Target (5)
Compound (919)
Article Title (4)
Article Author (12)
Assay (46)
Cincinelli, R; Musso, L; Merlini, L; Giannini, G; Vesci, L; Milazzo, FM; Carenini, N; Perego, P; Penco, S; Artali, R; Zunino, F; Pisano, C; Dallavalle, S 7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors. Bioorg Med Chem 22: 1089 -103 (2014) McDonnell, ME; Zhang, SP; Nasser, N; Dubin, AE; Dax, SL 7-Hydroxynaphthalen-1-yl-urea and -amide antagonists of human vanilloid receptor 1. Bioorg Med Chem Lett 14: 531 -4 (2003) Penthala, NR; Shoeib, A; Dachavaram, SS; Cabanlong, CV; Yang, J; Zhan, CG; Prather, PL; Crooks, PA 7-Azaindolequinuclidinones (7-AIQD): A novel class of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands. Bioorg Med Chem Lett 30: (2020) Faust, R; Garratt, PJ; Trujillo Pérez, MA; Piccio, VJ; Madsen, C; Stenstrøm, A; Frølund, B; Davidson, K; Teh, MT; Sugden, D 7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: effect of substituents on potency and binding affinity. Bioorg Med Chem 15: 4543 -51 (2007)
Uriz-Huarte, A; Date, A; Ang, H; Ali, S; Brady, HJM; Fuchter, MJ Bioorg Med Chem Lett 30: (2020) Wu, T; Nagle, A; Kuhen, K; Gagaring, K; Borboa, R; Francek, C; Chen, Z; Plouffe, D; Goh, A; Lakshminarayana, SB; Wu, J; Ang, HQ; Zeng, P; Kang, ML; Tan, W; Tan, M; Ye, N; Lin, X; Caldwell, C; Ek, J; Skolnik, S; Liu, F; Wang, J; Chang, J; Li, C; Hollenbeck, T; Tuntland, T; Isbell, J; Fischli, C; Brun, R; Rottmann, M; Dartois, V; Keller, T; Diagana, T; Winzeler, E; Glynne, R; Tully, DC; Chatterjee, AK J Med Chem 54: 5116 -30 (2011) Brak, K; Kerr, ID; Barrett, KT; Fuchi, N; Debnath, M; Ang, K; Engel, JC; McKerrow, JH; Doyle, PS; Brinen, LS; Ellman, JA J Med Chem 53: 1763 -73 (2010) Watts, KR; Ratnam, J; Ang, KH; Tenney, K; Compton, JE; McKerrow, J; Crews, P Bioorg Med Chem 18: 2566 -74 (2010) Hu, JF; Schetz, JA; Kelly, M; Peng, JN; Ang, KK; Flotow, H; Leong, CY; Ng, SB; Buss, AD; Wilkins, SP; Hamann, MT J Nat Prod 65: 476 -80 (2002) Ang, MJ; Yong, GH; Poulsen, A; Then, SW; Li, Z; Joy, J; Hill, J; Chia, CS Eur J Med Chem 68: 72 -80 (2013) Huang, C; Liew, SS; Lin, GR; Poulsen, A; Ang, MJY; Chia, BCS; Chew, SY; Kwek, ZP; Wee, JLK; Ong, EH; Retna, P; Baburajendran, N; Li, R; Yu, W; Koh-Stenta, X; Ngo, A; Manesh, S; Fulwood, J; Ke, Z; Chung, HH; Sepramaniam, S; Chew, XH; Dinie, N; Lee, MA; Chew, YS; Low, CB; Pendharkar, V; Manoharan, V; Vuddagiri, S; Sangthongpitag, K; Joy, J; Matter, A; Hill, J; Keller, TH; Foo, K ACS Med Chem Lett 10: 978 -984 (2019) Vankadara, S; Dawson, MD; Fong, JY; Oh, QY; Ang, QA; Liu, B; Chang, HY; Koh, J; Koh, X; Tan, QW; Joy, J; Chia, CSB ACS Med Chem Lett 13: 1345 -1350 (2022) Yang, H; Chennamaneni, LR; Ho, MWT; Ang, SH; Tan, ESW; Jeyaraj, DA; Yeap, YS; Liu, B; Ong, EH; Joy, JK; Wee, JLK; Kwek, P; Retna, P; Dinie, N; Nguyen, TTH; Tai, SJ; Manoharan, V; Pendharkar, V; Low, CB; Chew, YS; Vuddagiri, S; Sangthongpitag, K; Choong, ML; Lee, MA; Kannan, S; Verma, CS; Poulsen, A; Lim, S; Chuah, C; Ong, TS; Hill, J; Matter, A; Nacro, K J Med Chem 61: 4348 -4369 (2018) Patil, NA; Hughes, RA; Rosengren, KJ; Kocan, M; Ang, SY; Tailhades, J; Separovic, F; Summers, RJ; Grosse, J; Wade, JD; Bathgate, RA; Hossain, MA J Med Chem 59: 2118 -25 (2016) Sang, Z; Qiang, X; Li, Y; Yuan, W; Liu, Q; Shi, Y; Ang, W; Luo, Y; Tan, Z; Deng, Y Eur J Med Chem 94: 348 -66 (2015) Taft, BR; Yokokawa, F; Kirrane, T; Mata, AC; Huang, R; Blaquiere, N; Waldron, G; Zou, B; Simon, O; Vankadara, S; Chan, WL; Ding, M; Sim, S; Straimer, J; Guiguemde, A; Lakshminarayana, SB; Jain, JP; Bodenreider, C; Thompson, C; Lanshoeft, C; Shu, W; Fang, E; Qumber, J; Chan, K; Pei, L; Chen, YL; Schulz, H; Lim, J; Abas, SN; Ang, X; Liu, Y; Angulo-Barturen, I; Jiménez-Díaz, MB; Gamo, FJ; Crespo-Fernandez, B; Rosenthal, PJ; Cooper, RA; Tumwebaze, P; Aguiar, ACC; Campo, B; Campbell, S; Wagner, J; Diagana, TT; Sarko, C J Med Chem 65: 3798 -3813 (2022)
ChEMBL_885935 (CHEMBL2215697) Inhibition of ANG ChEMBL_799451 (CHEMBL1942259) Inhibition of PrCP-mediated conversion of Ang3 to Ang(2-7) in mouse plasma ChEMBL_35261 (CHEMBL648567) Displacement of [125I]- Ang II from type 1 Angiotensin II receptor ChEBML_36929 Binding affinity against AT-1 receptor from rabbit aorta using [125I]-Sar1-Ile8-Ang II without BSA ChEBML_36930 Inhibition of [125I]-Sar1-Ile8-Ang II binding to Angiotensin II receptor type 1 from rabbit aorta ChEMBL_36779 (CHEMBL650300) Dissociation constant for [125 I] Ang binding to type 1 Angiotensin II receptor of bovine adrenocortical membranes ChEMBL_1857648 (CHEMBL4358377) Displacement of [125I]Ang II from AT1 receptor in rat liver membranes ChEMBL_457557 (CHEMBL922757) Displacement of [125I]Ang 2 from AT1 receptor in rat liver membranes ChEMBL_34976 (CHEMBL649504) Inhibitory concentration against specific binding of [125 I]Ang II to rat uterine membranes (Angiotensin II receptor, type 1) ChEMBL_35101 (CHEMBL649304) Inhibitory concentration against specific binding of [125 I]Ang II to rat uterine membranes (Angiotensin II receptor, type 1) ChEMBL_2099984 (CHEMBL4808380) Binding affinity to Galphaq/11 (unknown origin) expressed in HEK293 cells cotransfected with AT1R/Galphaq-RLuc8/ Ggamma2-venus/Gbeta1 assessed as inhibition of Ang-II induced-BRET signal preincubated for 1 hr followed by Ang-II addition by BRET assay ChEBML_195752 In vitro inhibition of human renin by radio-immuno assay of angiotensin I (ANG I) ChEBML_35434 Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomes ChEMBL_35416 (CHEMBL643590) Inhibitory concentration against Angiotensin II receptor type 2 with [125I]-[Sar1,Ile8]Ang II ChEBML_35284 Inhibition of [125I]-Sar1-Ile8-Ang II binding to rat midbrain Angiotensin II receptor type 2 ChEMBL_195752 (CHEMBL801603) In vitro inhibition of human renin by radio-immuno assay of angiotensin I (ANG I) ChEMBL_303241 (CHEMBL827206) Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometrium ChEMBL_303611 (CHEMBL829700) Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptor ChEMBL_303706 (CHEMBL829041) Displacement of [125I]-Ang II from pig uterus myometrium angiotensin II type 2 (AT2) receptor ChEMBL_306794 (CHEMBL832379) Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptor ChEMBL_34956 (CHEMBL647799) Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomes ChEMBL_35417 (CHEMBL643591) Inhibition of [125I]-[Sar1,Ile8]Ang II binding at rat angiotensin II (type 2) receptor. ChEMBL_34943 (CHEMBL647786) In vitro binding affinity at rat liver Angiotensin II receptor, type 1 was determined based on displacement of [125I]-Ang II ChEMBL_35277 (CHEMBL647776) Binding affinity for Angiotensin II receptor type 2 using [125I]- Ang II in pig uterus myometrium ChEMBL_34974 (CHEMBL649503) Inhibitory concentration against [125 I]Ang II binding to rat pituitary membranes Angiotensin II receptor type 1 without 0.2% bovine serum albumin ChEMBL_832555 (CHEMBL2067441) Displacement of 125[I-Sar1-Ile8]ANG II from human AT1 receptor expressed in HEK293 membranes after 1 hr by gamma counting ChEMBL_34953 (CHEMBL647796) Compound was evaluated in a radioligand binding assay to displace [125I]-Ang II from Angiotensin II receptor, type 1 in rat liver membranes ChEMBL_35262 (CHEMBL648568) The compound was tested for the ability to displace 50% of totally specifically bound [125I]- Ang II from Angiotensin II receptor, type 1 site ChEMBL_35278 (CHEMBL648317) Binding affinity at Angiotensin II receptor, type 2 in pig uterus myometrial membranes by [125I]-Ang II displacement. ChEMBL_802198 (CHEMBL1949356) Displacement of [125I]Sar1 Ile8-Ang 2 from angiotensin 2 AT1 receptor after 180 mins by gamma counting ChEMBL_802199 (CHEMBL1949357) Displacement of [125I]Sar1 Ile8-Ang 2 from angiotensin 2 AT2 receptor after 180 mins by gamma counting ChEBML_35285 Binding affinity against Angiotensin II receptor type 2 from rat mid brain using [125I]-Sar1-Ile8-Ang II without BSA ChEMBL_1461999 (CHEMBL3396449) Displacement of [125I]-Ang II from AT1 receptor in rat liver membranes after 2 hrs by gamma-counting method ChEMBL_34975 (CHEMBL884036) Inhibitory concentration against specific binding of [125 I]Ang II to rat pituitary membranes (Angiotensin II receptor, type 1) in presence of 0.2% bovine serum albumin ChEMBL_1857650 (CHEMBL4358379) Displacement of [125I]Ang II from AT1 receptor in rat SMC membranes incubated for 60 mins by gamma counting method ChEMBL_910062 (CHEMBL3055782) Displacement of [125I]-SI-Ang-2 from AT1 receptor in Rattus norvegicus Sprague-Dawley (rat) liver membranes after 2 hr ChEMBL_910066 (CHEMBL3057677) Displacement of [125I]-SI-Ang-2 from AT1 receptor in Rattus norvegicus Sprague-Dawley (rat) liver membranes after 2 hr ChEMBL_35275 (CHEMBL648580) Binding affinity towards Angiotensin II receptor, type 2 was measured through displacement of [125I]-Ang II in pig uterus myometrial membranes ChEMBL_35276 (CHEMBL648581) Inhibitory concentration against towards Angiotensin II receptor, type 2 was measured through displacement of [125I]-Ang II in pig uterus myometrial membranes ChEMBL_35435 (CHEMBL643795) Compound was tested for the inhibition of angiotensin II AT2 receptor by displacement of [125I]- Ang II to rat adrenal cortical microsomes ChEMBL_35423 (CHEMBL643597) The compound was tested for the ability to displace 50% of totally specifically bound [125I]- Ang II from Angiotensin II receptor, type 2 ChEMBL_321028 (CHEMBL883660) Binding affinity for angiotensin II receptor, type 1 in rat liver membrane using [125I]-Ang II as radioligand, in pH 7.4 Tris-HCl buffer for 2 hr at 25 degree C ChEMBL_1566203 (CHEMBL3788344) Displacement of [125I]-Ang II from Angiotensin 2 type-1A receptor in rat vascular smooth muscle cells after 150 mins by gamma counting method In Vitro Enzyme Inhibition Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I generated during the incubation was measured by radioimmunoassay. ChEMBL_321033 (CHEMBL883665) Binding affinity for angiotensin II receptor, type 2 in pig uterus myometrium using [125I]-Ang II as radioligand, in pH 7.4 Tris-HCl buffer for 1.5 hr at 25 degree C In Vitro Renin Inhibition Assay In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensin I (ANG I) produced was measured in triplicate in the radioimmunoassay.
Ang(1-7) BDBM85556
Ang(1-7) D-Ala7 BDBM85554
Ang(2-7) BDBM85543
Ang(3-7) BDBM85553
BDBM747659 US12325697, Compound ANG-1
Ang IV Nor1 BDBM85558
Ang(3-10) BDBM85548
Ang(3-11) BDBM85544
Ang(3-5) BDBM85545
Ang(3-6) BDBM85547
Ang(3-9) BDBM85546
Ang(4-8) BDBM85551
BDBM85542 Divalinal Ang IV
Ang II Thr8, Sar1 BDBM85559
BDBM85552 Ang IV D-Val1
BDBM85555 Ang II Ile8, Sar1
Ang III CAS_12687-51-3 BDBM85557
BDBM50156178 CHEMBL216331 c[Hcy3,5]Ang II
CHEMBL424755 [4-NH2-Phe6] Ang II BDBM50208102
CHEMBL261120 BDBM85550 cid_123814 Ang IV CAS_12676-15-2
US12358931, Example 1-7 US10072026, Example 1-7 US10947254, Example 1-7 US11780852, Example 1-7 BDBM277413
BDBM212837 US9278960, 1-7 US9636337, 1-7
BDBM277642 US12358931, Example 7-1 US10072026, Example 7-1 US11780852, Example 7-1
US10485803, Example 1-7 US11110095, Example 1-7 US10028960, Example 1-7 BDBM279824
MLS002638032 7-aminonaphthalen-1-ol cid_40116 BDBM83187 7-amino-1-naphthol 7-azanylnaphthalen-1-ol SMR001547532 7-amino-1-naphthalenol
US8697868, 1(7) US8697868, 7 BDBM120069
BDBM271191 US10975091, Example 7(1) US10059720, Example 7(1)
BDBM405559 US10351547, Compound 1-7 US10597377, Compound 1-7
US20230279020, Example 7-1 US10633389, Example 7-1 BDBM439607
2-[4-chloro-7-(cyclopentylsulfamoyl)isoquinolin-1-yl]guanidine 1-guanidino-7-sulfonamidoisoquinoline 7 BDBM16133
US11492354, Example 7, Peak 1 BDBM459449 US10752635, Example 7, Peak 1
US12291534, Compound C-7-1 BDBM568382 US11420975, Compound C-7-1
US9006249, Example 7-1 US8993631, 19 BDBM153116 US9603819, Example 7-1
BDBM538033 US11248006, Compound 7-1-1
BDBM147501 US8962608, 7-1
BDBM182235 US9145391, 7-1
BDBM194950 US9670211, 7-1 
BDBM237854 US9394282, 7-1
BDBM252980 US9469608, 7-1
BDBM257396 US9493441, 1-7
BDBM300292 US9593110, 7-1
BDBM33306 rhodanine, 1-7
BDBM360668 US9828381, 1-7
BDBM389142 US9951026, 1-7
US8742110, 1-7 BDBM123158
US8846000, 1-7 BDBM135591
US8975265, 1-7 BDBM149495
US9035059, 1-7 BDBM159605
US9145391, 1-7 BDBM182041
US9284317, 1-7 BDBM213795
US9447029, 1-7 BDBM247254
US9505786, 7-1 BDBM258369
US9688645, 1-7 BDBM173900
US9688645, 7-1 BDBM173926
US9884828, 1-7 BDBM282566
US9926318, 1-7 BDBM380489
US9926330, 1-7 BDBM380547
2-(7-sulfamoylisoquinolin-1-yl)guanidine 1-guanidino-7-sulfonamidoisoquinoline 4 BDBM16130
US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [106] US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [116] BDBM110053
BDBM277159 US10072003, Example 7-2 US10072003, Example 7-1
US10647665, Example 1-7 BDBM441818 US10851050, Example I-7
2-[7-(phenylsulfamoyl)isoquinolin-1-yl]guanidine BDBM16131 1-guanidino-7-sulfonamidoisoquinoline 5
US10300056, Example 7 BDBM391722 US10888561, Example 7 N-[(2R)-1-({(2S)-3-(1-
BDBM391394 US9957265, 1-62 US9957265, 1-7
7-[5-Methyl-2-(1-pyrrolidinyl)imidazo[1,5-b]pyridazin-7-yl]-1-phenyl-1-heptanone BDBM3383 Imidazopyridazine 26 7-[5-methyl-2-(pyrrolidin-1-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one
1-(7-Methoxy-naphthalen-1-yl)-piperazine CHEMBL300824 4-(7-Methoxy-naphthalen-1-yl)-piperazin-1-ium BDBM50018459
7-(2-Chloro-5-methylimidazo[1,5-b]pyridazin-7-yl)-1-phenyl-1-heptanone BDBM3365 7-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}-1-phenylheptan-1-one Imidazopyridazine 15c
1-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]-1-propanone 1-[4-(7-chloroquinolin-4-yl)piperazino]propan-1-one BDBM87326 1-[4-(7-chloranylquinolin-4-yl)piperazin-1-yl]propan-1-one SMR000459715 1-[4-(7-chloro-4-quinolyl)piperazino]propan-1-one MLS000860931 1-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propan-1-one cid_2823727
7-chloro-4-piperazino-quinoline SMR000076122 7-chloro-4-piperazin-1-ylquinoline BDBM56192 cid_738389 7-chloranyl-4-piperazin-1-yl-quinoline 7-chloro-4-(1-piperazinyl)quinoline MLS000049580
US9999619, Example 364 US10675284, Example 7 US11130767, # 7 US11406640, Comp. No. 1 US10519163, Example 7 US12268667, Compound 4 US10065963, Compound 7 US10875847, Compound INCB39110 US10336759, # 7 US11136326, Example 7 US11992490, Compound 1 US20240058343, Compound 1 US20240307353, Compound 4 US9732097, Example 7 US11324749, Comp. No. 1 BDBM246868 US10053465, 7 US11084822, Example 7 US11957661, Compound 4 US10125150, Example 7 US11304949, Compound 1 US11596632, Comp. No. 1 US12226418, Example 7 US10479803, Example 7 US11918581, Compound 1 US11285140, Example 364 {1-{1-[3-Fluoro-2- (trifluoromethyl) isonicotinoyl] piperidin-4- yl}-3-[4-(7H- pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1- yl]azetidin-3- yl}acetonitrile
BDBM155098 US9000182, 7, isomer 1
BDBM155135 US9000184, 7, isomer 1
BDBM155150 US9000185, 7, isomer 1
BDBM284934 US10023583, Example 7(1)
BDBM392068 US10301272, Example 7/1
BDBM408656 US10376504, Example 1-7
BDBM409964 US10370337, Example 1-7
BDBM419663 US10464918, Compound 1-7
BDBM435151 US10584134, Example 1-7
BDBM487150 US10952995, Compound 1-7
BDBM506813 US11046652, Example 1-7
BDBM548310 WO2022093856, Example 1-7
BDBM570060 US11427581, Compound 1-7
BDBM609067 US11702418, Example 1-7
BDBM616050 US20230271964, Example 1-7
BDBM658647 US20240083917, Compound 7-1
BDBM706673 US20240383922, Example 7-1
BDBM86001 [leu13]pMOT(1-7)
CHEMBL2205203 BDBM50401302 US8492392, 1-7
OFQ/N (1-7) BDBM85820
US11053242, Compound 7-1 BDBM516523
US11168102, Example 1-7. BDBM524882
US11345701, Compound 7-1 BDBM556282
US11365192, Example 1-7 BDBM558102
US20240308995, Example 1-7 BDBM696927
US20250066290, Example 1/7 BDBM724007
US8598345, Table 1-7 BDBM107221
US9388149, 7 (Diastereoisomer 1) BDBM236808
WO2022098806, Compound 1-7 BDBM548611
WO2022098807, Example 1-7 BDBM552455
2-(4-chloro-7-sulfamoylisoquinolin-1-yl)guanidine 1-guanidino-7-sulfonamidoisoquinoline 6 BDBM16132
2-[7-oxo-7-(3-phenyl-1-pyrrolidinyl)heptyl]isoindole-1,3-dione MLS000120963 2-[7-oxo-7-(3-phenylpyrrolidin-1-yl)heptyl]isoindole-1,3-dione SMR000118340 2-[7-Oxo-7-(3-phenyl-pyrrolidin-1-yl)-heptyl]-isoindole-1,3-dione 2-[7-keto-7-(3-phenylpyrrolidino)heptyl]isoindoline-1,3-quinone 2-[7-oxidanylidene-7-(3-phenylpyrrolidin-1-yl)heptyl]isoindole-1,3-dione BDBM62892 cid_3148600
(S)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol S-(-)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (S)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol BDBM50016774 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol CHEMBL41436
7-(2-Methoxy-5-methylimidazo[1,5-b]pyridazin-7-y1)-1-phenyl-1-heptanone Hydrochloride BDBM3378 7-{2-methoxy-5-methylimidazo[1,5-a]pyridazin-7-yl}-1-phenylheptan-1-one Imidazopyridazine 19
BDBM16134 2-[4-chloro-7-(pyrrolidine-1-sulfonyl)isoquinolin-1-yl]guanidine 1-guanidino-7-sulfonamidoisoquinoline 8
1-(7-chloro-4-quinolinyl)-4-piperidinecarboxamide 1-(7-chloranylquinolin-4-yl)piperidine-4-carboxamide SMR000343665 BDBM63677 cid_2451505 MLS000770157 1-(7-chloro-4-quinolyl)isonipecotamide 1-(7-chloroquinolin-4-yl)piperidine-4-carboxamide
BDBM3379 Imidazopyridazine 20 7-[5-Methyl-2-(methylthio)imidazo[1,5-b]pyridazin-7-y1]-1-phenyl-1-heptanone 7-[5-methyl-2-(methylsulfanyl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one
US9730939, Example 7 US10646492, Example 7 US9707233, 7 1-{1-[5-Chloro-3-(1-isobutylazetidin-3-yl)-2-methoxy-4-methylphenyl]ethyl}-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine US10092570, Example 7 US11433071, Example 7 US10376513, Example 7 US9932341, Example 7 BDBM255796
BDBM415407 Intermediate 1-1-4 US10428063, Example 7
BDBM110063 US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [116]
BDBM3374 Imidazopyridazine 17a 7-{2-chloroimidazo[1,5-a]pyridazin-7-yl}-1-phenylheptan-1-one
BDBM50072985 CHEMBL26879 1-(1,2,3,4-tetrahydroisoquinolin-7-yl)ethanone 1-(1,2,3,4-Tetrahydro-isoquinolin-7-yl)-ethanone
CHEMBL447481 1-(7-Methyl-naphthalen-2-yl)-ethanone 1-(7-methylnaphthalen-2-yl)ethanone BDBM50159242
CHEMBL45987 BDBM50090531 7-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octahydro-indolizin-7-ol
US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [117] BDBM110064
US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [118] BDBM110065
US8609678, 4-(1-(4-fluorophenyl)-1-methoxyethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [120] BDBM110067
7-[2-(1H-Imidazol-l-yl)-5-methylimidazo[1,5-b]pyridazin-7-yl]-1-phenyl-1-heptanone BDBM3386 7-[2-(1H-imidazol-1-yl)-5-methylimidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one Imidazopyridazine 33
BDBM16136 2-{4-chloro-7-[(4-methylpiperazine-1-)sulfonyl]isoquinolin-1-yl}guanidine 1-guanidino-7-sulfonamidoisoquinoline 10
BDBM6646 3-(7-hydroxynaphthalen-1-yl)-1-phenylurea Diarylurea deriv. 1a N-(7-Hydroxy-1-naphthyl)-N -phenylurea
CHEMBL1258200 BDBM50327619 7-fluoro-6-(3-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)propoxy)isoindolin-1-one
CHEMBL1258313 7-fluoro-6-(4-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)butoxy)isoindolin-1-one BDBM50327577
(3S,5S)-7-Methyl-1-oxa-7- BDBM598107 US11612606, Compound 467a
1H-indazol-7-amine, 1 1H-Indazol-7-amine BDBM50271275 CHEMBL463676
BDBM490778 US10968242, Example 7 Peak 2 US10968242, Example 7 Peak 1
BDBM542473 US11274095, Example 7-Enantiomer-2 US11274095, Example 7-Enantiomer-1
BDBM598109 US11612606, Compound 467c (3S,5R)-7-Methyl-1-oxa-7-
US8609678, 4-(diphenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [1] BDBM109949
7-(2-Amino-5-methylimidazo[1,5-b]pyridazin-7-yl)-l-phenyl-1-heptanone Imidazopyridazine 24 7-{2-amino-5-methylimidazo[1,5-a]pyridazin-7-yl}-1-phenylheptan-1-one BDBM3380
US9145391, 1-6 US9145391, 1-7 US9145391, 1-9 BDBM182040
SMR000540549 (2R,3R)-2-[7-[2-(hydroxymethyl)-1-piperidinyl]-7-oxoheptyl]-3-[(E,3S)-3-hydroxyoct-1-enyl]-1-cyclopentanone (2R,3R)-2-[7-[2-(hydroxymethyl)piperidin-1-yl]-7-oxoheptyl]-3-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentan-1-one (2R,3R)-2-[7-[2-(hydroxymethyl)piperidin-1-yl]-7-oxidanylidene-heptyl]-3-[(E,3S)-3-oxidanyloct-1-enyl]cyclopentan-1-one cid_16397324 MLS001213429 (2R,3R)-3-[(E,3S)-3-hydroxyoct-1-enyl]-2-[7-keto-7-(2-methylolpiperidino)heptyl]cyclopentanone BDBM97139
MLS000113626 BDBM66024 1-azepanecarboxylic acid (7-chloro-4-quinolinyl) ester cid_2928644 (7-chloranylquinolin-4-yl) azepane-1-carboxylate azepane-1-carboxylic acid (7-chloro-4-quinolyl) ester SMR000109522 (7-chloroquinolin-4-yl) azepane-1-carboxylate
cid_2836642 4-(azepan-1-yl)-7-nitro-benzofurazan 7-(1-azepanyl)-4-nitro-2,1,3-benzoxadiazole SMR000516457 MLS001209776 4-Azepan-1-yl-7-nitro-benzo[1,2,5]oxadiazole 7-(azepan-1-yl)-4-nitro-2,1,3-benzoxadiazole BDBM66126
1-(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl)-ethanone 1-((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl)-ethanone CHEMBL87348 BDBM50030025
1-(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl)-ethanone BDBM50030004 1-((S)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl)-ethanone CHEMBL87195
US10501451, Example 7, P-2 US10501451, Example 7, P-1 BDBM423277 US10954225, Example 7,P-2
1-(m-trifluorophenyl)piperazine, 7 BDBM29560
7-Hydroxy-1-tetralone (5) BDBM166645
BDBM147112 US8957075, Table 1 Compound 7
BDBM154639 US8999957, Table 1, Compound 7
BDBM182741 US9145412, Table 1, Compound 7
BDBM185641 US9161922, Table 1, Compound 7
BDBM190239 US9174999, Table 1, Compound 7
BDBM221714 US9314468, Table 7, Compound 1
BDBM303464 US10138226, Example 2-7-1
BDBM36608 Rapamycin C-7, analog 1
BDBM542077 US11274090, Example 7 Isomer 1
BDBM574844 US11459315, Example 7 (isomer 1)
BDBM578755 US11479550, Example 7-1(2)
BDBM642074 US11845730, Example 7-peak-1
BDBM699135 US20240327425, Compound I-7-1
BDBM84671 1-Subsituted 1H-imidazole, 7
CHEMBL5200095 BDBM50602435 US11919896, Compound 1-7
Piperazin-1-ium analog, 7 BDBM86555
US11053226, Example 1-7 BDBM50517187 CHEMBL4464335
US11248006, Compound 3-7-1 BDBM538018
US11414384, Example 7 Isomer 1 BDBM563702
US8865686, Table 1, Compound 7 BDBM136695
US9011882, Table 1, Compound 7 BDBM155514
US9085571, Table 1, Compound 7 BDBM171359
US9211296, Table 7, Compd: 1 BDBM196131
US9249087, Table 1 , Compound 7 BDBM218230
US9284322, Table 7, Compound 1 BDBM221045
BDBM110066 US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)-N-methylbenzamide [119]
CHEMBL298720 7-(1H-imidazol-1-ylmethyl)isoquinoline 7-[(Imidazol-1-yl)methyl]isoquinoline BDBM10041 isoquinoline 56
US8609678, 4-(1-(4-fluorophenyl)-1-methoxyethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)-N-methylbenzamide [121] BDBM110068
7-(dimethylamino)-4-methoxy-1-methyl-2-quinolinone BDBM51484 MLS000036158 cid_660402 7-(dimethylamino)-4-methoxy-1-methyl-quinolin-2-one 7-(dimethylamino)-4-methoxy-1-methyl-carbostyril 7-(dimethylamino)-4-methoxy-1-methylquinolin-2-one SMR000034657
7-methoxy-1-methyl-2-phenyl-4-quinolinone BDBM32704 7-methoxy-1-methyl-2-phenyl-4(1H)-quinolinone MLS000549198 SMR000113846 cid_253834 7-methoxy-1-methyl-2-phenylquinolin-4-one 7-methoxy-1-methyl-2-phenyl-quinolin-4-one 7-methoxy-1-methyl-2-phenyl-4-quinolone
MLS001163133 1-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]-2,2-dimethyl-1-propanone 1-[4-(7-chloranylquinolin-4-yl)piperazin-1-yl]-2,2-dimethyl-propan-1-one SMR000499445 1-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]-2,2-dimethylpropan-1-one cid_6473691 BDBM75838 7-chloro-4-[4-(2,2-dimethylpropanoyl)-1-piperazinyl]quinoline 1-[4-(7-chloro-4-quinolyl)piperazino]-2,2-dimethyl-propan-1-one
cid_755673 7-oxidanyl-2,3,4,5-tetrahydro-[1]benzofuro[2,3-c]azepin-1-one BDBM32334 7-hydroxy-2,3,4,5-tetrahydrobenzofuro[2,3-c]azepin-1-one 7-hydroxy-2,3,4,5-tetrahydrobenzofur[2,3-c]azepin-1-one MLS000043346 7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c]azepin-1-one 7-hydroxy-2,3,4,5-tetrahydro-[1]benzofuro[2,3-c]azepin-1-one SMR000019965
BDBM409774 US10370336, Example 1-14 US10370336, Example 1-7
US11612596, Example 1. US10213421, Example 1 US8742115, 7 BDBM123068
4-(4-Fluorophenyl)-7-methylquinoline-2-carboxamide BDBM329011 US9663506, Example 1-7
CHEMBL545097 7-Dipropylamino-7-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride BDBM50011263
Ethylumbelliferone 7-ethoxycoumarin CHEMBL191528 BDBM50303500 7-ethoxy-2H-1-benzopyran-2-one
rac-6-methyl-7-(naphthalen-1-ylethynyl)octahydroindolizin-7-ol BDBM50328810 CHEMBL1270166
7-phenyl-1-(1H-tetrazol-5-yl)heptan-1-one 7-Phenyl-1-(2H-tetrazol-5-yl)-heptan-1-one BDBM50274982 CHEMBL456450
US11479551, Example 1-7 BDBM578782 US11492351, Example 1-7 4-(aminomethyl)-6-(1-methyl-1H-pyrazol-4-yl)phthalazin-1(2H)- one
2-(tert-Butylamino)-1-(7-ethyl-1-benzofuran-2-yl)ethan-1-ol Bufuralol 2-(tert-Butylamino)-1-(7-ethyl-1-benzofuran-2-yl)ethanol BDBM161976 2-(tert-Butylamino)-1-(7-ethylbenzofuran-2-yl)ethan-1-ol
7-{5-methylimidazo[1,5-a]pyridazin-7-yl}-1-phenylheptan-1-one BDBM3377 7-(5-Methylimidazo[1,5-b]pyridazin-7-yl)-l-phenyl-l-heptanone Hydrochloride Imidazopyridazine 18
CHEMBL14285 CHEMBL1535235 1-Methyl-9H-beta-carbolin-7-ol (harmalol) 1-methyl-9H-pyrido[3,4-b]indol-7-ol BDBM50047009 1-Methyl-9H-beta-carbolin-7-ol
cid_27134136 SMR001994483 7-methoxy-4-(pyrrolidinomethyl)coumarin 7-methoxy-4-(1-pyrrolidinylmethyl)-1-benzopyran-2-one 7-methoxy-4-(pyrrolidin-1-ylmethyl)chromen-2-one MLS003314817 BDBM96167
BDBM82953 6-hydroxy-4-(7-methoxy-1-benzofuran-2-yl)-7-methylchromen-2-one 6-hydroxy-4-(7-methoxy-2-benzofuranyl)-7-methyl-1-benzopyran-2-one cid_7295528 SMR000641647 MLS001167538 4-(7-methoxy-1-benzofuran-2-yl)-7-methyl-6-oxidanyl-chromen-2-one 6-hydroxy-4-(7-methoxybenzofuran-2-yl)-7-methyl-coumarin
7-hydroxy-5-methoxy-phthalide 7-hydroxy-5-methoxy-3H-isobenzofuran-1-one 7-hydroxy-5-methoxy-2-benzofuran-1(3H)-one cid_181107 7-hydroxy-5-methoxy-3H-2-benzofuran-1-one SMR000231833 5-methoxy-7-oxidanyl-3H-2-benzofuran-1-one MLS000704668 BDBM90303
BDBM94866 MLS003171337 9H-Thioxanthen-9-one, 1-[2-(dimethylamino)ethylamino]-7-hydroxy- 1-[2-(dimethylamino)ethylamino]-7-hydroxy-thioxanthen-9-one 1-[2-(dimethylamino)ethylamino]-7-oxidanyl-thioxanthen-9-one cid_341818 1-[2-(dimethylamino)ethylamino]-7-hydroxy-9-thioxanthenone SMR001875238 1-[2-(dimethylamino)ethylamino]-7-hydroxythioxanthen-9-one
BDBM3384 7-[5-methyl-2-(piperidin-1-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one Imidazopyridazine 25
BDBM3395 7-[2-(1H-imidazol-1-yl)-5-methylimidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-ol Imidazopyridazine 38
BDBM6651 N-(7-Hydroxy-1-naphthyl)-N -isopropylurea 1-(7-hydroxynaphthalen-1-yl)-3-propan-2-ylurea Diarylurea deriv. 1f
Diarylurea deriv. 1g BDBM6652 3-cyclopentyl-1-(7-hydroxynaphthalen-1-yl)urea N-Cyclopentyl-N -(7-hydroxy-1-naphthyl)urea
US12331044, Example 121 BDBM749830 7-amino-7-[1-(4-fluorophenyl)- 1H-pyrazol-4-yl]-1-isoxazol-3- ylheptan-1-one
US12331044, Example 122 BDBM749831 7-amino-7-[1-(4-fluorophenyl)- 1H-pyrazol-4-yl]-1-isoxazol-3- ylheptan-1-one
3-methyl-7-(naphthalen-1-ylmethyl)-8-piperazin-1-yl-purine-2,6-dione 3-methyl-7-(naphthalen-1-ylmethyl)-8-piperazin-1-ylpurine-2,6-dione 3-methyl-7-(1-naphthalenylmethyl)-8-(1-piperazinyl)purine-2,6-dione SMR000013529 MLS000034623 3-methyl-7-(1-naphthylmethyl)-8-piperazino-xanthine cid_652803 3-Methyl-7-naphthalen-1-ylmethyl-8-piperazin-1-yl-3,7-dihydro-purine-2,6-dione BDBM73227
3-({4-chloro-1-[(diaminomethylidene)amino]isoquinoline-7-}sulfonamido)propanoic acid BDBM16140 1-guanidino-7-sulfonamidoisoquinoline 14
7-nitro-9H-fluoren-1-amine (7-nitro-9H-fluoren-1-yl)amine cid_47726 MLS002694906 SMR001560821 BDBM91392
BDBM110069 US8609678, 4-(1-hydroxy-1-(pyridin-2-yl)ethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [122]
BDBM110071 US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(1-methoxy-1-(pyridin-2-yl)ethyl)benzamide [124]
BDBM16135 1-guanidino-7-sulfonamidoisoquinoline 9 2-[4-chloro-7-(morpholine-4-sulfonyl)isoquinolin-1-yl]guanidine
BDBM16137 2-({4-chloro-1-[(diaminomethylidene)amino]isoquinoline-7-}sulfonamido)benzoic acid 1-guanidino-7-sulfonamidoisoquinoline 11
BDBM16138 1-guanidino-7-sulfonamidoisoquinoline 12 3-({4-chloro-1-[(diaminomethylidene)amino]isoquinoline-7-}sulfonamido)benzoic acid
BDBM16139 1-guanidino-7-sulfonamidoisoquinoline 13 2-({4-chloro-1-[(diaminomethylidene)amino]isoquinoline-7-}sulfonamido)acetic acid
BDBM50014645 7-Methoxy-1-methyl-isoquinolin-6-ol; methosulfate 7-Methoxy-1-methyl-isoquinolin-6-ol CHEMBL3350471
BDBM50336318 CHEMBL1667936 trans-2-(3-(-4-ethylcyclohexyl)-7-methyl-3aH-inden-1-yl)-1-methyl-7-phenylnaphthalene
Imidazopyridazine 17c BDBM3375 7-{2-chloro-5-ethylimidazo[1,5-a]pyridazin-7-yl}-1-phenylheptan-1-one
US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(2,2,2-trifluoro-1-(4-fluorophenyl)-1-hydroxyethyl)benzamide [147] BDBM110094
US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(2,2,2-trifluoro-1-(4-fluorophenyl)-1-methoxyethyl)benzamide [148] BDBM110095
US9745282, 7 BDBM336313 1-(7-chloro-5-(4- (trifluoromethyl)pyri dine-3-yl)indolin-1- yl)ethanone
BDBM43301 N-(7-hydroxy-1-naphthyl)-4-methoxy-benzenesulfonamide N-(7-hydroxy-1-naphthalenyl)-4-methoxybenzenesulfonamide PCMD-CC-MCM-212 PC-0596529 N-(7-hydroxynaphthalen-1-yl)-4-methoxybenzenesulfonamide 4-methoxy-N-(7-oxidanylnaphthalen-1-yl)benzenesulfonamide cid_16738585
cid_16738579 PCMD-CC-MCM-202 N-(7-hydroxy-1-naphthyl)-2,5-dimethoxy-benzenesulfonamide BDBM43291 N-(7-hydroxynaphthalen-1-yl)-2,5-dimethoxybenzenesulfonamide PC-0596519 N-(7-hydroxy-1-naphthalenyl)-2,5-dimethoxybenzenesulfonamide 2,5-dimethoxy-N-(7-oxidanylnaphthalen-1-yl)benzenesulfonamide
CHEMBL90069 BDBM50169147 2-(2-Amino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionic acid (0.75CF3COOH) Ang(3-4) (S)-2-((S)-2-Amino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionic acid
BDBM50163187 7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one CHEMBL173992 7-Phenyl-1-(5-phenyl-oxazol-2-yl)-heptan-1-one
BDBM50240620 N-(4-Chloro-benzyl)-N-(7-pyrrolidin-1-yl-heptyl)-guanidine CHEMBL80582 1-(4-chlorobenzyl)-1-(7-(pyrrolidin-1-yl)heptyl)guanidine
7-Methoxy-1-methyl-9H-beta-carboline (harmine) CHEMBL269538 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole BDBM50047019 7-Methoxy-1-methyl-9H-beta-carboline 11h HARMINE
cid_2141782 7-Methyl-1-(3-phenoxy-propyl)-1H-indole-2,3-dione 7-methyl-1-(3-phenoxypropyl)indole-2,3-dione 7-methyl-1-(3-phenoxypropyl)isatin MLS000528385 BDBM67163 SMR000120960
1-ethyl-7-methyl-4-[(E)-(1-methyl-2-quinolinylidene)methyl]quinolin-1-ium cid_16193144 1-ethyl-7-methyl-4-[(E)-(1-methyl-2-quinolylidene)methyl]quinolin-1-ium 1-ethyl-7-methyl-4-[(E)-(1-methylquinolin-2-ylidene)methyl]quinolin-1-ium BDBM34911 SMR000306531 MLS000727834 2-[(Z)-(1-ethyl-7-methylquinolin-4(1H)-ylidene)methyl]-1-methylquinolinium
(S)-7-amino-1-(isoxazol-3-yl)-7-(4-(7-methoxyquinolin-6-yl)-1H-imidazol-2-yl)heptan-1-one BDBM749743 US12331044, Example 34
(S)-7-amino-7-(4-(7-methoxyquinolin-6-yl)-1H-imidazol-2-yl)-1-(oxazol-2-yl)heptan-1-one BDBM749732 US12331044, Example 23
3-(3,5-dimethyl-4- isoxazolyl)-7-((3-fluoro-1- azetidinyl)carbonyl)-9- (methylsulfonyl)-9H- carbazole-1-carboxamide BDBM243263 US10196387, Example 7 US10053454, Example 7
BDBM70988 4-(1-piperidinyl)-2,1,3-benzoxadiazol-7-amine 4-piperidin-1-yl-2,1,3-benzoxadiazol-7-amine cid_1095028 MLS000764894 SMR000290499 (7-piperidinobenzofurazan-4-yl)amine
7-bromo-3-(2-hydroxyethyl)isocoumarin 7-bromo-3-(2-hydroxyethyl)-2-benzopyran-1-one BDBM91285 SMR001216474 7-bromanyl-3-(2-hydroxyethyl)isochromen-1-one 7-bromo-3-(2-hydroxyethyl)isochromen-1-one cid_25058368 MLS001308090
N-((1S)-1-cyclohexyl- 2-((7-(4-methyl-2- oxoimidazolidin-1-yl)- 7-(methylcarbamoyl)- 6,7,8,9-tetrahydro-5H- benzo[7]annulen-2- yl)amino)-2-oxoethyl)- 1-methyl-1H-pyrazole- 5-carboxamide BDBM740136 US20250154138, Example 7
MLS001178777 cid_1208324 SMR000476358 7-chloro-1-(4-methoxyphenyl)-3-nitroquinolin-4-one 7-chloro-3-nitro-1-(4-methoxyphenyl)-4(1H)-quinolinone 7-chloro-1-(4-methoxyphenyl)-3-nitro-4-quinolone BDBM63932 7-chloro-1-(4-methoxyphenyl)-3-nitro-4-quinolinone 7-chloranyl-1-(4-methoxyphenyl)-3-nitro-quinolin-4-one
1-benzyl-3-(7-hydroxynaphthalen-1-yl)urea BDBM6650 CHEMBL139989 N-Benzyl-N -(7-hydroxy-1-naphthyl)urea Diarylurea deriv. 1e
BDBM3385 7-[5-methyl-2-(1H-pyrrol-1-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one Imidazopyridazine 28
BDBM3387 7-[5-methyl-2-(1H-pyrazol-1-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one Imidazopyridazine 27
3-(fluoromethyl)-7-(propane-1-sulfonyl)-1,2,3,4-tetrahydroisoquinoline BDBM13037 7-sulfonyl-THIQ 27
7-(butane-1-sulfonyl)-3-(fluoromethyl)-1,2,3,4-tetrahydroisoquinoline BDBM13038 7-sulfonyl-THIQ 28
BDBM50026544 CHEMBL97917 7-Phenyl-7-pyridin-3-yl-hept-6-en-1-ol
ethyl 7-((1-(4-cyano-3-fluorophenyl)pyrrolidin-3- US20240166651, Example 7 BDBM676766
US9890156, Example 7 US10738048, Example 7 BDBM357703 US11667635, Example 7 US11014923, Example 7 US10214528, Example 7 N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(1-methyl-1H-pyrazol-3-yl)-2-oxo-1,2,3,4-tetrahydropyrido[4,3-d]pyrimidin-7-yl)methyl)acrylamide
7-chloro-4-hydroxy-1-oxido-3-phenylimino-2-quinoxalin-1-iumcarbonitrile 7-chloro-4-hydroxy-1-oxido-3-phenylimino-quinoxalin-1-ium-2-carbonitrile cid_392857 SMR001566149 7-chloro-4-hydroxy-1-oxido-3-phenyliminoquinoxalin-1-ium-2-carbonitrile 2-Quinoxalinecarbonitrile , 7-chloro-3-(phenylamino)-, 1,4-dioxide BDBM96285 7-chloranyl-1-oxidanidyl-4-oxidanyl-3-phenylimino-quinoxalin-1-ium-2-carbonitrile MLS002702539
cyclopentanecarboxylic acid [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxo-2-benzopyran-7-yl] ester [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] cyclopentanecarboxylate CMLD003315 BDBM52888 MLS000438845 [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxoisochromen-7-yl] cyclopentanecarboxylate cid_16745662 cyclopentanecarboxylic acid [6,8-diketo-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-isochromen-7-yl] ester SMR000452614
(+/-)-(R)-7-Methoxy-1-tetralol CHEMBL206379 BDBM50183618
(+/-)-(R)-7-Nitro-1-tetralol CHEMBL381338 BDBM50183595
BDBM236806 US9388149, 6 US9388149, 7 (Diastereoisomer 1)
BDBM260049 US9522881, 7'c-1 (L95M52)
BDBM50183602 (+)-(S)-7-Nitro-1-tetralol CHEMBL378390
CHEMBL219367 BDBM50200997 1-[7-(triphenylmethoxy)heptyl]thymine
CHEMBL381981 BDBM50183608 (+)-(S)-7-Methoxy-1-tetralol
CHEMBL61032 1-Benzofuran-7-yl-piperazine BDBM50035042
Compound 1-14 BDBM469508 US11072585, Example 7
US11912737, Example 7. BDBM655561 US11912737, Example 1
US20250115576, Example 7 BDBM716112 US12209085, Example 1
US9522881, 7'a-1 (L89M52) BDBM260046
2-(1-Hydroxy-1-methyl-ethyl)-7-phenyl-7-pyridin-3-yl-hept-6-enoic acid BDBM50026532 CHEMBL98901
2-(1-Methyl-9H-beta-carbolin-7-yloxy)-ethanol 7-(2-Hydroxyethyloxy)-1-methyl-beta-carboline BDBM50333417 CHEMBL14355
3-({4-chloro-1-[(diaminomethylidene)amino]isoquinoline-7-}sulfonamido)-2,2-dimethylpropanoic acid BDBM16141 1-guanidino-7-sulfonamidoisoquinoline 15
7-methyl-1-(2-phenoxyethyl)indole-2,3-dione 7-methyl-1-(2-phenoxyethyl)isatin MLS000624518 SMR000323457 BDBM47864 cid_2145491
BDBM110107 US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(3-oxo-1-phenyl-1,3-dihydroisobenzofuran-1-yl)benzamide [160]
BDBM50180298 7-methoxy-N-(4-(4-(7-methoxyisoquinolin-1-yl)piperazin-1-yl)butyl)benzofuran-2-carboxamide CHEMBL201027
BDBM6653 N-(7-Hydroxy-1-naphthyl)-2-phenylacetamide Diarylurea deriv. 13 N-(7-hydroxynaphthalen-1-yl)-2-phenylacetamide
Imidazopyridazine 22 BDBM3381 7-[5-methyl-2-(methylamino)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one
US8609678, 4-(1-hydroxy-1-(pyridin-2-yl)ethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)-N-methylbenzamide [123] BDBM110070
US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(1-methoxy-1-(pyridin-2-yl)ethyl)-N-methylbenzamide [125] BDBM110072
BDBM24628 5-hydroxynaphthalene-1-sulfonamide, 7 5-hydroxynaphthalene-1-sulfonamide
BDBM464491 US11072585, Example 1 Compound 1-7 US11072585, Example 30
BDBM50204493 CHEMBL220125 1-(oxazol-2-yl)-7-phenylheptan-1-one
BDBM50344350 CHEMBL1779670 1-(7-hydroxynaphthalen-1-yl)-3-m-tolylurea
(+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol BDBM50020719 CHEMBL14791 (-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol (+/-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol
(+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol CHEMBL14708 (-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol BDBM50020718 (+/-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol
MLS003171335 BDBM97044 1-[2-(dimethylamino)ethylamino]-7-methoxy-thioxanthen-9-one cid_341816 1-[2-(dimethylamino)ethylamino]-7-methoxythioxanthen-9-one 1-[2-(dimethylamino)ethylamino]-7-methoxy-9-thioxanthenone SMR001875236
4-[1-[(7-chloroquinolin-4-yl)amino]ethyl]benzenesulfonamide 4-[1-[(7-chloro-4-quinolyl)amino]ethyl]benzenesulfonamide MLS001233728 4-[1-[(7-chloranylquinolin-4-yl)amino]ethyl]benzenesulfonamide 4-[1-[(7-chloro-4-quinolinyl)amino]ethyl]benzenesulfonamide BDBM96774 SMR000595175 cid_17390528
BDBM83428 [1-(4-aminophenyl)ethylideneamino]-(7-chloro-4-quinolyl)amine N-[1-(4-aminophenyl)ethylideneamino]-7-chloroquinolin-4-amine MLS001242760 N-[1-(4-aminophenyl)ethylideneamino]-7-chloro-4-quinolinamine cid_3807606 N-[1-(4-aminophenyl)ethylideneamino]-7-chloranyl-quinolin-4-amine SMR000841513
SMR000526308 7-[3-(1-imidazolyl)propylamino]-2,3-dimethyl-9-xanthenone 7-(3-imidazol-1-ylpropylamino)-2,3-dimethylxanthen-9-one BDBM65606 cid_24747878 MLS001144090 7-(3-imidazol-1-ylpropylamino)-2,3-dimethyl-xanthen-9-one 7-(3-imidazol-1-ylpropylamino)-2,3-dimethyl-xanthone
7-Phenyl-1-(4H-1,2,4-triazol-3-yl)-heptan-1-one 7-phenyl-1-(4H-1,2,4-triazol-3-yl)heptan-1-one CHEMBL499698 BDBM50262525
BDBM50163186 1-(5-(oxazol-2-yl)oxazol-2-yl)-7-phenylheptan-1-one 1-[2,5'']Bioxazolyl-2''-yl-7-phenyl-heptan-1-one CHEMBL176122
BDBM50087746 GLP-1(7-37) Glucagon like peptide-1(GLP-1) CHEMBL428139
BDBM700964 1-(7-nitroindolin-1-yl)ethan-1-on US20240343694, Example 94
BDBM700965 1-(7-aminoindolin-1-yl)ethan-1- on US20240343694, Example 95
5-bromo-7-(piperidin-1-ylmethyl)quinolin-8-ol 5-bromanyl-7-(piperidin-1-ylmethyl)quinolin-8-ol BDBM34601 5-bromo-7-(1-piperidinylmethyl)-8-quinolinol 5-bromo-7-(piperidinomethyl)quinolin-8-ol MLS000090125 cid_678099 SMR000024743
cid_4838551 4-(imidazol-1-ylmethyl)-7-methyl-6-oxidanyl-chromen-2-one 6-hydroxy-4-(imidazol-1-ylmethyl)-7-methyl-coumarin BDBM69815 6-hydroxy-4-(1-imidazolylmethyl)-7-methyl-1-benzopyran-2-one 6-hydroxy-4-(imidazol-1-ylmethyl)-7-methylchromen-2-one MLS001214371 SMR000543712
cid_679749 7-Methoxy-3-(1-methyl-1H-benzoimidazol-2-yl)-chromen-2-one BDBM51619 7-methoxy-3-(1-methylbenzimidazol-2-yl)chromen-2-one SMR000116061 7-methoxy-3-(1-methyl-2-benzimidazolyl)-1-benzopyran-2-one 7-methoxy-3-(1-methylbenzimidazol-2-yl)coumarin MLS000525587
US11548890, Compound I-7 BDBM500350 4-(7-methoxy- 1H-indol-3- yl-)-7-[[5-(4- methylpiperazin- 1-yl)-2- pyridyl]amino]-2,3- dihydropyrrolo [3,4-c]pyridin-1-one US11021481, Compound I-7 US11078201, Compound I-7
7-(diethylamino)-3-(1-methylbenzimidazol-2-yl)chromen-2-one MLS000106045 7-(diethylamino)-3-(1-methyl-2-benzimidazolyl)-1-benzopyran-2-one cid_100335 SMR000103016 7-(diethylamino)-3-(1-methylbenzimidazol-2-yl)coumarin BDBM79817
BDBM592661 US11572374, Example 1-84 7-bromo-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-1-oxo-1,2- dihydro-3-isoquinolinecarboxamide
BDBM592752 N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-N-methyl-1- (2,3,5-trichlorophenyl)-D-prolinamide US11572374, Example 7-13-1
BDBM749736 US12331044, Example 27 (S)-7-amino-7-(5-(7-methoxy-2-methylquinolin-6-yl)oxazol-2-yl)-1-(oxazol-2-yl)heptan-1-one
US10676457, Example 7 US9994546, Example 7 BDBM397508 US11155532, Example 7 (1-Benzoyl-3-{4-[(trans-2-phenylcyclopropyl)amino]piperidin-1-yl}azetidin-3-yl)acetonitrile
7-[2-(Dimethylamino)-5-methylimidazo[1,5-b]pyridazin-7-yl]-l-phenyl-l-heptanone Imidazopyridazine 21 BDBM3382 7-[2-(dimethylamino)-5-methylimidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one
CHEMBL14708 (-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol CHEMBL544668 BDBM50011256 (+/-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride (-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride 7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride (+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride
CHEMBL14791 CHEMBL544899 BDBM50011265 (+/-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol (+/-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide (+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide 7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide (-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide
7-hydroxy-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-4-one 7-oxidanyl-3-(1-phenylpyrazol-4-yl)chromen-4-one SMR000298681 BDBM44231 cid_5407918 MLS000689960 7-hydroxy-3-(1-phenyl-4-pyrazolyl)-1-benzopyran-4-one 7-hydroxy-3-(1-phenylpyrazol-4-yl)chromen-4-one 7-hydroxy-3-(1-phenylpyrazol-4-yl)chromone
3-(7-hydroxynaphthalen-1-yl)-1-pyridin-4-ylurea N-(7-Hydroxy-1-naphthyl)-N -pyridin-4-ylurea BDBM6648 Diarylurea deriv. 1c
7-[5-methyl-2-(1H-1,2,4-triazol-1-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one BDBM3388 Imidazopyridazine 29
BDBM3389 Imidazopyridazine 31 7-[5-methyl-2-(1H-1,2,3-triazol-1-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one
N-(7-Hydroxy-1-naphthyl)-N -pyridin-2-ylurea BDBM6654 Diarylurea deriv. 14 3-(7-hydroxynaphthalen-1-yl)-1-pyridin-2-ylurea
N-(7-Hydroxy-1-naphthyl)-N -pyridin-3-ylurea BDBM6647 Diarylurea deriv. 1b 3-(7-hydroxynaphthalen-1-yl)-1-pyridin-3-ylurea
N-(3-acetylphenyl)-3-(1-methylpyrazol-4-yl)-1-benzofuran-7-carboxamide N-(3-ethanoylphenyl)-3-(1-methylpyrazol-4-yl)-1-benzofuran-7-carboxamide BDBM95240 N-(3-acetylphenyl)-3-(1-methyl-4-pyrazolyl)-7-benzofurancarboxamide MLS003120506 cid_46948162 N-(3-acetylphenyl)-3-(1-methylpyrazol-4-yl)benzofuran-7-carboxamide SMR001289880
US10421750, Example 7 7-ethyl-5-(1-phenethylpiperidin-4-yl)- 4-oxa-7-azaspiro[2.5]octan-8-one BDBM413875
US10689345, Example 7 N-(1-cyanopyrrolidin-3-yl)-4- phenylthiazole-2-carboxamide US10343992, Example 7 US11066365, Example 7 BDBM404348
(2Z)-2-[(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methylidene]-1-cyclohexanone MLS001013446 (2Z)-2-[(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methylene]cyclohexanone SMR000353402 cid_6535273 BDBM90600 (2Z)-2-[(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methylidene]cyclohexan-1-one
7-[[4-(4-methoxyphenyl)-1-piperazinyl]-oxomethyl]-2-propyl-3H-isoindol-1-one 7-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-2-propyl-3H-isoindol-1-one cid_16193482 7-{[4-(4-methoxyphenyl)piperazin-1-yl]carbonyl}-2-propylisoindolin-1-one 7-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-2-propyl-isoindolin-1-one MLS000730896 7-[4-(4-methoxyphenyl)piperazin-1-yl]carbonyl-2-propyl-3H-isoindol-1-one BDBM63565 SMR000309271
BDBM406053 1-(chroman-4-yl)-3-(1',4- dimethyl-1-phenyl-1H,1'H-3,4'- bipyrazol-5-yl)urea US10889589, EX. # 7 US10351575, Example 7
MLS000767327 4-methyl-7-(3-pyridin-1-ium-1-ylpropoxy)chromen-2-one;bromide BDBM66629 4-methyl-7-(3-pyridin-1-ium-1-ylpropoxy)coumarin;bromide cid_16682426 4-methyl-7-[3-(1-pyridin-1-iumyl)propoxy]-1-benzopyran-2-one;bromide SMR000429658 1-[3-(4-Methyl-2-oxo-2H-chromen-7-yloxy)-propyl]-pyridinium
US10173996, Example 7 BDBM263937 US9714230, 7 2-(3-(2-chlorophenyl)-5-hydroxy- 1H-pyrazol-1-yl)isonicotinic acid US9604961, Example 7 US9908865, Example 7
US11084798, Cpd No 7 US11130759, Cpd. No. 7 7-chloro-5-fluoro-4-(methylamino)-1- phenyl-quinazolin-2(1H)-one BDBM507731 US11046691, Compound 7
SMR000705839 1-[4-(3,4-dihydro-2H-1,5-benzodioxepin-7-ylsulfonyl)-1-piperazinyl]-1-hexanone cid_24686518 1-[4-(3,4-dihydro-2H-1,5-benzodioxepin-7-ylsulfonyl)piperazino]hexan-1-one BDBM70186 MLS001161784 1-[4-(3,4-dihydro-2H-1,5-benzodioxepin-7-ylsulfonyl)piperazin-1-yl]hexan-1-one
7-ethoxy-1,1,2,2,4-pentamethylquinolin-1-ium;iodide MLS000710504 cid_16192939 SMR000280271 BDBM63545 7-ethoxy-1,1,2,2,4-pentamethyl-quinolin-1-ium;iodide
BDBM50011247 CHEMBL541621 S-(-)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide CHEMBL41436
BDBM50022055 1-Phenyl-6-chloro-7-hydroxy-1,2,3,4-tetrahydroisoquinoline CHEMBL446396 6-Chloro-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol
BDBM82801 7-methoxy-1,1,2,2,4-pentamethylquinolin-1-ium;iodide MLS000709959 SMR000287126 7-methoxy-1,1,2,2,4-pentamethyl-quinolin-1-ium;iodide cid_16192935
CHEMBL158984 7-Imidazol-1-ylmethyl-chromen-4-one 7-((1H-imidazol-1-yl)methyl)-4H-chromen-4-one BDBM50097369
CHEMBL513892 BDBM50263150 N-(4,6-dimethyl-1-octylindolin-7-yl)pivalamide N-(4,6-dimethyl-1-octylindolin-7-yl)-2,2-dimethylpropanamide
N-(2-(7-methoxynaphthalen-1-yl)ethyl)benzamide BDBM50037241 N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-benzamide CHEMBL34348
N-[2-(7-sulfamoyl-naphth-1-yl)ethyl]acetamide CHEMBL457763 N-(2-(7-sulfamoylnaphthalen-1-yl)ethyl)acetamide BDBM50342773
1'-(1H-indazole-7-carbonyl)-7-methoxyspiro[chroman-2,4'-piperidin]-4-one BDBM50314922 CHEMBL1089473
7-(prop-2-ene-1-sulfonyl)-1,2,3,4-tetrahydroisoquinoline BDBM13020 7-sulfonyl-THIQ 10 CHEMBL280592
BDBM50023952 CHEMBL3559633 1-{7-Carboxy-7-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-6-enyl}-pyridinium
BDBM50026525 7-(1-Oxy-pyridin-3-yl)-7-phenyl-hept-6-enoic acid CHEMBL317322
BDBM50026546 CHEMBL320158 7-Naphthalen-1-yl-7-pyridin-3-yl-hept-6-enoic acid
BDBM50314923 1'-(1H-indazole-7-carbonyl)-7-phenylspiro[chroman-2,4'-piperidin]-4-one CHEMBL1091217
CHEMBL1090122 1'-(1H-indazole-7-carbonyl)-7-methylspiro[chroman-2,4'-piperidin]-4-one BDBM50314916
CHEMBL1270167 BDBM50328811 rac-6-methyl-7-(2-(naphthalen-1-yl)ethyl)octahydroindolizin-7-ol
CHEMBL237010 BDBM50224051 (-)-N3-(1-(1-adamantyl)ethyl)-7-chloro-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide (+)-N3-(1-(1-adamantyl)ethyl)-7-chloro-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide ((+/-)-N3-(1-(1-adamantyl)ethyl)-7-chloro-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide
MLS001144091 7-[2-(1-hydroxycyclohexyl)ethynyl]-2,3-dimethoxy-9-thioxanthenone BDBM75187 SMR000526319 7-[2-(1-hydroxycyclohexyl)ethynyl]-2,3-dimethoxy-thioxanthen-9-one cid_24747920 7-[2-(1-hydroxycyclohexyl)ethynyl]-2,3-dimethoxythioxanthen-9-one 2,3-dimethoxy-7-[2-(1-oxidanylcyclohexyl)ethynyl]thioxanthen-9-one
ethyl 4-(7-chloranylquinolin-4-yl)piperazine-1-carboxylate ethyl 4-(7-chloroquinolin-4-yl)piperazine-1-carboxylate 4-(7-chloro-4-quinolyl)piperazine-1-carboxylic acid ethyl ester SMR000591939 BDBM75843 4-(7-chloro-4-quinolinyl)-1-piperazinecarboxylic acid ethyl ester cid_7783431 MLS001176740
BDBM408674 US11198691, Example 7 1-({4-[(4-methylpyrazol-1-yl)methyl]phenyl}methyl)-N-{[3- (trifluoromethoxy)phenyl]methyl}-3-(trifluoromethyl)pyrazole-4-carboxamide US10364238, Example 7 US11001578, Example 7 US11084809, Example 7
US10072026, Example 7-7 US12358931, Example 7-7 US11780852, Example 7-7 BDBM277648
1-(4-(pyrrolidin-1-ylmethyl)benzylidene)-2-(7-chloroquinolin-4-yl)hydrazine BDBM50192696 1-(7-chloroquinolin-4-yl)-2-{[4-(pyrrolidin-1-yl)methyl]benzylidene}hydrazine CHEMBL218355 7-chloro-4-{2-[4-(pyrrolidin-1-ylmethyl)benzylidene]diazan-1-iumyl}quinolinium
(S)-7-(benzylamino)-7-(5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl)-1-(oxazol-2-yl)heptan-1-one US12331044, Example 82 BDBM749791
1-((7-chloro-1,2,3,4-tetrahydro-1- naphthalenyl)methyl)-3-((1R,2R,4S)-7- cyano-7-azabicyclo[2.2.1]heptan-2-yl)urea US11572374, Example 23-6 BDBM592895
BDBM749744 (S)-6-(2-(1-amino-7-(isoxazol-3-yl)-7-oxoheptyl)-1H-imidazol-5-yl)-7-methoxy-1-methylquinolin-2(1H)-one US12331044, Example 35
BDBM749786 (S)-6-(2-(1-(ethylamino)-7-(oxazol-2-yl)-7-oxoheptyl)-1H-imidazol-5-yl)-7-methoxy-1-methylquinolin-2(1H)-one US12331044, Example 77
US11572374, Example 1-69 BDBM592646 (4R)-7-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2,3,4,5- tetrahydro-1-benzoxepine-4-carboxamide
US12331044, Example 31 BDBM749740 (S)-7-amino-1-(isoxazol-3-yl)-7-(4-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl)heptan-1-one
SMR000019964 6,8-bis(bromanyl)-7-oxidanyl-2,3,4,5-tetrahydro-[1]benzofuro[2,3-c]azepin-1-one cid_1504045 BDBM68481 MLS000043345 6,8-dibromo-7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c]azepin-1-one 6,8-dibromo-7-hydroxy-2,3,4,5-tetrahydrobenzofur[2,3-c]azepin-1-one 6,8-dibromo-7-hydroxy-2,3,4,5-tetrahydrobenzofuro[2,3-c]azepin-1-one 6,8-dibromo-7-hydroxy-2,3,4,5-tetrahydro-[1]benzofuro[2,3-c]azepin-1-one
BDBM79940 cid_24818804 1-methoxy-7-[2-(2-pyridyl)ethynyl]xanthone MLS001249977 1-methoxy-7-(2-pyridin-2-ylethynyl)xanthen-9-one 1-methoxy-7-[2-(2-pyridinyl)ethynyl]-9-xanthenone SMR000685943
1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one CHEMBL452886 BDBM50261886
1-(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl)-pentan-1-one CHEMBL25913 BDBM50030006
1-Benzyl-1-ethyl-3-(7-hydroxy-naphthalen-1-yl)-urea BDBM50138513 CHEMBL151378
BDBM50138509 1-Benzyl-3-(7-hydroxy-naphthalen-1-yl)-1-methyl-urea CHEMBL262816
BDBM50262244 CHEMBL469198 1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one
CHEMBL1779678 1-(3-(1-hydroxyethyl)phenyl)-3-(7-hydroxynaphthalen-1-yl)urea BDBM50344358
US10947229, Example 1 US11634419, Example 1 BDBM473564 US11702415, Compound 1 US10844057, Example 7
CHEMBL73593 3-(1-Benzyl-piperidin-4-yl)-1-(1,2,3,4-tetrahydro-quinolin-7-yl)-propan-1-one 3-(1-benzylpiperidin-4-yl)-1-(1,2,3,4-tetrahydroquinolin-7-yl)propan-1-one BDBM50039206
7-[5-methyl-2-(4-methyl-1H-imidazol-1-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one Imidazopyridazine 35 BDBM3393
7-[5-methyl-2-(5-methyl-1H-imidazol-1-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one Imidazopyridazine 36 BDBM3392
BDBM3394 7-[5-methyl-2-(2-methyl-1H-imidazol-1-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one Imidazopyridazine 34
BDBM578962 US11479551, Example 7-1 US11492351, Example 7-1 4-(aminomethyl)-6-(5-(pyridin-4-yloxy)pyridin-3- yl)phthalazin-1(2H)-one
US11117874, Example 7 (2S)-N-[(1S)-1-Cyano-2-(3',4'-difluorobiphenyl-4-yl)ethyl]-1,4-oxazepane-2- carboxamide US20230278969, Example 7 US10287258, Example 7 US11655221, Example 7 US11680049, Example 7 US11667615, Example 7 US10669245, Example 7 BDBM385047
(+-)-1-(1-bromoethvI)-2-chloro-3-(trifluoromethyl)benzene BDBM246857 US10053463, 7
1-(2,4-dichlorophenyl)-3-(7-hydroxynaphthalen-1-yl)urea BDBM50344362 CHEMBL1779682
1-(2-(2,3-dihydrobenzofuran-7-yl)-1-phenylethyl)piperazine BDBM50319833 CHEMBL1083707
1-(3-bromophenyl)-3-(7-hydroxynaphthalen-1-yl)urea CHEMBL1779675 BDBM50344355
1-(4-acetyloxazol-2-yl)-7-phenylheptan-1-one BDBM50247139 CHEMBL461543
1-(4-methoxyoxazol-2-yl)-7-phenylheptan-1-one CHEMBL526161 BDBM50247138
1-(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl)-ethanone BDBM50030012 CHEMBL286250
1-(7-Hydroxy-naphthalen-1-yl)-3-phenethyl-urea BDBM50138511 CHEMBL147022
1-(7-hydroxynaphthalen-1-yl)-3-(3-methoxyphenyl)urea BDBM50344352 CHEMBL1779672
1-Di(isopropyl)- phosphinoyl- heptane BDBM562697 US11406649, Code DIPA-1-7
7-Phenyl-1-(pyridazin-3-yl)-heptan-1-one CHEMBL455556 BDBM50262479
BDBM50028738 CHEMBL15166 1-[7-(1H-imidazol-1-yl)heptyl]-1H-imidazole
BDBM50189273 CHEMBL215980 1-(7-bromo-3,4-dihydronaphthalen-1(2H)-ylidene)thiosemicarbazide
BDBM50247035 1-(4-bromooxazol-2-yl)-7-phenylheptan-1-one CHEMBL448688
BDBM50247036 1-(4-chlorooxazol-2-yl)-7-phenylheptan-1-one CHEMBL462432
BDBM50247037 CHEMBL462302 1-(4-iodooxazol-2-yl)-7-phenylheptan-1-one
BDBM50262135 CHEMBL467796 1-(1,3,4-Oxadiazol-2-yl)-7-phenylheptan-1-one
BDBM50262368 CHEMBL468221 7-Phenyl-1-(thiazol-2-yl)-heptan-1-one
BDBM50344351 1-(3-fluorophenyl)-3-(7-hydroxynaphthalen-1-yl)urea CHEMBL1779671
BDBM50344353 CHEMBL1779673 1-(7-hydroxynaphthalen-1-yl)-3-(3-nitrophenyl)urea
BDBM50344354 1-(3-acetylphenyl)-3-(7-hydroxynaphthalen-1-yl)urea CHEMBL1779674
BDBM50344360 CHEMBL1779680 1-(2,6-dichlorophenyl)-3-(7-hydroxynaphthalen-1-yl)urea
BDBM50344361 1-(2,5-dichlorophenyl)-3-(7-hydroxynaphthalen-1-yl)urea CHEMBL1779681
BDBM50344363 1-(3,4-dichlorophenyl)-3-(7-hydroxynaphthalen-1-yl)urea CHEMBL1779683
BDBM50344364 CHEMBL1779684 1-(3,5-dichlorophenyl)-3-(7-hydroxynaphthalen-1-yl)urea
CHEMBL113532 N-[7-(1-Hydroxy-ethyl)-isoquinolin-1-yl]-guanidine BDBM50147408
CHEMBL1779667 1-(2-chlorophenyl)-3-(7-hydroxynaphthalen-1-yl)urea BDBM50344347
CHEMBL1779668 1-(3-chlorophenyl)-3-(7-hydroxynaphthalen-1-yl)urea BDBM50344348
CHEMBL1779669 BDBM50344349 1-(4-chlorophenyl)-3-(7-hydroxynaphthalen-1-yl)urea
CHEMBL373555 1-(5-bromooxazol-2-yl)-7-phenylheptan-1-one BDBM50204475
CHEMBL448922 BDBM50262188 1-(1,2,4-Oxadiazol-5-yl)-7-phenylheptan-1-one
CHEMBL462405 BDBM50247038 1-(4-methyloxazol-2-yl)-7-phenylheptan-1-one
CHEMBL469050 1-(1,2,4-Oxadiazol-3-yl)-7-phenylheptan-1-one BDBM50262305
US20230365541, Compound 7, isomer 1 BDBM636163 US20230365541, Compound 11, isomer 1
US20240010639, Example 7 (S)-6-((1-(Bicyclo[4.2.0]octan-1 BDBM645003
1-(4-(dimethylamino)phenyl)-3-(7-(hydroxyamino)-7-oxoheptyl)urea BDBM50214433 7-[3-(4-dimethylaminophenyl)-ureido]heptanoic acid hydroxyamide CHEMBL227120
7-Phenyl-1-(5-phenyl-[1,3,4]oxadiazol-2-yl)-heptan-1-one BDBM50161526 CHEMBL178115 7-phenyl-1-(5-phenyl-1,3,4-oxadiazol-2-yl)heptan-1-one
US11247992, Example 7 US10717737, Example 7 US10174030, Example 7 US9670210, Example 7 3-[(3-{[(trans-2-Phenylcyclopropyl)amino]methyl}azetidin-1-yl)methyl]benzonitrile BDBM193847
4-[1-[2-(7-chloranylquinolin-4-yl)hydrazinyl]ethylidene]cyclohexa-2,5-dien-1-one 4-[1-[(7-chloro-4-quinolinyl)hydrazo]ethylidene]-1-cyclohexa-2,5-dienone 4-[1-[N'-(7-chloro-4-quinolyl)hydrazino]ethylidene]cyclohexa-2,5-dien-1-one MLS001242770 4-[1-[2-(7-chloroquinolin-4-yl)hydrazinyl]ethylidene]cyclohexa-2,5-dien-1-one cid_5922663 BDBM67688 SMR000841514
cid_6036600 MLS001173902 4-[1-[N'-(7-chloro-4-quinolyl)hydrazino]propylidene]cyclohexa-2,5-dien-1-one 4-[1-[2-(7-chloranylquinolin-4-yl)hydrazinyl]propylidene]cyclohexa-2,5-dien-1-one BDBM54836 4-[1-[2-(7-chloroquinolin-4-yl)hydrazinyl]propylidene]cyclohexa-2,5-dien-1-one SMR000590556 4-[1-[(7-chloro-4-quinolinyl)hydrazo]propylidene]-1-cyclohexa-2,5-dienone
cid_766918 BDBM76382 SMR000115867 1-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-3-phenylpropan-1-one 1-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-3-phenyl-1-propanone 1-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-3-phenyl-propan-1-one MLS000067575 1-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-3-phenyl-propan-1-one
1-(3-methylphenoxy)-3-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)propan-2-ol cid_4830799 MLS000334289 1-(3-methylphenoxy)-3-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)-2-propanol BDBM32861 SMR000249047
US10227346, Example 7 US9920054, Example 7 BDBM189879 US9670201, 7 3-cyano-N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-4-methylbenzamide US10426135, Example 7
7-[(2-chlorophenyl)-pyrrolidino-methyl]quinolin-8-ol 7-[(2-chlorophenyl)-(1-pyrrolidinyl)methyl]-8-quinolinol 7-[(2-chlorophenyl)-pyrrolidin-1-yl-methyl]quinolin-8-ol BDBM64703 SMR000371583 7-[(2-chlorophenyl)-pyrrolidin-1-ylmethyl]quinolin-8-ol cid_5187118 MLS000761483
(S)-N-(1-(5-(7-methoxy-2-methylquinolin-6-yl)oxazol-2-yl)-7-(oxazol-2-yl)-7-oxoheptyl)-1-methylazetidine-3-carboxamide US12331044, Example 100 BDBM749809
3-(7-Chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)-N-(3-(7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)phenyl)benzamide US20250243188, Example 7 BDBM761344
5-(methoxymethyl)-7-(pyrrolidinomethyl)quinolin-8-ol SMR000111795 cid_689261 5-(methoxymethyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol BDBM39073 5-(methoxymethyl)-7-(1-pyrrolidinylmethyl)-8-quinolinol MLS000107426
CHEMBL26606 7-Benzyl-3-isobutyl-1-methyl-3,7-dihydro-purine-2,6-dione BDBM50014255 7-Benzyl-3-isobutyl-1-methyl-3,7-dihydro-purine-2,6-dione(7-benzyl-IBMX)
MLS000094939 cid_3238417 5-(phenylmethoxymethyl)-7-(piperidin-1-ylmethyl)quinolin-8-ol 5-(phenylmethoxymethyl)-7-(1-piperidinylmethyl)-8-quinolinol SMR000030493 BDBM38963 5-(benzoxymethyl)-7-(piperidinomethyl)quinolin-8-ol
MLS000576661 BDBM61857 7-nitro-5-(1-pyrrolidinylmethyl)-8-quinolinol 7-nitro-5-(pyrrolidinomethyl)quinolin-8-ol SMR000197129 cid_690617 7-nitro-5-(pyrrolidin-1-ylmethyl)quinolin-8-ol
US10323037, Example 7 BDBM389990 4-amino-3-(4-phenoxyphenyl)-1- [[(2R)-1-prop-2-enoylpyrrolidin-2- yl]methyl]-6H-pyrrolo[2,3- d]pyridazin-7-one US9951077, 7
US12331044, Example 108 BDBM749817 (S)-N-(7-(isoxazol-3-yl)-1-(5-(7-methoxy-2-methylquinolin-6-yl)oxazol-2-yl)-7-oxoheptyl)-1-methylazetidine-3-carboxamide
US12331044, Example 76 BDBM749785 (S)-7-methoxy-1-methyl-6-(2-(1-(methylamino)-7-(oxazol-2-yl)-7-oxoheptyl)-1H-imidazol-5-yl)quinolin-2(1H)-one
US9815842, Example 7 BDBM355883 (S)-1-(2-fluoro-7-(1-methoxyethyl)pyrazolo[1,5-a]pyrimidin-6-yl)-3-(2-(trifluoromethyl)pyridin-4-yl)urea US10442808, Example 7
3-(1-benzylpiperidin-4-yl)-1-(1-methyl-1,2,3,4-tetrahydroquinolin-7-yl)propan-1-one BDBM50039212 3-(1-Benzyl-piperidin-4-yl)-1-(1-methyl-1,2,3,4-tetrahydro-quinolin-7-yl)-propan-1-one CHEMBL76470
BDBM89013 cid_44142305 3-(1-hydroxycyclohexyl)-7-[2-(3-methyl-4-imidazolyl)ethynyl]-2-benzopyran-1-one 3-(1-hydroxycyclohexyl)-7-[2-(3-methylimidazol-4-yl)ethynyl]isochromen-1-one 3-(1-hydroxycyclohexyl)-7-[2-(3-methylimidazol-4-yl)ethynyl]isocoumarin 7-[2-(3-methylimidazol-4-yl)ethynyl]-3-(1-oxidanylcyclohexyl)isochromen-1-one MLS002402821 SMR001370589
(S)-(1-(7-amino- BDBM683394 US20240217978, Example 47
(S)-(1-(7-amino- BDBM683415 US20240217978, Example 68
(S)-(1-(7-amino- BDBM683416 US20240217978, Example 69
(S)-(1-(7-amino- BDBM683417 US20240217978, Example 70
(S)-(1-(7-amino- BDBM683734 US20240217978, Example 390
(S)-(1-(7-amino- BDBM683735 US20240217978, Example 391
(S)-(1-(7-amino- BDBM683746 US20240217978, Example 402
(S)-(1-(7-amino- US20240217978, Example 283 BDBM683627
1-((7-amino-2- BDBM683476 US20240217978, Example 131
1-((7-amino-2- US20240217978, Example 132 BDBM683477
1-((7-amino-2- US20240217978, Example 133 BDBM683478
1-Amin-5-Naphthol-7-Sulfonic acid BDBM231695
1-azolyl-4-phenyl-2-butanone, 7 BDBM84805
1-methyl-7-nitro-1H-indazole BDBM50240903 CHEMBL354723
7-(Allyloxy)-1-methyl-beta-carboline BDBM50333414 CHEMBL1645544
7-(Isobutyloxy)-1-methyl-beta-carboline BDBM50333415 CHEMBL1645545
7-(Phenethoxy)-1-methyl-beta-carboline CHEMBL1645550 BDBM50333421
7-Thiophosphonomethyl-naphthalene-1-carboxylic acid BDBM50131866 CHEMBL122519
BDBM223979 7-Chloro-N-cyclopentylquinolin-4-amine (1)
BDBM415255 Intermediate 1-10-7 US10428044, Example 362
BDBM415412 US10428063, Example 12 Intermediate 1-2-7
BDBM50029033 7-Phenylamino-naphthalene-1-sulfonic acid anion
BDBM50147427 1-Guanidino-isoquinoline-7-carboxylic acid CHEMBL113114
BDBM50191442 (2'Z)-7-bromo-1-methylindirubin CHEMBL375870
BDBM50333419 7-(Cyclohexylmethoxy)-1-methyl-beta-carboline CHEMBL1645548
BDBM50333420 7-(Benzyloxy)-1-methyl-beta-carboline CHEMBL1645549
BDBM50333428 7-(Ethyloxymorpholine)-1-methyl-beta-carboline CHEMBL1645557
BDBM555711 US11345676, Example 7 US11345676, Compound 1-213
BDBM582898 US10961242, Compound 51 Example 7-1 BDBM489330
BDBM683392 (S)-(1-(7-amino- US20240217978, Example 45
BDBM683628 (S)-(1-(7-amino- US20240217978, Example 284
BDBM683629 (S)-(1-(7-amino- US20240217978, Example 285
BDBM683674 US20240217978, Example 330 (S)-(1-(7-amino-
BDBM683749 (S)-(1-(7-amino- US20240217978, Example 405
BDBM683750 (S)-(1-(7-amino- US20240217978, Example 406
CHEMBL123495 7-Phosphonomethyl-naphthalene-1-carboxylic acid BDBM50131868
CHEMBL210161 (2'Z)-7-iodo-1-methylindirubin BDBM50191413
CHEMBL378787 (2'Z)-7-fluoro-1-methylindirubin BDBM50191416
CHEMBL380241 BDBM50191432 (2'Z)-7-chloro-1-methylindirubin
CHEMBL60803 7-Piperazin-1-yl-1H-indole BDBM50035062
US20240217978, Example 245 BDBM683590 (S)-(1-(7-amino-
US20240217978, Example 322 (S)-(1-(7-amino- BDBM683666
US20240217978, Example 374 BDBM683718 ((S)-1-(7-amino-
US20240217978, Example 389 (S)-(1-(7-amino- BDBM683733
US20240217978, Example 66 (S)-1-(7-amino- BDBM683413
US20240217978, Example 72 BDBM683419 ((S)-1-(7-amino-
[Gly8]GLP-1(7-37)-NH2 CHEMBL526685 BDBM50261507
2-(1-Methyl-piperidin-2-yl)-chroman-7-ol (+-)-2-(1-Methyl-piperidin-2-yl)-chroman-7-ol CHEMBL143572 BDBM50107858
7-hydroxy-7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]heptan-1-one alpha-ketooxazole, 13i BDBM23129
7-{3-[1-(tert-butylamino)-2-cyano-(Z)-1-iminomethylamino]phenyl}-7-(3-pyridyl)-(E)-6-heptenoic acid BDBM50075625 CHEMBL21478
BDBM121285 US8722896, (-)-(3R)-1-(Indol-7-ylmethyl)-N- (9-chloro-2,3,4,5-tetrahydro-1- benzoxepin-7-ylmethyl)-N- isobutylpyrrolidine-3- carboxamide
BDBM121294 US8722896, (-)-(3R)-1-(Indol-7-ylmethyl)-N- (9-chloro-2,3,4,5-tetrahydro-1- benzoxepin-7-ylmethyl)-N- isobutylpiperidine-3- carboxamide
BDBM121310 US8722896, (-)-(3R)-1-(Indolin-7-ylmethyl)- N-(9-chloro-2,3,4,5-tetrahydro- 1-benzoxepin-7-ylmethyl)-N- isobutylpiperidine-3- carboxamide
BDBM3376 7-[2-chloro-5-(propan-2-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one Imidazopyridazine 17d
BDBM413869 7-(4-methoxybenzyl)-5-(1- phenethylpiperidin-4-yl)-4-oxa-7- azaspiro[2.5]octan-8-one US10421750, Example 1
BDBM50342770 N-(2-(7-(methylthio)naphthalen-1-yl)ethyl)acetamide N-[2-(7-methylsulfanyl-naphth-1-yl)ethyl]acetamide CHEMBL456727
CHEMBL141379 (+-)-2-(1-Methyl-pyrrolidin-2-yl)-chroman-7-ol 2-(1-Methyl-pyrrolidin-2-yl)-chroman-7-ol BDBM50107856
CHEMBL1774086 BDBM50343283 7-(4-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)butoxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
CHEMBL456646 N-(2-(7-(methylsulfinyl)naphthalen-1-yl)ethyl)acetamide BDBM50342771 N-[2-(7-methylsulfinyl-naphth-1-yl)ethyl]acetamide
CHEMBL458209 N-[2-(7-methylsulfonyl-naphth-1-yl)ethyl]acetamide N-(2-(7-(methylsulfonyl)naphthalen-1-yl)ethyl)acetamide BDBM50342772
CHEMBL513585 BDBM50244297 cis-1-methyl-7-((4-o-tolylpiperidin-1-yl)methyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol
Ethyl [2-(1-{[(4- Bromophenyl)carbamoyl] amino}propyl)-1H- imidazol-1-yl]acetate US10800744, Number 7 US10301269, Number 7 BDBM391962
N-{2-[7-(methylsulfamoyl)naphthalen-1-yl]ethyl}acetamide CHEMBL1738752 N-[2-(7-methylsulfamoyl-naphth-1-yl)ethyl]acetamide BDBM50342774
US8722896, (-)-(3R)-1-(Indolin-7-ylmethyl)- N-(9-chloro-2,3,4,5-tetrahydro- 1-benzoxepin-7-ylmethyl)-N- isobutylpyrrolidine-3- carboxamide BDBM121304
MLS000860929 cid_2823693 [4-(7-chloranylquinolin-4-yl)piperazin-1-yl]-cyclohexyl-methanone [4-(7-chloroquinolin-4-yl)piperazin-1-yl]-cyclohexylmethanone [4-(7-chloroquinolin-4-yl)piperazino](cyclohexyl)methanone BDBM89370 SMR000459713 [4-(7-chloro-4-quinolinyl)-1-piperazinyl]-cyclohexylmethanone [4-(7-chloro-4-quinolyl)piperazino]-cyclohexyl-methanone
[4-(7-chloro-4-quinolinyl)-1-piperazinyl]-cyclobutylmethanone [4-(7-chloroquinolin-4-yl)piperazino](cyclobutyl)methanone MLS000860928 BDBM75837 cid_2823686 SMR000459712 [4-(7-chloro-4-quinolyl)piperazino]-cyclobutyl-methanone [4-(7-chloranylquinolin-4-yl)piperazin-1-yl]-cyclobutyl-methanone [4-(7-chloroquinolin-4-yl)piperazin-1-yl]-cyclobutylmethanone
BDBM749811 (S)-N-(7-(isoxazol-3-yl)-1-(5-(7-methoxy-1-methyl-2-oxo-1,2-dihydroquinolin-6-yl)-1H-imidazol-2-yl)-7-oxoheptyl)-1-methylazetidine-3-carboxamide US12331044, Example 102
US9783527, Example 102 BDBM344800 1-[2-(1,4-dioxa-7-azaspiro[4.4]non-7-yl)-2-oxoethyl]-3-[1-(2-fluorophenyl)-1H-indazol-4-yl]imidazolidin-2-one 1-[2-(1,4-dioxa-7-
US9783527, Example 212 BDBM344910 1-{2-[(1s,4s)-7- 1-{2-[(1s,4s)-7-azabicyclo[2.2.1]hept-7-yl]-2-oxoethyl}-3-[1-(2-fluorophenyl)-1H-indazol-4-yl]imidazolidin-2-one
1-[(7-chloroquinolin-4-yl)amino]-3-(2,4-dichlorophenyl)thiourea 1-[(7-chloro-4-quinolinyl)amino]-3-(2,4-dichlorophenyl)thiourea 1-[(7-chloro-4-quinolyl)amino]-3-(2,4-dichlorophenyl)thiourea MLS000402395 BDBM50389 cid_2305102 1-[(7-chloranylquinolin-4-yl)amino]-3-(2,4-dichlorophenyl)thiourea SMR000262235
2-(azepan-1-yl)-7-methoxy-4-methylquinoline;oxalic acid SMR000354779 cid_16195960 2-(azepan-1-yl)-7-methoxy-4-methyl-quinoline;ethanedioic acid 2-(azepan-1-yl)-7-methoxy-4-methyl-quinoline;oxalic acid BDBM72595 MLS001018567 2-(1-azepanyl)-7-methoxy-4-methylquinoline;oxalic acid
4-methylthiobenzoic acid S-(7-ketocyclohepta-1,3,5-trien-1-yl) ester cid_917183 S-(7-oxidanylidenecyclohepta-1,3,5-trien-1-yl) 4-methylbenzenecarbothioate BDBM66074 S-(7-oxocyclohepta-1,3,5-trien-1-yl) 4-methylbenzenecarbothioate MLS001173246 4-methylbenzenecarbothioic acid S-(7-oxo-1-cyclohepta-1,3,5-trienyl) ester SMR000539107
7-(azepan-1-ylmethyl)-[1,3]thiazolo[3,2-a]pyrimidin-5-one 7-(azepan-1-ylmethyl)thiazolo[3,2-a]pyrimidin-5-one 7-(1-azepanylmethyl)-5-thiazolo[3,2-a]pyrimidinone cid_2463832 MLS000679440 7-(1-azepanylmethyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one BDBM73601 SMR000297598
7-oxidanyl-3-phenyl-8-(pyrrolidin-1-ylmethyl)chromen-4-one MLS000083054 7-hydroxy-3-phenyl-8-(pyrrolidinomethyl)chromone SMR000044199 7-hydroxy-3-phenyl-8-(pyrrolidin-1-ylmethyl)chromen-4-one 7-hydroxy-3-phenyl-8-(1-pyrrolidinylmethyl)-1-benzopyran-4-one cid_5389711 BDBM48542
7-oxidanyl-4-[[4-(phenylmethyl)piperazin-1-yl]methyl]chromen-2-one MLS001175707 BDBM75209 4-[(4-benzylpiperazino)methyl]-7-hydroxy-coumarin SMR000590787 7-hydroxy-4-[[4-(phenylmethyl)-1-piperazinyl]methyl]-1-benzopyran-2-one cid_5638819 4-[(4-benzylpiperazin-1-yl)methyl]-7-hydroxychromen-2-one
BDBM51494 MLS000036894 7-hydroxy-4-propyl-8-(pyrrolidin-1-ylmethyl)chromen-2-one 7-hydroxy-4-propyl-8-(pyrrolidinomethyl)coumarin cid_5389391 7-hydroxy-4-propyl-8-(1-pyrrolidinylmethyl)-1-benzopyran-2-one 7-oxidanyl-4-propyl-8-(pyrrolidin-1-ylmethyl)chromen-2-one SMR000042448
N-((R)-1-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1]heptane-7- carbonyl)-7-methoxy-1-methyl-1H- benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-7-fluoro-1H- indol-6-yl)ethyl)-3- fluorobicyclo[1.1.1]pentane-1- carboxamide US11878965, Example 144 BDBM646159
SMR000385492 1-[(7-chloranylquinolin-4-yl)amino]-3-(4-ethoxyphenyl)thiourea 1-[(7-chloro-4-quinolinyl)amino]-3-(4-ethoxyphenyl)thiourea BDBM89351 1-[(7-chloro-4-quinolyl)amino]-3-p-phenetyl-thiourea MLS001033099 1-[(7-chloroquinolin-4-yl)amino]-3-(4-ethoxyphenyl)thiourea cid_2393314
1-[2-(dimethylamino)ethylamino]-4-(hydroxymethyl)-7-oxidanyl-xanthen-9-one 9H-Xanthen-9-one, 1-[[2-(dimethylamino)ethyl]amino]- 7-hydroxy-4-(hydroxymethyl)- MLS002702888 1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-methylol-xanthone cid_337396 1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-(hydroxymethyl)xanthen-9-one SMR001566706 1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-(hydroxymethyl)-9-xanthenone BDBM94854
BDBM72888 7-(cyclohexylamino)-1-ethyl-6-fluoranyl-4-oxidanylidene-quinoline-3-carbohydrazide SMR000555818 7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carbohydrazide 7-(cyclohexylamino)-1-ethyl-6-fluoro-4-keto-quinoline-3-carbohydrazide 7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxoquinoline-3-carbohydrazide 7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-3-quinolinecarbohydrazide cid_718467 MLS001196861
4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium cid_42640 7-(4-methylpiperazino)-4-nitro-1-oxido-benzofurazan-1-ium 4-(4-methyl-1-piperazinyl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium BDBM51256 SMR000528763 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxidanidyl-2,1,3-benzoxadiazol-3-ium Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide MLS000756495
Ro 3-4787 2-(tert-butylamino)-1-(7-ethyl-1-benzofuran-2-yl)ethanol 2-(tert-butylamino)-1-(7-ethyl-1-benzofuran-2-yl)ethan-1-ol Bufuralol BDBM21362
US10047097, 7 US11267818, Example 7 BDBM136590 US10774085, Example 7 US8865698, 7 US10005783, 7 US9676783, 7
US9920047, 7 US10414761, Example 7 US9487511, 7 BDBM256628 US10053456, 7 US10968213, Example 7 US9718814, 7
BDBM93557 cid_43795 Benzofurazan, 4-nitro-7-[4-(phenylmethyl)-1-piperazinyl]-, 1-oxide 7-nitro-3-oxidanidyl-4-[4-(phenylmethyl)piperazin-1-yl]-2,1,3-benzoxadiazol-3-ium SMR001830735 4-(4-benzylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium 7-(4-benzylpiperazino)-4-nitro-1-oxido-benzofurazan-1-ium 7-nitro-3-oxido-4-[4-(phenylmethyl)-1-piperazinyl]-2,1,3-benzoxadiazol-3-ium MLS003115152
(R)-7-(4-(1-(4-Chlorophenyl)ethylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide CHEMBL598407 BDBM50307789
(R)-7-(4-(1-(4-Fluorophenyl)ethylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide BDBM50307788 CHEMBL598406
(R)-N-Hydroxy-7-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)heptanamide BDBM50307787 CHEMBL605976
(S)-N-hydroxy-7-(7-methoxy-4-(1-phenylethylamino)quinazolin-6-yloxy)heptanamide BDBM50307786 CHEMBL599218
6-(1H-1,3-benzodiazol-2-yl)-7H-benzo[7]annulen-7-one BDBM5326 benzoannulenone 1
7-Hydroxy-8-piperidin-1-ylmethyl-chromen-2-one BDBM50174559 CHEMBL193416 8-piperidinomethyl-7-hydroxycoumarin
BDBM110115 US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(piperazin-1-yl)pyrimidine-5-carboxamide [168]
BDBM50000610 7-[7-(4-Hydroxy-piperidin-1-yl)-heptyloxy]-2-phenyl-chromen-4-one CHEMBL38952
BDBM50198351 CHEMBL224039 1-(7'-acetyl-6,6'-dihydroxy-2',3'-dihydro-[2,3']bibenzofuranyl-7-yl)-ethanone
BDBM50334737 3-(Naphthalen-1-ylsulfonyl)-N-(piperidin-7-yl)-1H-indazol-7-amine HCl CHEMBL1642860
CHEMBL15101 (7-Chloro-quinolin-4-yl)-(7-piperidin-1-yl-heptyl)-amine; Oxalic acid BDBM50110282
GLP-1(7-36)-NH2 NH2-HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-CONH2 CHEMBL410972 GLP-17-(7-36) derivative BDBM50152769
US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(piperidin-1-yl)pyrimidine-5-carboxamide [187] BDBM110134
(S)-7-isopropoxy-4-(3-morpholinoprop-1-yn-1-yl)-1-((5-oxopyrrolidin-2-yl)methoxy)isoquinoline-6-carboxamide BDBM639185 US20230391748, Compound I-7
(S)-N-(1-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-7-(oxazol-2-yl)-7-oxoheptyl)-1-methylazetidine-3-carboxamide US12331044, Example 1 BDBM749710
34(2,6-dichloro-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)benzoic acid BDBM555278 US11344533, Compound 1-7
BDBM330405 US9725439, 7 1-(4-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-7-methoxyquinazoline-6-ylamino)piperidin-1-yl)prop-2-ene-1-one
BDBM406675 US10336755, Example 7 1-(4-(7-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyridin-5-yl)piperidin-1-yl)prop-2-en-1-one
BDBM50081814 CHEMBL175546 7-Methoxy-naphthalene-2-sulfonic acid [1-(1-amino-isoquinolin-7-ylmethyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-amide
4-(7-benzofuranylazo)-N,N-dimethylaniline 4-(1-benzofuran-7-yldiazenyl)-N,N-dimethylaniline SMR000529112 MLS000756725 4-(1-benzofuran-7-yldiazenyl)-N,N-dimethyl-aniline BDBM76588 [4-(benzofuran-7-ylazo)phenyl]-dimethyl-amine cid_39164
BDBM50719 [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] furan-2-carboxylate 2-furancarboxylic acid [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxo-2-benzopyran-7-yl] ester MLS000438863 [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxoisochromen-7-yl] furan-2-carboxylate cid_16745613 CMLD003318 SMR000452615 furan-2-carboxylic acid [6,8-diketo-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-isochromen-7-yl] ester
CMLD003302 2-thiophenecarboxylic acid [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxo-2-benzopyran-7-yl] ester cid_16759498 [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] thiophene-2-carboxylate [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxoisochromen-7-yl] thiophene-2-carboxylate MLS000438844 BDBM52961 SMR000452616 thiophene-2-carboxylic acid [6,8-diketo-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-isochromen-7-yl] ester
1-methoxy-7-[2-(1-methyl-2-pyrrolidinyl)ethylamino]-9-thioxanthenone MLS001249993 BDBM76140 SMR000685959 cid_24818810 1-methoxy-7-[2-(1-methylpyrrolidin-2-yl)ethylamino]thioxanthen-9-one
BDBM50157136 1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one CHEMBL177356 1-(5-Furan-2-yl-oxazol-2-yl)-7-phenyl-heptan-1-one
BDBM35371 SMR000048561 7-chloro-5-(1-pyrrolidinyl)-2,1,3-benzoxadiazol-4-amine cid_667215 7-chloro-5-pyrrolidin-1-yl-2,1,3-benzoxadiazol-4-amine (7-chloro-5-pyrrolidino-benzofurazan-4-yl)amine 7-chloranyl-5-pyrrolidin-1-yl-2,1,3-benzoxadiazol-4-amine MLS000042514
7-(methyloxy)-2H-chromen-2-one 7-methoxy-2H-1-benzopyran-2-one 7-Methoxycoumarin Herniarin Ayapanin CHEMBL49732 BDBM50303499 Herniarine Methylumbelliferone
BDBM646162 US11878965, Example 147 N-((R)-1-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1]heptane-7- carbonyl)-1-cyclopropyl-7-methoxy- 1H-benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-indol-6- yl)ethyl)-1-methoxycyclopropane-1- carboxamide
CHEMBL339439 cid_386231 7-[(2-hydroxy-1-methyl-2-phenyl-ethyl)amino]quinoline-5,8-quinone 7-[(1-hydroxy-1-phenylpropan-2-yl)amino]quinoline-5,8-dione 7-[(1-oxidanyl-1-phenyl-propan-2-yl)amino]quinoline-5,8-dione BDBM80759 SMR001565859 MLS002702297
MLS000037215 BDBM38572 1,3-dimethyl-8-(4-methyl-1-piperazinyl)-7-(1-naphthalenylmethyl)purine-2,6-dione 1,3-dimethyl-8-(4-methylpiperazino)-7-(1-naphthylmethyl)xanthine cid_663989 SMR000037506 1,3-dimethyl-8-(4-methylpiperazin-1-yl)-7-(naphthalen-1-ylmethyl)purine-2,6-dione
N-((R)-1-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1]heptane-7- carbonyl)-7-methoxy-1-methyl-1H- benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-indol-6- yl)ethyl)-1-methoxycyclobutane-1- carboxamide BDBM646156 US11878965, Example 141
US11878965, Example 142 BDBM646157 N-((R)-1-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1]heptane-7- carbonyl)-7-methoxy-1-methyl-1H- benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-indol-6- yl)ethyl)-1-methoxycyclopropane-1- carboxamide
(S)-N-(1-(5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl)-7-(oxazol-2-yl)-7-oxoheptyl)-1-methylazetidine-3-carboxamide BDBM749808 US12331044, Example 99
(S)-N-(7-(isoxazol-3-yl)-1-(5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl)-7-oxoheptyl)-1-methylazetidine-3-carboxamide BDBM749812 US12331044, Example 103
BDBM203871 7-(3-((3-formylphenoxy)methyl)-1,5-dimethyl-1H-pyrazol-4-yl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid, 7 Mcl-1 inhibitor 7
N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-1-(6-methyl-2- pyridinyl)-7-(trifluoromethyl)-1H-indazole-5- carboxamide US11572374, Example 22-1 BDBM592889
US12331044, Example 84 (S)-7-(5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl)-7-((3-methoxycyclobutyl)amino)-1-(oxazol-2-yl)heptan-1-one BDBM749793
US12331044, Example 85 (S)-7-(5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl)-1-(oxazol-2-yl)-7-(pyrimidin-2-ylamino)heptan-1-one BDBM749794
US12331044, Example 98 (S)-N-(1-(5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl)-7-(oxazol-2-yl)-7-oxoheptyl)-1-methylpiperidine-4-carboxamide BDBM749807
BDBM20412 3-(7-hydroxynaphthalen-1-yl)-1-[3-(methylsulfanyl)phenyl]urea naphthalene deriv., 1
BDBM50189263 CHEMBL212718 1-(7-bromo-3,4-dihydronaphthalen-1-yl)prop-2-en-1-one
BDBM6634 Diarylurea 1 3-(5-chloro-2-methylphenyl)-1-(7-hydroxynaphthalen-1-yl)urea
BDBM683671 (S)-1-(1'-(1-(7-amino-2-(furan-2-yl)- US20240217978, Example 327
(-)7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride CHEMBL43475 CHEMBL544757 (+)7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride 7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride BDBM50011261
CHEMBL340807 7-Methoxy-1-methyl-2,9-dihydro-1H-beta-carboline BDBM50029799 HARMALINE 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole CHEMBL2089157 7-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline
US10227312, Example 7 US10759769, Example 7 N-((1R,2R)-3-(azetidin-1-yl)-1-(4- cyclopropoxy-3-fluorophenyl)-1- hydroxypropan-2-yl)-7-(4- fluorophenyl)-1H- benzo[d][1,2]oxazine-4-carboxamide BDBM367622
US10238658, Example 7 BDBM330265 1-(3-(tert-butyl)-1-(4-methoxyphenyl)-1H- pyrazol-5-yl)-3-(4-((2-(phenylamino) pyrimidin-4-yl)oxy)naphthalen-1-yl)urea US9724347, Example 7 US9993478, Example 7
4-methylumbelliferone cid_5280567 beta-Methylumbelliferone CHEMBL12208 7-Hydroxy-4-methyl-2H-1-benzopyran-2-one BDBM50022178 7-Hydroxy-4-methylcoumarin Imecromone 7-Hydroxy-4-methyl-2H-2-one (1) 7-Hydroxy-4-methyl-2-oxo-3-chromene 4-Methyl-7-hydroxycoumarin 7-hydroxy-4-methyl-2H-chromen-2-one 7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran Coumarin derivative, 3b
1-phenyl-1-cyclopropanecarboxylic acid (5-oxo-7-thiazolo[3,2-a]pyrimidinyl)methyl ester (5-oxo-[1,3]thiazolo[3,2-a]pyrimidin-7-yl)methyl 1-phenylcyclopropane-1-carboxylate BDBM91483 cid_4828948 MLS002155921 1-phenylcyclopropanecarboxylic acid (5-ketothiazolo[3,2-a]pyrimidin-7-yl)methyl ester SMR001238439 (5-oxidanylidene-[1,3]thiazolo[3,2-a]pyrimidin-7-yl)methyl 1-phenylcyclopropane-1-carboxylate
5-nitro-N-[(7-prop-2-enoxy-1-naphthalenyl)methylideneamino]-1-benzothiophene-2-carboxamide N-[(7-allyloxy-1-naphthyl)methyleneamino]-5-nitro-benzothiophene-2-carboxamide N'-{[7-(allyloxy)-1-naphthyl]methylene}-5-nitro-1-benzothiophene-2-carbohydrazide cid_3718011 5-nitro-N-[(7-prop-2-enoxynaphthalen-1-yl)methylideneamino]-1-benzothiophene-2-carboxamide BDBM55507 MLS000327498 SMR000180446
US11351149, Example 7 N-[(2S)-1-({(1 S)-1-Cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}amino)-4,4-dimethyl-1- oxopentan-2-yl]-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide (7) BDBM510055 WO2021250648, Example 7
MLS000683608 1-[1-(7-methoxy-1-benzofuran-2-yl)ethyl]-3-(3-methylphenyl)-1-(3-morpholin-4-ylpropyl)thiourea SMR000311765 1-[1-(7-methoxybenzofuran-2-yl)ethyl]-1-(3-morpholinopropyl)-3-(m-tolyl)thiourea cid_16193316 N-[1-(7-methoxy-1-benzofuran-2-yl)ethyl]-N'-(3-methylphenyl)-N-(3-morpholin-4-ylpropyl)thiourea BDBM73662 1-[1-(7-methoxy-2-benzofuranyl)ethyl]-3-(3-methylphenyl)-1-[3-(4-morpholinyl)propyl]thiourea
N'-(3-ethylphenyl)-N-[1-(7-methoxy-1-benzofuran-2-yl)ethyl]-N-(3-morpholin-4-ylpropyl)thiourea SMR000311761 3-(3-ethylphenyl)-1-[1-(7-methoxybenzofuran-2-yl)ethyl]-1-(3-morpholinopropyl)thiourea BDBM90503 cid_16193315 3-(3-ethylphenyl)-1-[1-(7-methoxy-1-benzofuran-2-yl)ethyl]-1-(3-morpholin-4-ylpropyl)thiourea MLS000683604 3-(3-ethylphenyl)-1-[1-(7-methoxy-2-benzofuranyl)ethyl]-1-[3-(4-morpholinyl)propyl]thiourea
1-acetyl-5-bromo-N-[2-(2-methylpiperidino)ethyl]indoline-7-sulfonamide 1-acetyl-5-bromo-N-[2-(2-methylpiperidin-1-yl)ethyl]-2,3-dihydroindole-7-sulfonamide 1-acetyl-5-bromo-N-[2-(2-methylpiperidin-1-yl)ethyl]indoline-7-sulfonamide cid_3240048 1-acetyl-5-bromo-N-[2-(2-methyl-1-piperidinyl)ethyl]-2,3-dihydroindole-7-sulfonamide 5-bromanyl-1-ethanoyl-N-[2-(2-methylpiperidin-1-yl)ethyl]-2,3-dihydroindole-7-sulfonamide MLS000086264 SMR000021773 BDBM42342
US10300060, Example 7 US9763943, 7 US9993479, 7 US10765676, Example 7 US9463192, 7 BDBM249315
US9890160, Example 7 US9493457, 7 US10399973, Example 7 US8569338, 7 US9035066, 7 BDBM103940
cid_16745661 4-O-[3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxoisochromen-7-yl] 1-O-methyl butanedioate butanedioic acid O4-[3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxo-2-benzopyran-7-yl] ester O1-methyl ester CMLD003304 O4-[3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] O1-methyl butanedioate succinic acid O4-[6,8-diketo-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-isochromen-7-yl] ester O1-methyl ester BDBM52887 MLS000438854 SMR000452618
1-{3-fluoro-4-[7-(5-methyl-1H-imidazol-2- yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]- phenyl}-3-(2,4,6-trifluoro-phenyl)-urea US9758508, Compound 7 US10604508, Compound 7 BDBM340031 US11230539, Compound 7
BDBM6201 N-(1-Benzofuran-7-yl)-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine N-(1-benzofuran-7-yl)-6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine Benzofuran deriv. 10
(R)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol CHEMBL41716 BDBM50013020 7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol
5-(8-Hydroxy-7-piperidin-1-ylmethyl-isoquinolin-5-ylmethyl)-7-piperidin-1-ylmethyl-quinolin-8-ol BDBM50071612 PD-29361 CHEMBL312381
5-amino-1-(1-cyanopyrrolidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazole-4-carboxamide BDBM377713 US10815213, Example 7 US10266513, Example 7
7'-(4-(Benzyloxy)phenyl)-2'- oxo-1',4'-dihydro-2'H- spiro[pyrrolidine-3,3'- quinoline]-1-carbonitrile BDBM443234 US10654853, Example 7
7-amidinonaphthalene 40 BDBM12831 2,2,2-trifluoroacetic acid; ethyl (1R,2S)-2-[2-(7-carbamimidoylnaphthalen-1-yl)-3-phenylpropanamido]cyclohexane-1-carboxylate
BDBM421828 3-((1-(1-benzylindoline-5-carbonyl)-4-hydroxypiperidin-4-yl)methyl)-7-methylquinazolin-4(3H)-one US10508098, Example I-7
BDBM50081010 CHEMBL315372 7-Methoxy-naphthalene-2-sulfonic acid [(S)-1-(1-chloro-isoquinolin-7-ylmethyl)-2-oxo-pyrrolidin-3-yl]-amide
BDBM592662 US11572374, Example 1-85 N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-1-phenyl-3- pyrrolidinecarboxamide
BDBM749832 7-amino-7-[2-(4-fluorophenyl)- 2H-1,2,3-triazol-4-yl]-1- isoxazol-3-ylheptan-1-one US12331044, Example 123
BDBM749833 7-amino-7-[2-(4-fluorophenyl)- 2H-1,2,3-triazol-4-yl]-1- isoxazol-3-ylheptan-1-one US12331044, Example 124
CHEMBL315218 7-Methoxy-naphthalene-2-sulfonic acid [(S)-1-(1-amino-isoquinolin-7-ylmethyl)-2-oxo-pyrrolidin-3-yl]-amide BDBM50081001
CHEMBL358727 BDBM50000263 2-(3,4-Dichloro-phenyl)-1-(8-pyrrolidin-1-ylmethyl-1,4-dioxa-7-aza-spiro[4.5]dec-7-yl)-ethanone
CHEMBL85096 BDBM50081012 7-Methoxy-naphthalene-2-sulfonic acid [(S)-1-(1-hydroxy-isoquinolin-7-ylmethyl)-2-oxo-pyrrolidin-3-yl]-amide
US10336775, Example 7 BDBM408103 2-(4-(1-(Benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)thiazole US11046712, No 7
US10377742, Compound 7 US9663496, Compound 7 BDBM327868 N-(1- (cyclohexanecarbonyl) piperidin-4-yl)-5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)picolinamide
US10513507, Example I-7 BDBM425974 3-((1-(1-benzylindoline-5-carbonyl)-4-hydroxypiperidin-4-yl)methyl)-7-methylquinazolin-4(3H)-one
US10836741, Example I-7 3-((1-(1-benzylindoline-5-carbonyl)-4-hydroxypiperidin-4-yl)methyl)-7-methylquinazolin-4(3H)-one BDBM472841
US11117898, Example 7 BDBM518794 6-(2-Methoxyethoxy)-1-(4-(pyrrolidin-1-ylmethyl)benzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 7
US11542259, Compound 7 BDBM588213 1-N-[4-(6-carbamoyl-7- methoxyquinolin-4- yl)oxyphenyl]-1-N'-(4- fluorophenyl)cyclopropane-1,1- dicarboxamide
US12331044, Example 118 BDBM749827 (S)-7-amino-7-(5-(4-fluorophenyl)isoxazol-3-yl)-1-(isoxazol-3-yl)heptan-1-one
US12331044, Example 119 (R)-7-amino-7-(5-(4-fluorophenyl)isoxazol-3-yl)-1-(isoxazol-3-yl)heptan-1-one BDBM749828
US20240358679, Compound 7 1-methyl-3-phenyl-5-(4-pyrrolidine-1-yl)benzylidene-2-selenoxoimidazolidine-4-on BDBM617731 US20230286956, Compound 7
(S)-UH-301 BDBM50013019 CHEMBL22778 (S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydronaphthalen-1-ol (S)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol 7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol 7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol ((S)-UH301) UH-301
1-[2-(dimethylamino)ethylamino]-4-methyl-7-oxidanyl-thioxanthen-9-one BDBM114645 cid_432873 SMR001565401 1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-methyl-9-thioxanthenone 1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-methyl-thioxanthen-9-one MLS002701807 1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-methylthioxanthen-9-one
BDBM80874 1-[2-(4-tert-butylphenoxy)ethyl]-7-methyl-isatin cid_2200159 1-[2-(4-tert-butylphenoxy)ethyl]-7-methylindole-2,3-dione SMR000199323 1-[2-(4-tert-butylphenoxy)ethyl]-7-methyl-indole-2,3-dione MLS000580079 1-[2-(4-tert-butylphenoxy)ethyl]-7-methyl-1H-indole-2,3-dione
ethyl 1-(4-nitro-2,1,3-benzoxadiazol-7-yl)piperidine-3-carboxylate MLS000729233 SMR000307511 1-(4-nitro-2,1,3-benzoxadiazol-7-yl)-3-piperidinecarboxylic acid ethyl ester 1-(7-nitrobenzofurazan-4-yl)nipecotic acid ethyl ester cid_4871598 ethyl 1-(7-nitro-2,1,3-benzoxadiazol-4-yl)piperidine-3-carboxylate BDBM51123
US10040790, Example 7 7-amino-3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-methyl-8-phenoxy-3,4-dihydropyrido[4,3-d]pyrimidin-2(1H)-one US11530214, Example 7 US10450313, Example 7 BDBM278491 US10947230, Example 7
(S)-1-(4-(1-(7-amino-2-(5- BDBM683659 US20240217978, Example 315
1-(1'-((7-amino-2-(furan-2-yl)- US20240217978, Example 290 BDBM683634
1-(3-(hydroxymethyl)phenyl)-3-(7-hydroxynaphthalen-1-yl)urea BDBM50344357 CHEMBL1779677
1-(4-(methylthio)oxazol-2-yl)-7-phenylheptan-1-one CHEMBL461363 BDBM50247070
1-(7-hydroxynaphthalen-1-yl)-3-(2-(trifluoromethyl)phenyl)urea CHEMBL1779664 BDBM50344344
1-(7-hydroxynaphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea CHEMBL1779665 BDBM50344345
1-(7-hydroxynaphthalen-1-yl)-3-(4-(trifluoromethyl)phenyl)urea BDBM50344346 CHEMBL1779666
1-(phenylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydroquinoline CHEMBL209139 BDBM50186286
1-Phenylbenzimidazole deriv. 84 7-methyl-1-phenyl-1H-1,3-benzodiazole BDBM3867
1-Phenylbenzimidazole deriv. 85 7-methoxy-1-phenyl-1H-1,3-benzodiazole BDBM3868
1-Phenylbenzimidazole deriv. 91 BDBM3874 7-nitro-1-phenyl-1H-1,3-benzodiazole
1-Phenylbenzimidazole deriv. 92 BDBM3875 1-phenyl-1H-1,3-benzodiazol-7-amine
1-[4,5'']Bioxazolyl-2''-yl-7-phenyl-heptan-1-one BDBM50157137 CHEMBL181957
1-phenyl-1H-1,3-benzodiazol-7-ol 1-Phenylbenzimidazole deriv. 86 BDBM3869
3-(7-Indol-1-yl-heptyloxycarbonyl)-1-methyl-pyridinium; iodide CHEMBL441469 BDBM50130815
BDBM3870 7-chloro-1-phenyl-1H-1,3-benzodiazole 1-Phenylbenzimidazole deriv. 87
BDBM3873 1-phenyl-1H-1,3-benzodiazole-7-carboxamide 1-Phenylbenzimidazole deriv. 90
BDBM50186318 CHEMBL210346 1-(cyclohexylmethyl)-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydroquinoline
BDBM50327829 CHEMBL1256163 US9296693, 7 1-Phenyl-3-(1-propionylpiperidin-4-yl)urea
CHEMBL210761 BDBM50186299 1-ethyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydroquinoline
CHEMBL460316 7-phenyl-1-(4-phenyloxazol-2-yl)heptan-1-one BDBM50247104
CHEMBL477371 7-Phenyl-1-(1,3,4-thiadiazol-2-yl)-heptan-1-one BDBM50262419
N-Benzoylimidazole 1-benzoyl-1H-imidazole Imidazole N-1 deriv. 7 BDBM7946
US10239843, Example 484 BDBM371376 1-Chloro-N-(1-methylcyclopropyl)isoquinoline-7-sulfonamide
US10562878, Compound 7 1-(1-(biphenyl-4-yl)cyclohexyl)ethanamine CHEMBL1684054 BDBM50337908
BDBM200579 US10590139, Example 7 US9227975, 7 US9795611, 7 US10011604, 7
US8476284, 7 BDBM97677 US9133201, 7 US8497277, 7 US20240358707, Compound 7
US8940744, 7 US11040980, Example 7 US9266895, 7 BDBM143182 US9994576, 7
1'-({7-Chloro-1-[2- (methylsulfonyl)ethyl]-1H-indol-2- yl}methyl)spiro[cyclopropane-1,3'- pyrrolo[2,3-c]pyridin]-2'(1'H)-one US10189838, Example 1-7 BDBM324643
7-Phenyl-1-(5-pyridazin-3-yl-oxazol-2-yl)-heptan-1-one BDBM50163213 7-phenyl-1-(5-(pyridazin-3-yl)oxazol-2-yl)heptan-1-one CHEMBL367307
7-phenyl-1-(5-(pyrimidin-4-yl)oxazol-2-yl)heptan-1-one BDBM50163177 CHEMBL177922 7-Phenyl-1-(5-pyrimidin-4-yl-oxazol-2-yl)-heptan-1-one
7-phenyl-1-(5-(pyrimidin-5-yl)oxazol-2-yl)heptan-1-one CHEMBL175761 7-Phenyl-1-(5-pyrimidin-5-yl-oxazol-2-yl)-heptan-1-one BDBM50163195
BDBM50163166 7-Phenyl-1-(5-thiophen-2-yl-oxazol-2-yl)-heptan-1-one CHEMBL178071 7-phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-one
CHEMBL368284 7-Phenyl-1-(5-pyrimidin-2-yl-oxazol-2-yl)-heptan-1-one BDBM50163207 7-phenyl-1-(5-(pyrimidin-2-yl)oxazol-2-yl)heptan-1-one
(4-chlorophenyl)-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]methanone SMR000296226 cid_1251584 BDBM43528 MLS000676065 7-chloro-4-[4-(4-chlorobenzoyl)-1-piperazinyl]quinoline (4-chlorophenyl)-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]methanone (4-chlorophenyl)-[4-(7-chloro-4-quinolyl)piperazino]methanone [4-(7-chloranylquinolin-4-yl)piperazin-1-yl]-(4-chlorophenyl)methanone
BDBM6649 N-(7-Hydroxy-1-naphthyl)-N -(1,3-thiazol-2-yl)urea Diarylurea deriv. 1d 1-(7-hydroxynaphthalen-1-yl)-3-1,3-thiazol-2-ylurea
N-(1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(5-phenyl-2-pyridine-1-yl)-3-pyridinecarboxamide US9987259, Example 7 BDBM397115 US10456385, Example 7
US9828381, 7-1 BDBM360713 2-{1-[5-methyl-2-(tricyclo[3.3.1.13′]dec-1-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidin-2-yl}ethanol
CHEMBL178398 BDBM50161512 7-phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)heptan-1-one 7-Phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)-heptan-1-one 7-Phenyl-1-(5-pyridin-2-yl-[1,3,4]oxadiazol-2-yl)-heptan-1-one
1-ethyl-6-fluoro-7-(4-nonanoylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid cid_3672184 1-ethyl-6-fluoranyl-7-(4-nonanoylpiperazin-1-yl)-4-oxidanylidene-quinoline-3-carboxylic acid 1-ethyl-6-fluoro-4-keto-7-(4-pelargonylpiperazino)quinoline-3-carboxylic acid SMR000539457 1-ethyl-6-fluoro-4-oxo-7-[4-(1-oxononyl)-1-piperazinyl]-3-quinolinecarboxylic acid BDBM78975 MLS001164078
MLS000038128 4-hydroxy-3-keto-7-methoxy-1-oxido-quinoxalin-1-ium-2-carboxylic acid methyl ester cid_659722 SMR000040768 4-hydroxy-7-methoxy-1-oxido-3-oxo-2-quinoxalin-1-iumcarboxylic acid methyl ester methyl 7-methoxy-1-oxidanidyl-4-oxidanyl-3-oxidanylidene-quinoxalin-1-ium-2-carboxylate BDBM50782 methyl 4-hydroxy-7-methoxy-1-oxido-3-oxoquinoxalin-1-ium-2-carboxylate
SMR000095108 1-(3-amino-7-methoxy-pyrazolo[3,4-b]quinolin-1-yl)-2-(2-methoxyphenyl)ethanone 1-(3-azanyl-7-methoxy-pyrazolo[3,4-b]quinolin-1-yl)-2-(2-methoxyphenyl)ethanone BDBM48966 1-(3-amino-7-methoxypyrazolo[3,4-b]quinolin-1-yl)-2-(2-methoxyphenyl)ethanone MLS000118160 1-(3-amino-7-methoxy-1-pyrazolo[3,4-b]quinolinyl)-2-(2-methoxyphenyl)ethanone cid_5307507
SMR000127611 1-(3-amino-7-methoxypyrazolo[3,4-b]quinolin-1-yl)-2-(4-chlorophenyl)ethanone 1-(3-azanyl-7-methoxy-pyrazolo[3,4-b]quinolin-1-yl)-2-(4-chlorophenyl)ethanone cid_6619057 1-(3-amino-7-methoxy-1-pyrazolo[3,4-b]quinolinyl)-2-(4-chlorophenyl)ethanone 1-(3-amino-7-methoxy-pyrazolo[3,4-b]quinolin-1-yl)-2-(4-chlorophenyl)ethanone BDBM40184 MLS000522343
MLS000086510 SMR000022405 ethyl 1-[[5-bromo-1-(cyclopropanecarbonyl)-2,3-dihydroindol-7-yl]sulfonyl]piperidine-3-carboxylate cid_3244145 1-[5-bromo-1-(cyclopropanecarbonyl)indolin-7-yl]sulfonylnipecotic acid ethyl ester ethyl 1-{[5-bromo-1-(cyclopropylcarbonyl)-2,3-dihydro-1H-indol-7-yl]sulfonyl}piperidine-3-carboxylate 1-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-3-piperidinecarboxylic acid ethyl ester ethyl 1-[(5-bromanyl-1-cyclopropylcarbonyl-2,3-dihydroindol-7-yl)sulfonyl]piperidine-3-carboxylate BDBM42937
ethyl 4-[(5-bromanyl-1-cyclopropylcarbonyl-2,3-dihydroindol-7-yl)sulfonyl]piperazine-1-carboxylate 4-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-1-piperazinecarboxylic acid ethyl ester ethyl 4-{[5-bromo-1-(cyclopropylcarbonyl)-2,3-dihydro-1H-indol-7-yl]sulfonyl}piperazine-1-carboxylate cid_3238590 MLS000086504 ethyl 4-[[5-bromo-1-(cyclopropanecarbonyl)-2,3-dihydroindol-7-yl]sulfonyl]piperazine-1-carboxylate SMR000022399 BDBM68489 4-[5-bromo-1-(cyclopropanecarbonyl)indolin-7-yl]sulfonylpiperazine-1-carboxylic acid ethyl ester
5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-(1H-pyrazol-4-ylmethyl)pyrazolo[4,3-b]pyridin-7-amine US10512632, Example 7 US11026923, Example 7 US11491140, Example 7 US10766893, Example S7 US11634416, Example 7 BDBM278977 US10034861, Example 7 US10806718, Example 7
BDBM38386 MLS000091801 2-(azepan-1-ylcarbonyl)-7-methylfuro[2,3-b]quinoline azepan-1-yl-(7-methylfuro[2,3-b]quinolin-2-yl)methanone SMR000026348 cid_3236052 1-azepanyl-(7-methyl-2-furo[2,3-b]quinolinyl)methanone
BDBM83206 cid_3372218 MLS-0103364.0001 1-[3-(4-tert-butylphenoxy)propyl]-7-methyl-indole-2,3-dione 1-[3-(4-tert-butylphenoxy)propyl]-7-methyl-isatin 1-[3-(4-tert-butylphenoxy)propyl]-7-methylindole-2,3-dione
7-(Azetidin-1-yl)-8-(7-methyl-1H-indazol-5-yl)-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridine BDBM311769 US10155769, Example 7
BDBM592896 US11572374, Example 23-7 N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-(2,3- dichlorophenyl)-1-pyrrolidinecarboxamide
N-(1-(methylsulfonyl)piperidin-4-yl)-8-(2-oxa-7-azaspiro[4.5]decan-7-yl)quinazolin-2-amine US20240092761, Compound 7 BDBM659309
US10533001, Example 7 2-(4-(4- acetylpiperazin-1- yl)phenylamino)-4- (isopropylamino) pyrimidine-5- carboxamide BDBM365323 US9868729, Example 7 US11414410, Example 7
US9771366, Compound 7 US10758530, Compound 7 US10081632, Compound 7 1-benzyl-N-(3-(morpholinomethyl)benzofuran-6-yl)-1H-pyrazole-4-carboxamide BDBM286080
(R)-1-(3-(3-(4-(naphthalen-1- yloxy)phenyl)-1H-pyrazolo[4,3-c]pyridin- 1-yl)pyrrolidin-1-yl)prop-2-en-1-one BDBM444637 US10662187, Compound 7 US10793566, Compound 7
BDBM66740 MLS001213303 7-butyl-3-methyl-8-pyrrolidino-xanthine cid_3457383 SMR000540609 7-butyl-3-methyl-8-(1-pyrrolidinyl)purine-2,6-dione 7-butyl-3-methyl-8-pyrrolidin-1-ylpurine-2,6-dione 7-butyl-3-methyl-8-pyrrolidin-1-yl-purine-2,6-dione
(7-Aminomethyl-bicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)-acetic acid; hydrochloride CHEMBL545618 BDBM50009136
1-acetyl-2,3-dihydro-1H-indole-2,3-dione Acetylisatin (Compound 7) BDBM22787 Isatin-based compound, 7
2-(1-Hydroxy-cyclopentyl)-7-phenyl-7-pyridin-3-yl-hept-6-enoic acid BDBM50026533 CHEMBL318048
BDBM110116 US8609678, 2-(4-benzylpiperazin-1-yl)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide [169]
BDBM110120 US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(4-phenylpiperazin-1-yl)pyrimidine-5-carboxamide [173]
BDBM110126 US8609678, 2-(4-carbamoylpiperidin-1-yl)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide [179]
BDBM110135 US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(4-methylpiperazin-1-yl)pyrimidine-5-carboxamide [188]
BDBM50026547 2-Cyclopent-1-enyl-7-phenyl-7-pyridin-3-yl-hept-6-enoic acid CHEMBL98845
CHEMBL237044 BDBM26748 bisarylimidazole derivative, 7 ethyl 7-(2-ethyl-4,5-diphenyl-1H-imidazol-1-yl)heptanoate
US8609678, 2-(1,4-diazepan-1-yl)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide [186] BDBM110133
US10961241, Example 7 (6S,8R)-7-((1-fluorocyclopropyl)methyl)-6-(4-((1-(3-fluoropropyl)azetidin-3-yl)oxy)-2-methoxyphenyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinoline US10590130, Example 7 US10131663, Example 7 BDBM300931
1'-butyl-7'-methyl-2'-spiro[1,3-dioxane-2,3'-indole]one MLS001163078 1'-butyl-7'-methylspiro[1,3-dioxane-2,3'-indole]-2'-one 1'-butyl-7'-methyl-spiro[1,3-dioxane-2,3'-indoline]-2'-one SMR000499393 cid_18889437 1'-butyl-7'-methylspiro[1,3-dioxane-2,3'-indol]-2'(1'H)-one 1'-butyl-7'-methyl-spiro[1,3-dioxane-2,3'-indole]-2'-one BDBM73851
SMR000452711 2-quinoxalinecarboxylic acid [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxo-2-(phenylmethyl)-7-isoquinolinyl] ester MLS000438662 quinoxaline-2-carboxylic acid [2-benzyl-6,8-diketo-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-7-isoquinolyl] ester [2-benzyl-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxoisoquinolin-7-yl] quinoxaline-2-carboxylate cid_16745599 [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-bis(oxidanylidene)-2-(phenylmethyl)isoquinolin-7-yl] quinoxaline-2-carboxylate BDBM93698
cid_16759696 quinoxaline-2-carboxylic acid [2-cyclopropyl-6,8-diketo-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-7-isoquinolyl] ester 2-quinoxalinecarboxylic acid [2-cyclopropyl-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxo-7-isoquinolinyl] ester BDBM93608 [2-cyclopropyl-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-bis(oxidanylidene)isoquinolin-7-yl] quinoxaline-2-carboxylate MLS000438657 SMR000452706 [2-cyclopropyl-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxoisoquinolin-7-yl] quinoxaline-2-carboxylate
quinoxaline-2-carboxylic acid [6,8-diketo-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-2-phenyl-7-isoquinolyl] ester MLS000438675 cid_16745602 [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxo-2-phenylisoquinolin-7-yl] quinoxaline-2-carboxylate 2-quinoxalinecarboxylic acid [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxo-2-phenyl-7-isoquinolinyl] ester CMLD004012 [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-bis(oxidanylidene)-2-phenyl-isoquinolin-7-yl] quinoxaline-2-carboxylate BDBM76128 SMR000452724
BDBM174776 US9540388, 7 US10053462, 7 US9102686, 7
US9388176, 7 US9820989, 7 US8889870, 7 BDBM139547
US9655879, 7 BDBM158079 US9024044, 7 US9227949, 7
7-allyl-8-(azepan-1-yl)-1,3-dimethyl-xanthine SMR000011042 8-(azepan-1-yl)-1,3-dimethyl-7-prop-2-enylpurine-2,6-dione 8-(1-azepanyl)-1,3-dimethyl-7-prop-2-enylpurine-2,6-dione MLS000030597 BDBM50002 7-Allyl-8-azepan-1-yl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione cid_653061 8-(azepan-1-yl)-1,3-dimethyl-7-prop-2-enyl-purine-2,6-dione
7-ethyl-1-(2-morpholin-4-yl-2-oxoethyl)indole-3-carbonitrile cid_900744 7-ethyl-1-(2-keto-2-morpholino-ethyl)indole-3-carbonitrile SMR000075324 7-ethyl-1-[2-(4-morpholinyl)-2-oxoethyl]-1H-indole-3-carbonitrile 7-ethyl-1-[2-(4-morpholinyl)-2-oxoethyl]-3-indolecarbonitrile BDBM30903 MLS000049392 7-ethyl-1-(2-morpholin-4-yl-2-oxidanylidene-ethyl)indole-3-carbonitrile
MLS000086257 SMR000021766 1-acetyl-5-bromo-N-(2-pyridinylmethyl)-2,3-dihydroindole-7-sulfonamide 1-acetyl-5-bromo-N-(pyridin-2-ylmethyl)indoline-7-sulfonamide 5-bromanyl-1-ethanoyl-N-(pyridin-2-ylmethyl)-2,3-dihydroindole-7-sulfonamide BDBM41779 1-acetyl-5-bromo-N-(2-pyridylmethyl)indoline-7-sulfonamide 1-acetyl-5-bromo-N-(pyridin-2-ylmethyl)-2,3-dihydroindole-7-sulfonamide cid_3242806
SMR001566699 1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-(hydroxymethyl)-9-thioxanthenone 1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-methylol-thioxanthen-9-one 9H-Thioxanthen-9-one, 1-[[2-(dimethylamino)ethyl]amino]-7-hydroxy-4-(hydroxymethyl)- MLS002702881 BDBM114643 1-[2-(dimethylamino)ethylamino]-4-(hydroxymethyl)-7-oxidanyl-thioxanthen-9-one cid_333459 1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-(hydroxymethyl)thioxanthen-9-one
cid_1908550 SMR000211941 7-(2,4-dinitrophenoxy)-1-benzopyran-2-one BDBM72228 7-(2,4-Dinitro-phenoxy)-chromen-2-one 7-(2,4-dinitrophenoxy)chromen-2-one 7-(2,4-dinitrophenoxy)coumarin MLS000588020
BDBM50906 ethyl 4-hydroxy-7-methoxy-1-oxido-3-oxoquinoxalin-1-ium-2-carboxylate 4-hydroxy-7-methoxy-1-oxido-3-oxo-2-quinoxalin-1-iumcarboxylic acid ethyl ester SMR000145219 3-Hydroxy-7-methoxy-1,4-dioxy-quinoxaline-2-carboxylic acid ethyl ester ethyl 7-methoxy-1-oxidanidyl-4-oxidanyl-3-oxidanylidene-quinoxalin-1-ium-2-carboxylate 4-hydroxy-3-keto-7-methoxy-1-oxido-quinoxalin-1-ium-2-carboxylic acid ethyl ester MLS000551293 cid_1899681
1',7',7'-trimethyl-2,3-dihydrospiro(4H-1,3-benzoxazine-2,2'-bicyclo[2.2.1]heptane)-4-one BDBM80922 cid_11834625 4',7',7'-trimethyl-4-spiro[3H-1,3-benzoxazine-2,3'-bicyclo[2.2.1]heptane]one SMR000224535 MLS000701521 1',7',7'-trimethylspiro[3H-1,3-benzoxazine-2,2'-norbornane]-4-one 4',7',7'-trimethylspiro[3H-1,3-benzoxazine-2,3'-bicyclo[2.2.1]heptane]-4-one
BDBM239010 US9597317, 7 US10478423, Cpd. 7 US10028934, Compound 7 US9408850, 7
US9694016, 7 BDBM202662 US10709712, Example 7 US10245267, Example 7 US9242969, 7
(S)-7-(1-(4-(pyrimidin-2-yl)piperazin-1-yl)ethyl)quinolone or (R)-7-(1-(4-(pyrimidin-2-yl)piperazin-1-yl)ethyl)quinoline US10336775, Example 95 BDBM408191
1-(3-((7-methoxy-4-((1- methyl-1H-indazol-7-yl)- amino)quinazolin-6-yl)- oxy)pyrrolidin-1-yl)prop-2- en-1-one BDBM557902 US11365189, Ex. No. 56
1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-butan-1-one BDBM50063781 1-(7-tert-butyl-3,3-dimethyl-2,3-dihydrobenzofuran-5-yl)butan-1-one CHEMBL13980
BDBM484204 US11554118, Compound 7 US10933063, Compound 7 (S)-1-(2-(1-(4-(3- fluorophenoxy)phenyl)imidazo[1,5- a]pyrazin-3-yl)pyrrolidin-1-yl)but-2- yn-1-one
BDBM557889 1-(4-((7-methoxy-4-((1- methyl-1H-indazol-7-yl)- amino)quinazolin-6-yl)- oxy)piperidin-1-yl)prop-2- en-1-one US11365189, Ex. No. 26
US11365189, Ex. No. 53 1-(3-((7-methoxy-4-((1- methyl-1H-indazol-7-yl)- amino)quinazolin-6-yl)- oxy)azetidin-1-yl)prop-2- en-1-one BDBM557879
((R)-1-Phenyl-ethyl)-[7- US10730882, Example 12 BDBM455377
1-(4-Fluoro-benzofuran-7-yl)-piperazine CHEMBL305308 BDBM50035063
1-(4-bromobenzyl)-7-fluoroindoline-2,3-dione CHEMBL468925 BDBM50258528
1-(5-Fluoro-benzofuran-7-yl)-piperazine BDBM50035041 CHEMBL432134
1-(5-Methoxy-benzofuran-7-yl)-piperazine CHEMBL57583 BDBM50035064
1-Benzofuran-7-yl-4-butyl-piperazine CHEMBL280825 BDBM50039809
1-Benzofuran-7-yl-4-cyclohexyl-piperazine CHEMBL28110 BDBM50039823
1-Benzofuran-7-yl-4-cyclohexylmethyl-piperazine BDBM50039816 CHEMBL27655
1-Benzofuran-7-yl-4-cyclopropylmethyl-piperazine CHEMBL416382 BDBM50039808
1-Benzofuran-7-yl-4-decyl-piperazine BDBM50039804 CHEMBL26355
1-Benzofuran-7-yl-4-hexyl-piperazine BDBM50039805 CHEMBL27558
2-Benzyl-7-methoxy-naphthalen-1-ol BDBM50012711 CHEMBL122780
7-(4,4,4-Trifluorobutoxy)-1-methyl-beta-carboline BDBM50333418 CHEMBL1645547
7-(Benzyloxy)-3,4-dihydronaphthalen-1(2H)-one (4a) BDBM166630
7-Amino-5,6,7,8-tetrahydro-naphthalen-1-ol BDBM50020495 CHEMBL144715
7-Dibutylamino-5,6,7,8-tetrahydro-naphthalen-1-ol BDBM50016773 CHEMBL351641
7-Dibutylamino-5,6,7,8-tetrahydro-naphthalen-1-ol BDBM50016775 CHEMBL423987
7-Diethylamino-5,6,7,8-tetrahydro-naphthalen-1-ol BDBM50016776 CHEMBL349409
7-Fluoro-1-methyl-9H-beta-carboline BDBM50111435 CHEMBL14445
7-Piperazin-1-yl-benzofuran-6-carbonitrile BDBM50035045 CHEMBL303771
BDBM50028714 7-Imidazol-1-yl-heptanoic acid; hydrochloride CHEMBL557994
BDBM50030007 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-carbonitrile CHEMBL27720
BDBM50030013 CHEMBL134574 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-carbonitrile
BDBM50030023 CHEMBL134551 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-carbonitrile
BDBM50035046 1-(4-Methoxy-benzofuran-7-yl)-piperazine CHEMBL61438
BDBM50035047 CHEMBL61242 1-(6-Fluoro-benzofuran-7-yl)-piperazine
BDBM50035048 1-(2-Methyl-benzofuran-7-yl)-piperazine CHEMBL61028
BDBM50035049 CHEMBL62195 1-(6-Nitro-benzofuran-7-yl)-piperazine
BDBM50035059 1-Benzo[b]thiophen-7-yl-piperazine CHEMBL60809
BDBM50035061 1-(4-Bromo-benzofuran-7-yl)-piperazine CHEMBL58591
BDBM50039795 1-Benzofuran-7-yl-4-pentyl-piperazine CHEMBL26834
BDBM50039815 1-Benzofuran-7-yl-4-ethyl-piperazine CHEMBL329246
BDBM50039820 1-Benzofuran-7-yl-4-propyl-piperazine CHEMBL26645
BDBM50039825 CHEMBL96658 1-Benzofuran-7-yl-4-isobutyl-piperazine
BDBM50039832 1-Benzofuran-7-yl-4-octyl-piperazine CHEMBL26988
BDBM50126272 CHEMBL283016 1-Isoquinolin-7-yl-3-phenyl-urea
BDBM50147402 CHEMBL323241 N-(7-Phenyl-isoquinolin-1-yl)-guanidine
BDBM50147405 N-(7-Hydroxymethyl-isoquinolin-1-yl)-guanidine CHEMBL324663
BDBM50147406 CHEMBL321848 N-(7-Bromo-isoquinolin-1-yl)-guanidine
BDBM50147407 N-(7-Methoxy-isoquinolin-1-yl)-guanidine CHEMBL110307
BDBM50261509 [Gly8, aib22]GLP-1(7-37)-NH2 CHEMBL499370
BDBM683630 US20240217978, Example 286 (S)-(1-(7-amino-2-
CHEMBL129661 BDBM50061300 1-(7-Methoxy-naphthalen-2-yl)-piperazine
CHEMBL164814 7-Diethylamino-5,6,7,8-tetrahydro-naphthalen-1-ol BDBM50016771
CHEMBL168114 BDBM50016772 7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
CHEMBL1766976 2-(1-Naphthylsulfonyl)-1,2,3,4-tetrahydro-7-isoquinolinol BDBM50341436
CHEMBL26819 1-Benzofuran-7-yl-4-isopropyl-piperazine BDBM50039828
CHEMBL286287 1-Benzofuran-7-yl-4-methyl-piperazine BDBM50039830
CHEMBL291572 1-(5-Methyl-benzofuran-7-yl)-piperazine BDBM50035060
CHEMBL301049 1-(5-Bromo-benzofuran-7-yl)-piperazine BDBM50035043
CHEMBL301451 BDBM50035044 1-(3-Methyl-benzofuran-7-yl)-piperazine
CHEMBL36580 BDBM50014658 7-Methoxy-1-methyl-isoquinolin-6-ol
CHEMBL423807 7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-1-ol BDBM50016770
CHEMBL59340 1-(3-Bromo-benzofuran-7-yl)-piperazine BDBM50035053
CHEMBL59396 BDBM50035052 1-(4-Methyl-benzofuran-7-yl)-piperazine
N-(7-Benzyloxy-isoquinolin-1-yl)-guanidine BDBM50147425 CHEMBL107872
US8598345, 203 BDBM107261 US8598345, Table 1-48/2-7
[3-(1-methylbenzimidazol-2-yl)-2-oxidanylidene-chromen-7-yl] ethanoate [3-(1-methylbenzimidazol-2-yl)-2-oxochromen-7-yl] acetate BDBM30985 MLS000107096 cid_708260 acetic acid [2-keto-3-(1-methylbenzimidazol-2-yl)chromen-7-yl] ester SMR000111468 acetic acid [3-(1-methyl-2-benzimidazolyl)-2-oxo-1-benzopyran-7-yl] ester
cid_2442378 SMR000369205 BDBM46975 2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]-5-piperidin-1-ylsulfonylpyridine MLS001002674 2-(2,2-dimethylcoumaran-7-yl)oxy-5-piperidinosulfonyl-pyridine 2-[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]-5-piperidin-1-ylsulfonyl-pyridine 2-[(2,2-dimethyl-3H-benzofuran-7-yl)oxy]-5-(1-piperidinylsulfonyl)pyridine
1-(3,4-Dichloro-benzyl)-3-(7-hydroxy-naphthalen-1-yl)-1-methyl-urea BDBM50138510 CHEMBL405658
1-(7-Hydroxy-naphthalen-1-yl)-3-[1-(4-trifluoromethyl-phenyl)-ethyl]-urea CHEMBL357738 BDBM50138516
1-[16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10,12,14-hexaen-1-yl]-1-propanone BDBM50013497 CHEMBL275346
3-phenyl-1-(2-(7-(piperidin-1-yl)heptyloxy)phenyl)propan-1-one CHEMBL223078 BDBM50207943
BDBM50204524 7-phenyl-1-(5-(piperidine-1-carbonyl)oxazol-2-yl)heptan-1-one CHEMBL376417
CHEMBL1779832 3-(4-chloro-3-(trifluoromethyl)phenyl)-1-(7-hydroxynaphthalen-1-yl)-1-methylurea BDBM50344368
CHEMBL379401 BDBM50182930 3-(3-cyano-1-methyl-1H-indol-7-yl)-1-methyl-1-phenylurea
1-(3-chlorophenyl)-N-((1R,2R,4S)-7-cyano- 7-azabicyclo[2.2.1]heptan-2-yl)-3- piperidinecarboxamide US11572374, Example 1-92 BDBM592669
3-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXY-1-NAPHTHONITRILE BDBM50168348 3-(3-Fluoro-4-hydroxy-phenyl)-7-hydroxy-naphthalene-1-carbonitrile CHEMBL192154
3-[(3R)-1-(3- methoxypropanoyl)piperidin- 3-yl]-1-(4- phenoxyphenyl)-1H- pyrazolo[3,4-c]pyridin-7- amine BDBM326004 US9637486, Example 7
7-amino-7-(5-(2-methylquinolin-6-yl)oxazol-2-yl)-1-(oxazol-2-yl)heptan-1-one BDBM749735 US12331044, Example 26
7-methyl-1-[3-(2-methylphenoxy)propyl]indole-2,3-dione cid_2141781 SMR000092492 7-methyl-1-[3-(2-methylphenoxy)propyl]isatin MLS000115365 BDBM114465
BDBM121308 US8722896, (-)-(3R)-1-(N-methyl-indolin-7- ylmethyl)-N-(9-chloro-2,3,4,5- tetrahydro-1-benzoxepin-7- ylmethyl)-N-isobutylpyrrolidine- 3-carboxamide
BDBM13958 Oxalylarylaminobenzoic Acid Analog 8b 2-[(7-Hydroxynaphthalen-1-yl)oxalylamino]benzoic Acid 2-[(7-hydroxynaphthalen-1-yl)amidoformic acid]benzoic acid
BDBM55885 1-methyl-2,9-dihydro-beta-carbolin-7-one Harmol cid_68094 SMR000528328 MLS000736795 1-methyl-2,9-dihydropyrido[3,4-b]indol-7-one
BDBM592665 US11572374, Example 1-88 1-(3-chlorophenyl)-N-((1R,2R,4S)-7-cyano- 7-azabicyclo[2.2.1]heptan-2-yl)-3- pyrrolidinecarboxamide
BDBM749745 US12331044, Example 36 (S)-7-amino-7-(5-(2-fluorophenyl)-1H-imidazol-2-yl)-1-(oxazol-4-yl)heptan-1-one
BDBM749746 (S)-7-amino-7-(5-(2-fluorophenyl)-1H-imidazol-2-yl)-1-(isoxazol-3-yl)heptan-1-one US12331044, Example 37
Imidazopyridazine 30 7-[5-methyl-2-(4H-1,2,4-triazol-4-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one BDBM3390
Imidazopyridazine 32 7-[5-methyl-2-(2H-1,2,3-triazol-2-yl)imidazo[1,5-a]pyridazin-7-yl]-1-phenylheptan-1-one BDBM3391
Quinoxaline-2-carboxylic acid [(1S,2S)-1-benzyl-7-fluoro-2-hydroxy-7-methyl-4-(pyrrolidine-1-carbonyl)-octyl]-amide CHEMBL68692 BDBM50144418
US12331044, Example 107 BDBM749816 N-(1-(5-(2-fluorophenyl)oxazol-2-yl)-7-(isoxazol-3-yl)-7-oxoheptyl)-1-methylazetidine-3-carboxamide
US20250154147, Example 7 6-isopropyl-1-methyl-4-[[(1R)-1-[3- (trifluoromethyl)phenyl]ethyl]amino] pyrido[3,4-d]pyridazin-7-one BDBM740586
US8722896, (-)-(3R)-1-(N-methyl-indol-7- ylmethyl)-N-(9-chloro-2,3,4,5- tetrahydro-1-benzoxepin-7- ylmethyl)-N-isobutylpiperidine- 3-carboxamide BDBM121301
US8722896, (-)-(3R)-1-(N-methyl-indol-7- ylmethyl)-N-(9-chloro-2,3,4,5- tetrahydro-1-benzoxepin-7- ylmethyl)-N-isobutylpyrrolidine- 3-carboxamide BDBM121286
(3R)-1-(3-chlorophenyl)-N-((1R,2R,4S)-7- cyano-7-azabicyclo[2.2.1]heptan-2-yl)-5-oxo- 3-pyrrolidinecarboxamide US11572374, Example 26-1-1 BDBM592903
(S)-7-amino-7-(1-ethyl-4-(2-methylquinolin-6-yl)-1H-imidazol-2-yl)-1-(oxazol-2-yl)heptan-1-one BDBM749739 US12331044, Example 30
BDBM50333718 (S)-1-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(2-(3,5-dimethylphenyl)-3-(1-(propylamino)ethyl)-1H-indol-5-yl)-2-methylpropan-1-one CHEMBL1643712
BDBM749738 (S)-7-amino-7-(1-methyl-4-(2-methylquinolin-6-yl)-1H-imidazol-2-yl)-1-(oxazol-2-yl)heptan-1-one US12331044, Example 29
Cis-N-(1-(3-(azetidin-1-yl)-4-benzyl-7-fluorochroman-6-yl)azetidin-3-yl)-1-ethyl-1H-1,2,3-triazole-4-sulfonamide US9586945, 7 BDBM294250
US11572374, Example 1-1 BDBM592509 N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-(1H-pyrrol- 1-yl)-1,3-benzothiazole-6-carboxamide
SMR000178229 cid_1076113 2-[(7-methyl-2-piperidin-1-yl-quinolin-3-yl)methylidene]propanedinitrile BDBM44512 2-[[7-methyl-2-(1-piperidinyl)-3-quinolinyl]methylidene]propanedinitrile 2-(7-Methyl-2-piperidin-1-yl-quinolin-3-ylmethylene)-malononitrile MLS000549748 2-[(7-methyl-2-piperidino-3-quinolyl)methylene]malononitrile 2-[(7-methyl-2-piperidin-1-ylquinolin-3-yl)methylidene]propanedinitrile
[4-(7-chloroquinolin-4-yl)piperazin-1-yl]-(furan-2-yl)methanone 7-chloro-4-[4-(2-furoyl)-1-piperazinyl]quinoline BDBM75816 [4-(7-chloro-4-quinolinyl)-1-piperazinyl]-(2-furanyl)methanone cid_2823713 SMR000297211 [4-(7-chloranylquinolin-4-yl)piperazin-1-yl]-(furan-2-yl)methanone [4-(7-chloro-4-quinolyl)piperazino]-(2-furyl)methanone MLS000675961
SMR000486244 7-fluoro-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one 7-fluoranyl-6-methoxy-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one cid_616433 7-fluoro-6-methoxy-2,3,4,9-tetrahydro-beta-carbolin-1-one BDBM66737 7-fluoro-6-methoxy-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one MLS001060771
US20250092039, Compound 162 Preparation of 3-[5-[2-[4-[[1-[[7-(8-ethyl-7-fluoro-3-hydroxy-1-naphthyl)-8-fluoro-4-1(3R)-3-hydroxy-3-methyl-1-piperidyl]pyrido[4,3-d]pyrimidin-2-yl]oxymethyl]cyclopropyl]methyl]piperazin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-1-oxo-isoindolin-2-yl]piperidine-2,6-dione BDBM728333
BDBM118354 US11667644, Example 7 USRE48841, Example 7 US11059828, Example 7 US9586962, Example 7 US8653263, 7
BDBM164813 US10604504, Example 7 US9920031, Example 7 US9688629, 7 US9802915, Example 7 US11623921, Example 7
US9718822, 7 US9750744, Example 7 US10966985, Compound 7 US9902741, Example 7 US10688100, Compound 7 BDBM267414
US9796724, Example 7 US8791123, 7 US10251889, Example 7 US10758542, Example 7 US9782415, Example 7 BDBM127634
BDBM50318856 3-(1-benzylpiperidin-4-yl)-1-(1-phenyl-1,2,3,4-tetrahydroquinolin-7-yl)propan-1-one CHEMBL1084254
BDBM3373 Imidazopyridazine 37 ( 1RS)-2-Chloro-5-methyl-alpha-phenyl-7-imidazo[1,5-b]pyridazineheptanol Hydrochloride 7-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}-1-phenylheptan-1-ol
BDBM592598 N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-1-(4- cyclopropyl-2-pyrimidinyl)-N-methyl-2,3- dihydro-1H-indole-5-carboxamide US11572374, Example 7-1
BDBM242744 US11731974, Compound 7 US20240199618, Compound 7 US10030025, Compound 7 US10836768, Cpd no 7 US9987274, Compound 7 US9422299, 7
7-methoxy-1-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]-2-naphthol BDBM72646 7-methoxy-1-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]naphthalen-2-ol cid_2451535 7-methoxy-1-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]-2-naphthalenol MLS000760157 SMR000368586
1-(4-methoxyphenyl)-2-methyl-3-nitro-7-(1-piperidinylmethyl)-1H-indol-6-ol hydrochloride MLS000530226 1-(4-methoxyphenyl)-2-methyl-3-nitro-7-(1-piperidinylmethyl)-6-indolol;hydrochloride 1-(4-methoxyphenyl)-2-methyl-3-nitro-7-(piperidinomethyl)indol-6-ol;hydrochloride 1-(4-methoxyphenyl)-2-methyl-3-nitro-7-(piperidin-1-ylmethyl)indol-6-ol;hydrochloride BDBM54194 cid_2834628 SMR000135203
1-[(2S)-7-Methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H-spiro[1,8-naphthyridine-2,3'-pyrrolidin]-1'-yl]-2-[4-(trifluoromethyl)phenyl]propan-1-one, DIAST-1 (7) and 1-[(2S)-7-Methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H-spiro[1,8-naphthyridine-2,3'-pyrrolidin]-1'-yl]-2-[4-(trifluoromethyl)phenyl]propan-1-one, DIAST-2 (8) BDBM726749 US20250084084, Example 7
1-[(2S)-7-Methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H-spiro[1,8-naphthyridine-2,3'-pyrrolidin]-1'-yl]-2-[4-(trifluoromethyl)phenyl]propan-1-one, DIAST-1 (7) and 1-[(2S)-7-Methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H-spiro[1,8-naphthyridine-2,3'-pyrrolidin]-1'-yl]-2-[4-(trifluoromethyl)phenyl]propan-1-one, DIAST-2 (8) US12187727, Example 7 BDBM711470
MLS000071265 7-methyl-1-[(phenylmethyl)amino]-3-(1-piperidinyl)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile BDBM77972 1-(benzylamino)-7-methyl-3-piperidin-1-yl-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile 1-(benzylamino)-7-methyl-3-piperidino-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile SMR000039514 7-methyl-1-[(phenylmethyl)amino]-3-piperidin-1-yl-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile cid_658604
cid_658540 1-(benzylamino)-7-ethyl-3-piperidino-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile SMR000039582 1-(benzylamino)-7-ethyl-3-piperidin-1-yl-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile 7-ethyl-1-[(phenylmethyl)amino]-3-(1-piperidinyl)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile 7-ethyl-1-[(phenylmethyl)amino]-3-piperidin-1-yl-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile MLS000071249 BDBM41295
BDBM581463 (2s,4s)-2-(2-Phenyl-7-azaspiro[3.5]nonane-7-carbonyl)-7-oxa-5- azaspiro[3.4]octan-6-one US11505546, Example 1
BDBM582476 US11518767, Example 1 5-(2-aminobenzoxazol-5-yl)-7-isobutyl-7-methyl-6, 7-dihydro-5H-pyrrolo[3,2-d]pyrimidin-4-ylamine
CHEMBL389902 BDBM50213121 US9492405, (S)-7 US10925840, Compound (S)-7 (S)-(+)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-benzenediol US9492405, 26 US10617654, Compound (S)-7
US9492405, (R)-7 CHEMBL229620 (R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-benzenediol US9492405, 25 BDBM50213119 US10617654, Compound (R)-7 US10925840, Compound (R)-7
3-(4-Chloro-3-fluorophenyl)-N-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazine-2-carboxamide (7) US9598421, Example 7 US10669279, Example 7 BDBM285534 US10077269, Example 7
N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-N,1-dimethyl- 3-(6-methyl-2-pyridinyl)-1H-indazole-6- carboxamide BDBM592745 US11572374, Example 7-7
BDBM646167 N-((R)-1-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1]heptane-7- carbonyl)-1-cyclopropyl-7-methoxy- 1H-benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-indol-6- yl)ethyl)-2,2-difluorocyclopropane- 1-carboxamide US11878965, Example 152
N-((R)-1-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1]heptane-7- carbonyl)-7-methoxy-1-methyl-1H- benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-indol-6- yl)ethyl)-3,3-difluoroazetidine-1- carboxamide US11878965, Example 238 BDBM646247
US20250163066, Compound 6 1-(7-cyclopentylpyrazolo[1,5-a]pyrimidin-6-yl)-3-[6-[1-[7-[4-[2-(2,6-dioxo-3- piperidyl)-1-oxo-isoindolin-5-yl]piperazin-1-yl]-7-oxo-heptyl]triazol-4-yl]-5-methyl-3- pyridyl]urea BDBM743249
1-(3,4-Dichloro-benzyl)-3-(7-hydroxy-naphthalen-1-yl)-urea BDBM50138514 CHEMBL358953
1-(3-Chlorophenyl)-3-(3-(4-methylpiperazin-1-yl)propyl)urea (7) BDBM189349
1-(4-{[7-(1-methyl-1H-pyrazol-4-yl)- BDBM518382 US11111242, Example 218
1-(5-(3-fluorophenyl)oxazol-2-yl)-7-phenylheptan-1-one BDBM50204549 CHEMBL387376
1-(5-(4-aminophenyl)oxazol-2-yl)-7-phenylheptan-1-one BDBM50204566 CHEMBL219955
1-(5-(4-nitrophenyl)oxazol-2-yl)-7-phenylheptan-1-one BDBM50204530 CHEMBL373814
1-(7-Hydroxy-naphthalen-1-yl)-3-(3-trifluoromethyl-benzyl)-urea CHEMBL151446 BDBM50138506
1-[4-(carboxycarbonyl)phenyl]triaz-2-yn-2-ium-1-ide (7) BDBM124222
1-[7-(4-amino-1-quinoliniumylmethyl)-9H-2-fluorenylmethyl]-4-quinoliniumamine CHEMBL6356 BDBM50084846
1-cyclohexyl-4-[3-(7-methoxynaphthalen-1-yl)propyl]piperazine hydrochloride BDBM50219753 CHEMBL538089
3,3-dimethyl-1-[3-(7-methoxynaphthalen-1-yl)propyl]piperidine hydrochloride BDBM50219749 CHEMBL535636
4-[(1E)-oct-1-en-1-yl]benzoate BDBM23438 benzoic acid derivative, 7
7-(1-(1H-imidazol-1-yl)ethyl)-9H-fluoren-2-ol BDBM50272156 CHEMBL505550
BDBM235635 (E)-1-(2,4-dihydroxyphenyl)-3-(2-nitrophenyl)-2-propen-1-one (7)
BDBM3871 1-phenyl-1H-1,3-benzodiazole-7-carboxylic acid 1-Phenylbenzimidazole deriv. 88
BDBM3872 methyl 1-phenyl-1H-1,3-benzodiazole-7-carboxylate 1-Phenylbenzimidazole deriv. 89
BDBM391716 N-[(2R)-3-(7-methyl-1H- US10300056, Example 1 US10888561, Example 1
BDBM50013018 2-Diazo-1-(7-dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl)-ethanone CHEMBL353334
BDBM50054114 1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperidine CHEMBL135738
BDBM50075051 CHEMBL3360855 EPZ005687 US9637472, Compound C-1 US9175331, 7 US10273223, Compound C-1
BDBM50138504 1-(3,4-Difluoro-benzyl)-3-(7-hydroxy-naphthalen-1-yl)-urea CHEMBL342300
BDBM50204483 CHEMBL373606 7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-1-one
BDBM50204526 1-(5-(4-hydroxyphenyl)oxazol-2-yl)-7-phenylheptan-1-one CHEMBL220066
BDBM50204546 CHEMBL220844 1-(5-(2-aminophenyl)oxazol-2-yl)-7-phenylheptan-1-one
BDBM50204557 CHEMBL375303 1-(5-(3-aminophenyl)oxazol-2-yl)-7-phenylheptan-1-one
BDBM50204559 CHEMBL219674 1-(5-(3-nitrophenyl)oxazol-2-yl)-7-phenylheptan-1-one
BDBM50204571 1-(5-(2-hydroxyphenyl)oxazol-2-yl)-7-phenylheptan-1-one CHEMBL222415
BDBM50272210 1-[1-(7-Fluoro-9H-fluoren-2-yl)-ethyl]-1H-imidazole CHEMBL501460
BDBM50272212 CHEMBL454217 2-(1-(1H-Imidazol-1-yl)ethyl)-7-fluoro-9H-carbazole
BDBM50276987 7-(naphthalen-1-ylsulfonyl)-2-(piperazin-1-yl)benzo[d]oxazole CHEMBL459987
CHEMBL111558 1-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-pyrrolidin-2-one BDBM50037220
CHEMBL1277466 7-(4-methylpiperazin-1-yl)-3-(naphthalen-1-ylsulfonyl)-1H-indazole BDBM50330513
CHEMBL1289498 (S)-tert-butyl 1-(cyclopentylamino)-7-hydroxy-1-oxoheptan-2-ylcarbamate BDBM50331105
CHEMBL147028 BDBM50138512 1-(2,4-Dichloro-benzyl)-3-(7-hydroxy-naphthalen-1-yl)-urea
CHEMBL147068 1-(7-Hydroxy-naphthalen-1-yl)-3-(4-trifluoromethoxy-benzyl)-urea BDBM50138518
CHEMBL148920 1-(7-Hydroxy-naphthalen-1-yl)-3-(4-trifluoromethyl-benzyl)-urea BDBM50138515
CHEMBL1774562 N-(4-(7-((Adamantan-1-ylmethoxy)heptyl)phenyl)-1-carbamimidoylcyclopropanecarboxamide Hydrochloride BDBM50343820
CHEMBL19442 BDBM50125637 Cyclopropyl-[4-(7-methoxy-naphthalen-1-yl)-piperazin-1-yl]-methanone
CHEMBL19512 BDBM50125640 4-(7-Methoxy-naphthalen-1-yl)-piperazine-1-carboxylic acid ethylamide
CHEMBL220309 1-(5-(4-methoxyphenyl)oxazol-2-yl)-7-phenylheptan-1-one BDBM50204563
CHEMBL220518 1-(5-(3-methoxyphenyl)oxazol-2-yl)-7-phenylheptan-1-one BDBM50204531
CHEMBL222463 1-(5-(3-hydroxyphenyl)oxazol-2-yl)-7-phenylheptan-1-one BDBM50204542
CHEMBL222614 1-(5-(4-fluorophenyl)oxazol-2-yl)-7-phenylheptan-1-one BDBM50204521
CHEMBL223693 BDBM50204570 1-(5-(2-fluorophenyl)oxazol-2-yl)-7-phenylheptan-1-one
CHEMBL223694 BDBM50204476 1-(5-(2-methoxyphenyl)oxazol-2-yl)-7-phenylheptan-1-one
CHEMBL299822 BDBM50090527 1-(Naphthalene-1-sulfonyl)-6-(octahydro-indolizin-7-yl)-1H-indole
CHEMBL375405 BDBM50206436 3-hydroxy-4-(naphthalen-1-yldiazenyl)-7-nitronaphthalene-1-sulfonic acid
CHEMBL375573 1-(5-(2-nitrophenyl)oxazol-2-yl)-7-phenylheptan-1-one BDBM50204554
CHEMBL461544 BDBM50247137 7-phenyl-1-(4-(trifluoromethyl)oxazol-2-yl)heptan-1-one
CHEMBL467141 BDBM50261885 1-(2-Methyl-2H-tetrazol-5-yl)-7-phenylheptan-1-one
CHEMBL52790 1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine BDBM50048872
CHEMBL535634 1-cyclohexyl-4-[3-(7-hydroxynaphthalen-1-yl)propyl]piperazine hydrochloride BDBM50219755
CHEMBL558572 3,3-dimethyl-1-[3-(7-hydroxynaphthalen-1-yl)propyl]piperidine hydrochloride BDBM50219757
N-[1-(7-chloro-1-benzothien-2-yl)ethyl]-N-hydroxyurea BDBM50058568 CHEMBL300783
US20240217978, Example 275 BDBM683619 (S)-1-(4-(1-(7-amino-2-(furan-2-
BDBM300299 US9593110, 7-7
US8592457, 7-7 BDBM106972
US9302996, 7-7 BDBM220892
BDBM592569 US11572374, Example 1-61 Mixture of two diastereomers: (3R)-1-(3- chlorophenyl)-N-(7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-5-oxo-3- pyrrolidinecarboxamide, and (3S)-1-(3- chlorophenyl)-N-(7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-5-oxo-3- pyrrolidinecarboxamide
MLS001166643 cid_2303617 3-amino-2-methyl-7-nitro-4-phenylisoquinolin-1-one 3-amino-2-methyl-7-nitro-4-phenyl-1-isoquinolinone BDBM90904 3-azanyl-2-methyl-7-nitro-4-phenyl-isoquinolin-1-one 3-amino-2-methyl-7-nitro-4-phenyl-isocarbostyril SMR000595988
MLS001179359 7-chloro-4-[4-(2-chloroethyl)piperazino]quinoline;hydrochloride SMR000477401 7-chloranyl-4-[4-(2-chloroethyl)piperazin-1-yl]quinoline;hydrochloride cid_23723196 7-chloro-4-[4-(2-chloroethyl)-1-piperazinyl]quinoline;hydrochloride 7-chloro-4-[4-(2-chloroethyl)piperazin-1-yl]quinoline;hydrochloride BDBM78955
US11572374, Example 1-62 BDBM592570 Mixture of two diastereomers: (3R)-1-(3- bromophenyl)-N-(7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-5-oxo-3- pyrrolidinecarboxamide, and (3S)-1-(3- bromophenyl)-N-(7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-5-oxo-3- pyrrolidinecarboxamide
US11572374, Example 1-63 Mixture of two diastereomers: (3R)-1-(3- chlorophenyl)-N-(7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-oxo-3- pyrrolidinecarboxamide, and (3S)-1-(3- chlorophenyl)-N-(7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-oxo-3- pyrrolidinecarboxamide BDBM592571
BDBM230871 US10045974, 7 US9346797, 7 US10603310, Compound 7
US10238633, Example 7 US8987249, 7 BDBM150333 US9713606, 7
US10487111, Example 7. US9694018, 7 BDBM77051 US10093697, 7.
US10640503, Example 7 BDBM103893 US9695168, 7 US10047086, 7
US20240317756, Compound 7 US9278100, 7 US9181263, 7 BDBM191612
US8981112, 7 BDBM150700 US9949975, Example 7 US9526727, 7
US9227969, 7 BDBM200379 US9629836, 7 US10011599, Example 7
US9708313, 7 US9181249, 7 BDBM190896 US10077266, Example 7
CHEMBL467368 7-phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)heptan-1-one BDBM50261710 7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-heptan-1-one
BDBM221686 US9314464, 7 US9593100, Compound 7 US10568884, Cpd 7 USRE49556, Compound 7
BDBM259408 US11673868, Example 7 US11180460, Example 7 US10457647, Example 7 US9512084, 7
US10034939, Example 7 US10967060, Example 7 US9320732, 7 BDBM223005 US11207302, Example 7
US10106559, Example 7 US9850258, Example 7 US9334290, 7 BDBM230085 US10435415, Example 7
US10167273, Example 7 US9475795, 7 BDBM250528 US11512066, Example 7 US10544126, Example 7
US10213433, Compound 7 US20240043404, Example 7 US11369599, Compound 7 US9174982, 7 BDBM189461
US10632171, Peptide No. 7 US8846601, 7 US9458201, 7 US10179804, Example 7 BDBM135622
US10683295, Compound 7 US10941151, Compound 7 US10065961, Compound 7 US9475814, 7 BDBM251909
BDBM352203 US10239868, Entry 7 US20240425487, Entry 7 US9802924, Entry 7 US10676464, Entry 7 US10287274, Entry 7
BDBM465218 US11560376, Compound 7 US11419869, Compound 7 US20230271960, Compound 7 US10793564, Compound 7 US20230293519, Compound 7
US10035797, Compound 7 US9630965, Compound 7 US10844056, Compound 7 BDBM279667 US11560377, Compound 7 US10428068, Compound 7
US10106527, Compound 7 BDBM293421 US10544128, Compound 7 US11548872, Compound 7 US9951048, Compound 7 US20230286945, Compound 7
US10689414, Compound 7 US9850277, Compound 7 BDBM363514 US10640534, Compound 7 US10717764, Compound 7 US11021515, Compound 7
US10781209, Example 7 US11702416, Example 7 BDBM391507 US10472358, Example 7 US9957268, Example 7 US11059821, Example 7
US11648243, Example 7 US10144734, Example 7 US10881652, Example 7 US10441581, Example 7 BDBM304991 US10172845, Example 7
6-Imidazol-1-yl-7-nitro-1,4-dihydro-quinoxaline-2,3-dione BDBM50030674 CHEMBL13260 YM-90K 6-(1H-1-imidazolyl)-7-nitro-1,2,3,4-tetrahydro-2,3-quinoxalinedione 6-(1H-imidazol-1-yl)-7-nitroquinoxaline-2,3(1H,4H)-dione
cid_2997591 7-(2,3-dihydroindol-1-ylmethyl)-[1,3]thiazolo[3,2-a]pyrimidin-5-one 7-(2,3-dihydroindol-1-ylmethyl)-5-thiazolo[3,2-a]pyrimidinone 7-(indolin-1-ylmethyl)thiazolo[3,2-a]pyrimidin-5-one MLS000081688 SMR000062931 BDBM128124
BDBM40089 MLS000117134 7-[4-(2-furoyl)piperazine-1-carbonyl]-2-(4-methoxyphenyl)isoindolin-1-one 7-[[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-oxomethyl]-2-(4-methoxyphenyl)-3H-isoindol-1-one 7-[4-(furan-2-ylcarbonyl)piperazin-1-yl]carbonyl-2-(4-methoxyphenyl)-3H-isoindol-1-one 7-[4-(furan-2-carbonyl)piperazine-1-carbonyl]-2-(4-methoxyphenyl)-3H-isoindol-1-one SMR000094087 cid_5307358
1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4,4a,8a-tetrahydro-quinoline-3-carboxylic acid (norfloxacin) Chibroxin (norfloxacin)1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid(Norfloxacin) CHEMBL9 1-ethyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid (Norfloxacin) 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid(1-norfloxacin) NORFLOXACIN Noroxin 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (NFLX)1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid BDBM50045000 MK-366
2-(5-((Cyclopropylmethyl)(4-fluoronaphthalen-1-yl)amino)-3-methoxypicolinoyl)cyclopropanecarboxylic acid US9657001, 7 US20160326143, 7 BDBM223232
5-(1-benzylpiperidin-4-yl)-7-ethyl-4- oxa-7-azaspiro[2.5]octane US10421750, Example 14 BDBM413882
BDBM110109 US8609678, 2-(3,4-dihydroquinolin-1(2H)-yl)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide [162]
BDBM110125 US8609678, (R)-N-(7-(hydroxyamino)-7-oxoheptyl)-2-(3-hydroxypiperidin-1-yl)pyrimidine-5-carboxamide [178]
BDBM270890 7-(benzenesulfonyl)-4-(piperidin-1-yl)-5H-pyrrolo[3,2-d]pyrimidin-6-amine US10059713, Example 7
BDBM3367 7-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}-1-phenylheptan-2-one Imidazopyridazine 15e
BDBM413879 7-ethyl-5-(1-phenethylpiperidin-4-yl)- 4-oxa-7-azaspiro[2.5]octane US10421750, Example 11
BDBM413912 US10421750, Example 48 7-ethyl-5-(1-isopentylpiperidin-4- yl)-4-oxa-7-azaspiro[2.5]actane
BDBM67477 2-chloro-7-methoxy-10H-phenothiazine cid_350929 SR-03000000698-1 2-chloranyl-7-methoxy-10H-phenothiazine
MLS000113706 BDBM48621 cid_2929318 SMR000109600 2-(4-methoxyphenoxy)-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)ethanone
N-ethyl-2-(7-fluoro-1H-indol-3-yl)-N- methylethan-1-amine BDBM693487 US20240286998, Compound 7
US10851083, Example 7 US11618744, Example 7 1-(5-Methoxy-1H-benzoimidazol-2-yl)-1H-pyrazole-4- BDBM475395
US9856263, 7 4-[4-(4, 6-Dimethylpyrimidin-5-yl)phenoxy]pyrazolo[1, 5-a]pyrazine (7) BDBM364287
(+)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one (+)-marmesin (7S)-marmesin (2S)-2-(1-hydroxy-1-methylethyl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one (S)-marmesin BDBM50250917 CHEMBL442813 S-(+)-marmesin (S)-(+)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one (S)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one Marmesin
1-((R)-2-(2-(5-((1R,2R,4S)-2-amino- 7-azabicyclo[2.2.1]heptane-7- carbonyl)-7-methoxy-1-methyl-1H- benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-pyrrolo[2,3- b]pyridin-6-yl)pyrrolidin-1-yl)ethan- 1-one US11878965, Example 247 BDBM646256
BDBM646222 US11878965, Example 207 N-((R)-1-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1]heptane-7- carbonyl)-7-methoxy-1-methyl-1H- benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-pyrrolo[2,3- b]pyridin-6-yl)ethyl)-1- (trifluoromethyl)cyclopropane-1- carboxamide
BDBM7501 4-{(Z)-[4,6-dihydroxy-7-(1-methylpiperidin-4-yl)-3-oxo-1-benzofuran-2(3H)-ylidene]methyl}benzenesulfonamide CHEMBL48362 Benzofuranone deriv. 7 4-{[(2Z)-4,6-dihydroxy-7-(1-methylpiperidin-4-yl)-3-oxo-2,3-dihydro-1-benzofuran-2-ylidene]methyl}benzene-1-sulfonamide
CHEMBL88275 BDBM50020299 (R-isomer)7-[3,5-Dihydroxy-2-(3-hydroxy-7-phenyl-hept-1-enyl)-cyclopentyl]-hept-5-enoic acid (S-isomer)7-[3,5-Dihydroxy-2-(3-hydroxy-7-phenyl-hept-1-enyl)-cyclopentyl]-hept-5-enoic acid
cid_22588261 BDBM69947 3-(2-besylacetyl)-7-methoxy-coumarin MLS001028523 3-[2-(benzenesulfonyl)-1-oxoethyl]-7-methoxy-1-benzopyran-2-one SMR000634146 3-[2-(benzenesulfonyl)acetyl]-7-methoxychromen-2-one 7-methoxy-3-[2-(phenylsulfonyl)ethanoyl]chromen-2-one
[2-(2-methoxyethyl)-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxoisoquinolin-7-yl] quinoxaline-2-carboxylate cid_16759706 quinoxaline-2-carboxylic acid [6,8-diketo-2-(2-methoxyethyl)-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-7-isoquinolyl] ester MLS000438667 SMR000452716 BDBM93631 2-quinoxalinecarboxylic acid [2-(2-methoxyethyl)-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxo-7-isoquinolinyl] ester [2-(2-methoxyethyl)-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-bis(oxidanylidene)isoquinolin-7-yl] quinoxaline-2-carboxylate
[2-(4-hydroxybutyl)-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxoisoquinolin-7-yl] quinoxaline-2-carboxylate 2-quinoxalinecarboxylic acid [2-(4-hydroxybutyl)-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-6,8-dioxo-7-isoquinolinyl] ester quinoxaline-2-carboxylic acid [2-(4-hydroxybutyl)-6,8-diketo-3-[(E)-3-methoxyprop-1-enyl]-7-methyl-7-isoquinolyl] ester cid_16745649 MLS000438664 BDBM93594 [3-[(E)-3-methoxyprop-1-enyl]-7-methyl-2-(4-oxidanylbutyl)-6,8-bis(oxidanylidene)isoquinolin-7-yl] quinoxaline-2-carboxylate SMR000452713
BDBM728219 US20250092039, Compound 3 Preparation of (S)-3-(5-(4-((7-((1-(((4-(((1-(dimethylamino)cyclobutyl)methyl) amino)-7-(8-ethyl-7-fluoro-3-hydroxynaphthalen-1-yl)-8-fluoropyrido[4,3-d]pyrimidin-2-yl)oxy)methyl)cyclopropyl)methyl)-7-azaspiro[3.5]nonan-2-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione 
cid_786636 7-methoxy-2-methyl-3-(1-phenyl-4-pyrazolyl)-1-benzopyran-4-one SMR000137066 BDBM37830 7-methoxy-2-methyl-3-(1-phenylpyrazol-4-yl)chromen-4-one 7-methoxy-2-methyl-3-(1-phenylpyrazol-4-yl)chromone MLS000532125 7-methoxy-2-methyl-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-4-one
BDBM497349 1-Ethyl-7-[[(1S)-1-[4-[3- methyl-1-(4-prop-2- enoylpiperazin-1- yl)butyl]phenyl]ethyl]amino]- 4H-pyrimido[4,5- d][1,3]oxazin-2-one, isomer 1 US11001596, Example 7
1-(7-(7-fluoro-2-((1-(methylsulfonyl)piperidin-4-yl)amino)quinazolin-8-yl)-2,7-diazaspiro[4.4]nonan-2-yl)ethan-1-one US20240092761, Compound 45 BDBM659349
7-(2-Chloro-4-fluoro-phenylsulfamoyl)-cyclohept-1-enecarboxylic acid ethyl ester CHEMBL375048 ethyl 7-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohept-1-ene-1-carboxylate BDBM50177129
BDBM749836 (7R)-7-amino-7-[1-(2-methyl- 2H-indazol-5-yl)-1H-pyrazol- 3-yl]-1-(1,3-oxazol-2- yl)heptan-1-one US12331044, Example 127
BDBM749837 (7S)-7-amino-7-[1-(2-methyl- 2H-indazol-5-yl)-1H-pyrazol- 3-yl]-1-(1,3-oxazol-2- yl)heptan-1-one US12331044, Example 128
US10676434, Example 171 US11053197, Example 171 US10266491, Example 171 BDBM377478 4-(1-acryloyl-1-azaspiro[4.4] nonan-7-yl)-3-fluoro-7- (trifluoromethyl)-9H- carbazole-1-carboxamide
3-((6-Chloro-1-(2-(2-cyano-7-azaspiro[3.5]nonan-7-yl)-2-oxoethyl)-7-fluoro-2-methyl-1H-indol-3-yl)thio)benzoic acid BDBM362952 US9850203, Compound 1-19
4-methoxy-7-methyl-2-(1-pyrrolidinyl)-1,3-benzothiazole MLS000045499 SMR000027256 4-methoxy-7-methyl-2-pyrrolidino-1,3-benzothiazole 4-methoxy-7-methyl-2-pyrrolidin-1-yl-1,3-benzothiazole cid_3240926 BDBM78007
BDBM749789 US12331044, Example 80 (S)-7-(5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl)-1-(oxazol-2-yl)-7-((tetrahydro-2H-pyran-4-yl)amino)heptan-1-one
BDBM749803 (S)-2-(dimethylamino)-N-(1-(5-(2-ethyl-7-methoxy-1-oxo-1,2-dihydroisoquinolin-6-yl)-1H-imidazol-2-yl)-7-(isoxazol-3-yl)-7-oxoheptyl)acetamide US12331044, Example 94
BDBM749805 US12331044, Example 96 (S)-2-(dimethylamino)-N-(1-(5-(2-ethyl-7-methoxy-1-oxo-1,2-dihydroisoquinolin-6-yl)-1H-imidazol-2-yl)-7-(oxazol-2-yl)-7-oxoheptyl)acetamide
N-[(1S)-1-[5-(7-methoxy-2- methylquinolin-6-yl)-1H- imidazol-2-yl]-7-(1,3-oxazol-2- yl)-7-oxoheptyl]-2-(2- oxopiperazin-1-yl)acetamide BDBM749867 US12331044, Example 159
US12331044, Example 160 BDBM749868 N-[(1S)-1-[5-(7-methoxy-2- methylquinolin-6-yl)-1H- imidazol-2-yl]-7-(1,3-oxazol-2- yl)-7-oxoheptyl]-2-(1H-pyrazol-1- yl)acetamide
US12331044, Example 162 BDBM749870 N-[(1S)-1-[5-(7-methoxy-2- methylquinolin-6-yl)-1H- imidazol-2-yl]-7-(1,3-oxazol-2- yl)-7-oxoheptyl]-2-(1H-pyrrol-1- yl)acetamide
(3S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-1-(3,5- dichlorophenyl)-3-pyrrolidinecarboxamide US11572374, Example 28-1 BDBM592912
1-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-3-(1-(2,3- dichlorophenyl)ethyl)urea US11572374, Example 23-5 BDBM592894
16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10,12,14-hexaene-1-carboxamide(ADCI) 16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10,12,14-hexaene-1-carboxamide BDBM50013494 CHEMBL10861
4-(1H-benzotriazol-1-yl)-N-((1R,2R,4S)-7- cyano-7-azabicyclo[2.2.1]heptan-2- yl)benzamide US11572374, Example 1-20 BDBM592528
7-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine BDBM50161642 CHEMBL181672 (1R,S)-7-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-carboxylic acid methyl ester BDBM50030002 (R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-carboxylic acid methyl ester CHEMBL86648
BDBM50076227 CHEMBL28817 (1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]pyridazine-1-carboxylic acid ((S)-4-guanidino-1-phenethylaminooxalyl-butyl)-amide
BDBM535727 US11236092, Example 7 7'-(4-(Benzyloxy)phenyl)-2'- oxo-1',4'-dihydro-2'H- spiro$#9484;pyrrolidine-3,3'- quinoline$#9488;-1-carbonitrile
BDBM592921 (3S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-1-(3- methylphenyl)-3-pyrrolidinecarboxamide US11572374, Example 30-1
BDBM749725 US12331044, Example 16 (S)-7-amino-1-(oxazol-2-yl)-7-(5-(quinolin-6-yl)-1H-imidazol-2-yl)heptan-1-one
BDBM749737 (S)-7-amino-7-(5-(2-methoxypyridin-3-yl)oxazol-2-yl)-1-(oxazol-2-yl)heptan-1-one US12331044, Example 28
BDBM749843 (7S)-7-amino-7-[5-(2,5- difluorophenyl)-1H-imidazol-2-yl]- 1-(1,3-oxazol-2-yl)heptan-1-one US12331044, Example 135
BDBM749844 (7S)-7-amino-7-[5-(2,3- difluorophenyl)-1H-imidazol-2-yl]- 1-(1,3-oxazol-2-yl)heptan-1-one US12331044, Example 136
CHEMBL28365 (1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]pyridazine-1-carboxylic acid ((S)-1-benzylaminooxalyl-4-guanidino-butyl)-amide BDBM50076224
CHEMBL314909 BDBM50081003 7-Methoxy-naphthalene-2-sulfonic acid [(S)-1-(1-amino-6-methoxy-isoquinolin-7-ylmethyl)-2-oxo-pyrrolidin-3-yl]-amide
CHEMBL316050 BDBM50030019 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-carboxylic acid methyl ester (S)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-carboxylic acid methyl ester
Pyridine-substituted naphthalene 14 3-(1-Chloro-7-methoxy-2-naphthyl)pyridine 3-(1-chloro-7-methoxynaphthalen-2-yl)pyridine US9271963, 14 BDBM8913
US11572374, Example 1-86 BDBM592663 N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-methyl-1- phenyl-3-pyrrolidinecarboxamide
US11572374, Example 23-1 BDBM592890 1-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-3-(2-(2,5- dichlorophenyl)ethyl)urea
US8722896, (-)-(3R)-1-(1-Methyl-indol-7- ylmethyl)-N-(9-chloro-3,4- dihydro-2H-1,5-benzodioxepin- 7-ylmethyl)-N- isobutylpyrrolidine-3- carboxamide BDBM121048
US9962388, Compound Example 7 1-(4-((4-amino-2-butoxy-5H-pyrrolo[3,2-d]pyrimidine-7-1)methyl)benzyl)pyrrolidine-3-ol BDBM392994