US9611252, Example 132 N-((1-aminoisoquinolin-6-yl)methyl)-2-((3- methylisoquinolin-6-yl)methyl)isonicotinamide BDBM283480 US11021463, Example 132 US10266515, Example 132 US10023557, Example 132 US10308637, Example 132
US10723734, Example 132 BDBM311276 US9902722, Example 132 US10351563, Example 132 (S)-1-((4-(difluoromethyl)-6-(6-fluoroquinolin-4-yl)pyridin-3-yl)oxy)-2,4-dimethylpentan-2-amine US10155760, Example 132 US10981910, Example 132 US10544120, Example 132
BDBM101159 US8524917, 132
BDBM101635 US8530652, 132
BDBM103155 US8541407, 132
BDBM103707 US8563553, 132
BDBM104712 US8569308, 132
BDBM109411 US8604061, 132
BDBM111137 US9695179, 132
BDBM115314 US8637500, 132
BDBM118704 US9682940, 132
BDBM119575 US8680275, 132
BDBM121693 US8722692, 132
BDBM123619 US8748624, 132
BDBM125737 US8772305, 132
BDBM126108 US8779142, 132
BDBM126648 US8785638, 132
BDBM128550 US8796244, 132
BDBM128962 US8802711, 132
BDBM129490 US8802673, 132
BDBM130275 US8815840, 132
BDBM131722 US8835470, 132
BDBM134130 US8846689, 132
BDBM134234 US8846673, 132
BDBM134669 US8846698, 132
BDBM136501 US8865726, 132
BDBM140072 US8901315, 132
BDBM140701 US8912224, 132
BDBM141238 US8653100, 132
BDBM142539 US8933224, 132
BDBM143931 US8969325, 132
BDBM144381 US8969358, 132
BDBM145353 US8952169, 132
BDBM146097 US8957068, 132
BDBM147301 US8957093, 132
BDBM150943 US8981106, 132
BDBM151697 US8987445, 132
BDBM151938 US8987457, 132
BDBM152046 US8987473, 132
BDBM152397 US8993565, 132
BDBM153615 US8999975, 132
BDBM155700 US9012651, 132
BDBM157293 US9023865, 132
BDBM158424 US9029393, 132
BDBM159990 US9040528, 132
BDBM161673 US9682976, 132
BDBM163505 US9062048, 132
BDBM164321 US9688615, 132
BDBM167046 US9073876, 132
BDBM169599 US9079880, 132
BDBM169783 US9073940, 132
BDBM170413 US9079929, 132
BDBM173030 US9096579, 132
BDBM175583 US9688680, 132
BDBM178573 US9125913, 132
BDBM180247 US9133157, 132
BDBM181929 US9145380, 132
BDBM182431 US9145392, 132
BDBM183512 US9145354, 132
BDBM184262 US9150577, 132
BDBM185479 US9156845, 132
BDBM186469 US9163021, 132
BDBM187559 US9169252, 132
BDBM188866 US9169260, 132
BDBM189912 US9174997, 132
BDBM189979 US9175003, 132
BDBM193212 US9193736, 132
BDBM194216 US9200001, 132
BDBM196027 US9206199, 132
BDBM197865 US9216988, 132
BDBM199067 US9221832, 132
BDBM201701 US9233979, 132
BDBM203575 US9221809, 132
BDBM204013 US9242996, 132
BDBM205663 US9255090, 132
BDBM206219 US9255110, 132
BDBM206393 US9260425, 132
BDBM206812 US9249163, 132
BDBM208434 US9266835, 132
BDBM214070 US9283222, 132
BDBM214933 US9296734, 132
BDBM220543 US9296741, 132
BDBM221017 US9302996, 132
BDBM221206 US9303012, 132
BDBM223910 US9328112, 132
BDBM229390 US9556135, 132
BDBM229805 US9334269, 132
BDBM231746 US9340517, 132
BDBM233525 US9351965, 132
BDBM236965 US9388189, 132
BDBM238502 US9394297, 132
BDBM239945 US9403767, 132
BDBM241037 US9409892, 132
BDBM244523 US9428502, 132
BDBM245677 US9428508, 132
BDBM247903 US9434719, 132
BDBM249704 US9447038, 132
BDBM250828 US9452986, 132
BDBM252551 US9458172, 132
BDBM253172 US9458171, 132
BDBM255173 US9475817, 132
BDBM255381 US9481682, 132
BDBM257114 US9493435, 132
BDBM257288 US9493440, 132
BDBM259619 US9505749, 132
BDBM264410 US9714247, 132
BDBM302220 US9598415, 132
BDBM302991 US9598440, 132
BDBM327591 US9663469, 132
BDBM389813 US9951063, 132
BDBM5275 US8530490, 132
BDBM77464 US9695118, 132
BDBM99631 US8501936, 132
US10047096, 132 BDBM227871
US8481733, 132 BDBM98320
US8486940, 132 BDBM64757
US8487093, 132 BDBM98764
US8501750, 132 BDBM99962
US8507533, 132 BDBM100825
US8530648, 132 BDBM102261
US8569281, 132 BDBM105115
US8575145, 132 BDBM104255
US8575186, 132 BDBM104369
US8575201, 132 BDBM104641
US8592455, 132 BDBM106932
US8614223, 132 BDBM139346
US8623889, 132 BDBM112134
US8633206, 132 BDBM113213
US8637532, 132 BDBM116451
US8648092, 132 BDBM117201
US8674113, 132 BDBM118875
US8697911, 132 BDBM119967
US8703768, 132 BDBM120532
US8772323, 132 BDBM180633
US8772480, 132 BDBM125314
US8778951, 132 BDBM126322
US8791131, 132 BDBM127374
US8802864, 132 BDBM128366
US8815926, 132 BDBM129853
US8822458, 132 BDBM130535
US8841312, 132 BDBM132386
US8841455, 132 BDBM132037
US8846601, 132 BDBM135747
US8846658, 132 BDBM134415
US8846699, 132 BDBM133814
US8846719, 132 BDBM133445
US8846746, 132 BDBM132862
US8853258, 132 BDBM135504
US8871934, 132 BDBM137539
US8912181, 132 BDBM140506
US8921389, 132 BDBM141675
US8940736, 132 BDBM142789
US8957074, 132 BDBM147092
US8962637, 132 BDBM148406
US8969341, 132 BDBM143519
US8975417, 132 BDBM150072
US9012443, 132 BDBM154124
US9012443, 132 BDBM154126
US9018214, 132 BDBM156081
US9029370, 132 BDBM158338
US9034866, 132 BDBM158657
US9056843, 132 BDBM162841
US9067871, 132 BDBM164654
US9067922, 132 BDBM165797
US9067949, 132 BDBM166275
US9073853, 132 BDBM166573
US9073870, 132 BDBM166836
US9073881, 132 BDBM167380
US9085555, 132 BDBM170704
US9120812, 132 BDBM178347
US9150526, 132 BDBM183879
US9150566, 132 BDBM184094
US9169224, 132 BDBM188443
US9187424, 132 BDBM201367
US9199947, 132 BDBM193633
US9216972, 132 BDBM197672
US9233953, 132 BDBM201169
US9234000, 132 BDBM200141
US9242970, 132 BDBM202984
US9260439, 132 BDBM207155
US9265773, 132 BDBM208187
US9266876, 132 BDBM208665
US9266877, 132 BDBM209186
US9273033, 132 BDBM209830
US9278981, 132 BDBM213540
US9290451, 132 BDBM210384
US9290485, 132 BDBM212100
US9296745, 132 BDBM215576
US9302989, 132 BDBM217007
US9303023, 132 BDBM221435
US9315498, 132 BDBM222843
US9321756, 132 BDBM224877
US9328106, 132 BDBM227184
US9346798, 132 BDBM231385
US9353090, 132 BDBM234004
US9353104, 132 BDBM234827
US9365576, 132 BDBM236379
US9394285, 132 BDBM238045
US9394309, 132 BDBM239675
US9394331, 132 BDBM240870
US9403813, 132 BDBM240226
US9428504, 132 BDBM245382
US9434725, 132 BDBM248901
US9458110, 132 BDBM252061
US9458176, 132 BDBM252735
US9464044, 132 BDBM250495
US9481672, 132 BDBM255954
US9493446, 132 BDBM257662
US9499482, 132 BDBM258733
US9505762, 132 BDBM259764
US9675593, 132 BDBM168578
US9682955, 132 BDBM143501
US9693997, 132 BDBM70482
US9695170 132 BDBM109214
US9708253, 132 BDBM261473
US9708359, 132 BDBM263168
USRE46792, 132 BDBM389058
BDBM383849 US10550099, Compound I-132 US10280150, Cmpd No I-132
US10577336, Example 132 US10071974, Example 131 US10071974, Example 132 BDBM276020
BDBM404480 US11066365, Example 132 US11390584, Example 132 US10343992, Example 132 US10689345, Example 132 (R)-N-(1-cyanopyrrolidin- 3-yl)-5-(1-ethyl-1H- pyrazol-4-yl)-4- methylpicolinamide
US10730870, Example 129 BDBM454960 US10730870, Example 128 US10730870, Example 132 US11512083, Example 132
BDBM244380 US9550763, Compound I-132
BDBM323395 US9630956, Compound I-132
BDBM332843 US10196390, Compound I-132
BDBM375913 US9914731, Ex. No. 132
BDBM388435 US10294246, Compound No. 132
BDBM398403 US10323018, Compound I-132
BDBM464803 US10793563, Compound I-132
BDBM482065 US10913753, Compound I-132
BDBM482984 US10919885, Compound No. 132
BDBM50547892 CHEMBL4788313 US11377438, Example 132
BDBM408794 US10364238, Example 132 N-[(3-ethyl-2-fluorophenyl)methyl]-3-(methoxymethyl)-1-({4-[(2-oxopyridin-1- yl)methyl]phenyl}methyl)pyrazole-4-carboxamide US11001578, Example 132 US11084809, Example 132 US11198691, Example 132
US11352360, Example 132' US9884868, Example 132' BDBM282927 US10287295, Example 132' 6-(4-(4-fluorophenyl)-1-(3-hydroxypropyl)-1H- imidazol-5-yl)imidazo[1,2-b]pyridazine-3-carboxamide
US11618744, Example 132 US10851083, Example 132 BDBM475520 1-(5-Benzylamino-6-chloro-1H-benzoimidazol-2-yl)-1H-
US9708318, 132 US10251892, Example 132 US10632126, Example 132 US11173162, Example 132 BDBM262024 3-(2,6-difluoro-3,5-dimethoxyphenyl)-7-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(1-propyl-1H-pyrazol-4-yl)-3,4-dihydropyrido[4,3-d]pyrimidin-2(1H)-one
US11319287, Example 132 US10669234, Example 132 BDBM445193 (S)-2-(5-(2-cyanophenyl)- isoindoline-2-carbonyl)- pyrrolidine-1-carbonitrile
US9617225, Example 132 2-Chloro-4-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-benzamide BDBM316304 US10294218, Example 132
US10851110, Example 132 US11466017, Example 132 US10280171, Example 132 3-{6-[4-(amino- methyl)-4-methyl- piperidin-1-yl]-1H- pyrazolo[3,4-b]- pyrazin-3-yl}-2- chloroaniline BDBM384209
US10034861, Example 132 US10512632, Example 132 BDBM279101 US10806718, Example 132 US10766893, Example S132 US11634416, Example 132 5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidazol-4-yl)methyl]-1-[1-methylpropyl]pyrazolo[4,3-b]pyridin-7-amine,enantiomer 2
US11498926, Example 132 US9624241, Example 132 BDBM318588 Methyl 3-[7-(3,5-dimethylisoxazol-4-yl)-2-oxo-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazin-4-yl]pyridine-2-carboxylate US10464947, Example 132
US10450296, Example 132 BDBM376801 US11053215, Example 132 US9920032, Example 132 N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-5-fluoro-3-(2-(hydroxymethyl)morpholino)quinoline-8-carboxamide
US10738052, Example 132 BDBM388802 US11261191, Example 132 US9944645, 132 N-(1S)-1-[(Dimethylamino)carbonyl]-2,2-dimethylpropyl-2-fluoro-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide
US9944647, Example 132 BDBM389023 US10800779, Example 132 US11401272, Example 132 4-{8-[5-(difluoromethyl)-6- methylpyridin-3-yl]-5-[4- (dimethylamino)piperidin-1- yl]imidazo[1,2-c]pyrimidin-7- yl}benzonitrile
1-((7-amino-2- US20240217978, Example 132 BDBM683477
US9296736, 132 US9593129, Example 133 US9296736, 133 BDBM215178
2-(3,4-dichloro-5-fluorobenzyl)- 1H-pyrrolo[3,2-b]pyridine-7- carboxylic acid US10174026, Example 132 US9738637, Example 132 BDBM320449
BDBM510272 US11439633, Example 132 US11077100, Example 132 (5R,8R)-N-(2,4- dichlorobenzyl)- 5-fluoro-8- hydroxy-5,6,7,8- tetrahydroquinoline- 5-carboxamide
US10202369, Example 132 BDBM319965 US10174016, Example 132 N-[1-(3-Chloro-5-fluoropyridin-2-yl)ethyl]-3-(5-methyl-1,3-thiazol-2-yl)-5-[(3S)-tetrahydrofuran-3-yloxy]benzamide US10472354, Example 132
US10934296, Example 132 (S)-4-(8-amino-3-(1-but-2- ynoylpyrrolidin-2-yl)imidazo[1,5- a]pyrazin-1-yl)-N-(4-phenylpyridin- 2-yl)benzamide US9758524, Example 132 US10239883, Example 132 BDBM340195
BDBM421542 US10995073, Example 132 US10508086, Example 132 Ethyl 3-[(2,4-dimethylthiazol-5-yl)methyl]-6-[(1-methylcyclopropyl)sulfamoyl]indole-1-carboxylate
US10617680, Example 132 US11020380, Example 132 BDBM437398 5-(1-ethyl-1H-pyrazol-4-yl)-1-methyl-4- phenylpyridin-2(1H)-one
US9790235, Number I-132 BDBM348840 US9790235, Number I-93
BDBM38152 US10093640, Example 132 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-N-((4-phenoxyphenyl)sulfonyl)-1H-indole-2-carboxamide US10844032, Example 132
US12065446, Example 132 US11319329, Ex # 132 US10934310, Ex # 132 BDBM485298 N-((1R,2S)-2-(2-(Dimethylamino)acetamido)cyclohexyl)-5-(*S)-(2- methyl-4-phenoxyphenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide
N-[3-[4-(5-cyanopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-2-[(2S)-1-[6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-4-yl]pyrrolidin-2-yl]acetamide US10870641, Example 132 US11014913, Example 132 BDBM431170 US10550105, Example 132
US10131667, Example 132 1-{[3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-methyl-2-oxo-2,3,4,7-tetrahydro-1H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-8-yl]methyl}piperidine-4-carbonitrile US11053246, Example 132 BDBM301316 US9611267, Example 132
US11130745, Example 132 BDBM470466 US11713304, Example 132 N-(2,6-dichlorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}benzamide US10815215, Example 132
US11608338, Example 132 1-(1,3-Dimethyl-1H-pyrazol- 4-yl)-7-methoxy-3-methyl-8- (2-methyl-3H-benzo- imidazol-5-yl)-1,3-dihydro- imidazo[4,5-c]quinolin-2- one US10457677, Example 132 US10975075, Example 132 BDBM418537
US10202381, Example 132 US10208039, Example 132 BDBM347125 2-(4-((3-(4-isopropylpiperazin-1- yl)phenyl)(methyl)amino)phenoxy) pyrido[3,4-d]pyrimidin-4-ol
US10577367, Example 132 1-(6-(1-(6-methylpyridin-2-yl)-1H-indazol-6-yl)pyridin-2-yl)butan-1-amine BDBM374120 US10246456, Example 132
BDBM361540 US11046689, Example 132 (S)-3-((1R,3R)- 1-(2-(2-((3- fluoropropyl) amino)ethoxy)- 3- methylpyridin- 4-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid US10590132, Example 132 US10221173, Example 132
(R)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-2-morpholinothiazole-4-carboxamide BDBM309986 US11046713, Example 132 US9657003, 132
BDBM379228 US10266549, Example 132 N-(4-((2-((2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acetamide US10774092, Example 132
US10485800, Example 132 US9814704, Example 132 BDBM354855 Preparation of 3-[2-oxo-5-(3,4,5-trimethoxy-phenyl)-1,2-dihydro-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-benzamide
US10544130, Example 132 (R)-2'-amino-3'-cyano-N4- (pyrrolidin-3-yl)-2-(1H-tetrazol- 5-yl)-[1,1'-biphenyl]-3,4- disulfonamide US10221163, Example 132 BDBM360976
US11046712, No 132 US10336775, Example 132 (S)-5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-1,3,4-thiadiazol-2-amine BDBM408228
BDBM513264 N-((1R,2R)-2-hydroxycyclohexyl)-6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-yl)methoxy)pyridine-3-carboxamide US11091471, Example 132 US20240279218, Example 132
US10442772, Example 2-132-2 (�) 4-[(2-{[4-(trifluoromethoxy)phenyl]amino}-1-[(cis)-3,3,5-trimethylcyclohexyl]-1H-benzimidazol-5-yl)oxy]butanoic acid US9957235, 2-132 BDBM390472
US20230357269, Example 132 (13R)-16-fluoro-13-methyl-8,14-dioxa-10,19,20- BDBM634447
5-[[5-[2-methoxy-4-[[[(3S)-tetrahydrofuran-3-yl]amino]methyl]phenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile hydrochloride US10010547, Example 132 BDBM402022 US10973817, Example 132
BDBM267356 3-chloro-5-((1-((2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile US9718819, 132 US10189831, Example 132
BDBM291817 N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-(1,3,5-trimethyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine US9580437, Example 132 US11207325, Example 132
US10246453, Example 132 (S)-2-fluoro-5-methyl-4-(methyl(1-((5-methylfuran-2-yl)methyl)pyrrolidin-3-yl)amino)-N-(thiazol-4-yl)benzenesulfonamide BDBM373865 US10815229, Example 132
US11390618, Example 132 (R)-1-(6-(3-((5-chloropyrimidin-2- yl)amino)pyrrolidine-1-carbonyl)-3,4- dihydroisoquinolin-2(1H)-yl)prop-2- en-1-one BDBM479092 US10894788, Example 132
US11479551, Example 4-132 US11492351, Example 4-132 BDBM579015 2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin-6-yl)-1-methyl-1H- pyrazol-5-yl)-5-chloro-4-methylbenzonitrile
US10570121, Example 132 US10570121, Example 133 US10570121, Example 134 US10570121, Example 135 BDBM435626
US11111242, Example 50 BDBM316523 US20250134869, Example 132 US9617258, Example 11 US9617258, Example 50
WO2022086828, Example 54 WO2018148626, Example 151 WO2022086828, Example 151 WO2022086828, Example 132 BDBM534327
BDBM487339 US10953012, Example 132 3-benzyl-5-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7
4-(5-(3-cyano-6-(1-methyl- 1H-pyrazol-4- yl)pyrazolo[1,5-a]pyridin- 4-yl)pyridin-2-yl)-N,N- dimethylpiperazine-1- carboxamide BDBM284122 US10174027, Example 132 US10023570, Example 132
BDBM425059 N-((S)-5-((1S,2R)-2-(4- fluorophenyl)cyclopropylamino)-1-(4- methylpiperazin-1-yl)-1-oxopentan-2-yl)-4- (1H-1,2,3-triazol-1-yl)benzamide US11230534, Example 132 US10519118, Example 132
N-((3S,4R)-4-Fluoro-1-methylpyrrolidin-3-yl)-5-(2-methyl-4- phenoxyphenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide; US10800792, Example 132 BDBM467480 US10822348, Example 132
US10092575, Example 132 6-(4-Chloro-2-fluorobenzyl)-9-(pyrimidin-2-ylmethyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5 (6H)-one BDBM289644 US10376514, Example 132
{4-[4-({[3- (difluoromethoxy)phenyl]methyl} carbamoyl)-1H-1,2,3-triazol-1-yl] butyl}-N-{[4-(trifluoromethyl) pyridin-2-yl]methyl}-1H-1,2,3- triazole-4-carboxamide US10344025, Example 132 US11370786, Example 132 BDBM404788
BDBM517991 US11111237, Example 132 US11725001, Example 132 4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxy-propyl]-1-methyl-8-(1-methylpyrrolidin- 3-yl)oxy-2,3-dihydro-1,4-benzodiazepin-5-one
(R)-1-(2-(2-(3′-(7-cyano-5-(((R)-3-hydroxypyrrolidin-1-yl)methyl)benzo[d]oxazol-2-yl)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)-4,6-dihydro-5H-pyrrolo[3,4-d]oxazol-5-yl)-2-oxoethyl)pyrrolidine-3-carboxylic acid US10800768, Example 132 US10308644, Example 132 BDBM395520 US11339149, Example 132
2-[4-({[(2- hydroxyphenyl)methyl]amino} methyl)-3,5- dimethoxyphenoxymethyl]-6- phenylbenzonitrile BDBM365880 US9872852, Example 132
3-(5-(1,3,4-oxadiazol-2-yl)pyridin-3-yl)phenyl tetradecylcarbamate BDBM734157 US20250129027, Example 132
3-({[(1R)-6-[(1,3-dihydro-2-benzofuran-5-yl)(methyl)amino]- BDBM293790 US10106534, Example 132
3-{[trans-4-phenyl-1-(propylsulfonyl)pyrrolidin-3-yl]amino}benzonitrile BDBM308624 US9656955, Example 132
BDBM246227 US9434690, 135 US9434690, 134 US9434690, 133 US9822102, Example 135 US9434690, 132 US10183932, Example 135
BDBM396507 US9981909, Example 132 5-[1-[2-(Azetidin-3-yloxy)-4-chloro-phenoxy]-ethyl]-thiazole
BDBM314953 US9611277, Example 132 (6-methyl-3-(2H-1,2,3-triazol-2-yl)pyridin-2-yl)((1S,4R,6R)-6-((5-methylpyrimidin-2-yl)oxy)-2-azabicyclo[2.2.1]heptan-2-yl)methanone US10183953, Example 132
US10239876, Example 132 US10435407, Example 132 BDBM372109 3-[2-[4-Methyl-3-(trifluoromethyl)piperazin-1-yl]-2-oxoethyl]-1-phenyl-8-(1H-pyrazolo[3,4-b]pyridine-5-carbonyl)-1,3,8-triazaspiro[4.5]decan-4-one
US10654853, Example 132 (R)-7′-(5-Methyl-H-indazol-4-yl)-2′-oxo-1′,4′-dihydro-2′H-spiro[pyrrolidine-3,3′-quinoline]-1-carbonitrile US11236092, Example 132 BDBM443359
US10421742, Example 132 BDBM413739 US11180471, Example 132 2-{4-[5-Chloro-2-(4,5-dihydro-1,2-oxazol-3-yl)phenyl]-5-methoxy-2-oxopyridin-1(2H)-yl}-N-(2-methyl-2H-indazol-5-yl)pentanamide (Racemate)
(R)-N-(6-chloropyridin-3-yl)-6- (1-methoxyethyl)isoquinolin- 1-amine BDBM660747 US20240101531, Example 132
2-[3-Bromo-2-(2-oxo-1,3-dihydrobenzimidazol-5-yl)phenyl]acetonitrile; BDBM435959 US10611730, Example 132
BDBM613391 1-[1-(cyanomethyl)-4-(3,3,3- trifluoropropylamino) cyclohexyl]-3- (cyclopropanecarbonylamino) pyrazole-4-carboxamide US11731943, Example 132
BDBM377438 US10676434, Example 131 US11053197, Example 132 5-((S)-3-(But-2-ynamido)piperidin-1-yl)-6-fluoro-2-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (Single Isomer) US10266491, Example 131 US10266491, Example 132
(1-cyclobutylpiperidin-3-yl)(6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)methanoe BDBM383619 US10280149, Example 132
(S,E)-1-(2-(Hydroxymethyl)-4-((2-methyloxazol-4-yl)methyl)piperazin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one BDBM322036 US9763957, Example 132 US10183025, Example 132
(S)-quinuclidin-3-yl (6-(3-isopropoxyphenyl)-2,2-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)carbamate US12338237, Example 132 BDBM753374
3-(4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-N-(3,3- difluorocyclobutyl)-4-methylbenzenesulfonamide BDBM421096 US10479795, Example 132
US9475819, 132 BDBM164001 US9637496, 132 US9062078, 132 US9695183, 132
US9089569, 132 US9695149, 132 US8952177, 132 BDBM145778
US10646492, Example 132 US10092570, Example 132 BDBM261109 US11433071, Example 132 US10376513, Example 132 US9730939, Example 132 US9707233, 132
US10913746, Compound 132 US9777010, Compound 132 US11649240, Compound 132 US10407433, Compound 132 US10072016, Compound 132 US9434727, 132 BDBM249534
BDBM202785 US10245267, Example 132 US9242969, 132 US9694016, 132 US10709712, Example 132
BDBM161347 US10087143, Compound 132 US10738009, Compound 132 US9051270, 132 US11673864, Compound 132 US9758483, Compound 132
US11667644, Example 132 USRE48841, Example 132 US9586962, Example 132 US8653263, 132 BDBM118479 US11059828, Example 132
US9688629, 132 US10604504, Example 132 US11623921, Example 132 US9920031, Example 132 BDBM165348 US9802915, Example 132
US11021515, Compound 132 US10640534, Compound 132 BDBM363645 US9850277, Compound 132 US10717764, Compound 132 US11667673, Compound 132 US10689414, Compound 132
BDBM150458 US10238633, Example 132 US9713606, 132 US8987249, 132
US10077266, Example 132 BDBM191020 US9708313, 132 US9181249, 132
US10640503, Example 132 US9695168, 132 US10047086, 132 BDBM105784
BDBM127759 US9782415, Example 132 US8791123, 132 US9796724, Example 132 US10758542, Example 132
US10213433, Compound 132 US9174982, 132 US20240043404, Example 132 US11369599, Compound 132 BDBM189570
US10703749, Example 132 US10112937, Example 132 US9464084, 132 US10150765, Example 132 BDBM254246
US9434697, 132 US10537571, Compound 132 BDBM249415 US10912774, Compound 132 US9730931, Compound 132
US10137124, Example 132 US10112942, Example 132 BDBM296398 US10555944, Example 132 US10953005, Example 132 US10172851, Example 132
US10881652, Example 132 BDBM305116 US10172845, Example 132 US10441581, Example 132 US10144734, Example 132 US11648243, Example 132
US11548872, Compound 132 BDBM293510 US10106527, Compound 132 US10544128, Compound 132 US9951048, Compound 132 US20230286945, Compound 132
US20230271960, Compound 132 US20230293519, Compound 132 US11560376, Compound 132 US10793564, Compound 132 US11419869, Compound 132 BDBM465342
BDBM397069 US11591338, Example 132 US10844069, Example 132 US10442810, Example 132 US9981975, Example 132
BDBM513771 US11220509, Example 132 US11091495, Example 132 US20240398811, Example 132 US11485738, Example 132
US10307413, Compound 132 US10980794, Cmpd No 132 BDBM177670 US10391089, Compound 132 US9675614, 132
US11111235, No. 132 US11591316, Compound 132 US10590114, No. 132 BDBM384446 US9932325, Example 132
BDBM172126 US11052093, Compound 132 US10155002, Compound 132 US9090562, 132
BDBM173423 US9096596, 132 US10323032, Example 132 US9604982, Example 132
BDBM185313 US10011588, Example 132 US9156829, 132 US10689373, Example 132
US10544133, Example 132 US9657009, 132 BDBM283940 US10023562, Example 132
US11046688, Example 132 BDBM241290 US10479788, Example 132 US9409907, 132
US8865911, 132 US9918985, Example 132 US10231967, Example 132 BDBM136910
US9321760, 132 US9662330, Compound 132 BDBM224455 US10080750, Compound 132
US9447106, 132 US10005782, Compound 132 BDBM250006 US9556188, Compound 132
US9452980, 132 US10501411, Example 132 US11697636, Example 132 BDBM250222
US9745328, Compound 132 US9884878, Compound 132 BDBM168742 US9079866, 132
BDBM110664 US8614234, 132 US9725433, 132
BDBM160422 US9040714, 132 US9693992, 132
BDBM165097 US9682971, 132 US9067917, 132
BDBM192473 US9687476, 132 US9187466, 132
BDBM197532 US9216968, 132 US9732066, 132
BDBM221636 US9303045, 132 US9695195, 132
BDBM70977 US9546164, 132 US9694002, 132
US10047103, 132 US9688695, 132 BDBM176099
US8952157, 132 US9303025, 132 BDBM144950
US9206232, 132 US8613914, 132 BDBM110364
BDBM343533 US10442803, Example 132 US9777003, Example 132 US11091484, Example 132
BDBM356392 US10604535, Example 132 US9815850, Compound 132 US9896458, No. 132
BDBM469113 US11608330, Example 132 US10807974, Example 132 US10995088, Example 132
US10632171, Peptide No. 132 US9458201, 132 BDBM253653 US10179804, Example 132
US10730877, Example 132 BDBM427699 US10544143, Example 132 US11053244, Example 132
US10793579, Example 132 US11702424, Example 132 US10329302, Example 132 BDBM402985
US10800783, Example 132 US11396512, Example 132 US10233188, Example 132 BDBM370245
US10807986, Example 132 BDBM311680 Ex. Cpd. 132 US11046696, Compound 132
US10988451, Example 132 US10703733, Example 132 BDBM449519 US11643400, Example 132
US12180213, Example 132 BDBM458658 US10745401, Example 132 US11466007, Example 132
US20240101536, Example 132 US12240835, Example 132 US10889571, Example 132 BDBM477787
US9745310, Example 132 BDBM292277 US10100057, Example 132 US11046702, Example 132
BDBM162513 US9611222, Example 132 US9056832, 132
BDBM171498 US9085576, 132 US9611261, Example 132
BDBM241500 US9409908, 132 US9951071, Example 132
BDBM244907 US9738649, Example 132 US9422293, 132
BDBM259891 US10308662, Compound 132 US9505780, 132
US11547697, Compound 132 BDBM125252 US9682141, 132
US8853203, 132 US9650377, Example 132 BDBM136118
US9073922, 132 BDBM167645 US9796708, Example 132
US9200016, 132 US9902710, Compound 132 BDBM194450
US9216999, 132 US9556187, Example 132 BDBM198325
US9540323, 132 BDBM260940 US9540323, example 132
US9604984, Example 132 US9346815, 132 BDBM232586
US9682966, 132 BDBM155908 US10118915, Compound 132
US9845313, Example 132 BDBM258225 US9493448, 132
US10202383, Example 2(132) US9556175, 2(132) US9321791, 2(132) BDBM224594
US10618902, Compound I-132 US10189794, Compound I-132 US10774052, Compound I-132 BDBM101174 US9695132, I-132
US9987276, Compound I-132 US10828300, Compound I-132 BDBM397327 US10596172, Compound I-132 US11351168, Compound I-132
BDBM137064 US8871790, 132 US20250017938, Compound 001-132
BDBM271317 US10975091, Example 132 US10059720, Example 132
BDBM273351 US10478424, Example 132 US10071079, Example 132
BDBM316641 US11111242, Example 132 US9617258, Example 132
BDBM393844 US10597367, Example 132 US9969726, Example 132
BDBM406186 US10889589, EX. # 132 US10351575, Example 132
BDBM414715 US10435405, Example 132 US10934288, Example 132
BDBM434210 US10562891, Example 132 US11008308, Example 132
BDBM438971 US11180455, Compound 132 US10604489, Compound 132
BDBM448900 US10696672, Compound 132 US11634418, Compound 132
BDBM459623 US10772893, Example 132 US11529356, Example 132
BDBM484720 US11713320, Compound 132 US10934297, Compound 132
BDBM50349734 US9771375, Example 132 US8822447, 132 CHEMBL1809161
BDBM578284 US11478474, Compound 132 US12070457, Compound 132
BDBM625107 US20230322747, Compound 132 US20250250263, Compound 132
BDBM99421 US8497281, 199 US9663470, 132 US9120769, 132
US10072001, Example 132 BDBM276956 US10259811, Example 132
US10166214, Example 132 US10675268, Example 132 BDBM311996
US10172864, Compound 132 US10028961, Compound 132 BDBM279979
US10214492, Example 132 BDBM356768 US11292767, Example 132
US10273259, Example 132 US10711020, Example 132 BDBM382420
US10301317, Example 132 US9624228, Example 132 BDBM318176
US10562916, Compound 132 BDBM362572 US9834564, Compound 132
US10597366, Compound 132 US9896418, Compound 132 BDBM373001
US10723742, Example 132 BDBM456411 US11510915, Example 132
US10774053, Compound 132 US11352329, COMPD # 132 BDBM461010
US10781211, Example 132 US10030020, Example 132 BDBM280587
US10807991, Compound 132 BDBM321314 US10179791, Compound 132
US10875852, Example 132 BDBM303620 US10138229, Example 132
US11117861, Example 132 BDBM450369 US10676431, Example 132
US11453683, Example 132 BDBM573304 US20230279025, Example 132
US11555029, No. 132 BDBM451992 US10710986, Example 132
US11718603, Example 132 BDBM498307 US11014911, Example 132
US8604016, 132 US9938267, Cmpd ID 132 BDBM108566
US9765068, Compound 132 US9745291, Compound 132 BDBM337086
US9790229, Compound 132 US10577374, Compound 132 BDBM348409
BDBM423677 US11046698, Compound I-132 US10508120, Compound I-132 US10577373, Compound I-132
US10323036, Compound I-132 US10793574, Compound I-132 US11220508, Compound I-132 BDBM399688
BDBM444596 US10988476, Compound I-132 US10662186, Compound 132
BDBM50389728 US10544104, Compound 132 US9765037, Compound 132 CHEMBL2069944
US10017501, Compound 1020-132 BDBM249300 US9458145, 1020-132
US11040034, Ex. No. 132 BDBM287754 US10085984, Example 132
US20250017938, Compound 002-132 BDBM367315 US10226449, cpd 132
US9663506, Example 4-132 US9278960, 4-132 BDBM213048
BDBM337956 US9751854, Compound I-132 US9802960, Compound I-132
BDBM405681 US10597377, Compound 2-132 US10351547, Compound 2-132
BDBM420463 US10961232, Compound I-132 US10479784, Compound I-132
BDBM439824 US10633389, Example 132-1a US20230279020, Example 132-1a
BDBM455111 US10730874, Compound I-132 US11352356, Compound I-132
BDBM565566 US12221453, Compound I-132 US11414431, Compound I-132
US10479784, Compound IA-132 BDBM420628 US10961232, Compound IA-132
US10533010, Example I-132 US11208415, Example I-132 BDBM429035
US11396508, Compound I-132 US10647713, Compound I-132 BDBM442170
US11434240, Compound I-132 US10781204, Compound I-132 BDBM463653
US20230279020, Example 132-3 BDBM440467 US10633389, Example 132-3
US9732060, Compound I-132 US10065941, Compound I-132 BDBM271631
US9732060, Compound R-132 BDBM271817 US10065941, Compound R-132
US9957235, 2-132-1 US9957235, 2-132-2 BDBM390473
US11535614, Compound 132 US9624217, Compound 131 US9624217, Compound 130 US10807980, Compound 132 US9624217, Compound 132 BDBM317972 US9624217, Compound 125 US10399976, Compound 132
US9611252, Example 132 N-((1-aminoisoquinolin-6-yl)methyl)-2-((3- methylisoquinolin-6-yl)methyl)isonicotinamide BDBM283480 US11021463, Example 132 US10266515, Example 132 US10023557, Example 132 US10308637, Example 132
US10392391, Compound I-N-132 US11117900, Compound I-N-132 US10787452, Compound I-N-132 BDBM411700
US10723734, Example 132 BDBM311276 US9902722, Example 132 US10351563, Example 132 (S)-1-((4-(difluoromethyl)-6-(6-fluoroquinolin-4-yl)pyridin-3-yl)oxy)-2,4-dimethylpentan-2-amine US10155760, Example 132 US10981910, Example 132 US10544120, Example 132
BDBM101159 US8524917, 132
BDBM101635 US8530652, 132
BDBM103155 US8541407, 132
BDBM103707 US8563553, 132
BDBM104712 US8569308, 132
BDBM109411 US8604061, 132
BDBM111137 US9695179, 132
BDBM115314 US8637500, 132
BDBM118704 US9682940, 132
BDBM119575 US8680275, 132
BDBM121693 US8722692, 132
BDBM123619 US8748624, 132
BDBM125737 US8772305, 132
BDBM126108 US8779142, 132
BDBM126648 US8785638, 132
BDBM128550 US8796244, 132
BDBM128962 US8802711, 132
BDBM129490 US8802673, 132
BDBM130275 US8815840, 132
BDBM131722 US8835470, 132
BDBM134130 US8846689, 132
BDBM134234 US8846673, 132
BDBM134669 US8846698, 132
BDBM136501 US8865726, 132
BDBM140072 US8901315, 132
BDBM140701 US8912224, 132
BDBM141238 US8653100, 132
BDBM142539 US8933224, 132
BDBM143931 US8969325, 132
BDBM144381 US8969358, 132
BDBM145353 US8952169, 132
BDBM146097 US8957068, 132
BDBM147301 US8957093, 132
BDBM150943 US8981106, 132
BDBM151697 US8987445, 132
BDBM151938 US8987457, 132
BDBM152046 US8987473, 132
BDBM152397 US8993565, 132
BDBM153615 US8999975, 132
BDBM155700 US9012651, 132
BDBM157293 US9023865, 132
BDBM158424 US9029393, 132
BDBM159990 US9040528, 132
BDBM161673 US9682976, 132
BDBM163505 US9062048, 132
BDBM164321 US9688615, 132
BDBM167046 US9073876, 132
BDBM169599 US9079880, 132
BDBM169783 US9073940, 132
BDBM170413 US9079929, 132
BDBM173030 US9096579, 132
BDBM175583 US9688680, 132
BDBM178573 US9125913, 132
BDBM180247 US9133157, 132
BDBM181929 US9145380, 132
BDBM182431 US9145392, 132
BDBM183512 US9145354, 132
BDBM184262 US9150577, 132
BDBM185479 US9156845, 132
BDBM186469 US9163021, 132
BDBM187559 US9169252, 132
BDBM188866 US9169260, 132
BDBM189912 US9174997, 132
BDBM189979 US9175003, 132
BDBM193212 US9193736, 132
BDBM194216 US9200001, 132
BDBM196027 US9206199, 132
BDBM197865 US9216988, 132
BDBM199067 US9221832, 132
BDBM201701 US9233979, 132
BDBM203575 US9221809, 132
BDBM204013 US9242996, 132
BDBM205663 US9255090, 132
BDBM206219 US9255110, 132
BDBM206393 US9260425, 132
BDBM206812 US9249163, 132
BDBM208434 US9266835, 132
BDBM214070 US9283222, 132
BDBM214933 US9296734, 132
BDBM220543 US9296741, 132
BDBM221017 US9302996, 132
BDBM221206 US9303012, 132
BDBM223910 US9328112, 132
BDBM229390 US9556135, 132
BDBM229805 US9334269, 132
BDBM231746 US9340517, 132
BDBM233525 US9351965, 132
BDBM236965 US9388189, 132
BDBM238502 US9394297, 132
BDBM239945 US9403767, 132
BDBM241037 US9409892, 132
BDBM244523 US9428502, 132
BDBM245677 US9428508, 132
BDBM247903 US9434719, 132
BDBM249704 US9447038, 132
BDBM250828 US9452986, 132
BDBM252551 US9458172, 132
BDBM253172 US9458171, 132
BDBM255173 US9475817, 132
BDBM255381 US9481682, 132
BDBM257114 US9493435, 132
BDBM257288 US9493440, 132
BDBM259619 US9505749, 132
BDBM264410 US9714247, 132
BDBM302220 US9598415, 132
BDBM302991 US9598440, 132
BDBM327591 US9663469, 132
BDBM389813 US9951063, 132
BDBM5275 US8530490, 132
BDBM77464 US9695118, 132
BDBM99631 US8501936, 132
US10047096, 132 BDBM227871
US8481733, 132 BDBM98320
US8486940, 132 BDBM64757
US8487093, 132 BDBM98764
US8501750, 132 BDBM99962
US8507533, 132 BDBM100825
US8530648, 132 BDBM102261
US8569281, 132 BDBM105115
US8575145, 132 BDBM104255
US8575186, 132 BDBM104369
US8575201, 132 BDBM104641
US8592455, 132 BDBM106932
US8614223, 132 BDBM139346
US8623889, 132 BDBM112134
US8633206, 132 BDBM113213
US8637532, 132 BDBM116451
US8648092, 132 BDBM117201
US8674113, 132 BDBM118875
US8697911, 132 BDBM119967
US8703768, 132 BDBM120532
US8772323, 132 BDBM180633
US8772480, 132 BDBM125314
US8778951, 132 BDBM126322
US8791131, 132 BDBM127374
US8802864, 132 BDBM128366
US8815926, 132 BDBM129853
US8822458, 132 BDBM130535
US8841312, 132 BDBM132386
US8841455, 132 BDBM132037
US8846601, 132 BDBM135747
US8846658, 132 BDBM134415
US8846699, 132 BDBM133814
US8846719, 132 BDBM133445
US8846746, 132 BDBM132862
US8853258, 132 BDBM135504
US8871934, 132 BDBM137539
US8912181, 132 BDBM140506
US8921389, 132 BDBM141675
US8940736, 132 BDBM142789
US8957074, 132 BDBM147092
US8962637, 132 BDBM148406
US8969341, 132 BDBM143519
US8975417, 132 BDBM150072
US9012443, 132 BDBM154124
US9012443, 132 BDBM154126
US9018214, 132 BDBM156081
US9029370, 132 BDBM158338
US9034866, 132 BDBM158657
US9056843, 132 BDBM162841
US9067871, 132 BDBM164654
US9067922, 132 BDBM165797
US9067949, 132 BDBM166275
US9073853, 132 BDBM166573
US9073870, 132 BDBM166836
US9073881, 132 BDBM167380
US9085555, 132 BDBM170704
US9120812, 132 BDBM178347
US9150526, 132 BDBM183879
US9150566, 132 BDBM184094
US9169224, 132 BDBM188443
US9187424, 132 BDBM201367
US9199947, 132 BDBM193633
US9216972, 132 BDBM197672
US9233953, 132 BDBM201169
US9234000, 132 BDBM200141
US9242970, 132 BDBM202984
US9260439, 132 BDBM207155
US9265773, 132 BDBM208187
US9266876, 132 BDBM208665
US9266877, 132 BDBM209186
US9273033, 132 BDBM209830
US9278981, 132 BDBM213540
US9290451, 132 BDBM210384
US9290485, 132 BDBM212100
US9296745, 132 BDBM215576
US9302989, 132 BDBM217007
US9303023, 132 BDBM221435
US9315498, 132 BDBM222843
US9321756, 132 BDBM224877
US9328106, 132 BDBM227184
US9346798, 132 BDBM231385
US9353090, 132 BDBM234004
US9353104, 132 BDBM234827
US9365576, 132 BDBM236379
US9394285, 132 BDBM238045
US9394309, 132 BDBM239675
US9394331, 132 BDBM240870
US9403813, 132 BDBM240226
US9428504, 132 BDBM245382
US9434725, 132 BDBM248901
US9458110, 132 BDBM252061
US9458176, 132 BDBM252735
US9464044, 132 BDBM250495
US9481672, 132 BDBM255954
US9493446, 132 BDBM257662
US9499482, 132 BDBM258733
US9505762, 132 BDBM259764
US9675593, 132 BDBM168578
US9682955, 132 BDBM143501
US9693997, 132 BDBM70482
US9695170 132 BDBM109214
US9708253, 132 BDBM261473
US9708359, 132 BDBM263168
USRE46792, 132 BDBM389058
BDBM383849 US10550099, Compound I-132 US10280150, Cmpd No I-132
US10577336, Example 132 US10071974, Example 131 US10071974, Example 132 BDBM276020
US11459335, Compound 132 US11459335, Compound 159 US20230279023, Compound 132 BDBM575333
US11718626, Compound T-132 US11053253, Cmp No. T-132 BDBM516722
US9999619, Example 133 US11285140, Example 132 US10695337, Example 132 BDBM400378
2-(2-(2-hydroxypropan- US10189841, Compound I-132 US11161848, Compound I-132 BDBM324926 US10399980, Compound I-132
2-[5-[(2,4- dimethylphenyl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid US9604961, Example 132 US9908865, Example 132 US10173996, Example 132 US9714230, 132 BDBM264047
BDBM559762 US20230271963, Compound I-N-132 US11370798, Cmpd. # I-N-132
BDBM105622 US8575197, I-132
BDBM106219 US8575197, II-132
BDBM115987 US8633183, E-132
BDBM122662 US8735386, I-132
BDBM131901 US8835436, Example 132
BDBM227638 MTH1 inhibitor, 132
BDBM258291 US9493485, 9-132
BDBM268730 US9718825, Example 132
BDBM270411 US10059667, Example 132
BDBM272290 US10065950, Example 132
BDBM282637 US9884828, 2-132
BDBM288823 US10092551, Example 132
BDBM288994 US10092563, Compound 132
BDBM290551 US10099993, Compound 132
BDBM314018 US10167299, Example 132
BDBM317359 US9617282, Example 132
BDBM317979 US9624217, Compound 132
BDBM326435 US9662327, Compound 132
BDBM330951 US9725445, 3-132
BDBM331711 US9725465, Example 132
BDBM337510 US9745321, Compound 132
BDBM339687 US10202339, Compound 132
BDBM340603 US9763922, Example 132
BDBM341898 US9771320, Example 132
BDBM347926 US9790221, Compound 132
BDBM348213 US9790228, Compound 132
BDBM350822 US10208081, Example 132
BDBM355041 US9815796, Example 132
BDBM357176 US10214512, Example 132
BDBM357406 US10214519, Example 132
BDBM358817 US10214544, Example 132
BDBM362343 US9834548, Example 132
BDBM368717 US10227350, Compound 132
BDBM369625 US10233152, Example 132
BDBM380517 US9926318, 1-132
BDBM381775 US10272079, Compound 132
BDBM387984 US10294229, Example 132
BDBM390245 US9951086, Example 132
BDBM390868 US9957263, Example 132
BDBM392934 US10301306, Example 132
BDBM397921 US9994552, Compound 132
BDBM403857 US10336717, Compound 132
BDBM405957 US10351558, Example 132
BDBM410372 US10377770, Example 132
BDBM410919 US10383880, Example 132
BDBM413948 US10421756, Compound 132
BDBM419794 US10464919, Example 132
BDBM429312 jm5b01461, Compound 132
BDBM437698 US10617706, Example 132
BDBM438311 US10618897, Example 132
BDBM438504 US10618903, Example 132
BDBM445811 US10669240, Compound 132
BDBM450015 US10703755, Example 132
BDBM451305 US10709709, Example 132
BDBM451534 US10710967, Example 132
BDBM453078 US10711036, Compound 132
BDBM454963 US10730870, Example 132
BDBM458037 US10752596, Example 132
BDBM458234 US10752615, Compound 132
BDBM462520 US10766903, Example 132
BDBM468720 US10807959, Example 132
BDBM475082 US10849901, Compound 132
BDBM479173 US10894789, Compound 132
BDBM480918 US10906888, Example 132
BDBM486326 US10946023, Compound 132
BDBM487576 US10954193, Example 132
BDBM489878 US10966980, Example 132
BDBM493431 US10981917, Example 132
BDBM500120 US11021457, Compound 132
BDBM500273 US11021467, Compound 132
BDBM509025 US11071730, Example 132
BDBM509388 US11072611, Compound 132
BDBM510678 US11078186, Example 132
BDBM514904 US11098041, Example 132
BDBM515265 US11098058, Example 132
BDBM516042 US11053226, Example 132
BDBM528262 US11180494, Example 132
BDBM530841 WO2022076496, Example 132
BDBM536539 US11242361, Compound 132
BDBM537152 US11247989, Example 132
BDBM538791 US11254668, Example 132
BDBM541925 US11267824, Example 132
BDBM544648 US11286268, Compound 132
BDBM554106 US11325916, Example 132
BDBM555456 US11344549, Example 132
BDBM556249 US11345699, Example 132
BDBM561303 US11390610, Example 132
BDBM565082 US11414395, Example 132
BDBM580787 US11492346, Example 132
BDBM582069 US11518761, Example 132
BDBM583006 US11548892, Compound 132
BDBM584384 US11524968, Example 132
BDBM585257 US11530197, Compound 132
BDBM586159 US11530244, Compound 132
BDBM587422 US11534441, Compound 132
BDBM587882 US11535621, Example 132
BDBM589161 US11548900, Example 132
BDBM589204 US11548903, Example 132
BDBM592458 US11572368, Compound 132
BDBM594153 US11583538, Example 132
BDBM594337 US11584747, Example 132
BDBM594843 US11584755, Example 132
BDBM595825 US11591336, Compound 132
BDBM596779 US11596639, Example 132
BDBM601737 US11642348, Compound 132
BDBM603159 US11649255, Example 132
BDBM607208 US11685745, Example 132
BDBM614119 US11744824, Example 132
BDBM615026 US20230271941, Compound 132
BDBM615341 US20230271949, Example 132
BDBM616626 US20230278996, Example 132.
BDBM620272 US20230295171, Example 132
BDBM621380 US11773078, Example 132
BDBM622172 US20230312550, Example 132
BDBM622455 US20230312576, Compound 132
BDBM623115 US11780845, Example 132
BDBM626484 US11787780, Example 132
BDBM629016 US20230339891, Example 132
BDBM631862 US20230348426, Example 132
BDBM634683 US11814367, Compound 132
BDBM638029 US11834453, Example 132
BDBM638537 US11834467, Example 132
BDBM641057 US20230399342, Example 132
BDBM641238 US11845723, Example 132
BDBM642506 US11851426, Example 132
BDBM646491 US11878973, Example 132
BDBM648164 US20240025922, Example 132
BDBM648740 US20240034729, Compound 132
BDBM649443 US20240034743, Compound 132
BDBM657315 US11926628, Example 132
BDBM658299 US20240083900, Example 132
BDBM658636 US20240083908, Example 132
BDBM659015 US20240092758, Example 132
BDBM659519 US20240092770, Compound 132
BDBM665448 US20240116910, Compound 132
BDBM666099 US20240116946, Example 132
BDBM668836 US11964953, Example 132
BDBM669149 US11964973, Example 132
BDBM670188 US11970474, Example 132
BDBM675373 US20240158414, Example 132
BDBM676664 US20240166643, Example 132
BDBM681573 US20240199605, Example 132
BDBM681845 US20240199649, Compound 132
BDBM684072 US20240218021, Example 132
BDBM686687 US20240246937, Example 132
BDBM695411 US12083101, Example 132
BDBM696136 US20240300936, Example 132
BDBM699697 US12110299, Example 132
BDBM700031 US20240335442, Compound 132
BDBM702170 US20240360134, Example 132
BDBM702389 US20240360148, Example 132
BDBM702778 US20240360157, Example 132
BDBM703186 US20240368104, Example 132
BDBM705315 US20240376126, Example 132
BDBM706611 US20240383915, Example 132
BDBM712872 US20250019374, Compound 132
BDBM713896 US12202835, Example 132
BDBM714968 US20250026748, Compound 132
BDBM715647 US20250026766, Example 132
BDBM716694 US20250034135, Compound 132
BDBM717557 US20250034165, Example 132
BDBM718277 US20250042889, Example 132
BDBM723019 US20250059220, Compound 132
BDBM723558 US20250064789, Compound 132
BDBM725925 US20250074911, Example 132
BDBM730410 US20250120927, Compound 132
BDBM730550 US20250122174, Example 132
BDBM730919 US20250122183, Example 132
BDBM732326 US20250115561, Example 132
BDBM732417 US20250115563, Compound 132
BDBM733002 US20250115583, Example 132
BDBM734589 US20250129067, Compound 132
BDBM735114 US20250129078, Compound 132
BDBM735545 US20250129103, Compound 132
BDBM737403 US20250136596, Example 132
BDBM738925 US20250145633, Example 132
BDBM740828 US12303509, Example 132
BDBM741010 US12304897, Compound 132
BDBM744047 US20250170104, Compound 132
BDBM744211 US20250170122, Compound 132
BDBM745652 US12319655, Example 132
BDBM746962 US20250179047, Example 132
BDBM747904 US12325701, Example 132.
BDBM749079 US20250188079, Compound 132
BDBM749511 US12331033, Example 132
BDBM750480 US20250195475, Example 132
BDBM751866 US20250197382, Compound 132
BDBM753010 US20250197428, Example 132
BDBM753140 US12338220, Example 132
BDBM753722 US20250206717, Example 132
BDBM755499 US20250214932, Example 132
BDBM756884 US20250221979, Example 132
BDBM757494 US12357603, Example 132
BDBM757704 US12358907, Example 132
BDBM764798 US20250257059, Example 132
US10005792, Compound 132 BDBM401773
US10022354, Example 132 BDBM281192
US10035760, Example 132 BDBM279307
US10059705, II-132 BDBM270737
US10059713, Example 132 BDBM271014
US10071974, Example 132 BDBM276021
US10112899, Example 132 BDBM294653
US10125118, Example 132 BDBM298726
US10131675, Example 132 BDBM301645
US10189816, Compound 132 BDBM324139
US10189859, Compound 132 BDBM331906
US10221177, Compound 132 BDBM361769
US10227329, Compound 132 BDBM367720
US10227338, Example 132 BDBM368345
US10239870, Example 132 BDBM371908
US10308660, Example 132 BDBM396030
US10358446, Compound 132 BDBM408604
US10435369, Example 132 BDBM414245
US10450301, Example 132 BDBM419053
US10457654, Example 132 BDBM417271
US10457703, Example 132 BDBM419470
US10508105, Compound 132 BDBM422783
US10544132, Example 132 BDBM427191
US10562902, Compound 132 BDBM434726
US10626095, Example 132 BDBM610825
US10653688, Compound 132 BDBM442956
US10660877, Example 132 BDBM443549
US10730863, Example 132 BDBM453804
US10844044, Example 132 BDBM473353
US10894782, No 132 BDBM478277
US10899735, No. 132 BDBM479673
US10934302, Example 132 BDBM484881
US10947215, Example 132 BDBM486493
US11008314, Compound 132 BDBM498048
US11014963, Example 132 BDBM499233
US11021493, Example 132 BDBM501213
US11045457, Example 132 BDBM506532
US11053213, Example 132 BDBM514390
US11053225, Compound 132 BDBM515831
US11136311, Compound 132 BDBM523642
US11142525, Example 132 BDBM519731
US11186582, Example 132 BDBM527203
US11203591, Example 132 BDBM529724
US11225469, Compound 132 BDBM533817
US11242337, Example 132 BDBM536029
US11261186, Example 132 BDBM540206
US11267811, Example 132 BDBM541536
US11292791, Example 132 BDBM546859
US11299480, Example 132 BDBM549119
US11312722, Compound 132 BDBM551842
US11365191, Example 132 BDBM558052
US11377439, Example 132 BDBM560295
US11420970, Example 132 BDBM567931
US11420973, Example 132 BDBM568254
US11427563, Compound 132 BDBM569260
US11433053, Example 132 BDBM570244
US11458138, Example 132 BDBM574303
US11530193, Example 132 BDBM585217
US11559538, Example 132 BDBM589880
US11660293, Example 132 BDBM604028
US11667652, Example 132 BDBM605338
US11680060, Example 132 BDBM606058
US11691968, Example 132 BDBM608103
US11697648, Example 132 BDBM608563
US11725000, Compound 132 BDBM612870
US11866430, Example 132 BDBM644209
US11912668, Example 132 BDBM653852
US11912682, Compound 132 BDBM654033
US11912686, Compound 132 BDBM654187
US11926614, Example 132 BDBM657102
US12128028, Example 132 BDBM701736
US12173018, Example 132 BDBM708204
US12194050, Example 132 BDBM712622
US12384753, Example 132 BDBM763109
US12391697, Example 132 BDBM765503
US20230278998, Compound 132 BDBM616814
US20230286943, Example 132 BDBM617664
US20230286970, Compound 132 BDBM618298
US20230322846, Example 132 BDBM625728
US20230339890, Compound 132 BDBM628783
US20230339981, Example 132 BDBM629444
US20230348450, Example 132 BDBM632750
US20230348456, Compound 132 BDBM633111
US20230357253, Compound 132 BDBM634240
US20230364079, Example 132 BDBM635719
US20230365546, Compound 132 BDBM636349
US20230382904, Compound 132 BDBM637212
US20240025884, Example 132 BDBM646921
US20240025919, Compound 132 BDBM647900
US20240043427, Example 132 BDBM650046
US20240067631, Compound 132 BDBM655971
US20240091200, Example 132 BDBM658841
US20240101572, Example 132 BDBM661523
US20240116877, Example 132 BDBM664863
US20240116922, Example 132 BDBM665830
US20240132480, Example 132 BDBM669731
US20240140931, Compound 132 BDBM670541
US20240158369, Compound 132 BDBM674868
US20240174662, Example 132 BDBM677468
US20240245673, Example 132 BDBM686020
US20240246964, Compound 132 BDBM687131
US20240247015, Example 132 BDBM688020
US20240287022, Example 132 BDBM693684
US20240287079, Example 132 BDBM693962
US20240294551, Example 132 BDBM694966
US20240316047, Example 132 BDBM697349
US20240383893, Compound 132 BDBM706260
US20240409609, Compound 132 BDBM707591
US20250059174, Example 132 BDBM721869
US20250084074, Example 132 BDBM726818
US20250092039, Compound 132 BDBM728307
US20250115591, Example 132 BDBM733272
US20250115600, Compound 132 BDBM733626
US20250127903, Compound 132 BDBM733836
US20250145606, Example 132 BDBM738573
US20250145642, Compound 132 BDBM739637
US20250154115, Compound 132 BDBM739922
US20250171452, Compound 132 BDBM745460
US20250179055, Compound 132 BDBM747111
US20250197368, Example 132 BDBM751620
US20250197406, Example 132 BDBM752541
US20250214991, Compound 132 BDBM755999
US20250230159, Example 132 BDBM758487
US20250243180, Compound 132 BDBM761141
US8501732, I-132 BDBM100572
US8633183, D-132 BDBM115753
US8653087, III-132 BDBM117452
US8815934, No. 132 BDBM129648
US8829199, 132 BDBM50197685 BDBM130866
US8975265, 2-132 BDBM149630
US9056865, A-132 BDBM163005
US9115140, I-132 BDBM175254
US9150519, 1-132 BDBM183729
US9150578, I-132 BDBM184503
US9212130, I-132 BDBM196229
US9247759, 5-132 BDBM211185
US9359338, Exe. 132 BDBM235522
US9433622, DMX- 132 BDBM246058
US9546153, ex. 132 BDBM209440
US9573958, Compound 132 BDBM290239
US9745283, Example 132 BDBM336703
US9758538, Example 132 BDBM340443
US9777008, Compound 132 BDBM343838
US9815846, Compound 132 BDBM356132
US9862730, Example 132 BDBM364673
US9873693, Compound 132 BDBM366209
US9926281, Compound 132 BDBM379743
US9938222, Example 132 BDBM387003
US9951027, 3-132 BDBM389498
WO2022064009, Compound 132 BDBM530354
WO2022081807, Example 132 BDBM534025
BDBM190177 EPZ004710 US10273223, Compound B-132 US9637472, Compound B-132 US9175331, 2
BDBM404480 US11066365, Example 132 US11390584, Example 132 US10343992, Example 132 US10689345, Example 132 (R)-N-(1-cyanopyrrolidin- 3-yl)-5-(1-ethyl-1H- pyrazol-4-yl)-4- methylpicolinamide
US10730870, Example 129 BDBM454960 US10730870, Example 128 US10730870, Example 132 US11512083, Example 132
BDBM244380 US9550763, Compound I-132
BDBM323395 US9630956, Compound I-132
BDBM332843 US10196390, Compound I-132
BDBM375913 US9914731, Ex. No. 132
BDBM388435 US10294246, Compound No. 132
BDBM398403 US10323018, Compound I-132
BDBM464803 US10793563, Compound I-132
BDBM482065 US10913753, Compound I-132
BDBM482984 US10919885, Compound No. 132
BDBM50547892 CHEMBL4788313 US11377438, Example 132
BDBM50548952 CHEMBL4795057 US20230365568, Compound 132
BDBM50607683 US20240239774, Example 132 CHEMBL5219579
BDBM532878 US11214565, Example D-132
BDBM548736 WO2022098806, Compound 1-132
BDBM566763 US11420958, Ex. No. 132
BDBM581811 US11512080, Compound I-132
BDBM582123 US11518764, Compound I-132
BDBM607972 US11691963, Example I-132
BDBM617185 US11753403, Compound I-132
BDBM638930 US20230390274, Compound A-132
BDBM673913 US20240150321, Compound I-132
BDBM678296 US20240174690, Example II-132
BDBM682703 US20240208944, Compound TG15-132
BDBM715513 US20250026765, Compound I-132
BDBM721394 US12227509, Example I-132
BDBM722060 US20250059174, Example 132-2
BDBM722061 US20250059174, Example 132-3
BDBM722064 US20250059174, Example 132-6
BDBM722065 US20250059174, Example 132-7
BDBM722068 US20250059174, Example 132-10
BDBM722069 US20250059174, Example 132-11
BDBM722070 US20250059174, Example 132-12
BDBM722252 US20250059174, Example 281-132
BDBM727271 US20250090540, Example I-132
BDBM728524 US20250092056, Compound I-132
BDBM734895 US20250129069, Compound I-132
BDBM741956 US20250163057, Compound I-132
BDBM756183 US20250214997, Compound E-132
CHEMBL1929020 BDBM50484483 acs.jmedchem.1c00409_ST.132
CHEMBL4593937 US10829446, Compound 132 BDBM50527241
US10000476, Compound I-132 BDBM400773
US10144742, Compound I-132 BDBM305970
US10150728, Example I-132 BDBM306919
US10189809, Compound I-132 BDBM323863
US10206931, Example 132 BDBM50178202 CHEMBL3813701
US10221129, Example CA-132 BDBM359445
US10640495, Example I-132 BDBM441217
US10759796, Compound I-132 BDBM459131
US10774071, Example B-132 BDBM461665
US10793568, Compound I-132 BDBM465484
US10961247, Ex. No. 132 BDBM489524
US11001575, Example 132 CHEMBL4207587 BDBM50456350
US11026937, Compound I-132 BDBM501559
US11198695, Example I-132 BDBM528921
US11198695, Example II-132 BDBM529198
US11285156, Ex.# 132-1 BDBM544288
US11339144, Compound I-132 BDBM554682
US11407736, Compound I-132 BDBM562955
US11479560, Title WM-132 BDBM579283
US11555012, Compound I-132 BDBM589384
US11578084, Compound I-132 BDBM593849
US11685732, Compound I-132 BDBM606485
US11691962, Compound 1-132 BDBM607734
US11702418, Example 12-132 BDBM609641
US12331046, Compound I-132 BDBM750114
US12365696, Compound 132 CHEMBL4777901 BDBM50549748
US20230295130, Example T-132 BDBM619497
US20230399319, Example 2-132 BDBM640585
US20240101572, Example 2-132 BDBM661862
US20240308995, Example 1-132 BDBM697052
US20250019387, Table 1a.132 BDBM713483
US20250042857, Example B-132 BDBM718017
US20250059174, Example 132-1 BDBM722059
US20250059174, Example 132-13 BDBM722071
US20250059174, Example 132-14 BDBM722072
US20250059174, Example 132-15 BDBM722073
US20250059174, Example 132-16 BDBM722074
US20250059174, Example 132-17 BDBM722075
US20250059174, Example 132-4 BDBM722062
US20250059174, Example 132-5 BDBM722063
US20250059174, Example 132-8 BDBM722066
US20250059174, Example 132-9 BDBM722067
US20250162989, Compound I-132 BDBM741361
US8759532, 132 US8759532, 208 BDBM124465
US8933224, 132 BDBM142444 US8933224, 37
US9212153, 132,Ex. 97 BDBM195073
US9409866, 132 US9409866, 133 BDBM240417
US9458172, 111 US9458172, 132 BDBM252530
US9725442, Compound I-132 BDBM330597
US9790235, Number I-132 BDBM348879
US9796700, Compound I-132 BDBM351042
US9957235, 2-132-2 BDBM390474
WO2022090481, Example I-132 BDBM547911
BDBM408794 US10364238, Example 132 N-[(3-ethyl-2-fluorophenyl)methyl]-3-(methoxymethyl)-1-({4-[(2-oxopyridin-1- yl)methyl]phenyl}methyl)pyrazole-4-carboxamide US11001578, Example 132 US11084809, Example 132 US11198691, Example 132
(2S,5R)-5-(2-chlorophenyl)-1-(4-(naphthalen-2-yl)benzoyl)pyrrolidine-2-carboxylic acid US10017468, Compound 132 BDBM403881 US11072582, Compound 132 US10781171, Compound 132
BDBM154860 US8999957, Table 3, Compound 132
BDBM212556 US10155731, Example 133 US9278944, 132
BDBM221845 US9314468, Table 7, Compound 132
BDBM50516560 US10899738, Cpd. No 132 CHEMBL4592512
BDBM523803 US11136312, Compound SK-I-132
BDBM561595 US11390631, Example 132 Step b
BDBM564456 US11414384, Example 132 Isomer 1
Step a BDBM731691 US12268694, Example 132
US10442772, Example 2-132-1 BDBM415752
US11274090, Example 132 Isomer 1 BDBM542390
US11274090, Example 132 Isomer 2 BDBM542391
US11414384, Example 132 Isomer 2 BDBM564457
US11447465, Cmp No. T-132 BDBM571677
US12247004, Compound ANASIA-132-1 BDBM726311
US20240116892, Compound I-132-a BDBM665210
US20240116892, Compound I-132-b BDBM665211
US9944618, Compound ID No. 132 BDBM388596
US10799518, Compound 132 US10434112, Compound 132 1-(4-bromophenyl)-3-[4- (hydroxymethyl)-2,5-dioxo-4- (propan-2-yl)imidazolidin-1- yl]urea US10208071, Compound 132 BDBM350670
BDBM507932 tert-butyl 3-[7-chloro-4-(methylamino)- 2-oxo-1-phenylhydroquinazolin-5-yl- oxy]azetidinecarboxylate US11130759, Cpd. No. 132 US11084798, Cpd No 132 US11046691, Compound 132
US11352360, Example 132' US9884868, Example 132' BDBM282927 US10287295, Example 132' 6-(4-(4-fluorophenyl)-1-(3-hydroxypropyl)-1H- imidazol-5-yl)imidazo[1,2-b]pyridazine-3-carboxamide
US11618744, Example 132 US10851083, Example 132 BDBM475520 1-(5-Benzylamino-6-chloro-1H-benzoimidazol-2-yl)-1H-
US9708318, 132 US10251892, Example 132 US10632126, Example 132 US11173162, Example 132 BDBM262024 3-(2,6-difluoro-3,5-dimethoxyphenyl)-7-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(1-propyl-1H-pyrazol-4-yl)-3,4-dihydropyrido[4,3-d]pyrimidin-2(1H)-one
BDBM211138 US9247759, 5-70 US9247759, 5-132
BDBM219316 US9303033, I19, Table 33A, Compound 132
BDBM219458 US9303033, C25, Table 37A, Compound 132
BDBM360216 US9828339, Example 132 (R)-(1-methyl-
BDBM544540 US11286268, Compound 23 US11286268, Compound 132
BDBM563818 Roche-Dataset for PDE10A, Compound 132
BDBM594336 US11584747, Example 131 US11584747, Example 132
BDBM625499 US20230322789, Example 99 US20230322789, Compound 132
BDBM652306 US20240059675, Example 9 US20240101544, Example 132
BDBM655296 US11912703, Example 132 US11912703, Example 133
BDBM681572 US20240199605, Example 132 US20240199605, Example 131
BDBM99354 US8497281, 132 US9120769, 65 US9663470, 65
US10968215, Compound 132 BDBM490258 US10968215, Compound 133
US11344549, Example 85 BDBM555409 US11344549, Example 132
US11427567, Example 132 US11427567, Example 131 BDBM569486
US11999676, Compound 133 US11999676, Compound 132 BDBM679269
US20230322789, Example 132 US20230322789, Compound 164 BDBM625531
US20250025443, Compound 132 US20250025443, Example 6 BDBM713973
US20250025443, Example 132 US20250025443, Compound 204 BDBM714098
US8530652, 132 US8530652, 80 US8530494, 215 BDBM101553
US11319287, Example 132 US10669234, Example 132 BDBM445193 (S)-2-(5-(2-cyanophenyl)- isoindoline-2-carbonyl)- pyrrolidine-1-carbonitrile
US9617225, Example 132 2-Chloro-4-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-benzamide BDBM316304 US10294218, Example 132
US10851110, Example 132 US11466017, Example 132 US10280171, Example 132 3-{6-[4-(amino- methyl)-4-methyl- piperidin-1-yl]-1H- pyrazolo[3,4-b]- pyrazin-3-yl}-2- chloroaniline BDBM384209
US10034861, Example 132 US10512632, Example 132 BDBM279101 US10806718, Example 132 US10766893, Example S132 US11634416, Example 132 5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidazol-4-yl)methyl]-1-[1-methylpropyl]pyrazolo[4,3-b]pyridin-7-amine,enantiomer 2
US11498926, Example 132 US9624241, Example 132 BDBM318588 Methyl 3-[7-(3,5-dimethylisoxazol-4-yl)-2-oxo-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazin-4-yl]pyridine-2-carboxylate US10464947, Example 132
US10189829, Compound 132 US10227341, Compound 132 5-(tert-butyl)-N-(3- methyl-7-(2-((1-methyl- 1H-pyrazol-4- yl)amino)pyrimidin-4- yl)-2,3,4,5-tetrahydro- 1H-benzo[d]azepin- 1-yl)- 1,3,4-oxadiazole-2- carboxamide US11858926, Compound 132 BDBM324394 US10961237, Compound 132
US10450296, Example 132 BDBM376801 US11053215, Example 132 US9920032, Example 132 N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-5-fluoro-3-(2-(hydroxymethyl)morpholino)quinoline-8-carboxamide
US10738052, Example 132 BDBM388802 US11261191, Example 132 US9944645, 132 N-(1S)-1-[(Dimethylamino)carbonyl]-2,2-dimethylpropyl-2-fluoro-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide
US10968223, Compound 132 4-{5-[1-(5-Methylpyridin-2-yl)- 1H-pyrrolo[2,3-c]pyridin-2- yl]pyrimidin-2-yl}morpholine; tris(trifluoroacetic acid) US10766897, Compound 132 BDBM389961 US9951068, Compound 132
US9944647, Example 132 BDBM389023 US10800779, Example 132 US11401272, Example 132 4-{8-[5-(difluoromethyl)-6- methylpyridin-3-yl]-5-[4- (dimethylamino)piperidin-1- yl]imidazo[1,2-c]pyrimidin-7- yl}benzonitrile
1-((7-amino-2- US20240217978, Example 132 BDBM683477
BDBM195111 US9212153, 170,Ex. 132 US10336717, Compound 171
BDBM429460 med.21724, Compound 132 acs.jmedchem.1c00409_ST.345
US10000483, Compound II-7 BDBM400814 QL-X-132
US9296736, 132 US9593129, Example 133 US9296736, 133 BDBM215178
2-(3,4-dichloro-5-fluorobenzyl)- 1H-pyrrolo[3,2-b]pyridine-7- carboxylic acid US10174026, Example 132 US9738637, Example 132 BDBM320449
BDBM510272 US11439633, Example 132 US11077100, Example 132 (5R,8R)-N-(2,4- dichlorobenzyl)- 5-fluoro-8- hydroxy-5,6,7,8- tetrahydroquinoline- 5-carboxamide
US10202369, Example 132 BDBM319965 US10174016, Example 132 N-[1-(3-Chloro-5-fluoropyridin-2-yl)ethyl]-3-(5-methyl-1,3-thiazol-2-yl)-5-[(3S)-tetrahydrofuran-3-yloxy]benzamide US10472354, Example 132
US10934296, Example 132 (S)-4-(8-amino-3-(1-but-2- ynoylpyrrolidin-2-yl)imidazo[1,5- a]pyrazin-1-yl)-N-(4-phenylpyridin- 2-yl)benzamide US9758524, Example 132 US10239883, Example 132 BDBM340195
BDBM356979 US10214507, Compound 132 US10759777, Compound 132 (S)-1-((S)-3-(9H- carbazol-9-yl)-2- hydroxypropyl)-5- methylpiperidin-2- one
BDBM421542 US10995073, Example 132 US10508086, Example 132 Ethyl 3-[(2,4-dimethylthiazol-5-yl)methyl]-6-[(1-methylcyclopropyl)sulfamoyl]indole-1-carboxylate
US10617680, Example 132 US11020380, Example 132 BDBM437398 5-(1-ethyl-1H-pyrazol-4-yl)-1-methyl-4- phenylpyridin-2(1H)-one
BDBM109213 US9695170 133 US9695170 134 US9695170 131 US9695170 132
BDBM239851 Roche-Dataset for PDE10A, Compound 127 US9394311, 132
BDBM548871 WO2022098806, Compound 2-137 WO2022098806, Compound 2-132
US11479560, Title WM-126 US11479560, Title WM-132 BDBM579282
US11643417, Ex. No. 132 US11643417, Ex. No. 133 BDBM602120
US12012467, Compound ZBB-01-161 BDBM680893 US12012467, Example 132
US9328106, 132 US9328106, 114 US9328106, 122 US9328106, 133 BDBM227167
US9790235, Number I-132 BDBM348840 US9790235, Number I-93
BDBM38152 US10093640, Example 132 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-N-((4-phenoxyphenyl)sulfonyl)-1H-indole-2-carboxamide US10844032, Example 132
US11548890, Compound I-132 7-[[5-(4- hydroxy-1- piperidyl)-2- pyridyl]amino]-4-[6- (trifluorometh- yl)imidazo[1,2- a]pyridin-3- yl[isoindolin-1-one US11078201, Compound I-132 US11021481, Compound I-132 BDBM500473
US12065446, Example 132 US11319329, Ex # 132 US10934310, Ex # 132 BDBM485298 N-((1R,2S)-2-(2-(Dimethylamino)acetamido)cyclohexyl)-5-(*S)-(2- methyl-4-phenoxyphenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide
N-[5-(2,2-difluoroethoxy)pyridin-3-yl]-N-({5- [5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-1,3- thiazol-2-yl}methyl)ethane-1-sulfonamide US20240269137, Compound I-132 BDBM593441 US11578066, Compound I-132 US20230381148, Compound I-132
BDBM436798 6-(2,4-Difluorophenyl)-1-[(1-methylpyrazol-3-yl)methyl]-3H-imidazo[4,5- b]pyridin-2-one US10617676, Example 132 US11207298, Example 132
BDBM483687 4-chloro-1-(4-(3-(4- chlorophenoxy)- benzyl)- piperazine-1- carbonyl)-1H- pyrazole-3- carboxylic acid US11655217, Example 132 US10927105, Ex 132
US9662339, 132 BDBM326964 US11957671, Compound 132 1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridin-3-yl]benzyl}-1,4- diazepan-5-one
N-[3-[4-(5-cyanopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-2-[(2S)-1-[6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-4-yl]pyrrolidin-2-yl]acetamide US10870641, Example 132 US11014913, Example 132 BDBM431170 US10550105, Example 132
US10131667, Example 132 1-{[3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-methyl-2-oxo-2,3,4,7-tetrahydro-1H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-8-yl]methyl}piperidine-4-carbonitrile US11053246, Example 132 BDBM301316 US9611267, Example 132
US11130745, Example 132 BDBM470466 US11713304, Example 132 N-(2,6-dichlorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}benzamide US10815215, Example 132
US11608338, Example 132 1-(1,3-Dimethyl-1H-pyrazol- 4-yl)-7-methoxy-3-methyl-8- (2-methyl-3H-benzo- imidazol-5-yl)-1,3-dihydro- imidazo[4,5-c]quinolin-2- one US10457677, Example 132 US10975075, Example 132 BDBM418537
5-phenyl-1,3,4-oxadiazole-2-carbonitrile BDBM600901 US11634391, Compound 132
BDBM368716 US10227350, Compound 147 US10227350, Compound 131 US10227350, Compound 132
BDBM688018 US20240247015, Example 132 US20240247015, Example 131 US20240247015, Example 130
US10508105, Compound 132 BDBM422694 US10508105, Compound 43 US10508105, Compound 115
US10695337, Example 131 US9999619, Example 132 US11285140, Example 131 BDBM400377
US20230382904, Compound 131 US20230382904, Compound 121 US20230382904, Compound 132 BDBM637201
US8168651, Compound TABLE 17.132 BDBM165597 US9062043, Table 14, Compound 132
US10202381, Example 132 US10208039, Example 132 BDBM347125 2-(4-((3-(4-isopropylpiperazin-1- yl)phenyl)(methyl)amino)phenoxy) pyrido[3,4-d]pyrimidin-4-ol
US10577367, Example 132 1-(6-(1-(6-methylpyridin-2-yl)-1H-indazol-6-yl)pyridin-2-yl)butan-1-amine BDBM374120 US10246456, Example 132
US11434248, Compound 132 US10889591, Compound 132 4-(4-methoxy-4-methylpiperidin-1-yl)-2-oxo-6-vinyl-1,2-dihydro-1,7-naphthyridin-3-carbonitrile BDBM477992
US10874640, Compound 132 US20230270719, Compound 132 (R)-N-(3-Chloro-4-fluorophenyl)-6-methyl-7-(2-oxo-2-((1,1,1-trifluoro-3-hydroxy-2-methylpropan-2-yl)amino)acetyl)-2,3-dihydro-1H-pyrrolizine-5-carboxamide BDBM400148 US10328053, Compound 132
BDBM361540 US11046689, Example 132 (S)-3-((1R,3R)- 1-(2-(2-((3- fluoropropyl) amino)ethoxy)- 3- methylpyridin- 4-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid US10590132, Example 132 US10221173, Example 132
(R)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-2-morpholinothiazole-4-carboxamide BDBM309986 US11046713, Example 132 US9657003, 132
BDBM379228 US10266549, Example 132 N-(4-((2-((2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acetamide US10774092, Example 132
US10485800, Example 132 US9814704, Example 132 BDBM354855 Preparation of 3-[2-oxo-5-(3,4,5-trimethoxy-phenyl)-1,2-dihydro-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-benzamide
US10544130, Example 132 (R)-2'-amino-3'-cyano-N4- (pyrrolidin-3-yl)-2-(1H-tetrazol- 5-yl)-[1,1'-biphenyl]-3,4- disulfonamide US10221163, Example 132 BDBM360976
US11046712, No 132 US10336775, Example 132 (S)-5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-1,3,4-thiadiazol-2-amine BDBM408228
(1R,3S,5R)-2-(2-(3- acetyl-5-(2- methylpyrimidin-5-yl)- 1H-indol-1-yl)acetyl)- N-(6-bromopyridin-2- yl)-2- azabicyclo[3.1.0] hexane-3-carboxamide US9796741, cmp No. 132 US10287301, Compound 132 BDBM354234 US10822352, Comp No. 132
(S)-1-(4-(3-amino-6-(2- BDBM394531 US10308614, Example 132
BDBM388523 US9944618, Compound ID No. 57 US9944618, Compound ID No. 132
US11447465, Cmp No. T-132 US11447465, Cmp No. T-76 BDBM571623
US11845724, Compound I-132 (S)-4-fluoro-N-(1-(4- BDBM642017
BDBM513264 N-((1R,2R)-2-hydroxycyclohexyl)-6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-yl)methoxy)pyridine-3-carboxamide US11091471, Example 132 US20240279218, Example 132
BDBM615212 US20230271945, Compound 132 3-[5-fluoro-2-phenyl-7-(trifluoromethyl)-1H-indol-3-yl]-N-[(3S,4R)-4-hydroxy-2-oxo-pyrrolidin-3-yl]propanamide (132)
US10442772, Example 2-132-2 (�) 4-[(2-{[4-(trifluoromethoxy)phenyl]amino}-1-[(cis)-3,3,5-trimethylcyclohexyl]-1H-benzimidazol-5-yl)oxy]butanoic acid US9957235, 2-132 BDBM390472
US20230357269, Example 132 (13R)-16-fluoro-13-methyl-8,14-dioxa-10,19,20- BDBM634447
5-[[5-[2-methoxy-4-[[[(3S)-tetrahydrofuran-3-yl]amino]methyl]phenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile hydrochloride US10010547, Example 132 BDBM402022 US10973817, Example 132
US10647720, Ex. # 132 BDBM322762 US10183944, Example 132 3-(1-(4-((5-oxo-2-phenyl-5,6- dihydropyrimido[4,5-d]pyridazin-4-yl) amino)phenyl)piperidin-4-yl)propanoic acid
BDBM267356 3-chloro-5-((1-((2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile US9718819, 132 US10189831, Example 132
BDBM291817 N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-(1,3,5-trimethyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine US9580437, Example 132 US11207325, Example 132
US10246453, Example 132 (S)-2-fluoro-5-methyl-4-(methyl(1-((5-methylfuran-2-yl)methyl)pyrrolidin-3-yl)amino)-N-(thiazol-4-yl)benzenesulfonamide BDBM373865 US10815229, Example 132
US11390618, Example 132 (R)-1-(6-(3-((5-chloropyrimidin-2- yl)amino)pyrrolidine-1-carbonyl)-3,4- dihydroisoquinolin-2(1H)-yl)prop-2- en-1-one BDBM479092 US10894788, Example 132
US11479551, Example 4-132 US11492351, Example 4-132 BDBM579015 2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin-6-yl)-1-methyl-1H- pyrazol-5-yl)-5-chloro-4-methylbenzonitrile
US10570121, Example 132 US10570121, Example 133 US10570121, Example 134 US10570121, Example 135 BDBM435626
US11111242, Example 50 BDBM316523 US20250134869, Example 132 US9617258, Example 11 US9617258, Example 50
WO2022086828, Example 54 WO2018148626, Example 151 WO2022086828, Example 151 WO2022086828, Example 132 BDBM534327
BDBM484333 (S)-l-(2-(1-(4-((3,4- difluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)but- 2-yn-1-one US10933063, Compound 132 US11554118, Compound 132
US11078199, Cpd 132 8-(2-((1-acryloylpiperidin-4-yl)(ethyl)amino)ethyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8H)-one US9567334, Example 132 BDBM287228
(S)-2-((1- ([1,2,4]triazolo[1,5- a]pyridin-7-yl)-8,9- dihydro-7H-6-oxa- 2,9a- diazabenzo[cd]azulen- 4-yl)amino)-2- cyclopropylacetamide BDBM272827 US10065970, Compound 132 US10435414, Compound 132
BDBM609171 US11702414, Example 132 +-7-(5-(5-(trans-2-(2-hydroxypropan-2-yl)cyclopropyl)-1,3,4-thiadiazol-2-yl)-4-(isopropylamino)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile (Example 132)
US11485745, Example 132 N-[[6-(4-isoxazol-5-yl-1-methyl- pyrazole-3-carbonyl)-6- azaspiro[2.5]octan-2- yl]methyl]furo[2,3-c]pyridine-2- carboxamide US10730889, Example 132 BDBM455538
BDBM267033 Methyl 2-(acetyloxy)-4-{[(4,5-dichlorothiophen-2-yl)sulfonyl]amino}benzoate US9718809, 132
BDBM487339 US10953012, Example 132 3-benzyl-5-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7
4-(5-(3-cyano-6-(1-methyl- 1H-pyrazol-4- yl)pyrazolo[1,5-a]pyridin- 4-yl)pyridin-2-yl)-N,N- dimethylpiperazine-1- carboxamide BDBM284122 US10174027, Example 132 US10023570, Example 132
BDBM425059 N-((S)-5-((1S,2R)-2-(4- fluorophenyl)cyclopropylamino)-1-(4- methylpiperazin-1-yl)-1-oxopentan-2-yl)-4- (1H-1,2,3-triazol-1-yl)benzamide US11230534, Example 132 US10519118, Example 132
N-((3S,4R)-4-Fluoro-1-methylpyrrolidin-3-yl)-5-(2-methyl-4- phenoxyphenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide; US10800792, Example 132 BDBM467480 US10822348, Example 132
US10092575, Example 132 6-(4-Chloro-2-fluorobenzyl)-9-(pyrimidin-2-ylmethyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5 (6H)-one BDBM289644 US10376514, Example 132
{4-[4-({[3- (difluoromethoxy)phenyl]methyl} carbamoyl)-1H-1,2,3-triazol-1-yl] butyl}-N-{[4-(trifluoromethyl) pyridin-2-yl]methyl}-1H-1,2,3- triazole-4-carboxamide US10344025, Example 132 US11370786, Example 132 BDBM404788
BDBM192918 US10526329, Compound 132 US9670204, 132 1-(4-(2-ethyl-3-((4-(4-fluorophenyl)thiazol-2-yl)(methyl)amino)imidazo[1,2-a]pyridin-6-yl)piperidin-1-yl)-3-(methylamino)propan-1-one
BDBM517991 US11111237, Example 132 US11725001, Example 132 4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxy-propyl]-1-methyl-8-(1-methylpyrrolidin- 3-yl)oxy-2,3-dihydro-1,4-benzodiazepin-5-one
US10961200, Compound 132 4-((5-((1H-tetrazol-5- yl)methyl)-1-(4- (hydroxymethyl)thiazol- 2-yl)-3-phenyl-1H- pyrazol-4- yl)methyl)ben- zenesulfonamide (M + H)+ = 509 US11247971, Cmpd ID 132 BDBM488754
(R)-1-(2-(2-(3′-(7-cyano-5-(((R)-3-hydroxypyrrolidin-1-yl)methyl)benzo[d]oxazol-2-yl)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)-4,6-dihydro-5H-pyrrolo[3,4-d]oxazol-5-yl)-2-oxoethyl)pyrrolidine-3-carboxylic acid US10800768, Example 132 US10308644, Example 132 BDBM395520 US11339149, Example 132
2-[4-({[(2- hydroxyphenyl)methyl]amino} methyl)-3,5- dimethoxyphenoxymethyl]-6- phenylbenzonitrile BDBM365880 US9872852, Example 132
3-(5-(1,3,4-oxadiazol-2-yl)pyridin-3-yl)phenyl tetradecylcarbamate BDBM734157 US20250129027, Example 132
3-({[(1R)-6-[(1,3-dihydro-2-benzofuran-5-yl)(methyl)amino]- BDBM293790 US10106534, Example 132
3-{[trans-4-phenyl-1-(propylsulfonyl)pyrrolidin-3-yl]amino}benzonitrile BDBM308624 US9656955, Example 132
BDBM246227 US9434690, 135 US9434690, 134 US9434690, 133 US9822102, Example 135 US9434690, 132 US10183932, Example 135
BDBM396507 US9981909, Example 132 5-[1-[2-(Azetidin-3-yloxy)-4-chloro-phenoxy]-ethyl]-thiazole
BDBM736648 US20250136570, Compound 132 (R)—N-[2-amino-5-(4-fluorophenyl)phenyl]-4-(methylsulfonimidoyl)benzamide 
US8609678, 4-(bis(2,4-difluorophenyl)(methoxy)methyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [132] BDBM110079
US9670212, 132 N-5-{[3-(2-methylphenyl)quinolin-2-yl]methyl}pyrimidin-4,5-diamine BDBM195744
BDBM314953 US9611277, Example 132 (6-methyl-3-(2H-1,2,3-triazol-2-yl)pyridin-2-yl)((1S,4R,6R)-6-((5-methylpyrimidin-2-yl)oxy)-2-azabicyclo[2.2.1]heptan-2-yl)methanone US10183953, Example 132
US10239876, Example 132 US10435407, Example 132 BDBM372109 3-[2-[4-Methyl-3-(trifluoromethyl)piperazin-1-yl]-2-oxoethyl]-1-phenyl-8-(1H-pyrazolo[3,4-b]pyridine-5-carbonyl)-1,3,8-triazaspiro[4.5]decan-4-one
US10654853, Example 132 (R)-7′-(5-Methyl-H-indazol-4-yl)-2′-oxo-1′,4′-dihydro-2′H-spiro[pyrrolidine-3,3′-quinoline]-1-carbonitrile US11236092, Example 132 BDBM443359
US10421742, Example 132 BDBM413739 US11180471, Example 132 2-{4-[5-Chloro-2-(4,5-dihydro-1,2-oxazol-3-yl)phenyl]-5-methoxy-2-oxopyridin-1(2H)-yl}-N-(2-methyl-2H-indazol-5-yl)pentanamide (Racemate)
(R)-N-(6-chloropyridin-3-yl)-6- (1-methoxyethyl)isoquinolin- 1-amine BDBM660747 US20240101531, Example 132
2-[3-Bromo-2-(2-oxo-1,3-dihydrobenzimidazol-5-yl)phenyl]acetonitrile; BDBM435959 US10611730, Example 132
3-(3-amino-2H-indazol-5- yl)-2-(1H-tetrazol-5- yl)benzenesulfonamide BDBM262280 US9708336, 132
BDBM430202 US10538491, Compound 132 4-(4-fluorophenyl)-5-(((tetrahydro-2H-pyran-4-yl)methyl)amino)picolinamide
BDBM613391 1-[1-(cyanomethyl)-4-(3,3,3- trifluoropropylamino) cyclohexyl]-3- (cyclopropanecarbonylamino) pyrazole-4-carboxamide US11731943, Example 132
BDBM377438 US10676434, Example 131 US11053197, Example 132 5-((S)-3-(But-2-ynamido)piperidin-1-yl)-6-fluoro-2-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (Single Isomer) US10266491, Example 131 US10266491, Example 132
(1-cyclobutylpiperidin-3-yl)(6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)methanoe BDBM383619 US10280149, Example 132
(R)-N-(2,2-dimethylquinuclidin-3-yl)-7-phenylbenzo[b]thiophene-2-carboxamide BDBM322368 US10183938, Compound (R)-132
2-[6-(4-Methyl-2-thienyl)pyrrolo[3,2-b]pyridin-1-yl]-1- BDBM409223 US10377753, Example 132
2-methyl-5-({2- [(pyrimidin-5- ylmethyl)amino] pyrimidin-5- yl}carbonyl) benzonitrile BDBM395121 US10308615, Example 132
2-oxo-N-(1,2,3,4- tetrahydronaphthalen-1-yl)- 6-(trifluoromethyl)-1,2- dihydropyridine-3- carboxamide BDBM667374 US11957687, Compound 132
BDBM231643 US9556139, 132 7-(4-(1-(4-Chlorophenyl)propan-2-ylcarbamoyl)phenoxy)-6-cyanochroman-4-carboxylic acid
BDBM443047 2-((3-(benzyloxy)phenyl)amino)-N- hydroxy-1H-benzo[d]imidazole-6- carboxamide US10654814, Example 132
BDBM499436 4-((3-(2-(cyclopropylmethoxy) pyridin-4-yl)- 5-fluorophenoxy)methyl)-N- (methylsulfonyl)benzamide US11020381, Example 132
BDBM534659 N-(6-(2-ethyl-6-methylpyrimidin-4-yl)-6-methyl-5-oxo-5,6,7,8- US11229636, Compound 132
BDBM543123 US11279687, Compound 132 3-{4-[(2-methoxypyridin-3- yl)sulfamoyl]phenyl}-1-(pyridin-3- ylmethyl)urea
BDBM551024 6-[2-Cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-3-yl]-3H-1,3- US11312712, Example 132
BDBM556897 US11352339, Example 132 (S)-6-(2-(1-Cyanopyrrolidin-2-yl)benzo[d]oxazol-6-yl)picolinonitrile
BDBM557080 US11352340, Example 132 N-(2'-(5- Phenyl-1H- imidazol-2- yl)-3,4'- bipyridin-5- yl)benzamide
US10266526, Compound 132 ethyl 1-(L-alanyl)-4-((2-oxoindoline-5-carboxamido)methyl)piperidine-4-carboxylate BDBM378002
US9593105, 132 BDBM242131 US9415055, 2,4-dichloro-N-(2-morpholino-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)benzamide
US9663460, Example 132 BDBM327328 N-{5-chloro-2-[(pyridin-3-ylmethyl)sulfonyl]-phenyl}-1-benzofuran-2-sulfonamide
US9732093, Compound 132 2-[3-(5-Aminopyrazin-2-yl)-6- cyclobutyl-2-fluorophenoxy]-5- (methylsulfonyl)benzonitrile BDBM335623
(S,E)-1-(2-(Hydroxymethyl)-4-((2-methyloxazol-4-yl)methyl)piperazin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one BDBM322036 US9763957, Example 132 US10183025, Example 132
(S)-quinuclidin-3-yl (6-(3-isopropoxyphenyl)-2,2-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)carbamate US12338237, Example 132 BDBM753374
3-(4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-N-(3,3- difluorocyclobutyl)-4-methylbenzenesulfonamide BDBM421096 US10479795, Example 132
5-(pyridin-2- ylamino)-3-(4- ((p-tolylmethyl) sulfonamido) phenyl)-1H- pyrazole-4- carboxamide BDBM725382 US20250074891, Compound 132
6-(2-(4-Fluorophenoxy)-2- methylpropyl)-2-thia-6- azaspiro[3.4]octane 2,2-dioxide BDBM707060 US20240400579, Example 132
BDBM401517 6-carbamoyl-2-(4-(2- (morpholinomethyl)-4- (trifluoromethyl)phenoxy)phenyl) pyrimidine-4-carboxylic acid US10005768, Compound 132
BDBM432269 US10577360, Example 132 N-[6-(4-Methoxyphenyl)pyrazin-2-yl]-N-(1-methylpiperidin-4-yl)thiophene-2-
BDBM568985 4-cyano-N-(3-(furan-3-yl)- 1H-indazol-5-yl)pyrimidine- 2-carboxamide US11427558, Example 132
BDBM580920 5-(4-(4-chloro-3-(trifluoromethyl)phenoxy)- 6-morpholinopyridin-2-yl)pyrimidin-2- amine US11492348, Compound 132
BDBM612149 N-[5-(3-fluorophenyl)-2- methyl-[1,2,4]triazolo[1,5- c]pyrimidin-7-yl]acetamide US11718622, Compound 132
BDBM612442 (S)-or (R)- 4-((dimethylamino)methyl)-N'-(4- fluoro-2,6-diisopropyl- phenylcarbamoyl)benzene- sulfonimidamide US11724992, Example 132
BDBM624555 US11780849, Compound 132 (2-hydroxy-2-methylpropyl)(imino){4-[(7- methoxyquinolin-4-yl)oxy]phenyl}-lambda6- sulfanone
US10294212, No. 132 5-Chloro-N3-(4- fluoro-3- (trifluoro- methyl)phenyl) benzo[b] thiophene-2,3- diamine BDBM387524
US11420935, Compound 132 BDBM566589 (S)-N-(1-(1-isopropylazetidin-3- yl)ethyl)-5-(4- (trifluoromethyl)phenoxy)-2- naphthamide
US11787802, Example 132 3-Methoxy-N-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)isonicotinamide BDBM627126
US20240376090, Compound 132 N-[3-(3,5-dimethylisoxazol-4-yl)-4-(1-methylazetidin-3-yl)oxy- phenyl]cyclopropanecarboxamide BDBM704758
US9688684, Compound 132: 7-(4-Fluoro-benzyl)-8-(4-isopropoxy-phenyl)-5,6,7,8-tetrahydro-tetrazolo[1,5-a]pyrazine BDBM175935
ethyl 4-((3-(2-cyanoethyl)cyclohexyl)amino)-1H- pyrrolo[2,3-b]pyridine-5-carboxylate BDBM493032 US10981906, Example 132
(1R,3S,5R)-2-(2-(3-acetyl-7-methyl-5-(2- methylpyrimidin-5-yl)-1H-indazol-1- yl)acetyl)-N-(6-bromo-3-methylpyridin-2- ((ethylamino)methyl)-2- azabicyclo[3.1.0]hexane-3-carboxamide US11084800, Cpd No. 132 BDBM511819 US11708351, Compound 132