-N-((1R,3S)-3-propionylamino-cyclopentyl)-nicotinamide
BDBM187543 US9670193, 21 (R)-N-(1-(benzyl(methyl)amino)propan-2-yl)-6-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinamide
BDBM328083 N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(4- (methylsulfonyl) benzoyl)piperidine-1- carbonyl)nicotinamide US9663496, Compound 221
BDBM328258 N-(1-(4- fluorobenzyl)piperidin- 4-yl)-6-(4-(4- (methylsulfonyl) phenoxy)piperidine-1- carbonyl)nicotinamide US9663496, Compound 396
BDBM328259 N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(4- (methylsulfonyl) phenoxy)piperidine-1- carbonyl)nicotinamide US9663496, Compound 397
BDBM328349 N-(6-(4- acetylphenoxy)pyridin- 3-yl)-6-(4-(4- (methylsulfonyl) phenyl)piperazine-1- carbonyl)nicotinamide US9663496, Compound 487
BDBM392799 US10301297, Example 62 US11345695, Example 62 2-(4-phenoxyphenyl)-6-(4-(vinylsulfonyl)piperazin-1-yl)nicotinamide US11840513, Example 62
BDBM407068 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-4- (isopropyl- amino)-N-(oxetan-3- yl)nicotinamide US10336762, Compound 7
BDBM407097 US10336762, Compound 36 (S)-6-(3-cyanopyrrolo[1,2-b] pyridazin- 7-yl)-4-(isopropylamino)-N- (tetrahydrofuran-3-yl) nicotinamide
BDBM407102 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-(3- hydroxy-3-methylbutyl)-4- (isopropylamino) nicotinamide US10336762, Compound 41
BDBM407146 US10336762, Compound 85 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-4-(isopropyl- amino)-N-(3- (methylsulfonyl)propyl) nicotinamide
BDBM407152 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-(2-(1- hydroxycyclobutyl) ethyl)-4-(isopropylamino) nicotinamide US10336762, Compound 91
BDBM407252 US10336762, Compound 193 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-((1R,3S)- 3-hydroxycyclohexyl)-4- (isopropylamino) nicotinamide
BDBM407509 US10336762, Compound 451 N-(cyanomethyl)-6-(3- cyanopyrrolo[1,2-b] pyridazin-7-yl)-4- ((4-(methylcarbamoyl) phenyl)amino) nicotinamide
BDBM413031 (S)—N-(sec-butyl)-6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinamide US10407409, Example 87
BDBM413061 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-((1r,4r)-4-hydroxycyclohexyl)nicotinamide US10407409, Example 165
BDBM413095 6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)-N-(2-hydroxyethyl)nicotinamide US10407409, Example 25
BDBM413135 6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)-N-(3-morpholinopropyl)nicotinamide US10407409, Example 32
BDBM438540 US10618903, Example 169 N-(3-cyano-3-methylbutyl)-6-(6-cyanopyrazolo[1,5-a]pyrimidin-3-yl)-4-(isopropylamino)nicotinamide
BDBM50218682 CHEMBL243575 N-[2-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-benzo[b]thiophen-7-yl]-6-cyclopropylamino-nicotinamide
BDBM50224024 CHEMBL251177 6-(4-(2-((S)-2-hydroxy-3-(3-isobutyl-2-oxoindolin-4-yloxy)propylamino)-2-methylpropyl)phenoxy)nicotinamide
BDBM50224025 CHEMBL404626 6-(4-(2-((S)-2-hydroxy-3-(3-methyl-2-oxoindolin-4-yloxy)propylamino)-2-methylpropyl)phenoxy)nicotinamide
BDBM50248581 CHEMBL516993 5-chloro-N-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-yl)-6-(4-sulfamoylpiperidin-1-yl)nicotinamide
BDBM50275885 CHEMBL471414 6-(2-acetyl-2,8-diazaspiro[4.5]decan-8-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
BDBM50275887 N-(2-amino-5-(thiophen-2-yl)phenyl)-6-(2-(methylsulfonyl)-2,8-diazaspiro[4.5]decan-8-yl)nicotinamide CHEMBL470582
BDBM50275984 CHEMBL472442 6-(7-acetyl-2,7-diazaspiro[4.4]nonan-2-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
BDBM50275985 6-(2-acetyl-2,7-diazaspiro[3.5]nonan-7-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide CHEMBL472443
BDBM50275986 6-(2-acetyl-2,7-diazaspiro[4.5]decan-7-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide CHEMBL471399
BDBM50276027 N-(2-amino-5-(thiophen-2-yl)phenyl)-6-(1-hydroxy-8-azaspiro[4.5]decan-8-yl)nicotinamide CHEMBL470148
BDBM50337238 CHEMBL1681870 (S)-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)-3-methylpiperazin-1-yl)-N-(cyclohexylmethyl)nicotinamide
BDBM50337261 CHEMBL1681834 (S)-5-chloro-N-methyl-6-(3-methyl-4-(1-(trifluoromethyl)piperidin-4-yl)piperazin-1-yl)nicotinamide
BDBM526955 US11186579, Example 20 5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- yl)-N-(4-fluorophenyl)-2- (trifluoromethyl)nicotinamide
BDBM610033 US9701664, Example 13 N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)-6-(thiazol-4-ylmethoxy)nicotinamide
CHEMBL210847 BDBM50188647 5-chloro-N-methyl-6-(4-(6-(trifluoromethyl)-1H-benzo[d]-imidazol-2-yl)piperazin-1-yl)nicotinamide
CHEMBL2372977 N-{(S)-2-Methyl-1-[2-(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-pyrrolidine-1-carbonyl]-propyl}-nicotinamide BDBM50058377
CHEMBL284498 N-{(S)-1-[(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butylcarbamoyl]-2-cyclohexyl-ethyl}-nicotinamide BDBM50077730
CHEMBL469514 BDBM50276028 N-(2-amino-5-(thiophen-2-yl)phenyl)-6-(1-oxo-2,8-diazaspiro[4.5]decan-8-yl)nicotinamide
CHEMBL486152 BDBM50275363 N-(2-amino-5-(thiophen-2-yl)phenyl)-6-(2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)nicotinamide
N-((cis)-4-(4- cyanophenoxy) cyclohexyl)-6-(4-(3- (cyclopropane- carboxamido)phenoxy) piperidine-1- carbonyl)nicotinamide US9663496, Compound 434 BDBM328296
N-(1-(3,5- difluorobenzyl)piperidin- 4-yl)-6-(4-(4- (methylsulfonyl) phenoxy)piperidine-1- carbonyl)nicotinamide BDBM328098 US9663496, Compound 236
N-(1-(3-methoxybenzyl) piperidin-4-yl)-6-(4-(4- (methylsulfonyl) phenoxy)piperidine-1- carbonyl)nicotinamide US9663496, Compound 238 BDBM328100
N-(1-(4- fluorobenzyl)piperidin- 4-yl)-6-(4-(4- (methylsulfonyl) benzoyl)piperidine-1- carbonyl)nicotinamide BDBM328084 US9663496, Compound 222
N-(1-(4-methoxybenzyl) piperidin-4-yl)-6-(4-(4- (methylsulfonyl) benzoyl)piperidine-1- carbonyl)nicotinamide BDBM328085 US9663496, Compound 223
N-(2-acetamidothiazol- 4-yl)-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-4- (isopropylamino)nicotinamide US10336762, Compound 493 BDBM407551
N-(2-amino-5-(thiophen-2-yl)phenyl)-6-(1-oxo-8-azaspiro[4.5]decan-8-yl)nicotinamide BDBM50276026 CHEMBL470147
N-(2-amino-5-(thiophen-2-yl)phenyl)-6-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)nicotinamide CHEMBL513027 BDBM50276076
N-(2-amino-5-(thiophen-2-yl)phenyl)-6-(3-oxo-2,8-diazaspiro[4.5]decan-8-yl)nicotinamide CHEMBL511984 BDBM50276075
N-(2-amino-5-(thiophen-2-yl)phenyl)-6-(4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)nicotinamide BDBM50276077 CHEMBL469950
N-(3-ethoxypropyl)-6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)nicotinamide BDBM413013 US10407409, Example 12
N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)-6-((3-iodophenyl)amino)nicotinamide US9701664, Example 38 BDBM610065
N-(6-(4- acetylphenoxy)pyridin- 3-yl)-6-(4-(4- (isopropylsulfonyl) phenyl)piperazine-1- carbonyl)nicotinamide US9663496, Compound 489 BDBM328351
N-(6-(4- acetylphenoxy)pyridin- 3-yl)-6-(4-(4- (methylsulfonyl) phenoxy)piperidine-1- carbonyl)nicotinamide BDBM328347 US9663496, Compound 485
N-(6-(4- fluorophenoxy)pyridin- 3-yl)-6-(4-(4- (methylsulfonyl) benzoyl)piperidine-1- carbonyl)nicotinamide BDBM328086 US9663496, Compound 224
N-(6-(4- fluorophenoxy)pyridin- 3-yl)-6-(4-(4- (methylsulfonyl) phenoxy)piperidine-1- carbonyl)nicotinamide BDBM328097 US9663496, Compound 235
US10130633, Example 187 6-(3,5-difluorophenyl)-N-[3-{[2- (morpholin-4- yl)propanoyl]amino}-4- (trifluoromethoxy)phenyl] nicotinamide BDBM300617 BDBM300633
US10227331, Example 335 BDBM368148 2-Amino-5-(4-((2-aminoethyl)sulfonyl)-3-sulfamoyl-2-(2H-tetrazol-5-yl)phenyl)nicotinamide
US10336762, Compound 190 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-((1S,3R)- 3-hydroxycyclohexyl)-4- (isopropylamino) nicotinamide BDBM407249
US10336762, Compound 192 BDBM407251 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-((1R,3R)- 3-hydroxycyclohexyl)- 4-(isopropylamino) nicotinamide
US10336762, Compound 491 BDBM407549 N-(5-acetamidopyridin-3- yl)-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-4- (isopropylamino) nicotinamide
US10336762, Compound 71 BDBM407132 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-(1,1- dioxidothietan-3-yl)-4- (isopropylamino) nicotinamide
US10336762, Compound 88 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-4-(isopropyl- amino)-N-(2- (methylsulfonamido)ethyl) nicotinamide BDBM407149
US10407409, Example 169 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-((1s,2s)-2-methylcyclopropyl)nicotinamide BDBM413085
US10407409, Example 227 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-((1s,4s)-4-methoxycyclohexyl)nicotinamide BDBM413000
US10407409, Example 28 BDBM413112 6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)-N-(4-hydroxybutyl)nicotinamide
US10407409, Example 300 6-(4-(4-cyano-2-cyclopropylphenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-methoxypropyl)nicotinamide BDBM413001
US10407409, Example 86 (S)-6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(tetrahydrofuran-3-yl)nicotinamide BDBM413025
US10407409, Example 93 BDBM413066 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(1-cyclopropylpiperidin-4-yl)nicotinamide
US10618903, Example 11 BDBM438383 6-(6-chloropyrazolo[1,5-a]pyrimidin-3-yl)-4-(isopropylamino)-N-((1R,4R)-4-methoxycyclohexyl)nicotinamide
US10618903, Example 20 6-(6-chloropyrazolo[1,5-a]pyrimidin-3-yl)-N-(3-fluoro-3-methylbutyl)-4-(isopropylamino)nicotinamide BDBM438392
US11241428, Example 29 BDBM535878 N-(3-amino-6-(thiophen-2-yl)pyridin-2-yl)-6-(4-methylpiperazin-1-yl)nicotinamide
US11345695, Example 28 US11840513, Example 28 US9951056, Example 28 BDBM389653 6-(4-acryloylpiperazin-1-yl)-2-(4-(cyclohexyloxy)phenyl)nicotinamide
US11352322, Compound 97 BDBM556460 N-hydroxy-6-(2-(4-(((2-phenylcyclopropyl)amino)methyl)piperidin-1-yl)ethoxy)nicotinamide TFA Salt
US20240425482, Example 10 BDBM708538 N-methyl-5-(3-(2- methyl-5-((3- (trifluoromethyl)phenyl) carbamoyl)phenyl)pyrrolidin- 1-yl)nicotinamide
US9663496, Compound 237 N-(1-(4-methoxybenzyl) piperidin-4-yl)-6-(4-(4- (methylsulfonyl) phenoxy)piperidine-1- carbonyl)nicotinamide BDBM328099
US9663496, Compound 370 BDBM328232 N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(4- (dimethylamino) phenoxy)piperidine-1- carbonyl)nicotinamide
US9670193, 46 (R)-N-(1-(benzyl(methyl)amino)propan-2-yl)-6-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinamide BDBM188075
US9701664, Example 25 BDBM610050 N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)-6-(pyridin-2-ylmethoxy)nicotinamide
US9708253, 94 N-(4-((4-fluorophenyl)sulfonyl)-4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-1-methylcyclohexyl)nicotinamide BDBM261435
rac-N-((2R,4R)-4-(4-fluorophenylsulfonyl)-2-methyl-4-(4-(perfluoropropan-2-yl)phenyl)cyclohexyl)nicotinamide US9708253, 122 BDBM261463