Simple Search Results

Query String: Paclitaxel ABT-199

glucose-dependent insulinotropic receptor [1-198]/[199-335]

BDBM50162774 ABT-199 US11420968, Example ABT-199 Venetoclax
US10377755, Example ABT-199 US20240166646, Example ABT-199 US11369599, Compound 369 BDBM60828 US10213433, Compound 5 US11590126, Example ABT-199 BDBM189459 US11318134, Example ABT-199 US11718611, Example T-7 US9174982, 369 ABT-199 US20240043404, Example 369
US10961228, Example ABT-494 BDBM50503287 Rinvoq ABT-494 Upadacitinib
ABT-229 BDBM86685
US9695183, 199 US9475819, 199 BDBM164069 US9637496, 199 US9062078, 199
BDBM747490 US12325697, Compound ABT-2
US10377755, Example ABT-263 BDBM417035
US10245267, Example 199 US9242969, 199 US9694016, 199 BDBM202846 US10709712, Example 199
USRE48841, Example 199 US11667644, Example 199 US8653263, 199 US9586962, Example 199 BDBM118546 US11059828, Example 199
US10640534, Compound 199 US9850277, Compound 199 BDBM363712 US10717764, Compound 199 US11667673, Compound 199 US10689414, Compound 199 US11021515, Compound 199
BDBM150525 US10238633, Example 199 US9713606, 199 US8987249, 199
BDBM127826 US8791123, 199 US9782415, Example 199 US10251889, Example 199 US10758542, Example 199
US10112937, Example 199 US10150765, Example 199 US9464084, 199 BDBM254302 US10703749, Example 199
US10137124, Example 199 US10112942, Example 199 US10172851, Example 199 BDBM296465 US10555944, Example 199 US10953005, Example 199
US11648243, Example 199 US10144734, Example 199 US10172845, Example 199 US10441581, Example 199 US10881652, Example 199 BDBM305183
US10307413, Compound 199 US10980794, Cmpd No 199 BDBM178155 US10391089, Compound 199 US9675614, 199
US11111235, No. 199 US11591316, Compound 199 US9932325, Example 199 BDBM384513 US10590114, No. 199
US11220509, Example 199 BDBM513838 US11091495, Example 199 US11485738, Example 199 US20240398811, Example 199
taxol CHEMBL428647 BDBM50001839 PACLITAXEL
BDBM241355 US10479788, Example 199 US11046688, Example 199 US9409907, 199
BDBM268167 US9549932, 199 US10772893, Example 199 US11529356, Example 199
US10183932, Example 199 US9434690, 199 BDBM246293 US9822102, Example 199
US9321760, 199 US9662330, Compound 199 BDBM224521 US10080750, Compound 199
US9452980, 199 US10501411, Example 199 US11697636, Example 199 BDBM250289
US9688672, Example 199 US9434719, 199 BDBM247600 US10112931, Example 199
US9745328, Compound 199 BDBM168800 US9079866, 199 US9884878, Compound 199
ABT-267 BDBM50453112 Ombitasvir CHEBI:85183
CHEBI:62880 BDBM50445857 ABT-888 Veliparib
Pibrentasvir ABT-530 A-1325912.0 BDBM50453100
US11590126, Example ABT-263 US11318134, Example ABT-263 ABT-263 US11344546, Example ABT-263 US11420968, Example ABT-263 (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enyl)methyl)piperazin-1-yl)-N-(4-(4-morpholino-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)benzamide BDBM50270877 CHEMBL443684
BDBM145012 US8952157, 199 US9303025, 199
BDBM71052 US9546164, 199 US9694002, 199
US10047103, 199 US9688695, 199 BDBM176166
US8921389, 199 BDBM141740 US9695170 199
US9040714, 199 US9693992, 199 BDBM160469
US9682971, 199 BDBM165164 US9067917, 199
US9732066, 199 BDBM197599 US9216968, 199
BDBM292344 US9745310, Example 199 US10100057, Example 199 US11046702, Example 199
BDBM431254 US10870641, Example 199 US10550105, Example 199 US11014913, Example 199
US10028961, Compound 199 US10946023, Compound 199 US10172864, Compound 199 BDBM280046
US10533001, Example 199 US9868729, Example 199 BDBM365483 US11414410, Example 199
US10807986, Example 199 Ex. Cpd. 199 US11046696, Compound 199 BDBM311747
US10988451, Example 199 US10703733, Example 199 BDBM449586 US11643400, Example 199
US11530183, Example 199 BDBM454206 US10717708, Example 199 US11186544, Example 199
US11702424, Example 199 US10793579, Example 199 BDBM403048 US10329302, Example 199
US20240101536, Example 199 US12240835, Example 199 BDBM477851 US10889571, Example 199
US20250017938, Compound 002-199 US10226449, cpd 199 BDBM244590 US9428502, 199
US9777003, Example 199 BDBM343600 US10442803, Example 199 US11091484, Example 199
US9999619, Example 199 US11285140, Example 199 US10695337, Example 199 BDBM400444
BDBM171565 US9085576, 199 US9611261, Example 199
BDBM232653 US9604984, Example 199 US9346815, 199
BDBM241567 US9409908, 199 US9951071, Example 199
BDBM244964 US9422293, 199 US9738649, Example 199
US10369153, Compound 199 US9346810, 199 BDBM228641
US11547697, Compound 199 BDBM127396 US9682141, 199
US8916576, 199 US10570123, Example 199 BDBM140996
US9073922, 199 BDBM167712 US9796708, Example 199
US9540323, 199 BDBM260992 US9540323, example 199
US9593129, Example 199 US9296736, 199 BDBM215239
US9682966, 199 US10118915, Compound 199 BDBM156209
US9732093, Compound 199 US9073876, 199 BDBM167115
BDBM397243 US10828300, Compound I-199 US9987276, Compound I-199 US10596172, Compound I-199 US11351168, Compound I-199
BDBM137131 US20250017938, Compound 001-199 US8871790, 199
BDBM273416 US10478424, Example 199 US10071079, Example 199
BDBM280654 US10030020, Example 199 US10781211, Example 199
BDBM284189 US10023570, Example 199 US10174028, Example 199
BDBM348476 US9790229, Compound 199 US10577374, Compound 199
BDBM356849 US10214492, Example 199 US11292767, Example 199
BDBM362637 US10562916, Compound 199 US9834564, Compound 199
BDBM456473 US11510915, Example 199 US10723742, Example 199
BDBM561662 US11390631, Example 199 US12268694, Example 199
BDBM573617 US11453683, Example 199 US20230279025, Example 199
BDBM586022 US11530237, Compound 199 US11542297, Compound 199
US10105367, Example 199 US10376514, Example 199 BDBM292913
US10125118, Example 199 BDBM298793 US10947215, Example 199
US10259811, Example 199 US10072001, Example 199 BDBM277022
US10301317, Example 199 BDBM318243 US9624228, Example 199
US10323000, Compound 199 US10676433, Compound 199 BDBM398258
US10435405, Example 199 US10934288, Example 199 BDBM414782
US10562891, Example 199 BDBM434277 US11008308, Example 199
US10584135, Example 199 BDBM382318 US10273244, Example 199
US10597367, Example 199 BDBM393902 US9969726, Example 199
US10774053, Compound 199 BDBM461066 US11352329, COMPD # 199
US10995073, Example 199 US10508086, Example 199 BDBM421609
US11053219, Example 199 BDBM515749 US11731956, Example 199
US11396512, Example 199 BDBM467207 US10800783, Example 199
US11555029, No. 199 BDBM452059 US10710986, Example 199
US12070457, Compound 199 BDBM578351 US11478474, Compound 199
US8604016, 199 US9938267, Cmpd ID 199 BDBM108624
BDBM399716 US10793574, Compound I-199 US11220508, Compound I-199 US10323036, Compound I-199
BDBM423744 US11046698, Compound I-199 US10577373, Compound I-199 US10508120, Compound I-199
US9688629, 198 US9688629, 199 US9688629, 197 US10604504, Example 199 US11623921, Example 199 BDBM165586
ABT-348 BDBM50381716 ILORASERTIB US8722890, 1 US8722890, 2
Delafloxacin BDBM50560872 WQ-3034 ABT-492 RX-3341
US10336717, Compound 199 BDBM195138 US9212153, 199,Ex. 159
US10988476, Compound I-199 BDBM444618 US10662186, Compound 199
US10392391, Compound I-N-199 US11370798, Cmpd. # I-N-199 US11117900, Compound I-N-199 US20230271963, Compound I-N-199 US10787452, Compound I-N-199 BDBM411766
BDBM442238 US11396508, Compound I-199 US10647713, Compound I-199
US10597377, Compound 2-199 BDBM405730 US10351547, Compound 2-199
US10633389, Example 199-3 US20230279020, Example 199-3 BDBM440533
US11345716, Compound III-199 BDBM476787 US10870660, Compound III-199
US12221453, Compound I-199 BDBM565633 US11414431, Compound I-199
US20230279020, Example 199-1a BDBM439890 US10633389, Example 199-1a
US9732060, Compound R-199 US10065941, Compound R-199 BDBM271884
US9802960, Compound I-199 US9751854, Compound I-199 BDBM338023
BDBM311342 US10723734, Example 199 US10544120, Example 199 (S)-1-((2′,5-bis(difluoromethyl)-[3,4′-bipyridin]-6-yl)oxy)-2,4-dimethylpentan-2-amine US10155760, Example 199 US10351563, Example 199 US9902722, Example 199 US10981910, Example 199
BDBM103222 US8541407, 199
BDBM105162 US8569281, 199
BDBM10637 US8846719, 199
BDBM109461 US8604061, 199
BDBM110425 US8613914, 199
BDBM113483 US8633204, 199
BDBM117260 US9682940, 199
BDBM121760 US8722692, 199
BDBM125804 US8772305, 199
BDBM129110 US8802674, 199
BDBM132452 US8841312, 199
BDBM134197 US8846689, 199
BDBM13813 US8846929, 199
BDBM140767 US8912224, 199
BDBM145420 US8952169, 199
BDBM147362 US8957093, 199
BDBM151763 US8987445, 199
BDBM152005 US8987457, 199
BDBM153053 US8993616, 199
BDBM156148 US9018214, 199
BDBM156772 US9029559, 199
BDBM161761 US9682976, 199
BDBM166903 US9073870, 199
BDBM169850 US9073940, 199
BDBM170771 US9085555, 199
BDBM175652 US9688680, 199
BDBM180650 US8772323, 199
BDBM181996 US9145380, 199
BDBM182498 US9145392, 199
BDBM186532 US9163021, 199
BDBM188659 US9169246, 199
BDBM189636 US9174982, 199
BDBM196125 US9206232, 199
BDBM199952 US9227930, 199
BDBM200208 US9234000, 199
BDBM201433 US9187424, 199
BDBM201768 US9233979, 199
BDBM203038 US9242970, 199
BDBM203641 US9221809, 199
BDBM204489 US9242996, 199
BDBM205730 US9255090, 199
BDBM208732 US9266876, 199
BDBM209358 US9266883, 199
BDBM210487 US9290451, 199
BDBM213607 US9278981, 199
BDBM215006 US9296734, 199
BDBM220610 US9296741, 199
BDBM226506 US9328096, 199
BDBM229872 US9334269, 199
BDBM230013 US9556135, 199
BDBM231812 US9340517, 199
BDBM234071 US9353090, 199
BDBM236446 US9365576, 199
BDBM249771 US9447038, 199
BDBM252802 US9458176, 199
BDBM255240 US9475817, 199
BDBM255448 US9481682, 199
BDBM302287 US9598415, 199
BDBM327653 US9663469, 199
BDBM47240 US9012651, 199
BDBM88311 US9695118, 199
BDBM99697 US8501936, 199
US8481733, 199 BDBM98387
US8486940, 199 BDBM64995
US8497265, 199 BDBM98873
US8530648, 199 BDBM102262
US8569308, 199 BDBM104779
US8575186, 199 BDBM104420
US8598345, 199 BDBM107294
US8623889, 199 BDBM112201
US8637532, 199 BDBM116515
US8759532, 199 BDBM124522
US8772480, 199 BDBM125369
US8778951, 199 BDBM126389
US8791131, 199 BDBM127425
US8791257, 199 BDBM127343
US8796244, 199 BDBM128611
US8802673, 199 BDBM129557
US8815926, 199 BDBM129918
US8822448, 199 BDBM130772
US8846698, 199 BDBM134736
US8853258, 199 BDBM135547
US8859596, 199 BDBM135910
US8871934, 199 BDBM137606
US8901315, 199 BDBM140104
US8969325, 199 BDBM143998
US8969341, 199 BDBM143734
US9012443, 199 BDBM154190
US9023865, 199 BDBM157358
US9023882, 199 BDBM157915
US9034866, 199 BDBM158724
US9051280, 199 BDBM162241
US9066954, 199 BDBM164456
US9067871, 199 BDBM164722
US9067922, 199 BDBM165860
US9067949, 199 BDBM166342
US9079906, 199 BDBM169643
US9120812, 199 BDBM178414
US9125913, 199 BDBM178634
US9150526, 199 BDBM183936
US9150577, 199 BDBM184318
US9156845, 199 BDBM185576
US9163007, 199 BDBM185859
US9169252, 199 BDBM187649
US9181272, 199 BDBM191429
US9206199, 199 BDBM196094
US9216988, 199 BDBM197929
US9260439, 199 BDBM207222
US9265773, 199 BDBM208254
US9283222, 199 BDBM214137
US9296745, 199 BDBM215661
US9302989, 199 BDBM215999
US9321756, 199 BDBM224939
US9328106, 199 BDBM227248
US9346798, 199 BDBM231452
US9388189, 199 BDBM236993
US9394297, 199 BDBM238553
US9434711, 199 BDBM248345
US9434725, 199 BDBM248968
US9452986, 199 BDBM250895
US9458110, 199 BDBM252127
US9458171, 199 BDBM253239
US9481672, 199 BDBM256021
US9493446, 199 BDBM257730
US9505765, 199 BDBM254975
US9675593, 199 BDBM169546
US9688629, 199 BDBM165610
US9693997, 199 BDBM70675
US9695149, 199 BDBM102361
BDBM415849 US10442772, Example 2-199-1 US10442772, Example 2-199
CHEMBL4070674 US11208415, Example I-199 US10533010, Example I-199 BDBM50244129
US10174016, Example 200 BDBM320033 US10472354, Example 199 US10202369, Example 199
US10273259, Example 198 US10273259, Example 199 US10711020, Example 199 BDBM382489
US10730877, Example 199 BDBM427741 US10544143, Example 174 US11053244, Example 199
US11718626, Compound T-199 US11053253, Cmp No. T-199 BDBM516778
BDBM390569 US9957235, 2-199-2 US9957235, 2-199-1 US10442772, Example 2-226-2 US9957235, 2-199
US10646492, Example 199 US10092570, Example 199 US11433071, Example 199 US9730939, Example 199 5-(3-(1-(4-amino-3-methyl-1H- pyrazolo[3,4-d]pyrimidin-1- yl)ethyl)-5-chloro-2-ethoxy-6- methylphenyl)-N- methylpicolinamide3 US10376513, Example 199 BDBM261176 US9707233, 199
A-12825760 Glecaprevir A-1282576 A-1282576.0 ABT-493 BDBM50573891
ABT-333 Dasabuvir sodium monohydrate BDBM50549803 CHEBI:85182 Exviera Dasabuvir
BDBM105689 US8575197, I-199
BDBM106286 US8575197, II-199
BDBM116050 US8633183, E-199
BDBM117519 US8653087, III-199
BDBM122729 US8735386, I-199
BDBM147875 US8962608, 28-199
BDBM268795 US9718825, Example 199
BDBM279374 US10035760, Example 199
BDBM281259 US10022354, Example 199
BDBM294510 US10111875, Compound 199
BDBM294722 US10112899, Example 199
BDBM300948 US10131658, Compound 199
BDBM326502 US9662327, Compound 199
BDBM331778 US9725465, Example 199
BDBM339338 US10201546, Example 199
BDBM339754 US10202339, Compound 199
BDBM341965 US9771320, Example 199
BDBM348280 US9790228, Compound 199
BDBM357455 US10214519, Example 199
BDBM371092 US10239843, Example 199
BDBM371959 US10239870, Example 199
BDBM390312 US9951086, Example 199
BDBM406024 US10351558, Example 199
BDBM438632 US10618903, Example 199
BDBM451369 US10709709, Example 199
BDBM451599 US10710967, Example 199
BDBM453842 US10730863, Example 199
BDBM462587 US10766903, Example 199
BDBM480982 US10906888, Example 199
BDBM484948 US10934302, Example 199
BDBM489945 US10966980, Example 199
BDBM490322 US10968215, Compound 199
BDBM491252 US10975056, Example 199
BDBM499294 US11014963, Example 199
BDBM501280 US11021493, Example 199
BDBM512606 acs.jmedchem.1c00409_ST.199
BDBM516109 US11053226, Example 199
BDBM523708 US11136311, Compound 199
BDBM527406 US11186582, Example 199
BDBM528319 US11180494, Example 199
BDBM529792 US11203591, Example 199
BDBM533700 US11225469, Compound 199
BDBM534092 WO2022081807, Example 199
BDBM536592 US11242361, Compound 199
BDBM541596 US11267811, Example 199
BDBM541993 US11267824, Example 199
BDBM544715 US11286268, Compound 199
BDBM546926 US11292791, Example 199
BDBM552565 WO2022098970, Example 199
BDBM555523 US11344549, Example 199
BDBM561370 US11390610, Example 199
BDBM582525 US11524940, Compound 199
BDBM583076 US11548892, Compound 199
BDBM584451 US11524968, Example 199
BDBM587950 US11535621, Example 199
BDBM592504 US11572368, Compound 199
BDBM596093 US11591336, Compound 199
BDBM603226 US11649255, Example 199
BDBM607261 US11685745, Example 199
BDBM612937 US11725000, Compound 199
BDBM615408 US20230271949, Example 199
BDBM623181 US11780845, Example 199
BDBM625153 US20230322747, Compound 199
BDBM629901 US20230340011, Example 199.
BDBM631616 US20230348424, Example 199
BDBM633785 US11807646, Example 199
BDBM637284 US20230382904, Compound 199
BDBM638604 US11834467, Example 199
BDBM641305 US11845723, Example 199
BDBM655430 US11912703, Example 199
BDBM659550 US20240092770, Compound 199
BDBM665515 US20240116910, Compound 199
BDBM668935 US11964953, Example 199
BDBM669212 US11964973, Example 199
BDBM670255 US11970474, Example 199
BDBM682453 US20240207300, Compound 199
BDBM686754 US20240246937, Example 199
BDBM688085 US20240247015, Example 199
BDBM695033 US20240294551, Example 199
BDBM697417 US20240316047, Example 199
BDBM700093 US20240335442, Compound 199
BDBM701803 US12128028, Example 199
BDBM702448 US20240360148, Example 199
BDBM703252 US20240368104, Example 199
BDBM706323 US20240383893, Compound 199
BDBM716300 US20250032489, Compound 199
BDBM718344 US20250042889, Example 199
BDBM723625 US20250064789, Compound 199
BDBM725993 US20250074911, Example 199
BDBM730077 US12263171, Example 199
BDBM734655 US20250129067, Compound 199
BDBM735181 US20250129078, Compound 199
BDBM735612 US20250129103, Compound 199
BDBM735771 US20250129104, Compound 199
BDBM740104 US20250154134, Compound 199
BDBM740572 US20250154139, Compound 199
BDBM747029 US20250179047, Example 199
BDBM747149 US20250179065, Compound 199
BDBM749146 US20250188079, Compound 199
BDBM749577 US12331033, Example 199
BDBM750547 US20250195475, Example 199
BDBM751933 US20250197382, Compound 199
BDBM753202 US12338220, Example 199
BDBM755720 US20250214942, Example 199
BDBM756666 US20250215013, Example 199
BDBM756916 US20250221979, Example 199
BDBM759385 US12365696, Compound 199
BDBM759607 US20250236608, Example 199
BDBM761208 US20250243180, Compound 199
BDBM765570 US12391697, Example 199
US10029993, Example 199 BDBM280320
US10065950, Example 199 BDBM272357
US10112929, Example 199 BDBM295472
US10112941, Example 199 BDBM297092
US10130619, Example 199 BDBM300424
US10221177, Compound 199 BDBM361832
US10227329, Compound 199 BDBM367787
US10273259, Example 199 BDBM382490
US10323022, Example 199 BDBM398722
US10383880, Example 199 BDBM410989
US10435369, Example 199 BDBM414312
US10457654, Example 199 BDBM417339
US10457703, Example 199 BDBM419537
US10544143, Example 199 BDBM427766
US10562878, Compound 199 BDBM433799
US10570121, Example 199 BDBM435693
US10570167, Cpd. # 199 BDBM435867
US10597366, Compound 199 BDBM437928
US10604489, Compound 199 BDBM439009
US10604514, Compound 199 BDBM439284
US10660877, Example 199 BDBM443615
US10844044, Example 199 BDBM473257
US10899735, No. 199 BDBM479740
US10981917, Example 199 BDBM493498
US11028090, Example 199 BDBM502311
US11034715, Cpd. # 199 BDBM504447
US11045457, Example 199 BDBM506598
US11136296, Example 199 BDBM523468
US11149018, Example 199 BDBM520918
US11174245, # I-199 BDBM525521
US11254668, Example 199 BDBM538858
US11261186, Example 199 BDBM540272
US11377438, Example 199 BDBM560159
US11407740, Compound 199 BDBM563277
US11420970, Example 199 BDBM567997
US11420973, Example 199 BDBM568321
US11433053, Example 199 BDBM570305
US11458138, Example 199 BDBM574370
US11534441, Compound 199 BDBM587489
US11559538, Example 199 BDBM589952
US11584747, Example 199 BDBM594399
US11654147, Compound 199 BDBM603762
US11667652, Example 199 BDBM605405
US11685734, Example 199 BDBM606911
US11697648, Example 199 BDBM608630
US11773078, Example 199 BDBM621447
US11814367, Compound 199 BDBM634750
US11834453, Example 199 BDBM638096
US11912686, Compound 199 BDBM654254
US11999676, Compound 199 BDBM679336
US12319655, Example 199 BDBM745719
US12351572, Example 199 BDBM756383
US12384753, Example 199 BDBM763176
US20230312550, Example 199 BDBM622239
US20230339981, Example 199 BDBM629511
US20230348426, Example 199 BDBM631929
US20230348450, Example 199 BDBM632814
US20230357253, Compound 199 BDBM634299
US20230365546, Compound 199 BDBM636416
US20240002391, Compound 199 BDBM643387
US20240025884, Example 199 BDBM646988
US20240025919, Compound 199 BDBM647962
US20240043427, Example 199 BDBM650113
US20240092758, Example 199 BDBM659082
US20240101572, Example 199 BDBM661590
US20240116877, Example 199 BDBM664928
US20240116946, Example 199 BDBM666166
US20240132480, Example 199 BDBM669797
US20240140931, Compound 199 BDBM670587
US20240174662, Example 199 BDBM677535
US20240199605, Example 199 BDBM681640
US20240199649, Compound 199 BDBM681909
US20240218021, Example 199 BDBM684206
US20240262804, Example 199 BDBM689725
US20240287079, Example 199 BDBM694028
US20250026748, Compound 199 BDBM715035
US20250034135, Compound 199 BDBM716761
US20250059174, Example 199 BDBM721936
US20250059220, Compound 199 BDBM723086
US20250066350, Example 199 BDBM724374
US20250084074, Example 199 BDBM726885
US20250122174, Example 199 BDBM730617
US20250122183, Example 199 BDBM730986
US20250127903, Compound 199 BDBM733901
US20250145606, Example 199 BDBM738640
US20250170122, Compound 199 BDBM744275
US8501732, I-199 BDBM100639
US8536192, I-199 BDBM102410
US8633183, D-199 BDBM115815
US9359338, Exe. 199 BDBM235589
US9428478, TG6-199 BDBM244076
US9546153, ex. 199 BDBM209852
US9617282, Example 199 BDBM317424
US9745291, Compound 199 BDBM337153
US9777008, Compound 199 BDBM343905
US9790221, Compound 199 BDBM347993
US9815846, Compound 199 BDBM356199
US9862730, Example 199 BDBM364740
US9873693, Compound 199 BDBM366276
US9884814, Compound 199 BDBM275597
US9926281, Compound 199 BDBM379675
US9969687, Compound 199 BDBM393534
WO2022064009, Compound 199 BDBM530410
WO2022091056, Example 199 BDBM548208
CHEMBL376408 4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene)sulfonyl]benzamide US11760752, Compound ABT-737 BDBM21447 ABT-737 US9125913, ABT-737 N-Benylpiperazine derivative, 2
BDBM324993 US10189841, Compound I-199 1-(4-((2-(2- US10399980, Compound I-199
US10512632, Example 199 BDBM279168 US10618913, Example S199 5-(2-ethoxypyridin-3-yl)-3-(fluoromethyl)-1-isopropyl-N-((1-methyl-1H-pyrazol-4-yl)methyl)-1H-pyrazolo[4,3-b]pyridin-7-amine US10806718, Example 199 US10766893, Example S199 US11491140, Example 199 US11026923, Example 199 US11634416, Example 199 US10034861, Example 199
BDBM146150 US8957068, 199 US8957068, 200
BDBM188933 US9169260, 199 US9169260, 200
BDBM244781 US9550763, Compound I-199
BDBM306986 US10150728, Example I-199
BDBM323939 US10189809, Compound I-199
BDBM330647 US9725442, Compound I-199
BDBM332910 US10196390, Compound I-199
BDBM346634 US10202379, Reference Example 199
BDBM351104 US9796700, Compound I-199
BDBM369660 US10233156, Example I-199
BDBM398470 US10323018, Compound I-199
BDBM441275 US10640495, Example I-199
BDBM455181 US10730874, Compound I-199
BDBM463722 US10781204, Compound I-199
BDBM464867 US10793563, Compound I-199
BDBM465549 US10793568, Compound I-199
BDBM482132 US10913753, Compound I-199
BDBM513409 US11091472, Compound S-199
BDBM526855 US11186577, Cmpd. No. 199
BDBM557543 US11352356, Compound I-199
BDBM566830 US11420958, Ex. No. 199
BDBM582190 US11518764, Compound I-199
BDBM606555 US11685732, Compound I-199
BDBM608051 US11691963, Example I-199
BDBM640645 US20230399319, Example 2-199
BDBM678350 US20240174690, Example II-199
BDBM728585 US20250092056, Compound I-199
BDBM734962 US20250129069, Compound I-199
BDBM741395 US20250162989, Compound I-199
BDBM744599 US20250170126, Compound I-199
CHEMBL4632685 US11926614, Example 199 BDBM50541708
US10144742, Compound I-199 BDBM306037
US10233188, Example 199 BDBM467207 BDBM370312
US10774071, Example B-199 BDBM461732
US10919885, Compound No. 199 BDBM483050
US11198695, Example I-199 BDBM528988
US11198695, Example II-199 BDBM529263
US11214565, Example D-199 BDBM532940
US11339144, Compound I-199 BDBM554750
US11555012, Compound I-199 BDBM589458
US11691962, Compound 1-199 BDBM607801
US11753403, Compound I-199 BDBM617105
US12331046, Compound I-199 BDBM750069
US20230390274, Compound A-199 BDBM638862
US20240294545, Compound A-199 BDBM694783
US20250090540, Example I-199 BDBM727338
US8653100, 204 BDBM141305 US8653100, 199
US9260425, 201 US9260425, 199 BDBM206453
US9266883, 199 US9266883, 197 BDBM209357
US9763922, Example 199 CHEMBL3910675 BDBM50200398
US9957235, 2-199-1 BDBM390570
US9957235, 2-199-2 BDBM390571
WO2022090481, Example I-199 BDBM547978
US10266491, Example 199 US11053197, Example 199 BDBM377506 US10676434, Example 199 4-(3-(1-acryloylpyrrolidin-2- yl)phenyl)-3-fluoro-9H- carbazole-1-carboxamide
2-Methyl-3-((S)-1-pyrrolidin-2-ylmethoxy)-pyridine CHEMBL127071 BDBM50056147 ABT-089
3-Methyl-5-(1-methyl-pyrrolidin-2-yl)-isoxazole ABT-418 BDBM50171341 CHEMBL188981
BDBM130905 US8829199, 199 US10689705, Compound 48
US10442772, Example 2-199-1 BDBM415850
US10442772, Example 2-199-2 BDBM415851
US11866416, Compound SN-I-199 BDBM643887
US11390584, Example 199 US11066365, Example 199 BDBM447660 US10689345, Example 199 (3aR,6aR)-5-cyano-N-(4- cyano-2,5-difluorophenyl) hexahydropyrrolo[3,4-b] pyrrole-1(2H)-carboxamide
BDBM403936 US10017468, Compound 199 US11072582, Compound 199 US10781171, Compound 199 (2S,5R)-5-(2-chlorophenyl)-1-(2',4'-dichloro-[1,1'-biphenyl]-4-carbonyl)pyrrolidine-2-carboxylic acid
US11130759, Cpd. No. 199 US11046691, Compound 199 US11084798, Cpd No 199 methyl 1-(7-chloro-2-oxo-1-phenyl-1,2- dihydroquinazolin-4-yl)azetidine-3- carboxylate BDBM507796
US10604504, Example 95 US9688629, 154 US9688629, 153 US9920031, Example 199 US11623921, Example 95 US9802915, Example 199 BDBM164713
BDBM240484 US9409866, 199 US9409866, 240 US9409866, 239
BDBM341964 US9771320, Example 198 US9771320, Example 199
BDBM427762 US10544143, Example 199 US10544143, Example 195
BDBM50428079 US9303017, 25, YL-1-199 CHEMBL2323569
BDBM509164 US11072585, Example 61 Compound 1-199
BDBM563885 Roche-Dataset for PDE10A, Compound 199
BDBM596507 US11596639, Example 202 US11596639, Example 199
BDBM625565 US20230322789, Example 166 US20230322789, Compound 199
BDBM631865 US20230348426, Example 199 US20230348426, Example 135
BDBM637283 US20230382904, Compound 199 US20230382904, Compound 198
BDBM710560 US12187701, Compound FMF-03-199-1
BDBM712446 US12187701, Compound FMF-04-199-1
BDBM99421 US8497281, 199 US9663470, 132 US9120769, 132
US10059705, II-200 US10059705, II-199 BDBM270804
US10294229, Example 199 BDBM388050 US10294229, Example 204
US10323022, Example 199 BDBM398719 US10323022, Example 196
US11254668, Example 199 BDBM538857 US11254668, Example 198
US11584747, Example 199 BDBM594398 US11584747, Example 198
US11912703, Example 163 US11912703, Example 199 BDBM655358
US11999676, Compound 199 US11999676, Compound 198 BDBM679335
US12187701, Compound FMF-03-199-2 BDBM710561
US20240132480, Example 199 US20240132480, Example 168 BDBM669767
US20240336593, Example 155 US20250206717, Example 199 BDBM700392
US20250025443, Compound 199 BDBM714082 US20250025443, Example 116
US20250025443, Example 199 US20250025443, Compound 325 BDBM714165
US9303033, R27, Table 37A, Compound 199 BDBM219525
US9828339, Example 199 (S)-(1-methyl- BDBM360294
5-((S)-1-Azetidin-2-ylmethoxy)-2-chloro-pyridine A-98593 CHEMBL439766 BDBM50062639 ABT-594
N-({5-[5-(difluoromethyl)-1,3,4-oxadiazol-2- yl]-1,3-thiazol-2-yl}methyl)-N-(pyridin-3- yl)propanamide US20230381148, Compound I-199 US11578066, Compound I-199 US20240269137, Compound I-199 BDBM593507
US10738052, Example 199 BDBM388869 US11261191, Example 199 N-[2-(Dimethylamino)-1-methyl-2-oxoethyl]-2-fluoro-4-[3-(1-quinolin-6-ylcyclopropyl)imidazo[1,2-a]pyrimidin-6-yl]benzamide US9944645, 199
BDBM107485 US8575157, 199 US8598163, 69 US8592410, Comparator 11
BDBM195520 US9212153, 246,Ex. 199 US10336717, Compound 245
BDBM415099 Intermediate 1-2-30 US10428044, Example 199
BDBM420232 US10485800, Cmpd ID GV US10485800, Example 199
BDBM680979 US12012467, Example 199 US12012467, Compound DI-416
US11440913, Example 9-2 BDBM570943 US11440913, Example 199
US9212153, 244,Ex. 199 US10336717, Compound 244 BDBM195181
US9212153, 245,Ex. 199 US10336717, Compound 246 BDBM195519
WO2008054702, Example 199 BDBM721482 US12227517, Example cpd. C
med.21724, Compound 185 ABT-378 A-157378-0 BDBM50180655 Lopinavir CHEBI:31781 A-157378.0 Kaletra
1-(4-{[7-(6-methylpyridin-3-yl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]amino}piperidin-1-yl)prop-2-en-1-one US11111242, Example 199 US20250134869, Example 199 BDBM316704 US9617258, Example 199
BDBM282997 US9884868, Example 199' 1-(tert-butyl)-3-((6-(1-(2,2-difluoroethyl)-4-(4- fluorophenyl)-1H-imidazol-5-yl)imidazo[1,2- b]pyridazin-3-yl)methyl)urea US11352360, Example 199' US10287295, Example 199'
2-(N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(5-oxo-4,5-dihydro- BDBM477417 US10889555, Example 199 US11634395, Example 199
5-Chloro-N-[[1-(4-fluoro-3-methyl-phenyl)triazol-4-yl]methyl]-4- US10071988, Example 199 US10233173, Example 199 BDBM276261
BDBM510339 US11439633, Example 199 US11077100, Example 199 (5S,8S)-5-fluoro-8- hydroxy-N-(2- (trifluoromethyl) benzyl)-5,6,7,8- tetrahydroquinoline- 5-carboxamide
US11655217, Example 199 1-(4-(2-morpholino- 3-(trifluoromethyl)- benzyl)piperazine-1- carbonyl)-1H- pyrazole-3- carboxamide BDBM483716 US10927105, Ex 199
(R)-1-((7-cyano-2- (3'-(3-(((1-hydroxy- cyclopropyl)methyl- amino)methyl)-1,7- naphthyridin-8- ylamino)-2,2'- dimethylbiphenyl- 3-yl)benzo[d]oxazol- US10800768, Example 199 US10308644, Example 199 US11339149, Example 199 BDBM395587
BDBM193295 US9670204, 199 N-(2-ethyl-6-(1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl)imidazo[1,2-a]pyridin-3-yl)-3-(4-fluorophenyl)-N-methyl-1,2,4-thiadiazol-5-amine US10526329, Compound 199 US11072611, Compound 199
US11498926, Example 199 US9624241, Example 199 US10464947, Example 199 BDBM318671 tert-butyl (2-{[(4S)-7-(3,5- dimethylisoxazol-4-yl)-4-pyridin-2-yl- 4,5-dihydroimidazo[1,5,4- de][1,4]benzoxazin-2- yl]amino}ethyl)carbamate
US12065446, Example 199 N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(2-methyl-4-(pyridin-3- yloxy)phenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide BDBM485365 US10934310, Ex # 199 US11319329, Ex # 199
Tiagabine Abbott-70569 NO-05-0328 Abbott-70569.1 ABT-569 Gabitril TIAGABINE HYDROCHLORIDE BDBM50368628 NNC-05-0328
BDBM104371 US8575186, 134/183/184 US8575186, 200 US8575186, 199
BDBM107242 US8598345, 199 US8598345, Table 1-28/2-3
BDBM522641 US11161848, Compound I-199 1-(4-((2-(2-
BDBM694780 US20240294545, Compound A-199 US20240294545, Compound A-198
US8575186, 127/199/200 US8575186, 215 US8575186, 216 BDBM104364
US8703768, 199 BDBM120599 Roche-Dataset for PDE10A, Compound 696
BDBM379316 6-((4-(2-ethylhydrazinyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-3,4-dihydroquinolin-2(1H)-one US10266549, Example 199 US10774092, Example 199
US10131667, Example 199 3-[3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-2,3,4,7-tetrahydro-1H-pyrazolo[4',3':5,6]pyrido[4,3-d]pyrimidin-1-yl]-2-fluoro-N-isopropylbenzamide US11053246, Example 199 BDBM301383 US9611267, Example 199
US10815215, Example 199 US11130745, Example 199 BDBM470539 US11713304, Example 199 2-[(1S)-1-cyclohexylethoxy]-4-(3-ethyl-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-5-fluoro-N-[3-(methanesulfonyl)phenyl]benzamide
BDBM488821 US10961200, Compound 199 2-(4-(4- (hydroxymethyl)benzyl)- 3-phenyl-1H- pyrazol-1-yl)thiazole- 4-carboxylic acid US11247971, Cmpd ID 199
US10336775, Example 199 1-(4-Bromo-3-methoxyphenyl)-4-(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethyl)piperazine US11046712, No 199 BDBM408275
US10858342, Compound C-ABT BDBM473907 3-(6-Chloro-pyridin-3-yl)- 6,6-dimethyl-3,5,6,7- tetrahydro-benzoimidazol-4- one
4-imidazo[1,2- a]pyridin-3-yl- 7-[(5-morpholino-2- pyridyl)-amino]-2,3- dihydropyrrolo [3,4-c]pyridin-1- one US11078201, Compound I-199 US11021481, Compound I-198 BDBM500539 US11021481, Compound I-199 US11548890, Compound I-199
BDBM480981 US10906888, Example 200 US10906888, Example 198 US10906888, Example 199
BDBM322829 US10647720, Ex. # 199 4-((4-(2-aminoethoxy)phenyl)amino)-2- (azepan-1-yl)pyrimido[4,5-d]pyridazin- 5(6H)-one US10183944, Example 199
US10093640, Example 199 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-N-((2-(3-cyclohexylureido)ethyl)sulfonyl)-1H-indole-2-carboxamide US10844032, Example 199 BDBM286510
BDBM420695 US10479784, Compound IA-199 5-[3-amino-6-(4-isopropylsulfonylphenyl)pyrazin-2-yl]-N-(3-piperidyl)-1,3,4-oxadiazol-2-amine US10961232, Compound IA-199
US10544130, Example 199 US10221163, Example 199 BDBM361042 N1-(2-aminoethyl)-4-(1H-benzo[d]imidazol-4-yl)-3-(2H-tetrazol-5-yl)benzene-1,2-disulfonamide
5-(2,3-dichlorophenyl)-1,3,4-oxadiazol-2-ol US11634391, Compound 199 BDBM600948
US11124504, Cpd. No. 207 US10676469, Compound 207 BDBM450905 US10676469, Compound 199
US11020380, Example 199 2-Benzyl-4-(1,5-dimethyl-6-oxo-1,6-dihydro-pyridin-3- yl)-2H-pyrazole-3-carboxylic acid ethyl ester BDBM437465 US10617680, Example 199
CHEMBL219182 methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'ylmethyl)benzamide BDBM50200050 ABT-670
BDBM373932 US10246453, Example 199 US10815229, Example 199 (S)-5-chloro-4-((1-(4-(dimethylamino)benzyl)pyrrolidin-3-yl)(methyl)amino)-2-fluoro-N-(thiazol-4-yl)benzenesulfonamide
BDBM484400 (S)-4-(3-(1-acryloylpiperidin- 2-yl)-8-(trifluoromethyl) imidazo[1,5-a]pyrazin-1-yl)- N-(pyridin-2-yl)benzamide US11554118, Compound 199 US10933063, Compound 199
US11718603, Example 199 BDBM498374 US11014911, Example 199 (1S,3R)-3-(3-{[(3- methylimidazo[2,1- b][1,3]thiazol-6- yl)acetyl]amino}-1H-pyrazol-5- yl)cyclopentyl propylcarbamate
(1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-trifluorophenyl)cyclohex-3-en-1-aminium; 2,2,2-trifluoroacetate ABT-341 analogue 22 BDBM12655
CHEMBL29982 BDBM17325 ABT-839 (2S)-2-[(4-{[butyl(2-cyclohexylethyl)amino]methyl}-2-(2-methylphenyl)phenyl)formamido]-4-(methylsulfanyl)butanoic acid
2-(6-amino-5-benzylpyridazin-3-yl)phenol US10308614, Example 199 BDBM394596
BDBM291884 5-(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-N,N,6-trimethylpicolinamide US11207325, Example 199 US9580437, Example 199
N-(3-Methyloxetan-3-yl)-2-[3-methyl-2-oxo-6-[3- (trifluoromethyl)phenyl]imidazo[4,5-b]pyridin-1-yl]acetamide BDBM436864 US11207298, Example 199 US10617676, Example 199
(6r,10s)-11-{[3-chloro-2-(trifluoromethyl)pyridin-4-yl]carbonyl}-3-pyridin-2-yl-5,6,7,8,9,10-hexahydro-6,10-epimino[1,2,4]triazolo[4,3-a]azocine BDBM203324 US10053462, 199 US9540388, 199
1-{2-(1-Fluoro-cyclobutyl)-4-[4- (2-methoxy-phenyl)-piperidin-1- yl]-pyrido[3,4-d]pyrimidin-6-yl}- pyrrolidin-3-ol US10118902, Example 199 BDBM297696 US10584103, Example 199
US11492351, Example 4-199 BDBM579018 US11479551, Example 4-199 6-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin-6-yl)-1-methyl-1H- pyrazol-5-yl)-3-chloro-2-ethylbenzonitrile
(1S,6R)-3-{[(3-carbamoylphenyl)amino]methyl}-6-(2,4,5-trifluorophenyl)cyclohex-3-en-1-aminium; 2,2,2-trifluoroacetate BDBM12653 ABT-341 analogue 19
BDBM12652 ABT-341 analogue 14 (1S,6R)-3-(1,2,3,4-tetrahydroisoquinolin-2-ylmethyl)-6-(2,4,5-trifluorophenyl)cyclohex-3-en-1-aminium; 2,2,2-trifluoroacetate
US10112929, Example 199 US10112929, Example 173 US10112929, Example 198 US10112929, Example 172 BDBM295446
(S)-1-(1-(1H- benzo[d]imidazol-5- yl)-8,9-dihydro-7H- 6-oxa-2,9a- diazabenzo[cd]azulen- 4-yl)pyrrolidine-2- carboxamide US10065970, Compound 199 BDBM272894 US10435414, Compound 199
BDBM315018 (5-fluoro-2-(pyrimidin-2-yl)phenyl)((1S,4S,6R)-6-((5-(trifluoromethyl)pyrazin-2-yl)amino)-2-azabicyclo[2.2.1]heptan-2-yl)methanone US10183953, Example 199 US9611277, Example 199
US11111237, Example 199 US11725001, Example 199 BDBM518061 4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-8-[4-[2-fluoroethyl(methyl) amino]cyclohexoxy]-2,3-dihydro-1,4-benzoxazepin-5-one
US11370786, Example 199 US10344025, Example 199 1-(4-(6-(2-(3-(3,6-dihydro-2H-pyran- 4-yl)phenyl)acetamido)pyridazin-3- yl)butyl)-N-methyl-1H-1,2,3-triazole- 4-carboxamide BDBM404855
BDBM326993 US9662339, 199 4-{4-[(2R)-2,3-dihydro-1,4- benzodioxin-2- yl]benzyl}morpholine
BDBM396574 3-[5-Trifluoromethyl-2-(5-trifluoromethyl-furan-2-ylmethoxy)-phenoxy]- US9981909, Example 199
(R,E)-N-(1-(3-Cyclopropylacryloyl)piperidin-3-yl)-5-(2-methyl-4- phenoxyphenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide; BDBM467547 US10800792, Example 199 US10822348, Example 199
BDBM417582 US11001575, Example 199 2-(6-{5-chloro-2-[(oxan- 4-yl)amino]pyrimidin-4- yl}-1-oxo-2,3-dihydro- 1H-isoindol-2-yl)-N-(2- cyclohexylethyl)-N- methylacetamide US10457669, Example 199
N-methyl-N-[3-({[2-({3-[(4- methylpiperazin-1- yl)carbonyl]phenyl}amino)-5- (trifluoromethyl)pyrimidin-4- yl]amino}methyl)pyridin-2- yl]methanesulfonamide (199), trifluoroacetic acid salt BDBM418708 US10450297, Example 199
4-[3-(cyclopropylmethoxy)-6- methylsulfonylpyridin-2-yl]-2- methylisoquinolin-1-one BDBM485998 US10941160, Example 199
BDBM757560 US12357603, Example 199 N-([1,1'-biphenyl]-2-ylsulfonyl)-6-(dimethylamino)-5-fluorobenzofuran-2-carboxamide
US11352340, Example 199 BDBM557149 2'-(4,5- Dimethyl-1H- imidazol-2-yl)- 5-[(3- methoxyazetidin- 1-
(S)-5-(4-((4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)amino)-1,3,5-triazin-2-yl)-2-((6-oxopiperidin-3-yl)oxy)benzonitrile BDBM277892 US10040781, Example 199 US10253019, Example 199 US10040781, Example 114
6-[(2-{4-[5-Chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-5-methoxy-2-oxopyridin-1(2H)-yl}butanoyl)amino]quinolin-2-aminium formate (Racemate) BDBM413806 US11180471, Example 199 US10421742, Example 199
(2R)-9-ethynyl-2-methyl-3,5-dihydro-2H-1,5-benzoxazepin-4-one US10206931, Example 199 BDBM349391
2-(4-((2-(Cyclopentyloxy)-6-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)ethanol BDBM562627 US11401286, Example 199
3-{(1R)-1-[(6,7-dimethoxy-2-methylquinazolin-4-yl)amino]ethyl}benzamide US20240083857, Example 199 BDBM657520
4-(1H-indazol-5-yl)-3-(2H- tetrazol-5-yl)pyridine-2 sulfonamide BDBM262347 US9708336, 199
4-[3-(cyclopropylmethoxy)-6- methylsulfonylpyridin-2-yl]-2- methylisoquinolin-1-one BDBM485998 BDBM285154 US10023592, Example 199
4-[4-(2,3-dihydro-1,4- benzodioxin-2- yl)benzyl]morpholine BDBM326922 US11957671, Compound 199 US9662339, 2
BDBM449218 N-[(4-tetrahydropyran-4- ylsulfonylphenyl)methyl] imidazo[1,2-a]pyrimidine-6- carboxamide US10696692, Example 199
BDBM645997 Step 1: 2-(5-hydroxy-1H-pyrazol-3-yl)isoindoline-1,3-dione US20240018157, Example 199
BDBM660813 N-(2-methylpyrimidin-5-yl)-6- (pyridin-4- ylmethoxy)isoquinolin-1- amine US20240101531, Example 199
US11279687, Compound 199 1-(pyridin-3-ylmethyl)-3-(4-{[3- (trifluoromethyl)benzene]sulfonyl} phenyl)urea BDBM543190
US9174982, 200 US10213433, Compound 198 US9174982, 198 US9174982, 199 BDBM189635 US20240043404, Example 198 US11369599, Compound 198
US9663460, Example 199 N-{2-[(3-aminobenzyl)sulfinyl]-5-methoxy-phenyl}-1-benzofuran-2-sulfonamide BDBM327392
2-(4-Pyridin-2-yl-piperazin-1-ylmethyl)-1H-benzoimidazole CHEMBL440687 ABT-724 BDBM50145075 2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole
3-(5-(1,3,4-oxadiazol-2-yl)pyridin-3-yl)-4-(trifluoromethoxy)phenyl octylcarbamate BDBM734223 US20250129027, Example 199
3-(pyridin-4-yl)-1-(2,8-diazaspiro[4.5]decan-8-yl)-2,6-naphthyridine BDBM678474 US20240174696, Compound 199
BDBM338764 US9751885, 199 N-cyclopentyl-3-(trans- 2-((1-cyclopropyl- piperidin-4-yl)amino)- cyclopropyl)benzamide dihydrochloride
BDBM378071 US10266526, Compound 199 N-(1-(1-(L-alanyl)piperidin-4-yl)ethyl)-2-hydroxyquinoline-4-carboxamide
BDBM383717 US10280149, Example 199 4-[[4-cyclobutyl-2-(6-methoxynaphthalene-2-carbonyl)piperazin-1-yl]methyl]benzonitrile
BDBM436027 5-[2-Methyl-3-(1,2,4-oxadiazol-5-yl)phenyl]-1,3-dihydrobenzimidazol-2-one; US10611730, Example 199
BDBM612511 US11724992, Example 199 N'-((4-cyano-2,6- diisopropylphenyl)carbamoyl)-3,5- bis(2-hydroxypropan-2- yl)benzenesulfonimidamide
BDBM691738 4-chlorobenzyl (4-(2-((6- methylpyridin-3- yl)amino)-2- oxoethyl)phenyl)carbamate US20240279215, Compound 199
US10106534, Example 199 BDBM293857 3-({[(4R)-7-{methyl[5-(propan-2-yl)pyridin-2-yl]amino}-3,4-
US11312712, Example 199 BDBM551087 3-(7-Chloro-1H-indazol-5-yl)-2-(trifluoromethyl)imidazo[4,5-b]pyridine;
(1R,3S,5R)-2-(2-(3- acetyl-5-(2-(2- methoxyethylamino) pyrimidin-5-yl)- 1H-indol-1- yl)acetyl)-N-(6- bromopyridin-2- yl)-2- azabicyclo[3.1.0] hexane-3- carboxamide US10287301, Compound 199 US10822352, Comp No. 199 BDBM386269
US11021463, Example 106 US10266515, Example 107 US10023557, Example 107 US10023557, Example 106 N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((5-chloro-2H-indazol-2- yl)methyl)isonicotinamide US10023557, Example 199 US9611252, Example 106 BDBM283454 US10308637, Example 199
(R)-N-(1-(4-chlorophenyl)-2,2,2- trifluoroethyl)-N-methylimidazo[1,2- a]pyrazine-6-sulfonamide BDBM732655 US20250115569, Example 199
3-cyano-2-fluoro-N-(3- (oxazol-5-yl)-1H-indazol-5- yl)benzamide US11427558, Example 199 BDBM569052
BDBM432500 N-(8-(4-aminobutanoyl)-8- azabicyclo[3.2.1]octan-3-yl)-5- cyclopropylisoxazole-3-carboxamide US10577363, Compound 199
BDBM556964 3-(3-(2-Phenylpyridin-4-yl)-1H-1,2,4-triazol-5-yl)pyrrolidine-1-carbonitrile US11352339, Example 199
BDBM579755 N-(4-((5-(4-bromophenyl)-1H- pyrazol-3-yl)amino)-3- methylphenyl)methanesulfon- amide US11485711, Compound 199
BDBM736714 N-[2-amino-5-(4-fluorophenyl)phenyl]-4-[(5-methyl-3-pyridyl)sulfonimidoyl]benzamide US20250136570, Compound 199
N-{cyano[4- (trifluoromethyl)phenyl]methyl}- 2-(dimethylamino)-6-oxo-1,6- dihydropyrimidine-4- carboxamide BDBM384979 US10285989, Example 199
US9556139, 199 sodium 6-chloro-7-(4- (4-chloro-2-(cyclopropyl- methoxy)phenethylcarbamoyl) phenoxy)chroman-4-carboxylate BDBM234896
US9855269, Compound 46 US9592235, Example 199 6-(3-methoxy- 1-piperidyl) pyrido[3,2-d] pyrimidin- 4-amine BDBM299406
CHEMBL326702 N-[3-(1H-imidazol-4-ylmethyl)-phenyl]ethanesulfonamide N-(3-((1H-imidazol-4-yl)methyl)phenyl)ethanesulfonamide ABT-866 BDBM50118705 Ethanesulfonic acid [3-(1H-imidazol-4-ylmethyl)-phenyl]-amide
(R/S)-2-[6-(4-Fluoro-3-methyl-phenyl)pyrrolo[3,2-b]pyridin-1-yl]- US10377753, Example 199 BDBM409308
2-cyclopropyl-6-oxo-N-(1-{4- [(trifluoromethyl)sulfanyl]phenyl} cyclopropyl)-1,6-dihydropyrimidine-4- carboxamide BDBM355108 US9815796, Example 199
3-Morpholin-4-ylpropyl 4-{[(4-bromo-2,5-dichlorothiophen-3-yl)sulfonyl]amino}-2-hydroxybenzoate trifluoroacetate US9718809, 199 BDBM267090
5-[3-(2-chloropyridin-3-yl)-1,2,4- oxadiazol-5-yl]-1- (cyclopropylmethyl)-1H-1,2,3- benzotriazole US11912693, Compound 199 BDBM654589
BDBM343006 4-(3',4'-difluoro-5-methoxy-2-methyl-4-biphenylyl)-N-3-isoxazolyl-7-quinazolinesulfonamide US9776995, Example 199
BDBM426259 5-[2-tert-Butyl-7-(6-oxa-2-azaspiro[3;3]heptan-2-yl)pyrazolo[1,5- US10513523, Example 199
BDBM585584 6-[3-(Difluoromethyl)-4-fluoro-phenyl]-3-methyl-1-(3- pyridylmethyl)pyrazolo[4,3-b]pyridine US11530210, Example 199
BDBM598561 N-(2-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyrimidin-4-yl)-1H-indazol-5-amine US11613531, Example 199
N-[2-methyl-8-(5- methylfuran-2- yl)imidazo[1,2-a]pyrazin-6- yl]cyclopropanecarboxamide BDBM612217 US11718622, Compound 199
US10407409, Example 199 BDBM413261 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(1-(methoxymethyl)cyclobutyl)nicotinamide
US9579320, Example 199 4-(4-(4H-1,2,4-triazol-4-ylphenylamino)-2-((1R,2S)-2-aminocyclohexylamino)pyrimidine-5-carboxamide BDBM290800
US9776991, Example 199 2-[4-(3-Dimethylamino-propionyl)-piperazin-1-ylmethyl]-thiazole-5-carboxylic acid 2,4-dichloro-benzylamide BDBM342829
(R)-4-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)benzonitrile 4-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-benzonitrile ABT-239 CHEMBL351231 BDBM50139391
4-(6-bromo-3-quinolylamino)- 2-{3-methoxy-4-[(1r,3r)-3- (dimethylamino)cyclobutoxy] phenylamino}pyrimidine BDBM744904 US20250171431, Compound 199
BDBM302632 2-(3-Chloro-4- fluorophenyl)-N5-(4- fluorophenyl)-6,7- dihydropyrazolo[1,5-a] pyrazine-3,5(4H)- dicarboxamide US9598423, Example 199
BDBM363956 US9855269, Compound 199 6-[3-fluoro-5-[(2-methylpyrrolidin-1-yl)methyl]phenyl]pyrido[3,2-d]pyrimidin-4-amine
BDBM411203 US10385022, Example 199 N-Carbamoylmethyl-N-[4-(2-fluoro-6-methoxy-phenyl)-pyridin-3-yl]-2,6-bis-trifluoromethyl-isonicotinamide
US10294212, No. 199 BDBM387615 N3-(3-Chloro-4- fluorophenyl)- 7-(3- (trifluoro- methyl)phenyl) furo[2,3-c] pyridine-2,3- diamine
US10696692, Example 21 Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4- (tetrahydro-pyran-4- sulfonyl)-benzylamide BDBM449043 US10696692, Example 199
US9656988, Example 199 (R)-3-(4-(1-cyanocyclopropyl)phenylamino)-5-(3-(3,3-dimethylureido)piperidin-1-yl)pyrazine-2-carboxamide BDBM309730
US9663513, 199 BDBM329586 Trans-4-(2-methyl-4- (((1S,2S)-2-(pyridin-2- yl)cyclopropyl)methoxy) pyrimidin-5- yl)cyclohexanol
1-(2-((1R,3S,5R)-3-((6-bromo-5-fluoro-3- methylpyridin-2-yl)carbamoyl)-5-methyl-2- azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)-5- (2-methylpyrimidin-5-yl)-1H-pyrazolo[3,4- c]pyridine-3-carboxamide US11084800, Cpd No. 199 BDBM511884 US11708351, Compound 199
BDBM315777 US10172859, Example 199 US11065253, Example 199 US9732094, Example 199 4-[5-(Difluoro- methoxy-thiazol-2- ylmethyl)-2-fluoro- phenyl]-7- morpholin-4-yl- quinazoline1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.85 (d, J = 3.2, 1H), 7.81 (d, J = 3.2, 1H),7.73-7.71 (m, 2H), 7.55-7.52 (m, 2H), 7.52-7.48 (m, 1H), 7.22-6.82 (m, 3H), 3.80-3.75(m, 4H), 3.48-3.42 (m, 4H)
(S)-3-methyl-5-(1-methylpyrrolidin-2-yl)isoxazole BDBM50035398 3-Methyl-5-((S)-1-methyl-pyrrolidin-2-yl)-isoxazole ABT-418 (S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidinium CHEMBL274525
CHEMBL729 ABT-378 BDBM578 LPV Aluviran Lopinavir (2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(2-(trifluoromethyl)benzyl)-2-azaspiro[3.3]heptan-2-yl)methanone BDBM630609 US11802111, Example 199
(3aR,6aR)-5-cyano-N-(4- cyano-2,5- difluorophenyl)hexahydro- pyrrolo[3,4-b]pyrrole- 1(2H)-carboxamide US10343992, Example 199 BDBM404547
(S)-4-(2-(5-fluoropyridin-2-yl)-4-(trifluoromethyl)phenyl)-N-(pyridazin-3-yl)chroman-7-sulfonamide US10239869, Example 199 BDBM371773
BDBM173996 US9688661, 2-(5-Chloro-2-ethylphenyl)-5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrrole-3-carboxamide (compd 199)
BDBM283550 N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((5-chloro-2H-indazol-2- yl)methyl)isonicotinamide US10023557, Example 199
BDBM328061 N-((cis)-4-(4-cyano-3- fluorophenoxy) cyclohexyl)-5-(4-(4- (trifluoromethyl) phenoxy)piperidine-1- carbonyl)picolinamide US9663496, Compound 199
BDBM380204 5-chloro-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)phenyl]-1-phenyl-1H- pyrazole-4-carboxamide US9926282, Example 199
BDBM416053 6-[(4- methoxycyclohexyl)carbonyl]- 8-(4-methoxypiperidin-1-yl)- 6,11-dihydro-5H-pyrido[2,3- b][1,5]benzodiazepine US10442819, Example 199
BDBM455611 N-[[6-(3-phenylpropanoyl)-6- azaspiro(25]octan-2yl]methyl]- 1,3-dihydropyrrolo[3,4- c]pyridine-2-carboxamide US10730889, Example 199
BDBM683242 4-(5-(3-amino-8-azadicyclo [3.2.1]octane-8-carbonyl)- 2-methylthiophene- 3-yl)-2-fluorobenzonitrile hydrochloride US20240216357, Example 199
N-((cis)-4-(4-cyano-3- fluorophenoxy)cyclohexyl)-5-(4-(4- (trifluoromethyl)phenoxy)piperidine-1- carbonyl)picolinamide US10377742, Compound 199 BDBM409173
N-(1,6-dimethyl-9H- xanthen-9-yl)-4-methyl-2- oxo-6-(trifluoromethyl)-1,2- dihydropyridine-3- carboxamide US11957687, Compound 199 BDBM667252
N-(trans-3-((5-(4-phenoxybenzoyl)-7H- pyrrolo[2,3-d]pyrimidin-4- yl)amino)cyclobutyl)acetamide US11020398, Compound I-199 BDBM499887
US10287286, Example 199 2-(dimethylamino)ethyl N-[5- (4-cyano-3-fluorophenyl)- [1,2,4]triazolo[1,5-a]pyridin- 7-yl]carbamate BDBM385796
US11434240, Compound I-224 US10781204, Compound I-153 US10781204, Compound I-143 BDBM463664 US10781204, Compound I-199 US10781204, Compound I-224
US20240025883, Example 199 BDBM646694 6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyrimidin-2-yl]-7- (difluoromethylsulfanyl)-1H- indole-3-sulfonamide
US20240376090, Compound 199 N-[3-(3,5-dimethylisoxazol-4-yl)-4-[[(2R)-2- piperidyl]methoxy]phenyl]-2-fluoro-2-methyl-propanamide BDBM704832
{[4-hydroxy-1-(8-methoxy-2- methylquinazolin-4-yl)piperidin-4- yl]methyl}(imino)methyl-lambda6-sulfanone US11780849, Compound 199 BDBM624662
US20240174647, Example 199 BDBM677278 N4-((1S,2R)-2-fluorocyclopropyl)-N2-(1-(2-(methylsulfonyl)ethyl)-1H-indazol-4-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine (Example 198) and N4-((1S,2S)-2-fluorocyclopropyl)-N2-(1-(2-(methylsulfonyl)ethyl)-1-indazol-4-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine (Example 199)
BDBM12654 ABT-341 analogue 17 3-{[trans-5-Amino-4-(2,4,5-trifluorophenyl)cyclohex-1-en-1-yl]methoxy}benzamide (1S,6R)-3-(3-carbamoylphenoxymethyl)-6-(2,4,5-trifluorophenyl)cyclohex-3-en-1-aminium; 2,2,2-trifluoroacetate
CB 7598 CHEMBL254328 (1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-7,13-dien-5-ol ABT Abiraterone US9487554, Abiraterone BDBM25458 US9611270, Example 5, abiraterone
(2S)-1-(benzofuran-2- ylsulfonyl)-N-[[2-[2- (trifluoromethyl)pyrimidin- 5-yl]-4- pyridyl]methyl]pyrrolidine- 2-carboxamide BDBM611306 US10626112, Example 199
5-[4′-Chloro-2-(difluoromethyl)[1,1′-biphenyl]-4-yl]-3,6-dihydro-2H-1,3,4-oxadiazin-2-one US11427553, Example 199 BDBM568736
BDBM331956 methyl 2-((2-(2-((5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl)amino)ethoxy)ethyl)amino)acetate US10189859, Compound 199
BDBM375004 US10251893, Cpd 199 2-(2'-fluoro-3-methyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
BDBM380995 US9890171, 199 US9890171, 200 8-(4,4-Difluoro-isochroman-7-yl)- 3,4-dihydro-1H-pyrano[4,3-c]pyridin- 4-ol, Enantiomer II
BDBM421156 N-(1-((3-(4-Aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-4- methylphenyl)sulfonyl)pyrrolidin-3-yl)acetamide US10479795, Example 199
BDBM487293 2-Amino-5-(1H-benzo[d][1,2,3]triazol-5-yl)-3-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one US10953012, Example 199
BDBM519947 1,1,1,3,3,3- Hexafluoropropan- 2-yl 4-(2,2- difluoro-2-(5- methoxypyrazin- 2-yl)-N- methylacetamido)-4- methylpiperidine-1- carboxylate US11142526, Example 199
BDBM580310 US11485745, Example 199 N-[[6-(3-phenylpropanoyl)-6- azaspiro[2.5]octan-2-yl]methyl]- 1,3-dihydropyrrolo[3,4- c]pyridine-2-carboxamide
BDBM725449 (S)-3-(4-(ethylsulfonamido)-3-(1-(4- fluorophenyl)ethoxy)phenyl)-5- (pyrazin-2-ylamino)-1H-pyrazole-4- carboxamide US20250074891, Compound 199
US10538497, Example 199 2-((4-(N-(3-bromo-4- fluorophenyl)-N'- hydroxycarbamimidoyl)-1,2,5- oxadiazol-3-yl)thio)-N-(N- methylsulfamoyl)acetamide BDBM430009
US11566003, Compound 199 (R)-2-(3-(8-amino-6-(4-methylpyridin-3-yl)isoquinolin-3-ylamino)-1H-pyrazol-1-yl)propanenitrile BDBM591107
US12065436, Compound 199 2-methyl-N-(6-(5-methyl-1,2,4- oxadiazol-3-yl)-2,3- dihydrobenzofuran-3-yl)-2H- tetrazole-5-carboxamide BDBM690810
US20240374606, Example 199 5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7-yl)-3-[4-(1-methylsulfonylcyclopropyl)anilino]pyrazine-2-carboxamide BDBM704646
trans-4-(2-fluorophenyl)-N-(3-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-amine US9656955, Example 199 BDBM308685
2-(azetidin-1-ylmethyl)-N-(2-chloro-5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)phenyl)quinoline-6-carboxamide US9701664, Example 199 BDBM610391
3-[2-Methyl-3-(trifluoromethyl)benzyl]-2,4-dioxo-1-[4-(4-oxoimidazolidin-1-yl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid BDBM337805 US9751843, 199
BDBM297983 US10118930, Example 199 3-(3-ethyl-1,2,4-oxadiazol-5-yl)-7-(piperidin-4-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one hydrochloride
BDBM322446 US10183938, Compound (R)-199 (R)-7-(methoxymethyl)-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[2.2.2]octan]-3'-yl)benzo[b]thiophene-2-carboxamide
BDBM333650 US9730937, Example 199 1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl]- 3-[1- p- tolyl-3- (trifluoromethyl)- 1H- pyrazol-5-yl]urea
BDBM351479 US9796704, Entry 199 N-(3,4-dichlorophenyl)-7-[({4-[4- (diethylamino)phenyl]-1,3-thiazol-2- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine
BDBM365947 N-(2-((4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-2,5-difluorobenzyl)amino)ethyl)acetamide US9872852, Example 199
BDBM462875 {(1R,2S,4R)-4-[(5-{[4-(cyclohexylmethyl)-2-thienyl]carbonyl}pyrimidin-4-yl)amino]- 2-hydroxycyclopentyl}methyl sulfamate US10780090, Compound I-199
BDBM613458 1-[4-(cyanomethyl)-3-fluoro-1- [[4-(triazol-2-yl)phenyl]methyl]- 4-piperidyl]-3- (cyclopropanecarbonylamino) pyrazole-4-carboxamide US11731943, Example 199
US10173991, Example 199 2-[6-(6- cyanopyridin-3- yl)-5-fluoro-1,3- benzothiazol- 2-yl]-N- [(cyclopropyl- carbamoyl) methyl]-2- methanesulfonyl- acetamide BDBM319156
US11174268, Example 199 4-((2-chloro-6-((2,2-dimethylazetidin-1-yl)methyl)benzyl)amino)-2,6-difluoro-N-(thiazol-4-yl)benzenesulfonamide formate BDBM526092
US11203600, Example 199 4-[4-fluoro-1-(3- isoquinolyl)piperidine- 4-carbonyl]-3,5- dihydro-2H- pyrido[3,4- f][1,4]oxazepine-9- carbonitrile BDBM530122
US20240262819, Example 199 BDBM690055 (S)-quinuclidin-3-yl((R)-6-(2-chloro-4-isopropoxyphenyl)-7-fluoro-2,2-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl) carbamate
(1r,4r)-4-(3-chloroanilino)-2′-[2-(pyridin-2-yl)ethyl]spiro[cyclohexane-1,1′-indene]-4-carboxylic acid US20240150293, Example 199 BDBM673064
(3-ethoxy-6-methylpyridin-2-yl)((2S*,3R*)-2-methyl-3-((5-(trifluoromethyl)pyrimidin-2-yl)amino)piperidin-1-yl)methanone BDBM314581 US9611251, 199
(3aR,6aR)-5-cyano-N-(4- cyano-2- fluorophenyl)hexahydro- pyrrolo[3,4-b]pyrrole- 1(2H)-carboxamide US10343992, Example 198 US10343992, Example 199 BDBM404546
1-N'-(4-fluorophenyl)-1-N- [4-[6-(3-hydroxyazetidin- 1-yl)-7- methoxyquinolin-4- yl]oxyphenyl]cyclopropane- 1,1-dicarboxamide BDBM588269 US11542259, Compound 199
3,5-dichloro-N-(2,8-dimethyl-4- oxo-3-((6- (trifluoromethyl)pyridin-2- yl)methyl)-3,4- dihydroquinazolin-5-yl)-4- hydroxybenzamide US20230278981, Example 199 BDBM616384
4-(4-{[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl]amino}-3,5-dimethyl-1H-pyrazol-1-yl)benzonitrile US11208400, Example 199 BDBM531566
6-{6-[2-(7-Methoxy-2,3-dihydro-benzo[1,4]dioxin-6-yl)-ethylamino]-pyrimidin-4-yl}- benzofuran-3-carboxylic acid US11839613, Example 199 BDBM640078
BDBM306556 US10144746, Compound 199 (1R,8S)-N-[(4-carbamimidoyl- 2,6-dimethyl-phenyl)methyl]- 12-(2,4-difluorophenyl)-15- oxatetracyclo[6.6.1.02,7.09,14] pentadeca-2,4,6,9,11,13- hexaene-4-carboxamide
BDBM315249 US10172814, Example 199 (−) 3-[3-({cyclopentyl[3-fluoro-4-(5-isopropoxypyridin-3-yl)phenyl]acetyl}amino)-2-methylphenyl]propanoic acid, Single Enantiomer
BDBM345654 Ethanesulfonic acid [2-(2-methoxy- phenyl)-6-(1-methyl-6-oxo-1,6- dihydro-pyridin-3-yl)-pyrimidin-4- yl]-amide US10202360, Example 199
BDBM416052 6-[(4- methoxycyclohexyl)carbonyl]- 8-(4-methoxypiperidin-1-yl)- 6,11-dihydro-5H-pyrido[2,3- b][1,5]benzodiazepine US10442819, Example 199 US10442819, Example 198
BDBM552024 US11312723, Example 199 (R*)-(3-amino- 4,5- dihydropyrano[3, 4-c]pyrazol- 2(7H)-yl)(8- methyl-1,2,3,4- tetrahydro- quinolin-4- yl)methanone
BDBM675730 3-((2S)-3-(8-(2-chloro-3-fluorophenylsulfonyl)-1-oxa-8-azaspiro[4.5]decan-3-ylamino)-2-hydroxypropoxy)-N-methylbenzenesulfonamide US11987588, Compound 199
N-(6-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-(4-(perfluoroethyl)-1H-imidazol-1-yl)picolinamide USRE48711, Example 199 BDBM517591
N-[6,7-Dichloro-1-[1-(2-hydroxy ethyl)triazol-4-yl]-3-(1H-pyrazol-4-yl)indol-4-yl]acetamide BDBM639730 US20230391786, Example 199
US10206907, Compound 199 BDBM349080 Cyclopropanecarboxylic acid {5-[4-(1-methyl-1H- [1,2,4]triazol-3-ylmethoxy)- phenyl]-[1,2,4]triazolo[1,5- a]pyridin-2-yl}-amide
US11034692, Compound 199 BDBM503918 (1R,2R)-N-(8-amino-6-(5-amino-4- methylpyridin-3-yl)-2,7-naphthyridin-3- yl)-2-cyanocyclopropane-1-carboxamide
US12071425, Compound 199 BDBM693289 1-phenyl-N-(2,3,6-trifluoro-4-((3-(2- (piperidin-3-ylmethyl)pyrimidin-4- yl)pyridin-2- yl)oxy)phenyl)methanesulfonamide
US12338237, Example 199 (S)-quinuclidin-3-yl (6'-(2-(methoxymethoxy)phenyl)-3',4'-dihydro-1'H-spiro[cyclopropane-1,2'-naphthalen]-1'-yl)carbamate BDBM753441
US20240368133, Compound A-199 1-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)phen- yl]-4-[(4-methoxy- 2-pyridyl)methyl]- piperazine BDBM703722
ABT-102 CHEMBL398338 N-[(1R)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea (R)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)urea BDBM50232114
5-(3-bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine 5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine ABT-702 CHEMBL66089 BDBM50094703
7-(3-fluorobenzenesulfonyl)-2-methyl-4-{6-oxa-9-azaspiro[4.5]decan-9-yl}-5H-pyrrolo[3,2-d]pyrimidin-6-amine BDBM271080 US10059713, Example 199
BDBM237383 US10052306, 199 rac-6-{2-[(3aR,5R,6aS)- 5-hydroxy-5-[(4- methoxyphenyl)methyl]- octahydrocyclopenta[c] pyrrol-2-yl]-1- hydroxyethyl}pyridin-3- ol
BDBM312453 2-[3-(3-Cyclopropyl-[1,2,4]thiadiazol-5-yl)-6,6-difluoro-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-cyclohex-1-enecarboxylic acid US9604977, Example 199
BDBM381366 US10272074, Example 199 4-chloro-3-methyl-1-(tetrahydro- 2H-thiopyran-4-yl)-N-(4- (trifluoromethyl)phenyl)-1H- pyrazolo[3,4-b]pyridine-5- carboxamide
BDBM602301 (R)-6-(1-ethylpiperidin-4-yl)-N-(1-(2- fluoro-3-(trifluoromethyl)phenyl)ethyl)-7- methoxypyrido[2,3-d]pyrimidin-4-amine US11648254, Compound 199
N-[2-(4-Cyano-3-fluoro-benzyl)-2H-[1,2,3]triazol-4-yl]-2-[3-methyl-4-(2,2,2-trifluoro-ethoxy)-phenyl]-acetamide US10246426, Example 199 BDBM372645
US10118930, Example 107 BDBM297882 3-(3-ethyl-1,2,4- oxadiazol-5-yl)-7- (piperidin-4- yl)pyrazolo[1,5- a]pyrimidin-5(4H)-one US10118930, Example 199
US10227299, Example 199 N-{4-[(6RS)-3-Anilino-6-{[(methylsulfonyl)amino]methyl}-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl]pyridin-2-yl}acetamide BDBM367511
US11634396, Compound 199 (S)-N-((S)-2-(dimethylamino)-3-(4-methyl-1H-indazol-5-yl)propyl)-3-(1-methylcyclopropyl)-3-(pyridin-3-yl)propanamide BDBM601260
US12011444, Example 199 5-{6-[2-(6,7-Difluoro-4-methoxy-2-methyl-indol-1-yl)-ethylamino]-pyrimidin-4-yl}-1,3- dihydro-indol-2-one BDBM679984
US20230286970, Compound 199 N-(5-(2-(4-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)benzyl)-2H-tetrazol-5-yl)pyridin-3-yl)morpholine-4-carboxamide BDBM618432
US20250163063, Example 199 2-(2-(((3R,4R)-1- (cyclopropylsulfonyl)-3- hydroxypiperidin-4-yl)amino)-5- fluoropyrrolo[2,1-f][1,2,4]triazin-7- yl)-5-fluorobenzonitrile BDBM742680
2-Amino-4′-((2-aminoethyl)sulfonyl)-3′-sulfamoyl-2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-3-carboxylic Acid US10227331, Example 199 BDBM368012
2-{4-[5-Amino-6-(2- amino-ethylamino)- pyrazin-2-yl]- benzylamino}-5- cyano-N-[(S)-1-(4- fluoro-phenyl)-ethyl]- nicotinamide BDBM282319 US10030016, Example 199
3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl)-N-(3-(3,4-difluorophenyl)- 2,2-difluoro-3-hydroxypropyl)-2-fluoro-6-methylbenzamide WO2022086828, Example 199 BDBM534463
4-((3R,4S)-4-amino-3- fluoropiperidin-1-yl)-N1-((R)- pyrrolidin-3-yl)-3-(2H-tetrazol- 5-yl)benzene-1,2-disulfonamide BDBM531067 US11207312, Example 199
5-((R)-2-(2-ethyl-5-fluoropyridin- 3-yl)pyrrolidin-1-yl)-N-((trans)-4- hydroxycyclohexyl)pyrazolo[1,5- a]pyrimidine-3-carboxamide US9796724, Example 199 BDBM354235
6-(3-fluorophenyl)-N-[3-({2- [(1S,4S)-2-oxa-5- azabicyclo[2.2.1]hept-5- yl]propanoyl}amino)-4- (trifluoromethoxy)phenyl] nicotinamide US10130633, Example 199 BDBM300629
BDBM299829 4-(4-{[(4- aminopyrimidin-5- yl)oxy]methyl} piperidin-1-yl)-N- cyclobutyl-6-[(2,2- difluoro- cyclopropyl) methoxy]-1,3,5- triazine-2- carboxamide US9593097, Example 199
BDBM333649 1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl]- 3-[1- (4- fluorophenyl)-3- (trifluoromethyl)- 1H- pyrazol-5-yl] urea US9730937, Example 199 US9730937, Example 198
BDBM402625 US10329294, Example 199 N-[3-(difluoromethyl)-1- (1-methylethyl)-1H- pyrazol-4-yl]-5-{[(1R,2S)- 2- hydroxycyclohexyl]amino} pyrazolo[1,5- a]pyrimidine-3- carboxamide
BDBM436424 US10590140, Example 199 8-(ethylamino)-1- methyl-4-(3-((3- (methylamino)-1- phenylpropoxy)methyl) phenyl)-1,2,3,4- tetrahydro-5H- pyrido[4,3- e][1,4]diazepin-5-one
BDBM466098 [3-(1-ethyl-8-oxo- spiro[6,7-dihydro-4H- pyrazolo[3,4-c]azepine- 5,4'-tetrahydropyran]-3- yl)-2,2-dimethyl-propyl] 3- methylsulfonylpropanoate US10793580, Example 199
BDBM644252 6-chloro-4-(4-(3-(ethyl(methyl)amino)benzyl)piperazin-1-yl)-1-methyl-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carbonitrile US11866430, Example 199
US10508104, Example 199 BDBM422292 5-[4-(6-fluoropyridin-3- yl)benzenesulfonyl]-6- hydroxy-1-[(1R)-2- methoxy-1- phenylethyl]-2-(3- methylbutyl)-1,4- dihydropyrimidin-4-one
US9556179, Compound 199 BDBM274625 2-chloro-N-(6-(2-(4- fluorophenyl)imidazo[1,2-a] pyridin-3-yl)imidazo[1,2-b] pyridazin-2-yl)-5- (trifluoromethyl) isonicotinamide
US9856220, Example 199 BDBM363825 (+)-2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro-isoquinoline-4-carboxylic acid (6,7-dihydro-5H-[1]pyrindin-5-yl)-amide
methyl 3-(5-(3-(5-(2-hydroxyethoxy)pyrazolo[1,5-a]pyridine-3-carboxamido)-4-methylphenyl)-2H-tetrazol-2-yl)azetidine-1-carboxylate BDBM690254 US20240262826, Compound 199
CHEMBL163 Norvir Ritonavir RTV 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate ABT-538 BDBM520
1,6-dimethyl-4- {4-methyl-4-[5- (propan-2-yl)- 1,3-benzoxazol-2- yl]piperidin-1- yl}-2-oxo-1,2- dihydroquinoline- 3-carboxamide US11998539, Example 199 BDBM678757
2-{5-[6-butyl-5- (2,6- dimethoxyphenyl)- 2,4- dihydroxypyridin- 3-yl]-1,3,4- oxadiazol-2-yl}-1- (3-fluoroazetidin-1- yl)ethan-1-one US10336739, Example 199 BDBM406601
5-(Dimethyl-1H-1,2,3-triazol-5-yl)-N-methyl-8-[(S)-oxan-4-yl(phenyl)methyl]-3,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2 US9725449, Example 199 BDBM331365
5-{2-acetamidoimidazo[1,2-b] pyridazin-6-yl}-N-[(1R)- 1-[2-fluoro-5-(trifluoromethoxy) phenyl](2,2,2-deutero)ethyl]- 2-methylpyridine- 3-carboxamide BDBM571132 US11440913, Example 199
BDBM275305 1-[(3R,4S)-1-ethyl-4- phenylpyrrolidin-3-yl]-3-[1- (2-methylpyridin-4-yl)-1H- pyrazolo[3,4-c]pyridin-5- yl]urea US9884048, Example 199
BDBM320794 (S)- or (R)-6-(Dimethylamino)-1-(1-(2- fluoro-4-(trifluoromethyl)phenyl)propyl)-3- (fluoromethyl)-1H-pyrazolo[3,4- d]pyrimidin-4(5H)-one US10174037, Example 199
BDBM406916 4-({2-[6-(difluoromethyl)pyridin-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)-N-[(1S,2S)-2-hydroxycyclopentyl]pyridine-3-carboxamide US10336761, Example 199
BDBM423013 US10508109, Example 199 3-(4-chloro-2-(7-(4- (ethylsulfonyl)piperazin-1- yl)imidazo[1,2-a]pyridine-2-yl)- 5-methoxyphenoxy)-N,N- dimethylpropan-1-amine
BDBM438846 US10604489, Compound 11 3-((1R,5S,9r)-3-(bicyclo[3.1.0]hexan-3-yl)-9-methoxy-3-azabicyclo[3.3.1]nonan-9-yl)benzamide hydrochloride US11180455, Compound 199
BDBM464317 US10787450, Example 199 3-(5-(1H-pyrazol-4- yl)pyridin-2-yl)-8-(2- hydroxy-2- methylpropanoyl)-1- (3-methoxybenzyl)- 1,3,8- triazaspiro[4.5]decan- 2-one
BDBM728151 (Z)-1-acetyl-2-((5- (1-methyl-1H-pyr- azol-4-yl)-6- (morpholine-4- carbonyl)quinolin- 2-yl)methylene)- indolin-3-one US20250091994, Example 199
BDBM758538 2'-chloro-5'-methoxy-6-methyl-N-(5-(5- methylpicolinoyl)-5,6-dihydro-4H- pyrrolo[3,4-d]thiazol-2-yl)-[4,4'- bipyridine]-3-carboxamide US20250230171, Compound 199
N-[1-[5-(2,6-difluorophenyl)- 11,11-dimethyl-3,4- diazatricyclo[6.2.1.02,7]undeca- 2,4,6-trien-1-yl]ethyl]-N-ethyl- 2,5-dimethyl-oxazole-4- carboxamide BDBM383484 US10280144, Compound 199
US10544106, Compound C197 BDBM426740 4-(8-(1-acryloylpyrrolidin-3-yl)-4-amino- imidazo[1,5-a][1,3,5]triazin-6-yl)-N- (pyridin-2-yl)benzamide US11208388, Example 199
US10988478, Example 199 BDBM494151 N-(6-(6,6- difluoro-3- azabicyclo[3.2.0] heptan-3-yl)-2,2- dimethyl-2,3- dihydrobenzo- furan-5- yl)pyrazolo[1,5- a]pyrimidine-3- carboxamide
US11618753, Example 199 BDBM599061 5-[4-amino-5- (trifluoromethyl) pyrrolo[2,1- f][1,2,4]triazin-7- yl]-N-(1- cyclopentyl-4- fluoropyrrolidin-3- yl)-2- methoxypyridine-3- carboxamide
US12071425, Compound 198 BDBM693288 US12071425, Compound 199 1-phenyl-N-(2,3,6-trifluoro-4-((3-(2- (piperidin-3-ylmethyl)pyrimidin-4- yl)pyridin-2- yl)oxy)phenyl)methanesulfonamide
cyclopropyl(3-(2-(1-methyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone BDBM702845 US20240360157, Example 199
2-cyano-N-{2-[(4-{N-[(7S)-4- fluorobicyclo[4.2.0]octa-1,3,5- trien-7-yl]-N'- hydroxycarbamimidoyl}-1,2,5- oxadiazol-3- yl)sulfanyl]ethyl}acetamide BDBM494803 US10988487, Example 199
6-(4-Methoxybenzyl)-9-((methyl((tetrahydro-2H-pyran-4-yl)methyl)amino)methyl)thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one BDBM289710 US10092575, Example 199
7-[[5-(4-hydroxy-1- piperidyl)-2- pyripyl]amino]-4- imidazo[1,2- b]pyridazin-3- yl-2,3-dihydropyrrolo [3,4-c]pyridin-1-one US11021481, Compound I-199 BDBM500540
BDBM227938 8-({[2-(Dimethylamino)ethyl](ethyl)amino}methyl)-4-[(2-fluoro-5-hydroxy-4-methylphenyl)amino]-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one US10047096, 199
BDBM292543 US10100058, Example 199 N-((S)-2-(diethylamino)propyl)-2-(((R)-1-hydroxypropan-2-yl)amino)-6-(5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl)isonicotinamide
BDBM609239 7-(5-(5-((1s,3s)-3-hydroxy-3-methylcyclobutyl)-1,3,4-thiadiazol-2-yl)-4-(isopropylamino)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile US11702414, Example 199
BDBM662776 5-[(1S)-1-(3,5-dichloro-2- fluoro-4-pyridyl)ethoxy]-3-[6- (2-methylsulfonyl-2,6- diazaspiro[3.3]heptan-6-yl)-3- pyridyl]-1H-indazole US20240109865, Example 199.
BDBM752769 US20250197407, Compound 199 3-ethoxy-1,3,8-trimethyl-5-[[(1R)- 1-[3-(1,1-difluoro-2-hydroxy- ethyl)-2-methyl- phenyl]ethyl]amino]pyrrolo[3,2- g]phthalazin-2-one
Preparation of (2S) N-([3-chloro-1-[6-(trifluoromethyl)pyridin-3-yl]-1H-pyrazol-4-yl]methyl)-1-[(4-fluorobenzene)sulfonyl]azetidine-2-carboxamide BDBM535120 US11236046, Example 199
US10040781, Example 199 (R)-5-(4-((4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)amino)-1,3,5-triazin-2-yl)-2-((6-oxopiperidin-3-yl)oxy)benzonitrile BDBM277977
US10544150, Compound 199 BDBM430777 [1,1'-biphenyl]-4-yl(3-(2-(((4-chlorophenyl)sulfonyl)methyl)thiazol-4-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone
US10865208, Compound I-199 BDBM476144 [(2R,3S,5R)-5-{4-amino-3-[(3-methoxyphenyl)sulfanyl]-1H-pyrazolo[3,4- d]pyrimidin-1-yl}-3-hydroxytetrahydrofuran-2-yl]methyl sulfamate
US11274108, Example 1-199 3-((2-(6-(1,1-difluoroethyl)pyridin-3-yl)-8-methoxy-2,3- dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-3H-imidazo[4,5- b]pyridine BDBM542920
US9687479, 199 3-(5-[(5-chlorothiophen-2-yl)methyl]amino-1-[(thiophen-3-yl)carbonyl]-1H-pyrazol-3-yl)-1-(pyridin-3-ylmethyl)-1,2-dihydropyridin-2-one BDBM163278
US9783527, Example 199 1-[1-(2-fluorophenyl)-1H- BDBM344897 1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[(5-methyl-1,2-oxazol-3-yl)methyl]imidazolidin-2-one